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Archive for the ‘Blindness’ Category

Charles pays tribute to Malawi’s elimination of disease causing blindness – Express & Star

Saturday, October 15th, 2022

The King has praised Malawi for its remarkable success in eliminating the infectious disease trachoma which causes blindness.

Charles paid tribute to the hard work, dedication and commitment that led to the breakthrough, in a message to the countrys president, Lazarus Chakwera.

The Countess of Wessex is visiting Malawi to celebrate the achievement and has attended a dinner marking the milestone, before joining guests at Malawis national World Sight Day celebrations on Thursday.

The King said in his message: This is a remarkable success, and a true testament to all those whose hard work, dedication and commitment has led to Malawi becoming the first country in Southern Africa to eliminate this devastating, neglected tropical disease as a public health issue.

Tackling avoidable blindness across the Commonwealth was a cause close to the heart of my beloved mother.

Indeed, the Queen Elizabeth Diamond Jubilee Trust, set up in 2012 to create an enduring legacy for her, took the elimination of trachoma as a major part of its mission.

I am particularly proud that Malawi is the first country supported by the Trust to reach the extraordinary milestone of trachoma elimination.

The World Health Organisation (WHO) announced a few weeks ago it had validated Malawis elimination of trachoma as a public health issue, making it the fourth country in WHOs African Region after Ghana (June 2018), Gambia (April 2021) and Togo (May 2022) to achieve this significant milestone.

Sophie is visiting Malawi in her role as a global ambassador for the International Agency for the Prevention of Blindness, and as former vice patron of the Queen Elizabeth Diamond Jubilee Trust.

Charles went on to say: The commitment made by so many Commonwealth leaders at the Malaria and Neglected Tropical Diseases summit in Kigali a few months ago gives me great encouragement that other countries will be inspired by your achievement and, thus, redouble their efforts to eliminate trachoma along with other such diseases.

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Charles pays tribute to Malawi's elimination of disease causing blindness - Express & Star

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Coping with calamity: Former NYT columnist Frank Bruni on blindness and vision, at Morristown book fest keynote – Morristown Green

Saturday, October 15th, 2022

Frank Bruni has seen many people and places over the last quarter-century as a correspondent and columnist for the New York Times.

Because of a rare vision disorder, he now lives with the knowledge that soon he may not see anything.

Bruni, 57, writes about taming that anxiety, and about aging and the hard-earned wisdom it brings, in The Beauty of Dusk, On Vision Lost and Found. On Friday, he kicked off the ninth Morristown Festival of Books in a free-wheeling, often humorous conversation with MSNBC anchor Katy Tur.

If you focus on all the bad that can happen that will become your life, that fear, that paralysis. What have you accomplished? Bruni said during the hour-long keynote at the Mayo Performing Arts Center, where he also touched on politics, the pitfalls of social media, the process of writing, and the pressures of college admissions.

The festival and its junior spinoff, KidFest, continue all day Saturday, Oct. 8, 2022, with free talks in downtown churches and the library by 60 authors. Tickets are $60 for the closing session with best-selling author James Patterson (Blowback).

Bruni awakened one morning in late 2017 with blurry vision in his right eye. Doctors told him a rare stroke had cut off blood to an optic nerve, rendering that eye functionally blind. They warned of a 20 percent chance the same thing could happen in his left eye.

For months, he faced the dawn with anxiety: Would he wake up blind?

A pair of clinical trials were dead ends. One study involved a series of injections directly into his faulty eyeball. Clamped eyelids kept him from blinking.

So you feel like youre Malcolm McDowell in A Clockwork Orange, Bruni recounted, to laughter from the large crowd.

The Beauty of Dusk offers examples of people persevering despite major disabilities a limb lost in wartime, early-onset Parkinsons disease, blindness. Many times we avoid asking individuals about their afflictions, out of politeness or concerns about making them uncomfortable. These are missed opportunities for insights, according to Bruni, who discovered that people were eager to share their stories for his book.

Gradually, he adopted a sunny view of his situation.

I think for a lot of us, there is a zone in which we can choose to be more positive or negative, Bruni said.

You can decide to be angry, and legitimately so. Where does that get you? You can decide to do a tally of all the things that are unavailable to youWhere does that get you? Or you can say, What do I have left?'

Driving at night has become problematic, and parallel parking is out. Reading can be a struggle. Yet Bruni knows things could be worse.

How lucky am I, or any of us who have vision disabilities, to be living at a moment in time when you can control the font size of just about everything?

Bruni said he even scammed the Times into sending him to a Greek island, the source of one of his trial drugs.

Bruni became a media professor at Duke University last year. He has covered the White House, the Persian Gulf War, and the AIDS crisis. Times assignments included Rome bureau chief, restaurant critic, and columnist; he also has appeared regularly on CNN and taught at Princeton. The Beauty of Dusk is his fifth book.

His most popular work, Where You Go Is Not Who Youll Be, took aim at college admissions.

I think weve done a hideous disservice to young people by changing their middle school and high school experiences into this terrifying period whereeverything they do is passed through the prism of how this will look to a bunch of strangers in Princeton, New Jersey, Bruni said.

Its really parents who have to change this, stop telling their kids that this school is better than that school because it rejects more people.

Fielding audience questions, Bruni and Tur who on Saturday will discuss her second book, Rough Draft agreed that writing is hard.

I kind of hate it, said Tur, 38, who anchors MSNBCs Katy Tur Reports. Her advice: Let the words cascade, then start pruning.

Although Bruni once banged out an Ivanka Trump column in 20 minutes, other pieces could take hours, he said. I dont have a process. Just a lot of hope and a keyboard.

When words dont come, he advised pausing. Take a run. Take a showerhave a cocktail.

Bruni and Tur said they dread man on the street interviews. They also admitted suffering from Imposter Syndrome, described by Tur as the fear that interview subjects will think youre an idiot.

Both were critical of social media. Blasted repeatedly by President Trump, Tur turned off her Twitter account before publishing her best-seller Unbelievable, My Front-Row Seat to the Craziest Campaign in American History.

Its a liberating feeling to release yourself from that jail, she said. It can ruin you. In reality, Twitter is a very small portion of the population who have not-representative opinions about most issues.

It was supposed to be a means and a tool of connection, and its become an agent of division, Bruni added. People use social media to hunker down deeper and more consistently in their own micro-tribes.

Most importantly, a young listener wanted to know how Bruni, a University of North Carolina graduate, feels about teaching at archrival Duke. Bruni got booed for that new affiliation while delivering a commencement address at his alma mater.

When the Tar Heels play the Blue Devils in basketball, Im Switzerland, Bruni insisted.

I view it all with anthropological curiosity.

MORE ABOUT THE 2022 MORRISTOWN FESTIVAL OF BOOKS

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Coping with calamity: Former NYT columnist Frank Bruni on blindness and vision, at Morristown book fest keynote - Morristown Green

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Sighting solutions in a world of vision for weavers – The New Indian Express

Saturday, October 15th, 2022

Express News Service

CHENNAI: It was during the pandemic that FM RadioCity received a call from Suresh, a weaver describing his tough fight with cataract and a plea for help as his profession depended on his vision. Providing a solution to the problem, Dr Mohan Rajan, chairman and medical director, Rajan Eye Care Hospital, collaborated with RadioCity and provided free checkup and treatment to the weaver. This initiative that began for Suresh has now extended as the Weavers Vision Project, serving 10,000 weavers in the silk belt ofthe state.

Service for a lifetime

Celebrating World Sight Day 2022 at the Rajan Eye Care Hospital, T Nagar, organised by Chennai Vision Charitable Trust and Rotary Rajan Eye Bank, the event witnessed the distribution of privilege cards to the weavers of Thiruvannamalai, Kanchipuram, Cheyyar, Vellore and Arani. Dr Vishnu Prasad, MP, gave the cards to almost 300 weavers, and applauded the initiative. The privilege cards will authorise the weavers to get free consultations, retino surgery, glasses and other eye health services, free for their entire life, said Dr Mohan. He also educated the audience on the importance of eyesight and the awareness of eye related problems. India contributes to 1/5th of the global blindness with 25 million people affected by blindness. If a kid loses his/her eyesight, he or she will lose 33 working years. For adults it is eight years of loss of working years, he explained.

Initiatives through years

The event also shed light on the fact that India is the largest producer of blindness, cataract disease and children with blindness in the world. Even though there is the case of curable blindness due to various reasons like cracker injury, diapetic retinopathy, short-sightedness or long-sightedness, the doctors confirmed that most people arent aware of the treatment they had to undergo and the various schemes available for reducing the economic burden on these treatments. Providing a solution to the array of problems, Rajan Eye Care started their eye bank in 1991.

With several ambassadors, the project has reached millions of people and the institution continues to spread awareness on corneal blindness and the importance of eye donation. In 2005 their initiative, Blind Free India - A Reality, started organising eye donation rallies every year, reiterating the slogan, Daanathil siranthathu Kandanam, Kankale erikartheerkal, puthaikartherkal (The greatest donation is eye donation, dont bury or burn them).

The hospital also took the tertiary eye care services to the rural doorstep. Now, the latest initiative empowering the weaving community aims to create a better future for them and provide help to a major part of the working sector of the country. Guest of honour, Dr Nandakumar N, district governor, R.I Dist 3232, summed up, We need to support weavers and understand that their job is a seasonal play and requires a lot of effort. With collaborations like this, we can provide help to more people.

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Sighting solutions in a world of vision for weavers - The New Indian Express

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Blindfold run raises $40,000 for the MUHC Foundation to support glaucoma care at the MUHC – StreetInsider.com

Saturday, October 15th, 2022

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MONTREAL, Oct. 13, 2022 (GLOBE NEWSWIRE) -- Quebecers will have access to better glaucoma care thanks to one intrepid ophthalmologist. Dr. Hady Saheb, a glaucoma specialist at the MUHCs McGill Academic Eye Centre (MAEC), pledged to run 50km while blindfolded to raise $40,000 for the MUHC Foundation in support of glaucoma care. With the help of a sighted guide, he completed his run and raised $40,000 the process.

I treat patients who have become blind or have a medical condition that could cause vision loss.Blindness is one of the most devastating conditions a patient can live through, and glaucoma is one of the leading causes of blindness in Canada and worldwide. With better awareness we can prevent blindness. I ran blindfolded because I wanted to put myself in the shoes of those who live with vision loss and blindness, and better understand their struggles and fears.

Dr. Hady Saheb, Glaucoma specialist and ophthalmologist, McGill Academic Eye Centre, McGill University Health Centre

Dr. Saheb completed his final 5km on Friday, October 7th with supporters looking on. He hopes that his run will raise awareness of glaucoma and encourage more people to have regular eye exams. The funds raised will support equipment and programs to help individuals living with glaucoma, vision loss and blindness receive the very best care.

We are inspired by Dr. Sahebs determination and empathy. He already provides life-changing care in his clinic every day, but he went the extra milequite literallyto ensure the well-being of his patients. We are grateful to him for his support of the MUHC Foundation, which will in turn provide important resources to the McGill Academic Eye Centre.

Julie Quenneville, President and CEO, McGill University Health Centre Foundation

Glaucoma is one of the leading causes of blindness for people over 60 years of age. The most common form is caused by a build-up of pressure in the eye. The pressure damages the optic nerve, leading to vision loss or blindness. Most frightening of all, glaucoma can develop without warning signs, putting more individuals at risk. Thanks to Dr. Saheb, fewer Quebecers will experience blindness as a result of glaucoma.

About the McGill University Health Centre Foundation

The McGill University Health Centre (MUHC) Foundation raises funds to support excellence in patient care, research and teaching at the McGill University Health Centre, one of the top university hospitals in Canada. Our Dream Big Campaign to change the course of lives and medicine is raising millions of dollars to solve humanitys deadliest puzzles: infectious diseases; end cancer as a life-threatening illness; fix broken hearts through innovative cardiac care; detect the silent killersovarian and endometrial cancersearly; create the best skilled health care teams in Canada; and much more. We are rallying our entire community to solve the worlds most complex health care challenges.

Tarah Schwartz Director, Communications & MarketingMcGill University Health Centre Foundation [emailprotected]

Kelly AlbertSenior Communications OfficerMcGill University Health Centre Foundation [emailprotected]

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/bc9096a3-9224-40c2-ad20-54c1e72492f2

Blindfold Run raises $40 000 for the MUHC Foundation

Dr. Hady Saheb and Dr. Sherin Al-Safadi

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MacKenzie Scott Donates $15M to Address the Eyecare Needs of the Impoverished – InvisionMag

Saturday, October 15th, 2022

MacKenzie Scott is known for her philanthropy. If fact, shes rewriting the philanthropy playbook.

Makes sense in a way. She is an author.

When Scott and Amazon founder Jeff Bezos divorced in 2019, she instantly became one of the richest people in the world. Shortly thereafter she declared her intention to donate her entire fortune approximately $38 billion to charity. She seems to be right on track.

Scott eclipsed the $12 billion mark in lifetime donations earlier this year. Shes already donated to more than 1,200 organizations. Her philanthropy efforts havent skipped a beat since the recent announcement that she filed for divorce from her second husband.

VisionSpring announced today it is the most recent recipient of Scotts charity. The nonprofit accepted a $15 million gift from Scott. The money will go toward the organizations new initiative Livelihoods in Focus, a $70 million effort to correct the vision of more than 6 million people by 2030.

VisionSprings mission is to bring affordable eyewear to some of the poorest areas in the world. Scotts donation is believed to be the largest single private donation toward addressing the eyecare needs of individuals in poverty.

VisionSpring said it will focus on low-income tea, coffee, cocoa and artisan workers in India, Bangladesh, Ghana, Kenya and Uganda. To donate to VisionSpring click on this link.

World Sight Day is observed around the world every second Thursday in the month of October. Lions Club International started the observance in 2000 as part of its annual SightFirst campaign to fight blindness. The International Agency for the Prevention of Blindness (IAPB) joined the initiative that year as well.

It has become a global day of awareness and giving for those in need of adequate eyecare.

The INVISION Magazine e-mail inbox is proof. Weve received numerous correspondences highlighting World Sight Day-centric initiatives.

It truly is inspiring.

The World Council of Optometry (WCO) joined forces with IAPB to promote their #loveYourEyes campaign. The goal was to get 5 million eye tests pledged globally from September 13 to October 13. That impressive number was eclipsed with a day to spare.

Warby Parker has teamed with Jonas Philanthropies to address vision disability with the Warby Parker Pupils Project. The initiative, which began in 2015, gives children access to proper vision care by taking vision screenings and eye exams to their classrooms. It is taking place in New York City, Washington, D.C., Baltimore, California and Pennsylvania. Warby Parker is known for its buy a pair give a pair that gives glasses to individuals in need. Jonas Philanthropies in 2016 launchedJonas Childrens Vision Careto prevent blindness and treat vision disorders.

SightSavers is marking World Sight Day 2022 with a new Eye Health Equals campaign along with a manifesto for change directed at world governments. The non-profit works on preventable blindness in more than 30 counties, primarily in Africa and Asia. The group is calling on world governments to:

And, lastly, dont forget that the IAPB World Sight Day 2022 Photo Competition continues through Oct. 22. It is open to both amateur and professional photographers. Submitted images should capture what it means to have healthy vision. Photos will be judged in five categories: Your Eyes, Health for All, Everyone Everywhere, Hope, and Eye-Sights. You can submit your photos by following this link.

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MacKenzie Scott Donates $15M to Address the Eyecare Needs of the Impoverished - InvisionMag

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Astellas and MBC BioLabs Announce Astellas Future Innovator Prize to Help Biotech Start-ups Accelerate Early Drug Discovery and Research Efforts -…

Tuesday, September 20th, 2022

Sponsorship provides a year of access to MBC BioLabs' life-science incubators and in-house Astellas expertise for scientific innovators

TOKYOandSAN FRANCISCO, Sept. 19, 2022 /PRNewswire/ -- Astellas Venture Management LLC (President:William Watt, Ph.D., "AVM"), a wholly-owned venture capital subsidiary of Astellas Pharma Inc. (TSE: 4503,President and CEO:Kenji Yasukawa, Ph.D., "Astellas"), and Mission Bay Capital BioLabs ("MBC BioLabs"), a life-science incubator, today announced their collaboration on the "Astellas Future Innovator Prize" formerly known as the Astellas Golden Ticket competition. Building on over three successful years, the competition offers entrepreneurial scientists or emerging biotechnology start-ups one year's priority usage of MBC BioLabs' state-of-the-art lab facility and access to Astellas' research and development (R&D) capabilities and business leaders.

With a shared commitment to discovering and advancing innovative science for the potential future benefit of patients worldwide, AVM and MBC BioLabs are continuing their partnership to support scientists and early-stage companies to accelerate their novel therapeutic programs, modalities or platforms. The 2022 competition will prioritize innovative research that compliment Astellas' Focus Area Approach and pipeline.

"We are truly thrilled to host the Astellas Future Innovator Prize again this year," said William Watt, President, AVM. "Through our long-term collaboration with MBC BioLabs, we aim to create an environment that encourages innovation to thrive. The Astellas Future Innovator Prize enables us to provide biotech companies with expertise and capabilities to turn an innovative idea into a real solution, which could transform the lives of patients in need around the world."

"We are pleased to continue our partnership with Astellas to uncover the innovators of tomorrow," saidDouglas Crawford, MBC BioLabs General Manager. "The past winners of the Astellas Future Innovator Prize show what can be achieved by combining Astellas' support, advice and expertise with our laboratory incubator, and we are excited to see the result of our ongoing collaboration."

Entrepreneurial scientists, emerging life-science and biotechnology start-ups have untilNovember 4, 2022to enter the Astellas Future Innovator Prize.

About the Astellas Future Innovator Prize at MBC BioLabs

Astellas is offering up to two prizes for pioneering scientists with innovative research that complements Astellas' areas of interest in alignment with its Focus Area Approach and pipeline, including Blindness & Regeneration, Mitochondria, Genetic Regulation, Immuno-Oncology, Cell Therapy, and other areas.

Companies awarded an Astellas Future Innovator Prize will gain one year's priority admission or renewal to MBC BioLabs' state-of-the-art laboratory and access to Astellas' R&D scientists and business leaders. The competition is open fromSeptember 19 to November 4, 2022. Entrepreneurial scientists, emerging life-science or biotechnology start-ups should submit their non-confidential company presentation, including a one-page executive summary, tohttps://www.astellas.com/en/astellasfutureinnovator/san-francisco2022to be considered. The decision to award any Astellas Future Innovator Prize and the assessments underlying such decision, are solely within the judgment of Astellas and are not subject to any objection or appeal.

The 2021 Astellas Future Innovator Prize winners were Vcreate and Weatherwax Biotechnologies, chosen for the potential of their innovations to deliver therapeutic advances for unmet medical needs and their potential synergy with Astellas' Focus Area Approach.

For further information, please go to:https://www.astellas.com/en/astellasfutureinnovator/, where you can also find submission guidance for your non-confidential company presentation and executive summary.

About Astellas Venture Management LLC

AVM is the wholly-owned venture capital organization within Astellas, dedicated to supporting pre-clinical, cutting-edge science that can bring VALUE to patients. For over 15 years, AVM has provided equity investments to private, early-stage companies developing therapeutic programs and platform technologies, helping them to advance their innovations faster. AVM is a strategic investor, making investments in science that will enhance the current Astellas R&D pipeline or that could catalyze new directions in discovery research. For more information, please visit our website athttps://www.astellas.com/en/astellasfutureinnovator/.

About Astellas

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are promoting the Focus Area Approach that is designed to identify opportunities for the continuous creation of new drugs to address diseases with high unmet medical needs by focusing on Biology and Modality. Furthermore, we are also looking beyond our foundational Rx focus to create Rx+healthcare solutions that combine our expertise and knowledge with cutting-edge technology in different fields of external partners. Through these efforts, Astellas stands on the forefront of healthcare change to turn innovative science into value for patients. For more information, please visit our website athttps://www.astellas.com/en.

About MBC BioLabs

MBC BioLabs is dedicated to helping life-science startups succeed. By renting space as small as a single bench and providing these entrepreneurial scientists with access to millions of dollars of equipment, MBC BioLabs allows companies to be fast, focused, and frugal. It has three sites: one in the Dogpatch neighborhood inSan Franciscoand two campuses inSan Carlos, California. Each site has a complete molecular biology core facility that allows companies to do experiments on day one. MBC BioLabs has partnerships with leading pharmaceutical and life-science companies as well as a built-in venture capital firm, Mission BioCapital. These partnerships provide entrepreneurs with valuable insights about where to focus their efforts and accelerates the innovation pipeline. Since opening in 2013, MBC BioLabs has helped launch and grow 290 companies. These companies have brought 58 programs to the clinic, produced 13 approved diagnostics, and raised over $14 billion.

Cautionary Notes

In this press release, statements made with respect to current plans, estimates, strategies and beliefs and other statements that are not historical facts are forward-looking statements about the future performance of Astellas. These statements are based on management's current assumptions and beliefs in light of the information currently available to it and involve known and unknown risks and uncertainties. A number of factors could cause actual results to differ materially from those discussed in the forward-looking statements. Such factors include, but are not limited to: (i) changes in general economic conditions and in laws and regulations, relating to pharmaceutical markets, (ii) currency exchange rate fluctuations, (iii) delays in new product launches, (iv) the inability of Astellas to market existing and new products effectively, (v) the inability of Astellas to continue to effectively research and develop products accepted by customers in highly competitive markets, and (vi) infringements of Astellas'intellectual property rights by third parties.

Information about pharmaceutical products (including products currently in development) which is included in this press release is not intended to constitute an advertisement or medical advice.

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SOURCE Astellas Pharma Inc.

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Treating cataracts before ‘critical age’ imperative FBC News – FBC News

Tuesday, September 20th, 2022

A child getting her eyes checked.

Eye disease such as cataracts is a leading cause of blindness globally and affects a lot of our elderly in Fiji as well.

However, children are not being spared as cataract cases in our young are normally congenital or pediatric.

Pacific Eye Institute Ophthalmologist, Dr Elenoa Raikabakaba says cataracts naturally happen in older patients and is not as common in children.

Some cataracts are associated with other syndromes. The cases we have here, some are associated with other systemic diseases and for some, its of course trauma.

Dr Raikabakaba says early treatment in children is imperative before they reach what is called a critical age.

There is something called critical age so if your child is past the critical age, and if you are waiting for those to be adults and then you treat it; it may not improve their vision. If you think your child needs help, get them to be seen.

Specialists at the Pacific Eye Institute are calling on Fijians to get their eyes checked if they have difficulties with their eyesight and seek proper medical treatment.

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GenSight Biologics to Present at Upcoming Industry and Investor Conferences – Business Wire

Tuesday, September 20th, 2022

PARIS--(BUSINESS WIRE)--Regulatory News:

GenSight Biologics (Euronext: SIGHT, ISIN: FR0013183985, PEA-PME eligible), a biopharma Company focused on developing and commercializing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders, today announced that the Company will participate in the following industry and investor conferences:

The Business of Rare Policy SummitSeptember 20, 2022 - Washington DC, USBernard Gilly, Co-Founder & Chief Executive Officer, will take part in a panel discussion entitled "Business of Rare: State of the Industry" at 11:15 am EDT / 5:15 pm CEST.

GenSight Biologics is a headline sponsor of the conference and will also host a reception entitled "A Rare Pairing" at 4:30 pm EDT / 10:30 pm CEST.

Chardan's 6th Annual Genetic Medicines ConferenceOctober 3 - 4, 2022 - New York, USBernard Gilly, Co-Founder & Chief Executive Officer, and Thomas Gidoin, Chief Financial Officer, will attend in person on October 4, 2022, present in a fireside chat at 2.30 pm EDT / 8.30 pm CEST, and host investor meetings.

The fireside chat will be webcast live and in replay using this link.

4th Annual HealthTech Innovation Days (HTID) 2022October 13 - 14, 2022 - Paris, France & VirtualBernard Gilly, Co-Founder & Chief Executive Officer, and Thomas Gidoin, Chief Financial Officer, will attend in person and host investor meetings.

BTIG Ophthalmology Day 2022November 29, 2022 - VirtualBernard Gilly, Co-Founder & Chief Executive Officer, and Thomas Gidoin, Chief Financial Officer, will participate and host investor meetings.

About GenSight Biologics

GenSight Biologics S.A. is a clinical-stage biopharma company focused on developing and commercializing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders. GenSight Biologics pipeline leverages two core technology platforms, the Mitochondrial Targeting Sequence (MTS) and optogenetics, to help preserve or restore vision in patients suffering from blinding retinal diseases. GenSight Biologics lead product candidate, LUMEVOQ (GS010; lenadogene nolparvovec), is an investigational compound and has not been registered in any country at this stage; a marketing authorization application is currently under review by the EMA for the treatment of Leber Hereditary Optic Neuropathy (LHON), a rare mitochondrial disease affecting primarily teens and young adults that leads to irreversible blindness. Using its gene therapy-based approach, GenSight Biologics product candidates are designed to be administered in a single treatment to each eye by intravitreal injection to offer patients a sustainable functional visual recovery.

About LUMEVOQ (GS010; lenadogene nolparvovec)

LUMEVOQ (GS010; lenadogene nolparvovec) targets Leber Hereditary Optic Neuropathy (LHON) by leveraging a mitochondrial targeting sequence (MTS) proprietary technology platform, arising from research conducted at the Institut de la Vision in Paris, which, when associated with the gene of interest, allows the platform to specifically address defects inside the mitochondria using an AAV vector (Adeno-Associated Virus). The gene of interest is transferred into the cell to be expressed and produces the functional protein, which will then be shuttled to the mitochondria through specific nucleotidic sequences in order to restore the missing or deficient mitochondrial function. LUMEVOQ was accepted as the invented name for GS010 (lenadogene nolparvovec) by the European Medicines Agency (EMA) in October 2018. LUMEVOQ (GS010; lenadogene nolparvovec), is an investigational compound and has not been registered in any country at this stage; a marketing authorization application is currently under review by the EMA.

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GenSight Biologics to Present at Upcoming Industry and Investor Conferences - Business Wire

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Ashton Kutcher battled vasculitis causing blindness, loss of hearing. Know all about the rare condition – India TV News

Thursday, August 11th, 2022

Ashton Kutcher has opened up about being diagnosed with a "rare form of vasculitis", an autoimmune disease that left him unable to see, hear, or walk. The Two And A Half Men actor shared the diagnosis in the Monday episode of the National Geographic show, Running Wild with Bear Grylls: The Challenge. "Like two years ago, I had this weird, super rare form of vasculitis, that like knocked out my vision, it knocked out my hearing, it knocked out like all my equilibrium," Kutcher said in a clip shared by entertainment programme Access Hollywood.

In the video, the 44-year-old further said it took him a year to build his life from scratch and that he was "lucky to be alive". After the clip went viral on social media, Kutcher posted a clarification on Twitter, saying the health scare happened three years ago following which he had made a full recovery.

Let's find out whatvasculitis is that affected Kutcher severely.

Vasculitis is inflammation of a blood vessel or blood vessels.The inflammation can cause the walls of the blood vessels to thicken, which reduces the width of the passageway through the vessel. If blood flow is restricted, it can result in organ and tissue damage.Vasculitis may affect anyone regardless of age or other factors. It may be treated with medication that controls the inflammation and prevents flare-ups.

Kutcher revealed that due to hisVasculitis, he was unable to 'see, hear, or walk'.This is a possible complication of untreated giant cell arteritis, whichcan cause double vision and temporary or permanent blindness in one or both eyes. Some types of vasculitis can cause numbness or weakness in a hand or foot. The palms of the hands and soles of the feet might swell or harden.Dizziness, ringing in the ears and abrupt hearing loss may also occur, as per Mayo Clinic.

Read:Can Monkeypox spread through sex? Experts answer who are at high risk for transmission

General symptoms of vasculitis include: fever, headache, fatigue, weight loss, general aches and pains. Other signs and symptoms are related to the parts of the body affected. Vasculitis may turn severe and requires treatment and expert care. So if any of the mentioned symptoms show up or persist, seeing a doctor is recommended. Mostly, vasculitis can be treated with medication and proper medical oversight.

Read:Can stress be good for brain functioning? Here's what the researchers have to say

(With PTI inputs)

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Prevent Blindness Is Recognized as a Healthy People 2030 Champion for Supporting the Initiative’s Vision – Vision Monday

Thursday, August 11th, 2022

VM - Prevent Blindness Is Recognized as a Healthy People 2030 Champion for Supporting the Initiatives Vision PEOPLE: Honors By Staff Friday, August 5, 2022 12:24 AM CHICAGOPrevent Blindness, the nations leading voluntary eye health and safety nonprofit organization, has been recognized by the Office of Disease Prevention and Health Promotion (ODPHP) within the U.S. Department of Health and Human Services (HHS) as a Healthy People 2030 Champion. As a Healthy People 2030 Champion, Prevent Blindness has demonstrated a commitment to helping achieve the Healthy People 2030 vision of a society in which all people can achieve their full potential for health and well-being across the lifespan.ODPHP recognizes Prevent Blindness, along with other Healthy People 2030 Champions, as part of a growing network of organizations partnering with ODPHP to improve health and well-being at the local, state and tribal level.Prevent Blindness has been a collaborator with the Healthy People Initiative for several decades. Objectives for the Healthy People 2030 program align with the Prevent Blindness sight-saving mission in a variety of areas, including childrens vision, diabetes, falls prevention, eye safety, access to care for underserved populations and more.At Prevent Blindness, we are excited that vision and eye health are included as key components in the overall objectives for Healthy People 2030, said Jeff Todd, president and CEO of Prevent Blindness. We look forward to working closely with the ODPHP and other partners in advancing education, awareness and access to care for millions of Americans.Healthy People 2030 is the fifth iteration of the Healthy People initiative, which sets 10-year national objectives to improve health and well-being nationwide. Healthy People 2030 Champions are public and private organizations that are working to help achieve Healthy People objectives. They receive official support and recognition from ODPHP.ODPHP is thrilled to recognize Prevent Blindness for its work to support the Healthy People 2030 vision, says RADM Paul Reed, MD, ODPHP director. Only by collaborating with partners nationwide can we achieve Healthy People 2030s overarching goals and objectives.For more information about Prevent Blindness and a variety of vision and eye health topics, please visit PreventBlindness.org. For more information on Healthy People 2030, please visit Health.gov/healthypeople.Healthy People 2030 Champion is a service mark of the U.S. Department of Health and Human Services. Used with permission. Participation by Prevent Blindness does not imply endorsement by HHS/ODPHP.

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Researchers make progress toward a stem cellbased therapy for blindness – Ophthalmology Times

Thursday, August 11th, 2022

What if, in people with blinding retinal disorders, one could simply introduce into the retina healthy photoreceptor cells derived in a dish from stem cells, and restore sight?

According to a news release form the University of Pennsylvania, it is a straightforward strategy to curing blindness, yet the approach has been met with a number of scientific roadblocks, including introduced cells dying rapidly or failing to integrate with the retina.

A new study, published in Stem Cell Reports, overcomes these challenges and marks significant progress toward a cell-based therapy. The work, led by a team at the University of Pennsylvania School of Veterinary Medicine, in collaboration with researchers at the University of Wisconsin-Madison, Childrens Hospital of Philadelphia, and the National Institutes of Healths National Eye Institute (NEI), introduced precursors of human photoreceptor cells into the retinas of dogs. A cocktail of immunosuppressive drugs enabled the cells to survive in the recipients retinas for months, where they began forming connections with existing retinal cells.

In this study, we wanted to know if we could, one, improve the surgical delivery of these cells to the subretinal space; two, image the cells in vivo; three, improve their survival; and four, see them migrate to the layer of the retina where they should be and start integrating, said William Beltran, a professor of ophthalmology at Penn Vet and senior author on the study. The answer to all those questions was yes.

Beltran and Gustavo Aguirre at Penn Vet have long been interested in addressing retinal blinding disorders and they have had great successes to date at producing corrective gene therapies for conditions with known causative genes. But for many cases of inherited retinal degeneration, a gene has not been identified. In other patients, the disease has progressed so far that no photoreceptor cells remain intact enough for gene therapy. In either scenario, a regenerative medicine approach, in which photoreceptors could be regrown outright, would be extremely valuable.

To develop a cell therapy, Beltrans team joined with groups led by John Wolfe of CHOP and Penn Vet; David Gamm at the University of Wisconsin-Madison; and Kapil Bharti at the NEI, in a consortium supported by the NEIs Audacious Goals Initiative for Regenerative Medicine. The partnership combined Beltrans teams expertise in canine models of retinal degeneration and vast experience in cell-based therapy approaches from the Wolfe, Gamm, and Bharti labs.

According to the news release, photoreceptor cells, which are made up of rods and cones, constitute a layer of the outer retina critical to initiating the process of vision, whereby the energy of light transforms into an electrical signal. To function properly, they must form a connection, or synapse, with cells of the inner retina to pass along the visual information. Thus, the goal of this cell therapy is to recreate this layer and enable it to integrate with the retinas other cell types in order to relay signals from one layer to the next.

In the current work, the team used stem cellderived precursors of human photoreceptor cells developed in the Gamm lab to serve as the basis of the cell therapy. In collaboration with the Bharti lab, they developed a new surgical approach to inject the cells, which were labeled with fluorescent markers, into the retinas of seven dogs with normal vision and three with a form of inherited retinal degeneration, then used a variety of non-invasive imaging techniques to track the cells over time.

The use of a large animal model that undergoes a naturally occurring form of retinal degeneration and has a human-size eye was instrumental to optimize a safe and efficient surgical procedure to deliver doses of cells that could be used in patients, Gamm said in the news release.

The researchers observed that cell uptake was significantly better in the animals with retinal degeneration compared to those with normal retinas.

What we showed was that, if you inject the cells into a normal retina that has its own photoreceptor cells, the retina is pretty much intact and serves as a physical barrier, so the introduced cells dont connect with the second-order neurons in the retina, the bipolar cells, Beltran noted in the news release. But in three dogs that were at an advanced stage of retinal degeneration, the retinal barrier was more permeable. In that environment, cells had a better ability to start moving into the correct layer of the retina.

Because the transplanted human cells could be interpreted by the dogs immune system as foreign entities, the researchers did what would be done in other tissue transplant procedures: They gave the dogs immunosuppressive drugs. The trio of medications had been tested previously by Oliver Garden, a veterinary immunologist with Penn Vet at the time of the study, who is now dean of Louisiana State University School of Veterinary Medicine.

Indeed, while the injected cell populations declined substantially in dogs that did not receive the immune-suppressing drugs, the cell numbers dipped but then sustained in the dogs that received the cocktail.

The university noted that further characterization of the introduced cells revealed evidence of potential synapses.

We saw that yes, some are appearing to shake hands with those second-order neurons, Beltran added in the release. There appeared to be contact.

The next stage for this project will be to continue optimizing the therapy, and then test whether there is a functional responsein other words, improved visionin its recipients.

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UND professor carries the torch for UND studies of visual impairment and blindness – Grand Forks Herald

Thursday, August 11th, 2022

GRAND FORKS Assistant Professor Renae Bjorg is carrying on a UND legacy in the field of visual impairments and blindness.

With her new book Guidelines and Games for Teaching Efficient Braille Reading (Second Edition), she continues the work of a longtime UND professor and her former mentor, Myrna Olson.

The first edition of Guidelines and Games'' was published in 1981, and was written in part by Olson, a UND professor of almost 50 years, and Sally Mangold, professor at San Francisco State. Since it was published 40 years ago, the book has remained one of the most popular resources for teachers learning how to teach students braille.

Bjorg said she was approached by American Printing House Press to write the book for the 40th anniversary of the first edition.

The updated edition, says Bjorg, includes new information about technological advances from the last 40 years, as well as updated terminology and research. The new edition also has more of a focus on bridging the gap between students who can see and students who are visually impaired or blind when learning to read.

Were still teaching reading and writing, said Bjorg. Its still English language arts, its just a different modality now Braille instead of print, but its still the same.

And like learning to read can be made fun for seeing students, learning to read can be fun for visually impaired or blind students as well. Board games and word games can be used to teach seeing students to read and write, so the book outlines similar games for those that cannot see.

When we can learn to make it fun and incorporate ergonomics and posture, then students, children and teachers can enjoy the process and enjoy the full learning and apply it in a natural way, said Bjorg.

Many of Bjorgs collaborators for Guidelines and Games were her advisees at UND that have gone on to work in the field of education and visual impairment and blindness, like Sara Careless, Sandra Kenrick, Danielle Moelter-Swangstue and Amy Neils.

We all have strengths and abilities, and part of my job as an adviser and a professor is to look at my students and pull these things out of them, she said. These students that I invited are beautiful writers and researchers, and highly qualified teachers in our field.

Others, like Laura Roy, coordinator of the Blind and Visually Impaired Services Unit in Manitoba; Dave Beckett, consultant for the blind and visually impaired in Manitoba, and Brittany Hagan, associate professor at Mayville State University have been impacted by Olson and wanted to give back to her.

Austin Winger, one of Olsons sons, also helped with the book.

Bjorg recently signed books at the Association for Education and Rehabilitation of the Blind and Visually Impaired International Conference in St. Louis, and has been invited to present at the North Dakota State Deafblind Conference and a conference in Nebraska hosted by the Nebraska Center for the Education of Children who are Blind or Visually Impaired.

At the book signing in St. Louis, Bjorg was surprised by the number of people lined up to get a copy of her book signed. At the conference, more than 200 copies were sold.

It was really encouraging, she said. People were so excited to get this book and when I was signing books, people didnt know Myrna Olson because some of the people are new in the field.

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The strategic blindness of Israel’s caretaker government – JNS.org

Thursday, August 11th, 2022

(August 8, 2022 / JNS) Operation Breaking Dawn was a textbook illustration of Israels tactical brilliance and prowess on the one hand, and strategic blindness on the other.

Tactically, Israels Iron Dome system allows its civilians to remain almost entirely unharmed while terror armies pummel Israels cities and villages with missiles and rockets. So too, Israel has developed precision-guided weapons and operational intelligence capabilities which in combination enable it to conduct pinpoint assaults against targets and destroy them with little to no collateral damage.

From Friday through Sunday, Islamic Jihad shot nearly a thousand projectiles at Israel. But largely thanks to Iron Dome, no Israelis were harmed by direct hits. In precision strikes, Israel was able to eliminate Islamic Jihads commanders.

However, while Israels leaders are right to trumpet the operations tactical, technology-based success, Operation Breaking Dawn was a strategic fiasco on multiple levels.

The first level of strategic failure is the operational one. Breaking Dawn was precipitated by Islamic Jihads decision to respond to Israels arrest of its senior operative Bassem Saadi early last week in Jenin with a threat to carry out a mass casualty attack on Israeli civilians and military personnel from Gaza.

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According to Egyptian mediators, Israel agreed to consider releasing Saadi and perhaps another Islamic Jihad terrorist in exchange for a ceasefire. If the Egyptian announcement is accurate, then Islamic Jihad will be able to present its missile assault as a victory. By lobbing a thousand projectiles at Israeli cities from Gaza, the terror group was able to coerce Israel into freeing terrorists in Samaria.

Even better, from Islamic Jihads perspective, for the four days that preceded Israels initiation of Operation Breaking Dawn, the government ordered more than a million Israelis to remain in their homes and closed rail service and the major highways connecting population centers in southern Israel to the rest of the country. That four-day lockdown, based solely on Islamic Jihad threats, was the greatest victory the terror group ever achieved.

Israels operation demonstrated the depth of the strategic challenge Gaza poses. Islamic Jihad is a wholly owned subsidiary of Irans Revolutionary Guards Corps, which founded it in 1988 and still arms and commands its operations today. Islamic Jihad used to be seen as a mere nuisance in the Gaza Strip. But this week it showed it has amassed an arsenal capable of presenting Israel with a massive security challenge. Even worse, it has just a fraction of the capabilities that Hamas enjoys.

Hamas is not a wholly owned subsidiary of Iran, but it is an Iranian client. Hamas receives funding and arms from Tehran. Its leaders are in direct, intimate contact with the Iranian regime, which they brag about. Hamas chief Ismail Haniyeh was in Tehran last April to participate in Iranian President Ebrahim Raisis inauguration. Hamas tens of thousands of missiles cover nearly all of Israel. Its anti-aircraft and anti-tank missiles pose a threat to Israeli ground and air operations in Gaza.

Iranian sponsorship isnt the only thing Hamas and Islamic Jihad share. They are partners. According to media reports, there were Hamas officers in Islamic Jihad command centers all week long. Hamas approved every missile volley Islamic Jihad launched and provided it with logistical support. Given the intimacy of their cooperation, the fact that Hamas didnt use its own missiles to attack Israel is a meaningless distinction. Indeed, its worse than that. Pretending that Hamas is not involved in an operation it actually enabled and participated in gives Hamas a free pass for waging war.

But for the Lapid-Gantz caretaker government, none of this mattered. The government and its attendant media insisted Hamas and Islamic Jihad are totally separate from one another, and even rivals. The governments narrative claimed Hamas was acting like a responsible adult.

Between Friday and Saturday, the IDFs job quickly moved from attacking Islamic Jihad to ending the operation as quickly as possible to avoid Palestinian civilian casualties that would compel Hamas to start shooting its own missiles at Israel. In other words, the government put the onus on itself. Hamas would come in if Israel made a mistake. Hamas is responsible. It cares about its people. And it will only join the fray if Israel forces its hand.

This false narrative is doubly destructive given Hamas actual nature. Hamas isnt a responsible governing authority. Its a terrorist organization ideologically committed to annihilating Israel and the entire Jewish people. By treating Hamas as the responsible adult in the room, the government gave legitimacy to an actor that is morally, militarily, ideologically and politically illegitimate.

This is not to say that Israel should have opened a major campaign against Hamas. A caretaker government lacks the political legitimacy to initiate a large-scale conflict. But the governments kowtowing to Hamas, like its anxious acceptance of Islamic Jihads ceasefire terms, was unnecessary and destructive.

Caretaker Prime Minister Yair Lapid and Defense Minister Benny Gantzs behavior vis--vis Gaza is in keeping with the overall strategic blindness that has afflicted this government in relation not only to Irans Palestinian proxies Islamic Jihad and Hamas, but also to Irans Lebanese legion Hezbollah and, indeed, Iran itself.

Lapid and Gantz are poised to accept a deal to transfer some of Israels sovereign economic waters to Lebanon. There are two concepts behind the deal, negotiated by the Biden administration. First, most importantly and like the White House, Lapid and Gantz insist Lebanon is a political entity separate from Hezbollah. This is entirely false. Hezbollah is the most powerful military organization in Lebanon. It has swallowed the Lebanese Armed Forces, which operate at Hezbollahs pleasure. And it has also swallowed the government, which will not do anything Hezbollah opposes.

The second concept, which flows from the first, is that by enabling Lebanon to develop natural gas fields in the eastern Mediterranean, Israel will empower the government against Hezbollah. This too is entirely false. Hezbollah controls the negotiations. Lebanon will not profit from the deal at Hezbollahs expense. The deal will transform Hezbollahand Iraninto players in the Mediterranean gas industry, opening up a whole new sphere of profit, as well as potential extortion and blackmail of Israel.

As for Iran itself, from the moment they formed their government with their erstwhile partner Alternate Prime Minister Naftali Bennett, Lapid and Gantz opted to subordinate Israels policies towards Iran to the Biden administration. They announced a policy of no surprises, which effectively gave the administration veto power over all Israeli operations against Irans nuclear installations and other offensive operations.

Since the Biden administrations central Middle East policy is to reinstate Barack Obamas 2015 nuclear deal with Iran, the implication of no surprises is that Israel agreed to subordinate its confrontational policy towards Iran to the U.S. policy of appeasing Iran.

Lapid/Gantzs predecessor and nemesis is opposition leader Benjamin Netanyahu. During his long premiership, Netanyahu also sought to avoid major military confrontations with Hamas and Hezbollah. But unlike Lapid and Gantz, Netanyahu did so while adhering to a strategic concept that had the virtue of not only being right, but effective.

Netanyahu recognized that the Palestinians, like Hezbollah, are part of Irans war machine. As Iranian Revolutionary Guard Corps General Asghar Emami said in a May 2021 interview, Iran doesnt need to directly attack Israel because its proxies Hezbollah, Islamic Jihad and Hamas are on Israels borders.

Emami said, Due to our presence in the axis of resistance, we have placed [Israel] under siege. We dont need to send airplanes or missiles to Israel. Now, with our presence in the axis of resistance, we can hit Israel with mortar shells.

Netanyahu adopted an integrated, three-pronged Iran strategy. He sought to deprive Iran of funds to diminish its economic capacity to fund its proxies. He built and used the capacity to carry out near-continuous acts of sabotage against Irans nuclear installations and personnel. And he led Israel in waging a full-scale diplomatic war against Iran.

One of the crowning achievements of Netanyahus strategy was his success in persuading then-president Donald Trump to withdraw from Obamas 2015 deal with Iran. Obamas deal transferred more than $100 billion to Tehran through sanctions relief. Immediately after the deal went into effect in August 2015, Iran began funneling massive funds to Hamas, Islamic Jihad and Hezbollah, as well as the Houthis in Yemen, enabling them to escalate their wars against Israel and the Sunni states. By walking away from the deal and reinstating U.S. economic sanctions on Iran, Trump set Iran on the road to poverty, and its funding for its terror proxies dried up. Had the policy been continued under Biden, Islamic Jihad would likely not have had a thousand missiles of varying ranges to lob at Israel over three days.

Iran crossed the nuclear threshold in recent weeks for two reasons: First, the Biden administration stopped enforcing sanctions and thus emboldened the Iranians to massively increase their levels of uranium enrichment and stockpiles of enriched uranium. Second, Israel dramatically scaled back its operations in Iran as part of the Lapid-Gantz-Bennett no surprises policy.

Netanyahus diplomatic war against Iran, even in the face of U.S. animosity, is what drew the Arab states to Israel. The 2015 nuclear deal threatened the Sunnis no less than it threatened Israel. Netanyahus unapologetic opposition to the agreement drew Saudi Arabia, the UAE, Egypt and Bahrain to Israels side.

As for the Palestinians, Netanyahu largely ignored them. And when he was forced to fight them, he made clear that they were first and foremost Iranian proxies. His argument was convincing because it was accurate. In 2014, recognizing the truth of Netanyahus claim, the UAE, Saudi Arabia and Egypt stood with Israel against Hamas, Turkey, Qatar and the Obama administration, which tried to force Israel to accept Hamas ceasefire demands.

Over the past week, Lapid and Gantz barely mentioned Iran, despite the fact that Islamic Jihads leader Ziad Nahalka was in Tehran the entire time. Their reticence was likely due to the fact that as Irans Palestinian proxy pummeled Israel with missiles and rockets, Bidens negotiators are in Vienna, yet again begging Iran to accept sanctions relief in exchange for a nod to the 2015 nuclear deal. By hiding the fact that Iran stood behind Islamic Jihad/Hamas entire assault, Gantz and Lapid returned the Palestinians to center stage, to devastating effect for Israel.

By giving Iran a free pass, Israel alienated its Arab allies. Instead of supporting Israel, the UAE is co-sponsoring a U.N. Security Council meeting to discuss Israels operation. Saudi Arabia published a full-throated condemnation of Israels operation against an Iranian proxy.

It is easy to understand the logic of a limited campaign. But by carrying it out in a state of strategic blindness, the caretaker government legitimized Hamas and undermined Israels position in the strategic battle of our timesagainst Iran.

Caroline Glick is an award-winning columnist and author of The Israeli Solution: A One-State Plan for Peace in the Middle East.

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Karan Nagrani is using social media to raise awareness about the ‘spectrum of blindness’ – ABC News

Thursday, August 11th, 2022

What comes to mind when you think of blindness?Is it a person donning dark sunglasses, possibly with a cane, or a guide dog?

There are certainly people with vision loss who fit this bill, but for many others, their experience of blindness is not quite so black and white.

Karan Nagrani is legally blind, but if you passed him in the streetit's likely you wouldn't know.

Diagnosed at the age of 11 with a degenerative genetic condition called retinitis pigmentosa, the now 36-year-oldonly has a fraction of his vision remaining.

"It starts off asnight blindness and loss of side vision, and then the central [vision] starts to get affected," Mr Nagrani said.

"When people look ahead, they see 180 degrees I see less than three degrees, and at night, it's completely black."

From his home in the southern coastal city of Albany, Western Australia, Mr Nagrani has made it his mission to educate people on what he calls the "spectrum of blindness".

"I think people have this misconception that if you're blind, your eyes don't look normal," he said.

"I can still make eye contact because I can still see a little bit, so people get a little confused."

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When meeting new people, Mr Nagrani said he often felthe hadto "convince"them of his disability.

"I feel a sense of fear until I've convinced them that I have a disabilitybecause I don't want to be called a fraud.

"That is the fearthat people are going to say, 'His eyes look normal, he's making eye contact, I think he's faking it'."

Knowing there would come a day when he would lose his sight, hedidn't let his diagnosis deter him from pursuing his dream career.

"Growing up, I knew I was going to go blind, but I didn't want to pick a career based on that I wanted to live my life and do something that I enjoy," he said.

"Being creative, I got into graphic design and filmmaking, and I did that for 14 years.

"I'm proud to say I had a really successful career in marketing that I had to give up because I can't use laptops or computers anymore."

With the knowledge and skills gained from his career, Mr Nagrani is putting them to use bycreating infographics and videos for social media using his smartphone.

"Growing up, I never saw any content that prepared me for what it is that I will or won't see," he said.

"Now, I'm using my graphic design skills while I still can to create resources that other people are using."

His Instagram account showcases a sense of humour that hasn't happened totally by chance.

"Social media is all about entertainment you can present serious information, within reason, in a fun manner.

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"Going by the responses that I get, it's actually the entertaining, informative posts that are most engagingbecause people actually stop and read and comment."

But not everyone on the internet has his positive energy.

"There's always that one person who has something nasty to say," he said.

"I remember putting up a post once where I showed people what it's like to wake up with retinitis pigmentosa one of the shots was on the balcony, showcasing the beautiful Albany landscape.

"Someone commented,'What a waste of such a beautiful view on someone like you'.

"I get those comments, but I actually think that's a reflection on them, and I brush it off."

Blind people experience an extra layer of difficulty navigating day-to-day life because of social stigma, according to eye expert Professor William Morgan.

Often patients put in a lot of effort to appear "normal".

"Many people will think they're just normal peopleand get irritated and annoyed if they bump into them, for example, or take longer to sit down on a busbecause they're having to feel their way around the seat," Professor Morgan, from the University of Western Australia and managing director of Lions Eye Institute in Perth, said.

"I do get those comments from patients actually; that they put an enormous amount of effort into nullifying the disability as much as possible."

Professor Morgan said services hadimproved dramatically for vision-impaired people in recent years, but there wasstill a way to go in regard to awareness.

"These people are putting a huge effort into mixing in society, and so increasing the tolerance [would help, as well as] an awareness of the different sorts of vision that you lose with these broad categories of diseases."

For Mr Nagrani, sharing his personal experience online is aboutfostering acceptance for all forms of blindness.

"It makes me so happy to see people from across the globe message me, asking me if they can share my posts to raise awareness," he said.

"I feel likeeven though I've had to give up my marketing career, I'm actually finding this more fruitful, in the sense that I feel like I'm really making a difference now."

ABC Great Southern will deliver a wrap of the week's news, stories and photos every Thursday. Sign up here.

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Vision impairment and blindness related to NCDs: Fong – FBC News

Thursday, August 11th, 2022

Permanent Secretary for Health, Doctor James Fong says this is why the Ministry is considering using eye screening tests to diagnose other underlying health problems.

Most cases of blindness and vision impairment in the country stem from non-communicable diseases.

Permanent Secretary for Health, Doctor James Fong says this is why the Ministry is considering using eye screening tests to diagnose other underlying health problems.

There is a lot of undiagnosed NCDs around and what is most unfortunate is that many of those NCDs only become visible only when a person starts to lose their sight. I am hoping that we do not have to pick up diseases at that point, that there is some degree of screening of the eye, we will be able to early detect impairment and do something about it.

Dr Fong says blinding NCDs such as cataract, glaucoma and diabetic retinopathy are the most common eye diseases in the country.

He adds 80 percent of blindness and vision impairment is preventable or treatable, depending on early detection.

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Strategic blindness of caretaker government – The Jewish Star

Thursday, August 11th, 2022

By Caroline Glick

Operation Breaking Dawn was a textbook illustration of Israels tactical brilliance and prowess on the one hand, and strategic blindness on the other.

Tactically, Israels Iron Dome system allows its civilians to remain almost entirely unharmed while terror armies pummel Israels cities and villages with missiles and rockets. So too, Israel has developed precision-guided weapons and operational intelligence capabilities which in combination enable it to conduct pinpoint assaults against targets and destroy them with little to no collateral damage.

From Friday through Sunday, Islamic Jihad shot nearly a thousand projectiles at Israel. But largely thanks to Iron Dome, no Israelis were harmed by direct hits. In precision strikes, Israel was able to eliminate Islamic Jihads commanders.

However, while Israels leaders are right to trumpet the operations tactical, technology-based success, Operation Breaking Dawn was a strategic fiasco on multiple levels.

The first level of strategic failure is the operational one. Breaking Dawn was precipitated by Islamic Jihads decision to respond to Israels arrest of its senior operative Bassem Saadi early last week in Jenin with a threat to carry out a mass casualty attack on Israeli civilians and military personnel from Gaza.

According to Egyptian mediators, Israel agreed to consider releasing Saadi and perhaps another Islamic Jihad terrorist in exchange for a ceasefire. If the Egyptian announcement is accurate, then Islamic Jihad will be able to present its missile assault as a victory. By lobbing a thousand projectiles at Israeli cities from Gaza, the terror group was able to coerce Israel into freeing terrorists in Samaria.

Even better, from Islamic Jihads perspective, for the four days that preceded Israels initiation of Operation Breaking Dawn, the government ordered more than a million Israelis to remain in their homes and closed rail service and the major highways connecting population centers in southern Israel to the rest of the country. That four-day lockdown, based solely on Islamic Jihad threats, was the greatest victory the terror group ever achieved.

Israels operation demonstrated the depth of the strategic challenge Gaza poses. Islamic Jihad is a wholly owned subsidiary of Irans Revolutionary Guards Corps, which founded it in 1988 and still arms and commands its operations today.

Islamic Jihad used to be seen as a mere nuisance in the Gaza Strip. But this week it showed it has amassed an arsenal capable of presenting Israel with a massive security challenge. Even worse, it has just a fraction of the capabilities that Hamas enjoys.

Hamas is not a wholly owned subsidiary of Iran, but it is an Iranian client. Hamas receives funding and arms from Tehran. Its leaders are in direct, intimate contact with the Iranian regime, which they brag about. Hamas chief Ismail Haniyeh was in Tehran last April to participate in Iranian President Ebrahim Raisis inauguration. Hamas tens of thousands of missiles cover nearly all of Israel. Its anti-aircraft and anti-tank missiles pose a threat to Israeli ground and air operations in Gaza.

Iranian sponsorship isnt the only thing Hamas and Islamic Jihad share. They are partners. According to media reports, there were Hamas officers in Islamic Jihad command centers all week long. Hamas approved every missile volley Islamic Jihad launched, and provided it with logistical support. Given the intimacy of their cooperation, the fact that Hamas didnt use its own missiles to attack Israel is a meaningless distinction.

Indeed, its worse than that. Pretending that Hamas is not involved in an operation it actually enabled and participated in gives Hamas a free pass for waging war.

But for the Lapid-Gantz caretaker government, none of this mattered. The government and its attendant media insisted Hamas and Islamic Jihad are totally separate from one another, and even rivals. The governments narrative claimed Hamas was acting like a responsible adult.

Between Friday and Saturday, the IDFs job quickly moved from attacking Islamic Jihad to ending the operation as quickly as possible to avoid Palestinian civilian casualties that would compel Hamas to start shooting its own missiles at Israel.

In other words, the government put the onus on itself. Hamas would come in if Israel made a mistake. Hamas is responsible. It cares about its people. And it will only join the fray if Israel forces its hand.

This false narrative is doubly destructive given Hamas actual nature. Hamas isnt a responsible governing authority. Its a terrorist organization ideologically committed to annihilating Israel and the entire Jewish people. By treating Hamas as the responsible adult in the room, the government gave legitimacy to an actor that is morally, militarily, ideologically and politically illegitimate.

This is not to say that Israel should have opened a major campaign against Hamas. A caretaker government lacks the political legitimacy to initiate a large-scale conflict. But the governments kowtowing to Hamas, like its anxious acceptance of Islamic Jihads ceasefire terms, was unnecessary and destructive.

Caretaker Prime Minister Yair Lapid and Defense Minister Benny Gantzs behavior vis--vis Gaza is in keeping with the overall strategic blindness that has afflicted this government in relation not only to Irans Palestinian proxies Islamic Jihad and Hamas, but also Irans Lebanese legion Hezbollah and, indeed, Iran itself.

Lapid and Gantz are poised to accept a deal to transfer some of Israels sovereign economic waters to Lebanon. There are two concepts behind the deal, negotiated by the Biden administration.

First, most importantly and like the White House, Lapid and Gantz insist Lebanon is a political entity separate from Hezbollah. This is entirely false. Hezbollah is the most powerful military organization in Lebanon. It has swallowed the Lebanese Armed Forces, which operate at Hezbollahs pleasure. And it has also swallowed the government, which will not do anything Hezbollah opposes.

The second concept, which flows from the first, is that by enabling Lebanon to develop natural gas fields in the eastern Mediterranean, Israel will empower the government against Hezbollah. This too is entirely false. Hezbollah controls the negotiations. Lebanon will not profit from the deal at Hezbollahs expense. The deal will transform Hezbollah and Iran into players in the Mediterranean gas industry, opening up a whole new sphere of profit, as well as potential extortion and blackmail of Israel.

As for Iran itself, from the moment they formed their government with their erstwhile partner Alternate Prime Minister Naftali Bennett, Lapid and Gantz opted to subordinate Israels policies towards Iran to the Biden administration. They announced a policy of no surprises, which effectively gave the administration veto power over all Israeli operations against Irans nuclear installations and other offensive operations.

Since the Biden administrations central Middle East policy is to reinstate Barack Obamas 2015 nuclear deal with Iran, the implication of no surprises is that Israel agreed to subordinate its confrontational policy towards Iran to the US policy of appeasing Iran.

Lapid/Gantzs predecessor and nemesis is opposition leader Benjamin Netanyahu. During his long premiership, Netanyahu also sought to avoid major military confrontations with Hamas and Hezbollah. But unlike Lapid and Gantz, Netanyahu did so while adhering to a strategic concept that had the virtue of not only being right, but effective.

Netanyahu recognized that the Palestinians, like Hezbollah, are part of Irans war machine. As Iranian Revolutionary Guard Corps General Asghar Emami said in a May 2021 interview, Iran doesnt need to directly attack Israel because its proxies Hezbollah, Islamic Jihad and Hamas are on Israels borders.

Emami said, Due to our presence in the axis of resistance, we have placed [Israel] under siege. We dont need to send airplanes or missiles to Israel. Now, with our presence in the axis of resistance, we can hit Israel with mortar shells.

Netanyahu adopted an integrated, three-pronged Iran strategy. He sought to deprive Iran of funds to diminish its economic capacity to fund its proxies. He built and used the capacity to carry out near-continuous acts of sabotage against Irans nuclear installations and personnel. And he led Israel in waging a full-scale diplomatic war against Iran.

One of the crowning achievements of Netanyahus strategy was his success in persuading then-president Donald Trump to withdraw from Obamas 2015 deal with Iran. Obamas deal transferred more than $100 billion to Tehran through sanctions relief.

Immediately after the deal went into effect in August 2015, Iran began funneling massive funds to Hamas, Islamic Jihad and Hezbollah, as well as the Houthis in Yemen, enabling them to escalate their wars against Israel and the Sunni states. By walking away from the deal and reinstating US economic sanctions on Iran, Trump set Iran on the road to poverty, and its funding for its terror proxies dried up. Had the policy been continued under Biden, Islamic Jihad would likely not have had a thousand missiles of varying ranges to lob at Israel over three days.

Iran crossed the nuclear threshold in recent weeks for two reasons: First, the Biden administration stopped enforcing sanctions and thus emboldened the Iranians to massively increase their levels of uranium enrichment and stockpiles of enriched uranium. Second, Israel dramatically scaled back its operations in Iran as part of the Lapid-Gantz-Bennett no surprises policy.

Netanyahus diplomatic war against Iran, even in the face of US animosity, is what drew the Arab states to Israel.

The 2015 nuclear deal threatened the Sunnis no less than it threatened Israel. Netanyahus unapologetic opposition to the agreement drew Saudi Arabia, the UAE, Egypt and Bahrain to Israels side.

As for the Palestinians, Netanyahu largely ignored them. And when he was forced to fight them, he made clear that they were first and foremost Iranian proxies. His argument was convincing, because it was accurate.

In 2014, recognizing the truth of Netanyahus claim, the UAE, Saudi Arabia and Egypt stood with Israel against Hamas, Turkey, Qatar and the Obama administration, which tried to force Israel to accept Hamas ceasefire demands.

Over the past week, Lapid and Gantz barely mentioned Iran, despite the fact that Islamic Jihads leader Ziad Nahalka was in Tehran the entire time. Their reticence was likely due to the fact that as Irans Palestinian proxy pummeled Israel with missiles and rockets, Bidens negotiators were in Vienna, yet again begging Iran to accept sanctions relief in exchange for a nod to the 2015 nuclear deal.

By hiding the fact that Iran stood behind Islamic Jihad/Hamas entire assault, Gantz and Lapid returned the Palestinians to center stage, to devastating effect for Israel.

By giving Iran a free pass, Israel alienated its Arab allies. Instead of supporting Israel, the UAE is co-sponsoring a UN Security Council meeting to discuss Israels operation. Saudi Arabia published a full-throated condemnation of Israels operation against an Iranian proxy.

It is easy to understand the logic of a limited campaign. But by carrying it out in a state of strategic blindness, the caretaker government legitimized Hamas and undermined Israels position in the strategic battle of our times against Iran.

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Strategic blindness of caretaker government - The Jewish Star

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Massachusetts woman blinded by attack working to help others regain sight – WCVB Boston

Thursday, August 11th, 2022

The victim of a gruesome attack in Massachusetts is trying to turn her suffering into something good.Janet Blanchard, of Haverhill, was left blind and almost died from a random attack in her hometown last year.NewsCenter 5's Maria Stephanos lived next door to Blanchard when they were growing up in Groveland, and Stephanos shared Blanchard's story following the attack.Blanchard is now focused on spending time with her family and friends, especially her 14-month-old grandson, Lincoln.She is still searching for a cure for her blindness and working to help others who suffer from complete vision loss.On Sept. 2, the Bradford Country Club in Haverhill will host the Janet's Journey Golf Tournament, a fundraiser for the Second Chance for Sight Foundation a nonprofit that was founded in Blanchard's honor by her son-in-law, Zach.The money raised by the golf tournament will help assist complete-vision-loss organizations, medical research and individuals. Blanchard and her family hope to help others who have been affected by blindness by improving their quality of life through research and development.Anyone who is interested in donating to the Second Chance for Sight Foundation should email Leadership@secondchanceforsight.com.Those who are interested in sponsoring the Janet's Journey Golf Tournament should click here for more information.

The victim of a gruesome attack in Massachusetts is trying to turn her suffering into something good.

Janet Blanchard, of Haverhill, was left blind and almost died from a random attack in her hometown last year.

NewsCenter 5's Maria Stephanos lived next door to Blanchard when they were growing up in Groveland, and Stephanos shared Blanchard's story following the attack.

Blanchard is now focused on spending time with her family and friends, especially her 14-month-old grandson, Lincoln.

She is still searching for a cure for her blindness and working to help others who suffer from complete vision loss.

On Sept. 2, the Bradford Country Club in Haverhill will host the Janet's Journey Golf Tournament, a fundraiser for the Second Chance for Sight Foundation a nonprofit that was founded in Blanchard's honor by her son-in-law, Zach.

The money raised by the golf tournament will help assist complete-vision-loss organizations, medical research and individuals. Blanchard and her family hope to help others who have been affected by blindness by improving their quality of life through research and development.

Anyone who is interested in donating to the Second Chance for Sight Foundation should email Leadership@secondchanceforsight.com.

Those who are interested in sponsoring the Janet's Journey Golf Tournament should click here for more information.

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Massachusetts woman blinded by attack working to help others regain sight - WCVB Boston

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Persuasion Film Review: Is Heterogeneous Casting Race-Inclusionary Or Escapist? – Feminism In India

Thursday, August 11th, 2022

Its 2022, and the modernisation project of the regency era is well underway. Each year, a new season ofBridgertondescends upon us and gives the internet a new diamond of the season to rave over. If 2021 was Reg-Jean Pages year, 2022 would be Simone Ashleys. Not only are the two protagonists in theGossip Girl-Esque period drama, but both stand out as actors of colour in a conventionally white story.

A more recent case of colour-blind casting in regency-era dramas has been in the case of the Netflix adaptation of Jane AustensPersuasion. With Malaysian-British actor Henry Golding, Nigerian-British actress Nikki Amuka-Bird, and many more, Persuasion joins the race-blind casting club.

Within the casting itself, critics point out that race-blindness has compromised historical accuracy. As in the case of most race-blind period dramas, this argument has also been extended to instances such as the questions of accuracyregardingHalle Baileys casting inThe Little Mermaid(2023).

However, such casting in historical dramas is not a new phenomenon. Be it Dev PatelplayingDavid Copperfield(2019) and Adeel AkhtarplayingLestrade inEnola Holmes(2020), colour-bind casting has been a feature in showbiz for quite some time. In fact, lest we forget, even Amitabh BachchanplayedMeyer Wolfsheim inThe Great Gatsby(2013), a character is originally written to be an Ashkenazi Jew.

Disney-fantasy films such as the upcomingLittle Mermaid(2023) and superhero movies likeThor: Ragnarok(2017) have also embraced a colour-blind cast. So if the colour-blind casting is so rapidly expanding to all forms of film and television, what is with the whole debate over it?

It all began with the operaTannhuser(1961), whichfeaturedmezzo-soprano Grace Bumbry as Venus. Bumbry led on to become the first black singer to ever perform at the Bayreuth Festival in Germany. However, her casting was not just a move to make the opera seem more inclusive, but in fact, there lay a much deeper vision on the part of the director Wieland Wagner. Hiring a black singer for a white role waspartof a larger picture to sever post-War Bayreuths ties from its turbulent and racist past.

Opponents of heterogeneous casting in implausible roles and plotlines have also alleged that racial inclusion has been reduced to atick-box exercise. Race-blindness solely for the purpose of scoring DEI (Diversity, Equity, and Inclusion) points is increasingly common and a lot less desirable.

The opera soon became a huge scandal, and Bumbrys casting swelled up to a high level of national significance. Contrast this with the deluge of critical views thatPersuasionfinds itself in. Leaving the casting aside the screenplay itself is facing a lot of flak- especially from Austens deepest admirers, who regard the movie to be a greatly watered-down andFleabag-ifiedversion of the novel.

Within the casting itself, critics point out that race blindness has compromised historical accuracy. As in the case of most race-blind period dramas, this argument has also been extended to instances such as the questions of accuracyregardingHalle Baileys casting inThe Little Mermaid(2023).

Opponents of heterogeneous casting in implausible roles and plotlines have also alleged that racial inclusion has been reduced to atick-box exercise. Race-blindness solely for the purpose of scoring DEI (Diversity, Equity, and Inclusion) points is increasingly common and a lot less desirable.

As in the case of the 2020 Huluadaptationof Sally Rooneys novel Normal People, thoughtless race-blind casting led to the three major anti-heroes being people of colour for no specific reason. Colour-conscious casting in modern fiction would rather focus on racial diversity by answering why a specific character needs to belong to a specific race.

As in the case of the 2020 Huluadaptationof Sally Rooneys novel Normal People, thoughtless race-blind casting led to the three major anti-heroes being people of colour for no specific reason. Colour-conscious casting in modern fiction would rather focus on racial diversity by answering why a specific character needs to belong to a specific race.

This, in turn, would require self-interrogation and accountability, which could be the factors that filmmakers try to avoid by random race-blind casting.

The damages that can be done by race-blind casting are deeper. At best, it is implausible and almost hilarious to see a host of actors from various racial backgrounds play characters from theMahabharatain the 1989 film adaptation, written by English and French screenwriters. At worst, it ignores the history of discrimination in the entertainment industry and dismisses any accountability about the intention of why an actor of a specific race was cast for a specific role.

A 2018articlein the Harvard Journal of Sports and Entertainment Law addresses another facet of race-blind casting in Hollywood. Race-blind casting does not appropriately deal with the discriminatory environment that exists even in the present-day labour market. Ignoring race, as done inPersuasionandBridgerton, feeds into the harmful notion that not talking about race and the contexts it adds would fix Americas deeply entrenched racist rhetoric.

Movies and TV have great potential to contribute to meaningful societal changes, learning about the world, understanding diverse contexts, and connecting with various cultures.

However, a very elementary and widely-observed purpose of cinema is entertainment and even escapism. For instance, most mainstream Hindi cinema is aimed at being anescapistexperience for the masses, providing a brief distraction from the trials and tribulations that the lower and middle classes face.

Along these lines, proponents of race-blind casting argue that people of colour, too, deserve escapist, fantastical, and implausible storylines in mainstream cinema. Addressing historical oppression and marginalisation in each story with a character of colour would not only take the focus away from the primary plotline but also restrict people of colour to only see themselves represented through reminders of a painful past and present.

Also read:Women, Race & Class: Angela Davis And The Womens Movement In India

What acts as a middle ground on both sides of this debate is the need to replace colour-blind casting with colour-conscious casting. While the former succeeded in bringing in a larger number of actors of colour to our screens, the latteracknowledgesand embraces the various layers and dimensions that racial contexts bring to a story.

In order to meaningfully and accurately include characters of colour in historical dramas, it is essential, to begin with choosing a racially diverse historical setting in the first place. Such a plotline can act as the perfect vehicle to not only address issues of racial representation in traditionally white-dominant storylines, but it would also provide depth to the story by appropriately weaving in conversations on race within backgrounds they have been missing in all this time.

Not seeing colour and being colour-blind has always been ineffective and even harmful response to tackling deeply-rooted racism. Duplicating the same within film and TV would not have any different effects either. Heres hoping that whichever upcoming period drama is going to be the next talk-of-the-town, it does away with the pattern of feeding viewers false and one-dimensionalhistoriesunder the garb of representation.

Also read:A Racist India & How Its Racism Is Different For North-Eastern Women

Featured image source:British GQ

Excerpt from:
Persuasion Film Review: Is Heterogeneous Casting Race-Inclusionary Or Escapist? - Feminism In India

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Is It Time To Start Using Race And Gender To Combat Bias In Lending? – Forbes

Thursday, August 11th, 2022

Trying to achieve fairness through blindness has not worked.

A woman, lets call her Lisa, applies for a loan. Shes 35 with a graduate degree, a high earning trajectory and a 670 credit score. She also just returned to work after taking time off to start a family.

Her application goes to an algorithm, which assesses her risk profile to determine whether she should be approved. The algorithm sees her recent gap in employment and labels her a risky borrower. The result? Her application is rejected.

Examples like this happen every day in lending. Are these decisions fair?

When it comes to fairness in lending, a cardinal rule is, Thou shalt not use variables like race, gender or age when deciding whether to approve someone for a loan.

This rule dates back to the Equal Credit Opportunity Act (ECOA), passed in 1974 to stop lenders from deliberately denying loans to Black applicants and segregating neighborhoodsa practice called redlining. The problem got so bad, the government had to ban the consideration of race or gender when making loan approval or other high-stakes decisions.

The assumption behind ECOA was that if decision makersbe they humans or machinesare unaware of attributes like race or gender at decision-time, then the actions they take will be based on neutral and objective factors that are fair.

Theres just one problem with this assumption: Its wishful thinking to assume that keeping algorithms blind to protected characteristics means the algorithms wont discriminate.

In fact, building models that are blind to protected status information may reinforce pre-existing biases in the data. As legal scholar Pauline Kim observed:

Simply blinding a model to sensitive characteristics like race or sex will not prevent these tools from having discriminatory effects. Not only can biased outcomes still occur, but discarding demographic information makes bias harder to detect, and, in some cases, could make it worse.

In a credit market where Black applicants are often denied at twice the rate of White applicants and pay higher interest rates despite strong credit performance, the time has come to admit that Fairness Through Blindness in lending has failed.

If we want to improve access to credit for historically underrepresented groups, maybe we need to try something different: Fairness Through Awareness, where race, gender and other protected information is available during model training to shape the resulting models to be fairer.

Why will Fairness Through Awareness work better?

Consider the example of the woman, Lisa, above.

Many underwriting models look for consistent employment as a sign of creditworthiness: the longer youve been working without a gap, the thinking goes, the more creditworthy you are. But if Lisa takes time out of the workforce to start a family, lending models that weigh consistent employment as a strong criterion will rank her as less creditworthy (all other things being equal) than a man who worked through that period.

The result is that Lisa will have a higher chance of being rejected, or approved on worse terms, even if shes demonstrated in other ways that shes just as creditworthy as a similar male applicant.

Models that make use of protected data during training can prevent this outcome in ways that race and gender blind models cannot. If we train AI models to understand that they will encounter a population of applicants called women, and that women are likely to take time off from the workforce, the model will know in production that someone who takes time off shouldnt necessarily be deemed riskier.

Simply put, different people and groups behave differently. And those differences may not make members of one group less creditworthy than members of another.

If we give algorithms the right data during training, we can teach them more about these differences. This new data helps the model evaluate variables like consistent employment in context, and with greater awareness of how to make fairer decisions.

Fairness Through Awareness techniques are showing impressive results in healthcare, where identity-aligned algorithms tailored to specific patient populations are driving better clinical outcomes for underserved groups.

Lenders using Fairness Through Awareness modeling techniques have also reported encouraging results.

In a 2020 study, researchers trained a credit model using information about gender. The gender-specific model resulted in about 80% of women getting higher credit scores than the gender-blind model.

Another study, done by my co-founder John Merrill, found that an installment lender could safely increase its approval rate by 10% while also increasing its fairness (measured in terms of adverse impact ratio) to Black applicants by 16%.

The law does not prohibit using data like gender and race during model trainingthough regulators have never given explicit guidance on the matter. For years lenders have used some consciousness of protected status to avoid discrimination by, say, lowering a credit score approval threshold from 700 to 695 if doing so results in a more demographically balanced portfolio. In addition, using protected status information is expressly permitted to test models for disparate impact and search for less discriminatory alternatives.

Granted, allowing protected data in credit modeling carries some risk. It is illegal to use protected data at decision time, and when lenders are in possession of any protected status information theres the chance that this data will inappropriately influence a lenders decisions.

As such, Fairness Through Awareness techniques in model development require safeguards that limit use and preserve privacy. Protected data can be anonymized or encrypted, access to it can be managed by third party specialists, and algorithms can be designed to maximize both fairness and privacy.

Fairness Through Blindness has created a delusion that the disparities in American lending are attributable to neutral factors found in a credit report. But studies show again and again that protected status information, if used responsibly, can dramatically increase positive outcomes for historically disadvantaged groups at acceptable levels of risk.

Weve tried to achieve fairness in lending through blindness. It hasnt worked. Now its time to try Fairness Through Awareness, before the current disparities in American lending become a self-fulfilling prophecy.

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Is It Time To Start Using Race And Gender To Combat Bias In Lending? - Forbes

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The journey of Kali Yugi started with the mistake of objectives! – Youthistaan

Thursday, August 11th, 2022

The Hindus concept of Satyug vs Kaliyug is actually on the difference of free-self-respecting life versus dependent-bonded slavery period. fearless vs fearful mood, intelligence vs blindness, There is a difference in the time of Karmavaad vs. Fatalism. that is when India became independent in 1947 So India had to make that constitution which would change the mood of the Hindus, He was worried about his behavior. The question is, what should have been the objectives of independent India and its constitution? My The straight forward answer is that the first priority of the nation-state of India is to end the Kali Yuga of the Hindus. Citizens out of the experience of fourteen hundred years of slavery. Fear, Liberation of the people from the systems of hunger and loot.

India of seventy five Kaliyuga decreased or increased,,2 : The issue is complex. I have analyzed the Hindu character in the past as well. The Hindu nature created in the slavery of fourteen hundred years has already been discussed. The essence is that the concept of Satyug versus Kaliyug of the Hindu is actually on the difference of free-self-respecting life versus dependent-bonded slavery period. There is a difference between fearless versus fearful mood, intelligence versus blindness, karmavad versus fatalism. We all know why Kali Yuga was formed for Hindus and what are its symptoms. Because of that, when India became independent in 1947, India had to make a constitution in which the change of mood of the Hindus, their behavior and behavior would have been concerned.

The question is, what should have been the objectives of independent India and its constitution? Its straight forward answer is that the first priority of the nation-state of India is to end the Kali Yuga of the Hindus. The citizens came out from the experience of fourteen hundred years of slavery. Liberation of the people from the systems of fear, hunger and loot.

Only then the constitution had to adopt the resolutions of these three tasks, objectives (1) To eliminate the fear of governance, governance among the citizens. So that people get out of the mood of slavery and have the nature to live with vivacity. So that they (2) be free from the habit of fear, devotion, hunger and dependent life created in the experience of subordination. Citizens left the escapist-fatalistic nature and became puritan-karmicists. (3) To embrace these two objectives in the mind of the country, importance should have been given to the knowledge sources, energy and sense of Sanatani Dharma-Shastras. So that the ideals of the character-moral-cultural values would form and blossom the resolve of the Hindu majority community. In the education-understanding of the citizens, that intellectual force would have been made possible by which the renaissance of the eternal heritage of ancient civilization-culture would have been possible. The unique identity of India could have been created by the eternal intellectual force. The global contribution of Hindus would have been possible.

Think, in seventy-five years from the Constitution of India, its results and the behavior of the nation, what identity of India has developed in the world? Is there such an identity that has been created in the last 75 years of other constitutions like Japan, Germany, Israel, China made around the time of 1947. Japan, Germany, Israel, and China all have their own distinctive identities of culture and culture. He has a status in his world fraternity. Think what is the identity of India in the world ahead of them?

stupid superstition

The objectives of ending Kali Yuga were not laid down in the Constitution of India. Rather, the Kali-yuga nature of the people, the official methods of slavery were made more powerful. The above mentioned three did not work. The Constituent Assembly of India did not consider it necessary to refine the merits and demerits of Hindu mood-disposition, intellect and education, nor did it make it the purpose of molding the civil rites into the moral parameters of religion-culture!

As a result, in a crowded civil society without culture, without character, labor is done like donkeys, but the result is poverty, vanity, wildness, living in cages, tying and sharing in caste-religion. Pay attention to the current times. What kind of India photos have been found in the world? What news was heard from India in the global concerns of the pandemic? The world has seen photos of India like cremation grounds and unclaimed deaths on the banks of the Ganges, in the same way, symbols of any other civilization-culture were seen in the country? What superstitious things the world has heard and known from India. Like the diagnosis of virus with cow dung. To drive away the epidemic by clapping. Means the scriptures of the past (there is no such thing in any Satyug Sanatani theology) and not by knowledge, but by cooking up the superstitions of myths, the Hindu was proved to be a foolish nature. In the myths itself, the Prime Minister of India talks about organ transplant surgery in ancient India and the devotees shout that the solution to every disease and problem is the mantra. Cow urine cures diseases and cow releases oxygen. Not only this, the peacock pregnant with the tears of the peacock and leaving the duck in the pond created oxygen in the water of the pond. Whatsup foolishness is the identity of India. An IIT head from India releases the video that the father of a friend of his in Chennai was captured by a ghost and he chased away the ghost by reciting the Bhagavad Gita. Imagine, a robotics professor and his skull telling the world that his friends father was physically very weak but after reciting the mantra, he got such power that he got up and started dancing. Later, the friends mother and wife were also caught by the ghost. Then he recited the mantra loudly for 45 minutes to an hour and freed both of them from the ghost.

Is all this the nectar of knowledge of India for 75 years? Know that the Sanatani Hindu did not live in such superstitions. Such straw is not in the Vedas of Hindus. On the contrary, the Adi Sanatani Dharmashastras of the Hindu were composing the Vedas and Vedangas by understanding nature, revealing and invoking its powers. There was debate with Ilham then.

In fact, this mental disability of India is the Kali-yuga nature of the time of slavery. The subjection of the heretics has made us fatalists-superstitions. That is why the Hindu elite leaders before and after independence had to seriously consider the reality of mental handicap. Had to find a solution. In its truth it was to become the primary objective of the Constitution. But the opposite happened. There was a superstition among the gentry of the Constituent Assembly that there is no such idea of political philosophy, polity in Hindu religion-civilization-culture, so that the citizens of the concept of nation-state can make themselves cultured and responsible. It was also thought that if the values of culture-religion or its insistence on the constitution-country were prestige, then the state religion should not be considered biased. We the people of India will be called antiquarians. Such fear and superstition apparently stemmed from the dreadful mood of the slavery period. Gandhi continued to see the ideal of Ram Rajya but his followers, the Constituent Assembly, rejected the truthful light of Ram Rajya and the original Sanatani religion behind it in horror and cynicism that religion and theology were opium and gapaudi!

As a result, the constitution was formed only which was the already made fabric of the Britishs language, philosophy, thought, intention, the tendency to rule the people. The making of the constitution did not take place in the priority of giving sovereign wings to the individuals freedom, his self-ownership, charitableness, but was building democracy in the stamp of making sovereignty-monarchy of power and government.

The result is in front. Seventy-five years later, Hindus (be it secular or communal) are fighting fiercely for their freedom. He lives in hunger, fear and devotion. He is filling his stomach with donations, donations, freebies. One gets rich from corruption. And when it comes to human nature, it is superstitious, brazen and scattered.

am i wrong? (Ongoing)

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The journey of Kali Yugi started with the mistake of objectives! - Youthistaan

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