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Archive for the ‘Longevity Genetics’ Category

Losing hair fast? Applying this natural solution to the scalp resulted in new hair growth – Express

Monday, September 28th, 2020

Hair loss can be the result of complex environmental and genetic processes. In the former camp lies responses to stressful situations and certain cancer treatments. In the genetic camp is androgenetic alopecia - commonly known as pattern baldness. It usually runs in the family, which, on the face of it, seems dispiriting.

Fighting genetics may seem like a losing battle but evidence does suggest you can reverse this form of hair loss.

One strategy that has yielded surprising results is applying a melatonin solution to the scalp.

Most people will associate melatonin with sleep - the hormone plays a central role in the bodys sleep-wake cycle.

As the National Sleep Foundation explains, its production increases with evening darkness, promoting healthy sleep and helping to orient our circadian rhythm.

READ MORE:Hair loss treatment - Dr Sara explains the best type of shampoo to stimulate hair growth

Circadian rhythms are 24-hour cycles that are part of the bodys internal clock, governing important processes such as the sleep-wake cycle.

Theres evidence that the benefits of melatonin extend to treating hair loss.

This is because melatonin also affects hair growth, as the hair growth cycle in mammals is under circadian control, according to The Lifespan Research Institute, a research body that focuses on anti-ageing compounds.

"As with other circadian cycles, the hair growth cycle becomes dysregulated and lower in amplitude with age," explains the research body.

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In a randomised double-blind study of 40 women with hair loss, melatonin solution applied to the scalp increased hair growth significantly relative to placebo.

What's more, in a study published in the International journal of trichology, 1891 male and female patients with androgenic alopecia applied a topical melatonin solution for three months.

At three months 61 percent of patients had no hair loss, compared to 12.2 percent at the start; 22 percent had new hair growth at three months compared to four percent at baseline.

The incidence of seborrheic dermatitis also declined, from 34.5 percent at baseline to 9.9 percent at three months.

Seborrheic (seb-o-REE-ik) dermatitis is a common skin condition that mainly affects your scalp.

The skin condition can cause an itchy, flaky rash, which may lead to hair loss due to excessive itching.

According to the NHS, finasteride and minoxidil are the main treatments for male pattern baldness.

"Minoxidil can also be used to treat female pattern baldness. Women shouldn't use finasteride," explains the NHS.

There are a number of drawbacks to consider before taking these treatments.

According to the NHS, these treatments:

These treatments:

Alternatively, some wigs are available on the NHS, but you may have to pay unless you qualify for financial help.

While considering your options, you may benefit from some psychological support.

Your GP may be able to help you get some counselling or you can join a support group, adds the NHS.

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Losing hair fast? Applying this natural solution to the scalp resulted in new hair growth - Express

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Lenny Kravitz on His Signature Scent, His Beach Beauty Routine, and the Secret to His Longevity – Vogue

Thursday, September 24th, 2020

Before lockdown began in March, Lenny Kravitz packed a bag for a week and headed to his home in Eleuthera in the Bahamas. His stay ended up being much longer than that. The singer and guitarist has spent the last six and a half months on the island he loves, returning to his Bahamian roots and living off the land. Save for a bottle of YSL Beautys Y eau de parfum, that is. As the newand lets face it, entirely fittingface of the French fashion houses seductive fougre scent, its become his signature.

Its fresh, its clean, its got spice, says Kravitz of Y, which opens with sparkling notes of green apple and bergamot, with a heart of lavender and geranium thats warmed by a zing of lemony ginger. During this period of being here on this island and living very simplybeing in the ocean, in the sun, and in the bush, as we call itit just fits. The art of presentation has always been a force within Kravitzs life, and like many during these challenging times, hes looked to his choice fragrance to elevate his mood. Im only around a few people and have no social functions, but some days I just need a little lift, explains Kravitz. I put on a nice shirt, and Ill spray on some fragrance, and it just makes me feel better. You dont have to do it for somebody, something, or some function. You can just do it for yourself.

Sticking to whats tried-and-true, Kravitz has been rotating between his rock-and-roll wardrobe signaturesdenim button-downs, love-worn ripped jeans, and printed skinny scarvesas well as following a streamlined beauty routine. The things that I use on my body are the same that Ive always used, he says, rattling off a list of natural oils and butters, including coconut oil, shea butter, and cocoa butter, as well as Dr. Bronners Almond Pure-Castile Liquid Soap, adding, I wash my body in it. I wash my hair with it. I washed my clothes in it. In his haven of the Caribbean, hes also been enjoying the spoilsand skin-care benefitsof the beach, the pearlescent white sand in particular. We have the most beautiful sand here in the Bahamasits very, very, very powdery, very, very fine, he explains. So when Im in the ocean, and I want to scrub my body, I use the sand. Thats what going on over here.

Besides the kind of head-to-toe exfoliation only a one-way ticket to Eleuthera can buy, Kravitz has been staying well, mind and body, by tending to his garden, cooking his own meals, and juicing with daily shots of immunity-boosting ginger. And hes been feeding off the island for his daily workout, an hour-long bike ride, as well. Thats been my form of cardio that I enjoy the most here, rather than being on a treadmill, he says. Its getting out in the sun and riding on the road with a lot of it on the ocean. Its so beautiful, and it gives you time to meditate. For mental clarity, hes also been limiting his news intake in an effort to tune out the noise. I only check the news and whats going on in the world often enough so that Im not in the dark, but Im not watching the television and inside of all of this negativity, he says. In terms of staying creative, Kravitz, who is working on his next album, is letting inspiration come to him in time. Its almost like if you have a radio receiver, and youre turning the dial, and all you hear is static until you finally hear music, he explains of his process. I prefer it that way because then its really pure. Im not involving my own ego or my own ideas or projections. Im getting what Im getting.

While Kravitz has always followed his own path doing what feels right to look and feel his best, he credits genetics and familial role models as the true secrets to his longevityand his impossibly ageless physique. My grandfather lived up into his 90s, and he had a thirst for life, for learning, for growing, and I think Ive inherited that from him, he explains. With the genes that I have from my parents and my grandparents, we dont seem to visibly age like one might think, so all of those things togetherwith, of course, taking care of yourself, putting the right things in your body, and taking care of your mind and spirithave contributed to aging just being about experiencing and living, not about falling apart.

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Lenny Kravitz on His Signature Scent, His Beach Beauty Routine, and the Secret to His Longevity - Vogue

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Healthy Aging Month observed nationwide in September – News – The Hutchinson News

Tuesday, September 22nd, 2020

September is Healthy Aging Month, an annual observance that deserves more attention this year as the nation deals with a pandemic unlike anything we have experienced for a century. Medical Author Dr. William W. Shiel, Jr. defines aging as the process of becoming older. Aging is not the same for any two people, due to factors including lifestyle, environment and family genetics. According to medical experts, the first signs of aging appears on the surface of the skin during the mid-20s.

More than 80,000 Americans are over the age of 100 and 20,000 have surpassed their 105th birthday, two statistics that continue to grow. Many remain active and live independently. Both major party candidates for president this year are more than 70 years of age.

Aging has been called the greatest known risk factor for most human diseases and can be either physical or psychological. Approximately 150,000 people die daily worldwide, two thirds of which are from age-related issues. Older adults and those who have underlying health conditions such as heart and lung issues and diabetes are at increased risk of severe illness, including COVID-19. Adults 65 years of age and older account for 16 percent of the nations population, but 80 percent of COVID-19 deaths claim this group of people.

The pandemic has resulted in increased stress in the lives of all Americans, and, in particular, those who are older or confined to home.

The effects of stress include:

Needless fear and worry about ones healthChanges in sleep or eating patternsDifficulty concentratingWorsening of chronic health problemsWorsening of mental health conditionsIncreased use of tobacco and/or alcohol

Stories regarding accomplishments of older Americans are more frequent these days and serve as encouragement for all. In 2014, 90-year-old Ernie Andrus walked, or as he said, "jogged" across America to honor the ship he served on during World War I. That same year, former President George H.W. Bush, to celebrate his 90th birthday, parachuted out of an airplane, smiling all the way to the ground, as his frightened family watched nearby.

Locally, Judge Wesley Brown, appointed a federal judge in 1962, served one-year shy of a half-century before passing away in 2011 at the age of 104. In an Associated Press interview on the year of his death, Judge Brown was asked to explain his longevity as a member of the federal judiciary, and his response was brief, to the point, and similar to his traditional courtroom demeanor. "As a federal judge, I was appointed for life or good behavior, whichever I lose first," Brown said. In a follow-up question, the reporter asked how he planned to exit the job, he said, "Feet first."

So, what advice can a healthcare professional possibly give to hearty souls to ensure they will continue healthy living, particularly in these unprecedented times? Keep masks, tissues, and hand sanitizer in your possession when venturing out. If possible, avoid others who are not wearing masks. Ask others around you to wear masks. Make certain your vaccinations and other preventive services are current, stay physically active and practice healthy habits to cope with stress. People of all ages who adhere to these precautionary measures will hasten the day when COVID-19 will be an event of the past. That day could not come any too soon.

Ken Johnson is President and CEO of Hutchinson Regional Healthcare System.

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Healthy Aging Month observed nationwide in September - News - The Hutchinson News

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How to Live Longer: A Look at the Science Behind the Longevity Movement – Vogue

Tuesday, September 22nd, 2020

If fasting is not exactly your speed, diet is still tremendously important. As for what you should eat, the gold standard remains the Mediterranean dietone that is high in vegetables, fruits, whole grains, beans, nuts, seeds, and olive oil, and low on red meatthe only diet, says Barzilai, proven by clinical research to decrease cardiovascular mortality. A recent study in the medical journal Gut found that following it for just one year slowed the development of age-related inflammatory processes.

David Sinclair, Ph.D., Harvard geneticist and author of the bestseller Lifespan: Why We Ageand Why We Dont Have To, says the Mediterranean diet essentially tricks the body into thinking weve been doing exercise and fasting. Of course, this is not a permission slip for bottomless bowls of rigatoni; too much of a good thing is too much. Dan Buettner, the National Geographic Fellow who helped popularize the idea of the blue zonesthe five areas worldwide with the longest-lived denizenssays he follows a rule practiced by the residents of Okinawa, Japan, and stops eating when his stomach is 80 percent full. And perhaps consider occasionally skipping dessert: Research shows that sugar intake accelerates age-related inflammation. The more sugar you eat, the faster you age, says Robert Lustig, professor of pediatric endocrinology at the University of California, San Francisco. (The American Heart Association recommends that women keep it under six teaspoons per day.)

Other crucial life practices: adequate sleep and stress management. In blue zones, says Buettner, people downshift all day long, through prayer, meditation, or just taking naps. And scientists are also coming to more fully understand the role that other people play in prolonging life. A 2019 study in the journal SSM-Population Health found that social relationships significantly increase life span in older adults. Neuroscientist Daniel Levitin, author of this years Successful Aging, has found that friendships at age 80 are a bigger predictor of health than cholesterol level. Friends and even neighbors, he writes, protect your brain, while loneliness has been implicated in just about every medical problem you can think of.

But what about the factors you cant control? Most of us dont know whats lurking in our genome and are not often aware we might inherit some disease until we see the symptoms. That is changing, with tests that are leagues beyond 23andMe. The new Preventive Genomics Clinic at Brigham and Womens Hospital in Boston is the first academic clinic in the country to offer comprehensive DNA sequencing and interpretation of nearly 6,000 disease-associated genes, ranging from common cancers to the rare Fabry disease, which impairs fat breakdown in cells and affects the heart. Roughly 20 percent of people will be carrying a variant for a rare disease, such as hereditary heart problems, says director Robert Green, M.D., medical geneticist at Brigham and Womens. Where a full panel of tests used to cost many hundreds of thousands of dollars, the clinic charges $250 for a smaller panel and $1,900 for full sequencing and interpretation. (These costs are not yet covered by most insurance.)

In the near future, says Barzilai as we finish our walk, we can be healthy and vital in our 90s and beyond. He laughs. It may sound like science fiction, but I promise you, its science. While I can comprehend the misgivings about prolonging life, Ill admit that Im still programmed to crave those extra years, and will adopt what changes I can to make them more vibrant. My role model here is Gloria Steinem, now 86. I plan to live to be 100, she once remarked. Which I would have to do anyway, just to meet my deadlines.

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How to Live Longer: A Look at the Science Behind the Longevity Movement - Vogue

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Massive Growth in Precision Medicine Software Market to Witness Robust Expansion by 2026 with Top Key Players like Syapse, Allscripts, Qiagen, Roper…

Tuesday, September 22nd, 2020

Precision Medicine Software Marketresearch report is the new statistical data source added byA2Z Market Research. It uses several approaches for analyzing the data of target market such as primary and secondary research methodologies. It includes investigations based on historical records, current statistics, and futuristic developments.

The report gives a thorough overview of the present growth dynamics of the global Precision Medicine Software with the help of vast market data covering all important aspects and market segments. The report gives a birds eye view of the past and present trends as well the factors expected to drive or impede the market growth prospects of the Precision Medicine Software market in the near future.

Precision Medicine Software Market is growing at a High CAGR during the forecast period 2020-2026. The increasing interest of the individuals in this industry is that the major reason for the expansion of this market.

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Top Key Players Profiled in this report are:

Syapse, Allscripts, Qiagen, Roper Technologies, Fabric Genomics, Foundation Medicine, Sophia Genetics, PierianDx, Human Longevity, Translational Software, Gene42, Lifeomic Health.

The key questions answered in this report:

Various factors are responsible for the markets growth trajectory, which are studied at length in the report. In addition, the report lists down the restraints that are posing threat to the global Precision Medicine Software market. It also gauges the bargaining power of suppliers and buyers, threat from new entrants and product substitute, and the degree of competition prevailing in the market. The influence of the latest government guidelines is also analyzed in detail in the report. It studies the Precision Medicine Software markets trajectory between forecast periods.

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The cost analysis of the Global Precision Medicine Software Market has been performed while keeping in view manufacturing expenses, labor cost, and raw materials and their market concentration rate, suppliers, and price trend. Other factors such as Supply chain, downstream buyers, and sourcing strategy have been assessed to provide a complete and in-depth view of the market. Buyers of the report will also be exposed to a study on market positioning with factors such as target client, brand strategy, and price strategy taken into consideration.

The report provides insights on the following pointers:

Market Penetration:Comprehensive information on the product portfolios of the top players in the Precision Medicine Software market.

Product Development/Innovation:Detailed insights on the upcoming technologies, R&D activities, and product launches in the market.

Competitive Assessment: In-depth assessment of the market strategies, geographic and business segments of the leading players in the market.

Market Development:Comprehensive information about emerging markets. This report analyzes the market for various segments across geographies.

Market Diversification:Exhaustive information about new products, untapped geographies, recent developments, and investments in the Precision Medicine Software market.

Table of Contents

Global Precision Medicine Software Market Research Report 2020 2026

Chapter 1 Precision Medicine Software Market Overview

Chapter 2 Global Economic Impact on Industry

Chapter 3 Global Market Competition by Manufacturers

Chapter 4 Global Production, Revenue (Value) by Region

Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6 Global Production, Revenue (Value), Price Trend by Type

Chapter 7 Global Market Analysis by Application

Chapter 8 Manufacturing Cost Analysis

Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10 Marketing Strategy Analysis, Distributors/Traders

Chapter 11 Market Effect Factors Analysis

Chapter 12 Global Precision Medicine Software Market Forecast

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Guest opinion: Why accessible health care is not government takeover – Deseret News

Tuesday, September 15th, 2020

I wish to counter many politicians claims that the government seeks to take over our health care system. The specious claims ignore the huge beneficial role government has played, and plays, in improving human health. Our collective good health and longevity derives from a hundred years of federally funded research in public health, human physiology, genetics, surgery, pharmacology, immunology, microbiology, virology and engineering.

Biomedical research at universities, medical schools, hospitals and research laboratories is substantially supported by the government. Few realize that the largest share of funds for training physicians and for postgraduate physician training come directly or indirectly from the government.

Millions of Americans receive health care through Medicare, Medicaid, veterans hospitals, Indian Health Service, Public Health Service, the Uniformed Services (Department of Defense) and others. The government subsidizes health care insurance premiums for thousands of United States civil servants. Without government support, our present health care system would implode. In their polemics, some politicians call this government support socialism or socialized medicine. I call it informed self-interest by a government concerned with the well-being of its citizens.

I practiced government medicine for over 40 years as a United States Air Force pediatrician, biomedical researcher, teacher and administrator. I witnessed massive growth in medical knowledge, the introduction of incredible new technologies and evolution of new medical skills. Hundreds of new drugs, biologics, surgical techniques, vaccines, enhanced genetic knowledge and approaches to improving mental health have revolutionized modern medicine, allowing more accurate diagnosis, real-time health monitoring, and temporary replacement of hearts, lungs and kidneys. Americans now survive cancer more often than ever before.

These new technologies and tools are only possible because the citizens of this country invested in the acquisition of knowledge, tools and services the research enterprise produced. Yet, the United States fails to equitably distribute these advances to all citizens. Health care is rationed based on ability to pay. We often spend large sums to treat patients with complex and life-threatening conditions while basic preventive care is unavailable to many families and children. Unnumbered citizens and families are bankrupted annually by catastrophic illness.

I believe the United States must redress modern health care inequities. There is much debate about how this might be done. It seems to me the fairest solution is a countrywide insurance program, or programs, to provide access to care, education, public health and protection from catastrophic illness for every person and family in the land.

This is not government takeover. It is the responsibility of government to provide life, liberty and the pursuit of happiness for all Americans, not only those who can pay. I urge all to consider voting with an eye to making our wealth of health care resources accessible to all citizens of our great country.

Val G. Hemming is the 2015 recipient of the distinguished alumni award from the University of Utah College of Medicine. He is the emeritus dean of the F. Edward Hbert School of Medicine at the Uniformed Services University of the Health Sciences in Bethesda, Md.

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Guest opinion: Why accessible health care is not government takeover - Deseret News

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Development of heat-resistant cattle in the U.S. – Post Register

Tuesday, September 15th, 2020

There are basically two types of cattle in the world today. One includes the European and British breeds that descended from the original wild cattle (Bos taurus) of those regions. The other includes the more heat-tolerant animals of the tropics (the hump-backed droopy-eared Zebu cattle, Bos indicus) that include the cattle of India, Asia and Africa). Almost all cattle breeds in the U.S. today are of British and European descent, but many ranchers in the South and Southwest prefer cattle with some Zebu breeding because they are more suited to that environment.

The American Brahman was developed from several strains of cattle imported from India between 1854 and 1926, and from imported Zebu cattle from Brazil. Since then, several American breeds and composites have been created using Brahman bloodlines, including Santa Gertrudis, Brangus, Beefmaster, etc.

Dr. Jan Bonsma of South Africa was a famous cattle geneticist and student of breed efficiency, selecting cattle for the most functional traits. He was involved in the development of two new breeds, the Bonsmara and the Beefmaster. He developed the Bonsmara by crossing native Afrikaner cattle (Zebu) with Hereford and Shorthorn to develop a hardier animal than the British breeds, with better beef quality and fertility than the Zebu. Today the Bonsmara breed he created is the most numerous breed in South Africa and these cattle have been imported to other countries around the world including the U.S.

Bonsmas concept of functional efficiency in cattle was that we need to adapt the cattle to their environment, and not the other way around. He was an advisor to Tom Lasater, who created Beefmaster cattle in the U.S. Bonsmas principles of functional efficiency and Lasaters six essentials of Beefmaster breeding created a type of cattle that can adapt to harsh environments and efficiently convert grass to a well-muscled meat carcass.

Beefmaster cattle were the first American composite breed (combination of three or more breeds). In the early 1930s, Lasater developed this blend of breeds in southern Texas. Beefmasters are a composite made up of roughly one-half Bos Taurus genetics using Hereford and Shorthorn, and one-half Bos Indicus genetics (Brahman).

The American Brahman was created earlier by using Nelore cattle from Brazil (a Zebu type that came originally from India), the Gir (a dairy breed from India) and the Guzerat--a breed developed in Brazil from the Kankrej cattle imported into Brazil from India between 1875 and 1964. The Guzerat was very instrumental in creation of the American Brahman.

The blend of British breeds with zebu type cattle (providing more heat tolerance and insect resistance) to create the Beefmaster was of great benefit to cattle raisers in Texas and other southern regions of North America. In 1937, Lasater closed his herd and no outside genetics have been introduced into the breed since that time. In

1954, the Beefmaster breed was recognized by the USDA as an American breed. Currently, Beefmaster Breeders United is the fifth-largest breed registry in the U.S. Over the last 70 years, intense selection for economically important traits has resulted in a homozygous beef breed that has the growth potential of a hybrid.

Lasater selected cattle on what he called the six essentials of disposition, fertility, weight, conformation, milk production, and hardiness. Todays Beefmaster breeders also select for calving ease, fast early growth, moderate frame, easy fleshing ability and longevity. Adhering to Lasaters six essentials make these additional goals easier and faster to accomplish.

Beefmaster cattle have strong maternal traits as well as excellent growth and carcass traits. They are well known for their ability to handle heat and drought, with more insect resistance than most British and European breeds. They tend to be moderate in size, and generally light red to dark red in color, although some have white mottling on their faces and underline. The blend of Zebu and Bos taurus creates the most hybrid vigor of any cattle cross because these types are so unrelated. The blend has created super cows.

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Development of heat-resistant cattle in the U.S. - Post Register

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Viking genetics and robots working together at Alderston Mains – The Scottish Farmer

Sunday, September 13th, 2020

Owning a Jersey herd that produces 8100 litres at 5.75%BF and 4.01%P (780kg fat plus protein), can prove problematic knowing where to turn to continue improving performance. But for Andrew Hastie and his family at Alderston Mains near Haddington in East Lothian, the answer has come through a marriage of focussed management, high quality genetics and up-to-date milking technology.

Having experienced success through a combination of the Viking Jersey and robotic milking during a gradual switch over the last three years, the Hasties have decided to follow this process to its logical end. This year, they will add their final two Lely Astronaut A5 robots, bringing their total to six (2 x A4 and 4 x A5), and theyll complete the switch to using genetics exclusively from the Viking countries (Sweden, Finland and Denmark).

With a modest acceptance that the herds production is nearer the top than the bottom, Mr Hastie remarks: Were not really far ahead of the average when you go to Denmark.

And therein lies the overriding reason for the familys choice of genetics, which sees the Vikings gradually take over from all other bloodlines.

The farms foundations were laid in the 1950s when grandfather, David Hastie, started the herd with native UK Jerseys. Since that time, Andrew and his parents, Gordon and Vivian, and brother, David, have fine-tuned both the farm and the herd, to reach the exceptional performance of today.

Over that period, the farm has switched from a mixed enterprise to one thats purely focussed on dairy, with all grass and arable crops across its 400 acres now grown exclusively for the 360-head herd. With a target of increasing the herd to 430 head, the plan is to consolidate numbers at this level.

Weve always enjoyed the Jersey and found her to have robustness and some health benefits over the Holstein, says Mr Hastie. We operate a sort of hybrid system where we want high yields but like the cows to go outside for exercise and grazing even with the robots as we feel its good for their health and keeps our feed costs down in summer.

Close attention has always been paid to the type of genetics that will best meet the farms targets, which began in the earliest days of the herd.

My grandfather was an early adopter of artificial insemination; hed use the best bulls he could get from the USA, New Zealand and Denmark and we continued breeding this mixture for a long time, he said.

Around 15 years ago we dropped the New Zealand bulls, largely because their genetics is driven by milk solids weight-based contracts, which are not quite like our own.

The USA we felt was at the other extreme, and our experience was that the taller, leaner and more angular animals didnt live so long.

We feel the Viking breeding programme has the balance just right, with cows which look long-lasting and producing high quality milk. They are particularly suited to our contract with Grahams Family Dairy, where we need to produce at least 5% fat for the Gold Top range.

In some past summers we had been slightly short of butterfat but find the VikingGenetics bulls are helpful in boosting that.

Around 18 months ago the farm also switched to sexed dairy semen which is now used alongside Aberdeen Angus beef.

Also opting to introduce genomic testing for heifers, Mr Hastie says this is giving an early indication of genetic potential across a range of traits.

When you have a cow on the ground you have a good idea of how she should breed, he says. But with a heifer, all you have is the animals pedigree, so a genomic test adds accuracy for many different traits.

There are also traits on the VikingGenetics bar chart which you dont normally have, he adds. This includes hoof health and saved feed index, which are helping us to breed cows with better feet and more efficiency.

We only started genomic testing recently but plan to test all 200 of our heifer calves born each year, he says. This supplies a linear bar chart, just like youd have for a bull, and you can see straight away what you need to improve.

It also ranks the heifers on the Nordic Total Merit [NTM] index, which is not unlike the UKs PLI [Profitable Lifetime Index].

Also using VikMate, the VikingGenetics mating program, Mr Hastie is able to set his own targets and receive a best-choice mating for each animal in the herd.

He says: If I want to focus on a particular trait, I can change that myself when running the program. This could be for hoof health, stature, milk quality or any other trait.

In fact, were already seeing big improvements in feet and legs through corrective breeding and starting to see changes in other areas.

This includes reducing udder depth and strengthening udder support we think theyll remain higher for longer and making other changes to help robotic milking.

This has involved a change of mindset and were now looking to widen rear teat placement as well as lengthen teats something we didnt do in the past.

We have also moved away from selection for production, now keeping our focus on health and functional traits. We have found that the milk is there, even without looking for it, which allows us to focus improvement on other areas.

Also aiming to improve the herds management and efficiency, the next robots to be installed will help in this endeavour.

He says: Our sixth robot will be a grazing robot, which will be used exclusively by our late lactation cows. Theyll be in strawed yards in winter and graze in summer, only receiving concentrates while at grass, when theyre having no total mixed ration.

Im confident well maintain their yields and should manage body condition score better. I think it will save 1-2 per head each day in feed costs for the last 30-40 days of lactation.

Asked how the Viking-bred cattle have impacted profitability, he believes its too early to say with any precision.

In a few years, when nearly all the herd is Danish, Ill be able to tell you but all I can say now is that we are very pleased.

FARM facts

360 milking Jerseys rising to 430 in year-round calving system

Production at 8100 litres at 5.75%BF and 4.01%P (780kg fat plus ptn)

All breeding switched to VikingGenetics for longevity and milk quality

Four A4/A5 Lely robots, increasing to six, including one grazing robot

Sexed semen produces 200 Jersey heifers/year for replacements and sale

Genomic testing introduced for all Jersey heifer calves this year

TMR fed to all milking groups except late lactation, plus concentrates to yield

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Viking genetics and robots working together at Alderston Mains - The Scottish Farmer

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Nutrition and the Wisdom of Ethnic Cuisine: A Japanese Doctor’s Perspective – Nippon.com

Sunday, September 13th, 2020

When it comes to healthy eating, one size does not fit all. Japanese cooking, with its emphasis on rice, fish, and vegetables, may not be the best diet for everyone, but it is marvelously suited to the physiology of the Japanese, writes physician and writer Okuda Masako.

The popularity of Japanese cuisine has soared in recent decades, and one reason is undoubtedly its healthful image. The average lifespan of the Japanese people climbed rapidly after World War II. By around 1980, Japan had the highest life expectancy of any country in the world, and it still ranks near the top. (The worlds oldest living person is also a Japanese woman.) Amid a slew of investigations into the secrets of Japanese longevity, attention quickly centered on the benefits of washoku, traditional Japanese cooking.

My research and experience have taught me that the optimal diet depends on a variety of hereditary and environmental factors. But there is no denying that washoku has contributed to the health and longevity of the Japanese people. Let us begin by examining how.

In terms of health and long life, the biggest physiological factor the Japanese have going for them is a low risk of atherosclerosis. Atherosclerosis occurs when fats and other substances build up along the walls of arteries, restricting or even blocking blood flow. In the brain, such a blockage is known as a cerebral infarction (stroke); in the heart, it is called a myocardial infarction (heart attack). The incidence of myocardial infarction in Japan is among the lowest in the world.

Scientists believe that both genetics and diet play a role in protecting Japanese arteries. One factor is a high level of good cholesterol, or HDL (high-density lipoproteins), in the blood. In a 2008 study, Japanese HDL levels were found to be roughly 10% higher than those of white Americans on average. Another reason is that fish is a big part of the traditional Japanese diet, and fish contains EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), two polyunsaturated fatty acids that help prevent hardening of the arteries. Since ancient times, the Japanese have been eating oily fish like mackerel, sardines, yellowtail tuna, and eel, which are abundant off the coast of Japan and are rich in EPA and DHA. In a 2015 study, the average concentration of DHA in Japanese maternal milk was determined to be up to six times that found in Western countries and about twice that found in China.

A second major contributor to Japanese health is the gut microbiota, the many and varied microorganisms living in the intestinal tract. A 2016 analysis of the intestinal microbiota of subjects from 12 countries found that the Japanese had the highest counts of beneficial bifidobacteria. (Interestingly, the gut microbiome of the Chinese subjects was closer to that of the Western subjects studied.) This can probably be attributed to the high fiber content of the traditional Japanese diet, with its emphasis on grains and vegetables. Dietary fiber provides a good nutritional environment for beneficial microbes and helps cleanse the gut of the harmful substances that unhealthy bacteria produce. Since it takes a generation or more to permanently alter the gut microbiota, todays Japanese probably owe their intestinal health to the dietary habits of their parents and grandparents.

All of this might lead one to the conclusion that eating washoku will automatically make one healthier. Unfortunately, it is not quite so simple. In general, the traditional diets that developed in various parts of the world were optimally adapted to the local environment and the needs of the native population. The physiology of the native population, in return, adapted to the diet.

There are obvious physical differences between Japanese people and Westerners. But the differences go beyond hair texture and eye color. There are also disparities in musculature, body fat, and body temperature, as well as various factors that affect digestion and metabolism of alcohol: hormone and enzyme secretion, the shape of the stomach, the composition of the gut flora, and so forth. Race is not just skin-deep.

The Japanese stomach is adapted to consumption of grain.

Figure 1 illustrates the stomach shapes typically found in Japanese people on the one hand and people of Westerners extraction on the other. The differences are the result of disparities in the traditional diet.

The Japanese have long relied on rice and other grains as their dietary staple. Grains are a good source of energy, but whole grains in particular take time to digest because of their high fiber content. The Japanese stomach is vertically elongated so as to store, mix, and break down such food before it continues on into the intestines. The intestines, in turn, are rich in the kinds of bacteria that help digest and extract nutrition from starchy foods.

By contrast, the traditional European diet, with its emphasis on meat and dairy products, is considerably higher in protein and fat. Since protein and fat are digested primarily in the intestines, the food needs to move more rapidly from the stomach to the gut. The digestive system evolved to deal with these demands. For example, a large quantity of stomach acid is produced so that the stomach can process the food quickly; comparatively thicker stomach muscles then push it smoothly into the intestines.Plenty of enzymes and other fluids are secreted to aid the digestion of fat and protein inside the intestines.

It has long been known that the ability of adults to digest milk varies by ethnicity and region. The bodys capacity to digest the lactose in milk hinges on continued production of the enzyme lactase. The map in figure 2 shows the global distribution of lactose-intolerant adults in various parts of the world, with higher concentrations indicated by darker shades. While most people in the British Isles and Scandinavia digest milk easily, close to 90% of adults in Southeast Asia and East Asia (including Japan) have trouble with it.

Darker shades indicate regions with higher rates of adult lactose intolerance.

Such differences in physiology can translate into serious health problems when people adopt different diets and lifestyles. One example involves vitamin D, which is essential to bone health, among other things. Vitamin D is produced inside the body when the skin is exposed to the suns ultraviolet rays, but it can also be obtained from dietary sources like oily fish. It has been suggested that Africans, who evolved in a part of the world where year-round UV exposure is high, may be less well equipped to absorb vitamin D from dietary sources, and this may be why African Americans tend to have relatively low vitamin-D levels. Some experts have warned that African Americans need to adjust their diets to avoid health problems resulting from vitamin D insufficiency. The optimum diet for any person depends on genetic makeup, as well as lifestyle and environment.

Genetics also influences the way our bodies accumulate fat. One characteristic of the Japanese constitution is the tendency to accumulate visceral adipose tissue, or fat inside the abdominal cavity, as opposed to the subcutaneous fat that collects under the skin. Unfortunately, visceral fat is the more worrisome kind.

Cross-sections showing the distribution of abdominal fat in representative Japanese (left) and Westerners (right) subjects.

This is a fairly recent phenomenon, mind you. In earlier times, obesity was relatively rare in Japan, and the incidence of chronic diseases associated with visceral fatincluding type 2 diabetes, along with other diseases like breast cancer and colon cancerwas correspondingly low. That began to change in the 1960s to 1980s, as the Japanese diet became increasingly westernized, leading to higher fat consumption and lower intake of fiber. And with more people doing deskwork and leading sedentary lifestyles, lack of exercise contributed to the rise of obesity and the accumulation of visceral fat. The result has been a significant increase in disease, raising concerns for the future.

Extensive studies have revealed that a traditional Japanese dietlow in meat and dairy products, high in soybeans and fish, and high in fiber from grains, vegetables, and seaweedis tied to very low accumulation of visceral fat. In other words, washoku is ideally suited to the physiological traits of the Japanese people, protecting them from their innate tendency to accumulate visceral fat. Without knowing the science, our forebears managed to develop, preserve, and pass down a dietary culture perfectly adapted to our own metabolism.

Washoku has other health benefits as well. Soybeans, green and yellow vegetables, and small fish eaten whole all help to build strong bones. Lifelong consumption of soy foods also contributes to the relativelylow incidence in Japan of diabetes, breast cancer, and colon cancer, all ailments linked closely to visceral fat levels, as compared with the West

One notable weakness of the Japanese diet as it has developed in the past two or three centuries is the overwhelming preference for polished rice. For the health-conscious, I would recommend brown rice, which has seven times the dietary fiber of white rice and contains substances that help the body burn visceral fat.

In recent years, science has made considerable progress in identifying genetic differences among ethnic groups. In 2016, a Japanese team of researchers released the first Japanese reference genome panel (JRG v1), a whole-genome assembly representing the genes of a typical healthy Japanese. Comparison with the human reference genome has revealed millions of single-nucleotide differences, many of which doubtless reflect significant differences in nutrition physiology. We need to abandon the one-size-fits-all approach to nutrition and consider what diet works best for each ethnic group.

Nowadays, the Japanese people are able to enjoy delicious cooking from every part of the world. That is a splendid thing, as long as we keep in mind that washoku is the bedrock of our much-admired health and longevity.

(Originally written in Japanese. Banner photo: Dairy and meat products figure heavily in the Western diet, while the traditional Japanese diet has much to offer in the area of human health. Pixta.)

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Anti-Aging and Prolonging Life By John Robert Cardillo – Health News Tribune

Thursday, August 13th, 2020

Youth, we all want to enjoy an extended life, and we work to find ways to perpetuate our lifespan. In the 16th century, a Spanish explorer, Ponce de Leon, explored the southern U.S. looking for the fountain of youth and ended his quest in St Augustine, Florida. His quest was to drink and bathe in the fountain, as it was believed that the waters would reverse the aging cycle and allow a man to live forever.

To many, it sounded like science fiction, as life was believed to finite experience, but not anymore. A Harvard University geneticist, Dr. David Sinclair PhD, has cracked the code of aging Working at Harvard Medical, Dr Sinclair has discovered, through multiple studies, that the aging cycle can be manipulated and reversed when certain factors are present in the equation. One of the many discoveries that he brought to academia surrounds fasting and reversing the effects of aging in humans. His experiments with yeast were the first to determine that a cause of aging for yeast as well as the role of Sir2 in epigenetic changes driven by genome instability, according to his biography at the Blavatnik Institute of Genetics at the Harvard Medical School.

In his book Lifespan, Dr. Sinclair explains that his clinics research focused primarily on sirtuins, which is a protein modifying enzyme which is responsive to changing levels of NAD during fasted calorie restriction.

Dr. Sinclair is also studying chromatin, how energy is metabolized in the mitochondria, memory and learning neurodegeneration, cancer causes.

Dr. Sinclairs Harvard Medical was credited with identifying NAD bio-synthesis in regulating lifespan, which was the first to show the involvement of sirtuins in calorie restrictions of mammals. His book states that a small molecule, resveratrol, was identified to activate on SIRT1. This improved the cells metabolic function by using combinations of enzymological, genetic, pharmacological and biophysical approaches.

They showed recently that synthetic and natural activators require SIRT-1 to mediate the in vivo effects in muscle and identified a structured activation domain.

The study concluded that the miscommunication between the mitochondrial and nuclear genomes is a cause of the age related physiological decline and the relocation of chromatin factors in response to DNA breaks may be a cause of aging

Dr. Sinclair is a renowned scientist and best-selling author and advises the world that we cant live forever, but we can live longer if we take the right steps to extend our health.

The most important discovery that Sinclair has made is the presence of Resveratrol in plants that acts as protective shield injuries and pathogens. Resveratrol is an oxidant and is found in foods like grapes, blueberries, and cocoa, and when consumed, it can counteract the aging cycle. In his seminal work, Lifespan: Why We Age- and Why We Dont Have To, Dr. Sinclair addresses a concept called health span. In a nutshell, it means that if you arent sick, dont have chronic conditions or diseases; you wont experience mortality early. In essence, if you can prolong your health span, you increase your life expectancy.

Dr. Sinclair bases his conclusion on many factors but says fasting is good for the body and is a crucial driver of human longevity. He has said on many occasions that the science behind this conclusion is now solid. For over 20 years, scientists have debunked the myth that humans need three meals a day and snacks to achieve optimal health.

Dr. Sinclair doesnt advocate starvation; he says that you dont need to be hypoglycemic and have low blood sugar because that makes us weak and dizzy. But reduced caloric intake is good for the body. Fasting activates the bodys survival instinct, and that is a good thing when it comes to anti-aging. According to Dr. Sinclair, it starts with the survival circuit, and it has been part of the human body for time eternal. The proven theory goes like this (and its in all life on the planet), when a threat occurs in the living organism, the survival circuit will be activated, and it helps us live longer and healthier when faced with danger.

The way it works is simple. When you work out and are short of breath during your workout, it is good. Suppose you wake up hungry and skip breakfast and eat a late lunch that is good also. A chemical in your body, nicotinamide adenine dinucleotide (NAD), will flood your body and the sirtuins (a protective enzyme), the critical ingredient in the survival circuit will activate.

Sinclair says that exercise is a good thing as it activates the survival cells, and movement is the reason. Exercise puts the body under pressure, and like fasting, it causes our involuntary physiology to work to protect the host.

Dr. Sinclair is an advocate of supplements to help generate the chemicals the body needs to extend life. He says that Resveratrol the NAD activator, and metformin is essential to consume for the extension of life.

Metformin is a big help for middle-aged people and older people to stave off the effects of aging. Also, it works to counteract the effects of Type-2 diabetes. It will lower rates of heart disease, cancer, frailty, and the onset of Alzheimers for people who take metformin.

Certainly, exercise will stimulate the sirtuins in our body Dr. Sinclair has said many times, but fasting is an essential component of the anti-aging cycle. Dr. Sinclair has determined in the lab that the aging cycle can be slowed and reversed. His experiments have not just stopped the aging clock; the experiments have turned back the hands of time, which is monumental. A classic example of this is an 80-year old who doesnt look their age. They are mistaken for a much younger person because they have been using fasting and exercise to force their bodies to prevent the aging cycle from creating disease and health problems that reduce our lifespans. Our molecular clocks drive our aging cycle, and when we stop that time from moving forward or slow it to a crawl, we live a lot longer than someone who hasnt engaged in exercise and fasting to create a perfect storm of anti-aging.

Dr. Sinclair said that studies in mice accentuate the point. The studies were able to extend the life of mice by 50 percent, and it only in the last ten years that the discoveries have been made.

Initially, Dr. Sinclair was branded a maverick, and a crackpot advocating that life expectancy can be extended through fasting and exercise. Dr. Sinclair says in the book that reprogramming our molecular cells will stimulate the long-lasting effects of anti-aging.

In the book, Dr. Sinclair said that scientists have been unable to decide how many times the molecular clock can be reset. Still, he sees the potential to eradicate some diseases in our lifetime. He posed if were able to turn back the molecular clock through fasting and exercise, we may be able to reduce the risk of cancer and heart disease. As humans age slower, it is forestalling the onset of illness and chronic inflammation. Sinclair does make clear, though, that humans will not live into perpetuity even if there is a reset of the clock.

In a study conducted by Dr. Sinclair in his lab at Harvard, he was able to reverse vascular aging in mice. The backstop of the book he wrote on anti-aging that tells us that fasting is the driver to helping prolong life. The molecules, NAD, and sirtuin manufactured during times of stress like exercise and fasting have caused stamina to be boosted, and endurance in the mice test subjects. The blood vessels are forced to grow, and that reverses the aging cycle for the vascular system. The experiments are the staging ground for the human condition, and the experiments will lead to addressing the root causes of diseases in humans that come from aging. Dr. Sinclair was quick to tell us that the biological differences between humans and mice are vast, and not all results in the lab can be replicated for humans.

When we age, our smallest blood cells will die, which reduces blood flow in our bodies. With reduced blood flow come vascular disease and a host of other problems attributed to old age. Reduced oxygen levels through the loss of blood flow allow toxins to build up in the body, and deterioration of the body occurs. This problem affects the endothelial cells; they line the blood vessels in our bodies and are critical to the bodys supply chain. The endothelial cells cause the growth of the blood cells that help transport oxygen and nutrients to our organs and tissues.

Aging and deterioration of muscles and blood vessels reduce life expectancy, and the endothelial cells lose a vital protein sirtuin and it is affected by the loss of NAD. NAD is our bodys protein regulator, and it is the repair kit for our DNA.

When mice were subjected to an exercise-based program, the signs of aging were slowed and eventually reversed. When the exercise wasnt present in the test subjects, proteins were reduced, and the process for regeneration of blood vessels wasnt activated.

When NAD and sirtuins were created with exercise and fasting, the body demonstrated an innate ability to fight off the aging process.

The mitochondrial networks that exist inside our cells are where the reactions take place. Through dietary restrictions and exercise, the mitochondria can increase your lifespan and improve your current health. The mitochondria are the energy factory for our body and can shapeshift according to the bodys energy demands. As we age, the dynamic of the function of the reaction slows, and it impacts our metabolism. Through exercise and fasting, the chemical reactions created work in unison to keep threats at bay and supply the organs through the bloodstream with the chemicals the body needs to fight off threats.

Through a series of studies, fasting or dietary restrictions manipulated through an energy identifying protein kinase helped the mitochondrial networks maintain youthfulness.

The process was termed healthy aging, and understanding the process is critical to advancing the application to humans to slow aging. Dr. Sinclair and other scientists have understood that fasting slows the aging process, but they dont have a handle as to why it occurs in the body chemistry.

To begin to understand the process and how it reflects in obesity will be the next step to a longer life. Obesity can be linked to defective mitochondrial flexibility and the increase in age-related diseases and chronic conditions from obesity.

The scientific community only just understands the biological manifestations of the human body. Still, Sinclair and other researchers have learned that exercise and fasting are essential components to slowing the aging process internally.

John Cardillo is a Canadian body building champion, renownerd fitness entrepreneur and the pioneer of the HIT3 exercise program. John Cardillo is Canadas premier health and fitness expert!

Erik Horn has been a senior editor at Health News Tribune for three years. Fluent in French and proficient in Spanish and Arabic, he focuses on diseases and conditions Hes a born-and-raised Torontonian and spends most of his weekends in search of strong coffee and stronger Wi-Fi.

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Environmental legislation to be biggest limiting factor for NI dairying in 2030 – Agriland.co.uk

Thursday, August 13th, 2020

One of Northern Irelands leading dairy researchers has warned he expects environmental legislation to be one of the biggest limiting factors to the industry locally by 2030.

Speaking as part of the Agri Food and Biosciences Institute (AFBI) webinar The Future of Dairy Production to 2030, Dr. Conrad Ferris said environmental factors, such as ammonia emissions, had already begun to impact the industrys growth.

Dr. Ferris said: As we look to the future for our dairy sector there are certainly lots of challenges, but as in most areas of life, challenges often bring opportunities.

Structural changes over the last 20 years have seen the total number of herds fall by around 25 a year. Meanwhile, the average herd size has increased by around two cows a year.

However, Dr. Ferris said he believed total cow numbers will remain relatively stable over the next decade.

Production in terms of litres has continued to grow, currently increasing by around 55L/cow/year. And I dont see any reason to believe that is going to slow down, he said.

Certainly, with genetic indexes, we can continue to improve production and improve fertility and health.

However, I do believe the biggest challenge to the overall structure of the dairy sector going forward is environmental legislation and I believe that is what will probably have the biggest impact on the structure of the local dairy sector.

Legislation is already impacting herd expansion on some farms, he added, referring to delays over agricultural planning associated with tightened restrictions over ammonia emissions.

Dr. Ferris said it was likely environmental legislation would continue to tighten for the industry. However, explained that anything the sector can do to become more efficient would have benefits for both its profitability and its environmental impact.

In terms of genetics and nutrition, I think there is a real win-win situation in that we know that anything we do to improve the overall efficiency of the whole milk production system right from calf-rearing, getting heifers calving down at 24 months, increasing longevity, the whole picture reduces greenhouse gases and ultimately improves profitability, Dr. Ferris said.

Over the last two decades, we have seen a real escalation in environmental challenges for dairy farmers. Back around 2000, water quality issues became a big issue in Northern Ireland driven by the Nitrates Directive and water quality in regards to phosphorous.10 years later, it was the climate change issue.

The key thing here is that it is cumulative just because now we are focused on ammonia doesnt mean that issues like water quality and climate change have gone away.

In reality, we are now trying to deal with all three of these, while 20 years ago we were only focused on water quality.

Dr. Ferris explained thatmany gains made in terms of water quality had been lost in recent years. Soluble reactive phosphorous levels in rivers had fallen from 2005 until 2012 but have now risen back to the 2007 figure almost wiping out 15 years worth of progress.

There are all sorts of reasons for that. But in terms of [agriculture], I do believe that reducing phosphorous levels in our concentrates, which is something our feed industry has already adopted. [This is] something that, going forward, we will have to push further and we will likely have to move even lower in terms of new levels.

As a result, research is expected to begin soon at AFBI examining the impact of lower protein diets for dairy cows. It will test what effect reducingprotein in cows diets has on farm ammonia emissions.

Meanwhile, promising research carried out by the institute also shows the potential to replace imported feedstocks with protein sources grown in Northern Ireland.

As part of the study, researchers were able to replace imported soya with locally-grown field beans completely without major impacts on milk composition. Reducing the food miles of animal feed could help further reduce the industrys emissions.

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Healthy ageing.. The eight R’s – Daijiworld.com

Thursday, August 13th, 2020

Aug 13, 2020

Each one of us aspires to live a long and healthy life. The environment we live in influences our behaviour, and exposure to risk. Thus a need arises for quality health and support. Every one of us can experience healthy ageing. Healthy Aging is developing the environments and opportunities that enable people to be and do what they value throughout their lives.

WHO defines Healthy ageing as the process of developing and maintaining the functional ability that enables wellbeing in older age. Functional ability is made up of the inner capacity of the individual, relevant environmental conditions, and the interaction between them. The inner capacity is influenced by factors like mental and physical behaviours, genes, age-related changes, and genetics. The Environment includes housing, community, transportation, attitudes, values, social facilities, assistive technologies, and the support system.

Elderly is an incredibly valuable resource for society and to continue being an active person in the society, elderly too without age discrimination should participate/engage and or get opportunities in activities boosting their physical, social and mental wellbeing. The decade from 2020 to 2030 is described by the United Nations as a 'Decade of healthy aging'. Older people are the main focus of this plan and also an aim to bring together civil society, governments, interdisciplinary professionals, international agencies, media, and private sectors to improve the lives of older people, their families, and communities. Through this article, I would like to mention the 8Rs as tips for healthy aging.

1. Regular exercise and physical activity: Exercising regularly and involving oneself in physical activities like walking with the pet, gardening, using stairs, and brisk walking increases stamina and improves health. Exercises help to prevent falls, reduces the risk of bone stiffening, and free movement of muscles. It can be an effective treatment for diseases like arthritis, heart ailments, diabetes, etc.

2. Routine checkups: Ageing itself is a challenge to be healthy, leading to increased doctors visits and need to care. With proper health check-up packages, physicians can detect the early signs of disease and help maintain the baseline and promote healthier aging. Other than the routine tests we undergo, depending on the gender there are additional tests that one needs to check. Its also necessary that like the way we check our physical and functional health, due importance should also be given to our cognitive and emotional health.

3. Relax: Engaging in the activities of ones interests can be relaxing. Sticking to the sleep schedule helps the elderly with insomnia. Some simple tips to be followed include avoid caffeine in the evening, keep the bedroom dark, turn off the cell phone, avoid naps more than 20 minutes during daytime, etc. Deep breathing and meditation can help ease stress, pain, and increase flexibility. Keeping a gratitude journal strengthens emotional resilience.

4. Rich nutritious diet: Many health issues are connected to overweight or obesity but being thinner is not healthier either. Dietary patterns influence the BMI, thus diet must include fibre-rich foods, low-fat dairy products, fruits, vegetables, and lean meat products. Supplements strictly prescribed by doctors like calcium, vitamin B6, B12, and D can be included. Intake of enough liquids is necessary not to get dehydrated.

5. Recreational activities: Well-planned recreations such as listening to music of interest, involving in art and craft, visiting old friends, playing board games, volunteering work, and engaging in old hobbies helps elderly utilize their leisure time, and improve their physical and psychological wellbeing.

6. Restrain from alcohol, smoking, and other addictions: Recent studies have shown that midlife and late-life smokers had a greater risk of developing dementia. Tobacco harmed daily functioning. (Michel et al, 2016). The positive effect of light to moderate alcohol consumption on longevity was completely rejected by a 6 year follow up Pianoro study. Systematic review and meta-analysis of longitudinal studies on alcohol consumption and healthy ageing revealed equivocal results. (Daskalopoulou, et al, 2018). However, it needs more research in this area.

7. Research on healthy ageing: Practitioners, professionals, and researchers must consider research addressing topics on the current needs of elderly, future challenges, and determinants of healthy ageing and interventions to improve healthy ageing trajectories. Studies can also emphasize on research priorities and gaps to improve health equity. Thus contributing to and learn from such a knowledge base.

8. Reverse approach: We will not hold their hands; they will hold our hands. One should not underestimate the elderly power only due to their age. The knowledge, skills, and experience they have should not be devalued. Important here is they should not be placed in the receiving end. They are an asset and guide for preserving the cultural and folk traditions, old values, and rituals.

I would also like to inform the readers that the Manipal Academy of Higher Education (MAHE) in May 2020 has launched the Centre for Studies on Healthy Ageing (CSHA) aiming to promote health and participation in old age. The centre also encourages young groups to age healthy and be independent.

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The Secret to a Long, Healthy Life Is in the Genes of the Oldest Humans Alive – Singularity Hub

Monday, August 10th, 2020

The first time I heard nematode worms can teach us something about human longevity, I balked at the idea. How the hell can a worm with an average lifespan of only 15 days have much in common with a human who lives decades?

The answer is in their genesespecially those that encode for basic life functions, such as metabolism. Thanks to the lowly C. elegans worm, weve uncovered genes and molecular pathways, such as insulin-like growth factor 1 (IGF-1) signaling that extends healthy longevity in yeast, flies, and mice (and maybe us). Too nerdy? Those pathways also inspired massive scientific and popular interest in metformin, hormones, intermittent fasting, and even the ketogenic diet. To restate: worms have inspired the search for our own fountain of youth.

Still, thats just one success story. How relevant, exactly, are those genes for humans? Were rather a freak of nature. Our aging process extends for years, during which we experience a slew of age-related disorders. Diabetes. Heart disease. Dementia. Surprisingly, many of these dont ever occur in worms and other animals. Something is obviously amiss.

In this months Nature Metabolism, a global team of scientists argued that its high time we turn from worm to human. The key to human longevity, they say, lies in the genes of centenarians. These individuals not only live over 100 years, they also rarely suffer from common age-related diseases. That is, theyre healthy up to their last minute. If evolution was a scientist, then centenarians, and the rest of us, are two experimental groups in action.

Nature has already given us a genetic blueprint for healthy longevity. We just need to decode it.

Long-lived individuals, through their very existence, have established the physiological feasibility of living beyond the ninth decade in relatively good health and ending life without a period of protracted illness, the authors wrote. From this rare but valuable population, we can gain insight into the physiology of healthy aging and the development of new therapies to extend the human healthspan.

While it may seem obvious now, whether genes played a role in longevity was disputed for over a century. After all, rather than genes, wouldnt access to health care, socioeconomic status, diet, smoking, drinking, exercise, or many other environmental and lifestyle factors play a much larger role? Similar to height or intelligence (however the latter is assessed), the genetics of longevity is an enormously complicated and sensitive issue for unbiased studying.

Yet after only a few genetic studies of longevity, a trend quickly emerged.

The natural lifespan in humans, even under optimal conditions in modern societies, varies considerably, the authors said. One study, for example, found that centenarians lived much longer than people born around the same time in the same environment. The offspring of centenarians also have lower chances of age-related diseases and exhibit a more youthful profile of metabolism and age-related inflammation than others of the same age and gender.

Together, about 25 to 35 percent of the variability in how long people live is determined by their genesregardless of environment. In other words, rather than looking at nematode worm genes, we have a discrete population of humans whove already won the genetic lottery when it comes to aging. We just need to parse what winning means in terms of biology. Genes in hand, we could perhaps tap those biological phonelines and cut the wires leading to aging.

Identification of the genetic factors that underlie extreme human lifespan should provide insights into the mechanisms of human longevity and disease resistance, the authors said.

Once scientists discovered that genes play a large role in aging, the next question was which ones are they?

They turned to genome-wide association studies, or GWAS. This big data approach scans existing genomic databases for variations in DNA coding that could lead to differences in some outcomefor example, long versus short life. The differences dont even have to be in so-called coding genes (that is, genes that make proteins). They can be anywhere in the genome.

Its a powerful approach, but not that specific. Think of GWAS as rudimentary debugging software for biological code: it only looks for differences between different DNA letter variants, but doesnt care which specific DNA letter swap most likely impacts the final biological program (aging, in this case).

Thats a huge problem. For one, GWAS often finds dozens of single DNA letter changes, none powerful enough to change the trajectory of aging by itself. The technique highlights a village of DNA variants, that together may have an effect on aging by controlling the cells course over a lifetime, without indicating which are most important. Its also hard to say that a DNA letter change causally leads to (or protects against) aging. Finally, GWAS studies are generally performed on populations of European ancestry, which leaves out a huge chunk of humansfor example, the Japanese, who tend to produce an outsized percentage of centenarians.

So what needs to change?

Rather than focusing on the general population, the key is to home in on centenarians of different cultures, socioeconomic status, and upbringing. If GWAS are like fishing for a rare species in several large oceans, then the authors point is to focus on pondsdistributed across the worldwhich are small, but packed with those rare species.

Extremely long-lived individuals, such as centenarians, compose only a tiny proportion (~0.01 percent to 0.02 percent) of the United States population, but their genes contain a biological blueprint for healthy aging and longevity, the authors said. Theyre spared from usual age-related diseases, and this extreme and extremely rare phenotype is ideal for the study of genetic variants that regulate healthspan and lifespan.

Its an idea that would usually make geneticists flinch. Its generally thought that the larger the study population, the better the result. Here, the recommendation is to narrow our focus.

And thats the point, the authors argue.

Whatever comes out of these studies will likely have a much larger impact on aging than a GWAS fishing experiment. Smaller (genomic) pond; larger (pro-youth) fish. Whats more, a pro-youth gene identified in one European-based long-living population can be verified in another group of centenarianssay, Japaneseensuring that the gene candidates reflect something fundamental about human aging, regardless of race, culture, upbringing, and wealth.

A genomic screen of centenarians can easily be done these days on the cheap. But thats only the first step.

The next step is to validate promising anti-aging genetic differences, similar to how scientists validated such differences in nematode worms during classic longevity studies. For example, a promising pro-youth gene variant can be genetically edited into mice using CRISPR or some other tool. Scientists can then examine how the mice grow up and grow old, compared to their non-edited peers. Does the gene make these mice more resilient to dementia? What about muscle wasting? Or heart troubles? Or hair greying and obesity?

From these observations, scientists can then use an enormous selection of molecular tools to further dissect the molecular pathways underlying these pro-youth genetic changes.

The final step? Guided by centenarian genes and validated by animal models of aging, we can design powerful drugs that sever the connection between the genes and proteins that drive aging and its associated diseases. Metformin is an experimental pill that came out of aging studies in nematode wormsimagine what studies in human centenarians will yield.

Despite enormous improvements in human health over the past century, we remain far from a situation in which living to 100 years of age in fairly good health is the norm, the authors said.

But as centenarians obviously prove, this is possible. By digging into their genes, scientists may find a path towards healthy longevitynot just for the genetically fortunate, but for all of us.

Image credit:Cristian Newman / Unsplash

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What We Can Learn About Longevity From SuperAgers and Centenarians – Next Avenue

Monday, August 10th, 2020

Editors note: This article is part of an editorial partnership between Next Avenue and The American Federation for Aging Research (AFAR), a national nonprofit whose mission is to support and advance healthy aging through biomedical research.

Dr. Nir Barzilais research as director of the Einstein-Institute for Aging Research and AFAR scientific director explores the genetics and biology of aging through the lens of exceptional longevity. He is a pioneer in the study of centenarians and, as one step in the process of understanding how we age, looking at the cellular level to see how centenarians genes can point to opportunities to delay aging or protect against age-related disease.

He is also co-founder of biotech firms CohBar and Lifebiosciences, who are developing therapies to extend health by targeting aging, and is principal investigator for the TAME (Targeting Aging with Metformin) Trial, which aims to provide proof of concept that aging can be targeted and treated.

Barzilai recently published his first book, Age Later: Health Span, Life Span, and the Science of Longevity. We spoke with him to learn about his research on those who live past 100.

American Federation of Aging Research: What are SuperAgers and what does the study of these individuals tell you about longevity?

Dr. Nir Barzilai: SuperAgers are people who have aged more slowly than others. In other words, SuperAgers chronological age does not reflect their biological age. They do not accumulate age-related disease and require treatment, which allows them to work longer, enjoy post-retirement interests, to live life to the fullest.

Centenarians, as well as many older adults, do survive COVID-19.

In my studies, not only did SuperAgers live twenty to thirty more healthy years, they also had a contraction of morbidity. This means they spent less time being sick and therefore there is a longevity dividend among SuperAgers as medical costs are saved.

How can your study of genes in centenarians or their offspring translate to drug discovery efforts?

The interesting thing about discovering specific changes in the genes of centenarians and their offspring is that those genes can point to a mechanism that can be targeted for intervention. We can look to these mechanisms for developing drugs that inhibit or stimulate these genes.

Through the Longevity Genes Project at Einstein, we have found two such changes in genes that control the good aspect of lipid metabolism. These discoveries led to the development of a drug and successful Phase 2 studies by the pharmaceutical companies Merck and Ionis. [Barzilai is on Mercks advisory board.] The indications for the development of these drugs was cardiovascular disease, but they may impact other diseases as well.

The disproportionate impact of COVID-19 on older adults has been well documented, but what can be learned from older adults, even centenarians, who survive the virus?

Centenarians, as well as many older adults, do survive COVID-19. While we must be sensitive to the range of socioeconomic factors impacting how and who COVID-19 is affecting in America, its important to look at the hallmarks of aging.

On a cellular level, these hallmarks are processes that are considered to be the core underlying machinery controlling how our bodies age. COVID-19 vulnerability is linked to two of the hallmarks of aging: immune decline and inflammation. Some older adults experience these hallmarks at lower levels.

Further, research has shown that immunity among offspring of centenarians is better than that of others their age. Because all hallmarks of aging are involved, not just the immune system, these individuals are able to survive through a severe disease like COVID-19.

In Age Later, you pose the question: Is it possible to grow older without getting sicker? How have your thoughts on this question changed since the coronavirus pandemic?

COVID-19 has put a spotlight on how the biology of aging makes some of us more or less vulnerable to viruses and sickness. The field of aging research has been looking at this for decades, and now we can apply our expertise to COVID-19 and expand the conversation on targeting age-related diseases and extending health span our years of health as we age.

I always say that a future of healthy aging is not just a hope, but a promise: not only have we gone from the promise of targeting aging, but there are drugs that can do this in use by humans today. Those drugs can change biological age and improve immunity not only against COVID-19, but against the next pathogen.

For example, metformin is a drug that can target aging in humans. There are several papers that show COVID-19 patients on metformin were hospitalized less and had lower mortality than patients with similar problems who were not treated with metformin. We need to move rapidly to consider available drugs like this that can help defend older adults against threats like COVID-19 now and those in the future.

This also why we need the TAME Trial. At fourteen leading research institutions across the country, we hope to engage over three thousand individuals between the ages of sixty-five and seventy-nine to test whether those taking metformin experience delayed development or progression of age-related chronic diseases such as heart disease, cancer, and dementia.

The TAME Trial seeks an indication for aging from the FDA [Food and Drug Administration], and this would open the door to so many promising therapies to extend health.

Im passionate about the therapeutics that are within our reach and their promise to extend health as we grow older. My book may be called Age Later, but it really could be called Healthier Longer. The promise that we all can live healthier for longer as we grow older and decrease the pain of disease and illness is really what motivates me and my inspiring colleagues in the field.

Dr. Barzilai will be talking about his book at an online event on Thursday, Aug. 27, 2020 at 2 pm ET (RSVP required). The talk is part of AFARs Live Better Longer series with Prevention magazine, and is part of an editorial and promotional partnership with Next Avenue.

Next Avenue brings you stories that are inspiring and change lives. We know that because we hear it from our readers every single day. One reader says,

"Every time I read a post, I feel like I'm able to take a single, clear lesson away from it, which is why I think it's so great."

Your generous donation will help us continue to bring you the information you care about. What story will you help make possible?

Next Avenue - 2020. All rights reserved.

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How to live longer – the anti-ageing spice to protect against an early death and cancer – Express

Monday, August 10th, 2020

Maintaining a healthy lifestyle, including a well-rounded diet is crucial to prolonging your lifespan.

You could also boost your lifespan by doing regular exercise. Its the miracle cure weve all been waiting for, according to the NHS.

Making some small diet or lifestyle changes could help to increase your life expectancy and avoid an early death.

One of the best ways to make sure that you live a long and healthy life is to eat more turmeric, it's been revealed.

READ MORE: How to live longer - the amount of exercise you need to do each day

"Many people think that life expectancy is largely determined by genetics," the dietitian wrote on medical website Healthline.

"However, genes play a much smaller role than originally believed. It turns out that environmental factors like diet and lifestyle are key.

"When it comes to anti-aging strategies, turmeric is a great option. Thats because this spice contains a potent bioactive compound called curcumin.

"Due to its antioxidant and anti-inflammatory properties, curcumin is thought to help maintain brain, heart, and lung function, as well as protect against cancers and age-related diseases."

Meanwhile, you could also lower your risk of an early death by eating more nuts, it's been claimed.

They're particularly rich in proteins, fibre, antioxidants, and magnesium.

Scientists have previously revealed that they could protect against heart disease and high blood pressure.

Everyone should aim to eat a handful of nuts everyday; the equivalent to around 30g.

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Global Precision Medicine Software Industry Market 2020 Size, Share, Trends, Growth and Outlook with Company Analysis and Forecast to 2025 – CueReport

Monday, August 10th, 2020

The research report on Precision Medicine Software Industry market comprises of key development trends that define the industry in terms of profit potential and expansion scope. It also highlights the challenges & constraints that may negatively influence the market outlook alongside the various growth drivers and opportunities affecting the future remuneration of this business vertical. In addition, the study encompasses data regarding the impact of COVID-19 in an effort to gain insights about the projected performance over the study duration.

Major aspects from COVID-19 impact analysis:

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A summary of the geographical landscape:

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Other key aspects from the Precision Medicine Software Industry market report:

Major Points Covered in TOC:

Overview:Along with a broad overview of the global Precision Medicine Software Industry market, this section gives an overview of the report to give an idea about the nature and contents of the research study.

Analysis of Strategies of Leading Players:Market players can use this analysis to gain a competitive advantage over their competitors in the Precision Medicine Software Industry market.

Study on Key Market Trends:This section of the report offers a deeper analysis of the latest and future trends of the market.

Market Forecasts:Buyers of the report will have access to accurate and validated estimates of the total market size in terms of value and volume. The report also provides consumption, production, sales, and other forecasts for the Precision Medicine Software Industry market.

Regional Growth Analysis:All major regions and countries have been covered in the report. The regional analysis will help market players to tap into unexplored regional markets, prepare specific strategies for target regions, and compare the growth of all regional markets.

Segmental Analysis:The report provides accurate and reliable forecasts of the market share of important segments of the Precision Medicine Software Industry market. Market participants can use this analysis to make strategic investments in key growth pockets of the market.

Key questions answered in the report:

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Precision Medicine Software Market Size By Product Analysis, Application, End-Users, Regional Outlook, Competitive Strategies And Forecast Up To 2026…

Sunday, July 12th, 2020

New Jersey, United States,- Latest update on Precision Medicine Software Market Analysis report published with extensive market research, Precision Medicine Software Market growth analysis, and forecast by 2026. this report is highly predictive as it holds the overall market analysis of topmost companies into the Precision Medicine Software industry. With the classified Precision Medicine Software market research based on various growing regions, this report provides leading players portfolio along with sales, growth, market share, and so on.

The research report of the Precision Medicine Software market is predicted to accrue a significant remuneration portfolio by the end of the predicted time period. It includes parameters with respect to the Precision Medicine Software market dynamics incorporating varied driving forces affecting the commercialization graph of this business vertical and risks prevailing in the sphere. In addition, it also speaks about the Precision Medicine Software Market growth opportunities in the industry.

Precision Medicine Software Market Report covers the manufacturers data, including shipment, price, revenue, gross profit, interview record, business distribution etc., these data help the consumer know about the competitors better. This report also covers all the regions and countries of the world, which shows a regional development status, including Precision Medicine Software market size, volume and value, as well as price data.

Precision Medicine Software Market competition by top Manufacturers:

Precision Medicine Software Market Classification by Types:

Precision Medicine Software Market Size by End-user Application:

Listing a few pointers from the report:

The objective of the Precision Medicine Software Market Report:

Cataloging the competitive terrain of the Precision Medicine Software market:

Unveiling the geographical penetration of the Precision Medicine Software market:

The report of the Precision Medicine Software market is an in-depth analysis of the business vertical projected to record a commendable annual growth rate over the estimated time period. It also comprises of a precise evaluation of the dynamics related to this marketplace. The purpose of the Precision Medicine Software Market report is to provide important information related to the industry deliverables such as market size, valuation forecast, sales volume, etc.

Major Highlights from Table of contents are listed below for quick lookup into Precision Medicine Software Market report

About Us:

Market Research Intellect provides syndicated and customized research reports to clients from various industries and organizations with the aim of delivering functional expertise. We provide reports for all industries including Energy, Technology, Manufacturing and Construction, Chemicals and Materials, Food and Beverage, and more. These reports deliver an in-depth study of the market with industry analysis, the market value for regions and countries, and trends that are pertinent to the industry.

Contact Us:

Mr. Steven Fernandes

Market Research Intellect

New Jersey ( USA )

Tel: +1-650-781-4080

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Precision Medicine Software Market (impact of COVID-19) Growth, Overview with Detailed Analysis 2020-2026| Syapse, Allscripts, Qiagen, Roper…

Sunday, July 12th, 2020

GlobalPrecision Medicine SoftwareMarket (COVID-19 Impact) Size, Status and Forecast 2020-2026

This report studies thePrecision Medicine Software marketwith many aspects of the industry like the market size, market status, market trends and forecast, the report also provides brief information of the competitors and the specific growth opportunities with key market drivers. Find the completePrecision Medicine Software marketanalysis segmented by companies, region, type and applications in the report.

New vendors in the market are facing tough competition from established international vendors as they struggle with technological innovations, reliability and quality issues. The report will answer questions about the current market developments and the scope of competition, opportunity cost and more.

The major players covered in Precision Medicine Software Market:Syapse, Allscripts, Qiagen, Roper Technologies, Fabric Genomics, Foundation Medicine, Sophia Genetics, PierianDx, Human Longevity, Translational Software, Gene42, Inc, Lifeomic Health

The final report will add the analysis of the Impact of Covid-19 in this report Precision Medicine Software industry.

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Global Precision Medicine Software Market: Competitive Landscape

This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2020 to 2026.

Precision Medicine SoftwareMarket in its database, which provides an expert and in-depth analysis of key business trends and future market development prospects, key drivers and restraints, profiles of major market players, segmentation and forecasting. An Precision Medicine Software Market provides an extensive view of size; trends and shape have been developed in this report to identify factors that will exhibit a significant impact in boosting the sales of Precision Medicine Software Market in the near future.

This report focuses on the globalPrecision Medicine Softwarestatus, future forecast, growth opportunity, key market and key players. The study objectives are to present the Precision Medicine Software development inUnited States, Europe, China, Japan, Southeast Asia, India, and Central & South America.

Market segment by Type, the product can be split into

Market segment by Application, split into

ThePrecision Medicine Softwaremarket is a comprehensive report which offers a meticulous overview of the market share, size, trends, demand, product analysis, application analysis, regional outlook, competitive strategies, forecasts, and strategies impacting the Precision Medicine Software Industry. The report includes a detailed analysis of the market competitive landscape, with the help of detailed business profiles, SWOT analysis, project feasibility analysis, and several other details about the key companies operating in the market.

The study objectives of this report are:

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ThePrecision Medicine Softwaremarket research report completely covers the vital statistics of the capacity, production, value, cost/profit, supply/demand import/export, further divided by company and country, and by application/type for best possible updated data representation in the figures, tables, pie chart, and graphs. These data representations provide predictive data regarding the future estimations for convincing market growth. The detailed and comprehensive knowledge about our publishers makes us out of the box in case of market analysis.

Key questions answered in this report

Table of Contents

Chapter 1:GlobalPrecision Medicine SoftwareMarket Overview

Chapter 2:Precision Medicine Software Market Data Analysis

Chapter 3:Precision Medicine Software Technical Data Analysis

Chapter 4:Precision Medicine Software Government Policy and News

Chapter 5:Global Precision Medicine Software Market Manufacturing Process and Cost Structure

Chapter 6:Precision Medicine Software Productions Supply Sales Demand Market Status and Forecast

Chapter 7:Precision Medicine Software Key Manufacturers

Chapter 8:Up and Down Stream Industry Analysis

Chapter 9:Marketing Strategy -Precision Medicine Software Analysis

Chapter 10:Precision Medicine Software Development Trend Analysis

Chapter 11:Global Precision Medicine Software Market New Project Investment Feasibility Analysis

About Us:

Reports and Marketsis not just another company in this domain but is a part of a veteran group calledAlgoro Research Consultants Pvt. Ltd. It offers premium progressive statistical surveying, market research reports, analysis & forecast data for a wide range of sectors both for the government and private agencies all across the world. The database of the company is updated on a daily basis. Our database contains a variety of industry verticals that include: Food Beverage, Automotive, Chemicals and Energy, IT & Telecom, Consumer, Healthcare, and many more. Each and every report goes through the appropriate research methodology, Checked from the professionals and analysts.

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Global Precision Medicine Software Market Analysis and Forecast 2027- including drivers, constraints, intimidation, challenges, opportunities, and…

Saturday, July 11th, 2020

Global Precision Medicine Software Market presents insights into the present and upcoming industry trends, enabling the readers to identify the products and services, hence driving the enlargement and effectiveness. The research report provides a comprehensive breakdown of all the major factors impacting the market on a global and regional scale, including drivers, constraints, intimidation, challenges, opportunities, and industry-specific trends. Further, the report cites global certainties and endorsements along with downstream and upstream analysis of leading players.

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Major Players:

Abbott Laboratories(US)Syapse, Inc. (US)Roper Technologies(US)Sunquest Information Systems Inc. (US)Pfizer, Inc., Merck & Co., Inc.(US)N-of-One, Inc. (US)NantHealth, Inc. (US)LifeOmic Health, LLC (US)Fabric Genomics (US)Allscripts(US)GlaxoSmithKline plc(UK)Gene42, Inc. (Canada)Foundation Medicine, Inc. (US)Koninklijke Philips N.V. (Netherlands)PierianDx, Inc. (US)Translational Software, Inc. (US)Flatiron Health, Inc. (US)IBM Watson Group (US)Sanofi S.A.(France)Tempus Labs, Inc. (US)AstraZeneca plc(US)2bPrecise LLC (Israel)Qiagen(Germany)SOPHiA GENETICS SA (Switzerland)Human Longevity, Inc. (US)

Global Precision Medicine Software Market research reports enlargement rates and the market value based on market dynamics, growth factors. Complete knowledge is based on the newest innovation in business, opportunities, and trends. In addition to SWOT examination by key suppliers, the report contains an all-inclusive market analysis and major players landscape.

The regional segmentation covers:

Segmentation by Type:

Cloud-basedOn-premise

Segmentation by Application:

Healthcare providersResearch centers & Government institutesPharmaceutical & Biotechnology companiesOther end users

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Report Objectives

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Table of Content:

The Global Precision Medicine Software Market

Chapter 1: Precision Medicine Software Market Overview, Drivers, Restraints and Opportunities

Chapter 2: Precision Medicine Software Market Competition by Manufacturers

Chapter 3: Precision Medicine Software Production by Regions

Chapter 4: Production, By Types, Market share by Types

Chapter 5: Consumption, By Applications

Chapter 6: Comprehensive profiling and analysis of Manufacturers

Chapter 7: Manufacturing cost analysis

Chapter 8: Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 9: Marketing Strategy Analysis, Distributors/Traders

Chapter 10: Precision Medicine Software Market Effect Factors Analysis

Chapter 11: Precision Medicine Software Market Forecast

Chapter 12: Conclusion of Precision Medicine Software Market

The Report has Tables and Figures Browse The Report Description and TOC @ https://www.globalmarketers.biz/report/others/2015-2027-global-precision-medicine-software-industry-market-research-report,-segment-by-player,-type,-application,-marketing-channel,-and-region/146709#table_of_contents

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Research On Global Genomic Biomarker Market (impact of COVID-19) with Top Players: Bio-Rad,Beckman Coulter,Myriad Genetics and Others – Owned

Saturday, July 11th, 2020

Global Genomic Biomarker Market: Trends Estimates High Demand by 2027

The Genomic Biomarker Market 2020 report includes the market strategy, market orientation, expert opinion and knowledgeable information. The Genomic Biomarker Industry Report is an in-depth study analyzing the current state of the Genomic Biomarker Market. It provides a brief overview of the market focusing on definitions, classifications, product specifications, manufacturing processes, cost structures, market segmentation, end-use applications and industry chain analysis. The study on Genomic Biomarker Market provides analysis of market covering the industry trends, recent developments in the market and competitive landscape.

It takes into account the CAGR, value, volume, revenue, production, consumption, sales, manufacturing cost, prices, and other key factors related to the global Genomic Biomarker market. All findings and data on the global Genomic Biomarker market provided in the report are calculated, gathered, and verified using advanced and reliable primary and secondary research sources. The regional analysis offered in the report will help you to identify key opportunities of the global Genomic Biomarker market available in different regions and countries.

The final report will add the analysis of the Impact of Covid-19 in this report Genomic Biomarker industry.

Some of The Companies Competing in The Genomic Biomarker Market are: Bio-Rad,Beckman Coulter,Myriad Genetics,Thermo Fisher Scientific,Roche,QIAGEN,Epigenomics,Almac,Pfizer,Human Longevity,ValiRx,Personalis,Eagle Genomics,Empire Genomics,Agilent,Illumina.

Get a Sample Copy of the [emailprotected] https://www.reportsandmarkets.com/sample-request/global-genomic-biomarker-market-size-status-and-forecast-2019-2025?utm_source=jewishlifenews&utm_medium=46

The report scrutinizes different business approaches and frameworks that pave the way for success in businesses. The report used Porters five techniques for analyzing the Genomic Biomarker Market; it also offers the examination of the global market. To make the report more potent and easy to understand, it consists of info graphics and diagrams. Furthermore, it has different policies and improvement plans which are presented in summary. It analyzes the technical barriers, other issues, and cost-effectiveness affecting the market.

Global Genomic Biomarker Market Research Report 2020 carries in-depth case studies on the various countries which are involved in the Genomic Biomarker market. The report is segmented according to usage wherever applicable and the report offers all this information for all major countries and associations. It offers an analysis of the technical barriers, other issues, and cost-effectiveness affecting the market. Important contents analyzed and discussed in the report include market size, operation situation, and current & future development trends of the market, market segments, business development, and consumption tendencies. Moreover, the report includes the list of major companies/competitors and their competition data that helps the user to determine their current position in the market and take corrective measures to maintain or increase their share holds.

What questions does the Genomic Biomarker market report answer pertaining to the regional reach of the industry?

The report claims to split the regional scope of the Genomic Biomarker market into North America, Europe, Asia-Pacific, South America & Middle East and Africa. Which among these regions has been touted to amass the largest market share over the anticipated duration

How do the sales figures look at present how does the sales scenario look for the future?

Considering the present scenario, how much revenue will each region attain by the end of the forecast period?

How much is the market share that each of these regions has accumulated presently

How much is the growth rate that each topography will depict over the predicted timeline

A short overview of the Genomic Biomarker market scope:

Global market remuneration

Overall projected growth rate

Industry trends

Competitive scope

Product range

Application landscape

Supplier analysis

Marketing channel trends Now and later

Sales channel evaluation

Market Competition Trend

Market Concentration Rate

Reasons to Read this Report

This report provides pin-point analysis for changing competitive dynamics

It provides a forward looking perspective on different factors driving or restraining market growth

It provides a six-year forecast assessed on the basis of how the market is predicted to grow

It helps in understanding the key product segments and their future

It provides pin point analysis of changing competition dynamics and keeps you ahead of competitors

It helps in making informed business decisions by having complete insights of market and by making in-depth analysis of market segments

TABLE OF CONTENT:

Chapter 1:Genomic Biomarker Market Overview

Chapter 2: Global Economic Impact on Industry

Chapter 3:Genomic Biomarker Market Competition by Manufacturers

Chapter 4: Global Production, Revenue (Value) by Region

Chapter 5: Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6: Global Production, Revenue (Value), Price Trend by Type

Chapter 7: Global Market Analysis by Application

Chapter 8: Manufacturing Cost Analysis

Chapter 9: Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10: Marketing Strategy Analysis, Distributors/Traders

Chapter 11: Genomic Biomarker Market Effect Factors Analysis

Chapter 12: GlobalGenomic Biomarker Market Forecast to 2027

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About Us:

Reports And Markets is part of the Algoro Research Consultants Pvt. Ltd. and offers premium progressive statistical surveying, market research reports, analysis & forecast data for industries and governments around the globe. Are you mastering your market? Do you know what the market potential is for your product, who the market players are and what the growth forecast is? We offer standard global, regional or country specific market research studies for almost every market you can imagine.

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Sanjay Jain

Manager Partner Relations & International Marketing

http://www.reportsandmarkets.com

Ph: +1-352-353-0818 (US)

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