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Archive for the ‘Stem Cell Russia’ Category

Evan Rachel Wood and Chris Evans Model for Gucci; Jennifer Aniston’s $100,000 Beauty Routine

Tuesday, March 6th, 2012

HAIR

Constance Jablonski channels Rosie the Riveter complete with a curly bob and headscarf for Harper's Bazaar Russia. [Fashion Gone Rogue]

Willow Smith dyed her buzz-cut hair neon green. [HuffPo]

Hairstylist Anthony Turner described this season's Kenzo girl backstage at the brand's show yesterday: "Shes met the man of her dreams and hes a rich man. The hair is the day-after-the-night-before," meaning, "She had a little romp on the Upper East Side. [T Magazine]

SKIN

Jennifer Aniston's beauty regimen which includes hair-, skin-, and eyebrow-care, makeup, spray tans, nutrition, and exercise training runs a steep $11,933.97 per month, according to estimates. That's $141,037.97 each year. [ONTD]

Mila Kunis shares her thoughts on growing older with Harpers Bazaar: I will not put a needle in my body unless I have a medical reason. But ask me in 10 years. Right now, Im like, Im going to embrace [aging], but Im probably going to want to have something done. I have no doubt. [PeopleStyleWatch]

Suzanne Somers is testing a newstem cell treatment called cell-assisted lipotransfer, which allows patients to regrow breast tissue. Though the treatment has yet to be approved by the FDA, it could become an alternative for those seeking breast reconstruction without implants. [Jezebel]

U.S. Customs and Border Protection seized a shipment of counterfeit Este Lauder perfumes valued at more than $344,000. [WWD]

Evan Rachel Wood and Chris Evans are the faces of Guccis new scent, Gucci Guilty Intense. [InStyle]

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Ulvang Serves as MS Ambassador, Talks About Change

Saturday, March 3rd, 2012

Norway's celebrated six-time Olympic medalist and world champion, Vegard Ulvang, leads a group at a "Ski with Vegard" event for the top fundraisers on behalf of MS research two days before the 2012 American Birkebeiner in Cable, Wis., on Feb. 23.

All American Birkebeiner coverage is brought to you through the generous support ofConcept2, makers of theSkiErg.

Dr. Ian Duncans first phone call to Vegard Ulvang two years ago met a little dead air. It wasnt that Ulvang, the executive director of the International Ski Federations cross-country committee, didnt want to talk. He couldnt at the time.

The former Norwegian cross-country skiing superstar had the Olympics to tend to.

Last summer, Duncan, a world-renowned National Multiple Sclerosis Society researcher at the University of Wisconsin-Madison, had his second chance with Ulvang on a bike ride.

During one of his stem-cell advisory trips in Norway, Duncan arranged to meet Ulvang and his family. Already chummy with eight-time Olympic gold medalist Bjrn Daehlie, the MS Societys first ambassador at the American Birkebeiner in 2009, Duncan wanted to persuade both Daehlie and his former teammate, Ulvang, to come to Wisconsin for the 2012 Birkie.

Dr. Ian Duncan (l) and Ulvang during the "Ski with Vegard" session, in which top fundraisers for MS had a chance to ski with the Norwegian legend before the 2012 American Birkebeiner.

For Daehlie, the decision to ski North Americas largest ski marathon three years ago was fairly easy. His mother had MS, a chronic and often disabling disease that affects the central nervous system. Daehlie contacted Duncan to help her.

Aside from being a professor, BVMS, PhD and FRCPath, Duncan was also a leading researcher in determining how cell transplants could repair MS-damaged nerve fibers. The connection between the Wisconsin doctor and Daehlie led the retired skier to come to the U.S. on behalf of MS research. Participating in the Birkie was secondary, but it generated a lot of attention.

Three years later, Duncan hoped to attract two Norwegian ski celebrities to the event as MS research ambassadors. After learning that Daehlie couldnt make it, Duncan asked Vegard, who had already agreed to participate in his first Birkie, for some help.

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How Santorum's Scolding Is Dooming His Campaign

Tuesday, February 28th, 2012

In the early summer of 2006, then-Senator Rick Santorum was facing a tough reelection challenge, trailing Pennsylvania's Treasurer Bob Casey by 9 points and struggling to shed his image as a Washington insider. So Santorum launched a statewide, 67-county push, raising twice as much money as Casey, hiring campaign-tested pollsters and ad-makers, and recasting himself an independent-minded fighter.

But when Santorum traveled to the conservative heartland of central Pennsylvania in July to rally supporters, his poll deficit was dropping into the double digits and his larger problem was plain to see: Santorum is a scold. At an Adams County picnic, Santorum delivered the campaign lines crafted to present his independent side, saying he had broken with President Bush on immigration, was critical of Donald Rumsfeld and stood up to the liberal media over welfare and urban policy. But Santorum also spoke to issues he said were a threat to the country: gay rights; embryonic stem cell research; fetal farms. "Scientists," he said, "Go to people who have fatal diseases and say, 'Unless you give us this ability to do this research you know all your kids or all your parents are gonna die! And that's what they tell'm, that's what these researchers, they lie to'm.'"

(PHOTOS: Political Pictures of the Week)

At first Santorum's moral doom-saying just sounds like a slightly wacky play to the extreme wing of the GOP. "Farms" where human fetuses are raised for their organs? They don't exist outside the Huxley-esque imaginings of the far right, so maybe the bill he co-sponsored that year to ban them (later signed into law by George W. Bush) amounted to nothing more than a political stunt. But eventually it becomes clear that Santorum believes America's lax morals are leading to that kind of future. First you teach teenagers about contraception; the next thing you know you are voting in favor of warehouses of fetuses, grown for the benefit of mankind.

In this election cycle, Santorum has tried to shed the image of the former K Street project leader in the Senate who made the move to highly paid consultant after his 18-point loss to Casey in 2006. He's pitching himself as the principled conservative who can stand up to Barack Obama. But in recent weeks voters have begun to see that he thinks they are part of the moral downfall of the country. And his numbers are starting to turn. It's one thing to say Obama or the liberal media are helping take the country to Satan and quite another to say anyone who thinks contraception is "OK" or supports civil unions for gays (never mind gay marriage) is complicit in the Satanic embrace.

(MORE: Arizona GOP Debate: Santorum Finds Himself in the Spotlight and On the Defensive)

For example, 59% of moderate Republicans support gay unions; 63% of independents do. Those voters might be sympathetic to a candidate who opposes civil unions, but they will be strongly against someone who tells them they're position on the issue makes them part of the country's moral collapse. I don't know exactly what Santorum was referring to when he said it, but I think it's safe to say there are a substantial number of Republicans who would take offense at his assertion that their use of contraception leads to "things in the sexual realm that are counter to how things are supposed to be".

On paper, Santorum might be a viable alternative to Romney. In a series of difficult Senate terms, Santorum was more successful than most in reaching across the aisle even as he rose in the GOP hierarchy. But Santorum sees a looming moral apocalypse, abetted by what are now mainstream positions in America. That's not a message that's going to win, even in a GOP primary.

MORE: Rick Santorum's Roll

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CANCER, HOPE AND FAITH: Ill therapist finds strength in God, friends

Saturday, February 25th, 2012

Click photo to enlarge

Don Lichi, a psychologist and president of Emerge Ministries Inc., talks about his battle with bone marrow cancer and how it is affecting his life, during an interview at his office on Jan. 31.

AKRON, Ohio — Don Lichi has always wanted to leave a legacy of a life well-lived.

Exactly what that means has been at the center of his thoughts since November, when he was diagnosed with multiple myeloma (cancer of the plasma cells in the bone marrow).

"At the moment my doctor used the word 'cancer,' my life changed. I have always been a caregiver, but I've had to learn to receive" said Lichi, a prominent psychologist and vice president of Akron, Ohio's Emerge Ministries. "As a man of faith, I am a big believer in healing. I pray for healing.

"If God chooses to take me, I want to be ready for that, too. But I want my life to have been lived in a way that is worthy of being remembered."

A life-changing time

Lichi, 59, was preparing in November for his 12th marathon when he started having excruciating back pain. At first, his doctor thought it might be a slipped disk, but subsequent medical tests revealed it was cancer.

Now, Lichi is undergoing treatment that is preparing him for a stem cell transplant.

"Your life can change on a dime. One day you're moving along, seemingly healthy, with a lot of energy and a fulfilling ministry, and then your world is turned upside down," a visibly emotional Lichi said. "My tears come pretty quickly — sometimes out of pain, sometimes out of the joy of knowing I'm not going through this journey alone, sometimes out of frustration, sometimes out of fear of the unknown — but I am thankful that

I have an inner compass, which is Jesus Christ, to guide me as I go through this storm."

In addition to being on the leadership team at Emerge (a full-service evangelical Christian mental-health outpatient center in Akron, Ohio), Lichi is an adjunct professor at Ashland Theological Seminary and Trinity International University in Illinois. He has spoken about pastoral health, Christian education, parenting, marriage and family issues, at various conferences and workshops, and published several articles on Christian mental health.

He has also done ministry in India, Brazil, Thailand, Ecuador, Germany, Switzerland, Guatemala, Dominican Republic, Haiti, Romania, China, Malaysia, Russia, Hungary and Nicaragua. He has served as counsel to pastors and ministry leaders.

Following own advice

The Rev. Paul Sartarelli, senior pastor at The Chapel, is a friend and ministry partner. Sartarelli was with Lichi when he received the cancer diagnosis and said Lichi has graciously applied the same coping mechanisms to his own life that he has counseled others to use.

"He has really dealt with this well. It's a testimony of who he is. He is a man full of faith. He is a man full of wisdom," Sartarelli said. "As a counselor, he always has great advice, and he is practicing all of the things that he has encouraged others to do over the years. He has been an immeasurable resource to others. Now, it's time for us to come alongside him and be his support system."

The diagnosis Nov. 8 showed the multiple myeloma had attacked a section of his lumbar, putting pressure on his sciatic nerve root and rendering him unable to walk. A December surgery was successful in inflating a balloon to reposition the damaged section of the lower lumbar. Although the procedure gave Lichi some relief, the pain continues.

A recent MRI shows the cancer, which has occupied more than half of his bone marrow, has reached bones of his lumbar, chest, neck and hips. Lichi, who uses a wheelchair, reacted to the news by focusing on what he called "the good news": The cancer does not appear to be in the spinal cord.

God's intervention

Lichi also is focusing on what he calls "God moments" — times when it is clear to him that his source of strength is intervening on his behalf. One of those instances occurred in January, when his primary oncologist prescribed a crucial medication that cost $8,000 out-of-pocket for three weeks of treatment.

"We had no idea how we were going to pay for it, but I trusted God and asked my family and friends to pray with me for whatever God could provide," Lichi said. "An anonymous source called my office one morning, and by the end of the day, the cost of the (first round of) Revlimid was completely covered. I can't tell you how grateful we are to the couple who provided for that and all of the people who have prayed, sent cards, prepared a meal, showed an act of kindness and shared their love."

His treatment includes pain medication, which has been reduced over time, steroids to reduce inflammation and another round of Revlimid. He just completed his fourth round of chemotherapy, which began in November, and needs to complete two more rounds before his bone marrow transplant.

A circle of care

Lichi has found comfort and support in his relationships with his clients, friends and family. His church family at Stow Alliance Fellowship is in that circle of care. He shared his testimony in church to thank congregants and to encourage them to build strong relationships with God and each other.

"When we're shaken as deeply as Don has been with something like cancer, there has to be a foundation within. He is demonstrating that it's the relationship with God, through Jesus Christ, and the relationships with others that enable you to say, 'Even this does not have to overwhelm me,'" said the Rev. John Kitchen, senior pastor at Stow Alliance Fellowship. "Don is showing us that even though we are devastated, even though our very existence may come into question, the facts about who God is and what God continues to provide for us doesn't change."

Before becoming a psychologist, Lichi thought he would be a minister. As a counselor, he finds himself helping pastors, who are among his clients, and considers his work a ministry, or calling of God.

"One of my greatest joys is helping men and women fulfill their call as ministers. It is incredibly fulfilling. Part of what I want to be remembered for is ministering to those who are on the front lines of the faith community," Lichi said. "God has blessed me with the opportunity to help others heal, to embrace the gift of life. I just hope I am remembered for the love that I have tried to give to others."

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Psychologist depends on faith in battle with cancer

Saturday, February 25th, 2012

 

Published Saturday, February 25, 2012 12:19 AM

By COLETTE M. JENKINS

Akron Beacon Journal

AKRON, Ohio -- Don Lichi has always wanted to leave a legacy of a life well-lived.

Exactly what that means has been at the center of his thoughts since November, when he was diagnosed with multiple myeloma (cancer of the plasma cells in the bone marrow).

"At the moment my doctor used the word 'cancer,' my life changed. I have always been a caregiver, but I've had to learn to receive" said Lichi, a prominent psychologist and vice president of Akron, Ohio's Emerge Ministries. "As a man of faith, I am a big believer in healing. I pray for healing.

"If God chooses to take me, I want to be ready for that, too. But I want my life to have been lived in a way that is worthy of being remembered."

Lichi, 59, was preparing in November for his 12th marathon when he started having excruciating back pain. At first, his doctor thought it might be a slipped disk, but subsequent medical tests revealed it was cancer.

Now, Lichi is undergoing treatment that is preparing him for a stem cell transplant.

"Your life can change on a dime. One day you're moving along, seemingly healthy, with a lot of energy and a fulfilling ministry, and then your world is turned upside down," a visibly emotional Lichi said. "My tears come pretty quickly -- sometimes out of pain, sometimes out of the joy of knowing I'm not going through this journey alone, sometimes out of frustration, sometimes out of fear of the unknown -- but I am thankful that I have an inner compass, which is Jesus Christ, to guide me as I go through this storm."

In addition to being on the leadership team at Emerge (a full-service evangelical Christian mental-health outpatient center in Akron, Ohio), Lichi is an adjunct professor at Ashland Theological Seminary and Trinity International University in Illinois.

He has also done ministry in India, Brazil, Thailand, Ecuador, Germany, Switzerland, Guatemala, Dominican Republic, Haiti, Romania, China, Malaysia, Russia, Hungary and Nicaragua. He has served as counsel to pastors and ministry leaders.

The Rev. Paul Sartarelli, senior pastor at The Chapel, is a friend and ministry partner. Sartarelli was with Lichi when he received the cancer diagnosis and said Lichi has graciously applied the same coping mechanisms to his own life that he has counseled others to use.

"He has really dealt with this well. It's a testimony of who he is. He is a man full of faith. He is a man full of wisdom," Sartarelli said. "As a counselor, he always has great advice, and he is practicing all of the things that he has encouraged others to do over the years. He has been an immeasurable resource to others. Now, it's time for us to come alongside him and be his support system."

Lichi is focusing on what he calls "God moments" -- times when it is clear to him that his source of strength is intervening on his behalf. One of those instances occurred in January, when his primary oncologist prescribed a crucial medication that cost $8,000 out-of-pocket for three weeks of treatment.

"We had no idea how we were going to pay for it, but I trusted God and asked my family and friends to pray with me for whatever God could provide," Lichi said. "An anonymous source called my office one morning, and by the end of the day, the cost of the [first round of] Revlimid was completely covered. I can't tell you how grateful we are to the couple who provided for that and all of the people who have prayed, sent cards, prepared a meal, showed an act of kindness and shared their love."



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Psychologist depends on faith in battle with cancer

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Therapist battles cancer with help of others and hope in God

Saturday, February 25th, 2012

AKRON, OHIO — Don Lichi has always wanted to leave a legacy of a life well-lived.

Exactly what that means has been at the centre of his thoughts since November, when he was diagnosed with multiple myeloma (cancer of the plasma cells in the bone marrow).

“At the moment my doctor used the word ‘cancer,’ my life changed. I have always been a caregiver, but I’ve had to learn to receive” said Lichi, a prominent psychologist and vice-president of Akron, Ohio’s Emerge Ministries. “As a man of faith, I am a big believer in healing. I pray for healing.

“If God chooses to take me, I want to be ready for that, too. But I want my life to have been lived in a way that is worthy of being remembered.”

Lichi, 59, was preparing in November for his 12th marathon when he started having excruciating back pain. At first, his doctor thought it might be a slipped disc, but subsequent medical tests revealed it was cancer.

Now, Lichi is undergoing treatment that is preparing him for a stem cell transplant.

“Your life can change on a dime. One day you’re moving along, seemingly healthy, with a lot of energy and a fulfilling ministry, and then your world is turned upside down,” a visibly emotional Lichi said. “My tears come pretty quickly — sometimes out of pain, sometimes out of the joy of knowing I’m not going through this journey alone, sometimes out of frustration, sometimes out of fear of the unknown — but I am thankful that I have an inner compass, which is Jesus Christ, to guide me as I go through this storm.”

In addition to being on the leadership team at Emerge (a full-service evangelical Christian mental-health outpatient centre in Akron, Ohio), Lichi is an adjunct professor at Ashland Theological Seminary and Trinity International University in Illinois. He has spoken about pastoral health, Christian education, parenting, marriage and family issues, at various conferences and workshops, and published several articles on Christian mental health.

He has also done ministry in India, Brazil, Thailand, Ecuador, Germany, Switzerland, Guatemala, Dominican Republic, Haiti, Romania, China, Malaysia, Russia, Hungary and Nicaragua. He has served as counsel to pastors and ministry leaders.

The Rev. Paul Sartarelli, senior pastor at The Chapel, is a friend and ministry partner. Sartarelli was with Lichi when he received the cancer diagnosis and said Lichi has graciously applied the same coping mechanisms to his own life that he has counselled others to use.

“He has really dealt with this well. It’s a testimony of who he is. He is a man full of faith. He is a man full of wisdom,” Sartarelli said. “As a counsellor, he always has great advice, and he is practising all of the things that he has encouraged others to do over the years. He has been an immeasurable resource to others. Now, it’s time for us to come alongside him and be his support system.”

The diagnosis Nov. 8 showed the multiple myeloma had attacked a section of his lumbar, putting pressure on his sciatic nerve root and rendering him unable to walk. A December surgery was successful in inflating a balloon to reposition the damaged section of the lower lumbar. Although the procedure gave Lichi some relief, the pain continues.

A recent MRI shows the cancer, which has occupied more than half of his bone marrow, has reached bones of his lumbar, chest, neck and hips. Lichi, who uses a wheelchair, reacted to the news by focusing on what he called “the good news”: The cancer does not appear to be in the spinal cord.

Lichi also is focusing on what he calls “God moments” — times when it is clear to him that his source of strength is intervening on his behalf. One of those instances occurred in January, when his primary oncologist prescribed a crucial medication that cost $8,000 out of pocket for three weeks of treatment.

“We had no idea how we were going to pay for it, but I trusted God and asked my family and friends to pray with me for whatever God could provide,” Lichi said. “An anonymous source called my office one morning, and by the end of the day, the cost of the (first round of) Revlimid was completely covered. I can’t tell you how grateful we are to the couple who provided for that and all of the people who have prayed, sent cards, prepared a meal, showed an act of kindness and shared their love.”

His treatment includes pain medication, which has been reduced over time, steroids to reduce inflammation and another round of Revlimid. He just completed his fourth round of chemotherapy, which began in November, and needs to complete two more rounds before his bone marrow transplant.

He and his wife, Marcie, were scheduled to go to University Hospital this week for in-patient treatment orientation, which takes a minimum of four hours. The transplant involves using high-dose chemotherapy with a transfusion of stem cells previously collected from Lichi, which will replace the diseased marrow.

Although Lichi’s journey since November has been tempestuous, he has been back at work, counselling at Emerge, since January. John Palmer, president of Emerge, said that while he expected Lichi to return to work, he was pleasantly surprised he returned so soon.

“Don is not ignoring the facts of his situation. He acknowledges what is going on with the cancer, but at the same time, he acknowledges his hope in God. He is the kind of person who is not going to sit around when he can do something useful,” Palmer said.

“He’s an amazing person who has such deep compassion for people, and he’s courageous in continuing to help people in such a joyful way while going through his own crisis.”

Lichi has found comfort and support in his relationships with his clients, friends and family. His church family at Stow Alliance Fellowship is in that circle of care. He shared his testimony in church to thank congregants and to encourage them to build strong relationships with God and each other.

“When we’re shaken as deeply as Don has been with something like cancer, there has to be a foundation within. He is demonstrating that it’s the relationship with God, through Jesus Christ, and the relationships with others that enable you to say, ‘Even this does not have to overwhelm me,’” said the Rev. John Kitchen, senior pastor at Stow Alliance Fellowship. “Don is showing us that even though we are devastated, even though our very existence may come into question, the facts about who God is and what God continues to provide for us doesn’t change.”

Before becoming a psychologist, Lichi thought he would be a minister. As a counsellor, he finds himself helping pastors, who are among his clients, and considers his work a ministry, or calling of God.

“One of my greatest joys is helping men and women fulfil their call as ministers. It is incredibly fulfilling. Part of what I want to be remembered for is ministering to those who are on the front lines of the faith community,” Lichi said. “God has blessed me with the opportunity to help others heal, to embrace the gift of life. I just hope I am remembered for the love that I have tried to give to others.”

Akron Beacon Journal

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Renato Dulbecco dies at 97; 1975 Nobel Prize winner in medicine

Wednesday, February 22nd, 2012

Dr. Renato Dulbecco, an Italian American virologist who shared the 1975 Nobel Prize in physiology or medicine for demonstrating how certain types of viruses invade mammalian cells to cause cancer, died of natural causes Sunday at his home in La Jolla. He was 97.

Dulbecco developed a method for measuring the quantity of virus in animal cells in tissue culture, a finding that greatly facilitated the study of such viruses and paved the way for the development of the Sabin polio vaccine. He was a faculty member at Caltech from 1949 to 1963 before moving to the Salk Institute for Biological Studies in La Jolla. He later served as president of the institute.

FOR THE RECORD:
Renato Dulbecco: A news obituary in the Feb. 21 LATExtra section of Nobel Prize-winning virologist Renato Dulbecco misspelled the first name of Italian anatomist Giuseppe Levi as Giuseppi. —

Dulbecco was also one of the first proponents of the human genome project, which many researchers initially thought would be both excessively expensive and relatively useless but which has since proved invaluable in biological research.

"Renato was one of the most brilliant scientific minds of our generation," current Salk Institute President William R. Brody said in a statement. "His contributions have truly made this a better world for all of us."

It has been known since the early 1900s that certain viruses can cause tumors in animals. The best-known example was the Rous sarcoma virus, which causes cancer in chickens. But it was not clear how the viruses produced this effect and what proportion of human cancers might be attributed to them.

In experiments carried out at Caltech in the 1950s, Dulbecco showed that a viral infection can have two outcomes: the virus can multiply inside the cell, killing the cell and releasing thousands of new viruses into the host animal; or it could alter the cell so that the cell would continue to divide and grow indefinitely, a process called transformation.

In the latter case, no new virus particles appear and the infecting virus seemingly disappears.

Through an elegant series of experiments, Dulbecco showed that the DNA from the polyoma virus became integrated into the DNA of the host cell, where it was replicated intact every time the cell replicated. Moreover, the viral DNA served as the blueprint for a small number of proteins that subverted cellular machinery, causing the cells to reproduce repeatedly — the hallmark of tumor formation.

Additionally, this feat was achieved before it was possible to sequence the DNA of either viruses or animal cells.

For his achievement, Dulbecco shared the 1975 Nobel Prize with Howard Temin and David Baltimore, who demonstrated the existence of an enzyme — reverse transcriptase — that allowed RNA viruses to integrate their genes into a host cell in the same fashion as the DNA viruses studied by Dulbecco. Both were former students of his.

In his Nobel address, Dulbecco called for increased restrictions on tobacco use because of its carcinogenic potential and urged governments to make greater efforts to limit the introduction of dangerous chemicals.

"While we spend our life asking questions about the nature of cancer and ways to prevent or cure it," he said, "society merrily produces oncogenic substances and permeates the environment with them."

Renato Dulbecco was born Feb. 22, 1914, in Catanzaro, Italy, the son of a civil engineer. He enrolled at the University of Turin, where he had meant to study physics and chemistry but soon became interested in biology instead.

He received his medical degree in 1936 and during World War II served in France and Russia, where he was injured in 1942 during a major Russian offensive along the Don River.

After several months of hospitalization, he returned home, hiding out in a small village near Turin when German forces occupied Italy after Mussolini's fall. He served as a medical officer for partisan forces resisting the occupation.

In medical school, Dulbecco had worked in the laboratory of noted anatomist Giuseppi Levi, along with fellow students Salvador Luria and Rita Levi-Montalcini, both of whom also became Nobel laureates. In 1946, Luria invited Dulbecco to join his small laboratory at the Indiana University and Dulbecco immigrated the following year, becoming a U.S. citizen in 1953. At IU, he shared bench space with James Watson, another eventual Nobel laureate.

Dulbecco was working with bacteriophage, small viruses that invade only bacteria cells. He showed that bacteriophage that had been disabled by exposure to ultraviolet light could be reactivated by exposing them to bursts of white light.

That work attracted the attention of microbiologist Max Delbruck, who invited Dulbecco to join him at Caltech. In the summer of 1949, Dulbecco and his then-wife, the former Giuseppina Salvo, drove an old car cross-country. He wrote in his Nobel autobiography that he was struck by "the beauty and immensity of the U.S.A. and the kindness of its people" and vowed to continue to live here forever.

While at Caltech, Dulbecco adapted a technique he had used with bacteriophage to count the number of virus particles that are present in a tissue sample. Dubbed the plaque assay technique, the assay relies on the fact that viruses added to a culture of cells kill small areas of cells, producing clear circles that can be counted.

This technique enabled researchers for the first time to measure the concentrations of virus in a sample and was crucial to Albert Sabin's work in inventing an attenuated virus polio vaccine. Dulbecco, in fact, originally isolated the mutant polio virus used by Sabin in his vaccine.

In 1962, Dulbecco became a founding member of the Salk Institute, where he remained for the rest of his career. He also spent time at the Imperial Cancer Fund Research Laboratories in London, where he worked on human cancer viruses, although he remained on the staff at Salk. In his later years, he researched breast cancer and concluded that breast cancer stem cells gone awry might be responsible for certain types of breast tumors.

In 1988, he became interim president at Salk, a position that soon became permanent. He held the post until he returned to his laboratory research in 1992.

During the 1980s, Dulbecco had argued passionately in favor of a human genome project. After his retirement as Salk president he was asked by the Italian National Research Council to develop an Italian human genome project, and he spent about half his time each year in that country. The project was abandoned after five years, however, because of lack of funding and facilities.

Dulbecco was a classically trained pianist who was passionate about music and performed opera. He was also a dedicated do-it-yourself handyman and once told The Times, "If I can get a week off to work on the house, that's the best vacation I can get." He remodeled his kitchen and added about 1,000 square feet of space to his home in La Jolla, performing all the work — including plumbing and electrical — himself.

Dulbecco is survived by his second wife, Maureen, whom he married in 1962; a brother, two daughters and four grandchildren. A son predeceased him.

Maugh is a former Los Angeles Times staff writer.

news.obits@latimes.com

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Renato Dulbecco dies at 97; 1975 Nobel Prize winner in medicine

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Insights Into MI6: Stem Cell Transplantation – Video

Tuesday, February 21st, 2012

08-02-2012 23:17 NicholasAnderson.info Nicholas Anderson, Author of "NOC British Secret Operations" interviewed by Joseph Dowdy. stem cell transplantation... can't say diseases to get hopes up. oversaw exfiltration of doctor who is an expert at stem cell transplantation. not an expert or doctor, but can speak from experience. much of this may bother others. there is an assumption one belief is correct and others are wrong. stem cells are human and animal organisms derived from embryos. they can renew themselves in others bodys/cells/tissues. they are not factory assembled. they are coming from aborted tissue that would be thrown away. in the soviet union, they experimented on them. again, author does not know all about stem cells. speak to your doctor and do your own research. for most basic info on the doctor from the soviet union, see the book. was this post cold war debriefing? was he a scientist who knew a lot? no. he defected in mid-70s. the west/us/uk milked him for info. they did nothing with that info. he returned to the new russia after the collapse and started again. what has he been doing since? is the russian medicine better?? yes, it's more advanced or the west has simply got their advancements from russia. this is like a replacement battery for tissue/cells/body; it must be recharged. it does offer terminally ill chance to live longer; not a medical diagnosis. if people know enough about stem cells, they probably know what it is... it's good for regenerating tissue without ...

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Russian Press – Behind the Headlines, February 20

Monday, February 20th, 2012

Moskovskiye Novosti

Church Calls for Ban on Stem Cell Research

The Russian Orthodox Church has called for recognizing fetuses as human life and for banning medical research that involves biological material procured from abortion procedures.

The church has sent a series of amendments to the cell technology bill, which iscurrently in the works, to Healthcare Minister Tatyana Golikova in the hope that “the ministry will heed its opinion.” “We, in turn, are ready for dialogue and discussion on each proposal,” said Bishop Panteleimon, head of the the Synodal Department for Church Charity and Social Ministry.

Incidentally, the clerics cite “enlightened” European policies on this issue. In October 2011, the European Court of Justice outlawed the patenting of stem cell research that destroys a human embryo as immoral. Russia’s Healthcare Ministry supported that decision and said the cell technology bill they were working on embraced similar ethical principles. Deputy Minister Veronika Skvortsova said the new bill would ban the use of a human fetus, embryo or gamete in preparing cell lines.

According to Father Panteleimon, this means that the government is ready to agree that a fertilized ovum constitutes a person. Therefore, it would only remain to legalize this statement. That would make it possible to refer to an embryo as a “child,” which in turn would make the 1959 Children’s Rights declaration applicable to the embryo, thus guaranteeing the “child” legal protection “before and after birth.”

One proposal would include church officials on the ministry’s expert council on biomedical ethics. The church has had a similar council since 1998.

“The ministry’s bill cites advanced cell technology that is not widely used in Russia,” a church official said. “At the same time, there are simpler technologies which also use fetal cells as biological material, and these are quite widespread.”

The letter sent to Minister Golikova mentions valid patents for using fetal cells in anti-aging treatments, mesotherapy and fetal tissue implants.

The bill, drafted by the Ministry of Healthcare, is currently in the public discussion stage, and could be submitted to the lower house this spring. Given current legislative trends, the church may well expect that its proposals will be heeded. However, Russian scientists involved in stem cell research fear that the bill would entirely halt research in this area.

According to Sergei Kiselyov from the Human Stem Cells Institute, very few cell technologies are actually used in medicine. The bill would drastically limit the current research and could affect projects that are already underway. This would lead to Russia’s lagging even further behind Western biotechnology, he said.

Kommersant

Russia Joins OECD Convention Against Bribery

The Russian Foreign Ministry notified the Organization for Economic Cooperation and Development (OECD) on Friday that Russia has joined the OECD Convention on Combating Bribery of Foreign Public Officials in International Business Transactions. Experts believe that joining the convention will stimulate the fight against corruption. Russia will be the 39th state party to the convention as of April 17.

The State Duma ratified the convention on January 13, 2012, and President Dmitry Medvedev signed it into law on February 1. Medvedev said at a judiciary meeting, “Accession will harmonize our legal system with international standards in the fight against corruption.”

“We have not joined this convention to please anybody,” First Deputy Foreign Minister Andrei Denisov clarified. “Joining is important in terms of our internal anti-corruption policy.”

Denisov added that ratifying the convention, a three-year process, is a condition for OECD accession. Russia, he said, will seek to join the organization in 2013, but the country will have to ratify 160 other conventions and instruments in 22 categories, including the introduction of international standards for economic statistics. Joining the anti-bribery convention requires Russia to pay annual dues of about 100,000 euros per year to the OECD Working Group on Bribery in International Business.

The convention was signed in 1997 and entered into force in February 1999. Most European countries are members, as are some Latin American countries and the United States. The main obligation for the states parties is to track and prosecute their citizens for bribery or attempted bribery of foreign officials and to track foreign officials on their territories who take bribes. The convention recommends not only criminalizing these acts, but also blacklisting the companies found guilty of bribing foreign public officials from tenders for government contracts. The convention discourages the practice of allowing income tax deductions for bribes to officials of foreign states: some companies in developing countries having been implicated in this practice. The convention aims to prevent parties from adding to corruption not only within their borders, but also beyond. However, fewer than 20% of participating countries actively apply the convention's provisions, according to a 2011 Transparency International report.

Even before ratifying the convention, Russia adopted a series of measures to fulfill it. In April 2011, Dmitry Medvedev's anti-corruption package introduced amendments to the Criminal Code, including multiple penalties for giving and receiving bribes, as well as mediation. Foreign officials as well as companies that give bribes to foreign officials or officials of international public organizations will be held liable.

Vladimir Yuzhakov, director of the Department for Administrative Reform at the Center for Strategic Studies, said that the practice of applying the convention will provide additional incentives to fight corruption in the country in general. Yuzhakov expects that the convention will require further steps in developing anti-corruption legislation – in particular, the introduction of more stringent procedures for investigating cases of bribery of foreign public officials.

RIA Novosti is not responsible for the content of outside sources.

 

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Gazette.Net: From Russia and the Redskins to fighting TB in Rockville

Monday, February 13th, 2012

Dan Gross/The Gazette While working for the Washington Redskins, ?I learned a lot about the management of a large team and a large budget,? says Marty Zug, CFO of Sequella in Rockville.

With career stops that included Russia and the Washington Redskins, it took Marty Zug a while to land at Rockville biotech Sequella.

But he has remained there for more than seven years, his longest stint with one employer by far.

Carol A. Nacy, CEO and chairwoman of Sequella, for one, is happy about that.

Zug, CFO at the biotech that is developing drugs to combat infectious diseases such as tuberculosis and bacteria such as Helicobacter pylori, has become a force in lobbying for industry issues such as more funding for the state?s biotech investment tax credit program. That program has helped infuse Sequella and other biotechs with millions of dollars in much-needed capital.

?He?s been a huge addition to our company,? said Nacy, who co-founded Sequella with Chief Scientific Officer Leo Einck in 1997. ?He?s delightful to work with, smart, industrious. I?d like to clone him.?

Many CFOs can almost be exclusively number-crunchers. Not Zug. He makes friends easily and is not the kind of lobbyist who forcefully hammers home points, colleagues say.

?He really enjoys other people,? Nacy said. ?He gets along with legislators and other people in the biotech community. ... In Annapolis, he takes the time to explain the problem in clear terms.?

Steel roots

Zug grew up in Bethlehem, Pa., where his grandfather and uncle worked in the steel mills. At Lehigh University, he majored in economics and Russian studies, graduating summa cum laude. He spent his junior year studying in Moscow at the Russian Academy of Economics and became fluent in Russian.

?I took a trip there in 1987 when glasnost was one of the buzzwords,? said Zug, 42. ?I became fascinated with the country and the changes going on. I had always been interested in world affairs.?

After graduating in 1992, he moved to Russia without having a firm job offer.

?It wasn?t hard to find a job,? Zug said.

He ended up working as a project manager for Sea-Land CIS Logistics in Moscow and then as an investment officer with International Finance Corp., which has offices in Washington, D.C., and Moscow. With the latter company, Zug said, he structured and closed financing for deals worth more than $39 million in equity and $75 million in debt, and was part of the banking team that closed the first syndicated loan in Russia and the largest private financing of a Russian company in 1995.

He left International Finance in 1996 to earn a master?s of business administration at Dartmouth College in Hanover, N.H., graduating as an Edward Tuck Scholar in the top 15 percent of his class. Then came stints with Arthur Andersen in Washington, Snyder Communications in Bethesda and the Redskins.

As director of financial projects at Snyder Communications, Zug managed Wall Street corporate presentations, among other duties. The marketing firm was run by current Redskins owner Daniel M. Snyder of Potomac; it was sold to French advertising group Havas for more than $2 billion in 2000.

As a vice president with the Redskins for two years, Zug supervised a staff of 20 with a budget of more than $3 million, running the ticket office, as well as premium seating and stadium business.

?I learned a lot about the management of a large team and a large budget,? Zug said. ?I already was fairly strong in finance but got more exposure in sales and marketing.?

He then took a year off to help raise a newborn, working as an independent consultant on projects that included a $6.5 million sale of a Bahamian hotel. He also managed the Washington area?s bid for the 2008 Super Bowl. The NFL championship game typically is played in a warm-weather city or one with a domed stadium, but the local bid was strong enough to make Washington a finalist, with the game ending up in Arizona.

Russian pays off at Sequella

With Sequella, knowing Russian and having done business in that country paid dividends when Zug last year negotiated an out-license agreement with a Russian venture fund to develop a treatment for tuberculosis in the Russian Federation and neighboring countries. That agreement could be worth as much as $50 million.

Sequella?s lead drug, SQ109, targets tuberculosis and multidrug-resistant tuberculosis. The company also has significant activity working with Helicobacter pylori, which causes gastric ulcers and can help cause gastric cancer. Sequella is starting a phase 2a clinical trial for SQ109 in H. pylori at sites in Texas.

Zug, a member of the Tech Council of Maryland?s Government Relations Committee, has been a leader in growing the state?s biotech investment tax credit program, which has been run by the Department of Business and Economic Development since 2006. The program allows investors in qualifying companies to claim credits against state income taxes, while biotechs try to leverage the capital for more investment.

One of the tech council?s goals is to persuade lawmakers to increase the fund from $8 million annually, Zug said. The credits usually run out within the first hour or so that the program takes effect each July 1.

?We want to make sure this program remains a shining star and an example for other states? Zug said. ?It?s a great market-driven program that works.?

Other states, including Virginia, have implemented similar programs, he said. Last year, Rep. Christopher Van Hollen Jr. (D-Dist. 8) of Kensington sponsored the Innovative Technologies Investment Incentive Act, modeled on the Maryland tax credit program that would have allowed an investor in a biotech or high-tech company with fewer than 500 employees to claim a federal tax credit of 25 percent. But the legislation attracted only seven co-sponsors, including only one from Maryland, Rep. C.A. Dutch Ruppersberger (D-Dist. 2) of Cockeysville, and did not pass.

Besides lobbying for more tax credit funds in this year?s legislative session, which started in January and runs through April 9, Zug supports bills filed in both the House and Senate that would require that at least one-third of grants or loans awarded each year by the state?s Stem Cell Research Fund be awarded to for-profit companies with headquarters in Maryland. Most stem cell awards now go to either Johns Hopkins University or the University of Maryland, Baltimore, although in fiscal 2011, about 28 percent of awards went to collaborations with for-profit companies, including some in other states, according to a state legislative report.

Much of the success of the state?s biotech community?s efforts in Annapolis can be attributed to Zug, said Brian Levine, vice president of government relations with the tech council in Rockville, who has worked closely with him.

?He is a good leader, very organized and always provides thoughtful ideas,? Levine said.

As venture capital has dried up, programs such as the tax credit have become that much more important to growing biotechs, Zug said. Biotechs are fortunate to have the support that Maryland and entities such as the National Institutes of Health lend, he said. Sequella usually submits about eight grant applications per year to NIH, which funds two or three, Zug said.

?You will be hard-pressed to find another state doing as much as Maryland,? he said.

Marty Zug

Age: 42.

Position: CFO, Sequella, Rockville.

Previous position: Vice president, Washington Redskins.

Education: Master?s of business administration, Dartmouth College, Edward Tuck Scholar; bachelor?s in finance and Russian studies, Lehigh University.

Residence: McLean, Va.

Family: Wife, Becky, and three children.

Hobbies: Travel, family activities.

kshay@gazette.net

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This Week in Modern Pathology

Wednesday, February 8th, 2012

In Modern Pathology this week, researchers from the Seoul National University in South Korea report on the association between the patterns of promoter CpG island methylation of breast cancer subtypes and cancer stem cell phenotypes. The team analyzed methylation status of 15 promoter CpG island loci involved in breast cancer progression, and determined their cancer stem cell phenotypes. They found that "the number of CpG island loci methylated differed significantly between subtypes, and was highest in the luminal-HER2 subtype and lowest in the basal-like subtype. Methylation frequencies and levels in 12 of the 15 genes differed significantly between subtypes, and the basal-like subtype had significantly lower methylation frequencies and levels in nine of the genes than the other subtypes." These findings suggest that breast cancer subtypes have distinct methylation patterns and that these patterns are associated with different stem cell phenotypes, the authors add.

Also in Modern Pathology, a team of French researchers elucidates the role of the mTOR pathway in leiomyosarcomas and pleomorphic sarcomas. The team assessed PTEN level and protein expression as well as the activation of downstream pathways, in a large series of sarcomas. They observed PTEN partial genomic loss in 46 percent of the tumors and a loss of protein expression in up to 68 percent of the tumors. "PTEN mutations were rare, with only 4 point mutations in the 65 samples studied," the authors write. "Subsequent activation of AKT and mTOR pathways was only observed in 2 out of 3 of PTEN-deleted tumors. On the other hand, RICTOR, a major component of the mTOR complex 2, was significantly overexpressed in well-differentiated leiomyosarcomas." The results suggest a link between RICTOR over-expression and leiomyosarcomas oncogenesis, the researchers add.

Finally in Modern Pathology this week, Macher-Goeppinger et al. report on the molecular heterogeneity of TFE3 activation in renal cell carcinomas. The team examined TFE3 expression and underlying genetic alterations in a series of renal cell carcinomas with long-term follow-up information. They found that five out of a total 876 tumors had TFE3 translocations, but that 9 percent of all renal cell carcinoma samples showed some degree of TFE3 reactivity. "Interestingly, these cases were associated with high nuclear grade, greater tumor extent and metastatic disease as well as an unfavorable patient outcome on uni- and multivariate analysis," the authors write. "Fluorescence in situ hybridisation revealed TFE3 amplifications as an additional, novel mechanism leading to increased TFE3 expression levels."

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Iranian leader dismisses sanctions, warns U.S. against war

Saturday, February 4th, 2012

WASHINGTON — Dismissing economic sanctions that are beginning to bite, Iran's supreme leader said Friday that his country wouldn't bow to Western demands that it stop enriching uranium and warned that a war over its nuclear program would be "10 times more harmful" to the United States.

"The Americans and others should, and do, know that we have our own threats to confront the military threats and oil sanctions and when necessary. We will make use of them at the right time," declared Ayatollah Ali Khamenei, according to an English transcript of his remarks posted on his official website.

Khamenei delivered the fiery, nationally broadcast sermon at Friday prayers at Tehran University amid rising tensions over Iran's nuclear program, which Tehran contends is producing uranium fuel for civilian nuclear reactors and the United States and other powers charge is secretly developing a nuclear warhead.

The Obama administration is growing increasingly concerned that Israel — dubious that sanctions will force Iran to halt its program before it attains the ability to build a bomb — will strike Iranian nuclear facilities in the coming months. The White House also has repeatedly refused to rule out U.S. military action as a last resort.

While Khamenei's speech may have been designed to warn off the United States and Israel, his harsh tone may primarily have been aimed at rallying domestic support for his unpopular regime, especially as Iran marks the anniversary of the 1979 Islamic revolution. The country also is heading into parliamentary elections next month with the sanctions stoking inflation, choking off hard currency supplies and forcing a devaluation of the Iranian rial.

Moreover, nothing that Khamenei said dampened expectations among U.S. and European officials and experts that Tehran may soon accept an invitation to renew international negotiations on its nuclear program — something that Iranian officials insist they favor.

"Nothing he (Khamenei) said is terribly surprising or different than what he's said in the past," said Robin Wright of the U.S. Institute of Peace. "I expect the Iranians to go back to the table."

In his rare public sermon, Khamenei declared that Iran won't heed U.N. demands to suspend uranium enrichment despite four rounds of U.N. sanctions and separate measures by the United States and the European Union designed to choke off Iranian oil sales, the country's main revenue source.

"The goal of these sanctions is to force Iran to back down, but Iran will not back down," Khamenei declared.

U.S. officials "constantly make threats, saying all options are on the table, that is to say even a military attack. This military threat is harmful to America and an actual war would be 10 times more harmful to America," he said.

Khamenei didn't elaborate on how Iran might respond. But Iran has threatened to blockade the Strait of Hormuz — the narrow waterway at the southern end of the Persian Gulf through which 40 percent of the world's seaborne oil travels — a development that could send world oil prices skyrocketing, dealing a major blow to the U.S. economy just as it's recovering from the Great Recession.

Iran also could launch ballistic missile attacks against U.S. forces in the region and Israel, and sponsor terrorist strikes against U.S. and European targets around the world.

The Iranian leader also had harsh words for Israel, saying that "from now on, whenever a nation or a group fights and confronts the Zionist regime, we will support and help it, and we are not at all afraid of saying this."

Khamenei said that the sanctions were imposed not only to force Iran to halt its nuclear program, but to "punish the Islamic Republic and the Iranian nation for being committed to Islam."

"But the truth is, these sanctions will benefit us," he continued, saying that a U.N. arms embargo has compelled Iran to develop its own military industries and that other sanctions have led the country to develop its expertise in nuclear physics, "stem cell research, aerospace and launching satellites into space."

His speech came the same day as Iran announced that it had successfully launched a small satellite into orbit.

The United States and the European Union are hoping that the sanctions will force Iran to accept an offer to negotiate a suspension of its nuclear program and safeguards to ensure its use for civilian purposes in return for trade, financial assistance and other benefits.

The last round of talks collapsed just over a year ago. The European Union late last year invited Iran to resume the negotiations with the United States, China, Russia, France, Britain and Germany.

Iranian officials say they are open to resuming the talks, but U.S. and EU officials insist that Tehran must agree in writing to resume negotiations without preconditions.

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Iranian leader dismisses sanctions, warns U.S. against war

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Adult Stem Cells Saved My Life Campaign – Video

Saturday, December 10th, 2011

Stemcellresearchfacts.com was launched at an event in the Kansas City area which brought together a group of very grateful adult stem cell transplant recipients.

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Obama to cut US wiretapping? – Video

Tuesday, November 29th, 2011

It has taken President Obama less than a week to make a u-turn on such workings of the Bush Administration like stem cell research and exhaust emissions. Civil rights organisations hope cuts to wiretapping will be next.

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Stem sell banking gains popularity – Video

Friday, November 25th, 2011

Replacing worn-out parts of your body could soon be as easy as changing broken car parts. Some people pay thousands of dollars to bank their stem cells, dreaming to stay healthy forever.

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Human cloning gets green light in Australia – Video

Thursday, November 24th, 2011

The Australian government has issued the worlds first licence for the cloning of humans, reports the Reuters news agency. Sydney IVF has been given permission to clone human embryos in order to harvest stem cells. Because these cells have the ability to transform into cells of all types, they are potentially invaluable in the treatment of some diseases.

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RESOURCE BASED ECONOMY -GENETICS msnbc video High hopes for heart stem cell treatment. – Video

Thursday, November 17th, 2011

NO LONGER FUTURE TECH OR FANTASY IT IS IN PATIENT TRIALS RIGHT NOW--TECHNOLOGY IS EXPONETIALLY EXPLODEING ALL AROUND US--THE RESOURCE BASED ECONOMY EMBRACES TECHNOLOGY.---RESEARCH EITHER THE ZEITGEIST OR THE VENOUS PROJECT TO LEARN MORE ABOUT A RESOURCE BASED ECONOMY

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RESOURCE BASED ECONOMY -GENETICS msnbc video High hopes for heart stem cell treatment. - Video

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Obama’s stem cell move gives hope to McKinney quadriplegics – Video

Monday, October 24th, 2011

This was aired March 9, 2009. Traci Bryan and I had both been traveling to Moscow, Russia for Stem Cell Treatment

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Walking Improvements between stem cell treatments – Video

Saturday, October 22nd, 2011

Comparison of Eric's walking from October 2009 to November 2010. We took the video prior to his first stem cell treatment in Russia and his second stem cell treatment in Kazakhstan.

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Walking Improvements between stem cell treatments - Video

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Stem Cell Treatment #1 Video 9 – Video

Friday, October 21st, 2011

October 2009. Video of inside of Red Square close to the hotel we stayed at.

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