from the knowing-too-much dept
The cost of sequencing every DNA "letter" in a human genome has fallen faster than Moore's Law, from around $100 million in 2001, to under $1,000 today (although some say the overall cost in a clinical context is higher). This brings with it the prospect of routinely carrying out full-genome sequencing for everyone. That's precisely what Matt Hancock, the UK's Health Secretary, has said he wants to see as a part of the country's National Health Service (NHS), reported here by The Telegraph:
"My ambition is that eventually every child will be able to receive whole genome sequencing along with the heel prick test [a basic test for genetic conditions]," he told the conference.
"We will give every child the best possible start in life by ensuring they get the best possible medical care as soon as they enter the world. Predictive, preventative, personalised healthcare -- that is the future of the NHS -- and whole genome sequencing and genomics is going to play a huge part in that," he said.
Creating a massive database of near-complete genomes will probably ring alarm bells for Techdirt readers. Just recently, US police have started obtaining warrants to search entire DNA databases, even of people who opted out of allowing law enforcement to access their genomic data. That's despite the fact that "touch DNA" is mostly guesswork, and that crime lab testing is beset with problems. Moreover, a mistaken belief that DNA is infallible can lead to innocent people being charged with serious crimes like murder.
It's true that DNA can be a very powerful tool for solving crimes by finding distant matches in publicly-available genetic data, and then constructing family trees to narrow down the possible suspects. But that fact also exposes why routinely obtaining someone's DNA, as Hancock proposes for newborns in the UK, has an important impact on anyone related to the person whose whole genome is sequenced.
Even when DNA databases of a complete population are not set up for the purposes of mass surveillance, as Kuwait proposed (but then scaled back), and as China is implementing in Xinjiang as a way of controlling the local Uyghur population, there are other serious issues that need to be considered.
For example, the Telegraph article notes that full-genome sequencing of newborns means "parents could choose to be alerted to the fact their child faced heightened risks of specific diseases, and allow the NHS to offer more tailored treatment." But would parents necessarily welcome knowing that their child is more likely than the average individual to develop some serious genetic condition at some point in their lives? And what about if that condition had no treatment at present? What is gained by knowing of the risk? Might parents, and later the affected children themselves, find that knowledge almost too much to bear -- a genetic sword of Damocles hanging over them all their lives? Equally, parents might feel guilty if they don't ask for this information, which could allow for earlier treatment of diseases.
There's no doubt that full-genome sequencing will have a major impact on medicine in the decades to come, and offers the hope of more targeted and more effective medicines for many conditions. But for the benefits to be realized, doctors and genetic counselors will need to find effective ways to talk to people about what the detailed but probabilistic information revealed by their complete genomes will mean for their future health and treatments. Only then can we make informed decisions that enhance our well-being and happiness.
Follow me @glynmoody on Twitter, Diaspora, or Mastodon.
Filed Under: babies, dna, health minister, matt hancock, nhs, privacy, surveillance, uk, uk health secretary
- Utilizing your free, preventative healthcare coverage - KELOLAND.com - February 18th, 2024
- Preventive Pros: the Podcast - Department of Population and Public Health Sciences - University of Southern California - February 18th, 2024
- Heart health awareness and preventative care with Jen Lewis on Coast Live - News 3 WTKR Norfolk - February 18th, 2024
- Heart disease risk factors in women highlight need for increased awareness, prevention - American Heart Association - February 18th, 2024
- Preventive health care benefits | Opinion | thecabin.net - Log Cabin Democrat - February 18th, 2024
- Menopause and migraines: New findings point to power of prevention - Medical Xpress - February 18th, 2024
- How Young Is Too Young For Preventative Skincare? Here's What Experts Want You To Know - Health.com - February 18th, 2024
- Potential prevention of rheumatoid arthritis with injection? Clinical study brings hope for millions - WION - February 18th, 2024
- Heart disease risk factors in women highlight need for increased awareness, prevention - Medical Xpress - February 18th, 2024
- Stay on top of your fur baby's health: the importance of scheduling routine vet visits - FoxReno.com - May 17th, 2023
- Preventive healthcare - May 9th, 2023
- What Is Preventive Health and Why Is It Important? - May 9th, 2023
- What Is Preventive Medicine & Why Do We Need It? | AUC - February 16th, 2023
- Preventive Medicine | Journal | ScienceDirect.com by Elsevier - December 3rd, 2022
- Migraine - Diagnosis and treatment - Mayo Clinic - December 3rd, 2022
- Functional Medicine of Idaho | Preventative Root Cause Medicine - December 3rd, 2022
- These 2 Staten Island nurses believe IV hydration drips and vitamin shots are key to long-term health - SILive.com - December 3rd, 2022
- CNBCTV-18 and IIM-K's India@2047 Leadership Series: Challenges and opportunities in the fintech and healthcare sectors - Forbes India - December 3rd, 2022
- As N.W.T. mulls health coverage changes, petition calls for preventative HIV drug to be free - CBC.ca - September 20th, 2022
- EU regulator backs wider use of AstraZeneca COVID therapy - Reuters - September 20th, 2022
- Choose integrative medicine for health and wellness - Technique - September 20th, 2022
- The high hospital bills we make victims of rape and sexual violence pay - Vox.com - September 20th, 2022
- 4 Anti-Aging Products Youre Using All Wrong, According To Skincare Experts - SheFinds - September 20th, 2022
- Why Now is the Time to Double Down on Virtual Care - HIT Consultant - September 20th, 2022
- Tell Giselle: The price of good help is priceless - Wilkes Barre Times-Leader - September 20th, 2022
- Heron Therapeutics Announces U.S. FDA Approval of APONVIE (HTX-019) for the Prevention of Postoperative Nausea and Vomiting (PONV) - BioSpace - September 20th, 2022
- Pickleball injuries are on the rise: 5 preventive tips to keep you on the court - The Manual - September 20th, 2022
- The next big social movement and other takeaways from our regular meeting - POLITICO - September 20th, 2022
- 15 Mushrooms and How to Use Them in Vegan Cooking - VegNews - September 20th, 2022
- Use of honey in the management of Chemotherapy | CMAR - Dove Medical Press - September 20th, 2022
- Celebrity Strategy Consultant Predicts What Will Be The Most Impactful Area In The Pharmaceutical Industry - Forbes - September 20th, 2022
- C2C Care Course The Preservation of Our Global Photographic Heritage: Here, There and Everywhere - aam-us.org - August 3rd, 2022
- Loneliness: Causes, Effects And Prevention Forbes Health - Forbes - August 3rd, 2022
- Prevention and wellness is the new model, a leader from Henry Ford Health System says - Becker's Hospital Review - August 3rd, 2022
- FACT SHEET: White House Summit on Building Lasting Eviction Prevention Reform - The White House - August 3rd, 2022
- Getting Back to Employer Health and Wellness Programs - Cone Health - August 3rd, 2022
- Do ICDs Still Work in Primary Prevention Given Today's HF Meds? - Medscape - August 3rd, 2022
- Alzheimer's-defying brain offers clues to treatment, prevention - Harvard Gazette - August 3rd, 2022
- Wind-fanned lightning fire prompted precautionary evacuation notices near Medical Springs Sunday evening - Baker City Herald - August 3rd, 2022
- Experts discuss importance of cancer screenings and early detection - Merck - August 3rd, 2022
- King Institute of Preventive Medicine and Research to test samples for monkeypox - The Hindu - August 3rd, 2022
- Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations - World - ReliefWeb - August 3rd, 2022
- Dr. Sanjay Gupta: While monkeypox cases rise, why are we waiting for the cavalry to rescue us? - CNN - August 3rd, 2022
- SCYNEXIS Announces U.S. Food and Drug Administration - GlobeNewswire - August 3rd, 2022
- Governor Whitmer declares August 2022 as Breastfeeding Month, highlights additional breastfeeding observances - Michigan (.gov) - August 3rd, 2022
- New student education program supports drug and alcohol abuse prevention - The Ohio State University News - July 25th, 2022
- Suicide prevention training for health care providers a first step in longer-term efficacy - University of Washington - July 25th, 2022
- Pharmalittle: Congress may miss deadline to pass FDA user-fee bill; ViiV is urged to lower price for its HIV prevention drug - STAT - July 25th, 2022
- Prevention of Bipolar Disorder Episodes: Is It Possible? - PsychCentral.com - July 25th, 2022
- GAO Found Gap in Dirty Bomb Prevention - Government Technology - July 25th, 2022
- Florida man in apparent medical distress crashes car through beach crowd before hitting the water - CNN - July 25th, 2022
- Study: Preventive care scarce in LGBTQ+ community - - Medical Marketing and Media - July 25th, 2022
- The rise of preventive insurance purchases in India - ETHealthWorld - July 25th, 2022
- Why Are My Feet Always Cold? Cold Feet Causes and Treatment - Prevention Magazine - July 25th, 2022
- Agency looking to open overdose prevention site in Saint John amid 'poisoned' drug supply - CBC.ca - July 25th, 2022
- UVA Expert Offers Insight on the Use of Dietary Supplements for Cancer Prevention - UVA Today - July 25th, 2022
- Alzheimer's: Targeting key protein in blood may slow progression - Medical News Today - July 25th, 2022
- NPPC, FAS focused on ASF prevention in the Philippines - MEAT+POULTRY - July 25th, 2022
- Implementation of IPT in people living with HIV | RMHP - Dove Medical Press - July 25th, 2022
- NL starts preventive vaccination against monkeypox in Amsterdam, The Hague - NL Times - July 25th, 2022
- Precautionary measures you can take against brain haemorrhage - Times of India - July 25th, 2022
- Acid Reflux and Liver Disease: Signs, Symptoms and Prevention - Healthline - July 25th, 2022
- What to do if you get an allergic reaction: symptoms, causes, and prevention - Fox News - July 25th, 2022
- How one woman took control of her rare disease and achieved her dream - Times of Oman - July 25th, 2022
- Tilman Fertitta donating $50 million to UH medical school, which will be renamed after him - Houston Chronicle - May 20th, 2022
- This new 3D screensaver collection includes a driving tour of global pylons - Rock Paper Shotgun - May 20th, 2022
- Dedication, generosity and compassion that had no limit! - The Sun Chronicle - May 20th, 2022
- Manhattan internist and cardiologist, Dr. William Priester collaborates with Castle Connolly Private Health Partners to create a new concierge medical... - May 20th, 2022
- Tips on avoiding mosquitos this summer - morethanthecurve.com - May 20th, 2022
- Nanomedicine and HIV Therapeutics - AZoNano - May 20th, 2022
- The HIV Vaccine: What We Know, And What We Don't - MadameNoire - May 20th, 2022
- What we know (and don't know) about North Korea's COVID-19 outbreak - WCVB Boston - May 20th, 2022
- Experts warn of health effects from dusty conditions as sandstorm blankets UAE - Al Arabiya English - May 20th, 2022
- Statin therapy: Does the gut microbiome affect outcomes? - Medical News Today - May 20th, 2022
- New Preventative Medicine Facility Wraps Work in NYC - Healthcare Construction and Operations News - November 7th, 2021
- MPD working with faith-based leaders to fight violent crime - FOX13 Memphis - November 7th, 2021
- Cornell grad and lecturer touts benefits of plant-based diet - ithaca.com - November 7th, 2021
- Meet the Cork-born bread activist who has Goldie Hawn buying her loaves - Irish Examiner - November 7th, 2021
- Pfizer says pill cuts risk of severe Covid by 89% - RTE.ie - November 7th, 2021
- The roots of ivermectin mania: How South America incubated a fake-medicine craze that took the US by storm - Yahoo News - November 7th, 2021