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Is there any help for chemotherapy-induced neuropathy? – STLtoday.com

August 16th, 2020 12:59 am

I have often tried gabapentin (Neurontin) or a similar drug, pregabalin (Lyrica), but have not had much success. Duloxetine (Cymbalta) has evidence showing effectiveness at reducing pain and improving numbness, and those treated with duloxetine had a better quality of life than those on placebo. Finally, a preliminary trial showed a compounded cream containing baclofen, amitriptyline and ketamine showed some benefit.

Dear Dr. Roach An ear, nose and throat specialist told me not to use nasal sprays that contain oxymetazoline, such as Afrin, since over time they will damage and erode the tissues of the septum and inner nose. He said to use simple salt solution instead. Is this true? I used two shots of this nasal spray, and it cleared my sinuses and nose but was very uncomfortable. I have to be careful since I have had a constructive rhinoplasty and a septoplasty with reduced tissues. S.L.

Answer I agree wholeheartedly with your ENT doctor that long-term use of oxymetazoline nasal sprays, such as Afrin, can cause problems with the lining of your nasal passages. However, there are some times when Afrin or similar sprays are helpful. I have recommended it for people with colds or sinus infections before going on a plane, for example, since it is very effective in short-term use (no more than three days).

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Is there any help for chemotherapy-induced neuropathy? - STLtoday.com

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