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Archive for April, 2020

Cooking in the age of coronavirus: Boost your immune system with fresh juices – Commercial Appeal

Tuesday, April 7th, 2020

Fresh fruit and vegetables juices are a great way to boost your immunity(Photo: Getty Images/iStockphoto)

Fresh juices are a great way to boost your immunesystem.

According to Scott Tashie, owner of City Silo Table + Pantry and I Love Juice Bars in Memphis, the best juices to build immunity are orange, carrot and apple.

The antioxidants in apples help to protect your cells from the free radicals floating around, while carrots provide beta-carotene, another great antioxidant. Oranges are an excellent source of Vitamin C, something very vital when fighting off an illness.

During times like this, Tashie focuses on keeping his Vitamin C in check as well as getting the appropriate greens into his diet. Add in some pineapple with kale, spinach, parsley, celery, mint, lemon and ginger and you are good to go, he said.

Tashie offered these tips for juicing at home:

Dont be afraid to experiment.Sometimes the best juices happen when you arent trying at all, and they come out fantastic.

Not all fruits will juice the same flavors every time. Be prepared to tweak your recipe from time to time.

Juice more than one juice at a time. That way you can have enough for the whole day and maybe the following day. Be careful to store properly because it is not pasteurized.

Dont get discourage by the cleanup. Its part of it.

Jennifer Chandler is theFood & Dining reporter at The Commercial Appeal. She can be reached atjennifer.chandler@commercialappeal.com, and you can follow her on Twitter and Instagram at @cookwjennifer.

For the next few weeks, The Commercial Appeal Food & Dining reporter Jennifer Chandler will post shopping and recipe tips to help you put a delicious and healthy meal on the table. Chandler is the author of four cookbooks, including "The Southern Pantry Cookbook."

Read or Share this story: https://www.commercialappeal.com/story/entertainment/dining/2020/04/07/coronavirus-cooking-fresh-juices-city-silo-i-love-juice-bar/5114858002/

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Foods that boost the immune system – Asheboro Courier Tribune

Tuesday, April 7th, 2020

ASHEBORO During the current COVID-19 pandemic, health authorities have stressed that one group of people most vulnerable are those with compromised immune systems. With that in mind, are there ways we can boost our immunity to disease?

We asked Jeannie Leonard, Family and Consumer Science agent at Randolph County Cooperative Extenstion, and Jodi Meier, a registered dietitian and nutritionist in Randolph County Public Healths WIC office, for lists of foods that boost the immune system. They responded with a wealth of information.

Leonard provided a list of foods and details showing how they work. She even added three healthy recipes, all of which sound tasty.

IMMUNE-BOOSTING FOODS

Citrus Fruits Most people turn to vitamin C after theyve caught a cold. Thats because it helps build up your immune system. Vitamin C is thought to increase the production of white blood cells.

Red Bell Peppers Ounce for ounce, red bell peppers contain twice as much vitamin C as citrus fruits.

Ginger Ginger may help decrease inflammation, which will aid in reducing a sore throat and other inflammatory diseases.

Garlic Garlic may help lower blood sugar and slow down the hardening of your arteries. It was used as a home remedy for fighting infections in early civilizations.

Broccoli Broccoli is supercharged with vitamins and minerals, packed with vitamins A, C and E, and loads of antioxidants. Broccoli has the most effect when it is less cooked.

Spinach Like many of the other superfoods, spinach is packed with vitamin C, but also with numerous antioxidants and beta-carotene, which may increase the infection-fighting ability of our immune systems. Like broccoli, spinach has the most effect when it is less cooked.

Turmeric Turmeric is best known for use in curries, but has been used for years as an anti-inflammatory for treating arthritis.

Almonds Loaded with vitamin E, nuts such as almonds are packed also with healthy fats. A half-cup serving of almonds provides almost 100 percent of the recommended daily amount of vitamin E.

Yogurt Look for yogurts that have "live and active cultures" printed on the label, like Greek yogurt. These cultures may stimulate your immune system to help fight diseases.

Green Tea Both green tea and black tea are packed with flavonoids, a type of antioxidant.

Poultry Poultry, such as chicken and turkey, is high in vitamin B-6. About 3 ounces of light turkey or chicken meat contains 40-50 percent of your daily-recommended amount of B-6.

Sunflower Seeds Sunflower seeds are full of nutrients, including phosphorous, magnesium and vitamin B-6, and super filled with vitamin E.

Papaya Papaya is another fruit loaded with vitamin C. You can find 224 percent of the daily-recommended amount of vitamin C in a single papaya. Papayas also have a digestive enzyme called papain that has anti-inflammatory effects.

Kiwi Like papayas, kiwis are naturally full of a ton of essential nutrients, including folate, potassium, vitamin K, and vitamin C. Vitamin C boosts white blood cells to fight infection, while kiwis other nutrients keep the rest of your body functioning properly.

Shellfish Shellfish such as clams, crab, lobster and mussels are loaded with zinc, which our bodies need, so that our immune cells can function as intended.

TRY THESE RECIPES

Leonard, known for her cooking at Cooperative Extension, added a bonus with these three recipes:

SUPER IMMUNE-BOOSTING SOUP

Ingredients

1 tablespoon olive oil

1 large yellow onion, chopped

6 garlic cloves, minced

2 celery stalks, sliced

1 lb. fresh mushrooms, sliced

1 1/2 teaspoon sea salt

1/4 teaspoon black pepper

1 teaspoon turmeric

12 cups water

4 heads baby bok choy, bottoms chopped off

1/2 head kale, chopped

1 tablespoon freshly grated ginger

Directions

Heat olive oil in a large pot over medium heat. Add onions and saut for 5 minutes or until translucent. Add in garlic and cook for 1 more minute. Add in celery and mushrooms and saut for about 10 minutes or until mushrooms have wilted. Add in spices (including ginger, if using) and water and bring to a boil. Then let simmer, covered for 1 hour or in a crock-pot for 3-4 hours on low. Add bok choy and kale in the last 10 minutes of cooking to wilt. Serve warm or store for up to 1 week in the refrigerator. Yields 6-8 bowls.

GREEN COLD FIGHTING SMOOTHIE

Ingredients

2 ripe bananas

1 ripe apple, chopped

2 cups kale leaves, stems removed

1/2 cup orange juice, cold or frozen, no sugar added

1/2 cup cold water

12 ice cubes

1 tablespoon ground flaxseed or flax meal

1/2 tablespoon ground turmeric

Directions

Place bananas, apple, kale, orange juice, water, ice cubes, flaxseed and turmeric in a blender.

Pulse a few times, then puree until smooth, scraping down the sides as necessary.

THYME ROASTED ALMONDS

Ingredients

1 pound roasted, salted almonds

2 teaspoons good olive oil

2 tablespoon minced fresh thyme leaves

1 teaspoon kosher salt

1 teaspoon sea salt

Directions

Preheat the oven to 350F. Place the almonds, olive oil, thyme, and kosher salt on a sheet pan and toss together. Roast the almonds for 10-15 minutes, turning them every 5 minutes with a metal spatula, until they are lightly browned. Watch them carefully, they burn very easily.

Sprinkle with sea salt, toss and set aside to cool, serve at room temperature.

KEEP YOUR SYSTEM HEALTHY

Meier referred to an article from the Academy of Nutrition and Dietetics Eat Right, titled How to Keep Your Immune System Healthy.

The following nutrients play a role in the immune system and can be found in a variety of foods:

Beta Carotene is found in plant foods such as sweet potatoes, spinach, carrots, mango, broccoli and tomatoes.

Vitamin C-rich foods include citrus fruits, berries, melons, tomatoes, bell peppers and broccoli.

Vitamin D is found in fatty fish and eggs. Milk and 100 percent juices that are fortified with vitamin D also are sources of this important nutrient.

Zinc tends to be better absorbed from animal sources such as beef and seafood, but also is in vegetarian sources such as wheat germ, beans, nuts and tofu.

Probiotics are "good" bacteria that promote health. They can be found in cultured dairy products such as yogurt and in fermented foods such as kimchi.

Protein comes from both animal and plant-based sources, such as milk, yogurt, eggs, beef, chicken, seafood, nuts, seeds, beans and lentils.

FOCUS ON BALANCE

To help keep your immune system healthy all year long, focus on a balanced eating plan, adequate sleep and stress management.

Eat well Aim for five to seven servings of vegetables and fruits daily to get vitamins, minerals and antioxidants that may support immune health.

Defeat germs Good hygiene and hand-washing help prevent the spread of germs. Remember to wash produce before eating or using in recipes. Clean glasses, forks, spoons and other utensils to reduce the spread and growth of bacteria.

Relieve stress Find healthy and appropriate ways to cope with stress, such as meditation, listening to music or writing. Physical activity also is a great way to help manage stress and may help reduce the risk of some chronic diseases that could weaken your immune system further.

Get some sleep Lack of sleep contributes to a variety of health concerns, such as a weakened immune system. Seven to nine hours is recommended each day for adults, and children need eight to 14 hours, depending on their age.

WHAT ABOUT HERBALS?

Many herbal remedies are marketed to help fight colds or shorten their duration, but check with your health care provider before taking any supplements or medications. No one food or supplement can prevent illness.

OTHER ADVICE

Meier also provided an article by Food & Nutritions Lori Zanini titled 6 Ways to (Naturally) Boost Your Immune System in which she suggests these strategies:

Get friendly with garlic When I saw a study that showed when healthy people took a garlic supplement for three months in cold and flu season, their immune cells became more active than those who took a placebo, I was in! Reap the benefits by taking a high-quality garlic supplement or, if you dont mind the garlic breath, use raw, crushed garlic in everything from salad dressings to homemade hummus which showed similar results to garlic pills in another study.

Go with your gut More and more studies are exploring the link between our immune system and our gut. The bacteria, or microbiota, that live and thrive in our gut play a major role in the strength of our immune system. To keep the healthy flora in tip-top shape, get probiotics from fermented foods such as kimchi, miso, yogurt and kombucha. Research indicates that probiotics improve the immune response and increase production of immune cells.

Focus on fiber Prebiotic fiber is the specific type of food that keeps the gut bacteria happy and healthy. When bacteria ferment this fiber in our gut, short chain fatty acids are released. Studies show that these short chain fatty acids play a role as immuno-modulators and increase the production of T-regulatory cells, which help to regulate other immune cells and the immune response. Translation? Eating plenty of prebiotic fiber from artichokes, onion, garlic, asparagus, bananas and jicama helps give your immune system that extra boost it needs during the cold and flu season.

Ditch the spoonful of sugar Evidence suggests that simple sugars in foods such as cookies, sweetened beverages and many highly processed foods can negatively impact white blood cells defense mechanisms to guard the body from foreign invaders. Yet another reason to reduce sugar intake and opt for whole fruit to satisfy your sweet tooth most of the time.

Get some sun Or vitamin D, that is. Studies show that vitamin D is a major immune system regulator that plays a role in the expression and activation of several types of immune cells, meaning those with low vitamin D levels are more likely to get sick. Be sure to get at least 15 minutes of daily SPF-free sun exposure and consume vitamin D-rich food sources such as cod liver oil and oily fish like salmon and herring. Or consider taking a vitamin D supplement.

Spice it up Spices and roots such as turmeric, clove, coriander and ginger have been shown to act as anti-inflammatory agents, improve immune system response, increase antibodies and act as antibacterial agents in the body. Spices couldnt be easier to incorporate into your diet use them whenever you are cooking to add a boost of flavor. You even can make your own immune-boosting spice mix so you always have it on hand.

Chances are not all these foods will trip your fancy, but most people will find something appetizing. Practicing these nutritional tips may not keep you from getting sick but, chances are, youll be better able to shake off illness. Plus, youll be healthier overall.

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Foods that boost the immune system - Asheboro Courier Tribune

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Stock up on these 9 healthy foods to boost your immune system during coronavirus, says doctor and dietitian – CNBC

Tuesday, April 7th, 2020

As cases of coronavirus continue to rise, taking daily precautions such as washing your hands, social distancing, exercising and getting enough sleep is key to lowering risk of infection.

But maintaining a healthy diet to help boost your immune system may also give you an edge. It's important to note that no research has been done on foods that help fight against COVID-19 specifically.

However, previous studies have found that eating certain foods can improve your health and strengthen your body's ability to fight other invasive viruses.

Here are nine expert-approved foods to stock up on during your next grocery store trip, along with creative ideas on how to add them to your diet:

Broccoli is also rich in vitamin C. Just half a cup contains 43% of your daily value of vitamin C, according to the NIH.

"Broccoli is packed with phytochemicals and antioxidants that support our immune system," says Sarin. It also contains vitamin E, an antioxidant that can help fight off bacteria and viruses.

According to the Dietary Guidelines for Americans, vitamin C is one nutrient Americans aren't getting enough of in their diet, so finding simple ways to add it in is crucial.

"To get the most out of this powerhouse vegetable, eat it raw or just slightly cooked," says Sarin. "I love sauteing broccoli with garlic and Parmesan, or stir-frying with bell peppers, ginger, garlic and mushrooms."

Chickpeas contain a lot of protein, an essential nutrient made of amino acids that help grow and repair the body's tissues. It's also involved in synthesizing and maintaining enzymes to keep our systems functioning properly,according to the Academy of Nutrition and Dietetics.

"Chickpeas are also packed with zinc, which helps the immune system control and regulate immune responses,"Emily Wunder, a dietitian and founder of the nutritious recipes siteHealthier Taste, tells CNBC Make It.

Roasted chickpeas are great as a quick great snack or salad topper. Make sure they're completely dry before roasting. Then add a few tablespoons of oil (vegetable, canola or grapeseed oil all work well) and bake at 400 degrees Fahrenheit, stirring halfway through until they're crispy.

For a nice kick, Wunder suggests adding some salt and paprika.If you're using canned chickpeas, she says you'll want to rinse them thoroughly to cut down on sodium content.

Wunder enjoys half a cup of strawberries to get 50% of her vitamin C needs for the day.

"Vitamin C is great for strengthening your immune system," she says, because it can help protect cells from damage caused by free radicals that we're often exposed to in the environment.

Wunder recommends adding chopped strawberries to yogurt, oatmeal or on top of whole wheat toast with peanut butter. "Of course, they go well with smoothies, too," she says.

"Not only is garlic full of flavor, but it's packed with health benefits such as lowering blood pressure and reducing risk of heart disease," according to Sarin. "Garlic's immunity-boosting abilities come from its heavy concentration of sulfur-containing compounds, which can help fight off some infections."

Garlic has been shown in the past to help ward off the common cold. In a 2001 study published in Advances in Therapy, participants who took garlic supplements were less likely to catch a cold. And those who did get infected recovered faster than participants in the placebo group.

It's an easy vegetable to work into your diet, says Sarin. You can add to it anything from pasta sauce and salad dressings to soups and stir-fry dishes. She suggests aiming to consume two to three cloves per day.

"While sun exposure is the best source of vitamin D, it can also be provided by some foods, including mushrooms," says Wunder.

A 2018 review of mushrooms as a vitamin D source found that the "sunshine vitamin" can help enhance the absorption of calcium, which is good for bone health, and may also protect against some cancers and respiratory diseases.

Mushrooms are great as a side dish or appetizer. Wunder recommends roasting them at about 350 degrees Fahrenheit, using one to two tablespoons of oil, minced garlic and a dash of salt and pepper. For something more flavorful, bake button mushrooms stuffed with cheese, onion andartichokehearts.

"Spinach is rich in vitamin C and full of antioxidants that help shield our immune cells from environmental damage," says Sarin. "Plus, it has beta carotene, which is the main dietary source of vitamin A an essential component of proper immune function."

Like broccoli, it's best to consume spinach raw or slightly cooked. To incorporate more spinach into your diet, Sarin suggests blending it in a smoothie, cooking it with your morning eggs or, as an easy side dish, lightly sauteing with garlic.

"Yogurt is a great source of probiotics, which are good bacteria that can help promote a healthy gut and immune system," says Sarin.Recent studies have also found probiotics to be effective for fighting the common cold and influenza-like respiratory infections.

Sarin recommends choosing plain yogurt rather than anything too flavored or sweetened and topping it with fruit and honey. "Or, you can add it to your favorite post-workout smoothie," she says.

Those on a dairy-free diet can still benefit from almond-milk and coconut-milk yogurt options.

"Sunflower seeds are high in vitamin E, which works as an antioxidant and helps boosts the immune system," says Wunder.

Small but mighty, just one ounce of dry-roasted sunflower seeds can give you 49% of your daily value of vitamin E, according to the NIH.

Line a baking pan with parchment paper and roast unshelled sunflower seeds at 300 degrees Fahrenheit until they're lightly browned. Then add the seeds to your salad or toss them with roasted vegetables. You can also use raw seeds in place of pine nuts for some homemade pesto.

Brittany Anas is a health and nutrition reporter. She has written forHealthDay, Women's Health and The Denver Post. Follow her on Twitter @BrittanyAnas.

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Doctor weighs in on toll of stress on immune systems during COVID-19 pandemic – KXAN.com

Tuesday, April 7th, 2020

AUSTIN (KXAN) An Austin doctor said the toll of stress can have a significant impact on the immune system, which could be especially heightened during the COVID-19 pandemic.

KXAN spoke with one doctor who gave her insight on how people can manage that stress with her own approach.

The toll of the stress is tremendous and actually again affects our immune systems ability to fight off infections in general, said Dr. Ann Shippy, an Austin-based chemical engineer turned doctor. One of the things we can all be doing is managing our mindset that we do the things like exercise, meditate, get good sleep and focus on the things we can control.

Dr. Shippy describes her strategy to treatment as functional medicine, using science, testing and genetic information to try and treat the root cause of symptoms, instead of just managing them.

Dr. Shippy said another way to manage stress is to offer a helping hand to the community.

That could include making masks, amid the personal protective equipment shortage for healthcare workers, or providing food for those in need.

KXAN Simple Health is launching an initiative which focuses on maintaining mental wellness during the COVID-19 pandemic. Well highlight topics including parenting, finances and jobs, grief and anxiety, senior health and balancing isolation and socializing from a distance.

Look for our special coverage starting Sunday, April 5.

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Commentary: I’ll trust my immune system over the media – Lewiston Morning Tribune

Tuesday, April 7th, 2020

This is not a news report. It is my opinion column, on the Opinion page of your community newspaper. Nevertheless, I dont write about things I havent researched.

Apply whatever value to that you wish.

Can we please tone down the hysteria and put this in perspective? Lets examine what COVID-19 is not.

COVID-19 is not a reason to buy outrageous amounts of toilet paper.

COVID-19 is not the 1918 H1N1 (Spanish) flu pandemic, before flu vaccine development. Estimates are 500 million were infected and about 50 million died as the disease raced around the world at the speed of trains and steamboats. In the U.S., 675,000 people died.

COVID-19 is not the 2009 version of the H1N1 (swine) flu pandemic, which infected nearly 61 million Americans, and killed 12,469.

COVID-19 is not the 1921 diphtheria epidemic, with 206,000 cases and 15,520 deaths across all age groups of the 106 million people then living in the U.S. That was a nearly 8 percent death rate of those infected.

COVID-19 is not even remotely like those three events, with only about a 1.4 percent death rate nationally.

Today, diseases (and information) travel by jet and internet. The world knew instantly that Tom Hanks and his wife, Rita Wilson, on location in Australia, tested positive for COVID-19. They recovered without hospitalization.

COVID-19 is not this years influenza. Americans are apparently not afraid of the flu any more because about 43 percent of them fear the shot and dont get vaccinated. Nor do they rush out annually to stockpile toilet paper and hand sanitizer.

Perspective: Imagine that when the flu season happens each year, news media would breathlessly report (with bold capital headlines) every new case, every day. The news would seem truly catastrophic, reflecting the 38 million U.S influenza cases this season, with 400,000 hospitalized. The flu has killed 24,000 Americans. A half-million may die worldwide in a typical season.

Perspective: Suggested Lewiston Tribune poll question If you are one of those who avoid the flu vaccine, will you get the COVID-19 vaccine when one is developed?

COVID-19 is not a reason for the news media to flash the number of coronavirus cases and deaths on TV in real time, goosing your panic every four seconds to believe were literally going up in smoke.

The Lewiston-Clarkston Valley is not New York City. And no matter how badly Washington Gov. Jay Inslee wants to be the center of attention, one nursing home in Kirkland does not represent Washington. If not for that one facility, Washington statistics would not stand out.

As this is written, New York City, with about 2.5 percent of the nations population, has about 42 percent of the national coronavirus associated deaths. New York City has about 27,000 people per square mile. Imagine Lewiston with 522,912 people. Thats New York City. If one person sneezes, 13 people reach for a hanky.

New York City is a laboratory for COVID-19. It wont be surprising if most in that teeming ball of earthworms get the disease as if I needed any more reasons to not visit.

COVID-19 does not kill directly. Death comes from respiratory complications, i.e., pneumonia. This mutated cousin of the common cold virus wasnt around when immune systems were young and vital, and immune systems weaken with age. This may be why most young folks are not showing symptoms. Most of them could suffer a slight cough and wont notice a mild fever. Their most serious problem will be a restricted social life.

This is all logical and provable by cases to date. Nationally, nearly 99 percent with COVID-19 symptoms recover without hospitalization. Most deaths were older and/or already at risk, with compromised respiratory or immune systems.

Perspective about statistics: In any reasonable statistical analysis, New York City, despite the national news exposure its getting, would be thrown out of the national calculation as what is known as an outlier. The same is true of the Kirkland nursing home for Washingtons statistics. The presumption that every major city (or the nation) will follow New York Citys (or Italys) pattern in a few weeks is just hysterical statistical nonsense.

Perspective: Comparing American statistics to China, Italy or Iran is likewise wrong. With among the worlds highest populations of at-risk seniors and relatively high numbers of smokers, those countries are naturally more susceptible. In addition, thousands of Wuhan Chinese workers traveled to Italy and Iran for a massive infrastructure construction program. New York Citys first case reportedly came from an Iranian immigrant.

Perspective: Normally, of Chinas 1.4 billion people, about 28,000 people die every day. The Chinese coronavirus death toll is about three hours of an average Thursday. The Chinese deserve credit for even noticing this outbreak with only a few thousand extra deaths, mostly health-compromised elderly.

COVID-19 is not the 2003 SARS epidemic (another Chinese coronavirus), which infected 8,098 people worldwide and killed 774, nearly 10 percent of patients, compared, again, to COVID-19s roughly 1.4 percent.

Perspective: In America normally, between 3,000 and 7,000 people die every day from something. About 700 of those are Californians. Yet Californias COVID-19 death rate is about one person for every 250,000 citizens.

Gov. Inslee adds to the panic by reacting as if every positive COVID-19 tests results in intensive-care hospitalization. That is not what is happening. What is happening is that increased testing results in more positives, not a more serious disease. Over-reacting stupidly does not solve a problem.

America was poorly prepared for a truly lethal pandemic. Our outsize reaction may be good practice for if and when a truly lethal disease erupts, but the real danger now is the increased hysteria destroying the economy.

Im 72, a child of the Greatest Generation and a former soldier myself. Id rather catch this damned disease and trust my immune system to beat it than watch the media and political idiots distort events, trying to damage this president.

Whether you like the man or not, the president is demonstrating uncommon and laudable leadership; America is fortunate to have him.

Rogers of Clarkston is a retired manager at CCI-Speer (now Vista Outdoor). His email address is rrogerr76@gmail.com.

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Cocoa and the coronavirus: can it boost the immune system? – ConfectioneryNews.com

Tuesday, April 7th, 2020

Lemon juice, mosquito bites and blood donations? There are plenty of coronavirus health myths circulating online, which ConfectioneryNews doesnt wish to perpetuate in any shape or form, but there is case for cocoa right now to help boost the human bodys immune system.

Lets be clear: cocoa is not a cure for coronavirus, The Covid-19 outbreak is a new illness and scientists are still assessing how it spreads from person to person, but similar viruses tend to spread via cough and sneeze droplets. Only a vaccine can prevent people from getting sick and the World Health Organization says approximately 35 companies and academic institutions are racing to create such a vaccine.

However, in a 2015 medical study*, it was revealed that cocoa contains biologically active ingredients that have broad-spectrum antimicrobial activity, which includes an inhibitory effect on influenza virus infection.

The reports conclusion: Drinking cocoa activates natural immunity and enhances vaccination-induced immune response, providing stronger protection against influenza virus infection and disease onset.

Dr Edward Ampofo of Ghanas Cocoa Clinic has also claimed that cocoa does not only help to boost the immune system but equally helps to protect the human body against infection.

In a video posted on ghanaweb.com, he explained that the immune functions of cocoa are mainly related to what he called its polyphenol content and methylxanthine-theobromine.

The immune system protects the body against germs and foreign materials," he explained, saying it is made up of two components - innate and adaptive. The innate immune response is inborn or natural.

He told ghanaweb.com oxidative stress has been identified as a major factor in inhibiting the immune system from performing its normal functions.

Oxidative stress is essentially an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants.

There is oxidative stress in infections and the body usually mobilizes, for example white blood cells in such situations. Polyphenol-rich cocoa is a strong antioxidant and therefore able to mop up these free radicals produced via oxidative stress and in turn normalizes the functions of the immune system.

He said cocoa is recognized as the highest source of polyphenols of all foods on weight basis and polyphenol-rich cocoa, apart from its antioxidant properties is able to independently act on the immune system to perform its functions to the desired level.

* Study:Anti-influenza virus effects of cocoa.Kamei M1, Nishimura H2, Takahashi T1, Takahashi N1, Inokuchi K3, Mato T3, Takahashi K2.

News source: Consume more cocoa to fight coronavirus Ghanaians told

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Support Immune Function and Muscle Health With Rejuvenate During Prolonged Inactivity – GlobeNewswire

Tuesday, April 7th, 2020

Rejuvenate Helps Prevent Muscle Loss

Rejuvenate is an affordable nutritional supplement and the first of its kind to generate positive muscle response without exercise. However, when used with exercise, Rejuvenate doubles its ability to rebuild and repair muscle.

Rejuvenate Supports Optimal Immune System Function

Rejuvenate consists of the essential amino acids that are critical to immune function including leucine, valine and isoleucine and comes in individual powder pouches and can be easily mixed with water.

BURLINGTON, Ontario, April 07, 2020 (GLOBE NEWSWIRE) -- While people are stockpiling common immune-strengthening supplements like vitamins C, D and zinc, one group of overlooked nutrients that are critical during a prolonged period of inactivity is essential amino acids that play a major role in protein synthesis and the formation of white blood cell and antibodies. With limited exercise options during lockdowns, quarantines and social distancing, muscle loss can play a bigger role than most realize it can increase your susceptibility to sickness. A proprietary muscle health and repair supplement called Rejuvenate, by Element Nutrition, has 25 clinical peer reviewed published studies to demonstrate its efficacy including increasing the bodys ability to rebuild and repair muscle by 57% with noticeable muscle mass improvement within just 30 days. In one study published by The Journal of Clinical Endocrinology & Metabolism, patients on bed rest gained muscle mass with Rejuvenate compared to those who experienced muscle loss who were not taking the supplement.

Amino acids are not simply building blocks of protein, they are important building blocks of antibodies, which are produced by the bodys immune system to help fight off foreign invaders, like bacteria and viruses. If your body lacks adequate essential amino acids, it can lead to a compromised immune system. According to The Journal of Nutrition, the immune system has a high dependence upon protein synthesis, since mounting an immune response requires generation of new cells and synthesis of antigen-presenting machinery (immunoglobulins, cytokines, cytokine receptors, acute phase proteins). Without these essential amino acids, as found in Rejuvenate, synthesis of these proteins do not occur optimally and therefore can result in a compromised immune system.

Protein provides energy for the body. It is a macronutrient and if you dont have enough protein or become deficient in essential amino acids you can start to experience weakness and fatigue, even lack of focus and brain fog and sometimes depression, said Dr. Christine Horner, a leading authority on integrative and preventative health who has consulted with hundreds of patients facing life-threatening cancerdiagnoses on how to strengthen the immune system when the body is under constant attack. Protein is also a component of hemoglobin, which is present in red blood cells and responsible for transporting oxygen throughout the body. When oxygen levels drop it can cause weakness or even shortness of breath.

According to the British Journal of Nutrition, a deficiency of dietary protein or amino acids impairs immune function and increases the risk of infectious disease. Protein malnutrition reduces concentrations of most amino acids in plasma. Findings from recent studies indicate an important role for amino acids in immune responses by regulating the activation of T lymphocytes, B lymphocytes, natural killer cells and macrophages; cellular redox state, gene expression and lymphocyte proliferation; and the production of antibodies, cytokines and other cytotoxic substances. Increasing evidence shows that dietary supplementation of specific amino acids in animals and humans with malnutrition and infectious disease enhances the immune status, thereby reducing morbidity and mortality.These are the same amino acids found in Rejuvenate.

If you become protein deficient for too long, the body will borrow protein from other areas including the storage in our skeletal muscle tissue in order to transfer it to more essential organs and the brain. Once this happens your bones will become more at risk to injuries like fractures and breaks, said Horner, who notes that in one clinical study published by the Journal of Aging Research & Clinical Practice, Rejuvenate increased the strength of knee and hip replacement patients, post-surgery, by 800%. Our bodies are not designed to store protein for long-term, future use so we need to consume enough protein every day to ensure the body gets what it needs to work efficiently. Plus, when it comes to protein and your immune system, it turns out that even marginally low protein intake may impair its function.

Rejuvenate is an affordable nutritional supplement developed by one of the worlds leading researchers in protein and amino acid nutrition. Its the first supplement of its kind to generate positive muscle response without exercise. However, when used with exercise, Rejuvenate doubles its ability to rebuild and repair muscle. Age-related muscle loss may begin as early as age 40. After age of 60, muscle mass declines at an annual rate of 1.5-3% per year and 50% of adults age 80 and above have sarcopenia, a distinct medical condition recognized by The Centers for Disease Control and Prevention. Rejuvenate consists of the essential amino acids that are critical to immune function including leucine, valine and isoleucine, and comes in individual powder pouches and can be easily mixed with water. Horner says daily intake of Rejuvenate can help prevent muscle loss and support optimal immune system function. Rejuvenate is available at major retailers, Amazon and http://www.rejuvenatemuscle.com.

Photosaccompanying this announcement are available athttps://www.globenewswire.com/NewsRoom/AttachmentNg/d99b44ef-9815-4dc2-8ab4-3d19199a45bf

https://www.globenewswire.com/NewsRoom/AttachmentNg/17156ff8-22d4-4855-9ab6-29906b5848b8

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Vitamin D3 boosts the immune system, our first line of defence – The National

Tuesday, April 7th, 2020

WHILE the world is on hold as Covid-19 accelerates its global rampage, an exit strategy seems many months away. Herd immunity is a distant prospect, as are vaccines or drug treatments. However, there is a measure with the potential to help in this crisis at the cost of about 1p/day per capita, that would promote our defences, vitamin D3. This steroid hormone promotes the innate immune system, our first line of defence against microbes, including coronaviruses, but the UK population is commonly D3-deficient, often severely, as is also common globally. We suggest, therefore, based on the accompanying scientific and medical evidence, that efforts be made to improve vitamin D repletion to help reduce both morbidity and mortality from, and perhaps also susceptibility to, Covid-19.

Vitamin D (D3) is the sunshine vitamin. Our skin makes it under summer sun but most British people dont make enough because we live and work indoors, live at high latitude and eat little wild oily fish (the only good food source of this vitamin), while deficiency is also a global problem.

Scientific evidence from peer-reviewed publications shows that vitamin D is needed both for healthy bones and for a healthy immune system which can defend us against most bacteria and viruses at adequate blood levels of the vitamin D metabolite 25(OH)D by gene modulation, and that also reduces inappropriate inflammation.

What is an adequate blood level of 25(OH)D?

25 nmol/l was thought enough until 20 years ago, now we know it should be more than 50 nmol/l, a target used throughout the NHS. Higher levels are advised by many experts at 100 150 nmol/l, for optimal health (1), as are achieved by natives of the tropics.

We have a high degree of deficiency, worst in Scotland

One third to a half of all people are deficient across the UK, with severe deficiency increasingly common in the north.

Benefits of supplementation In addition to the prevention of rickets and osteomalacia, and reduction of the risks of increasing numbers of chronic disorders, both survival with cancer and the risk of getting certain cancers are reduced by better vitamin D status (2-6).

Respiratory infection rate reduction

Evidence from animal, cell and molecular research shows that lack of vitamin D increases the risks of many chronic diseases; supplementation of deficient people can reduce many such risks, including upper respiratory tract infections as shown in a summary of 25 studies where deficient subjects amongst 11,000 participants supplemented with vitamin D showed over 70% reduction in infection rates with certain common viruses. (7).

A recent review concludes: To reduce risk of infection, it is recommended that people at risk of influenza and/or Covid-19 consider taking 10,000 IU/d of vitamin D3 for a few weeks to rapidly raise 25(OH)D concentrations, followed by 5000 IU/d. The goal should be to raise 25(OH)D concentrations above 4060 ng/ml (100150 nmol/l). (8) Those authors called for randomised trials of vitamin D in Covid-19 patients.

Meanwhile, the evidence justifies ensuring that Covid-19 patients are not deficient, measuring serum 25(OH)D where possible, but more importantly, ensuring adequate supplemental intakes for all such patients. (9).

Barbara Boucher, honorary professor, LondonPeter Cobbold, emeritus professor, cell biology, LiverpoolDavid Grimes, retired consultant physician, ManchesterHelga Rhein, retired general practitioner, Edinburgh

References:

(1) https://www.grassrootshealth.net/wp-content/uploads/2017/12/scientists_call-to-daction_121817.pdf

(2) https://www.bmj.com/content/356/bmj.i6583

(3) https://www.bmj.com/content/356/bmj.i6583

(4) https://www.bmj.com/content/356/bmj.i6583

(5) https://www.bmj.com/content/356/bmj.i6583

(6) https://www.ncbi.nlm.nih.gov/pubmed/30654108

(7) https://www.bmj.com/content/356/bmj.i6583

(8) https://www.preprints.org/manuscript/202003.0235/v2

(9) https://docs.google.com/document/d/1jffdZOSuIA64L_Eur8qyCQ12T7NXrHSKPxtMe134C0Y/edit

Scotland is in lockdown. Shops are closing and newspaper sales are falling fast. Its no exaggeration to say that the future of The National is at stake. Please consider supporting us through this with a digital subscription from just 2 for 2 months by following this link:www.thenational.scot/subscribe. Thanks and stay safe.

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Early immune response in patients could be causing respiratory distress: Study – The Straits Times

Tuesday, April 7th, 2020

When a virus invades a body, the development of the disease is often determined by how the immune system reacts to the infection.

Most of the time, the immune system mounts a protective response. But sometimes, that response can be harmful too, experts say.

If the immune system kicks into overdrive, for instance, it could stimulate the overproduction of proteins called cytokines, which can cause inflammation.

Cytokines are molecular messengers of the immune system. For Covid-19 patients, this cytokine storm can lead to symptoms such as breathlessness or respiratory distress.

Now, a team of Singapore scientists have found that patients with Covid-19 could have a dynamic and fluctuating immune response to the virus, particularly in the early stages of the disease.

For instance, when the immune system responds in a way that causes the body to produce more cytokines, it correlates with the period when the patients become more sick and experience respiratory distress.

The study was published on March 28 in scientific journal Cell Host & Microbe.

The finding is important as it could pave the way for research into existing or new drugs that could help prevent harmful immune reactions that may worsen the disease, said Dr Eugenia Ong, a member of the team. She is senior research fellow at the Viral Research and Experimental Medicine Centre, a unit of the SingHealth Duke-NUS Academic Medical Centre, and at the Duke-NUS' Emerging Infectious Diseases programme.

In studying three Covid-19 patients in Singapore, the scientists found that the patients' immune systems showed marked changes in the way they dealt with the invading pathogen.

As molecular messengers, cytokines help to flag the presence of a foreign pathogen in the body, so other elements of the immune system can kick in to get rid of the virus.

But when the body produces too much of it, this can result in inflammation. This production of cytokines is regulated by genes, explained one of the study's lead authors, Associate Professor Jenny Low, a senior consultant at the Department of Infectious Diseases at Singapore General Hospital and co-director of the Viral Research and Experimental Medicine Centre.

The study noted that the processes that stimulate the production of cytokines in a patient differed from day to day.

The scientists found that one particular cytokine called Interleukin-1 was produced even before the patient showed clinical deterioration.

"In this study, we found that the early immune response following the start of symptoms is highly dynamic, which means that research needs to take into account the day-to-day fluctuations in activation or deactivation of immune genes that collectively shape disease severity in Covid-19 patients," said Prof Low, who is also an associate professor at the Emerging Infectious Diseases programme at Duke-NUS.

As the sensing of the foreign pathogen triggers a cascade of molecular events, characterising the immune response in the early phase of illness is thus important to understand how the final immune reaction is derived, said Prof Low.

Professor Lisa Ng, who was not involved in the research project, said the study of early stages of infection is interesting, as it may lead to opportunities for early interventions.

"Potentially, some clinically approved drugs could be used to target certain inflammatory pathways to control virus-induced inflammation," said Prof Ng, a senior principal investigator at the Agency for Science, Technology and Research's Singapore Immunology Network. However, she said it would be important to see if larger cohort groups from various countries will show similar patterns.

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Preventative medicine team works to beat COVID-19 – fortcarsonmountaineer.com

Tuesday, April 7th, 2020

COVID-19 can live on surfaces for hours or even days. In order to kill the virus and prevent people from becoming infected, you have to disinfect. 2nd Lt. Felicia Dreh

By Sgt. Liane Hatch

FORT CARSON, Colo. Considering the COVID-19 pandemic that has led to a statewide stay-at-home order, the 3rd Armored Brigade Combat Team, 4th Infantry Division, preventative medicine team encouraged Soldiers, leaders and Family members to practice thorough cleaning and disinfecting measures at home and in the workplace.

A lot of people think when you just spray the counter with a cleaner and wipe it up with a cloth or paper towel, that youre good to go, said 2nd Lt. Felicia Dreh, an environmental science officer, preventative medicine team, 3rd ABCT.

Dreh explained that many people have questions such as: If I clean something, do I need to disinfect it? Whats the difference? Are they the same? They are not.

Cleaning with just your normal spray cleaners just removes surface dirt, while disinfecting actually kills the bacteria, Dreh continued. COVID-19 can live on surfaces for hours or even days. In order to kill the virus and prevent people from becoming infected, you have to disinfect.

The Centers for Disease Control and Prevention (CDC) recommends a diluted bleach solution to properly disinfect high-traffic surfaces, such as countertops, doorknobs and handles.

Per CDC guidelines, you want to use five tablespoons or capfuls of bleach per gallon of water, or if youre using a spray bottle, you can use four teaspoons of bleach per quart of water, said Sgt. Wilbur Davis, NCO, preventative medicine team, 3rd ABCT. Use a clean sponge to wipe the area then and let that surface air dry.

Davis emphasized when using bleach solutions, its important to wear protective gloves, keep the area well-ventilated and avoid mixing with other cleaning products, especially those containing ammonia.

Both members of the preventative medicine team agreed that taking measures to clean and disinfect common areas should be part of a daily routine, both at work and in the Soldiers home.

You can spread COVID-19 from work to home or vice versa just by touching a doorknob after an infected person has touched it, Davis said. Soldiers should be disinfecting their spaces every day.

Dreh recommends taking the time to clean and disinfect a part of each units daily battle rhythm, preferably at the end of each day. While she acknowledged most leaders already have cleaning measures in place, they need to be sure Soldiers use bleach to disinfect those areas as well.

Commanders can help keep their Soldiers healthy by enforcing daily cleaning and disinfecting requirements, Dreh said. The more you do it, the less time it takes, and it will go a long way toward keeping everyone healthy.

In addition to using good disinfection measures, Soldiers and Family members can prevent the spread of disease and reduce the likelihood of illness by practicing good hand hygiene and avoiding touching their face, mouth, nose and eyes.

For more guidelines on COVID-19 prevention, visit https://www.cdc.gov/, and local procedures at https://www.carson.army.mil/ or follow @USArmyFortCarson on Facebook.

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Henry Ford Health System to conduct first large US study of hydroxychloroquines ability to prevent COVID-19 – TechCrunch

Tuesday, April 7th, 2020

Despite false assertions by the president to the contrary, any potential treatments to counter or prevent COVID-19 are still only at the stage of early investigations, which include one-off treatment with special individual case authorizations, and small-scale clinical examinations. Nothing so far has approached the level of scrutiny needed to actually say anything definitively about their actual ability to treat COVID-19 or the SARS-CoV-2 virus that causes it, but the first large-scale U.S. clinical study for one treatment candidate is seeking volunteers and looking to get underway.

The study will be conducted by the Henry Ford Health System, which is seeking 3,000 volunteers from healthcare and first responder working environments. Depending on response, the researchers behind the study are looking to begin as early as next week. Study lead researcher Dr. William W. ONeil said in a press release announcing the study that the goal is to seek a more definitive scientific answer to the question of whether or not hydroxychloroquine might work as a preventative medicine to help protect medical front-line workers with greater risk exposure from contracting the coronavirus.

Hydroxychloroquine (as well as chloroquine) has been in the spotlight as a potential COVID-19 treatment due mostly to repeated name-check that President Trump has given the drug during his daily White House coronavirus task force press briefings. Trump has gone too far in suggesting that the drug, which is commonly used both as an anti-malarial and in the treatment of rheumatoid arthritis and lupus, could be an effective treatment and should be thrust into use. At one point, he claimed that he FDA had granted an emergency approval for its use as a COVID-19 treatment, but Dr. Anthony Fauci clarified that it was not approved for that use, and that clinical studies still need to be performed to evaluate how it works in addressing COVID-19.

Studies thus far around hydroxychloroquine have been small-scale, as mentioned. One, conducted by researchers in France, produced results that indicated the drug was effective in treating those already infected, particularly when paired with a specific antibiotic. Another, more recent study from China, showed that there was no difference in terms of viral duration or symptoms when comparing treatment with hydroxychloroquine with treatment using standard anti-viral drugs, already a common practice in addressing cases of the disease.

This Henry Ford study looks like it could provide better answers to some of these questions around the drug, though the specific approach of seeking to validate prophylactic (preventative) use will mean treatment-oriented applications will still have to be studied separately. The design of the study will be a true blind study, with participants split into three groups that receive unidentified, specific pills (possibly anti-virals or some equivalent); hydroxychloroquine; or placebo pills, respectively. They wont know which theyve received, and theyll be contacted weekly by researchers running the study, then in-person both at week four and week eight to determine if they have any symptoms of COVID-19, or any side effects from the medication. Theyll get regular blood draws, and the results will be compared to see if theres any difference between each cohort in terms of how many contracted COVID-19.

These are front-line healthcare workers, so in theory they should unfortunately be at high risk of contracting the disease. That, plus the large sample size, should provide results that provide much clearer answers about hydroxychloroquines potential preventative effects. Even after the study is complete, other competing large-scale trials would ideally be run to prove out or cast doubt on these results, but well be in a better position than we are now to say anything scientifically valid about the drug and its use.

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Coronavirus symptoms: 10 key indicators and what to do – FOX Carolina

Tuesday, April 7th, 2020

Scientists are learning more each day about the mysterious novel coronavirus and the symptoms of Covid-19, the disease it causes.

Fever, cough and shortness of breath are found in the vast majority of all Covid-19 cases. But there are additional signals of the virus, some that are very much like cold or flu, and some that are more unusual.

Any or all symptoms can appear anywhere from two to 14 days after exposure to the virus, according to the US Centers for Disease Control and Prevention.

Here are 10 signs that you or a loved one may have Covid-19 -- and what to do to protect yourself and your family.

Shortness of breath is not usually an early symptom of Covid-19, but it is the most serious. It can occur on its own, without a cough. If your chest becomes tight or you begin to feel as if you cannot breathe deeply enough to fill your lungs with air, that's a sign to act quickly, experts say.

"If there's any shortness of breath immediately call your health care provider, a local urgent care or the emergency department," said American Medical Association president Dr. Patrice Harris.

"If the shortness of breath is severe enough, you should call 911," Harris added.

The CDC lists other emergency warning signs for Covid-19 as a "persistent pain or pressure in the chest," and "bluish lips or face," which can indicate a lack of oxygen.

Get medical attention immediately, the CDC says.

Fever is a key sign of Covid-19. Because some people can have a core body temperature lower or higher than the typical 98.6 degrees Fahrenheit (37 degrees Celsius), experts say not to fixate on a number.

CNN anchor Chris Cuomo, who is battling the virus from his home in New York, is one of those people.

"I run a little cool. My normal temperature is 97.6, not 98.6. So, even when I'm at 99 that would not be a big deal for most people. But, for me, I'm already warm," Cuomo told CNN Chief Medical Correspondent Dr. Sanjay Gupta in a CNN Town Hall.

Most children and adults, however, will not be considered feverish until their temperature reaches 100 degrees Fahrenheit (37.7 degrees Celsius).

"There are many misconceptions about fever," said Dr. John Williams, chief of the division of pediatric infectious diseases at the University of Pittsburgh Medical Center Children's Hospital of Pittsburgh.

"We all actually go up and down quite a bit during the day as much as half of a degree or a degree," Williams said, adding that for most people "99.0 degrees or 99.5 degrees Fahrenheit is not a fever."

Don't rely on a temperature taken in the morning, said infectious disease expert Dr. William Schaffner, a professor of preventative medicine and infectious disease at Vanderbilt University School of Medicine in Nashville. Instead, take your temperature in the late afternoon and early evening.

"Our temperature is not the same during the day. If you take it at eight o'clock in the morning, it may be normal," Schaffner explained.

"One of the most common presentations of fever is that your temperature goes up in the late afternoon and early evening. It's a common way that viruses produce fever."

Coughing is another common symptom, but it's not just any cough.

"It's not a tickle in your throat. You're not just clearing your throat. It's not just irritated," Schaffner explained.

The cough is bothersome, a dry cough that you feel deep in your chest.

"It's coming from your breastbone or sternum, and you can tell that your bronchial tubes are inflamed or irritated," Schaffner added.

A report put out by the World Health Organization in February found over 33% of 55,924 people with laboratory confirmed cases of Covid-19 had coughed up sputum, a thick mucus sometimes called phlegm, from their lungs.

"The beast comes out at night," said Cuomo, referencing the chills, body aches and high fever that visited him on April 1.

'It was like somebody was beating me like a pinata. And I was shivering so much that ... I chipped my tooth. They call them the rigors," he said from his basement, where he is quarantined from the rest of his family.

"I was hallucinating. My dad was talking to me. I was seeing people from college, people I haven't seen in forever, it was freaky," Cuomo said.

Not everyone will have such a severe reaction, experts say. Some may have no chills or body aches at all. Others may experience milder flu-like chills, fatigue and achy joints and muscles, which can make it difficult to know if it's flu or coronavirus that's to blame.

One possible sign that you might have Covid-19 is if your symptoms don't improve after a week or so but actually worsen.

Speaking of worsening signs, the CDC says a sudden confusion or an inability to wake up and be alert may be a serious sign that emergency care may be needed. If you or a loved one has those symptoms, especially with other critical signs like bluish lips, trouble breathing or chest pain, the CDC says to seek help immediately.

At first science didn't think diarrhea or other typical gastric issues that often come with the flu applied to the noval coronavirus, also known as SARS-CoV-2. As more research on survivors becomes available, that opinion has changed.

"In a study out of China where they looked at some of the earliest patients, some 200 patients, they found that digestive or stomach GI (gastrointestinal) symptoms were actually there in about half the patients," Gupta said on CNN's New Day news program.

Overall, "I think we're getting a little bit more insight into the types of symptoms that patients might have," Gupta said.

The study described a unique subset of milder cases in which the initial symptoms were digestive issues such as diarrhea, often without fever. Those patients experienced delays in testing and diagnosis than patients with respiratory issues, and they took longer to clear the virus from their systems.

Research from China, South Korea and other parts of the world indicate that about 1% to 3% of people with Covid-19 also had conjunctivitis, commonly known as pink eye.

Conjunctivitis, a highly contagious condition when caused by a virus, is an inflammation of the thin, transparent layer of tissue, called conjunctiva, that covers the white part of the eye and the inside of the eyelid.

But SARS-CoV-2 is just one of many viruses that can cause conjunctivitis, so it came as no real surprise to scientists that this newly discovered virus would do the same.

Still, a pink or red eye could be one more sign that you should call your doctor if you also have other telltale symptoms of Covid-19, such as fever, cough or shortness of breath.

In mild to moderate cases of coronavirus, a loss of smell and taste is emerging as one of the most unusual early signs of Covid-19.

"What's called anosmia, which basically means loss of smell, seems to be a symptom that a number of patients developed," CNN Chief Medical Correspondent Dr. Sanjay Gupta told CNN anchor Alisyn Camerota on New Day.

"It may be linked to loss of taste, linked to loss of appetite, we're not sure -- but it's clearly something to look out for," Gupta said. "Sometimes these early symptoms aren't the classic ones."

"Anosmia, in particular, has been seen in patients ultimately testing positive for the coronavirus with no other symptoms," according to the American Academy of Otolaryngology-Head and Neck Surgery.

A recent analysis of milder cases in South Korea found the major presenting symptom in 30% of patients was a loss of smell. In Germany, more than two in three confirmed cases had anosmia.

It has long been known in medical literature that a sudden loss of smell may be associated with respiratory infections caused by other types of coronaviruses, so it wasn't a surprise that the novel coronavirus would have this effect, according to ENT UK (PDF), a professional organization representing ear, nose and throat surgeons in the United Kingdom.

Is there anything you can do at home to test to see if you're suffering a loss of smell? The answer is yes, by using the "jellybean test" to tell if odors flow from the back of your mouth up through your nasal pharynx and into your nasal cavity. if you can pick out distinct flavors such as oranges and lemons, your sense of smell is functioning fine.

For some people, extreme fatigue can be an early sign of the novel coronavirus. The WHO report found nearly 40% of the nearly 6,000 people with laboratory confirmed cases experienced fatigue.

Just a few days into his quarantine, Cuomo was already exhausted by the fevers and body aches the disease brings.

"I'm so lethargic that I can stare outside, and, like, an hour-and-a-half goes by," Cuomo told Gupta on Anderson Cooper 360. "I think I took a 10-minute nap, and it was three and a half hours."

Fatigue may continue long after the virus is gone. Anecdotal reports from people who have recovered from Covid-19 say exhaustion and lack of energy continue well past the standard recovery period of a few weeks.

The WHO report also found nearly 14% of the almost 6,000 cases of Covid-19 in China had symptoms of headache and sore throat, while almost 5% had nasal congestion.

Certainly not the most common signs of the disease, but obviously similar to colds and flu. In fact, many symptoms of Covid-19 can resemble the flu, including headaches and the previously mentioned digestive issues, body aches and fatigue. Still other symptoms can resemble a cold or allergies, such as a sore throat and congestion.

Most likely, experts say, you simply have a cold or the flu -- after all, they can cause fever and cough too.

"At this moment, the current guidance -- and this may change -- is that if you have symptoms that are similar to the cold and the flu and these are mild symptoms to moderate symptoms, stay at home and try to manage them" with rest, hydration and the use of fever-reducing medications, said the AMA's Harris.

That advice does not apply if you are over age 60, since immune systems weaken as we age or if you are pregnant. Anyone with concerns about coronavirus should call their healthcare provider, according to the CDC.

It's unclear whether pregnant women have a greater chance of getting severely ill from coronavirus, but the CDC has said that women experience changes in their bodies during pregnancy that may increase their risk of some infections.

In general, Covid-19 infections are riskier if you have underlying health conditions such as diabetes, chronic lung disease or asthma, heart failure or heart disease, sickle cell anemia, cancer (or are undergoing chemotherapy), kidney disease with dialysis, a body mass index (BMI) over 40 (extremely obese) or an autoimmune disorder.

"Older patients and individuals who have underlying medical conditions or are immunocompromised should contact their physician early in the course of even mild illness," the CDC advises.

To be clear, you are at higher risk -- even if you are young -- if you have underlying health issues.

"People under 60 with underlying illnesses, with diabetes, heart disease, immunocompromised or have any kind of lung disease previously, those people are more vulnerable despite their younger age," Schaffner said.

A history of travel to an area where the novel coronavirus is widespread (and those parts of the world, including the US, are going up each day) is obviously another key factor in deciding if your symptoms may be Covid-19 or not.

If you have no symptoms, please don't ask for testing or add to backlog of calls at testing centers, clinics, hospitals and the like, experts say.

"We do not test people with no symptoms because it's a resource issue," Schaffner said about the assessment center at Vanderbilt. "However, we are emphasizing that people who have this small cluster of important symptoms -- fever and anything related to the lower respiratory tract such as cough and difficulty breathing -- reach out to be evaluated."

If you do have those three signs, where should you go?

"If you have insurance and you're looking for a provider or someone to call or connect with, there's always a number on the back of your insurance card; or if you go online, there is information for patients," Harris said.

"If you don't have insurance, you can start with the state health department or the local community health centers, those are officially known as federally qualified health centers," Harris advised, adding that some states have a 1-800 hotline number to call.

"If there is a testing and assessment center near you, you can go there directly," Schaffer said. "It's always good to notify them that you're coming. Otherwise, you need to call your healthcare provider and they will direct you what to do."

CNN's Jacqueline Howard contributed to this report.

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Small town Doctor…finds solutions to the big issues – Pontiac Daily Leader

Tuesday, April 7th, 2020

The medical community at large is now faced with a new dimension of medicine they have never encountered. As this health crisis that is ever changing, they find themselves with greater challenges than they have ever imagined. Due to shortages on PPE and expecting greater needs for it, and with the unknown factors of what the coming months may unfold. For independent practices it poses even more obstacles as they do not have the infrastructure of the larger hospitals or a group practice might have. Such is the case of a small town doctor that has chosen a different path of medicine from her start in Olney, Illinois.

Since Dr. Jill Scherer's practice began, some might think her model is unorthodox as she chose not to bill insurance, but operates on a direct billing system instead. Dr. Scherer reports The monthly membership fee has worked well and has been well received. Patients who cannot afford insurance can at least be offered primary care services. Other patients with stellar insurance love that their appointments are on time, for however much time they need, and they have access to their provider. My practice was full within 8 months, so I would say the community.

Scherers innovative thinking brought forth a creative solution to the lack of PPE availability presently. Seeing the medical community using some old phone booth looking devices where the individual was swabbing in the booth and sticking only their arms out to swab the person gave her some insight. It also gave the problem that came from the test itself, as it goes deep into the nasal passage which can cause a reflux reaction, then can trigger a response that can cause risk. Henceforth the tent came up outside her clinic and her brainchild came to life. She gave the basic explanation as such. Notoriously they sneeze or cough, so the plexiglass provides excellent protection. My husband, and engineer, decided, why not make a testing site through the window in my exam room. That way, the patient is outside and I am inside with the barrier of plexiglass. There is a stethoscope and giant rubber gloves that protrude from the plexiglass to examine the patient from the plexiglass to exam the patient with. I can swab a patient and be shielded. Then everything is sanitized with bleach before the next patient. Her ingenuity saves on the precious commodity of PPE, and she can judiciously screen her patients she shared. If needed, patients can still enter the clinic, and proper disinfection is provided. She has used the method of patients if needed remaining in their car as well on occasions.

When asking Dr. Scherer how our local community at large is doing in regards to the recommendations the CDC has given to COVID-19, shared these thoughts in regards to reaching a better outcome. I think we need to really take the shelter in place order seriously. Grocery shop once every 2 weeks. We need to wash our hands diligently. We need to not meet up with friends or have play dates. We are a small community and we dont want to be a hot spot for the virus. While it might not seem as scary because we are not Chicago or New York, we still need to be diligent and adhere to the social distancing, shelter in place, washing hands.

The CDC and other health officials have made recommendations in terms of wearing masks for the general public, Dr. Scherer gave these thoughts in relation to these coming guidelines as well As for fabric masks, I think we will see a change in the recommendations from health officials. Much of Asia uses masks and have much lower transmission than use.

Now we do not have enough commercial grade masks for the healthcare workers let alone enough for the general population, so I do think that cotton masks will be beneficial. As of now, any tightly woven cotton or polyblend cotton will be enough. These masks will prevent the wearer from spreading his/her own germs. It doesnt necessarily protect the wearer from getting the virus, but it does make the wearer conscious of how many times they touch their face. If the wearer coughs and sneezes, it does help prevent the respiratory droplets from being expelled into the air.

As there have been various statements in regards to use of Ibuprofen during this health crisis, and the use of it, in the course of the interview Dr. Scherer her thoughts. Her recommendations were as follows. I have not read any solid data on no ibuprofen or other NSAIDs, but I know that the general recommendation is to not use them if you have fever, coughing, cold symptoms. Stick with acetaminophen. If you are on daily NSAIDs, you should call your doctor for specific recommendations regarding stopping or when to stop

As Dr. Scherer incorporates some holistic approaches to what might she suggest or preventive measures, she gave these insights. Eating a healthy diet with fruits and vegetables will promote the best immune function. Thirty minutes of daily exercise as a minimum. Getting adequate sleep, 7-8 hours per night. Shutting off social media and the news for several hours per day to decrease stress level might also help.

In terms of mental health in general terms these suggestions during these stressful times, she gave some excellent helpful tips that all ages can incorporate to aid in the balance as we are all trying to find a new normal. Find a way, while respecting social distancing, to do something nice for someone else. Practicing mindfulness or meditation can help calm anxious nerves. We know that exercise can be as powerful as antidepressants for anxiety and depression, get out and exercise. Sunshine, when it peaks out of the clouds, can also help with our mood.

Her practice is like many all across the country that are finding new ways to treat their patients. She had already used telemedicine as an option, due to not billing insurance prior to COVID. Her patients are able to call, text, or have video chats routinely as well. She routinely has three platforms she is able to utilize, so if one is not working well, she can use another one that works better for that particular patient.

As COVID-19, is only one area of health concerns for our community, I asked this very down to earth and caring physician how she thought our area could improve the total well being in general. She gave some great input. I stress in my practice, the need for lifestyle medicine. We should be using diet, nutrition, stress management, good sleep to help combat our leading causes of death like heart disease, high blood pressure, and diabetes. My advice is not always welcomed, but at least patients know they have a choice in their health outcomes for a majority of diseases.

When asked for her best advice for our area in terms of addressing this ever changing and concerning health crisis upon us she shared these final insights. My goal right now is to take the best care of my patients especially during COVID19 because the rest of health conditions didnt take a break when COVID-19 got here. There are still ear infections, heart attacks, etc. So my immediate goal is to provide excellent care even with the pandemic. My long term goals

are put on hold right now, I will be patient and see how things are in 6-9 months. I think people should know that I am a small business owner trying to provide the best in a strange situation. I want to protect myself and my patients. I dont want to be a super spreader of COVID-19, and that is why I have changed the way I see people. Yes, their visit will be on the phone, then in the parking lot. Only if truly needed will it be in person and at that time, I will look like I have hazmat gear on. I might look a little nutty, but I want to be alive to care for my patients, I dont want to bring COVID-19 home to my family, and I dont want to spread it to my patients. Direct primary care, membership medicine, allows me to be flexible and keep everyone as safe as possible.

Scherer grew up in Streamwood, Illinois, and attended the University of St. Francis in Joliet, Illinois. After completing her bachelor's of science in Biology, she earned her Doctor of Medicine at Loyola University Stritch School of Medicine. She completed her training at the Waukesha Family Medicine Residency in Waukesha, Wisconsin, specializing in Family Practice. Dr. Scherer most recently practiced at the Richland Medical Center in Richland Center, Wisconsin, providing general family practice, obstetrical care, inpatient hospital care, and urgent care. Her areas of interest are preventative medicine, lifestyle medicine, and lactation/breastfeeding medicine. Her continuing education focuses on lifestyle medicine and she will have board certification in it by fall 2018. She is an International Board Certified Lactation Consultant, IBCLC.

Dr. Scherer and her husband, Mark, recently moved to Olney, Illinois to be closer to his family as they raise their two children. She is thrilled to be practicing in the community and helping to improve the lives of her patients.

It was a rare and refreshing experience, to meet a physician who is dedicated completely to the calling of medicine in its truest sense. She is indeed a great asset to our community. She is accepting patients and can be reached at 618-746-2676 her practice, Whole Family Health Medical Clinic is at 131 Boone St. in Olney, Illinois. The clinic has a facebook page, might note Dr. Scherer, has routine posts on COVID-19 with current updates for the community as well.

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Small town Doctor...finds solutions to the big issues - Pontiac Daily Leader

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Worse Than Anything Weve Ever Seen: Frontline Doctors Race to Learn the Mysteries of a Deadly Virus – Vanity Fair

Tuesday, April 7th, 2020

As the official U.S. death toll from COVID-19 passed 10,000, Surgeon General Jerome Adams warned that Americans should brace for the hardest and saddest week of their lives. During a press appearance over the weekend, he called the coming days our Pearl Harbor moment, our 9/11 moment. Inside New Yorkarea hospitals, the prospects match his grim tone. In addition to struggling with widely-reported supply shortages, working seemingly endless shifts, and struggling to manage the influx of patients, infectious disease experts say that even as theyre racing to develop an effective vaccine, they are essentially learning on the job.

The infection itself does have some perplexing features, said Dr. Megan Coffee, a clinical assistant professor at the NYU Grossman School of Medicine specializing in infectious diseases and immunology, who coauthored a study about an experimental A.I. tool that predicts which patients with the virus will develop a serious respiratory illness. She listed just a few of the many unanswered questions: We dont yet know what we can do to prevent this immunologic response. We also dont fully understand why some, who are healthy, go on to have severe disease and others, with more risk, do not.

Specific characteristics of the virus likewise remain a mystery. The pandemic of 1918was associated with bacterial as well as viral pneumonia, which does not seem to be the case with the novel coronavirus, said Dr. Joseph M. Vinetz, a professor at Yale School of Medicine who also specializes in infectious diseases. But we still dont know whether coronavirus can lead to secondary or superimposed bacterial pneumonia in addition to [causing] immune damage to the lungs, which is the primary cause of severe illness and death. This coronavirus, he said, is puzzling due to its unique combination of asymptomatic infectiousness, and the delayed onset of severe disease. Very perplexing.

Dr. Sandra Gelbard, a Manhattan-based internist who specializes in preventative medicine and one of the first doctors in New York City to begin COVID-19 testing, described the current epidemic as way, way more concerning than the first two coronavirusesSARS and MERSwhich is surprising because the first two were more lethal. But those viruses were contained. With this novel coronavirus, 25 to 50% walk around without symptoms. It is the right combination of lethality and transmissibility. This makes this virus a real global threat.

Dr. Coffee concurred. This is the disease weve always feared as infectious disease doctorsa respiratory-borne virus that spreads easily person-to-person, but with a high mortality, she said. Those of us who have worked on Ebola and other crises have feared for a while [that] this would be worse than anything we have ever seen.

The results, said Dr. Gelbard, could be more devastating than current predictions suggest. If we did intense social isolation like they did in China and South Korea, the number might have been around [100,000 deaths], but we missed the boat on that, she said. I dont expect it to be 100,000 to 200,000 people dead. It could easily be 1 million.

She added, we really dont know the mortality of this virus. Were assuming at best its somewhere around the 1% mark. We cant know at this point. No one knows.

Meanwhile, as it spreads, the virus is changing. The issue is that [it] is mutating, said a New York Citybased doctor treating COVID-19 patients. We cannot predict what strain it will mutate to, and in some populations strains may be more virulent than others, so all we can do is prepare for the worst. She added, Its scary because it is a disease that is ever-evolving. Just when we think we have figured out the pathophysiology of the disease process and how to manage it effectively, we realize there is a new loophole or nuance that the disease presents us with.

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Worse Than Anything Weve Ever Seen: Frontline Doctors Race to Learn the Mysteries of a Deadly Virus - Vanity Fair

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Cats may get coronavirus, but it’s nothing to worry about – The Philadelphia Tribune

Tuesday, April 7th, 2020

A newly hatched study out of China, so raw that its not yet been peer-reviewed, has some disturbing news for cat lovers.

Our furry feline friends appear to be susceptible to catching COVID-19, the disease caused by the coronavirus called SARS-CoV-2. Even worse, the cats in the study were able to infect each other, although they showed no signs of illness.

Ferrets were also able to catch the virus, although it didnt appear to harm them. Dogs, on the other hand, were not susceptible, according to the study. The virus showed up in the feces of five dogs, but no infectious virus was found. Pigs, chickens and ducks were also not very hospitable places for the virus.

But theres no need for cat or ferret lovers to panic, experts say. Theres no evidence their pets could get very sick or die from the novel coronavirus.

Yes, people should embrace their pets. These researchers squirted the virus down the cats nose in high concentration, which is pretty artificial, said Dr. John Williams, chief of the division of pediatric infectious diseases at the University of Pittsburgh Medical Center Childrens Hospital of Pittsburgh.

The lab experiment used a scenario that is completely unrealistic, experts say. First, researchers forced extremely high doses of virus up the nostrils of five 8-month-old domesticated cats.

Cats in our homes or even in the wild would never be exposed to that level of virus.

Thats a whole lot more than an average human would get, said infectious disease expert Dr. William Schaffner, a professor of preventative medicine and infectious disease at Vanderbilt University School of Medicine in Nashville.

So this is an artificial circumstance and we dont know that it happens in nature at all, Schaffner added.

Two of the five cats were euthanized six days later. Researchers found virus particles in their upper respiratory systems.

The remaining three infected cats were put into a cage adjacent to three non-infected cats. One of those three cats later tested positive for the virus, while the other two did not. Still, the researchers felt that showed the virus could be transmitted via respiratory drops.

Or did it? None of the infected cats exhibited signs of illness. And even if they did pass the virus to each other, that doesnt mean they would be able to pass it on to humans.

Thats what happened nearly two decades ago with a sister coronavirus called SARS-CoV, which causes the deadly pneumonia-like respiratory disease called SARS.

Just like now, science found cats could be infected with SARS-CoV and infect other cats. But the virus didnt transmit widely among house cats during the 2002 to 2004 pandemic, nor were there any known cases of transmission to humans.

The study found ferrets were also efficient replicators of the virus meaning that the virus can easily grow and reproduce in their long, slinky bodies.

SARS-CoV-2 can replicate in the upper respiratory tract of ferrets for up to eight days, without causing severe disease or death, the study said. The study did not look at a longer time frame.

Thats good news for researchers looking for a way to test any future vaccines for SARS-CoV-2, also called the novel coronavirus.

Its necessary to have an animal model to do initial tests of vaccines and understand how viruses cause disease. So, this will be useful to the field, Williams said.

Its actually not surprising that ferrets appear to respond to the novel coronavirus. A ferrets lung and airways are strikingly similar to a humans. In fact, biologically and physiologically ferrets are more similar to humans than they are to a mouse or rat.

Ferrets are classical animals in which to study influenza its been done for decades, Schaffner said. If scientists were looking for an animal model, they would reach for the ferrets first.

Will your cat or ferret come down with coronavirus? Highly unlikely, experts say, pointing to the fact that we would certainly have heard of many cases in pets by now, considering the significant spread of the virus in the us and Europe.

Hong Kong has been quarantining animals belonging to people diagnosed with COVID-19 and have found only two cases of positive results in dogs. The dogs showed no signs of illness during the quarantine.

Rare as it may be, it appears one cat in Belgium may have gotten the virus in March from her owner, who was ill with COVID-19 after returning from a visit to Italy. But even though the cat had respiratory problems and high levels of the virus in vomit and feces, researchers arent yet sure if the cat was sick from COVID-19 or another illness.

While 2 dogs (Hong Kong) and 1 cat (Belgium) have been reported to have been infected with SARS-CoV-2, infectious disease experts and multiple international and domestic human and animal health organizations agree there is no evidence at this point to indicate that pets spread COVID-19 to other animals, including people, the American Veterinary Medical Association says on its website.

The AVMA and the us Centers for Disease Control and Prevention recommend taking normal precautions when cleaning litter boxes and feeding animals.

Out of an abundance of caution, the AVMA suggests anyone ill with COVID-19 symptoms limit contact at this time, until more information is known about the virus.

Have another member of your household take care of walking, feeding, and playing with your pet, the AVMA states. If you have a service animal or you must care for your pet, then wear a facemask; dont share food, kiss, or hug them; and wash your hands before and after any contact with them.

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Hydroxychloroquine evaluated to treat, prevent COVID-19: University of Pennsylvania trial – Outbreak News Today

Tuesday, April 7th, 2020

A new trial led by the Perelman School of Medicine at the University of Pennsylvania will evaluate whether the drug hydroxychloroquine (HCQ) can benefit people infected with COVID-19, as well as whether taking the drug preventatively may help people avoid infection altogether. The study, called Prevention and Treatment of COVID-19 with HCQ (PATCH), is currently enrolling patients in three separate sub-studies (NCT04329923).

PATCH sub-study 1 will evaluate HCQ compared to placebo in infected patients who are quarantined at home. PATCH sub-study 2 will evaluate high dose compared to low dose HCQ in hospitalized patients. PATCH sub-study 3 will evealuate HCQ compared to placebo prophylactically in health care workers working with COVID-19 patients to evaluate whether it can prevent infection. Sub-studies 1 and 3 are double-blind placebo controlled studies, meaning neither the patient nor the doctor will know whether they are taking HCQ or placebo until the end of the study. Importantly, if the patient or health care worker starts getting worse, they can be unblinded, and the trial allows crossover to HCQ if the patient was assigned placebo.

We know HCQ can be an effective anti-viral in a lab setting, but despite recent public conversation, there is no definitive evidence it can work in humans infected with COVID-19. It is our hope that this trial will provide critical evidence as to whether this drug may be effective in combating the current pandemic, said the studys principal investigator Ravi K. Amaravadi, MD, an associate professor of Hematology-Oncology who has spent his career studying HCQ and related compounds.

For this trial, Amaravadi is working with a multidisciplinary team at Penn, including Benjamin S. Abella, MD, MPhil, a professor of Emergency Medicine, and Ian D. Frank, MD, associate chief of Infectious Diseases, as well as colleagues in Pathology and Laboratory Medicine, Cardiology, Statistics, and the Abramson Cancer Center.

The first sub-study of the trial will test HCQ in patients who are infected and are well enough to go home, but who need to be in quarantine. Quarantine can be prolonged for some people who have a worse case of the illness, and can impose significant economic, emotional, and psychological hardship on the patient and his or her family. Family members living with a quarantined COVID-19 patient are at high risk of getting the disease themselves. In order to be released from quarantine, they must meet certain criteria according to the Centers for Disease Control (CDC): patients must go 72 hours without a fever, see their symptoms improve, and go seven days since their symptoms first appeared. The primary goal of PATCH sub-study 1 is to find out whether the drug reduces the number of days the patient stays quarantined. Researchers were forced to overcome unique logistical hurdles, including arranging for virtual consents from patients and home delivery of HCQ doses.

The second sub-study of the trial will test HCQ in patients who are hospitalized with COVID-19 to see if it can reduce the time to discharge. Patients in this group will also be randomized into a high dose or low dose group. No one will receive a placebo. The correct dose of HCQ for treating COVID-19 is not currently known and this study will provide valuable information to answer that question. The third sub-study will test whether HCQ can work as a preventative medicine to stop infection in health care workers at risk of exposure to COVID-19. Researchers plan to enroll 200 workers in the sub-study.

The need for the third sub-study here is critical, as we try to keep the people working on the front lines of this pandemic healthy so they can continue to keep the nations health care infrastructure up and running, Abella said.

Given the rapid spread of the virus, researchers had to work quickly not only to organize the trial and get it approved from a regulatory standpoint, but also to solve practical problems. In the span of less than a month, they were able to secure funding, arrange for a donation of HCQ, and partner with a group to manufacture an appropriate placebo. The researchers say they are grateful to their partners, and also to their leadership for the support that helped it all come together.

This is an unprecedented time, and it will take unprecedented cooperation, resources, and leadership to get through it. This trial shows Penns ability to step up to meet that responsibility and investigate the scientific questions the world desperately needs to answer, said J. Larry Jameson, MD, PhD, dean of the Perelman School of Medicine.

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Study: Cats may get coronavirus, but experts say its nothing to worry about – KSAT San Antonio

Tuesday, April 7th, 2020

(CNN) -- A newly-hatched study out of China, so raw that it's not yet been peer-reviewed, has some disturbing news for cat lovers.

Our furry feline friends appear to be susceptible to catching Covid-19, the disease caused by the coronavirus called SARS-CoV-2. Even worse, the cats in the study were able to infect each other, although they showed no signs of illness.

Ferrets were also able to "catch" the virus, although it didn't appear to harm them. Dogs, on the other hand, were not susceptible, according to the study. The virus showed up in the feces of five dogs, but no infectious virus was found. Pigs, chickens and ducks were also not very hospitable places for the virus.

But there's no need for cat or ferret lovers to panic, experts say. There's no evidence their pets could get very sick or die from the novel coroneavirus.

"Yes, people should embrace their pets. These researchers squirted the virus down the cats nose in high concentration, which is pretty artificial," said Dr. John Williams, chief of the division of pediatric infectious diseases at the University of Pittsburgh Medical Center Children's Hospital of Pittsburgh.

No realistic exposure

The lab experiment used a scenario that is completely unrealistic, experts say. First, researchers forced extremely high doses of virus up the nostrils of five 8-month-old domesticated cats.

Cats in our homes or even in the wild would never be exposed to that level of virus.

"That's a whole lot more than an average human would get," said infectious disease expert Dr. William Schaffner, a professor of preventative medicine and infectious disease at Vanderbilt University School of Medicine in Nashville.

"So this is an artificial circumstance and we don't know that it happens in nature at all," Schaffner added.

Two of the five cats were euthanized six days later. Researchers found virus particles in their upper respiratory systems.

The remaining three infected cats were put into a cage adjacent to three non-infected cats. One of those three cats later tested positive for the virus, while the other two did not. Still, the researchers felt that showed the virus could be transmitted via respiratory drops.

Or did it? None of the infected cats exhibited signs of illness. And even if they did pass the virus to each other, that doesn't mean they would be able to pass it on to humans.

That's what happened nearly two decades ago with a sister coronavirus called SARS-CoV, which causes the deadly pneumonia-like respiratory disease called SARS.

Just like now, science found cats could be infected with SARS-CoV and infect other cats. But the virus didn't transmit widely among house cats during the 2002 to 2004 pandemic, nor were there any known cases of transmission to humans.

Ferrets affected too

The study found ferrets were also "efficient" replicators of the virus -- meaning that the virus can easily grow and reproduce in their long, slinky bodies.

"SARS-CoV-2 can replicate in the upper respiratory tract of ferrets for up to eight days, without causing severe disease or death," the study said. The study did not look at a longer time frame.

That's good news for researchers looking for a way to test any future vaccines for SARS-CoV-2, also called the novel coronavirus.

"It's necessary to have an animal model to do initial tests of vaccines and understand how viruses cause disease. So, this will be useful to the field," Williams said.

It's actually not surprising that ferrets appear to respond to the novel coronavirus. A ferret's lung and airways are strikingly similar to a human's. In fact, biologically and physiologically ferrets are more similar to humans than they are to a mouse or rat.

"Ferrets are classical animals in which to study influenza -- it's been done for decades," Schaffner said. "If scientists were looking for an animal model, they would reach for the ferrets first."

What this means

Will your cat or ferret come down with coronavirus? Highly unlikely, experts say, pointing to the fact that we would certainly have heard of many cases in pets by now, considering the significant spread of the virus in the US and Europe.

Hong Kong has been quarantining animals belonging to people diagnosed with Covid-19 and have found only two cases of positive results in dogs. The dogs showed no signs of illness during the quarantine.

Rare as it may be, it appears one cat in Belgium may have gotten the virus in March from her owner, who was ill with Covid-19 after returning from a visit to Italy. But even though the cat had respiratory problems and high levels of the virus in vomit and feces, researchers aren't yet sure if the cat was sick from Covid-19 or another illness.

"While 2 dogs (Hong Kong) and 1 cat (Belgium) have been reported to have been infected with SARS-CoV-2, infectious disease experts and multiple international and domestic human and animal health organizations agree there is no evidence at this point to indicate that pets spread COVID-19 to other animals, including people," the American Veterinary Medical Association says on its website.

The AVMA and the U.S. Centers for Disease Control and Prevention recommend taking normal precautions when cleaning litter boxes and feeding animals.

"Out of an abundance of caution," the AVMA suggests anyone ill with COVID-19 symptoms limit contact at this time, "until more information is known about the virus."

Have another member of your household take care of walking, feeding, and playing with your pet, the AVMA states. If you have a service animal or you must care for your pet, then wear a facemask; dont share food, kiss, or hug them; and wash your hands before and after any contact with them.

The-CNN-Wire & 2020 Cable News Network, Inc., a WarnerMedia Company. All rights reserved.

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Why we should all start making our own face masks during coronavirusand an expert-approved guide on how – CNBC

Tuesday, April 7th, 2020

During the early days of the coronavirus pandemic, the U.S. Centers for Disease Control and Prevention andWorld Health Organization made it clear that, unless you're sick or are a medical professional, you do not need to wear a face mask.

On February 29th, U.S. Surgeon General Jerome Adams tweeted:"Seriously people- STOP BUYING MASKS! They are NOT effective in preventing general public from catching #Coronavirus, but if healthcare providers can't get them to care for sick patients, it puts them and our communities at risk!"

Adams' message comes with good intentions. With COVID-19 cases soaring, doctors, nurses and other frontline health-care workers confront a severe shortage of masks and cautioning people against buying them can help offset the problem.

Butother countries have already taken aggressive measures to prevent the spread of COVID-19 by telling citizens to wear masks, even if the masksare homemade.

Last week, George Gao,director-general of the Chinese Center for Disease Control and Prevention, told ScienceMag.comthat the "big mistake in the U.S." is that people aren't wearing masks. "This virus is transmitted by droplets and close contact. Droplets play a very important role," he said. You've got to wear a mask, because when you speak, there are always droplets coming out of your mouth."

Gao has done significant research on virusesthat have fragile lipid membranes called envelopes a group that includes SARS-CoV-2 (the virus that causes COVID-19) and how they enter cells and move between species.

"Many people have asymptomatic or presymptomatic infections," he continued. "If they're wearing face masks, it can [help] prevent droplets that carry the virus from escaping and infecting others."

So far, U.S. health officials have not offered guidelines or regulations around homemade masks and since commercially made ones are almost impossible to find, your last resort is just starting making your own.

You can find a variety of mask designs online, but simple yet promising one comes from a recent study published in the medical journal Disaster Medicine and Public Health Preparedness.

Researchers analyzed 2008 studiesfrom Public Health England(which evaluated a range of household materials that, in the event of a pandemic, could be used by the general public to make masks) to create a D.I.Y. guide.

"These studies found that T-shirts and pillowcases made into a mask using the design [below] may act as a barrier against influenza, or help limit spread by a person with symptoms," according to the study's authors. "We have no data on COVID-19, but it's not unreasonable to assume similarity."

They also stressed that "the wearing of face masks will only offer limitedprotected, and should notbe considered as sufficient protection. Additional preventative measures need to be adopted."

Face mask template:

(Template and instructions C/O:Disaster Medicine and Public Health Preparedness. Click here to enlarge.)

Supplies:

Simplified version of step-by-step instructions:

Important reminders:

Most people have the basic materials tomake a mask right now. It's time to call forth the "can do" American spirit and encourage people stuck at home to start sewing.

Doing so can save existing stock for healthcare professionals as manufacturers ramp up production in the coming months. If you're healthy have any unused commercial or medical-grade masks lying around, consider donating them to local hospitals.

Instead of obsessing over ill-conceived mixed messages, let's starting viewing mask-wearing as an act of solidarity and make it the new norm (at least until this pandemic over).

Nir Eyalis a behavioral psychology expert and instructor at Stanford's Graduate School of Business. He is the author of the best-selling books"Indistractable: How to Control Your Attention and Choose Your Life"and "Hooked: How to Build Habit-Building Products" andhas written for Harvard Business Review, TIME and Psychology Today. Follow him on Twitter @NirEyal.

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Why we should all start making our own face masks during coronavirusand an expert-approved guide on how - CNBC

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Henry Ford Health System to Lead Nat’l Study of Drug’s Effectiveness vs. COVID-19 – The National Herald

Tuesday, April 7th, 2020

Dr. Steven Kalkanis, CEO of the Henry Ford Medical Group. (Photo: Courtesy of the Henry Ford Medical Group)

DETROIT According to a news release dated April 2, Henry Ford Health System will lead the first large-scale study in the United States of the effectiveness of an anti-malarial drug in preventing COVID-19 in healthcare workers and first responders who volunteer to participate.

The study of hydroxychloroquine used prophylactically could begin as early as next week, after a plea to the federal government by Detroit Mayor Michael Duggan and Metro Detroit healthcare experts.

This is going to be the first major, definitive study in healthcare workers and first responders of hydroxychloroquine as a preventative medication, said the studys organizer, Henry Ford Health Systems Dr. William W. ONeill, a world-renowned interventional cardiologist and researcher who has pioneered multiple treatments for heart disease. There has been a lot of talk about this drug, but only a small, non-blinded study in Europe. We are going to change that in Metro Detroit and produce a scientific answer to the question: Does it work?

Participation in the study is strictly on a volunteer basis. Greek-American Dr. Marcus Zervos, division head of Infectious Disease for Henry Ford Health System, will oversee this study with Dr. ONeill.

We are glad to see Henry Fords lead on this volunteer study that could help protect medical workers and first responders across southeast Michigan, Mayor Duggan said, acknowledging U.S. Food & Drug Administration Commissioner Dr. Stephen M. Hahn. I also deeply appreciate Dr. Hahns prompt support for this important effort.

Both health care workers and first responders will be enrolled at Henry Ford Hospital Detroit. Currently, there are no FDA-approved therapies to prevent or treat COVID-19. According to the U.S. Centers for Disease Control & Prevention, hydroxychloroquine (also known as hydroxychloroquine sulfate) is an FDA-approved arthritis medicine that also can be used to prevent or treat malaria. It is available in the United States by prescription only. The drug is sold under the brand name Plaquenil and it is also sold as a generic medicine. It is commonly used by patients with arthritis, lupus or other rheumatic conditions.

Metro Detroit has a history of stepping up when things get tough, said Dr. Adnan Munkarah, Henry Ford Health System Executive Vice President and Chief Clinical Officer. We have a commitment to do that right now to look at all options in a scientific way in the face of this worldwide pandemic.

The study, titled WHIP COVID-19 Study, is a 3,000+ subject look at whether the drug prevents front-line workers from contracting the virus. Once they provide a blood sample, the study subjects will receive vials with unidentified, specific pills to take over the next eight weeks: a once-a-week dose of hydroxychloroquine, a once-a-day dose, or a placebo (a pill that looks like the medication, but does not contain any medication or other active ingredients). The study medication was specially procured for this study and will not impact the supply of medication for people who already take the medication for other conditions.

Participants will not know what group they are in. They will then be contacted weekly and in person at week 4 and week 8 of the study to see if they are exhibiting any symptoms of COVID-19, including dry cough, fever or breathing issues, as well as any medication side effects. At eight weeks, they will be checked again for symptoms, medication side effects, and have blood drawn. Results will be compared among the three groups to see if the medication had any effect.

Given our broad clinical trials and translational research infrastructure, we are grateful to bring this type of large-scale effort to the COVID-19 battle, said Greek-American Dr. Steven Kalkanis, CEO, Henry Ford Medical Group and Senior Vice President and Chief Academic Officer of Henry Ford Health System. We see the heroics of the frontline responders in healthcare, public safety and service. Henry Ford Health System is poised to do anything we can to help them stay safe.

The FDA will provide the drug directly to Henry Ford Health System physicians to distribute. Recruiting has not yet begun. More information can be found at http://www.HenryFord.com/whipCOVID19.

The CDC describes hydroxychloroquine, which has been used for 75 years, as a relatively well-tolerated medicine. The most common adverse reactions reported are stomach pain, nausea, vomiting, and headache. These side effects can often be lessened by taking hydroxychloroquine with food. Hydroxychloroquine may also cause itching in some people. Minor side effects such as nausea, occasional vomiting, or diarrhea usually do not require stopping the antimalarial drug. Although rare, serious side effects can occur while taking this medication.

If the study finds the drug effective as a preventative medication for COVID-19, it is possible that the study could expand to include hydroxychloroquine in other COVID-19 treatment options, the doctors said. Henry Ford Health System doctors are prescribing hydroxychloroquine as an off-label treatment for only hospitalized COVID-19 positive patients who meet specific criteria as outlined by the hospital systems Division of Infectious Diseases. As required by the state of Michigans Department of Licensing and Regulatory Affairs, the physicians are documenting the prescribed use in the patients electronic medical record.

Henry Ford, as one of the regions major academic medical centers with more than $100 million in annual research funding, is already involved in numerous COVID-19 trials with partners around the world. Henry Ford is also becoming involved in an Abbott-led study of a rapid, point-of-care test for COVID-19. The equipment, about the size of a toaster, delivers positive results in as little as five minutes and negative results in 13 minutes.

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The Ayurvedic approach to immunity and the coronavirus – Thrive Global

Tuesday, April 7th, 2020

By Dr. Hemant Gupta DaYM, BAMS and Amita Nathwani, MA

Last week, Eric Garcetti, the mayor of Los Angeles, gave the people of his city a message regarding masks: if you really must go out on the street, for whatever reason, cover your mouth and nose. This measure was given to begin the first step to protecting ones self from the virus.

As we study the impact of stopping the virus outbreak trajectory, the question remains; what can we, as ordinary citizens do to stay healthy in the midst of the exposure?

Enhancing the bodys natural defense system plays an important role in maintaining optimum health and while there is no medicine for COVID-19 as of now, taking preventive measures to boost our immunity is what is called for in these times.

Ayurvedic Medicine, a 5,000 year-old approach to health, which addresses both pathology and prevention, says it starts in the gut. Without a strong and healthy digestive system, with balanced flora and the necessary enzymes to help break down pathogens, our first line of defense is compromised.

Ayurveda has a number of immune building formulas which are recommended to support the immune system. It is important to note, however, Ayurvedas fundamental approach in using plants as medicine is that the individual person as a whole is who advocates the use of herbs instead of isolating, extracting, and administering active ingredients. Ayurveda supports the synergistic approach as opposed to the reductionist approach of each plant.

Before we get to the considerations of the intake of any formula or supplement capable of increasing immunity or fighting disease, we must stress the importance of starting with supporting a weak digestion. Without this step, the efficacy of the remedies will remain low, and the body will not be able to fully breakdown the needed nutrients.

One of the methods of diagnosis by Ayurveda is to determine its weakness by looking at the tongue. If there is a white coating or film, we recommend the following preemptive steps:

These actions over a period of a couple of days will help to increase digestion and help the body begin its ability to receive therapeutic remedies for building the immune system and fighting pathogens. Without this step, the efficacy of the remedies will remain low, and the body will not be able to fully breakdown the needed nutrients.

The second stage of building immunity is to ensure that you are avoiding all causative factors. Studies show that reducing stress through meditation, staying active, yoga and breathing exercises can significantly reduce inflammation in the body and therefore increase the bodys resistance to pathogens and disease. Healthy eating and getting an adequate amount of sleep is also imperative for the bodys natural resistance to be sustained.

In addition to the recommended CDC guidelines for minimizing exposure, Ayurveda offers help in protecting the nose, mouth or eyes, the first entry point of the COVID-19 virus. It is recommended to follow these simple procedures that can be practiced on a daily basis.

And finally, once the digestion is strong, causative factors are eliminated and preventative measures are in place, we can start recommending herbal formulas.

The classic Ayurvedic formula called Chywanprash, serves as a general tonic to increase what Ayurveda calls Ojas or immune building substance in the body. The formula is broken down into about 50 ingredients that work synergistically. Its primary ingredient is the Amla Berry, or Emblica officinalis, which supports antioxidant activity via the encouragement of collagen and elastic production. This formula is available everywhere online in Ayurvedic stores, in both a fresh and dried form, depending on the health needs of the patient.

In this way, Amla supports both the health of the outer skin and the inner skin that lines the gut, respiratory tract, and all mucus membranes of the body. Amla is also well known as a source for natural Vitamin C. Along with other immuno-modulating active plant ingredients like Ashwagandha, Guduchi and Holy Basil, this formula works synergistically to promote health.

Founding professor of John Hopkins University, Sir William Oslar said it best, Let us not treat the disease, but let us treat the patient who has the disease.

Dr. Hemant Gupta is a renowned scholar, researcher and practitioner of Ayurvedic Medicine. Along with a degree in Natural Medicine, Dr. Gupta completed his Masters in Kayachikitsa (Internal Medicine) from National Institute of Ayurveda in Jaipur.

Amita Nathwani is a practitioner and professor with a Masters in Ayurvedic Medicine. She is an adjunct faculty member with the Dr. Andrew Weil Center for Integrative Medicine and a Public Voices Fellow with the OpEd Project.

More:
The Ayurvedic approach to immunity and the coronavirus - Thrive Global

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