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Archive for the ‘Arthritis’ Category

Updated 2019 ACR Recommendations for Rheumatoid Arthritis Disease Activity Measures – Rheumatology Advisor

Thursday, December 5th, 2019

A working group of rheumatologists and rheumatology professionals convened to update the American College of Rheumatology (ACR) recommendations for rheumatoid arthritis (RA) disease activity measures by identifying 11 measures that met the minimum standard and 5 that were preferred for regular use in clinical settings, according to a systematic literature review published in Arthritis Care & Research.1 Researchers examined articles published between January 2009 and January 2017 on the Ovid Medline, EMBASE, and Cochrane databases. Study details and psychometric properties were abstracted, and study quality was assessed by the Consensus-Based Standards for the Selection of Health Measurement Instruments 4-point scoring template. Psychometric properties for each RA disease activity measure were classified as strong, moderate, limited, conflicting, or unknown level of evidence

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Cialis splitting 20mg – Cancer specialists of north florida baptist south – Arthritis in hands and feet treatment – Laughlin Entertainer

Thursday, December 5th, 2019

Cialis splitting 20mg - Cancer specialists of north florida baptist south - Arthritis in hands and feet treatment   Laughlin Entertainer

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Drug Decreases Gut Leakiness Linked to Ulcerative Colitis – Technology Networks

Thursday, December 5th, 2019

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the guts epithelium. Affecting roughly 1 million Americans, ulcerative colitis is a chronic inflammatory bowel disease of the large intestine in which the lining of the colon becomes inflamed and leaky

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Tetra Therapeutics Announces Presentation of Data from Retrospective Population-Based Study of 56 Million Patients at the 12th Clinical Trials on…

Thursday, December 5th, 2019

GRAND RAPIDS, Mich.--(BUSINESS WIRE)--Tetra Therapeutics, a clinical-stage biopharmaceutical company developing novel treatments for patients with cognitive impairment and memory loss, today announced a poster presentation at the 12th Clinical Trials on Alzheimers Disease Meeting (CTAD) being held in San Diego, from December 4 7. The poster, titled Tumor Necrosis Factor (TNF) Blocking Agents Reduce Risk for Alzheimers Disease in Patients with Rheumatoid Arthritis and Psoriasis, highlights data from a retrospective population-based study of 56 million patients in which inflammatory disease in the body is shown to increase risk for Alzheimers disease and that risk can be reduced in these patients by treatment with a TNF blocking drug. The study was conducted in conjunction with Case Western Reserve University

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Drug decreases gut leakiness associated with ulcerative colitis – UC Riverside

Thursday, December 5th, 2019

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the guts epithelium. Affecting roughly 1 million Americans, ulcerative colitis is a chronic inflammatory bowel disease of the large intestine in which the lining of the colon becomes inflamed and leaky.

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Methotrexate Receives FDA Approval for Treatment of Rheumatoid Arthritis – Pharmacy Times

Tuesday, December 3rd, 2019

Officials from the FDA have approved methotrexate (RediTrex, Cumberland Pharmaceuticals) as an injection for the treatment of adult and pediatric patients with rheumatoid arthritis. The injection is also indicated for adults with psoriasis, according to the company.

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Novel Biomarker of Macrophage Activation Syndrome Identified in Juvenile Idiopathic Arthritis – Rheumatology Advisor

Tuesday, December 3rd, 2019

Certain levels of plasma protein adenosine deaminase 2 (ADA2) are sensitive and specific, and can be used as a novel biomarker of macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis (JIA), according to research results published in the Annals of the Rheumatic Diseases. Researchers sought to evaluate the role and function of ADA2 as a novel biomarker of macrophage activation syndrome because of the overlapping clinical features between macrophage activation syndrome and active systemic JIA

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Jingle Bake Sale To Benefit The Arthritis Foundation – Beverly, IL Patch

Tuesday, December 3rd, 2019

CHICAGO - About 54 million adults have doctor-diagnosed arthritis, according to The Arthritis Foundation. Almost 300,000 babies and children have arthritis or a rheumatic condition For Chelsea May, those numbers hit too close to home.

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Rates of Serious Infection Events Similar With Upadacitinib, Adalimumab in Rheumatoid Arthritis – Rheumatology Advisor

Tuesday, December 3rd, 2019

ATLANTA There is no significant difference in the rate of serious infections in patients with rheumatoid arthritis (RA) receiving upadacitinib 15 mg or adalimumab, according to study results presented at the 2019 American College of Rheumatology/Association of Rheumatology Professionals (ACR/ARP) Annual Meeting, held November 8 to 13, 2019, in Atlanta, Georgia. However, the results indicated that patients receiving upadacitinib 15 mg and 30 mg had higher rates of herpes zoster compared with patients receiving adalimumab or methotrexate.

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Kim Kardashian West’s battle with psoriatic arthritis: Will understanding the genetics of the autoimmune disorder point to a cure? – Genetic Literacy…

Tuesday, December 3rd, 2019

In September, the world of entertainment news buzzed with word that Kim Kardashian West tested positive for lupus and rheumatoid arthritis. The star underwent further tests, however, resulting in a diagnosis of psoriatic arthritis instead. While all three autoimmune disorders share some signs and symptoms, psoriatic arthritis is generally considered to have a better prognosis than lupus.

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Could a Knee Brace Help Ease Your Osteoarthritis Pain? – Health Essentials from Cleveland Clinic

Tuesday, December 3rd, 2019

While theres no cure for knee osteoarthritis, a combination of strategies can help relieve your pain and keep you active. Cleveland Clinic is a non-profit academic medical center.

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AbbVie Affirmed Overweight at Piper Jaffray on Potential of Arthritis Drug – TheStreet.com

Tuesday, December 3rd, 2019

AbbVie's (ABBV - Get Report) fledgling rheumatoid arthritis treatment Rinvoq is showing promise and appears to be tracking "meaningfully ahead of expectations," according to analysts at Piper Jaffray.

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Study Assesses Risk of Infections, Cancer With Interleukin Inhibitors in Rheumatic Disease – Pharmacy Times

Tuesday, December 3rd, 2019

Study Assesses Risk of Infections, Cancer With Interleukin Inhibitors in Rheumatic Disease According to the study, the risks may be comparable to those reported for other biologics approved for the treatment of rheumatic diseases. A number of IL-1, IL-6, IL-12/23, and IL-17 inhibitors are used as therapy options in rheumatologic diseases. Although IL inhibitors have demonstrated efficacy, there are limited data regarding their safety profile and it is unknown to what extent IL inhibitors may increase the risk of serious infections and cancer.

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Assessment of Aortic Stiffness in Patients With Rheumatoid Arthritis Using Pulse Wave Velocity: An Update Meta-analysis – DocWire News

Tuesday, December 3rd, 2019

BACKGROUNDS: Rheumatoid arthritis (RA) is a systemic autoimmune disease that confers one of the strongest risks for cardiovascular disease (CVD) morbidity and mortality than in general population.

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Comorbidities As Risk Factors for Rheumatoid Arthritis and Their Accrual After Diagnosis – DocWire News

Tuesday, December 3rd, 2019

OBJECTIVE: To determine the prevalence of comorbidities in rheumatoid arthritis (RA), discover which comorbidities might predispose to developing RA, and identify which comorbidities are more likely to develop after RA. We performed a case-control study using a single-center biobank, identifying 821 cases of RA (143 incident RA) between January 1, 2009, and February 28, 2018, defined as 2 diagnosis codes plus a disease-modifying antirheumatic drug

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FDA Action Alert: Celgene, Amgen and Avadel – BioSpace

Tuesday, December 3rd, 2019

As we begin the final month of 2019, the U.S. Food and Drug Administration (FDA) has several PDUFA dates to approve drug applications

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Comparing Perceptions of Psoriatic Arthritis Disease Activity – Physician’s Weekly

Saturday, November 30th, 2019

While guidelines for psoriatic arthritis recommend a treatment target of remission or low disease activity, consensus is lacking on how to define either.

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Expert Insights on Rheumatoid Arthritis From the ACR/ARP 2019 Annual Meeting – Rheumatology Advisor

Saturday, November 30th, 2019

The 2019 annual meeting of the American College of Rheumatology (ACR) had an abundance of sessions dedicated to the management of rheumatoid arthritis (RA).

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Genetics and Weather in NL Producing Highest Incidence of Arthritis in Canada – VOCM

Saturday, November 30th, 2019

Genetics and weather are coming against Newfoundlanders and Labradorians who have the highest incidence of arthritis in Canada. One in four Newfoundlanders and Labradorians suffer from one form of arthritis or another.

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Rheumatoid Arthritis Will Change Your Life. It Doesn’t Have to Ruin It. – HealthCentral.com

Saturday, November 30th, 2019

When I was a little girl, I had high-flying dreams and they had very little to do with my juvenile arthritis, a childhood illness similar to rheumatoid arthritis (RA). First, I wanted to be a ballerina and practiced dance moves on my parents' Persian rug

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