StemCell Therapy

Rates of newly diagnosed cases of type 1 and type 2 diabetes are increasing among children and teens in the United States, according to a report published in theNew England Journal of Medicine (NEJM). The fastest rise is among racial/ethnic minority groups.

As reported in Diabetes Care, in the United States in 2009, an estimated 191,986 youth under age 20 had diabetes; 166,984 had type 1 diabetes, 20,262 had type 2 diabetes, and 4,740 had other types.

Here are four things MCOs should know about the study and why diabetes rates are increasing in young populations.

1. The drivers of increased diabetes are very different for type 1 and type 2 diabetes

The NEJM study is the first one to estimate trends in newly diagnosed cases of diabetes types 1 and 2 in youths from the United States five major racial/ethnic groupsnon-Hispanic whites, non-Hispanic blacks, Hispanics, Asian Americans/Pacific Islanders, and Native Americans. The study included 11,244 youth ages 0 to 19 with type 1 diabetes and 2,846 youth ages 10 to 19 with type 2 diabetes.

The reason for increasing incidences of diabetes is most likely very different for types 1 and 2 diabetes, because they are very different in their etiologies, says Elizabeth J. Mayer-Davis, PhD, the lead author of the study and professor and chair, Department of Nutrition, The University of North Carolina, Chapel Hill, North Carolina. Both involve genetic influences, although the specific genes involved are quite different for the two types, and environmental and behavioral factors are likely very different.

For type 1, the specific environmental or behavioral triggers that push the autoimmune process to destroy cells that produce insulin are unknown. For type 2, its believed that childhood obesitywhich has increasedis the main culprit, Mayer-Davis says.

Giuseppina Imperatore, MD, PhD, a study co-author and epidemiologist at the CDCs Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, adds that several reports have also shown that exposure to maternal diabetes in utero has been associated with increased risk of type 2 diabetes in youth. Other factors, yet to be identified, may also contribute to reduced insulin secretion in youth.

2. Rates of newly diagnosed diabetes are higher for type 2 diabetes

The source of data for the NEJM study, TheSEARCH for Diabetes in Youth studyfunded by the CDC and the National Institutes of Health found that from 2002 to 2012, the rate of newly diagnosed cases of type 1 diabetes in youth increased by about 1.8% each year. During the same period, the rate of newly diagnosed cases of type 2 diabetes increased more quickly, at 4.8%.

As our study has shown, there are differences in risk for both diabetes types 1 and 2 across the various racial and ethnic groups, Imperatore says. Understanding these differences is crucial for identifying factors that lead to these diseases.

More:
Rising diabetes rates in children: Four things health execs should know - ModernMedicine

This entry was posted on May 16, 2017 at 12:46 am and is filed under Diabetes. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed. |