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Archive for the ‘Biotechnology’ Category

Biotechnology Industry Salaries, Bonuses and Benefits …

Thursday, October 27th, 2016

What are some average salaries for jobs in the Biotechnology industry? These pages lists all of the job titles in the Biotechnology industry for which we have salary information. If you know the pay grade of the job you are searching for you can narrow down this list to only view Biotechnology industry jobs that pay less than $30K, $30K-$50K, $50K-$80K, $80K-$100K, or more than $100K. If you are unsure how much your Biotechnology industry job pays you can choose to either browse all Biotechnology industry salaries below or you can search all salaries.

Category: All Accounting Administrative, Support, and Clerical Advertising Aerospace and Defense Agriculture, Forestry, and Fishing Architecture Arts and Entertainment Automotive Aviation and Airlines Banking Biotechnology Clergy Construction and Installation Consulting Services Customer Services Education Energy and Utilities Engineering Entry Level Environment Executive and Management Facilities, Maintenance, and Repair Financial Services Fire, Law Enforcement, and Security Food, Beverage, and Tobacco Government Graphic Arts Healthcare -- Administrative Healthcare -- Nursing Healthcare -- Practitioners Healthcare -- Technicians Hotel, Gaming, Leisure, and Travel Human Resources Insurance Internet and New Media IT -- All IT -- Computers, Hardware IT -- Computers, Software IT -- Executive, Consulting IT -- Manager IT -- Networking Legal Services Library Services Logistics Manufacturing Marketing Materials Management Media -- Broadcast Media -- Print Military Mining Non-Profit and Social Services Personal Care and Service Pharmaceuticals Planning Printing and Publishing Public Relations Purchasing Real Estate Restaurant and Food Services Retail/Wholesale Sales Science and Research Skilled and Trades Sports and Recreation Telecommunications Training Transportation and Warehousing

Industry: Aerospace & Defense Biotechnology Business Services Chemicals Construction Edu., Gov't. & Nonprofit Energy & Utilities Financial Services Healthcare Hospitality & Leisure Insurance Internet Media MFG Durable MFG Nondurable Pharmaceuticals Retail & Wholesale Software & Networking Telecom Transportation

Income Level: All $100,000+ $80,000 - $100,000 $50,000 - $80,000 $30,000 - $50,000 $10,000 - $30,000

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Animal Biotechnology | Bioscience Topics | About Bioscience

Tuesday, October 25th, 2016

Related Links http://www.bbsrc.ac.uk

The Biotechnology and Biological Sciences Research Council (BBSRC) is the United Kingdoms principal funder of basic and strategic biological research. To deliver its mission, the BBSRC supports research and training in universities and research centers and promotes knowledge transfer from research to applications in business, industry and policy, and public engagement in the biosciences. The site contains extensive articles on the ethical and social issues involved in animal biotechnology.

The Department of Agriculture (USDA) provides leadership on food, agriculture, natural resources and related issues through public policy, the best available science and efficient management. The National Institute of Food and Agriculture is part of the USDA; its site contains information about the science behind animal biotechnology and a glossary of terms. Related topics also are searchable, including animal breeding, genetics and many others.

The Pew Initiative on Food and Biotechnology is an independent, objective source of information on agricultural biotechnology. Funded by a grant from the Pew Charitable Trusts to the University of Richmond, it advocates neither for nor against agricultural biotechnology. Instead, the initiative is committed to providing information and encouraging dialogue so consumers and policy-makers can make their own informed decisions.

Animal biotechnology is the use of science and engineering to modify living organisms. The goal is to make products, to improve animals and to develop microorganisms for specific agricultural uses.

Examples of animal biotechnology include creating transgenic animals (animals with one or more genes introduced by human intervention), using gene knock out technology to make animals with a specific inactivated gene and producing nearly identical animals by somatic cell nuclear transfer (or cloning).

The animal biotechnology in use today is built on a long history. Some of the first biotechnology in use includes traditional breeding techniques that date back to 5000 B.C.E. Such techniques include crossing diverse strains of animals (known as hybridizing) to produce greater genetic variety. The offspring from these crosses then are bred selectively to produce the greatest number of desirable traits. For example, female horses have been bred with male donkeys to produce mules, and male horses have been bred with female donkeys to produce hinnies, for use as work animals, for the past 3,000 years. This method continues to be used today.

The modern era of biotechnology began in 1953, when American biochemist James Watson and British biophysicist Francis Crick presented their double-helix model of DNA. That was followed by Swiss microbiologist Werner Arbers discovery in the 1960s of special enzymes, called restriction enzymes, in bacteria. These enzymes cut the DNA strands of any organism at precise points. In 1973, American geneticist Stanley Cohen and American biochemist Herbert Boyer removed a specific gene from one bacterium and inserted it into another using restriction enzymes. That event marked the beginning of recombinant DNA technology, or genetic engineering. In 1977, genes from other organisms were transferred to bacteria, an achievement that led eventually to the first transfer of a human gene.

Animal biotechnology in use today is based on the science of genetic engineering. Under the umbrella of genetic engineering exist other technologies, such as transgenics and cloning, that also are used in animal biotechnology.

Transgenics (also known as recombinant DNA) is the transferal of a specific gene from one organism to another. Gene splicing is used to introduce one or more genes of an organism into a second organism. A transgenic animal is created once the second organism incorporates the new DNA into its own genetic material.

In gene splicing, DNA cannot be transferred directly from its original organism, the donor, to the recipient organism, or the host. Instead, the donor DNA must be cut and pasted, or recombined, into a compatible fragment of DNA from a vector an organism that can carry the donor DNA into the host. The host organism often is a rapidly multiplying microorganism such as a harmless bacterium, which serves as a factory where the recombined DNA can be duplicated in large quantities. The subsequently produced protein then can be removed from the host and used as a genetically engineered product in humans, other animals, plants, bacteria or viruses. The donor DNA can be introduced directly into an organism by techniques such as injection through the cell walls of plants or into the fertilized egg of an animal.

This transferring of genes alters the characteristics of the organism by changing its protein makeup. Proteins, including enzymes and hormones, perform many vital functions in organisms. Individual genes direct an animals characteristics through the production of proteins.

Scientists use reproductive cloning techniques to produce multiple copies of mammals that are nearly identical copies of other animals, including transgenic animals, genetically superior animals and animals that produce high quantities of milk or have some other desirable trait. To date, cattle, sheep, pigs, goats, horses, mules, cats, rats and mice have been cloned, beginning with the first cloned animal, a sheep named Dolly, in 1996.

Reproductive cloning begins with somatic cell nuclear transfer (SCNT). In SCNT, scientists remove the nucleus from an egg cell (oocyte) and replace it with a nucleus from a donor adult somatic cell, which is any cell in the body except for an oocyte or sperm. For reproductive cloning, the embryo is implanted into a uterus of a surrogate female, where it can develop into a live being.

In addition to the use of transgenics and cloning, scientists can use gene knock out technology to inactivate, or knock out, a specific gene. It is this technology that creates a possible source of replacement organs for humans. The process of transplanting cells, tissues or organs from one species to another is referred to as xenotransplantation. Currently, the pig is the major animal being considered as a viable organ donor to humans. Unfortunately, pig cells and human cells are not immunologically compatible. Pigs, like almost all mammals, have markers on their cells that enable the human immune system to recognize them as foreign and reject them. Genetic engineering is used to knock out the pig gene responsible for the protein that forms the marker to the pig cells.

Animal biotechnology has many potential uses. Since the early 1980s, transgenic animals have been created with increased growth rates, enhanced lean muscle mass, enhanced resistance to disease or improved use of dietary phosphorous to lessen the environmental impacts of animal manure. Transgenic poultry, swine, goats and cattle that generate large quantities of human proteins in eggs, milk, blood or urine also have been produced, with the goal of using these products as human pharmaceuticals. Human pharmaceutical proteins include enzymes, clotting factors, albumin and antibodies. The major factor limiting the widespread use of transgenic animals in agricultural production systems is their relatively inefficient production rate (a success rate of less than 10 percent).

A specific example of these particular applications of animal biotechnology is the transfer of the growth hormone gene of rainbow trout directly into carp eggs. The resulting transgenic carp produce both carp and rainbow trout growth hormones and grow to be one-third larger than normal carp. Another example is the use of transgenic animals to clone large quantities of the gene responsible for a cattle growth hormone. The hormone is extracted from the bacterium, is purified and is injected into dairy cows, increasing their milk production by 10 to 15 percent. That growth hormone is called bovine somatotropin or BST.

Another major application of animal biotechnology is the use of animal organs in humans. Pigs currently are used to supply heart valves for insertion into humans, but they also are being considered as a potential solution to the severe shortage in human organs available for transplant procedures.

While predicting the future is inherently risky, some things can be said with certainty about the future of animal biotechnology. The government agencies involved in the regulation of animal biotechnology, mainly the Food and Drug Administration (FDA), likely will rule on pending policies and establish processes for the commercial uses of products created through the technology. In fact, as of March 2006, the FDA was expected to rule in the next few months on whether to approve meat and dairy products from cloned animals for sale to the public. If these animals and animal products are approved for human consumption, several companies reportedly are ready to sell milk, and perhaps meat, from cloned animals most likely cattle and swine. It also is expected that technologies will continue to be developed in the field, with much hope for advances in the use of animal organs in human transplant operations.

The potential benefits of animal biotechnology are numerous and include enhanced nutritional content of food for human consumption; a more abundant, cheaper and varied food supply; agricultural land-use savings; a decrease in the number of animals needed for the food supply; improved health of animals and humans; development of new, low-cost disease treatments for humans; and increased understanding of human disease.

Yet despite these potential benefits, several areas of concern exist around the use of biotechnology in animals. To date, a majority of the American public is uncomfortable with genetic modifications to animals.

According to a survey conducted by the Pew Initiative on Food and Biotechnology, 58 percent of those polled said they opposed scientific research on the genetic engineering of animals. And in a Gallup poll conducted in May 2004, 64 percent of Americans polled said they thought it was morally wrong to clone animals.

Concerns surrounding the use of animal biotechnology include the unknown potential health effects to humans from food products created by transgenic or cloned animals, the potential effects on the environment and the effects on animal welfare.

Before animal biotechnology will be used widely by animal agriculture production systems, additional research will be needed to determine if the benefits of animal biotechnology outweigh these potential risks.

The main question posed about the safety of food produced through animal biotechnology for human consumption is, Is it safe to eat? But answering that question isnt simple. Other questions must be answered first, such as, What substances expressed as a result of the genetic modification are likely to remain in food? Despite these questions, the National Academies of Science (NAS) released a report titled Animal Biotechnology: Science-Based Concerns stating that the overall concern level for food safety was determined to be low. Specifically, the report listed three specific food concerns: allergens, bioactivity and the toxicity of unintended expression products.

The potential for new allergens to be expressed in the process of creating foods from genetically modified animals is a real and valid concern, because the process introduces new proteins. While food allergens are not a new issue, the difficulty comes in how to anticipate these adequately, because they only can be detected once a person is exposed and experiences a reaction.

Another food safety issue, bioactivity, asks, Will putting a functional protein like a growth hormone in an animal affect the person who consumes food from that animal? As of May 2006, scientists cannot say for sure if the proteins will.

Finally, concern exists about the toxicity of unintended expression products in the animal biotechnology process. While the risk is considered low, there is no data available. The NAS report stated it still needs be proven that the nutritional profile does not change in these foods and that no unintended and potentially harmful expression products appear.

Another major concern surrounding the use of animal biotechnology is the potential for negative impact to the environment. These potential harms include the alteration of the ecologic balance regarding feed sources and predators, the introduction of transgenic animals that alter the health of existing animal populations and the disruption of reproduction patterns and their success.

To assess the risk of these environmental harms, many more questions must be answered, such as: What is the possibility the altered animal will enter the environment? Will the animals introduction change the ecological system? Will the animal become established in the environment? and Will it interact with and affect the success of other animals in the new community? Because of the many uncertainties involved, it is challenging to make an assessment.

To illustrate a potential environmental harm, consider that if transgenic salmon with genes engineered to accelerate growth were released into the natural environment, they could compete more successfully for food and mates than wild salmon. Thus, there also is concern that genetically engineered organisms will escape and reproduce in the natural environment. It is feared existing species could be eliminated, thus upsetting the natural balance of organisms.

The regulation of animal biotechnology currently is performed under existing government agencies. To date, no new regulations or laws have been enacted to deal with animal biotechnology and related issues. The main governing body for animal biotechnology and their products is the FDA. Specifically, these products fall under the new animal drug provisions of the Food, Drug, and Cosmetic Act (FDCA). In this use, the introduced genetic construct is considered the drug. This lack of concrete regulatory guidance has produced many questions, especially because the process for bringing genetically engineered animals to market remains unknown.

Currently, the only genetically engineered animal on the market is the GloFish, a transgenic aquarium fish engineered to glow in the dark. It has not been subject to regulation by the FDA, however, because it is not believed to be a threat to the environment.

Many people question the use of an agency that was designed specifically for drugs to regulate live animals. The agencys strict confidentiality provisions and lack of an environmental mandate in the FDCA also are concerns. It still is unclear how the agencys provisions will be interpreted for animals and how multiple agencies will work together in the regulatory system.

When animals are genetically engineered for biomedical research purposes (as pigs are, for example, in organ transplantation studies), their care and use is carefully regulated by the Department of Agriculture. In addition, if federal funds are used to support the research, the work further is regulated by the Public Health Service Policy on Humane Care and Use of Laboratory Animals.

Whether products generated from genetically engineered animals should be labeled is yet another controversy surrounding animal biotechnology. Those opposed to mandatory labeling say it violates the governments traditional focus on regulating products, not processes. If a product of animal biotechnology has been proven scientifically by the FDA to be safe for human consumption and the environment and not materially different from similar products produced via conventional means, these individuals say it is unfair and without scientific rationale to single out that product for labeling solely because of the process by which it was made.

On the other hand, those in favor of mandatory labeling argue labeling is a consumer right-to-know issue. They say consumers need full information about products in the marketplace including the processes used to make those products not for food safety or scientific reasons, but so they can make choices in line with their personal ethics.

On average, it takes seven to nine years and an investment of about $55 million to develop, test and market a new genetically engineered product. Consequently, nearly all researchers involved in animal biotechnology are protecting their investments and intellectual property through the patent system. In 1988, the first patent was issued on a transgenic animal, a strain of laboratory mice whose cells were engineered to contain a cancer-predisposing gene. Some people, however, are opposed ethically to the patenting of life forms, because it makes organisms the property of companies. Other people are concerned about its impact on small farmers. Those opposed to using the patent system for animal biotechnology have suggested using breed registries to protect intellectual property.

Ethical and social considerations surrounding animal biotechnology are of significant importance. This especially is true because researchers and developers worry the future market success of any products derived from cloned or genetically engineered animals will depend partly on the publics acceptance of those products.

Animal biotechnology clearly has its skeptics as well as its outright opponents. Strict opponents think there is something fundamentally immoral about the processes of transgenics and cloning. They liken it to playing God. Moreover, they often oppose animal biotechnology on the grounds that it is unnatural. Its processes, they say, go against nature and, in some cases, cross natural species boundaries.

Still others question the need to genetically engineer animals. Some wonder if it is done so companies can increase profits and agricultural production. They believe a compelling need should exist for the genetic modification of animals and that we should not use animals only for our own wants and needs. And yet others believe it is unethical to stifle technology with the potential to save human lives.

While the field of ethics presents more questions than it answers, it is clear animal biotechnology creates much discussion and debate among scientists, researchers and the American public. Two main areas of debate focus on the welfare of animals involved and the religious issues related to animal biotechnology.

Perhaps the most controversy and debate regarding animal biotechnology surrounds the animals themselves. While it has been noted that animals might, in fact, benefit from the use of animal biotechnology through improved health, for example the majority of discussion is about the known and unknown potential negative impacts to animal welfare through the process.

For example, calves and lambs produced through in vitro fertilization or cloning tend to have higher birth weights and longer gestation periods, which leads to difficult births that often require cesarean sections. In addition, some of the biotechnology techniques in use today are extremely inefficient at producing fetuses that survive. Of the transgenic animals that do survive, many do not express the inserted gene properly, often resulting in anatomical, physiological or behavioral abnormalities. There also is a concern that proteins designed to produce a pharmaceutical product in the animals milk might find their way to other parts of the animals body, possibly causing adverse effects.

Animal telos is a concept derived from Aristotle and refers to an animals fundamental nature. Disagreement exists as to whether it is ethical to change an animals telos through transgenesis. For example, is it ethical to create genetically modified chickens that can tolerate living in small cages? Those opposed to the concept say it is a clear sign we have gone too far in changing that animal.

Those unopposed to changing an animals telos, however, argue it could benefit animals by fitting them for living conditions for which they are not naturally suited. In this way, scientists could create animals that feel no pain.

Religion plays a crucial part in the way some people view animal biotechnology. For some people, these technologies are considered blasphemous. In effect, God has created a perfect, natural order, they say, and it is sinful to try to improve that order by manipulating the basic ingredient of all life, DNA. Some religions place great importance on the integrity of species, and as a result, those religions followers strongly oppose any effort to change animals through genetic modification.

Not all religious believers make these assertions, however, and different believers of the same religion might hold differing views on the subject. For example, Christians do not oppose animal biotechnology unanimously. In fact, some Christians support animal biotechnology, saying the Bible teaches humanitys dominion over nature. Some modern theologians even see biotechnology as a challenging, positive opportunity for us to work with God as co-creators.

Transgenic animals can pose problems for some religious groups. For example, Muslims, Sikhs and Hindus are forbidden to eat certain foods. Such religious requirements raise basic questions about the identity of animals and their genetic makeup. If, for example, a small amount of genetic material from a fish is introduced into a melon (in order to allow it grow to in lower temperatures), does that melon become fishy in any meaningful sense? Some would argue all organisms share common genetic material, so the melon would not contain any of the fishs identity. Others, however, believe the transferred genes are exactly what make the animal distinctive; therefore the melon would be forbidden to be eaten as well.

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Animal Biotechnology | Bioscience Topics | About Bioscience

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History of biotechnology – Wikipedia

Friday, October 21st, 2016

Biotechnology is the application of scientific and engineering principles to the processing of materials by biological agents to provide goods and services.[1] From its inception, biotechnology has maintained a close relationship with society. Although now most often associated with the development of drugs, historically biotechnology has been principally associated with food, addressing such issues as malnutrition and famine. The history of biotechnology begins with zymotechnology, which commenced with a focus on brewing techniques for beer. By World War I, however, zymotechnology would expand to tackle larger industrial issues, and the potential of industrial fermentation gave rise to biotechnology. However, both the single-cell protein and gasohol projects failed to progress due to varying issues including public resistance, a changing economic scene, and shifts in political power.

Yet the formation of a new field, genetic engineering, would soon bring biotechnology to the forefront of science in society, and the intimate relationship between the scientific community, the public, and the government would ensue. These debates gained exposure in 1975 at the Asilomar Conference, where Joshua Lederberg was the most outspoken supporter for this emerging field in biotechnology. By as early as 1978, with the development of synthetic human insulin, Lederberg's claims would prove valid, and the biotechnology industry grew rapidly. Each new scientific advance became a media event designed to capture public support, and by the 1980s, biotechnology grew into a promising real industry. In 1988, only five proteins from genetically engineered cells had been approved as drugs by the United States Food and Drug Administration (FDA), but this number would skyrocket to over 125 by the end of the 1990s.

The field of genetic engineering remains a heated topic of discussion in today's society with the advent of gene therapy, stem cell research, cloning, and genetically modified food. While it seems only natural nowadays to link pharmaceutical drugs as solutions to health and societal problems, this relationship of biotechnology serving social needs began centuries ago.

Biotechnology arose from the field of zymotechnology or zymurgy, which began as a search for a better understanding of industrial fermentation, particularly beer. Beer was an important industrial, and not just social, commodity. In late 19th-century Germany, brewing contributed as much to the gross national product as steel, and taxes on alcohol proved to be significant sources of revenue to the government.[2] In the 1860s, institutes and remunerative consultancies were dedicated to the technology of brewing. The most famous was the private Carlsberg Institute, founded in 1875, which employed Emil Christian Hansen, who pioneered the pure yeast process for the reliable production of consistent beer. Less well known were private consultancies that advised the brewing industry. One of these, the Zymotechnic Institute, was established in Chicago by the German-born chemist John Ewald Siebel.

The heyday and expansion of zymotechnology came in World War I in response to industrial needs to support the war. Max Delbrck grew yeast on an immense scale during the war to meet 60 percent of Germany's animal feed needs.[2] Compounds of another fermentation product, lactic acid, made up for a lack of hydraulic fluid, glycerol. On the Allied side the Russian chemist Chaim Weizmann used starch to eliminate Britain's shortage of acetone, a key raw material for cordite, by fermenting maize to acetone.[3] The industrial potential of fermentation was outgrowing its traditional home in brewing, and "zymotechnology" soon gave way to "biotechnology."

With food shortages spreading and resources fading, some dreamed of a new industrial solution. The Hungarian Kroly Ereky coined the word "biotechnology" in Hungary during 1919 to describe a technology based on converting raw materials into a more useful product. He built a slaughterhouse for a thousand pigs and also a fattening farm with space for 50,000 pigs, raising over 100,000 pigs a year. The enterprise was enormous, becoming one of the largest and most profitable meat and fat operations in the world. In a book entitled Biotechnologie, Ereky further developed a theme that would be reiterated through the 20th century: biotechnology could provide solutions to societal crises, such as food and energy shortages. For Ereky, the term "biotechnologie" indicated the process by which raw materials could be biologically upgraded into socially useful products.[4]

This catchword spread quickly after the First World War, as "biotechnology" entered German dictionaries and was taken up abroad by business-hungry private consultancies as far away as the United States. In Chicago, for example, the coming of prohibition at the end of World War I encouraged biological industries to create opportunities for new fermentation products, in particular a market for nonalcoholic drinks. Emil Siebel, the son of the founder of the Zymotechnic Institute, broke away from his father's company to establish his own called the "Bureau of Biotechnology," which specifically offered expertise in fermented nonalcoholic drinks.[1]

The belief that the needs of an industrial society could be met by fermenting agricultural waste was an important ingredient of the "chemurgic movement."[4] Fermentation-based processes generated products of ever-growing utility. In the 1940s, penicillin was the most dramatic. While it was discovered in England, it was produced industrially in the U.S. using a deep fermentation process originally developed in Peoria, Illinois.[5] The enormous profits and the public expectations penicillin engendered caused a radical shift in the standing of the pharmaceutical industry. Doctors used the phrase "miracle drug", and the historian of its wartime use, David Adams, has suggested that to the public penicillin represented the perfect health that went together with the car and the dream house of wartime American advertising.[2] Beginning in the 1950s, fermentation technology also became advanced enough to produce steroids on industrially significant scales.[6] Of particular importance was the improved semisynthesis of cortisone which simplified the old 31 step synthesis to 11 steps.[7] This advance was estimated to reduce the cost of the drug by 70%, making the medicine inexpensive and available.[8] Today biotechnology still plays a central role in the production of these compounds and likely will for years to come.[9][10]

Even greater expectations of biotechnology were raised during the 1960s by a process that grew single-cell protein. When the so-called protein gap threatened world hunger, producing food locally by growing it from waste seemed to offer a solution. It was the possibilities of growing microorganisms on oil that captured the imagination of scientists, policy makers, and commerce.[1] Major companies such as British Petroleum (BP) staked their futures on it. In 1962, BP built a pilot plant at Cap de Lavera in Southern France to publicize its product, Toprina.[1] Initial research work at Lavera was done by Alfred Champagnat,[11] In 1963, construction started on BP's second pilot plant at Grangemouth Oil Refinery in Britain.[11]

As there was no well-accepted term to describe the new foods, in 1966 the term "single-cell protein" (SCP) was coined at MIT to provide an acceptable and exciting new title, avoiding the unpleasant connotations of microbial or bacterial.[1]

The "food from oil" idea became quite popular by the 1970s, when facilities for growing yeast fed by n-paraffins were built in a number of countries. The Soviets were particularly enthusiastic, opening large "BVK" (belkovo-vitaminny kontsentrat, i.e., "protein-vitamin concentrate") plants next to their oil refineries in Kstovo (1973) [12][13] and Kirishi (1974).[citation needed]

By the late 1970s, however, the cultural climate had completely changed, as the growth in SCP interest had taken place against a shifting economic and cultural scene (136). First, the price of oil rose catastrophically in 1974, so that its cost per barrel was five times greater than it had been two years earlier. Second, despite continuing hunger around the world, anticipated demand also began to shift from humans to animals. The program had begun with the vision of growing food for Third World people, yet the product was instead launched as an animal food for the developed world. The rapidly rising demand for animal feed made that market appear economically more attractive. The ultimate downfall of the SCP project, however, came from public resistance.[1]

This was particularly vocal in Japan, where production came closest to fruition. For all their enthusiasm for innovation and traditional interest in microbiologically produced foods, the Japanese were the first to ban the production of single-cell proteins. The Japanese ultimately were unable to separate the idea of their new "natural" foods from the far from natural connotation of oil.[1] These arguments were made against a background of suspicion of heavy industry in which anxiety over minute traces of petroleum was expressed. Thus, public resistance to an unnatural product led to the end of the SCP project as an attempt to solve world hunger.

Also, in 1989 in the USSR, the public environmental concerns made the government decide to close down (or convert to different technologies) all 8 paraffin-fed-yeast plants that the Soviet Ministry of Microbiological Industry had by that time.[citation needed]

In the late 1970s, biotechnology offered another possible solution to a societal crisis. The escalation in the price of oil in 1974 increased the cost of the Western world's energy tenfold.[1] In response, the U.S. government promoted the production of gasohol, gasoline with 10 percent alcohol added, as an answer to the energy crisis.[2] In 1979, when the Soviet Union sent troops to Afghanistan, the Carter administration cut off its supplies to agricultural produce in retaliation, creating a surplus of agriculture in the U.S. As a result, fermenting the agricultural surpluses to synthesize fuel seemed to be an economical solution to the shortage of oil threatened by the Iran-Iraq war. Before the new direction could be taken, however, the political wind changed again: the Reagan administration came to power in January 1981 and, with the declining oil prices of the 1980s, ended support for the gasohol industry before it was born.[1]

Biotechnology seemed to be the solution for major social problems, including world hunger and energy crises. In the 1960s, radical measures would be needed to meet world starvation, and biotechnology seemed to provide an answer. However, the solutions proved to be too expensive and socially unacceptable, and solving world hunger through SCP food was dismissed. In the 1970s, the food crisis was succeeded by the energy crisis, and here too, biotechnology seemed to provide an answer. But once again, costs proved prohibitive as oil prices slumped in the 1980s. Thus, in practice, the implications of biotechnology were not fully realized in these situations. But this would soon change with the rise of genetic engineering.

The origins of biotechnology culminated with the birth of genetic engineering. There were two key events that have come to be seen as scientific breakthroughs beginning the era that would unite genetics with biotechnology. One was the 1953 discovery of the structure of DNA, by Watson and Crick, and the other was the 1973 discovery by Cohen and Boyer of a recombinant DNA technique by which a section of DNA was cut from the plasmid of an E. coli bacterium and transferred into the DNA of another.[14] This approach could, in principle, enable bacteria to adopt the genes and produce proteins of other organisms, including humans. Popularly referred to as "genetic engineering," it came to be defined as the basis of new biotechnology.

Genetic engineering proved to be a topic that thrust biotechnology into the public scene, and the interaction between scientists, politicians, and the public defined the work that was accomplished in this area. Technical developments during this time were revolutionary and at times frightening. In December 1967, the first heart transplant by Christian Barnard reminded the public that the physical identity of a person was becoming increasingly problematic. While poetic imagination had always seen the heart at the center of the soul, now there was the prospect of individuals being defined by other people's hearts.[1] During the same month, Arthur Kornberg announced that he had managed to biochemically replicate a viral gene. "Life had been synthesized," said the head of the National Institutes of Health.[1] Genetic engineering was now on the scientific agenda, as it was becoming possible to identify genetic characteristics with diseases such as beta thalassemia and sickle-cell anemia.

Responses to scientific achievements were colored by cultural skepticism. Scientists and their expertise were looked upon with suspicion. In 1968, an immensely popular work, The Biological Time Bomb, was written by the British journalist Gordon Rattray Taylor. The author's preface saw Kornberg's discovery of replicating a viral gene as a route to lethal doomsday bugs. The publisher's blurb for the book warned that within ten years, "You may marry a semi-artificial man or womanchoose your children's sextune out painchange your memoriesand live to be 150 if the scientific revolution doesnt destroy us first."[1] The book ended with a chapter called "The Future If Any." While it is rare for current science to be represented in the movies, in this period of "Star Trek", science fiction and science fact seemed to be converging. "Cloning" became a popular word in the media. Woody Allen satirized the cloning of a person from a nose in his 1973 movie Sleeper, and cloning Adolf Hitler from surviving cells was the theme of the 1976 novel by Ira Levin, The Boys from Brazil.[1]

In response to these public concerns, scientists, industry, and governments increasingly linked the power of recombinant DNA to the immensely practical functions that biotechnology promised. One of the key scientific figures that attempted to highlight the promising aspects of genetic engineering was Joshua Lederberg, a Stanford professor and Nobel laureate. While in the 1960s "genetic engineering" described eugenics and work involving the manipulation of the human genome, Lederberg stressed research that would involve microbes instead.[1] Lederberg emphasized the importance of focusing on curing living people. Lederberg's 1963 paper, "Biological Future of Man" suggested that, while molecular biology might one day make it possible to change the human genotype, "what we have overlooked is euphenics, the engineering of human development."[1] Lederberg constructed the word "euphenics" to emphasize changing the phenotype after conception rather than the genotype which would affect future generations.

With the discovery of recombinant DNA by Cohen and Boyer in 1973, the idea that genetic engineering would have major human and societal consequences was born. In July 1974, a group of eminent molecular biologists headed by Paul Berg wrote to Science suggesting that the consequences of this work were so potentially destructive that there should be a pause until its implications had been thought through.[1] This suggestion was explored at a meeting in February 1975 at California's Monterey Peninsula, forever immortalized by the location, Asilomar. Its historic outcome was an unprecedented call for a halt in research until it could be regulated in such a way that the public need not be anxious, and it led to a 16-month moratorium until National Institutes of Health (NIH) guidelines were established.

Joshua Lederberg was the leading exception in emphasizing, as he had for years, the potential benefits. At Asilomar, in an atmosphere favoring control and regulation, he circulated a paper countering the pessimism and fears of misuses with the benefits conferred by successful use. He described "an early chance for a technology of untold importance for diagnostic and therapeutic medicine: the ready production of an unlimited variety of human proteins. Analogous applications may be foreseen in fermentation process for cheaply manufacturing essential nutrients, and in the improvement of microbes for the production of antibiotics and of special industrial chemicals."[1] In June 1976, the 16-month moratorium on research expired with the Director's Advisory Committee (DAC) publication of the NIH guidelines of good practice. They defined the risks of certain kinds of experiments and the appropriate physical conditions for their pursuit, as well as a list of things too dangerous to perform at all. Moreover, modified organisms were not to be tested outside the confines of a laboratory or allowed into the environment.[14]

Atypical as Lederberg was at Asilomar, his optimistic vision of genetic engineering would soon lead to the development of the biotechnology industry. Over the next two years, as public concern over the dangers of recombinant DNA research grew, so too did interest in its technical and practical applications. Curing genetic diseases remained in the realms of science fiction, but it appeared that producing human simple proteins could be good business. Insulin, one of the smaller, best characterized and understood proteins, had been used in treating type 1 diabetes for a half century. It had been extracted from animals in a chemically slightly different form from the human product. Yet, if one could produce synthetic human insulin, one could meet an existing demand with a product whose approval would be relatively easy to obtain from regulators. In the period 1975 to 1977, synthetic "human" insulin represented the aspirations for new products that could be made with the new biotechnology. Microbial production of synthetic human insulin was finally announced in September 1978 and was produced by a startup company, Genentech.[15] Although that company did not commercialize the product themselves, instead, it licensed the production method to Eli Lilly and Company. 1978 also saw the first application for a patent on a gene, the gene which produces human growth hormone, by the University of California, thus introducing the legal principle that genes could be patented. Since that filing, almost 20% of the more than 20,000 genes in the human DNA have been patented.[citation needed]

The radical shift in the connotation of "genetic engineering" from an emphasis on the inherited characteristics of people to the commercial production of proteins and therapeutic drugs was nurtured by Joshua Lederberg. His broad concerns since the 1960s had been stimulated by enthusiasm for science and its potential medical benefits. Countering calls for strict regulation, he expressed a vision of potential utility. Against a belief that new techniques would entail unmentionable and uncontrollable consequences for humanity and the environment, a growing consensus on the economic value of recombinant DNA emerged.[citation needed]

With ancestral roots in industrial microbiology that date back centuries, the new biotechnology industry grew rapidly beginning in the mid-1970s. Each new scientific advance became a media event designed to capture investment confidence and public support.[15] Although market expectations and social benefits of new products were frequently overstated, many people were prepared to see genetic engineering as the next great advance in technological progress. By the 1980s, biotechnology characterized a nascent real industry, providing titles for emerging trade organizations such as the Biotechnology Industry Organization (BIO).

The main focus of attention after insulin were the potential profit makers in the pharmaceutical industry: human growth hormone and what promised to be a miraculous cure for viral diseases, interferon. Cancer was a central target in the 1970s because increasingly the disease was linked to viruses.[14] By 1980, a new company, Biogen, had produced interferon through recombinant DNA. The emergence of interferon and the possibility of curing cancer raised money in the community for research and increased the enthusiasm of an otherwise uncertain and tentative society. Moreover, to the 1970s plight of cancer was added AIDS in the 1980s, offering an enormous potential market for a successful therapy, and more immediately, a market for diagnostic tests based on monoclonal antibodies.[16] By 1988, only five proteins from genetically engineered cells had been approved as drugs by the United States Food and Drug Administration (FDA): synthetic insulin, human growth hormone, hepatitis B vaccine, alpha-interferon, and tissue plasminogen activator (TPa), for lysis of blood clots. By the end of the 1990s, however, 125 more genetically engineered drugs would be approved.[16]

Genetic engineering also reached the agricultural front as well. There was tremendous progress since the market introduction of the genetically engineered Flavr Savr tomato in 1994.[16] Ernst and Young reported that in 1998, 30% of the U.S. soybean crop was expected to be from genetically engineered seeds. In 1998, about 30% of the US cotton and corn crops were also expected to be products of genetic engineering.[16]

Genetic engineering in biotechnology stimulated hopes for both therapeutic proteins, drugs and biological organisms themselves, such as seeds, pesticides, engineered yeasts, and modified human cells for treating genetic diseases. From the perspective of its commercial promoters, scientific breakthroughs, industrial commitment, and official support were finally coming together, and biotechnology became a normal part of business. No longer were the proponents for the economic and technological significance of biotechnology the iconoclasts.[1] Their message had finally become accepted and incorporated into the policies of governments and industry.

According to Burrill and Company, an industry investment bank, over $350 billion has been invested in biotech since the emergence of the industry, and global revenues rose from $23 billion in 2000 to more than $50 billion in 2005. The greatest growth has been in Latin America but all regions of the world have shown strong growth trends. By 2007 and into 2008, though, a downturn in the fortunes of biotech emerged, at least in the United Kingdom, as the result of declining investment in the face of failure of biotech pipelines to deliver and a consequent downturn in return on investment.[17]

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Biotechnology – Wikipedia

Thursday, October 20th, 2016

"Bioscience" redirects here. For the scientific journal, see BioScience. For life sciences generally, see life science.

Biotechnology is the use of living systems and organisms to develop or make products, or "any technological application that uses biological systems, living organisms or derivatives thereof, to make or modify products or processes for specific use" (UN Convention on Biological Diversity, Art. 2).[1] Depending on the tools and applications, it often overlaps with the (related) fields of bioengineering, biomedical engineering, biomanufacturing, molecular engineering, etc.

For thousands of years, humankind has used biotechnology in agriculture, food production, and medicine.[2] The term is largely believed to have been coined in 1919 by Hungarian engineer Kroly Ereky. In the late 20th and early 21st century, biotechnology has expanded to include new and diverse sciences such as genomics, recombinant gene techniques, applied immunology, and development of pharmaceutical therapies and diagnostic tests.[2]

The wide concept of "biotech" or "biotechnology" encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials and organisms such as pharmaceuticals, crops, and livestock.[3] As per European Federation of Biotechnology, Biotechnology is the integration of natural science and organisms, cells, parts thereof, and molecular analogues for products and services.[4] Biotechnology also writes on the pure biological sciences (animal cell culture, biochemistry, cell biology, embryology, genetics, microbiology, and molecular biology). In many instances, it is also dependent on knowledge and methods from outside the sphere of biology including:

Conversely, modern biological sciences (including even concepts such as molecular ecology) are intimately entwined and heavily dependent on the methods developed through biotechnology and what is commonly thought of as the life sciences industry. Biotechnology is the research and development in the laboratory using bioinformatics for exploration, extraction, exploitation and production from any living organisms and any source of biomass by means of biochemical engineering where high value-added products could be planned (reproduced by biosynthesis, for example), forecasted, formulated, developed, manufactured and marketed for the purpose of sustainable operations (for the return from bottomless initial investment on R & D) and gaining durable patents rights (for exclusives rights for sales, and prior to this to receive national and international approval from the results on animal experiment and human experiment, especially on the pharmaceutical branch of biotechnology to prevent any undetected side-effects or safety concerns by using the products).[5][6][7]

By contrast, bioengineering is generally thought of as a related field that more heavily emphasizes higher systems approaches (not necessarily the altering or using of biological materials directly) for interfacing with and utilizing living things. Bioengineering is the application of the principles of engineering and natural sciences to tissues, cells and molecules. This can be considered as the use of knowledge from working with and manipulating biology to achieve a result that can improve functions in plants and animals.[8] Relatedly, biomedical engineering is an overlapping field that often draws upon and applies biotechnology (by various definitions), especially in certain sub-fields of biomedical and/or chemical engineering such as tissue engineering, biopharmaceutical engineering, and genetic engineering.

Although not normally what first comes to mind, many forms of human-derived agriculture clearly fit the broad definition of "'utilizing a biotechnological system to make products". Indeed, the cultivation of plants may be viewed as the earliest biotechnological enterprise.

Agriculture has been theorized to have become the dominant way of producing food since the Neolithic Revolution. Through early biotechnology, the earliest farmers selected and bred the best suited crops, having the highest yields, to produce enough food to support a growing population. As crops and fields became increasingly large and difficult to maintain, it was discovered that specific organisms and their by-products could effectively fertilize, restore nitrogen, and control pests. Throughout the history of agriculture, farmers have inadvertently altered the genetics of their crops through introducing them to new environments and breeding them with other plants one of the first forms of biotechnology.

These processes also were included in early fermentation of beer.[9] These processes were introduced in early Mesopotamia, Egypt, China and India, and still use the same basic biological methods. In brewing, malted grains (containing enzymes) convert starch from grains into sugar and then adding specific yeasts to produce beer. In this process, carbohydrates in the grains were broken down into alcohols such as ethanol. Later other cultures produced the process of lactic acid fermentation which allowed the fermentation and preservation of other forms of food, such as soy sauce. Fermentation was also used in this time period to produce leavened bread. Although the process of fermentation was not fully understood until Louis Pasteur's work in 1857, it is still the first use of biotechnology to convert a food source into another form.

Before the time of Charles Darwin's work and life, animal and plant scientists had already used selective breeding. Darwin added to that body of work with his scientific observations about the ability of science to change species. These accounts contributed to Darwin's theory of natural selection.[10]

For thousands of years, humans have used selective breeding to improve production of crops and livestock to use them for food. In selective breeding, organisms with desirable characteristics are mated to produce offspring with the same characteristics. For example, this technique was used with corn to produce the largest and sweetest crops.[11]

In the early twentieth century scientists gained a greater understanding of microbiology and explored ways of manufacturing specific products. In 1917, Chaim Weizmann first used a pure microbiological culture in an industrial process, that of manufacturing corn starch using Clostridium acetobutylicum, to produce acetone, which the United Kingdom desperately needed to manufacture explosives during World War I.[12]

Biotechnology has also led to the development of antibiotics. In 1928, Alexander Fleming discovered the mold Penicillium. His work led to the purification of the antibiotic compound formed by the mold by Howard Florey, Ernst Boris Chain and Norman Heatley to form what we today know as penicillin. In 1940, penicillin became available for medicinal use to treat bacterial infections in humans.[11]

The field of modern biotechnology is generally thought of as having been born in 1971 when Paul Berg's (Stanford) experiments in gene splicing had early success. Herbert W. Boyer (Univ. Calif. at San Francisco) and Stanley N. Cohen (Stanford) significantly advanced the new technology in 1972 by transferring genetic material into a bacterium, such that the imported material would be reproduced. The commercial viability of a biotechnology industry was significantly expanded on June 16, 1980, when the United States Supreme Court ruled that a genetically modified microorganism could be patented in the case of Diamond v. Chakrabarty.[13] Indian-born Ananda Chakrabarty, working for General Electric, had modified a bacterium (of the Pseudomonas genus) capable of breaking down crude oil, which he proposed to use in treating oil spills. (Chakrabarty's work did not involve gene manipulation but rather the transfer of entire organelles between strains of the Pseudomonas bacterium.

Revenue in the industry is expected to grow by 12.9% in 2008. Another factor influencing the biotechnology sector's success is improved intellectual property rights legislationand enforcementworldwide, as well as strengthened demand for medical and pharmaceutical products to cope with an ageing, and ailing, U.S. population.[14]

Rising demand for biofuels is expected to be good news for the biotechnology sector, with the Department of Energy estimating ethanol usage could reduce U.S. petroleum-derived fuel consumption by up to 30% by 2030. The biotechnology sector has allowed the U.S. farming industry to rapidly increase its supply of corn and soybeansthe main inputs into biofuelsby developing genetically modified seeds which are resistant to pests and drought. By boosting farm productivity, biotechnology plays a crucial role in ensuring that biofuel production targets are met.[15]

Biotechnology has applications in four major industrial areas, including health care (medical), crop production and agriculture, non food (industrial) uses of crops and other products (e.g. biodegradable plastics, vegetable oil, biofuels), and environmental uses.

For example, one application of biotechnology is the directed use of organisms for the manufacture of organic products (examples include beer and milk products). Another example is using naturally present bacteria by the mining industry in bioleaching. Biotechnology is also used to recycle, treat waste, clean up sites contaminated by industrial activities (bioremediation), and also to produce biological weapons.

A series of derived terms have been coined to identify several branches of biotechnology; for example:

The investment and economic output of all of these types of applied biotechnologies is termed as "bioeconomy".

In medicine, modern biotechnology finds applications in areas such as pharmaceutical drug discovery and production, pharmacogenomics, and genetic testing (or genetic screening).

Pharmacogenomics (a combination of pharmacology and genomics) is the technology that analyses how genetic makeup affects an individual's response to drugs.[17] It deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity.[18] By doing so, pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects.[19] Such approaches promise the advent of "personalized medicine"; in which drugs and drug combinations are optimized for each individual's unique genetic makeup.[20][21]

Biotechnology has contributed to the discovery and manufacturing of traditional small molecule pharmaceutical drugs as well as drugs that are the product of biotechnology biopharmaceutics. Modern biotechnology can be used to manufacture existing medicines relatively easily and cheaply. The first genetically engineered products were medicines designed to treat human diseases. To cite one example, in 1978 Genentech developed synthetic humanized insulin by joining its gene with a plasmid vector inserted into the bacterium Escherichia coli. Insulin, widely used for the treatment of diabetes, was previously extracted from the pancreas of abattoir animals (cattle and/or pigs). The resulting genetically engineered bacterium enabled the production of vast quantities of synthetic human insulin at relatively low cost.[22][23] Biotechnology has also enabled emerging therapeutics like gene therapy. The application of biotechnology to basic science (for example through the Human Genome Project) has also dramatically improved our understanding of biology and as our scientific knowledge of normal and disease biology has increased, our ability to develop new medicines to treat previously untreatable diseases has increased as well.[23]

Genetic testing allows the genetic diagnosis of vulnerabilities to inherited diseases, and can also be used to determine a child's parentage (genetic mother and father) or in general a person's ancestry. In addition to studying chromosomes to the level of individual genes, genetic testing in a broader sense includes biochemical tests for the possible presence of genetic diseases, or mutant forms of genes associated with increased risk of developing genetic disorders. Genetic testing identifies changes in chromosomes, genes, or proteins.[24] Most of the time, testing is used to find changes that are associated with inherited disorders. The results of a genetic test can confirm or rule out a suspected genetic condition or help determine a person's chance of developing or passing on a genetic disorder. As of 2011 several hundred genetic tests were in use.[25][26] Since genetic testing may open up ethical or psychological problems, genetic testing is often accompanied by genetic counseling.

Genetically modified crops ("GM crops", or "biotech crops") are plants used in agriculture, the DNA of which has been modified with genetic engineering techniques. In most cases the aim is to introduce a new trait to the plant which does not occur naturally in the species.

Examples in food crops include resistance to certain pests,[27] diseases,[28] stressful environmental conditions,[29] resistance to chemical treatments (e.g. resistance to a herbicide[30]), reduction of spoilage,[31] or improving the nutrient profile of the crop.[32] Examples in non-food crops include production of pharmaceutical agents,[33]biofuels,[34] and other industrially useful goods,[35] as well as for bioremediation.[36][37]

Farmers have widely adopted GM technology. Between 1996 and 2011, the total surface area of land cultivated with GM crops had increased by a factor of 94, from 17,000 square kilometers (4,200,000 acres) to 1,600,000km2 (395 million acres).[38] 10% of the world's crop lands were planted with GM crops in 2010.[38] As of 2011, 11 different transgenic crops were grown commercially on 395 million acres (160 million hectares) in 29 countries such as the USA, Brazil, Argentina, India, Canada, China, Paraguay, Pakistan, South Africa, Uruguay, Bolivia, Australia, Philippines, Myanmar, Burkina Faso, Mexico and Spain.[38]

Genetically modified foods are foods produced from organisms that have had specific changes introduced into their DNA with the methods of genetic engineering. These techniques have allowed for the introduction of new crop traits as well as a far greater control over a food's genetic structure than previously afforded by methods such as selective breeding and mutation breeding.[39] Commercial sale of genetically modified foods began in 1994, when Calgene first marketed its Flavr Savr delayed ripening tomato.[40] To date most genetic modification of foods have primarily focused on cash crops in high demand by farmers such as soybean, corn, canola, and cotton seed oil. These have been engineered for resistance to pathogens and herbicides and better nutrient profiles. GM livestock have also been experimentally developed, although as of November 2013 none are currently on the market.[41]

There is a scientific consensus[42][43][44][45] that currently available food derived from GM crops poses no greater risk to human health than conventional food,[46][47][48][49][50] but that each GM food needs to be tested on a case-by-case basis before introduction.[51][52][53] Nonetheless, members of the public are much less likely than scientists to perceive GM foods as safe.[54][55][56][57] The legal and regulatory status of GM foods varies by country, with some nations banning or restricting them, and others permitting them with widely differing degrees of regulation.[58][59][60][61]

GM crops also provide a number of ecological benefits, if not used in excess.[62] However, opponents have objected to GM crops per se on several grounds, including environmental concerns, whether food produced from GM crops is safe, whether GM crops are needed to address the world's food needs, and economic concerns raised by the fact these organisms are subject to intellectual property law.

Industrial biotechnology (known mainly in Europe as white biotechnology) is the application of biotechnology for industrial purposes, including industrial fermentation. It includes the practice of using cells such as micro-organisms, or components of cells like enzymes, to generate industrially useful products in sectors such as chemicals, food and feed, detergents, paper and pulp, textiles and biofuels.[63] In doing so, biotechnology uses renewable raw materials and may contribute to lowering greenhouse gas emissions and moving away from a petrochemical-based economy.[64]

The environment can be affected by biotechnologies, both positively and adversely. Vallero and others have argued that the difference between beneficial biotechnology (e.g. bioremediation to clean up an oil spill or hazard chemical leak) versus the adverse effects stemming from biotechnological enterprises (e.g. flow of genetic material from transgenic organisms into wild strains) can be seen as applications and implications, respectively.[65] Cleaning up environmental wastes is an example of an application of environmental biotechnology; whereas loss of biodiversity or loss of containment of a harmful microbe are examples of environmental implications of biotechnology.

The regulation of genetic engineering concerns approaches taken by governments to assess and manage the risks associated with the use of genetic engineering technology, and the development and release of genetically modified organisms (GMO), including genetically modified crops and genetically modified fish. There are differences in the regulation of GMOs between countries, with some of the most marked differences occurring between the USA and Europe.[66] Regulation varies in a given country depending on the intended use of the products of the genetic engineering. For example, a crop not intended for food use is generally not reviewed by authorities responsible for food safety.[67] The European Union differentiates between approval for cultivation within the EU and approval for import and processing. While only a few GMOs have been approved for cultivation in the EU a number of GMOs have been approved for import and processing.[68] The cultivation of GMOs has triggered a debate about coexistence of GM and non GM crops. Depending on the coexistence regulations incentives for cultivation of GM crops differ.[69]

In 1988, after prompting from the United States Congress, the National Institute of General Medical Sciences (National Institutes of Health) (NIGMS) instituted a funding mechanism for biotechnology training. Universities nationwide compete for these funds to establish Biotechnology Training Programs (BTPs). Each successful application is generally funded for five years then must be competitively renewed. Graduate students in turn compete for acceptance into a BTP; if accepted, then stipend, tuition and health insurance support is provided for two or three years during the course of their Ph.D. thesis work. Nineteen institutions offer NIGMS supported BTPs.[70] Biotechnology training is also offered at the undergraduate level and in community colleges.

The literature about Biodiversity and the GE food/feed consumption has sometimes resulted in animated debate regarding the suitability of the experimental designs, the choice of the statistical methods or the public accessibility of data. Such debate, even if positive and part of the natural process of review by the scientific community, has frequently been distorted by the media and often used politically and inappropriately in anti-GE crops campaigns.

Domingo, Jos L.; Bordonaba, Jordi Gin (2011). "A literature review on the safety assessment of genetically modified plants" (PDF). Environment International. 37: 734742. doi:10.1016/j.envint.2011.01.003. In spite of this, the number of studies specifically focused on safety assessment of GM plants is still limited. However, it is important to remark that for the first time, a certain equilibrium in the number of research groups suggesting, on the basis of their studies, that a number of varieties of GM products (mainly maize and soybeans) are as safe and nutritious as the respective conventional non-GM plant, and those raising still serious concerns, was observed. Moreover, it is worth mentioning that most of the studies demonstrating that GM foods are as nutritional and safe as those obtained by conventional breeding, have been performed by biotechnology companies or associates, which are also responsible of commercializing these GM plants. Anyhow, this represents a notable advance in comparison with the lack of studies published in recent years in scientific journals by those companies.

Krimsky, Sheldon (2015). "An Illusory Consensus behind GMO Health Assessment" (PDF). Science, Technology, & Human Values: 132. doi:10.1177/0162243915598381. I began this article with the testimonials from respected scientists that there is literally no scientific controversy over the health effects of GMOs. My investigation into the scientific literature tells another story.

And contrast:

Panchin, Alexander Y.; Tuzhikov, Alexander I. (January 14, 2016). "Published GMO studies find no evidence of harm when corrected for multiple comparisons". Critical Reviews in Biotechnology. doi:10.3109/07388551.2015.1130684. ISSN0738-8551. Here, we show that a number of articles some of which have strongly and negatively influenced the public opinion on GM crops and even provoked political actions, such as GMO embargo, share common flaws in the statistical evaluation of the data. Having accounted for these flaws, we conclude that the data presented in these articles does not provide any substantial evidence of GMO harm.

The presented articles suggesting possible harm of GMOs received high public attention. However, despite their claims, they actually weaken the evidence for the harm and lack of substantial equivalency of studied GMOs. We emphasize that with over 1783 published articles on GMOs over the last 10 years it is expected that some of them should have reported undesired differences between GMOs and conventional crops even if no such differences exist in reality.

and

Yang, Y.T.; Chen, B. (2016). "Governing GMOs in the USA: science, law and public health". Journal of the Science of Food and Agriculture. 96: 18511855. doi:10.1002/jsfa.7523. It is therefore not surprising that efforts to require labeling and to ban GMOs have been a growing political issue in the USA (citing Domingo and Bordonaba, 2011).

Overall, a broad scientific consensus holds that currently marketed GM food poses no greater risk than conventional food... Major national and international science and medical associations have stated that no adverse human health effects related to GMO food have been reported or substantiated in peer-reviewed literature to date.

Despite various concerns, today, the American Association for the Advancement of Science, the World Health Organization, and many independent international science organizations agree that GMOs are just as safe as other foods. Compared with conventional breeding techniques, genetic engineering is far more precise and, in most cases, less likely to create an unexpected outcome.

Pinholster, Ginger (October 25, 2012). "AAAS Board of Directors: Legally Mandating GM Food Labels Could "Mislead and Falsely Alarm Consumers"". American Association for the Advancement of Science. Retrieved February 8, 2016.

"REPORT 2 OF THE COUNCIL ON SCIENCE AND PUBLIC HEALTH (A-12): Labeling of Bioengineered Foods" (PDF). American Medical Association. 2012. Retrieved March 19, 2016. Bioengineered foods have been consumed for close to 20 years, and during that time, no overt consequences on human health have been reported and/or substantiated in the peer-reviewed literature.

GM foods currently available on the international market have passed safety assessments and are not likely to present risks for human health. In addition, no effects on human health have been shown as a result of the consumption of such foods by the general population in the countries where they have been approved. Continuous application of safety assessments based on the Codex Alimentarius principles and, where appropriate, adequate post market monitoring, should form the basis for ensuring the safety of GM foods.

"Genetically modified foods and health: a second interim statement" (PDF). British Medical Association. March 2004. Retrieved March 21, 2016. In our view, the potential for GM foods to cause harmful health effects is very small and many of the concerns expressed apply with equal vigour to conventionally derived foods. However, safety concerns cannot, as yet, be dismissed completely on the basis of information currently available.

When seeking to optimise the balance between benefits and risks, it is prudent to err on the side of caution and, above all, learn from accumulating knowledge and experience. Any new technology such as genetic modification must be examined for possible benefits and risks to human health and the environment. As with all novel foods, safety assessments in relation to GM foods must be made on a case-by-case basis.

Members of the GM jury project were briefed on various aspects of genetic modification by a diverse group of acknowledged experts in the relevant subjects. The GM jury reached the conclusion that the sale of GM foods currently available should be halted and the moratorium on commercial growth of GM crops should be continued. These conclusions were based on the precautionary principle and lack of evidence of any benefit. The Jury expressed concern over the impact of GM crops on farming, the environment, food safety and other potential health effects.

The Royal Society review (2002) concluded that the risks to human health associated with the use of specific viral DNA sequences in GM plants are negligible, and while calling for caution in the introduction of potential allergens into food crops, stressed the absence of evidence that commercially available GM foods cause clinical allergic manifestations. The BMA shares the view that that there is no robust evidence to prove that GM foods are unsafe but we endorse the call for further research and surveillance to provide convincing evidence of safety and benefit.

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High Growth Industry Profile – Biotechnology

Friday, September 23rd, 2016

Recruitment and Retention

To succeed and grow in the 21st century economy, biotechnology employers need to fill each position in their companies - from entry-level to the most advanced - with qualified and skilled individuals. Because the industry is experiencing such rapid growth, biotechnology firms often demand more skilled workers than are available and are projected to need more workers than are currently enrolled in training programs.

Skills Competencies and Training

While there may be instances where locally industry-driven career ladders and competency models exist, there is a challenge with the lack of nationally-recognized articulated skills competencies and career ladders as well as sources of training. However, the biotechnology industry's challenges in this area are complicated by the rapidly changing environment in which the industry operates. Advances in the underlying sciences have a continuous effect on the technology and processes used by the biotechnology industry; making it necessary for employees working in the industry to upgrade their skills to maintain productivity.

Image and Outreach to the Public

There is a need for clear information about career options within the biotechnology industry geared towards youth, educators and job seekers for career exploration and recruitment activities. Currently this lack of available information results in a disconnect between these groups and presents a challenge for the industry because the lack of definition and outreach limits the number of people who consider the biotechnology field to be a viable career option.

(Source: U.S. Department of Commerce, Survey of the Use of Biotechnology in U.S. Industry and U.S. Bureau of Labor Statistics, 2006-07 Career Guide to Industries)

In June 2003, ETA announced the High Growth Job Training Initiative to engage businesses with local education providers and the local/regional workforce investment system to find solutions that address changing talent development needs in various industries.

In October 2005, the Community-Based Job Training Grants were announced to improve the role of community colleges in providing affordable, flexible and accessible education for the nation's workforce.

ETA is investing more than $260 million in 26 different regions across the United States in support of the WIRED (Workforce Innovation in Regional Economic Development) Initiative. Through WIRED, local leaders design and implement strategic approaches to regional economic development and job growth. WIRED focuses on catalyzing the creation of high skill, high wage opportunities for American workers through an integrated approach to economic and talent development.

These initiatives reinforce ETA's commitment to transform the workforce system through engaging business, education, state and local governments and other federal agencies with the goal of creating a skilled workforce to meet the dynamic needs of today's economy.

ETA has invested $33,985,520 in the biotechnology industry. This includes 16 High Growth Job Training Initiative grants totaling $22,921,599 and seven Community-Based Job Training Grants totaling $11,063,921. Leveraged resources from all of the grantees total $23,847,037.

For additional background information about the industry and details on the grants, information about employment and training opportunities and workforce development tools for employers, educators and workforce professionals, please visit: http://www.doleta.gov/business/, http://www.careeronestop.org, and http://www.workforce3one.org.

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High Growth Industry Profile - Biotechnology

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BIOtechNow

Friday, September 9th, 2016

BIO is undertaking an aggressive effort to promote the value of biopharmaceutical innovations and ensure that all patients have access to the drugs they need. A vital component of this campaign is holding insurers and their allies accountable for standing in the way of that access. For months, weve blown the whistle on their discriminatory practices, high cost-sharing and cost-shifting, and their blatant falsehoods on whats driving their premium increases, and today, were introducing a ReadMore>

Last week, the Washington Post published an article titled Alzheimers Drug Trial Sparks Optimism which highlighted new findings from a paper published in Nature. They shared exciting news of positive early trial results for a potential new Alzheimers treatment. Overall this is the best news that weve had in my 25 years doing Alzheimers clinical research and it brings new hope for patients and families most affected by the disease, said one of the studys ReadMore>

Before innovative therapies can start helping patients, successful matches between investors and entrepreneurs seeking to develop new medicines must occur. Without access to capital, potentially lifesaving drugs will exist only as ideas. Every fall investors looking for good prospects in the biotech sector gather at the BIO Investor Forum in San Franciscothe birthplace of biotechnology and home to over 1,600 life sciences companies. Many of these companies and others from around the country come to ReadMore>

Casey Whitaker, Communications Coordinator, Animal Agriculture Alliance | 09/08/2016

I have always been a perfectionist when it comes to my work, so its no surprise I found my passion in an industry that also strives for perfection. Animal agriculture never stops reaching for the highest quality of animal care, environmental stewardship and food safety possible. The industry strives for perfection, but also knows that perfection is hard to come by in agriculture because farmers, ranchers, veterinarians and all those involved in the farm-to-fork process ReadMore>

Hans Sauer, Deputy General Counsel, Intellectual Property, Legal, BIO | 09/07/2016

The topic of inter partes reviews (IPRs) has dominated conversation in patent circles for the last several years (see our archive for some of our past articles on the subject). As uncertainty grows in the biopharma community about IPR procedures and the future of innovation, BIO will make IPRs a major topic of discussion at our upcoming IP and Diagnostics Symposium (BIO IPDX) as well as BIOs IP Counsels Committee Meeting in November. An administrative ReadMore>

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FBIOX – Fidelity Select Biotechnology Portfolio | Fidelity …

Friday, September 9th, 2016

Objective

Seeks capital appreciation.

Investing primarily in companies engaged in the research, development, manufacture, and distribution of various biotechnological products, services, and processes and companies that benefit significantly from scientific and technological advances in biotechnology. Normally investing at least 80% of assets in securities of companies principally engaged in these activities. Normally investing primarily in common stocks.

Stock markets, especially foreign markets, are volatile and can decline significantly in response to adverse issuer, political, regulatory, market, or economic developments. Foreign securities are subject to interest rate, currency exchange rate, economic, and political risks. Focus funds can be more volatile because of their narrow concentration in a specific industry. The biotechnology industry can be significantly affected by patent considerations, intense competition, rapid technological change and obsolescence, and government regulation. The fund may have additional volatility because it can invest a significant portion of assets in securities of a small number of individual issuers.

This description is only intended to provide a brief overview of the mutual fund. Read the fund's prospectus for more detailed information about the fund.

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FBIOX - Fidelity Select Biotechnology Portfolio | Fidelity ...

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Mtech Biotechnology Research and Education Program

Thursday, September 8th, 2016

MARYLAND TECHNOLOGY ENTERPRISE INSTITUTE

PATHS FOR MARYLAND ENTREPRENEURS & INNOVATORS

BIOTECHNOLOGY RESEARCH AND EDUCATION PROGRAM

Overview

Mtech's Biotechnology Research and Education Program (BREP) is the region's premier biotechnology, biopharmaceutical and biofuel research center, designed to bolster Maryland's burgeoning biotechnology industry. The program consists of two core facilities dedicated to providing supplemental research to academia, government and industry.

Bioprocessing Scale-Up Facility

(BSF)

The BSF offers a broad range of bioprocess scale-up and production services, including fermentation, cell culture, separation, purification and product analysis. The BSF's capabilities include up to 250-liter fermentations. Past clients have included Martek Biosciences, MedImmune, NIH, Digene, NIST, and the US Army. MORE >>>

Biopharmaceutical Advancement Facility (BAF)

The BAF specializes in the development of cell culture-based biopharmaceutical products. The facility's staff members offer extensive expertise in addressing challenging problems with the advancement of anchorage-dependent or suspension-adapted cell lines. MORE >>>

The Biotechnology Research and Education Program maintains strong links to the Clark School of Engineerings Fischell Department of Bioengineering which offers bachelors, masters and doctoral degree programs. The Clark School also offers a graduate certification in bioengineering.

Learn more about the Fischell Department of Bioengineering

BREP's expert staff offer customized training in many aspects of bioprocessing for Maryland biotech companies.

Productivity Enhancement: Biopharmaceutical Manufacturing Consulting

The most successful biomanufacturing companies utilize their resources efficiently. They bring products to market faster, meet production deadlines and minimize waste. The Biotechnology Research and Education Program's Productivity Enhancement consulting component applies improved manufacturing techniques to biomanufacturing.

BREP consultants' areas of expertise include facility design and layout, process optimization and load balancing, material handling, logistics, and cellular manufacturing. They can also help companies be more productive in:

BREP Staff utilize the following four-step approach for bio manufacturing consulting:

Companies planning a facility expansion or relocation can take advantage of the BREP staff's expert advice for contractor review, new equipment selection and floor layout design. Biotech team members can create computer simulations of the proposed facility to help companies evaluate alternative processing flows, while process development solutions can be tested in the BSF.

Perform higher, faster and more efficiently by employing BREP's Productivity Enhancement consulting services.

Ben Woodard

Director, Biotechnology Research and Education Program

tel. (301) 405-3909

fax. (301) 405-8213

woodard@umd.edu

Biotechnology Research and Education Program

Chemical and Nuclear Engineering Building #090

University of Maryland

College Park, MD 20740

2120 Potomac Bldg. 092

University of Maryland

College Park, MD 20742-3415

tel: 301.405.3906

fax: 301.403.4105

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Biotech, Pharmaceutical, Medical Device, and Chemical …

Thursday, September 8th, 2016

<-- Manitboa Biotech Company Name

City

Annapolis

Annapolis

Annapolis

Baltimore

Baltimore

Baltimore

Baltimore

Baltimore

Baltimore

Baltimore

Baltimore

Baltimore

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Baltimore

Bethesda

Bethesda

Bethesda

Clarksville

Cockeysville

Columbia

Columbia

Columbia

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Columbia

Columbia

Columbia

Elkridge

Frederick

Frederick

Fredrick

Frederick

Frederick

Frederick

Frederick

Gaithersburg

Gaithersburg

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Galena

Germantown

Germantown

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Glen Burnie

Hanover

Havre de Grace

Hunt Valley

Lexington Park

Rockville

Rockville

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Savage

Silver Spring

Sparks

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BioHealth and Life Sciences – Maryland is Open for Business

Thursday, September 8th, 2016

CAREERS

To post job/internship opportunities, employers must email BioHealth.info@Maryland.gov a request to post a job/internship link which includes the link to the job description (including application instructions, and the point of contacts name, title, organization address, phone and email.)

CurrentOpenings:

Dont miss the nextindustry event! Check out our calendar for a list ofBio events.

Marylands colleges and universities offer dozens of biohealth technology certificate, two and four year and advanced degree, continuing education and specialized training programs in fields ranging from nanotechnology to biomedical engineering, biotechnology manufacturing to clinical trials project management. A sampling of life sciences related programs are listed below. For more questions, or specific training needs, please contact the Maryland Department of Commerces Office of BioHealth and Life Sciencesfor more information.

Four Year Colleges and Universities:

Community Colleges:

The continuing growth of Biotechnology companies is dependent upon the level of training and education and skills of their workers. Marylands colleges and universities not only offer a wealth of biotechnology education and training programs, but also most willcustomize training targeted to specific needs. A number of private and nonprofit organizations also offer training. These programs include:

Bio-Trac

Bio-Trac offers hands-on biotechnology training workshops that are ideal for bench and research scientists. Team-taught by active researchers at a graduate/post graduate level, Bio-Trac workshops focus on the latest relevant technologies in cell and molecular biology. Bio-Trac provides custom designed training programs for government, private and academic institutions as well as conducting 20+ offerings at the Montgomery College Bioscience Education Center in Germantown, MD.

BioTRAIN

Training modules developed with industry input from board with large industry representation. In addition to designing training modules based in industry input, BioTRAIN staff work closely with Montgomery Colleges other Biotechnology certificate degree and programs to place students.

Biotechnical Institute (BTI)

Free skill-based scientific training provided to qualified adult high school graduates who are unemployed or underemployed to become entry-level biotechnicians/lab techs. BTI partners with Baltimore CC and has a successful placement record.

The Foundation for Advanced Education in the Sciences (FAES)

An array of management and leadership development seminars and workshops provided to help the medical science and public health community to advance their professional knowledge. FAES offers 120+ courses in 12 departments.

Maryland Tech Connection (MTC), operated out of Anne Arundel Workforce Development Corporation

Biotechnology and IT training for long term unemployed blending industry-led training and work and learn strategies with strong job seeker wrap-around supports. The program serves 12 counties and the city of Baltimore, and includes 59 partners.

Companies looking to open their first office in Maryland have a wide variety of incubators (with lab space and without wet lab space)to choose from. Use our incubator search tool to find the right space for you. Several of the incubators are housed inresearch parks where they have ample room to grow and leverage the parks resources. Browse through Marylandsresearch parks for a snapshot of what is available.

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BioHealth and Life Sciences - Maryland is Open for Business

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Biotechnology – Holy Cross College Notre Dame, Indiana

Sunday, August 28th, 2016

While at St. Edwards University in Austin, TX, I was awarded a Presidential Award in my last year as an undergraduate. I have a doctorate in microbiology, and I have worked with Ebola and Marburg viruses as a researcher at the Texas Biomedical Research Institute in San Antonio, TX, under the direction of Jean L. Patterson. In 2013, I published two peer-reviewed articles on my virus research.

When working with students, my main goal is to challenge them to become problem solvers. Facts in all fields of study are in continuous evolution, and students therefore must understand that texts provide the basis for future discovery. As an educator, I require my students to think about contemporary challenges in science which in turn would help them understand how they too can become contributors to scientific thought and understanding.

Martin Sulkanen, Ph.D. Associate Professor of Physics

My Ph.D. in physics from Cornell University led me to a post-doctoral fellowship at Los Alamos National Laboratory, and a career in astrophysics with companies and organizations such as NASA Marshall Flight Center, Michigan Research and Development Center, and Leidos, Inc. Because of my lifelong fascination with the profound consequences of the basic principles of physics on our universe, I have studied binary star systems, galactic radio jets, and worked on NASAs Chandra X-Ray Observatory Project Science Team.

As a professor of physics and mathematics, I encourage my students to develop an intuitive understanding for physics to guide the understanding of further mathematical analysis: dont get lost in the equations! My students have gone on to a variety of careers in places such as at Yale University, the International Space Station and the the US Patent & Trademark Office.

Yuhui Lu, Ph.D. Associate Professor of Chemistry

The study of chemistry is necessary for students who want to pursue a career in natural science, medical science, and engineering. It also helps liberal art students to improve their reasoning skills, understand scientific methodology, and gain deeper insight between human-nature relationships. I challenge all my students, regardless of background, to engage in logic, diligence, and self-discipline.

I have earned Ph.D.s in both chemistry and electrical engineering. I use this combination of disciplines to research nanoelectronics and single molecular devices with colleagues at the University of Notre Dame. I have also been a principal investigator of grants with the National Science Foundation, and undergraduate research supervisor. I am currently pursuing a variety of research opportunities for Holy Cross students.

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Biotechnology - Holy Cross College Notre Dame, Indiana

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Biotechnology | National Student Leadership Conference

Sunday, August 28th, 2016

Find solutions for a better world at the NSLC on Biotechnology. ';

The National Student Leadership Conference has a unique partnership with American University to offer college credit for our high school summer programs. The American University is distinguished as a premier global university and known for turning ideas into action and action into service. As a result of this NSLC/AU alliance, students attending the NSLCs summer programs for high school students have the opportunity to take college credit classes taught by American University faculty at all NSLC locations. This credit option enhances your education within the framework of your program experience, without interrupting NSLC activities.

Read more about earning college credit through your NSLC program.

Visit research labs Learn from scientists, doctors and engineers working in advanced research labs during exclusive hands-on tours.

Hands-on experiments Learn the basics of DNA manipulation during intensive biotech experiments.

Explore cutting-edge technologies used in the fields of medicine, energy production, agriculture, and bioengineering.

While at the NSLC, you will have the opportunity to step into the lab and learn hands-on the skills used in the field of biotechnology to manipulate DNA and create products like better medicines and cleaner fuels.

Lab experiences will include:

While at the NSLC on Biotechnology program, you will meet with and learn from leaders in the biotechnology field. In past years, guest speakers have included:

Dr. Francis S. Collins Director, National Institutes of Health

Dr. Ben Busby Computational Biology Branch, National Center for Biotechnology Information

Dr. Eric D. Green Director, National Human Genome Research Institute (NIH)

Dean Stephen Carr Associate Dean of Undergraduate Engineering, Northwestern University

Dr. Jon R. Lorsch Director, National Insitute of General Medical Sciences

Dr. Anthony S. Fauci Director, National Institute of Allergy and Infectious Diseases (NIH)

An important part of the NSLCs Biotechnology youth leadership program is seeing the sites around some of our nations greatest cities. These trips are designed as both sightseeing tours and exclusive educational trips specifically tailored to the area of Biotechnology:

At the heart of each of our youth leadership programs is a curriculum designed to build concrete leadership skills that will help you succeed. From the beginning of your program you will learn to work as a team during an exciting Ropes Challenge Course. Interactive lectures and small-group workshops will give you an opportunity to build upon your strengths and minimize your weaknesses.

Leadership topics tailored to the Biotechnology program include:

Tuition

Scholarships

Fundraising

Tuition

Your NSLC tuition is all-inclusive. Your tuition covers course materials, housing, on-campus meals, social events and transportation throughout your program.

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Program tuition is all-inclusive. It covers course materials, housing, on-campus meals, social events and transportation in air-conditioned motor coaches throughout the program. Each student is responsible for the cost of travel to and from the program as well as individual spending money.

Cancellation Fees and Refund Policy All cancellations must be submitted in writing (email is acceptable). The following cancellation fees apply to all NSLC enrollments:

NSLC will refund all funds minus the cancellation fee listed above. No refunds will be given after May 16th, 2016. Student Protection Plan fees for accepted students are non-refundable.

Instead of cancelling, you may elect to apply your total payments toward a program next year. If so, you will be enrolled in our 2017 Pre-Registration and sent an email in the fall of 2016 to select the program/session you wish to attend. Note: If you choose to cancel your enrollment and not attend a 2017 program, the cancellation fees above will still apply.

Note: If an application is rejected or if space in the program is not available, all deposits/payments will be refunded in full.

Scholarships

We offer a comprehensive scholarship program to assist qualified students with the cost of NSLC tuition, based on financial need, academic merit and extracurriculars.

Apply Now...

Fundraising

Fundraising is a great way to raise funds to contribute toward your NSLC program tuition while also forging relationships with leaders in your community.

Learn More...

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Biotechnology | National Student Leadership Conference

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Biotechnology Conferences | CPD Events| Biotechnology …

Monday, August 22nd, 2016

Frontiers in Biotechnology

Biotechnology is an innovative science in which living systems and organisms are used to develop new and useful products, ranging from healthcare products to seeds. The field of Biotechnology is growing rapidly making tremendous impacts in Medical/Health Care, Food & Agriculture. The Global Biotechnology industry is in the growth phase of its economic life cycle. Over the five years to 2014, revenue and industry value added (IVA) growth have outpaced world GDP growth. The Frontiers in Biotechnology track will cover current technological aspects that aim at obtaining products with scientific, industrial, health and agricultural applications, from organisms with increasing levels of complexity from bacteria, yeast, plants, animal cells and virus. With the lectures and demonstrations on stem cell therapy, Embryo transfer technology, next generation sequencing, Drug discovery, biotechnology in food and dairy, etc... The participants are expected to acquire knowledge in techniques and methodologies used in Biotechnology.

Pharmaceutical Biotechnology

Pharmaceutical Biotechnology is the science that covers all technologies required for producing, manufacturing and registration of biological drugs.Pharmaceutical Biotechnologyis an increasingly important area of science and technology. It contributes in design and delivery of new therapeutic drugs,diagnosticagents for medical tests, and in gene therapy for correcting the medical symptoms of hereditary diseases. The Pharmaceutical Biotechnology is widely spread, ranging from many ethical issues to changes inhealthcarepracticesand a significant contribution to the development of national economy.Biopharmaceuticalsconsists of large biological molecules which areproteins. They target the underlying mechanisms and pathways of a disease or ailment; it is a relatively young industry. They can deal with targets in humans that are not accessible withtraditional medicines.

Related Conferences

11th World Congress onBiotechnology and Biotech Industries Meet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 13thBiotechnology Congress, Nov 28-30, 2016, San Francisco, USA;Global Biotechnology Congress2016, May 11th - 14th 2016, Boston, MA, USA;Biomarker Summit2016, March 21-23, 2016 San Diego, CA, USA; 14thVaccines Research & Development, July 7-8, Boston, USA;Pharmaceutical & BiotechPatent Litigation Forum, Mar 14 - 15, 2016, Amsterdam, Netherlands; 4thBiomarkers in Diagnostics, Oct 07-08, 2015 Berlin, Germany, DEU.

Medical Biotechnology

Medicine is by means of biotechnology techniques so much in diagnosing and treating dissimilar diseases. It also gives opportunity for the population to defend themselves from hazardous diseases. The pasture of biotechnology, genetic engineering, has introduced techniques like gene therapy, recombinant DNA technologyand polymerase chain retort which employ genes and DNA molecules to make adiagnosis diseasesand put in new and strong genes in the body which put back the injured cells. There are some applications of biotechnology which are live their part in the turf of medicine and giving good results.

Related Conferences

11th World Congress onBiotechnology and Biotech Industries Meet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 13thBiotechnology Congress, Nov 28-30, 2016, San Francisco, USA;Global Biotechnology Congress2016, May 11th - 14th 2016, Boston, MA, USA;Biomarker Summit2016, March 21-23, 2016 San Diego, CA, USA; 14thVaccines Research & Development, July 7-8, Boston, USA;Pharmaceutical & Biotech Patent Litigation Forum, Mar 14 - 15, 2016, Amsterdam, Netherlands; 4thBiomarkers in Diagnostics, Oct 07-08, 2015 Berlin, Germany, DEU.

Molecular Biotechnology

Molecular biotechnology is the use of laboratory techniques to study and modify nucleic acids and proteins for applications in areas such as human and animal health, agriculture, and the environment.Molecular biotechnologyresults from the convergence of many areas of research, such as molecular biology, microbiology, biochemistry, immunology, genetics, and cell biology. It is an exciting field fueled by the ability to transfer genetic information between organisms with the goal of understanding important biological processes or creating a useful product.

Related Conferences

11th World Congress onBiotechnology and Biotech IndustriesMeet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 13thBiotechnology Congress, Nov 28-30, 2016, San Francisco, USA; GlobalBiotechnology Congress2016, May 11th-14th 2016, Boston, MA, USA;BIO Investor Forum, October 20-21, 2015, San Francisco, USA;BIO Latin America Conference, October 14-16, 2015, Rio de Janeiro, Brazil;Bio Pharm America 20158th Annual International Partnering Conference, September 15-17, 2015, Boston, MA, USA.

Environmental Biotechnology

The biotechnology is applied and used to study the natural environment. Environmental biotechnology could also imply that one try to harness biological process for commercial uses and exploitation. It is "the development, use and regulation of biological systems for remediation of contaminated environment and forenvironment-friendly processes(green manufacturing technologies and sustainable development). Environmental biotechnology can simply be described as "the optimal use of nature, in the form of plants, animals, bacteria, fungi and algae, to producerenewable energy, food and nutrients in a synergistic integrated cycle of profit making processes where the waste of each process becomes the feedstock for another process".

Related Conferences

11th World Congress onBiotechnology and Biotech IndustriesMeet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 13thBiotechnology Congress, Nov 28-30, 2016, San Francisco, USA; GlobalBiotechnology Congress2016, May 11th - 14th 2016, Boston, MA, USA;Biomarker Summit2016, March 21-23, 2016 San Diego, CA, USA; 14thVaccines Research & Development, July 7-8, Boston, USA;Pharmaceutical & BiotechPatent Litigation Forum, Mar 14 - 15, 2016, Amsterdam, Netherlands

Animal Biotechnology

It improves the food we eat - meat, milk and eggs. Biotechnology can improve an animals impact on the environment. Animalbiotechnologyis the use of science and engineering to modify living organisms. The goal is to make products, to improve animals and to developmicroorganismsfor specific agricultural uses. It enhances the ability to detect, treat and prevent diseases, include creating transgenic animals (animals with one or more genes introduced by human intervention), using gene knock out technology to make animals with a specific inactivated gene and producing nearly identical animals by somatic cell nuclear transfer (or cloning).

Related Conferences

11th World Congress onBiotechnology and Biotech Industries Meet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 13thBiotechnology Congress, Nov 28-30, 2016, San Francisco, USA;Global Biotechnology Congress2016, May 11th - 14th 2016, Boston, MA, USA;Biomarker Summit2016, March 21-23, 2016 San Diego, CA, USA; 14thVaccines Research & Development, July 7-8, Boston, USA;Pharmaceutical & BiotechPatent Litigation Forum, Mar 14 - 15, 2016, Amsterdam, Netherlands; 4thBiomarkers in Diagnostics, Oct 07-08, 2015 Berlin, Germany, DEU.

Agricultural Biotechnology

Biotechnology is being used to address problems in all areas of agricultural production and processing. This includesplant breedingto raise and stabilize yields; to improve resistance to pests, diseases and abiotic stresses such as drought and cold; and to enhance the nutritional content of foods. Modern agricultural biotechnology improves crops in more targeted ways. The best known technique is genetic modification, but the term agricultural biotechnology (or green biotechnology) also covers such techniques asMarker Assisted Breeding, which increases the effectiveness of conventional breeding.

Related Conferences

3rd GlobalFood Safety Conference, September 01-03, 2016, Atlanta USA; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 12thBiotechnology Congress, Nov 14-15, 2016, San Francisco, USA;Biologically Active Compoundsin Food, October 15-16 2015 Lodz, Poland; World Conference onInnovative Animal Nutrition and Feeding, October 15-17, 2015 Budapest, Hungary; 18th International Conference onFood Science and Biotechnology, November 28 - 29, 2016, Istanbul, Turkey; 18th International Conference on Agricultural Science, Biotechnology,Food and Animal Science, January 7 - 8, 2016, Singapore; International IndonesiaSeafood and Meat, 1517 October 2016, Jakarta, Indonesia.

Industrial Biotechnology

Industrial biotechnology is the application of biotechnology for industrial purposes, includingindustrial fermentation. The practice of using cells such as micro-organisms, or components of cells like enzymes, to generate industrially useful products in sectors such as chemicals, food and feed, detergents, paper and pulp, textiles andbiofuels. Industrial Biotechnology offers a premier forum bridging basic research and R&D with later-stage commercialization for sustainable bio based industrial and environmental applications.

Related Conferences

11th World Congress onBiotechnology and Biotech Industries Meet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 13thBiotechnology Congress, Nov 28-30, 2016, San Francisco, USA; GlobalBiotechnology Congress2016, May 11th - 14th 2016, Boston, MA, USA;Biomarker Summit2016, March 21-23, 2016 San Diego, CA, USA; 14thVaccines Research & Development, July 7-8, Boston, USA;Pharmaceutical & BiotechPatent Litigation Forum, Mar 14 - 15, 2016, Amsterdam, Netherlands; 4thBiomarkers in Diagnostics, Oct 07-08, 2015 Berlin, Germany, DEU.

Microbial Biotechnology

Microorganisms have been exploited for their specific biochemical and physiological properties from the earliest times for baking, brewing, and food preservation and more recently for producingantibiotics, solvents, amino acids, feed supplements, and chemical feedstuffs. Over time, there has been continuous selection by scientists of special strains ofmicroorganisms, based on their efficiency to perform a desired function. Progress, however, has been slow, often difficult to explain, and hard to repeat. Recent developments inmolecular biologyand genetic engineering could provide novel solutions to long-standing problems. Over the past decade, scientists have developed the techniques to move a gene from one organism to another, based on discoveries of how cells store, duplicate, and transfer genetic information.

Related conferences

3rdGlobal Food Safety Conference, September 01-03, 2016, Atlanta USA; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 12thBiotechnology Congress, Nov 14-15, 2016, San Francisco, USA;Biologically Active Compoundsin Food, October 15-16 2015 Lodz, Poland; World Conference onInnovative Animal Nutrition and Feeding, October 15-17, 2015 Budapest, Hungary; 18th International Conference onFood Science and Biotechnology, November 28 - 29, 2016, Istanbul, Turkey; 18th International Conference on Agricultural Science, Biotechnology,Food and Animal Science, January 7 - 8, 2016, Singapore; International IndonesiaSeafood and Meat, 1517 October 2016, Jakarta, Indonesia.

Food Biotechnology

Food processing is a process by which non-palatable and easily perishable raw materials are converted to edible and potable foods and beverages, which have a longer shelf life. Biotechnology helps in improving the edibility, texture, and storage of the food; in preventing the attack of the food, mainly dairy, by the virus like bacteriophage producing antimicrobial effect to destroy the unwanted microorganisms in food that cause toxicity to prevent the formation and degradation of other toxins andanti-nutritionalelements present naturally in food.

Related Conferences

11th World Congress onBiotechnology and Biotech Industries Meet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 13thBiotechnology Congress, Nov 28-30, 2016, San Francisco, USA;Global Biotechnology Congress 2016, May 11th-14th 2016, Boston, MA, USA;BIO Investor Forum, October 20-21, 2015, San Francisco, USA;BIO Latin America Conference, October 14-16, 2015, Rio de Janeiro, Brazil;Bio Pharm America 20158th Annual International Partnering Conference, September 15-17, 2015, Boston, MA, USA.

Genetic Engineering and Biotechnology

One kind of biotechnology is gene technology, sometimes called 'genetic engineering' or'genetic modification', where the genetic material of living things is deliberately altered to enhance or remove a particular trait and allow the organism to perform new functions. Genes within a species can be modified, or genes can be moved from one species to another. Genetic engineering has applications inmedicine, research, agriculture and can be used on a wide range of plants, animals and microorganisms. It resulted in a series of medical products. The first two commercially prepared products from recombinant DNA technology were insulin andhuman growth hormone, both of which were cultured in the E. coli bacteria.

The field of molecular biology overlaps with biology and chemistry and in particular, genetics and biochemistry. A key area of molecular biology concerns understanding how various cellular systems interact in terms of the way DNA, RNA and protein synthesis function.

Related Conferences

11th World Congress onBiotechnology and Biotech Industries Meet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 13thBiotechnology Congress, Nov 28-30, 2016, San Francisco, USA;Global Biotechnology Congress2016, May 11th - 14th 2016, Boston, MA, USA;Biomarker Summit2016, March 21-23, 2016 San Diego, CA, USA; 14thVaccines Research & Development, July 7-8, Boston, USA;Pharmaceutical & BiotechPatent Litigation Forum, Mar 14 - 15, 2016, Amsterdam, Netherlands; 4thBiomarkers in Diagnostics, Oct 07-08, 2015 Berlin, Germany, DEU.

Biotechnology Investor & partnering Forum

The Biotech Investor & Partnering Forum is one of the unique conclave focused on the management and economics of biotechnology which became so important as the field is growing on a fast paced. From agriculture and environment sectors to pharmaceutical and healthcare products and services, the industries and institutions emerging from the biotech revolution Bio-Based Economy represent one of the largest and most steadily growing building blocks of the Global economy. The social impact is overwhelming, generating tremendous progress in quality of life but also difficult issues that needs responsible management based on consumer & bio-industry perspective, solid ethical principles, growing intellectual property rights complexity, long drug development times, Bio security, unusual market structures and highly unpredictable outcomes are just some of the challenges facing biotechnology management today.

Related Conferences

11th World Congress onBiotechnology and Biotech Industries Meet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 13thBiotechnology Congress, Nov 28-30, 2016, San Francisco, USA;Global Biotechnology Congress2016, May 11th - 14th 2016, Boston, MA, USA;Biomarker Summit2016, March 21-23, 2016 San Diego, CA, USA; 14thVaccines Research & Development, July 7-8, Boston, USA;Pharmaceutical & BiotechPatent Litigation Forum, Mar 14 - 15, 2016, Amsterdam, Netherlands; 4thBiomarkers in Diagnostics, Oct 07-08, 2015 Berlin, Germany, DEU.

Nano Biotechnology

Nano biotechnology, bio nanotechnology, and Nano biology are terms that refer to the intersection of nanotechnology and biology. Bio nanotechnology and Nano biotechnology serve as blanket terms for various related technologies. The most important objectives that are frequently found inNano biologyinvolve applying Nano tools to relevantmedical/biologicalproblems and refining these applications. Developing new tools, such as peptide Nano sheets, for medical and biological purposes is another primary objective in nanotechnology.

Related Conferences

8thWorldMedicalNanotechnologyCongress& Expo during June 9-11, Dallas, USA; 6thGlobal Experts Meeting and Expo onNanomaterialsand Nanotechnology, April 21-23, 2016 ,Dubai, UAE; 12thNanotechnologyProductsExpo, Nov 10-12, 2016 at Melbourne, Australia; 5thInternationalConference onNanotekand Expo, November 16-18, 2015 at San Antonio, USA; 11thInternational Conference and Expo onNano scienceandMolecular Nanotechnology, September 26-28 2016, London, UK; 18thInternational Conference onNanotechnologyand Biotechnology, February 4 - 5, 2016 in Melbourne, Australia; 16thInternational Conference onNanotechnology, August 22-25, 2016 in Sendai, Japan; International Conference onNano scienceand Nanotechnology, 7-11 Feb 2016 in Canberra, Australia; 18thInternational Conference onNano scienceand Nanotechnology, February 15 - 16, 2016 in Istanbul, Turkey; InternationalNanotechnologyConference& Expo, April 4-6, 2016 in Baltimore, USA.

Animal biotechnology

Animal biotechnology is a branch of biotechnology in which molecular biology techniques are used to genetically engineer animals in order to improve their suitability for pharmaceutical, agricultural or industrial applications. Many animals also help by serving as models of disease. If an animal gets a disease that's similar to humans, we can use that animal to test treatments. Animals are often used to help us understand how new drugs will work and whether or not they'll be safe for humans and effective in treating disease.

Related conferences

11th World Congress onBiotechnology and Biotech IndustriesMeet, July 28-29, 2016, Berlin, Germany; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 12thBiotechnology Congress, Nov 14-15, 2016, San Francisco, USA;BIO IPCC Conference, Cary, North Carolina, USA; World Congress onIndustrial Biotechnology, April 17-20, 2016, San Diego, CA; 6thBio based Chemicals: Commercialization & Partnering, November 16-17, 2015, San Francisco, CA, USA; The European Forum forIndustrial Biotechnology and Bio economy, 27-29 October 2015, Brussels, Belgium; 4thBiotechnology World Congress, February 15th-18th, 2016, Dubai, United Arab Emirates; International Conference on Advances inBioprocess Engineering and Technology, 20th to 22nd January 2016,Kolkata, India; GlobalBiotechnology Congress2016, May 11th - 14th 2016, Boston, MA, USA

Biotechnology Applications

Biotechnology has application in four major industrial areas, including health care (medical), crop production and agriculture, nonfood (industrial) uses of crops and other products (e.g. biodegradable plastics, vegetable oil, biofuels), and environmental uses. AppliedMicrobiologyand Biotechnology focusses on prokaryotic or eukaryotic cells, relevant enzymes and proteins, applied genetics and molecular biotechnology,genomicsand proteomics, applied microbial and cell physiology, environmental biotechnology, process and products and more.

Related conferences

3rd GlobalFood Safety Conference, September 01-03, 2016, Atlanta USA; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, Thailand; 11thEuro Biotechnology Congress, November 07-09,2016, Alicante Spain; 12thBiotechnology Congress, Nov 14-15, 2016, San Francisco, USA;Biologically Active Compoundsin Food, October 15-16 2015 Lodz, Poland; World Conference onInnovative Animal Nutrition and Feeding, October 15-17, 2015 Budapest, Hungary; 18th International Conference onFood Science and Biotechnology, November 28 - 29, 2016, Istanbul, Turkey; 18th International Conference on Agricultural Science, Biotechnology,Food and Animal Science, January 7 - 8, 2016, Singapore; International IndonesiaSeafood and Meat, 1517 October 2016, Jakarta, Indonesia.

Biotechnology Companies & Market Analysis

From agriculture to environmental science, biotechnology plays an important role in improving industry standards, services, and developing new products. Biotechnology involves the spectrum of life science-based research companies working ontransformative technologiesfor a wide range of industries. While agriculture, material science and environmental science are major areas of research, the largest impact is made in the field medicine. As a large player in the research and development of pharmaceuticals, the role ofbiotechnologyin the healthcare field is undeniable. From genetically analysis and manipulation to the formation of new drugs, many biotech firms are transforming into pharmaceutical and biopharmaceutical leaders.

Related conferences

10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok; 11thEuroBiotechnologyCongress, November 7-9, 2016 Alicante, Spain; 11th World Congress onBiotechnology and Biotech IndustriesMeet, July 28-29, 2016, Berlin, Germany; 13thBiotechnologyCongress, November 28-30, 2016 San Francisco, USA; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, UAE;BioInternational Convention, June 6-9, 2016 | San Francisco, CA;BiotechJapan, May 11-13, 2016, Tokyo, Japan;NANO BIOEXPO 2016, Jan. 27 - 29, 2016, Tokyo, Japan;ArabLabExpo2016, March 20-23, Dubai; 14thInternational exhibition for laboratory technology,chemical analysis, biotechnology and diagnostics, 12-14 Apr 2016, Moscow, Russia

Biotechnology Capital & Grants

Every new business needs some startup capital, for research, product development and production, permits and licensing and other overhead costs, in addition to what is needed to pay your staff, if you have any. Biotechnology products arise from successfulbiotechcompanies. These companies are built by talented individuals in possession of a scientific breakthrough that is translated into a product or service idea, which is ultimately brought into commercialization. At the heart of this effort is the biotech entrepreneur, who forms the company with a vision they believe will benefit the lives and health of countless individuals. Entrepreneurs start biotechnology companies for various reasons, but creatingrevolutionary productsand tools that impact the lives of potentially millions of people is one of the fundamental reasons why all entrepreneurs start biotechnology companies.

10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok; 11thEuroBiotechnologyCongress, November 7-9, 2016 Alicante, Spain; 11th World Congress onBiotechnology and Biotech IndustriesMeet, July 28-29, 2016, Berlin, Germany; 13thBiotechnologyCongress, November 28-30, 2016 San Francisco, USA; 10thAsia Pacific Biotech CongressJuly 25-27, 2016, Bangkok, UAE;BioInternational Convention, June 6-9, 2016 | San Francisco, CA;BiotechJapan, May 11-13, 2016, Tokyo, Japan;NANO BIOEXPO 2016, Jan. 27 - 29, 2016, Tokyo, Japan;ArabLabExpo2016, March 20-23, Dubai; 14thInternational exhibition for laboratory technology,chemical analysis, biotechnology and diagnostics, 12-14 Apr 2016, Moscow, Russia

Scope and Importance

From the simple facts of brewing beer and baking bread has emerged a field now known asBiotechnology. Over the ages the meaning of the word biotechnology has evolved along with our growing technical knowledge. Biotechnology began by using cultured microorganisms to create a variety of food and drinks, despite in early practitioners not even knowing the existence of microbial world. Today, biotechnology is still defined as many application of living organisms or bioprocesses to create new products. Although the underlying idea is unchanged, the use of genetic engineering and other modern scientific techniques has revolutionized the area.

The field of genetics, molecular biology, microbiology, and biochemistry are merging their respective discoveries into the expanding applied field of biotechnology, and advances are occurring at a record pace. Traditional biotechnology goes back thousands of years.

Modern biotechnology applies not only modern genetics but also advances in other sciences. However, there is a third revolution that is just emergingnanotechnology. The development of techniques to visualize and manipulate atoms individually or in small clusters is opening the way to an ever-finer analysis of living systems. Nanoscale techniques are now beginning to play significant roles in many area of biotechnology.

This raises the question of what exactly defines biotechnology. To this there is no real answer. Today, the application of modern genetics or other equivalent modern technology is usually seen as application of modern genetics or equivalent modern technology is usually seen as necessary for a process to count as biotechnology. Thus, the definition of biotechnology has become partly a matter of fashion. Therefore, to classical terms, (modern) biotechnology as resulting in a broaden manner from the merger of classical biotechnology with modern genetics, molecular biology, computer technology, and nanotechnology.

Biotech Congress 2017covers mostly all the allied areas of biotechnology which embraces both the basic sciences, technology and as well as its applications in research, industry and academia. This conference will promote global networking between researchers, institutions, investors, industries, policy makers and students. The conference varied topics in biotechnology like healthcare, environmental, animal, plant, marine, genetic engineering, industrial aspects, food science and bio process.

Through this conference we can get all the relevant information regarding how we can use the advances in the biotechnology for building a better tomorrow by reducing the environmental impacts.

Why Italy?

Rome is the capital of Italy; it is also the countrys largest and most populated comune and fourth-most populous city in the European Union. The Metropolitan City of Rome has a population of 4.3 million residents. The city is located in the central-western portion of the Italian Peninsula, within Lazio (Latium), along the shores of Tiber River. Vatican City is an independent country within the city boundaries of Rome, the only existing example of a country within a city: for this reason Rome has been often defined as capital of two states. Roman mythology dates the founding of Rome at only around 753 BC; the site has been inhabited for much longer, making it one of the oldest continuously occupied cities in Europe. It is referred to as Roma Aeterna (The Eternal City) and Caput Mundi (Capital of the World), two central notions in ancient Roman culture. One of the most important city, Rome, was founded in 753 B.C. by Romulus.

The Apennine Mountains form its backbone and stretch from north to south, with the Tiber River cutting through them in central Italy. Along the northern border, the Alps serve as a natural boundary. The three major bodies of water surrounding Italy are the Adriatic Sea, the Ionian Sea, and the Mediterranean Sea. Ancient Rome is characterized by the seven hills and the Tiber River. The Tiber River flows from the Apennine Mountain, to the Tyrrhenian Sea.

Rome is a sprawling, cosmopolitan city with nearly 3,000 years of globally influential art, architecture and culture on display. In 2005, the city received 19.5 million global visitors, up of 22.1% from 2001. Rome ranked in 2014 as the 14thmos-visited city in the world, 3rd most visited in the European Union, and the most popular tourist attraction in Italy. Its historic center is listed by UNESCO as a World Heritage Site. Monuments and museums such as the Vatican Museums and the Colosseum are among the worlds most visited tourist destinations with both locations receiving millions of tourists a year. Rome hosted the 1960 Summer Olympics and is the seat of United Nations Food and Agriculture Organization (FAO).Rome is the city with the most monuments in the world.

The weather is fantastic in Rome in June, when the average temperature starts off at around 20C and gradually climbs up to 23C-24C as the month progresses.

Congress Highlights:

Biotech Congress 2017 emphasizes on:

Target Audience

CEO, Directors, Vice Presidents, Co-directors, Biotechnologists, Academicians, Biostatistician, Biotechnologists, Clinical Laboratory Scientist, Clinical Metabolomics Data Analyst, Clinicians, Commissioner of Health, Community health workers, CROs, Directors, Environmental Scientists, Food Scientists, Genetic Engineers, Health Economist, Health officials, Healthcare Analyst, Manager of Quality Assurance and Evaluation, Market Access Manager, Marketing Intelligence Associate, Master/PhD students, Medical professionals, Microbiologists, Pharmaceutical Scientists, Physicians, Plant Scientists, Postdoctoral Fellows, Public Health Officer, Public Health Policy Analyst, Research Associates, Research Coordinator, Research Data Analyst, Research Intern, Researchers and faculty, Scientific and Medical Information Assistant, Scientists, Food, Environmental & Plant Scientists, Clinicians, Professors, Health care industrialists, Post Doctorate Fellows, Brand Manufacturers of Consumer Products/ Managers, Pharmaceutical Scientists, Students.

Focusing areas to get more participations & Exhibitions

Why to attend?

Biotech Congress is a remarkable event which brings together a unique and international mix of Biotechnology Researchers, Industrial Biotechnologists, leading Universities and Research Institutions making the congress a perfect platform to share experience, foster collaboration across Industry and Academia, and evaluate emerging technologies across the globe.

Biotechnology in Europe

Only in March a market analysis by British researchers at the University of Cambridge had calculated a market potential of three billion euros for Europe.At present, such Crowd Investing platforms only have a market share of 6.5%, however, the growth forecasts are good. The biotech industry in Europe spends nearly $7.32 billion in R&D and $23.2 billion in revenue. Around 20% of the total marketed medicines, and as much as 50% of all drugs that are in the pipeline, are all healthcare biotech products. The European biotech industry provides employment to approximately 95,000 people. Biotechnology sector makes a substantial contribution to the fundamental EU policy objectives, such as job creation, economic growth, ageing society, public health, environmental protection and sustainable development.

Biotechnology in Italy

The Italian Biotechnology Report by Ernst&Young and Assobiotec, in cooperation with Farmindustria and Italian Trade Promotion Agency, shows that the Italian biotech companies are able to compete outstandingly on the international market, managing to grow despite continuing difficulties in the economic situation. With 394 companies, of which 248 pure biotech, Italy is third in Europe after Germany and the United Kingdom, for the number of pure biotech companies, with a growth trend (+2,5%) in clear contrast with that of the countries that occupy the top ranking positions. With 206 companies operating in the health-care field, the red biotech is the prevalent sector. Looking at the other sectors, 43 green biotech, 34 white biotech, 61 GPET (Genomics, Proteomics and Enabling Technologies) and 50 multi core companies are operating in Italy. 77% of the companies are small (less than 50 employees) and micro (less than 10 employees) enterprises, mainly located in Science and Technology Parks or Incubators. Total revenues in the biotech field amount to 7 billion Euros (+4%). Investments in R&D amount to 1,8 billion Euros (+8%), equal to 25% of total revenues. Italian biotech revenues contributes to 0,7% of GDP and the sector is being considered more and more often as a meta-sector, able to create value and employment and with significant effects on various fields, ranging from textiles to detergents, cosmetics, polymers, paper and animal feed, from paints to food, from treatment of waste to leather treatment, and many others. The future trends of Italian red biotech are connected to a further specialization in oncology, neurology and infectious diseases and to new achievements in the fields of Advanced Therapies and personalized medicine. The analysis of the Italian biotech pipeline shows 319 products for therapeutic use, of which 80 in the preclinical phase, 43 in Phase I, 98 in Phase II and 98 in Phase III. Plant genomics and traceability, preservation and safety of foods, as well as bioremediation and biomasses, are the most promising applications in the green & white fields.

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About BIO | BIO

Thursday, August 18th, 2016

BIO is the world's largest trade association representing biotechnology companies, academic institutions, state biotechnology centers and related organizations across the United States and in more than 30 other nations. BIO members are involved in the research and development of innovative healthcare, agricultural, industrial and environmental biotechnology products. BIO also produces theBIO International Convention, the worlds largest gathering of the biotechnology industry, along with industry-leading investor and partnering meetings held around the world.BIOtechNOWis BIO's blog chronicling innovations transforming our world and the BIO Newsletter is the organizations bi-weekly email newsletter.Subscribe to the BIO Newsletter.

Corporate members range from entrepreneurial companies developing a first product to Fortune 500 multinationals. We also represent state and regional biotech associations, service providers to the industry, and academic centers. Our members help foster a healthy economy by creating good-paying, biotechnology jobs.

Not only do we advocate for our members, but we also work towards enriching the industry with networking, partnering and education opportunities. We organize the BIO International Convention, the global event for biotechnology, along with many other industry-leading investor and partnering events held around the world. In addition, we produce BIOtechNOW, an online portal and monthly newsletter chronicling innovations transforming our world.

BIO is organized into four different sections to best represent our members and their goals:

We serve the needs of small-to-medium size companies, most of whom do not yet have major products approved and on the market. Whether advocating for pro-innovation tax policies to encouraging an economic and policy environment to foster biotech investment, we focus on critical issues affecting smaller companies and build programs to enhance their development.

We promote biomedical innovation by developing and advocating for public policies that represent the best interests of members focused on human health. We break-down the barriers that impede American innovation by reducing bureaucratic hurdles to lifesaving technologies. Among the priority issues are matters affecting the healthcare-related regulatory and reimbursement climate, pandemic and biodefense preparedness, publicly funded scientific research, and personalized medicine.

We promote the use of industrial enzymes, conversion of biomass to energy and chemicals, and innovative clean up technologies. We work closely with the U.S. Congress, federal agencies, and international organizations to encourage the development of technologies that make our lives and environment cleaner, safer and healthier.

We create and advance industry policies on all food and agriculture biotechnology issues related to international affairs, government relations, science and regulatory affairs, and media and public affairs. We work for a safe and clean supply of healthy food for a growing global population.

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Biotechnology for Biofuels | Home page

Thursday, August 4th, 2016

Prof James du Preez is professor of microbiology and former chairperson (2002 2014) of the Department of Microbial, Biochemical & Food Biotechnology at the University of the Free State in Bloemfontein, South Africa. He obtained his PhD in microbiology from the above university in 1980 after completing a major part of his doctoral research at the Swiss Federal Institute of Technology, Zrich, which laid the foundation for his further work in the field of fermentation biotechnology. His special interests include continuous (chemostat) cultures, yeast physiology, the production of heterologous proteins and microbial metabolites, as well as bioethanol production from starchy and lignocellulosic feedstocks, including pentose fermentation by yeasts. The physiology of the yeast Saccharomyces cerevisiae is an ongoing interest.

James has authored close to 100 peer-reviewed articles as well as several other papers and book chapters. Involvement with the science community includes membership of the council of the South African Society for Microbiology and the International Commission for Yeasts. He was the American Society for Microbiologys ambassador to South Africa until 2014. He serves on the editorial board of FEMS Yeast Research and was a guest editor for a thematic issue of FEMS Yeast Research on yeast fermentations and other yeast bioprocesses. He was an associate editor for World Journal of Microbiology and Biotechnology until early 2015, currently is a joint editor-in-chief for Biotechnology for Biofuels and recently served on the Editors Advisory Group of BioMed Central. In 2014 he was appointed external expert on the Biological Production Systems panel of the Swedish Foundation for Strategic Research and in 2015 served for a second term on a grant evaluation panel of the European Research Council. Among honours received are election as member of the Academy of Science of South Africa, the award of a silver medal for exceptional achievement from the South African Society for Microbiology and awards from his home university for research excellence.

Dr Michael Himmel has 30 years of progressive experience in conducting, supervising, and planning research in protein biochemistry, recombinant technology, enzyme engineering, new microorganism discovery, and the physicochemistry of macromolecules. He has also supervised research that targets the application of site-directed-mutagenesis and rational protein design to the stabilization and improvement of important industrial enzymes, especially glycosyl hydrolases.

Dr Himmel has functioned as PI for the DOE EERE Office of the Biomass Program (OBP) since 1992, wherein his responsibilities have included managing research designed to improve cellulase performance, reduce biomass pretreatment costs, and improve yields of fermentable sugars. He has also developed new facilities at NREL for biomass conversion research, including a Cellulase Biochemistry Laboratory, a Biomass Surface Characterization Laboratory, a Protein Crystallography Laboratory, and a new Computational Science Team. Dr. Himmel also serves as the Principal Group Manger of the Biomolecular Sciences Group, where he has supervisory responsibly for 50 staff scientists.

Prof Debra Mohnen received her B.A. in biology from Lawrence University (Wisconsin) and her MS in botany and PhD in plant biology from the University of Illinois. Her PhD research was conducted at the Friedrich Miescher Institute in Basel, Switzerland. She held postdoctoral research associate positions at the USDA's Richard Russell Research Center and at the Complex Carbohydrate Research Center (CCRC) in Athens, GA where she won an NIH National Research Service Award for her postdoctoral research. She was appointed to the CCRC faculty in September 1990 and is currently Professor in the Department of Biochemistry and Molecular Biology and also adjunct faculty member in the Department of Plant Biology and member of the Plant Center at UGA. Dr Mohnen has served on the Committee on the Status of Women in Plant Physiology of the American Society of Plant Physiologists, invited faculty sponsor for the UGA Association for Women in Science (AWIS), past member-at-large in the Cellulose and Renewable Materials Division of the American Chemical Society, and is currently a member of the Council for Chemical and Biochemical Sciences, Chemical Sciences, Geosciences, and Biosciences Division in the Office of Basic Energy Sciences, Office of Science, U.S. Department of Energy. As Co-PI on the NSF-funded Plant Cell Wall Biosynthesis Research Network Dr Mohnen established the originally NSF-funded service CarboSource Services, that provides rare substrates for plant wall polysaccharide synthesis to the research community. Her research centers on the biosynthesis, function and structure of plant cell wall polysaccharides is supported by funding from the USDA, NSF and DOE. Her emphasis is on pectin biosynthesis and pectin function in plants and human health, and on the improvement of plant cell wall structure so as to improve the efficiency of conversion of plant wall biomass to biofuels.

Prof Charles Wyman has devoted most of his career to leading advancement of technology for biological conversion of cellulosic biomass to ethanol and other products. In the fall of 2005, he joined the University of California at Riverside as a Professor of Chemical and Environmental Engineering and the Ford Motor Company Chair in Environmental Engineering with a research focus on pretreatment, enzymatic hydrolysis, and dehydration of cellulosic biomass to produce reactive intermediates for conversion to fuels and chemicals. Before joining UCR, he was the Paul E. and Joan H. Queneau Distinguished Professor in Environmental Engineering Design at the Thayer School of Engineering at Dartmouth College. Dr. Wyman recently founded Vertimass LLC that is devoted to commercialization of novel catalytic technology for simple one-step conversion of ethanol to fungible gasoline, diesel, and jet fuel blend stocks. Dr. Wyman is also cofounder and former Chief Development Officer and Chair of the Scientific Advisory Board for Mascoma Corporation, a startup focused on biomass conversion to ethanol and other products.

Before joining Dartmouth College in the fall of 1998, Dr. Wyman was Director of Technology for BC International and led process development for the first cellulosic ethanol plant planned for Jennings, Louisiana. Between 1978 and 1997, he served as Director of the Biotechnology Center for Fuels and Chemicals at the National Renewable Energy Laboratory (NREL) in Golden, Colorado; Director of the NREL Alternative Fuels Division; and Manager of the Biotechnology Research Branch. During that time, he held several other leadership positions at NREL, mostly focused on R&D for biological conversion of cellulosic biomass to fuels and chemicals. He has also been Manager of Process Development for Badger Engineers, an Assistant Professor of Chemical Engineering at the University of New Hampshire, and a Senior Chemical Engineer with Monsanto Company.

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Current Opinion in Biotechnology – Journal – Elsevier

Thursday, August 4th, 2016

The Current Opinion journals were developed out of the recognition that it is increasingly difficult for specialists to keep up to date with the expanding volume of information published in their subject. In Current Opinion in Biotechnology, we help the reader by providing in a systematic manner: 1. The views of experts on current advances in biotechnology in a clear and readable form. 2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications.

Division of the subject into sections The subject of biotechnology is divided into themed sections, each of which is reviewed once a year. The amount of space devoted to each section is related to its importance.

Analytical biotechnology Plant biotechnology Food biotechnology Energy biotechnology Environmental biotechnology Systems biology Nanobiotechnology Tissue, cell and pathway engineering Chemical biotechnology Pharmaceutical biotechnology

Selection of topics to be reviewed Section Editors, who are major authorities in the field, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasised. Section Editors commission reviews from authorities on each topic that they have selected.

Reviews Authors write short review articles in which they present recent developments in their subject, emphasising the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous year.

Editorial Overview Section Editors write a short overview at the beginning of the section to introduce the reviews and to draw the reader's attention to any particularly interesting developments. This successful format has made Current Opinion in Biotechnology one of the most highly regarded and highly cited review journals in the field (Impact factor = 8.035).

Ethics in Publishing: General Statement

The Editor(s) and Publisher of this Journal believe that there are fundamental principles underlying scholarly or professional publishing. While this may not amount to a formal 'code of conduct', these fundamental principles with respect to the authors' paper are that the paper should: i) be the authors' own original work, which has not been previously published elsewhere, ii) reflect the authors' own research and analysis and do so in a truthful and complete manner, iii) properly credit the meaningful contributions of co-authors and co-researchers, iv) not be submitted to more than one journal for consideration, and v) be appropriately placed in the context of prior and existing research. Of equal importance are ethical guidelines dealing with research methods and research funding, including issues dealing with informed consent, research subject privacy rights, conflicts of interest, and sources of funding. While it may not be possible to draft a 'code' that applies adequately to all instances and circumstances, we believe it useful to outline our expectations of authors and procedures that the Journal will employ in the event of questions concerning author conduct. With respect to conflicts of interest, the Publisher now requires authors to declare any conflicts of interest that relate to papers accepted for publication in this Journal. A conflict of interest may exist when an author or the author's institution has a financial or other relationship with other people or organizations that may inappropriately influence the author's work. A conflict can be actual or potential and full disclosure to the Journal is the safest course. All submissions to the Journal must include disclosure of all relationships that could be viewed as presenting a potential conflict of interest. The Journal may use such information as a basis for editorial decisions and may publish such disclosures if they are believed to be important to readers in judging the manuscript. A decision may be made by the Journal not to publish on the basis of the declared conflict.

For more information, please refer to: http://www.elsevier.com/wps/find/authorshome.authors/conflictsofinterest

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Best Master’s Degrees in Biotechnology 2016

Thursday, August 4th, 2016

Biotechnology is a top-notch field of study that emerged into the scientific world as a result of revolutions in Biology, Chemistry, Informatics, and Engineering. It is considered to be an applied branch of Biology. Biotechnology helps out this old and respectable field of science keep up with the pace of time and remain competitive in the contemporary world.

With a Master in Biotechnology, students will study the use of living organisms and bioprocesses in technology, engineering, medicine, agriculture and results in all kinds of bioproducts, from genetically modified food to serious cutting-edge devices used to carry out gene therapy. Students in Master in Biotechnology programs may also explore bioinformatics, which is the application of statistics and computer science to the field of molecular biology. Bioinformatics is extremely important for contemporary biological and molecular researches because the data amount there grows by geometric progression and it is necessary to have adequate technology to process it. Bioinformatic methods are widely used for mapping and analyzing DNA and protein samples, as well as for the study of genetics and molecular modeling. Biotechnology and Bioinformatics do a great favour to traditional fields of study, refreshing them with new methods of research, which allows their drastic development, and you can make your contribution with a Master in Biotechnology degree.

Find out about various Master in Biotechnology programs by following the links below. Don't hesitate to send the "Request free information" form to come in contact with the relevant person at the school and get even more information about the specific Master in Biotechnology program you are interested in.

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Biotechnology – Ivy Tech Community College of Indiana

Thursday, August 4th, 2016

The biotechnology program at Ivy Tech is taught by instructors with real-world experience. Students will use state-of-the-art laboratories that are equipped with instrumentation, supplies and equipment for an effective hands-on laboratory experience.

Classes focus on teaching a variety of procedures necessary to execute laboratory projects assigned in the students chosen field. Students will spend a significant amount of class time working hands-on doing laboratory activities either by themselves or in small groups with the ability to have one-on-one time with the instructor.

The Biotechnology Program prepares students for careers in a variety of life science and manufacturing settings including research, quality control, pharmaceuticals, and medical devise manufacturing.

Graduates will have the foundation needed to transfer to earn a bachelors degree or move right in to local, high-paying jobs in the community, including with some of our industry partners like Dow Agroscience, Eli Lilly, Cook Pharmica, Midwest Compliance Laboratories, and more. These great partnerships lead to our graduates high job placement rate.

*According to a Battelle/Biotechnology Industry Organization (BIO) Report State Biosciences Jobs, Investments and Innovation 2014.

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biotechnology – BIO | Healing, Fueling and Feeding the World

Thursday, August 4th, 2016

Recent advances in biotechnology are helping us prepare for and meet societys most pressing challenges.

At its simplest, biotechnology is technology based on biology - biotechnology harnesses cellular and biomolecular processes to develop technologies and products that help improve our lives and the health of our planet. We have used the biological processes of microorganisms for more than 6,000 years to make useful food products, such as bread and cheese, and to preserve dairy products.

Modern biotechnology provides breakthrough products and technologies to combat debilitating and rare diseases, reduce our environmental footprint, feed the hungry, use less and cleaner energy, and have safer, cleaner and more efficient industrial manufacturing processes.

Currently, there are more than 250 biotechnology health care products and vaccines available to patients, many for previously untreatable diseases. More than 18 million farmers around the world use agricultural biotechnology to increase yields, prevent damage from insects and pests and reduce farming's impact on the environment. And more than 50 biorefineries are being built across North America to test and refine technologies to produce biofuels and chemicals from renewable biomass, which can help reduce greenhouse gas emissions.

Recent advances in biotechnology are helping us prepare for and meet societys most pressing challenges. Here's how:

Biotech is helping toheal the worldby harnessing nature's own toolbox and using our own genetic makeup to heal and guide lines of research by:

Biotech uses biological processes such as fermentation and harnesses biocatalysts such as enzymes, yeast, and other microbes to become microscopic manufacturing plants. Biotech is helping tofuel the worldby:

Biotech improves crop insect resistance, enhances crop herbicide tolerance and facilitates the use of more environmentally sustainable farming practices. Biotech is helping tofeed the worldby:

Source: Healing, Fueling, Feeding: How Biotechnology is Enriching Your Life

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Biotechnology – Academic Majors (NDSU)

Thursday, August 4th, 2016

Biotechnology is an interdisciplinary field that uses a combination of biology and technology to design and produce new molecules, plants, animals and microorganisms with improved characteristics. Biotechnology offers seemingly unlimited opportunities to combine genes from related or unrelated species to produce useful organisms with desirable properties that were not previously found in nature.

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Biotechnology may be thought of as a collection of technologies using animal and/or plant cells, biological molecules, molecular biology processes and genetic engineering for applications in medicine, agriculture and the pharmaceutical industry. The technologies include the use of recombinant DNA for gene cloning and gene transfers between organisms; culture of plant and animal cells and tissues; fusion of animal cells or plant protoplast; the regeneration of whole plants from single cells and the large-scale fermentation processes that use some of these novel organisms for the production of pharmaceuticals, diagnostic tests for diseases, feed additives, enzymes and hormones.

Examples of successful biotechnology include the development of crop plants that are resistant to herbicides or insects, the production of human growth hormone and insulin by genetically engineered bacteria and the development of unique vaccines.

The biotechnology program is offered through both the College of Agriculture, Food Systems, and Natural Resources and the College of Science and Mathematics and leads to a Bachelor of Science degree.

The recommended course of study includes both the education in science and mathematics, as well as introduction to the special skills that are needed to enter the rapidly expanding and changing field of biotechnology. In addition to the required courses, students may select from a variety of specialized elective science courses to help develop a particular area of interest. Students majoring in biotechnology are required to perform a research project in the laboratory of a faculty advisor. The results of the research project are incorporated into a senior thesis and presented at the Biotechnology Seminar.

Biotechnology students must maintain at least a 2.5 overall grade point average (GPA) after 60 credits in order to remain in the program.

A faculty advisor is assigned to each student to assist in scheduling, registration and career development. Faculty in each of the cooperating life-science departments have been identified to serve as academic and research advisors for students who select the biotechnology major. The faculty advisor and the director of the biotechnology program regularly review the progress of each student.

The faculty who advise, teach and serve as research mentors for the biotechnology program are spread among several academic departments in the College of Agriculture, Food Systems, and Natural Resources, the College of Science and Mathematics and the College of Health Professions. The departments include plant sciences; biological sciences, biology, botany and zoology; chemistry, biochemistry and molecular biology; animal and range sciences; plant pathology; veterinary and microbiological sciences; and pharmaceutical sciences. Several scientists at the NDSU Center for Nanoscale Science and Engineering and at the on-campus USDA facilities also serve as research mentors.

Laboratory facilities and specialized equipment are used for instruction and research. These include animal and plant tissue culture facilities, small animal housing, electron and confocal microscopes, automated DNA sequencing equipment, equipment for performing microarray experiments, and NDSU Core Labs. The Core Labs are shared cutting-edge research facilities and include the Advanced Imaging and Microscopy Core, Core Biology Facility, Core Synthesis and Analytical Services and the Electron Microscopy Core Laboratory, among many other state-of-the-art facilities and equipment.

Biotechnology continues to rapidly develop into new research areas. Surveys indicate there will be a continuing high demand for well-educated personnel. Job opportunities are found in life science departments in colleges and universities; private and government research institutes; food production, pharmaceutical and agri-chemical industries; and in the biotechnology industries. Graduates of this program have the educational background and laboratory experience to take advantage of any of these job opportunities. Graduates of the biotechnology program are now successful and productive scientists at pharmaceutical, agri-chemical and biotechnology companies, and at government and private research institutions throughout the country.

The majority (approximately 60 percent) of graduates from the biotechnology program choose to continue their education in graduate or professional schools. Graduates of the biotechnology program have earned masters and doctoral degrees in many diverse areas, including cellular and molecular biology, biology, microbiology, plant sciences, animal physiology, cancer biology and virology at many of the most respected universities in the United States. Graduates of our program are now established and productive professors, physicians and veterinarians.

Students entering the biotechnology program should have a strong background in mathematics, including trigonometry, biology, chemistry, preferably physics, writing and computer courses. A composite ACT score of 26 or higher is recommended.

4

This sample curriculum is not intended to serve as a curriculum guide for current students, but rather an example of course offerings for prospective students. For the curriculum requirements in effect at the time of entrance into a program, consult with an academic advisor or with the Office of Registration and Records.

Van Es Hall Lab 160

Van Es Hall is located on the west side of campus on Centennial Boulevard (Campus Map)

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