StemCell Therapy

It was negative three degrees outside when Evi Dixon remarked on what a beautiful day it was. Originally from Austria, she is no stranger to a white world and chilly temperatures. Actually, snow is what initially brought her to Big Sky the plan was to work one season abroad as a ski instructor. Instead of returning immediately, she met a fella and had two children. They all moved back to Austria, but her ex husband missed home and returned to Montana.

She described Big Sky as a tiny, deserted little place in the early days, particularly in the summer and fall no one was around. Twelve years later, Dixon returned to a different Big Sky, a thriving mountain, and she would meet a new man. For years, she worked on the mountain in the ski school office, at BASE Camp when it was just starting, she became an EMT, a ski patroller and eventually an accident investigation supervisor for ski patrol, where she would take pictures and measurements, find witnesses and record the data. Dixon also did avalanche patrol, became a dispatcher and eventually trained dispatchers, a job she describes as one people rarely want, but that is important.

She believes she was the oldest woman to ever start professionally patrolling at Big Sky Resort.

A rough divorce in 2015 led her to another path, but first through a gauntlet of pain.

I gave myself up completely to [my marriage], she said softly with her slight accent. I was at the bottom of my energy. I had to do something. I couldnt wait any longer because I was really thinking of ending my life. I needed to do something so I started my own business.

From there, she said she found meaning and not just from a feeling of purpose, but also from positive interactions with new people, working on her personal development, her mindset.

It gave me so much hope. I really love it. Theres always a reason or a silver lining behind what happens, she said. Im here. Im happy. It still hurts what happened. That was really awful. I try to look to my future and get my feet on the ground. In Austria, she was a therapist. So after her divorce, she returned to her roots. Helping people makes her happy.

In Austria, she studied kinesiology and became a craniosacral therapist. Her focus is in frequency medicine. What some people may define as Eastern Medicine she refers to as integrative. She believes the eastern and western ways of medicine can work together and create the best possible outcomes for patients.

Her home business now involves the Healy, a device created by a German physicist and engineer who was a monk in India for 20 years. He created a handheld device that has similar capabilities as a large machine. With a team of doctors behind it, Dixon explained that it has applications for things like pain management, sleep, concentration, meridians, chakras, the whole gamut.

I can scan peoples biodynamics and their electric fields. It tells me what frequency people need and then it sends out the frequencies through the electromagnetic or biodynamic field, since we are all energy, we are all biodynamic, we are all frequency, every piece of music, every tree we are all connected, she said. She can treat people in Australia or India and has even treated animals.

Whatever Dixon decides to pursue she does with determination and a willingness to learn. A few years ago, she wanted to find animals to keep the grass mowed down on her property. After settling on alpacas and launching her business Spanish Peaks Alpacas, she learned to shear them and now travels around to other farms to help with shearing. From there, she learned how to spin yarn, how to knit and weave.

In many ways, she is the consummate entrepreneur, allowing for one pursuit to lead her to another and into a further understanding of entire industries. She continues to diversify her portfolio.

Dixon even recently became an author of an ebook titled, Activate Your Inner Healer, that contains 10 tips for self healing.

Life has never really been easy on her, she said. Her challenges started when she lost her parents as a little girl.

We are all going through trauma, but I still believe that Im a lucky person, she said.

When difficulties stack and she begins feeling overwhelmed, she does what she can to get herself recentered.

Meditate, go out and hug a tree, go listen to inspirational videos, go and dance. Or if its time to cry, its time to cry, she said. The main thing is that we have stories that happen and we have to understand the things that happen they are not happening to us, they are happening for us. That is a little bit of difference in the wording, but it is a big difference in the meaning. Life goes on and we have to deal with it. We are just going to become stronger.

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Report Ocean recently published Nutrigenomics Market report which highlights the important factors that are expected to shape the growth of the Nutrigenomics Market over the forecast period. The current trends, market drivers, opportunities, and restraints are thoroughly evaluated to provide a clear understanding of the current market landscape of the Nutrigenomics Market. Technological innovation and advancement will further optimize the performance of the product, making it more widely used in downstream applications. Moreover, Porters Five Forces Analysis (potential entrants, suppliers, substitutes, buyers, industry competitors) provides crucial information for knowing the Nutrigenomics Market.

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Competitive Landscape:Key players in the global Nutrigenomics market covered in Chapter 4:DSM N.V.XCODE Life Sciences Pvt. Ltd.Nutrigenomics New ZealandBASF SENutrigenomixMetagenics, IncDNALIFEGenomix Nutrition, Inc.Cura Integrative MedicineNutraGeneWellGen Inc.DanoneGX Sciences

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Comprehensive Report on Nutrigenomics Market by global COVID-19 impact analysis, industry trends, business strategies, opportunities and forecast to...

TORONTO, Oct. 07, 2020 (GLOBE NEWSWIRE) -- CB2 Insights (CSE:CBII; OTCQB: CBIIF) (CB2 or the Company), one of the largest integrative healthcare systems in the United States, is pleased to announce that it has completed the asset acquisition of Maverick County Medical (MCM) in Eagle Pass, Texas. The acquisition of MCM expands the Companys bricks and mortar and telemedicine services to 14 States and adds 10,300 new patients to its current roster of 100,000.

MCM has been operating in Eagle Pass for over 15 years with strong patient retention. Services to patients include primary care, occupational medicine, disease management, minor surgeries, and treatment for auto accident injuries, among others. Services provided by MCM are primarily reimbursed through insurance carriers including Medicare, Medicaid and other commercial payors. MCM also provides services for un-insured patients however representing a smaller proportion of todays revenues.

The Company expects to see continued growth in patient registrations and visits as MCM continues to thrive among the challenges most clinics have faced due to the recent COVID-19 pandemic. Further, the Company will work quickly to expand on the current offering of services by leveraging its current telemedicine infrastructure to provide access to patients across the state of Texas. The Company will also evaluate the current services offered to determine growth in new and complimentary services, add new lines of revenue from insurable services, and expand overall patient care.

Our goal is to provide accessible and affordable healthcare solutions, said Prad Sekar, CEO, CB2 Insights. With the expansion into Texas by way of acquisition of MCM, we welcome a family of practitioners, staff and doctors who align with the direction of our Company, and will be a central point of expansion for our services through telemedicine, subscription services for uninsured patients, and the vision for an integrated National healthcare network.

MCM represents the first acquisition by the Company since its recently announced oversubscribed private placement of CAD 5.13 million in September 2020. The acquisition is also part of a 3-pronged growth model which includes growth from the current infrastructure, new services and acquisitions. The Companys experienced management team continues to develop a robust pipeline of accretive and strategic acquisition targets that are revenue generating, profitable and offer significant opportunities for growth.

The Company paid a total cash consideration of CAD 0.98 million for MCM. Terms of the transaction include a customary transition by the previous owners with 50% of the cash awarded at the signing of the transaction, and 50% due 6 months from the date of completion of the transaction. MCM reported revenues in 2019 of CAD 1.6 million and net income of CAD 0.29 million.

About CB2 Insights

CB2 Insights (CSE:CBII OTCQB:CBIIF) is a healthcare services and technology company, working to positively impact patient health outcomes. The Companies mission to improve the lives of patients through the prevention and treatment of health conditions and using proprietary technology to monitor, assess, and generate insights to help improve patient outcomes. The Company owns and operates a proprietary virtual telehealth platform, and a network of over 30 medical clinics across 13 states in the US, providing integrative, primary and urgent care services to over 100,000 patients annually.

The Company has created works primarily to roster and treat patients seeking traditional and alternative treatments due to the ineffectiveness of conventional medicine, inability to find support through their existing care network, or in some cases, inability to access a primary care network. The Company offers both primary care via a traditional insurable services model and a disruptive low-cost subscription based urgent care offering for patients seeking immediate need to a healthcare provider via telehealth.

The Company differentiates itself by being one of the largest integrative medical practices in the US that owns its own proprietary technology, data analytical assets, and clinical research expertise to support new market expansion, market access, data collection and analysis and drug discovery.

The Company operates a proprietary electronic health record platform Sail (Sail) to document, treat, monitor and report on patient health outcomes. Developed in 2015, Sail is used internally across all of the Companys clinical operations. Sail features a robust telemedicine platform that the Company uses to provide care to its National patient base. To support patient care and positive health outcomes, the Company is also focused on advancing safety and efficacy research surrounding alternative health treatments by monitoring and assessing Real-World Data (RWD) and providing Real-World Evidence (RWE) through our proprietary technology, data analytics, and a full service contract research organization.

For more information please visit http://www.cb2insights.com or contact:

Investor RelationsJonathan L. Robinson CFAOak Hill Financialjrobinson@oakhillfinancial.ca416-669-1001

Forward Looking Statements

Statements in this news release that are forward-looking statements are subject to various risks and uncertainties concerning the specific factors disclosed here and elsewhere in CB2s filings with Canadian securities regulators. When used in this news release, words such as "will, could, plan, estimate, expect, intend, may, potential, believe, should," and similar expressions, are forward-looking statements.

Forward-looking statements may include, without limitation, statements regarding the Companys unaudited financial results and projected growth.

Although CB2 has attempted to identify important factors that could cause actual results, performance or achievements to differ materially from those contained in the forward-looking statements, there can be other factors that cause results, performance or achievements not to be as anticipated, estimated or intended, including, but not limited to: dependence on obtaining regulatory approvals; investing in target companies or projects which have limited or no operating history and are subject to inconsistent legislation and regulation; change in laws; reliance on management; requirements for additional financing; competition; hindering market growth and state adoption due to inconsistent public opinion and perception of the medical-use and recreational-use marijuana industry and; regulatory or political change.

There can be no assurance that such information will prove to be accurate or that management's expectations or estimates of future developments, circumstances or results will materialize. As a result of these risks and uncertainties, the results or events predicted in these forward-looking statements may differ materially from actual results or events.

Accordingly, readers should not place undue reliance on forward-looking statements. The forward-looking statements in this news release are made as of the date of this release. CB2 disclaims any intention or obligation to update or revise such information, except as required by applicable law, and CB2 does not assume any liability for disclosure relating to any other company mentioned herein.

No securities regulator or exchange has reviewed, approved, disapproved, or accepts responsibility for the content of this news release.

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CB2 Insights Announces Acquisition of Texas-based Primary Care Medical & Wellness Clinic with $1.6 million in Revenue and Positive EBITDA -...

For as long as humans have existed, they have told stories to each other. But what about the stories people tell themselves? A breakthrough documentary, Is Your Story Making You Sick? offers a compelling look at how stories define how people see themselves, view relationships, live their lives and manage their health.

Dr. Uday Jani, a respected Milton internist who specializes in integrative medicine, and Lewes chiropractor Dr. Krista Griffin invite the community to watch this award-winning film. An outdoor screening will be held at 7 p.m., Thursday, Oct. 15, at Leftys Alley & Eats, 36450 Plaza Blvd., Lewes. Other screenings set to be held Oct. 8 and 10 in Leftys banquet room are being reworkeddue to changing COVID conditions in the community. A Zoom webinar is being planned; check Dr. Janis website at udayjanimd.com for details on how to participate.

The film features eight people from all walks of life who bravely confront their stories, along with top national mental health experts and a revealing look at narrative therapy exercises and modalities.

This is an important film showing an innovative approach to healing through the real-life journeys of people living with addiction, trauma, depression and anxiety who learn how to confront and ultimately change their stories, said Jani. In this time of COVID anxiety, loneliness and isolation, the baggage people carry may seem heavier than before. But as this documentary shows, there are many tremendously effective modalities that can start the healing.

Jani, who utilizes mind-body practices to care for his patients, credits his fellowship studies at the Arizona Center for Integrative Medicine, and particularly his mentor there, Dr. Ann Marie Chiasson, who appears in the documentary.

It is possible to overcome addiction, PTSD, depression and other stress-related illnesses by re-examining the stories we tell ourselves, said Jani. Finding whats at the root of each individual patients story is how you begin to rewrite the story and begin the process of transcending pain.

The documentary expertly weaves years of filming and research, intensive narrative group therapy, and expertise from leaders in the fields of trauma, addiction, and mindfulness to illustrate the road to meaningful change.

The story problem can manifest in many different ways, and frequently results in a variety of incorrect diagnoses and unneeded drug treatments, said Jani. Learning how to monitor and modify patterns that trigger symptoms allows new patterns to be created and a new story to evolve. The power of healing mind, body and spirit with community involvement has become even more essential during this time of COVID.

Griffin said, Everyone should see this movie. It demonstrates the power childhood emotional traumas have over choices throughout ones life. The message of resilience and overcoming is beautifully encouraging and hopeful.

We so appreciate the swift and enthusiastic participation of Leftys owner DJ Hill, who has graciously made his facility available to the community for viewing this important film, said Jani. He has ensured every protocol, from mask wearing to social distancing, is scrupulously followed to keep us all safe.

The film screenings include a live Q&A immediately following the documentary, with Jani and Griffin joined by integrative health specialist Dr. Carolyn Trasko and clinical psychologist Dr. Richard Todd. Proceeds from ticket sales will benefit the Harry K Foundation, dedicated to defeating childhood hunger in Delaware.

For a preview, watch the trailer at youtu.be/zOpUK50JN1g.

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Jani and Griffin to host outdoor documentary screening Oct. 15 at Lefty's - CapeGazette.com

What Is a Holistic Veterinarian, and How to Find the Right One for Your Pet?

These experts are trained in natural remedies such as food, herbal medicine, and acupuncture.

Natural remedies such as food, herbal medicine, and acupuncture aren't just for humans. They are treatments for your dog, cat, or guinea pig, too, and they come from a holistic veterinarian, who uses a combination or conventional medicine and natural remedies to treat your pets' ailments.

But holistic veterinarians do more than use natural remedies. "A holistic veterinarian is looking at the pet as a whole, where everything is connected, versus just treating symptoms," explains holistic veterinarian Dr. Katie Woodley, DVM. They're concerned with sousing out the root cause of a problem, she says, and then treating that underlying issuenot just reducing its symptoms. For example, if your pet has an allergy, a conventional veterinarian might treat the problem with steroids, but the problem could return as soon as steroids are no longer administered, Dr. Woodley says. But a holistic veterinarian would look for the root cause of the allergic reactionsuch food or environmentand seek to resolve the issue in a way that does not come back, she says.

Anna Avdeeva / Getty Images

There's nothing wrong with conventional medicine, of course. Both conventional and holistic "methods have their strengths and weaknesses," says Dr. Gary Richter, DVM, owner of Montclair Veterinary Care and Rover health expert, who practices integrative medicine, which is a combination of both methods.

Related: Try One of These Alternative Treatments for Your Pet's Holistic Health

Both conventional and holistic veterinarians receive the same conventional medicine training, but holistic veterinarians further their education through the study of practices such as food therapy, herbal medicine, acupuncture, homeopathy, aromatherapy, and more, Dr. Woodley explains. Pet parents might seek a holistic veterinarian for a number of reasons, Dr. Richter says: They might prefer a holistic philosophy for their own healthcare, and want their pet to experience the same. Or, he says, they've tried conventional medicine and haven't seen the results they ideally want. A pet that's in pain, for example, may not improve with medicationbut a holistic veterinarian could try acupuncture, supplements, or herbal medicine to aid other medications, Dr. Woodley says.

Other unique treatments and services holistic veterinarians may offer could include chiropractic care, ozone therapy, or homotoxicology, says Dr. Richter, who adds that "some [treatments] are more scientifically based than others and what specific therapies are offered by a holistic veterinarian varies greatly based on their education, experience, and personal philosophy."

To find the best holistic veterinarian for youand for your pet's needsDr. Richter recommends going to the American Holistic Veterinary Medical Association's website, where you can search for holistic veterinarians in their area. There, you'll also be able to see what unique certifications a veterinarian hasso, for example, if you think your pet needs acupuncture, you can filter the results to find holistic veterinarians that provide acupuncture service in your area, Dr. Woodley says. It's always smart to check reviews too, she adds, "to see if other people have found them helpful for the care of their pet." Perusing their website and social media might help you get a sense of their philosophy, she says, and help you to determine "if it resonates with you as a pet parent."

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What Is a Holistic Veterinarian, and How to Find the Right One for Your Pet? - Yahoo Lifestyle

While it may seem like ginger is a recent trend in holistic and alternative treatments, the plant, which originated in Southeast Asia, has been used for medicinal purposes in countries like India and China for centuries. In fact, many Asian households used it to help treat anything from a headache to a sore throat to menstrual cramps long before studies and scientific evidence proved gingers health benefits.

Healthy Brain Foods You Should Be Eating

According to a study discussing the effectiveness of ginger in the journal Integrative Medicine Insights, the anti-nausea properties of ginger come from gingerols, which are natural anti-inflammatory and antioxidant compounds found in raw ginger that activate spice receptors on the tongue.

If you've ever had ginger ale or ginger tea to settle an upset stomach, you already know that ginger can help with nausea and digestive problems. But to get the largest amount of health benefits from ginger, you should be consuming it raw.

Along with its anti-nausea properties, ginger also stimulates gastric emptying, moving things out of the stomach more quickly and thus providing relief to tummy troubles.

Beyond its use for nausea, ginger is also packed with nutrients that benefit both the body and brain andwhile these healing properties are present in many of its forms, you might consider having a few fresh ginger roots on hand.

In 2013, researchers studied the antiviral effects of both fresh and dried ginger on a respiratory virus in human cells. The study indicated that fresh ginger was an effective tool in protecting the respiratory system, while the dried ginger was not.

Raw ginger is a low-cost and easy-to-find natural remedy that you can use to help treat several everyday issues like sore throats and headaches. If youre unsure how to consume raw ginger, there are a few different ways.

The first is to mince raw ginger and blend it up in a healthy fruit smoothie. To lessen the zing, use fruits that have a lot of sweet flavor like fresh mangos. In this recipe for a mango smoothie with turmeric green tea and ginger, matcha powder adds a soft earthiness that tones down the sharp ginger.

Another option is to add a chunk of ginger to a hot cup of tea or hot water. You dont even have to peel it simply place a piece of ginger in your teacup and pour boiling water over it. Add some honey and a squirt of fresh lemon if you like, and youve got the perfect remedy for fall sniffles.

You can also grate some ginger into your favorite comforting or spicy soup. When you grate ginger as opposed to dropping it in raw, the result is milder and much more dispersed. Its a staple in Indian cooking and brings both heat and a slightly spicy, slightly sweet flavor.

If youre more of an amateur baker, you can also add chopped pieces of ginger to muffins or cake batter or try pumpkin desserts with fresh ginger for a zesty fall twist.

But if you dont want to whip up a recipe, you can eat it raw just as is you only need a tiny sliver to chew on. Cut an inch off the ginger root, use a spoon to peel the brown skin off and nibble on it. You can also use a vegetable peeler to shred super thin slices of ginger and let them sit on your tongue before chewing them down for a less pungent experience.

If youre not familiar with storing raw ginger, it can last in the fridge for three to four weeks and even longer in the freezer. Simply place the root in the vegetable drawer or in an eco-friendly produce bag to keep it fresh, and when youre ready to use it, you can use a grater or zester to grate the frozen piece of ginger right in without needing to thaw it.

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What Are the Good Benefits of Ginger? - The Daily Meal

Newswise Irvine, Calif. September 30, 2020 In a new study, published in Current Biology, researchers from the University of California, Irvine School of Medicine reveal how subanesthetic ketamine, which is used for pain management and as an antidepressant in humans, is effective in treating adult amblyopia, a brain disorder commonly known as lazy eye.

Our study, demonstrates how a single-dose of subanesthetic ketamine reactivates adult visual cortical plasticity and promotes functional recovery of visual acuity defects resulting from amblyopia, explained Xiangmin Xu, PhD, a professor of anatomy and neurobiology and director of the Center for Neural Circuit Mapping at the UCI School of Medicine.

Subanesthetic ketamine, commonly used to treat depression and pain, evokes rapid and long-lasting antidepressant effects in human patients. There was evidence that ketamine may control how the nervous system makes structural changes in response to internal and external demands, a process called neural plasticity. But, how the drug worked remained elusive, until now.

Our research team showed that ketamine down-regulates NRG1 expression in PV inhibitory cells, resulting in sustained cortical disinhibition to enhance cortical plasticity in adult visual cortex, said Steven F. Grieco, PhD, a postdoctoral scholar in the Xu lab and lead author. Through this neural plasticity-based mechanism, ketamine mediated functional recovery from adult amblyopia. Xin Qiao, PhD, a postdoctoral staff in the Xu lab is a co-first author for the published paper.

Amblyopia is a vision disorder in which the brain fails to process inputs from one eye, favoring the other eye. The condition can result in decreased vision in the affected eye. Each year, between one and five percent of children worldwide, are diagnosed with this condition.

Fast and sustained ketamine actions show promise for therapeutic applications that rely on reactivating adult cortical plasticity. Further testing is needed to determine the full implications of this discovery.

This study was supported in part by grants from the National Institutes of Health.

About the UCI School of Medicine

Each year, the UCI School of Medicine educates more than 400 medical students, and nearly 150 doctoral and masters students. More than 700 residents and fellows are trained at UCI Medical Center and affiliated institutions. The School of Medicine offers an MD; a dual MD/PhD medical scientist training program; and PhDs and masters degrees in anatomy and neurobiology, biomedical sciences, genetic counseling, epidemiology, environmental health sciences, pathology, pharmacology, physiology and biophysics, and translational sciences. Medical students also may pursue an MD/MBA, an MD/masters in public health, or an MD/masters degree through one of three mission-based programs: the Health Education to Advance Leaders in Integrative Medicine (HEAL-IM), the Leadership Education to Advance Diversity-African, Black and Caribbean (LEAD-ABC), and the Program in Medical Education for the Latino Community (PRIME-LC). The UCI School of Medicine is accredited by the Liaison Committee on Medical Accreditation and ranks among the top 50 nationwide for research. For more information, visit som.uci.edu.

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New study finds antidepressant drug effective in treating lazy eye in adults - Newswise

"The mind and the body are so intertwined," Fulop says. "If a person is dealing with the constant stresses of daily life it is likely to manifest in physical aches and pains in the body." To break it down: When the brain releases stress hormones, triggering the fight-or-flight response, heart rate and blood pressure can increase. When these two vitals go up, Fulop says the muscles will tighten.

"When muscles will stay in a contracted state and shorten, pain will eventually set in," she says. "How we treat our body through our eating habits, exercise habits, and dealing with stress will play an extremely important role in our overall health and wellness."

On top ofthat, living with chronic pain will begin to change how the body processes pain over time, Nerurkar says. "And long-standing chronic pain can have an impact on the mind-body connection." Managing these symptoms before they become chronic can increase the overall quality of life.

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Clenched Teeth? How That Tension Might Affect The Rest Of The Body - mindbodygreen.com

A Vanderbilt team of experts in virology, genetics, structural biology, chemistry, physiology, medicine, immunology and pharmacology have together developed technology to understand and predict animal susceptibility to SARS-CoV-2, the scientific name for the strain of coronavirus causing COVID-19. providing evidence that horses and camels may be at increased risk of the virus. The group has also released a publicly available tool to enable people to understand the likelihood of other animals susceptibility.

The article, Predicting susceptibility to SARS-CoV-2 infection based on structural differences in ACE2 across species, was published in the Federation of American Societies for Experimental Biology (FASEB) Journal on Oct. 5.

The investigators applied a combination of sophisticated genetic sequence alignment and structural analysis of ACE2, the receptor protein for SARS-CoV-2, to a variety of known susceptible and non-susceptible species. Through the analysis they identified five particular amino acid sites within the protein that distinguish virus susceptibility or resistance, and using these sites developed an algorithm to predict susceptibility of unknown species. The algorithm has been made public on a website where people can upload the aligned ACE2 sequence of animals with unknown susceptibility to generate a COVID-19 susceptibility score.

Jacquelyn Brown, a staff scientist at the Vanderbilt Institute for Integrative Biosystems Research and Education, initiated the project. When I first learned that COVID-19 had crossed the species barrier into cats and dogs, I became worried about other animals that might act as reservoirs for the disease or be at risk, explained Brown, an avid equestrian who practices medieval mounted archery. Since MERS infects camels, I was concerned about what would happen if my horse could get it?! Horses have massive lungs and a sensitive respiratory system, and we humans often touch their noses and mouths.

206,000 horses live on horse farms and properties in Tennessee and 3.2 million of the states 10 million farm acres are devoted to the horse industry. Brown proposed a collaborative research project on the topic to Gordon A. Cain University Professor John Wikswo, who holds appointments in physics, biomedical engineering, and molecular physiology and biophysics.

As the director of VIIBRE, an institute established to foster and enhance interdisciplinary research in the biophysical sciences, bioengineering and medicine at Vanderbilt, Wikswo immediately assembled a trans-institutional team spanning Vanderbilt schools and colleges and Vanderbilt University Medical Center. I speak each disciplines language well enough to make the necessary connections, Wikswo said. This proved to be an outstanding group brought together by their interests and skills that produced an important result in very short order.

The project gave meaning to each researcher, at a time when we all were searching for ways to contribute to fighting COVID-19, noted Wenbiao Chen.

The work could not have been achieved without the collaboration of many researchers. The multidisciplinary approach revealed how much information can be wrung from the same basic information, noted Wenbiao Chen, the papers co-corresponding author and associate professor of molecular physiology and biophysics. We found potential targets by sequence comparison but wouldnt have been able to interpret our findings without structural information. The project gave meaning to each researcher, at a time when we all were searching for ways to contribute to fighting COVID-19.

Understanding the animals we should more closely scrutinize based on their susceptibility to COVID-19 can help us protect people, pets, wildlife, livestock and our food sources, said Matthew Alexander, assistant professor of medicine. The algorithm the team developed is particular to SARS-CoV-2 because it focuses on its particular receptor binding protein ACE2, but the approach is broadly applicable to predicting susceptibility to other viruses or during future outbreaks.

There is also the opportunity to investigate if the identified five sites on ACE2 that most distinguish susceptible from non-susceptible species can be used as targets to develop drugs that inhibit these sites specifically. I hope that our results will inspire future research on both rational drug design and closer examination of at-risk species, said Meena Madhur, the papers co-corresponding author, associate professor of medicine and associate director of the Vanderbilt Institute for Infection, Immunology and Inflammation at VUMC.

Of note, the work and collaboration were conducted remotely, with an analysis of publicly available data. This experimental approach of using extensive and rapidly accumulating publicly available data in new ways allowed us to efficiently answer a timely question without having to generate new datasets. The collaboration was fun and rewarding, and we were able to answer an important question that none of us could have solved alone, Alexander, the papers co-first author said. Wikswo pointed out that while the source data was public, the project required massive calculations of how different versions of the virus would bind to each animals ACE2.

Members of the collaborative project also include Distinguished Research Professor of Chemistry Jens Meiler, Clara Schoeder, co-first author and postdoctoral scholar, , Charles Duncan Smart, graduate student in molecular physiology and biophysics, Chris Moth, computational chemist in the biological sciences department, and Tony Capra, research associate professor of biological sciences.

The work was supported by National Institutes of Health grants F32HL144048-01, DK117147, UH3TR002097 and U01TR002383, U19AI117905, U01AI150739, and R01AI141661, R35GM127087, and DP2HL137166 and American Heart Association grants 20PRE35080177 and EIA34480023

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Vanderbilt researchers develop publicly available COVID-19 animal susceptibility prediction tool; suggests increased risk to horses - Vanderbilt...

Most mornings can benefit from a cup of coffee, but that doesn't mean every morning should start with a cup of coffee.

"Something that's become a big game-changer for me is starting the morning off with two large glasses of water," Bulsiewicz says. "I have not given up coffee. I will not give up coffee. I've just found that my body responds better when I reach for water first."

Think about it. To avoid waking up in the middle of the night to pee, urologist Vannita Simma-Chiang, M.D., recommends taking a final sip of water about three hours before bed. If people follow that rule, by the time they wake up, about 11 hours will have passed without any source of hydration.

"Your body needs that water to start working properly," Bulsiewicz says. "My brain, my gut, and my kidneys all seem to function better when I start with water instead of coffee."

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Cold Water Therapy & Hot Coffee: A GI Doc Shares His Morning Routine Essentials - mindbodygreen.com

Joseph Duffy PhD brings 20+ years of small molecule discovery chemistry and operations to his role as SVP Chemistry of Skyhawk Therapeutics, Elliot Ehrich MD brings 20+ years of clinical development for novel pharmaceuticals to his role as Chief Medical Officer of Skyhawk Therapeutics,and Rob Hershberg MD-PhD with 25+ years of biotech and pharma experience has joined Skyhawk's Scientific Advisory Board.

WALTHAM, Mass., Oct. 5, 2020 /PRNewswire/ -- Skyhawk Therapeutics today announced that Dr. Elliot Ehrich has joined the Company as Chief Medical Officer and Dr. Joseph Duffy has joined as Senior Vice President of Chemistry. The Company also strengthened its Scientific Advisory Board with the addition of Dr. Rob Hershberg.

"We are delighted that Joe and Elliot have come on board at Skyhawk," said Bill Haney, co-founder and CEO of Skyhawk Therapeutics. "Their combined scientific and clinical accomplishments will be invaluable in shepherding our novel RNA-targeting small molecule drug candidates successfully into the clinic. We are also excited to welcome Rob to our Scientific Advisory Board. His clinical and scientific insight and deep experience as a drug developer will be a tremendous addition to Skyhawk."

Elliot Ehrich, MD most recently served as a Venture Partner at 5AM Ventures and Chief Medical Officer (CMO) at Expansion Therapeutics, a 5AM Ventures portfolio company. Previously, Dr. Ehrich spent 17 years at Alkermes ultimately as Executive Vice President of R&D and CMO. At Alkermes he led the development and successful FDA registration of multiple new medicines. Dr. Ehrich has also worked in clinical pharmacology and clinical research at Merck &Co, Inc..

Dr. Ehrich received a BA in biochemistry from Princeton University and an MD from Columbia University. He completed a residency in internal medicine and a fellowship in immunology and rheumatology at Stanford University Medical School followed by postdoctoral research the Department of Microbiology and Immunology.

Over the past four years, Joseph Duffy PhD, served as Executive Director of Discovery Chemistry atMerckResearch Laboratories in Rahway and Kenilworth, New Jersey, where he oversaw multiple preclinical drug discovery teams. Dr. Duffy's contributions over 24 years at Merck included all phases of drug discovery, from lead identification through clinical phase candidate development. He directed successful lead optimization efforts for multiple indications, resulting in clinical candidates and Investigational New Drug (IND) applications from both internal projects and international collaborative research with biotech organizations. Dr. Duffy received his B.Sc. in Chemistry from Kent State University and his Ph.D. from Harvard University.

Rob Hershberg MD-PhD began his career as an Assistant Professor at Harvard Medical School and an Associate Physician at Brigham and Women's Hospital in Boston. Later, Dr. Hershberg co-founded VentiRx Pharmaceuticals and, as President and Chief Executive Officer, led the company through its transformational partnership with Celgene. Dr. Hershberg joined Celgene in 2014 to lead their efforts in Immuno-Oncology, was promoted to Chief Scientific Officer in 2016, and was subsequently Executive Vice President and Head of Business Development & Global Alliances and served as a member of the Executive Committee until the acquisition of Celgene by Bristol-Myers Squibb in 2019. Rob is currently a Venture Partner on the Frazier Life Sciences team. He completed his undergraduate and medical degrees at the University of California, Los Angeles and received his Ph.D. at the Salk Institute for Biological Studies.

Dr Hershberg joins Skyhawk's distinguished Scientific Advisory Board which includes:

Skyhawk Therapeutics is committed to discovering, developing and commercializing therapies that use its novel SkySTARTM (Skyhawk Small molecule Therapeutics for Alternative splicing of RNA) platform to build small molecule drugs that bring breakthrough treatments to patients.

For more information visit: http://www.skyhawktx.com, https://twitter.com/Skyhawk_Tx, https://www.linkedin.com/company/skyhawk-therapeutics/

SKYHAWK MEDIA CONTACT:Anne Deconinckanne@skyhawktx.com

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SOURCE Skyhawk Therapeutics

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Skyhawk Therapeutics Expands Leadership Team with Chief Medical Officer and Head of Chemistry, and adds to its Scientific Advisory Board - BioSpace

New Zealand, which will go into elections on October 17, will also be holding a referendum to decide whether cannabis should be legalised or not.

If New Zealanders are to vote for legalising cannabis for recreational usage, it would join the likes of countries such as Canada, Uruguay and certain states in the United States where consumption of marijuana is legal. Early poll numbers, from the latest Newshub Reid-Research poll, however, reveal that only 37.9 per cent population support the proposition.

In India, the investigations into Sushant Singh Rajputs death has thrown open a Pandoras box of drug abuse in Bollywood. The arrest of actor Rhea Chakraborty by the Narcotics Control Bureau (NCB) over the discovery of 59 gms of curated marijuana seized, and the questioning of lead Bollywood actors such as Deepika Padukone over certain WhatsApp chats which referred to maal and hash, has brought back a much-debated topic - that of legalisation of marijuana.

Also known as Weed, Pot or Ganja, Marijuana is the most commonly used illegal drug in the world.

Around 3 crore people use it in India, alone, with Delhi the third-largest cannabis consumer in the world and Mumbai, the 6th largest.

India also grows some of the most sought after varieties of weed in the world the stunning Parvati Valley in Himachal Pradesh is a Hippies paradise, where the hugely popular Malana weed is cultivated. Keralas Idukki Gold is renowned as one of the best strains of weed in Asia.

Ariel view of and from the mountain village of Malana, India. The place lushes with greenery in the summers, but as it is at 10000 ft, conical rooftops are made to stand the snowfalls of the winter. Its famous for its Quality Hashish, 5K

India is no stranger to marijuana, a drug that has been used for thousands of years, dating back as far as 4000 BC. The cannabis plant even finds a mention in the Vedas and is closely associated with Lord Shiva. The drink Bhang or thandai served during Holi is prepared from dried cannabis leaves and milk, with other spices added to it. Bhang is legal in the country and is sold at specific government authorised shops.

Weed also has a connection with Ayurveda, which, while connoted as a toxic substance in Ayurvedic texts, has traditionally been used in medicines. In 2018, the Centre Council for Research in Ayurvedic Sciences in collaboration with Gujarat Ayurved University found that cannabis leaves can be effective in alleviating pain and other symptoms in cancer patients post-chemotherapy and radiation therapy.

Further, research is being conducted to develop cannabis-based drugs for the treatment of pain in illnesses such as epilepsy, anaemia and cancer by Council of Scientific and Industrial Research - Indian Institute of Integrative Medicine (CSIR - IIIM) in collaboration with Bombay Hemp Company (BOHECO), a startup which works with industrial hemp.

So, with such religious and historical connections to it, how can the consumption of marijuana be illegal in India?

The recreational usage of marijuana is illegal in India and is governed under the Narcotic Drugs and Psychotropic Substances Act, 1985. Consumption of marijuana is punishable with a jail term of six months or a fine of Rs 10,000, while illegal production and cultivation can be punished with a jail term of up to 10 years.

However, marijuana was legal in India until 1984. It was in the 1960s that the United States launched an offensive against the drug and a drive to ban it. During the 1961 Convention on Narcotics Drugs, India had even opposed the classification of marijuana as a hard drug.

Bucking under pressure, the Rajiv Gandhi administration passed the NDPS Act in 1985 which criminalised cannabis in its resin and bud form, but allowed the sale of bhang at government-approved shops.

Ironically, several states in the United States have now either legalised marijuana or are considering it. In India, various NGOs and activists have been asking for its legalisation. Their argument is that the criminalisation of marijuana has pushed the drug underground and to onto the hands of criminals who make it more potent and dangerous.

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Arguments favouringlegalising marijuana also say that it could lead to fewer chances of addiction. A study conducted in 1994 by epidemiologistJohn Anthony who surveyed more than 8,000 people about their marijuana usage, discovered that the chances of getting addicted to the drug were 9 per cent. For alcohol, this figure was 15 per cent, for heroin 23 per cent and for nicotine, 32 per cent.

Legalisation will also help villagersin areas like the Parbati Valley and the upper reaches of Kullu and Manali, and Idukki in Kerala whose main source of income comes from cannabis. Currently, with marijuana being illegal, farmers are forced to sell it to drug peddlers at low prices, and have problems with the police. Those for legalising the drug argue that by making the drug legally available, farmers would benefit from a more regulated market.

However, the fact remains that cannabis, when taken recreationally still remains a drug which could have harmful effects on the consumer. While a plant, it contains the mind-altering chemical, delta-9-tetrahydrocannabinol(THC), which is responsible for the intoxication that people who consume it feel.

The plant also has over 400 other chemicals. Researchers from the University of Alberta have identified potentially toxic chemicals in marijuana smoke which could have health effects. In a single puff of cannabis smoke, researchers have isolated around 110 toxic chemicals which may have carcinogenic, mutagenic or teratogenic effects, which could affect the development of the embryo or foetus.

Research conducted in Pittsburgh has also discovered that children of frequent marijuana users have relatively less attention span than their peers. Early marijuana usage has also been linked to a loss in I.Q levels of pre-teens.

Further, The Dunedin Multidisciplinary Health and Development Study conducted in Dunedin, New Zealand has found that people who smoke even one joint a week are prone to developing respiratory illnesses. Occasional smokers who cut down on weed, also had reduced symptoms, while heavy smokers had a persistent cough and wheeze even after cutting down, or quitting completely. This proves that the side effects of smoking weed on heavy smokers may linger for long.

Those who are against the legalisation of weed are also worried that its usage could prove to be a gateway to other, more potent, hard drugs.

Marijuana, if used responsibly, could help those cultivating it and using it. However, with India already grappling with problems of alcoholism, excessive tobacco usage, much more research needs to be carried out to ensure that the risks do not outweigh the potential benefits.

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Hazy road to legalise marijuana: The case for it and risks involved - Yahoo Canada Shine On

Child Care of the Berkshires Inc.staff have returned to the office as of June 15.

The National Alliance on Mental Illness (NAMI) BerkshireCountyhas announced the addition of a Warm Line, 413-445-1136,a phone number that people can call to talk toeither a NAMI BC staff or a community trained volunteer having lived experience with mental health issues, trauma, and/or to assist individuals through a difficult time, such as the COVID-19 pandemic.NAMI Berkshire County will provide support over the phone as well as resources as available. Calls will be accepted during the day and evening until 8 p.m. Callers experiencing isolation, fear, stress can speak to someone so they will not feel as isolated and find some coping strategies that have worked for the operators staffing the phone.If operators are not available callers can leave their phone number and first name and they will be called back within 24 hours or sooner. The information is strictly confidential.

BHS Helpline.People should contact their primary care physician if theyhave concerns. Testing must be authorizedthroughthe primary care. TheBerkshire Health Systems helpline can answer many questions regarding findinga primary care, testing, or other health related issues.The Nurse Triage line has reduced its hours to 8 a.m. to 6 p.m. daily, still available seven days a week. The number remains 855-BMC-LINK, or 855-262-5465.

Northern Berkshire Adult Education has gone virtual!All classes are offered online, even the PCA class. Free to all adult learners. Brush up your skills to get your GED or to prepare to return to college from the comfort of your home. Contact Bob or AnnaMaria at 413-662-5330 or 413-662-5386.

nbCC Changes to Open Hours and Programs-The Northern Berkshire Community Coalition (nbCC), in an effort to help combat the spread of COVID-19, has made the following changes to open hours and programs:

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nbCC E-Zine - Oct. 1, 2020 - News and Events in Northern Berkshire - iBerkshires.com

Frances Jean Beebe, 78, of West Monroe, passed away Sept. 22, 2020. Funeral services were at 10 a.m. Friday, Sept. 25, 2020, at Apostolic Restoration Church in West Monroe. Interment was in Kilpatricks Serenity Gardens in West Monroe, under the direction of Mulhearn Funeral Home in West Monroe.

Mrs. Adrienne Delery Day, 82, of Monroe, passed away Wednesday, Sept. 23, 2020. Funeral services were at 10 a.m. Saturday, Sept. 26, 2020, at Mulhearn Funeral Home, Monroe. Interment was at Mulhearn Memorial Park Cemetery in Monroe. Visitation was 5-7 p.m. Friday, Sept. 25, 2020, at the funeral home.

Funeral service for Marc Felts, 55, of West Monroe, will be at 2 p.m. Friday, Oct. 2, 2020, at First West, West Monroe. Interment will follow at Roselawn Memorial Gardens, Calhoun, under the direction of Griffin Funeral Home, West Monroe. Visitation is 5-8 p.m. Thursday, Oct. 1, at the funeral hoe, and from noon until time of service Friday at the church. He passed away Monday, Sept. 28, 2020.

Mr. Alex John George, 88, of Monroe, passed away Sept. 21, 2020. Funeral services were at 10 a.m. Tuesday, Sept. 29. 2020 at Sts. Constantine & Helen Greek Orthodox Church, in Monroe. Interment was at Mulhearn Memorial Park Cemetery in Monroe, under the direction of Mulhearn Funeral Home, Monroe.

Memorial services for Billy Ray Johnson, 69, of West Monroe, will be at 3 p.m. Friday, Sept. 25, 2020, at Griffin Funeral Home, West Monroe. Interment will follow at Carter Cemetery. Visitation is from 1 p.m. until time of service at the funeral home. He passed away Sunday, Sept. 20, 2020.

A celebration of life for Steve Mitchel Netherland, 62, of Farmerville, was at 2 p.m. Saturday, Sept. 25, 2020, at Griffin Funeral Home, West Monroe. Visitation was from 1 p.m. until time of service at the funeral home. He passed away Tuesday, Sept. 22, 2020.

Shonda Lea Carroll Parker

Shonda Lea Parker, a devoted wife, mother and author of Christian herbalist study courses, died Tuesday, Sept. 22, at the age of 53 after battling cancer for several years. She was with her family in Calhoun when she peacefully departed to be with her Lord Jesus Christ.

Shonda was born Oct. 17, 1966 in DeRidder. She grew up in Pitkin under the care of her parents, Shelvia Shelby and Virginia Ginny Carroll, each of whom previously died.

Shonda met her husband, Keith Parker, at Louisiana State University in Shreveport. They married in 1986 and reared seven children in Texas, Ohio, North Carolina, Georgia, and Louisiana.

In the late 1980s, Shonda pursued an interest in integrative medicine and herbal therapies. At the time, American herbalism was mostly associated with New Age movements, but Shonda believed she could help reclaim a Christian view of herbal therapies that had been lost in the 20th Century. For more than 30 years, Shonda shared her faith-based approach to understanding Gods creation and how such knowledge could improve the treatment of the human body. She traveled for speaking engagements at midwifery conferences and wrote four books about herbal therapies, family health and food. Under her Naturally Healthy brand, Shonda developed an exhaustive course in Christian herbalism and formulated a line of herbal medicines as well. Though she focused her career on using herbal therapies to assist healthy living, Shonda encouraged reliance on medical professionals as well as the enjoyment of delicious food and drink items like Dr. Pepper.

In addition to her career as a successful author and businesswoman, Shonda devoted herself to her family and church. Whether aiding her children in their various pursuits or hosting large gatherings, Shonda was passionate about helping other people find satisfaction in their calling or meals. Many people knew Shonda as an enthusiastic hostess through her dinner parties and festal work at large gatherings.

A memorial service will be held Saturday, Oct. 3, at 10:30 a.m. at Church of the Redeemer in West Monroe, 715 Cypress St., West Monroe, Louisiana, 71291. Pastor Steve Wilkins, of Church of the Redeemer, will officiate the service and David Alders, of Nacogdoches, Texas, will deliver the eulogy. Services can be livestreamed at redeemertwincities.org

Shondas remains were cremated and will be spread in Texas.

Shonda is survived by her beloved husband, Keith, her seven children and their spouses: Zachary and his wife, Samantha; Emily and husband, Jonathan, of Fort Worth, Texas; Eryn and husband, Braden; Eliana; Zebediah and wife, Bayley; Samuel; Simon; and eight grandchildren.

Funeral services celebrating the life of Mrs. Margaret Johnson Rhone, 103, of West Monroe, were at 11 a.m. Thursday, Sept. 24, 2020, at Mulhearn Funeral Home, West Monroe, with Rev. Ted Freeland officiating. Interment was in Hasley Cemetery in West Monroe. Visitation was 9-11 a.m. Thursday.

Margaret Johnson Rhone was born on Jan. 11, 1917, in Crockett, Texas, the ninth child of Mary Eldora Harrison Johnson and James E. Johnson. She died in West Monroe, on Sept. 22, 2020, after a long illness. Mrs. Rhone married her childhood sweetheart, Robert Franklin Rhone and they made their home in West Monroe, where he was employed by Brown Paper Mill. While many of their peers were offended by the smoke and cinders from the mill, they considered it their bread and butter. They were blessed by the births of two daughters, Barbara Jean Rhone and Denna Maureen Rhone. When the daughters were aged 13 and 10, they were blessed by the birth of a son, Robert F. Rhone Jr.

Margaret and her family were charter members of Brownville Methodist Church, which later evolved into Asbury United Methodist Church. Her church family was very important to her. She was very talented and could do anything she set her mind to. Mrs. Rhone enjoyed all kinds of crafts, canning and freezing vegetables and fruits. She was always busy. She enjoyed quilting and sewing especially. She sewed all her mothers clothes without benefit of patterns and sewed for her daughters until they started working. She also sewed for a good friend, Mrs. Shirley Works Moore, sewing pretty dresses, and gowns for every season and occasion up until she was 95. Mrs. Rhone was a good cook and enjoyed preparing home-cooked meals. It was a source of pleasure for her to provide a safe haven in her home for recreation and social activity for her children and their friends. The last months of her life were difficult as she was forced to admit she couldnt do what she used to and wanted to do.

When her son entered school, she enrolled in and completed the Louisiana Practical Nursing Course, so shed be prepared for his education should she be required to do so. Luckily that was not required.

Mrs. Rhone is preceded in death by her parents; eight siblings; her husband; her son; and grandson-in-law, Mark Zachry.

Survivors include her daughters, Barbara Jean Rhone, and Denna Maureen Rhone Ballard and husband, Richard; daughter-in-law, Frances Luffey Rhone; granddaughter, Tammy Ballard Zachry; great-granddaughter, Katie Zachry Meredith and husband, Jamie and their sons, Noah, Jonah, Luke, and Levi; great-grandson, Paul Zachry and wife, Lauren and their children, Haylea and Owen.

Pallbearers were Paul Zachry, Jamie Meredith, Joey Gardunio, Alex Gardunio, Rick Ray, and Richard Ballard.

Mrs. Gayla Banks Rogers, 73, of Monroe, passed away Sept. 22, 2020. Funeral services were at 2 p.m. Friday, Sept. 25, 2020, at Mulhearn Funeral Home, Monroe. Interment was in the Old Union Church Cemetery in Grayson, under the direction of Mulhearn Funeral Home, Monroe.

Timothy Corbin Sanderford

Timothy Corbin Sanderford, 62, of West Monroe, passed away Tuesday, Sept. 22, 2020. Arrangements are under the direction of Griffin Funeral Home, West Monroe.

Riley Dale Sanderson, 84, of Calhoun, died on Sept. 24, 2020. Private family graveside services were held on Sunday, Sept. 27, 2020, at Roselawn Memorial Gardens in Calhoun, under the direction of Mulhearn Funeral Home, West Monroe.

Mr. James E. Smith Sr., 80, of Bastrop, passed away Saturday, Sept. 26, 2020. Funeral services were at 3 p.m. Tuesday, Sept. 29, 2020, at Mulhearn Funeral Home, Monroe. Interment was at Mulhearn Memorial Park Cemetery in Monroe.

Memorial service for L.D. Smith, 77, of Monroe, was at 2 p.m. Monday, Sept. 28, 2020, at Rowland Road Baptist Church. Services were under the direction of Griffin Funeral Home, Monroe. L.D. passed away, Friday, Sept. 25, 2020.

Funeral service for Jerry Lynn Taylor , 65, of Calhoun, was at 2 p.m. Monday, Sept. 28, 2020, at Griffin Funeral Home, West Monroe. Interment followed at Cheniere Baptist Church Cemetery. Jerry passed away, Saturday, Sept. 26, 2020.

Funeral services for Justin M. Vallery, 37, of Keller, Texas, were at 2:30 p.m. Saturday, Sept. 26, 2020, at Kilpatrick Funeral Home, West Monroe. Interment was at Kilpatricks Serenity Gardens. Visitation was from noon Saturday until service time.

Mrs. Gail Wheelis, 83, of West Monroe, passed away Sept. 27, 2020. Funeral services were at 2 p.m. Wednesday, Sept. 30, 2020, at Mulhearn Funeral Home in West Monroe. Interment was in Rutledge Cemetery in West Monroe.

Mr. Dan Paul White, 64, of Monroe, passed away Saturday, Sept. 19, 2020. A celebration of life service was at 2 p.m. Saturday, Sept. 26, 2020, at Mulhearn Funeral Home, Monroe. A private family interment followed at Mulhearn Memorial Park Cemetery in Monroe.

Lois Ann Whittington, 81, of Calhoun, LA, died on Sept. 27, 2020. Funeral services were at 11 a.m. Tuesday, Sept. 29, 2020, at New Chapel Hill Baptist Church in West Monroe with Dr. Marty Black officiating. Interment was at New Chapel Hill Baptist Church Cemetery under the direction of Mulhearn Funeral Home, West Monroe.

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Obituaries published on Oct. 1, 2020 | Obituaries - The Franklin Sun

As you age, and as a normal response to just going through life, proteins and organelles in your body get damaged or die. If theyre not cleared out, these damaged particles accumulate in your cells and jam things up. When this happens, your cells cant divide and function normallythis can cause cell death and age-related diseases, contribute to poor tissue and/or organ function, and even become cancerous.

Enter the process called autophagy. During autophagy, the body marks damaged parts of cells, unused proteins, and other junk in the body for removal and clears them out. This is a form of cellular cleansing and, really, the true meaning of a detox. Autophagy also helps deliver nutrients to cells that need them.

Autophagy can dictate not only how well we live but perhaps how long we live, says board-certified integrative neurologist Ilene Ruhoy, M.D., Ph.D. It is a key physiological mechanism that has been conserved throughout evolution for the distinct purpose of allowing the human species to thrive. But when the autophagic mechanisms are overwhelmed or dysfunctional, cells are unable to perform optimally and disease can occur, as well as more rapid aging.

Autophagy is absolutely essential for healthy, functioning cells and if its never kicked on to its full potential, you can get sick. One of the most notable ways these dead proteins accumulate is seen in Alzheimer's disease. Because they are never cleared from the body, dead proteins travel to the brain and get stuck there, causing the characteristic plaques associated with the disease.

Think of it this way: autophagy is like the robot vacuum you have in your house. When things get messy, it kicks on, cleaning up debris and unwanted junk, leaving you with a nice clean slate and preventing a buildup that can lead to a bigger mess down the road.

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The Healthy Aging Benefits Of Autophagy & How To Activate The Cellular Process - mindbodygreen.com

The Jammu-based Indian Institute of Integrative Medicine (IIIM) is undertaking clinical trials of 3-4 formulations for developing a COVID-19 drug, a senior official had said. The IIIM is also in the final stages of validating a new machine-less coronavirus diagnostics kit, as already reported by the PTI, which can help the country scale up COVID-19 testing.

"For Covid-19, we are undergoing clinical trials. In collaboration with Ayush ministry and industry, we are involved in it. Three to four clinical trials are going in different plant species with regard to COVID-19 drugs on 3 to 4 formulations, Director CSIR-Indian Institute of Integrative Medicine (IIIM), Dr D Srinivasa Reddy, told PTI. If they (all the requisite trials) are successful, we can make medicines soon available, Reddy said.

"We are definitely getting closer. So many research groups from across the world are giving their best to find treatment for COVID-19. Discovering new medicines is a very long and costly process, he said. The director said that repurposing already known drugs to treat COVID-19 patients is the best option under the present circumstances.

"Several academic and industry groups across the globe are continuously working. In India, in particular the CSIR (Council of Scientific and Industrial Research) is a frontrunner in this direction, he added.

Dr Reddy, who recently took over as the director of IIIM for the next six years, said the first activity that IIIM undertook under him was testing COVID-19 samples.

"We started testing in the first week of April, in collaboration with Government Medical College (GMC), Jammu. We have completed over 40,000 samples till date, he said. We are in the process of increasing the number of samples tested, he said.

The IIIM is also in the process of developing a new formulation based on Zinc Gluconate and natural Vitamin C coming from Acerola Cherry for boosting immunity, he said. It is in collaborations with a company.

He said that the development processes for Active pharmaceutical ingredients (API)as part of repurposing of drugs is underway and our scientists have made significant progress on this activity and one of the processes has been demonstrated to an industry partner in Jammu.

"We continue to work along these lines and start some new initiatives to address COVID-19 related problems. Our scientists and students rose to the occasion and contributed significantly in a short time, he added.

Dr Reddy said that the IIIM laboratory is a unique place for discovering medicines based on natural products everything is under one roof for plant-based or new chemical entity (NCE)-based drugs. It has got rich biodiversity in the region which is known for medicinal and aromatic plants. It has a diverse scientist pool with expertise and experience from various functions. I see a lot of opportunities here, he added. He said that IIIM can lead programmes of national importance in addition to existing assets and expand compound or natural product extracts library and open it to others research purposes.

The IIIM can develop agricultural technologies and commercial cultivation in the Western Himalayas Kashmir Valley and Ladakh regions, he said. There are high-value medicinal and aromatic plants, (but) they seem to be facing problems in the supply chain, in particular, for the international markets. The IIIM can put more efforts in that direction, he added.

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Institute of Integrative Medicine Conducting Clinical Trials of 3-4 Covid-19 Drug Formulations: Director - Yahoo India News

Western medicine, also known as traditional medicine, is the familiar system in which healthcare providers treat symptoms and diseases using drugs, radiation and/or surgery. Complementary and alternative medicine (CAM) is a term used for medical products and practices that are typically not part of traditional medicine or included in standard medical care. The terms complementary and alternative both refer to treatments like herbal remedies or acupuncture. However, complementary medicine is when these therapies are used along with traditional western medicine practices. Alternative medicine refers to using alternative approaches instead of using traditional western medical approaches. Some practices of CAM include massage therapy, acupuncture, acupressure, Tai Chi, aromatherapy, herbal medicine and chiropractic.

When it comes to CAM, there are four major alternative medical systems that were developed by the National Center for Complementary and Alternative Medicine (NCCAM) in 2000. These four alternative medical systems include:

1. Mind-body interventions: involve using specific techniques to boost the minds capacity to influence bodily function and enhance health (i.e. meditation and yoga)

2. Biologically-based treatment: the use of substances found in nature (i.e. herbs, foods and vitamins)

3. Manipulative and body-based methods: focuses on applying specific treatments to address health issues (i.e. reflexology and chiropractic)

4. Energy therapies: based on the idea that energy fields surround and penetrate the human body (i.e. therapeutic touch and Reiki)

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As you can see from the four major alternative medical systems, CAM is used for physical, mental and spiritual health. In addition, CAM is widely used today and is increasing in popularity. In the United States, complementary and alternative medicine is used by about 38% of adults and 12% of children, according to John Hopkins Medical.

If you are interested in integrating or learning more about CAM, ask your primary care provider if integrated therapy is right for you. You can also ask your primary care provider if they can provide you with recommendations and/or contact your local hospital or medical school as they often keep lists of integrative medicine practitioners in the area.

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A message from the health center: complementary and alternative medicines - The Lion's Roar Newspaper

In recent years, the popularity of aromatherapy has significantly increased, especially after celebrities like "Grey's Anatomy" star Ellen Pompeo and "Sister, Sister" actress Tamera Mowry admitted that essential oils were included in their routines.

As Elizabeth Ko, medical director of the UCLA Health Integrative Medicine Collaborative, explained, essential oils carry the "essence" of the plant, and our smell receptors quickly absorb it.

AROMATHERAPY AND ESSENTIAL OILS

Depending on the plant you're using, the effect is different. Most commonly, they range from having anxiolytic or anti-inflammatory properties to boosting your energy and preventing acne.

It is worth noting that the best way to use essential oils is with a diffuser, which is a device that you have to fill with water and add a couple of drops of your favorite essential oil.

Celebrities like Kerry Washington ("Scandal"), Gwyneth Paltrow ("Shakespeare in Love"), and Jenna Dewan ("Soundtrack") have been open about their use of aromatherapy, so after doing our research, we found some of the best essential oils on the market.

CHAMOMILE

This herb has been consumed for hundreds of years by different cultures as a natural remedy for a variety of health conditions, so it was only natural to have it as an essential oil.

Chamomile oil is recommended for people who want to go to sleep without struggling so much, but it is also a good option for sore muscles and to reduce swelling on the skin.

ORANGE

Since orange oils are extracted from sweet oranges, it is one of the most affordable essential oils on the market. If that wasn't enough, it has an anxiolytic effect on people due to its sweet aroma, making it one of the best essential oils for anxiety.

Apart from that, it can also reduce some symptoms of PTSD. It is one of Ellen Pompeo's favorites ("Grey's Anatomy"), so that should give you a good idea of its benefits.

CINNAMON

While cinnamon is commonly used as a spice to give your food that extra touch of quality, it can also be breathed in as an essential oil to boost your focus, as it can impact the area of your brain that governs alertness.

"Soundtrack" star Jenna Dewan confessed that she boosts her immune system by putting Thieves oil, which combines clove, lemon, cinnamon, eucalyptus, and rosemary essential oils, under her tongue.

LAVENDER

Lavender is one of the best essential oils for sleep on the market as investigations have shown that people wake up more refreshed. Apart from that, it is used in dermatology to heal wounds quickly, ease the consequences of insect bites, and reduce redness.

"Sister, Sister" star Tamera Mowry recommends lavender oils to get rid of "a pesky migraine" due to its anxiolytic effect, so this one is a no-brainer.

YLANG YLANG

Due to its sweet floral scent, ylang ylang essential oil is mostly recommended as a soothing option, especially after investigators found that it helped lower people's heart rate and blood pressure.

If that wasn't good enough, this oil is reported to lift people's moodsand their self-esteem while also helping with inflammation.

TEA TREE

Also known as melaleuca, tea tree oil has antibacterial and antifungal properties, which is probably why Australian aboriginal people used it for wound healing in the past.

Nowadays, it is mostly recommended to prevent and treat acne and to help with your energy levels, but it can also be used to repel bugs.

ROSE

One of the best smelling essential oils out there is rose oil, which is reported to relieve pain, including the unsettling menstrual cramps. Additionally, it has antibacterial and antifungal properties, which makes it an excellent option to prevent fungal and staph infections.

If you are like Ellen Pompeo and don't like too-flowery scents, you can combine rose oils with "a dash" of vetiver or sandalwood to give it "a little earthiness."

The information in this article is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, and images contained on, or available through this NEWS.AMOMAMA.COM is for general information purposes only. NEWS.AMOMAMA.COM does not take responsibility for any action taken as a result of reading this article. Before undertaking any course of treatment please consult with your healthcare provider.

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Best Essential Oils: How to Choose the Proper One and Use the Power of Nature - AmoMama

If your life these days is anything like mine, a pre-pandemic routine that included regular exercise and disciplined eating has probably given way to sedentary evenings on a big chair, binge-watching reruns of your favorite TV series while guzzling chocolate ice cream or mac 'n' cheese.

But let's not beat ourselves up about it. Several doctors I spoke with recently said most of their patients and many of their colleagues are struggling to maintain healthy habits amid the anxiety of the pandemic. "The Quarantine 15" (pounds, that is) is a real phenomenon.

The double challenge of protecting our health, including our immune systems, while battling unhealthy temptations "is a struggle everyone is dealing with," says Dr. David Kilgore, director of the integrative medicine program at the University of California-Irvine.

Well before COVID-19, more than 40% of U.S. adults were obese, which puts them at risk for COVID-19's worst outcomes. But even people accustomed to physical fitness and good nutrition are having trouble breaking the bad habits they've developed over the past five months.

Karen Clark, a resident of Knoxville, Tennessee, discovered competitive rowing later in life, and her multiple weekly workouts burned off any excess calories she consumed. But the pandemic changed everything: She could no longer meet up with her teammates to row and stopped working out at the YMCA.

Suddenly, she was cooped up at home. And, as for many people, that led to a more sedentary lifestyle, chained to the desk, with no meetings outside the house or walks to lunch with colleagues.

"I reverted to comfort food and comfortable routines and watching an awful lot of Netflix and Amazon Prime, just like everybody else," Clark says. "When I gained 10 pounds and I was 25, I just cut out the beer and ice cream for a week. When you gain 12 pounds at 62, it's a long road back."

She started along that road in July, when she stopped buying chips, ice cream and other treats. And in August, she rediscovered the rowing machine in her basement.

But don't worry if you lack Clark's discipline, or a rowing machine. You can still regain some control over your life.

A good way to start is to establish some basic daily routines, since in many cases that's exactly what the pandemic has taken away, says Dr. W. Scott Butsch, director of obesity medicine at the Cleveland Clinic's Bariatric and Metabolic Institute. He recommends you "bookend" your day with physical activity, which can be as simple as a short walk in the morning and a longer one after work.

And, especially if you have kids at home who will be studying remotely this fall, prepare your meals at the beginning of the day, or even the beginning of the week, he says.

If you haven't exercised in a while, "start slow and gradually get yourself up to where you can tolerate an elevated heart rate," says Dr. Leticia Polanco, a family medicine doctor with the South Bay Primary Medical Group, just south of San Diego. If your gym is closed or you can't get together with your regular exercise buddies, there are plenty of ways to get your body moving at home and in your neighborhood, she says.

Go for a walk, a run or a bike ride, if one of those activities appeals to you. Though many jurisdictions across the United States require residents to wear masks when out in public, it may not be necessary and may even be harmful to some people with respiratory conditions while doing strenuous exercise.

"It's clearly hard to exercise with a mask on," says Dr. Yvonne Maldonado, a pediatrician specializing in infectious diseases at Stanford University's School of Medicine. "We go hiking up in the foothills and we take our masks with us and we don't wear them unless somebody starts coming the other way. Then we will put the mask on, and then we take it off and we keep going."

If you prefer to avoid the mask question altogether, think of your house as a cleverly disguised gym. Put on music and dance, or hula-hoop, Polanco suggests. You can also pump iron if you have dumbbells, or find a cable TV station with yoga or other workout programs.

If you search on the internet for "exercise videos," you will find countless workouts for beginners and experienced fitness buffs alike. Try one of the seven-minute workout apps so popular these days. You can download them from Google Play or the Apple Store.

If you miss the camaraderie of exercising with others, virtual fitness groups might seem like a pale substitute, but they can provide motivation and accountability, as well as livestreamed video workouts with like-minded exercisers. One way to find such groups is to search for "virtual fitness community."

Many gyms are also offering live digital fitness classes and physical training sessions, often advertised on their websites.

If group sports is your thing, you may or may not have options, depending on where you live.

In Los Angeles, indoor and outdoor group sports in municipal parks are shut down until further notice. The only sports allowed are tennis and golf.

In Montgomery County, Maryland, the Ron Schell Draft League, a softball league for men 50 and older, will resume play early this month after sitting out the spring season due to COVID-19, says Dave Hyder, the league's commissioner.

But he says it has been difficult to get enough players because of worries about COVID.

"In the senior group, you have quite a lot of people who are in a high-risk category or may have a spouse in a high-risk category, and they don't want to chance playing," says Hyder, 67, who does plan to play.

Players will have to stay at least 6 feet apart and wear masks while off the field. On the field, the catcher is the only player required to wear a mask. That's because masks can steam up glasses or slip, causing impaired vision that could be dangerous to base runners or fielders, Hyder explains.

Whatever form of exercise you choose, remember it won't keep you healthy unless you also reduce consumption of fatty and sugary foods that can raise your risk of chronic diseases such as obesity, diabetes and hypertension all COVID-19 risk factors.

Kim Guess, a dietitian at UC-Berkeley, recommends that people lay in a healthy supply of beans and lentils, whole grains, nuts and seeds, as well as frozen vegetables, tofu, tempeh and canned fish, such as tuna and salmon.

"Start with something really simple," she said. "It could even be a vegetable side dish to go with what they're used to preparing."

Whatever first steps you decide to take, now is a good time to start eating better and moving your body more.

Staying healthy is "so important these days, more than at any other time, because we are fighting this virus which doesn't have a treatment," says the Cleveland Clinic's Butsch. "The treatment is our immune system."

This KHN story first published onCalifornia Healthline, a service of the California Health Care Foundation.

Kaiser Health News (KHN) is a national health policy news service. It is an editorially independent program of the Henry J. Kaiser Family Foundation which is not affiliated with Kaiser Permanente.

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Exercise and diet are more important than ever with COVID at large - Salon

Coronavirus contagion spreads by just talking

Forsythia is a plant that produces fruits called Lian Qiao, which has been used in traditional Chinese medicine (TCM) to help treat various symptoms including fever, nausea, swelling, and sore throat.

There is limited evidence to prove the forsythia's effectiveness. The Chinese Journal of Integrative Medicine suggests that Lian Qiao can be used to treat or prevent Coronavirus. The journal also lists Radix astragali (Huangqi), Radix glycyrrhizae (Gancao), Radix saposhnikoviae (Fangfeng), Rhizoma Atractylodis Macrocephalae (Baizhu) and Lonicerae Japonicae Flos (Jinyinhua) for Coronavirus treatment.

As of now the majority of studies on forsythia's medicinal properties were conducted either in animals or in vitro, performed with microorganisms, cells, or biological molecules outside their normal biological context. That is why there is very little scientific evidence on its effectiveness in humans. But from animal and vitro studies, scientists have found many properties that could help explain some of its benefits in traditional Chinese medicine (TCM).

A 2017 study found that in vitro dried Lian Qiao has shown a potential to combat bacteria such as staphylococcus aureus, Escherichia coli, and streptococcus, while a 2013 research revealed the effects of both forsythia and Japanese honeysuckle on the influenza virus, the researchers found that they both restrain the virus from multiplying and boost immune cell function.

A vitro study, which came in 2010 in the Journal of Medicinal Plant Research, said that the plant, mostly native to eastern Asia, could be effective against H1N1. As per another 2017 study, which was conducted on mice, forsythia has shown promising signs in treating intestinal inflammatory conditions like ulcerative colitis.

Forsythia has been studied in treating certain cancers. In a study published in Molecular Medicine Reports, esophageal cancer cells were put into mice, and researchers found that forsythia inhibited the growth of the cancer cells. But further study is needed to completely understand the effectiveness of this herb.

The Use of Natural Remedy

The name 'forsythia' may sound familiar because it was mentioned in the 2011 movie, "Contagion," which became highly popular during the Coronavirus pandemic. There is no solid proof that forsythia can be useful to treat or cure Coronavirus. But, for its antibacterial, anti-inflammatory, and antiviral properties, the plant is used in traditional Chinese medicine to treat bacterial and viral infections.

As per the experts, the safest and best way to take forsythia is to discuss dosage with an herbal medicine expert, as there is not enough and reliable information to know the side effects of this herb. The Food and Drug Administration (FDA) in the U.S. has not approved forsythia products.

Deborah Ann Ballard, MD, MPH, internal medicine doctor at Duke Integrative Medicine said she does not prescribe forsythia to her patients and does not recommend anyone to take forsythia without consulting a Traditional Chinese Medicine doctor. "Proper use of this or any remedy requires an individualized assessment and approach," she added.

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Can Forsythia Cure Coronavirus? Herb With Antibacterial, Antiviral Properties Is Popular in TCM - International Business Times, Singapore Edition