StemCell Therapy

Not long after announcing a wide-ranging partnership with Microsoft to bring artificial intelligence tools to every desk across its R&D departments, Novartis is now teaming up with Amazons mammoth cloud computing division to overhaul its manufacturing, supply and business operations.

The new multiyear collaboration with Amazon Web Services dovetails with the drugmakers directives to embrace and incorporate digital technology at every point in its product pipeline and value chain.

AWS aims to supply the company with an enterprisewide data analytics platform, including AI and machine learning services, as well as cloud-based Insight Centers that will provide real-time metrics to Novartis global technical operations staff.

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These centers will focus on tracking manufacturing lines and detecting bottlenecks as well as forecasting potential issues in quality and inventory. Novartis hopes this will allow for new, optimized production models, as the company looks to scale up its work in challenging-to-make personalized medicines such as Zolgensma and Kymriah.

Most recently, company opened a new cell and gene therapy manufacturing facility last week in Stein, Switzerland, providing a European base of operations for tailored therapies. Previously, Novartis had to rely on back-and-forth flights across the Atlantic to service patients on the continent, with its sole Kymriah-producing facility being located in New Jersey.

RELATED: Novartis to put AI on every employee's desk through Microsoft partnership

Novartis also plans to use AWS internet of things and computer vision offerings to help improve its manufacturing inspections, by digitally scanning images of sites and tracking individual items to spot for potential risks or delays.

There is a lot we can learn from the AWS team, and while manufacturing is a great starting place, were keen to also explore where else we can apply this technology, Novartis chief digital officer, Bertrand Bodson, said in a statement.

Using data science and digital technologies to reimagine the way we manufacture medicines is not only at the heart of our transformation, but also core to our ambition to bring innovative medicines to patients faster, Bodson added.

RELATED: Novartis' Sandoz goes digital from back office to 'not just apps,' therapeutics

Novartis currently operates more than 60 manufacturing sites worldwide, producing treatments used by nearly 1 billion people. Through its partnership with AWS, the drugmaker hopes to develop standard metrics for site efficiency, deliverable on a single dashboard illustrating global performance.

The company has already been using Amazons computer vision products to double-check that batch manufacturing lines are clear and cleaned after use, and prepared to begin their next scheduled set of tasks. Novartis is also employing AI to extract and analyze data from printed manufacturing documents.

The forthcoming site-based Insight Centers look to make these data available in real time to help avoid unnecessary inventory and machine downtime when producing small-batch and personalized treatments.

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Novartis' digital transformation continues apace with Amazon supply chain tie-up - FierceBiotech

Industrial conglomerate General Electric hosted an investor teach-in in Chicago at a medical conference on Monday. The company reviewed its health-care franchise in a post-biopharma world. GE is selling its biopharma business to Danaher for $21 billion. Now investors have to evaluate the growth and margin potential of what is left.

GE Healthcare is a large global medical device company, said division CFO Monish Patolawala at the event. $17 billion in revenue, midteen margins with strong free cash flow conversion, with good opportunity to continue organic growth and margin expansion while still delivering good free cash flow conversion.

GEs case for its division is health care is a good franchise with solid profitability and decent growth. Bearish analysts dont see it that way.

We come away from the GE Healthcare investor day with no change to our negative view, wrote J.P. Morgan analyst (and known GE bear) Stephen Tusa in a Tuesday research report. While we believe this is an OK asset that has some opportunity to be managed better, we were underwhelmed by [the] presentation.

In particular, Tusa believes low research and development spending is a problem for the division. That theme was picked up by another bearish analyst, Gordon Hasketts John Inch.

Siemens reps at the show expressed pride in the companys outsized R&D budget and new product development, wrote Inch, contrasting GEs R&D spending with its rival Siemens Healthineers (SHL.Germany). For instance, Siemens talked about Dual Source CT scanner which is a technology that Siemens invented years ago but that competitors are just introducing.

GE management pointed out that a larger portion of its health-care business is in servicesfixing the installed based of diagnostic products. That skews the R&D as a percentage of sales comparisons, according to the company.

RBC analyst Deane Dray likes the service business mix. We liked hearing that recurring revenues account for 45% of health cares mix, Dray wrote following the event. And leverage to ongoing trends such as digital [and artificial intelligence] solutions and demand for precision health, which helps tackle waste in the health care industry and improve the accuracy of diagnostics. GE management spent a lot of time laying out how computing power is helping health-care professionals save time and how new technologies create opportunities for personalized medicine.

Tusa and Inch both rate GE shares the equivalent of sell with $5 and $7 price targets, respectively. Dray, on the other hand, rates shares buy and has a $14 price target for the stock.

GEs Healthcare Investor day highlighted the companys diversified global health care portfolio, wrote Citigroup analyst Andrew Kaplowitz. He focused on the outlook for health care in his research report. Despite a lower organic growth [and operating profit] margin profile following the pending sale of BioPharma, [GE Healthcare] could remain well positioned to contribute to growth over time.

The biopharma business has higher margins than the rest of GE Healthcare, which sells large, heavy diagnostic equipment. Kaplowitz is another bull and rates GE shares the equivalent of Buy, with a $14 price target.

Credit Suisse analyst John Walsh sums up the divide between bulls and bears by taking a middle path. We think GE Healthcare management presented a credible growth plan that should be enhanced by margin expansion and greater [free cash flow generation], wrote Walsh, who rates shares Hold. He sees a decent franchise with upside for shareholders if management can improve profitability.

One thing GE management didnt address in Chicago was the potential for a future health-care initial public offering. That was the plan for the division before the biopharma units sale was announced. The $21 billion coming in from that sale eliminated the need to raise money by selling GE Healthcare shares to the public. Now analysts wonder if an IPO is still in the cards.

GE stock dropped Monday and is down again Tuesday, by about 2.7%. Any health-care disappointment or IPO uncertainty, however, isnt the likely culprit. More bad trade news has all industrial stocks lower. On Monday, President Donald Trump threatened tariffs on Brazil, Argentina, and France. Tuesday, he said he might wait until after the election to strike a trade deal with China.

For the year, GE shares are up about 50% year, far better than comparable gains of the S&P 500 index and Dow Jones Industrial Average over the same span.

Write to Al Root at allen.root@dowjones.com

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GE Is Touting Its Health-Care Business, but It Isnt Helping the Stock - Barron's

Getting a blood draw is a standard first step toward almost any medical diagnosis whether your doctor is concerned that you are anemic, have kidney disease or diabetes, or as part of a standard screening during pregnancy. Most of these tests check for a shortage or excess of a particular factor (often a protein) in the blood, which acts as a clue for physicians about a potential health risk.

But what if instead of needing a different blood draw for each suspected health issue, doctors could order up a single blood test that would combine a hundred or more different measures to reveal a holistic portrait of your overall health as well as your risk for a whole host of diseases? Such a test could be administered widely to inform early individualized interventions designed to keep everyone healthy longer.

This is the dream of UC San Francisco physician Peter Ganz, M.D., and colleagues at Colorado-based SomaLogic Inc., who are developing what they call liquid health check technology a single blood test capable of painting a detailed portrait of a persons current health and future disease risks. The technology uses tiny fragments of DNA and RNA called aptamers that are able to identify and measure thousands of different circulating proteins from a small blood sample to reveal information about the health of organs across the body.

In a proof-of-concept study published Dec. 2, 2019, in Nature Medicine, researchers led by Ganz and scientists at SomaLogic and the University of Cambridge, measured the levels of 5,000 different proteins in archived blood plasma samples from nearly 17,000 individuals participating in five different longitudinal health studies. This yielded a total of 85 million protein measurements, making this the largest such study to date, the authors say.

Applying sophisticated machine learning computer algorithms to this massive data set revealed protein expression patterns that correlated with 11 different measures of patients overall health and their risk of developing certain diseases in the years following the initial blood draw. For example, the test could predict how much fat a persons liver contained (associated with liver cirrhosis as well as cardiovascular disease and insulin resistance), their overall level of physical fitness, or whether they later suffered a heart attack or developed diabetes.

We spoke with Ganz who is Maurice Eliaser Distinguished Professor of Medicine at UCSF and director of the Center of Excellence in Vascular Research at Zuckerberg San Francisco General Hospital and Trauma Center about the new study, and about his hopes for liquid health check technology to advance personalized precision medicine. (See the news release by Cambridge University for more details on the study.)

What is a liquid health check and what is your vision for the potential of this technology to improve patients health?

We coined the term liquid health check to refer to information about a persons risks of future diseases, current states of health and modifiable behaviors that can be discerned entirely from different patterns of proteins in blood.

Many people have used blood protein measurements to predict the risk of one disease at a time, but the idea of a liquid health check is to use protein scanning on a large scale to simultaneously predict the risk of numerous diseases and holistically identify an individuals state of health from head to toe.

The results of our studies show that scanning the levels of thousands of blood proteins can simultaneously capture the necessary information to deliver a one-stop test for personalized detection, prevention and treatment of many diseases. This would certainly be much more convenient and likely much less expensive than needing multiple rounds of clinical visits and tests to track down something thats going wrong in your body.

In our newest proof-of-concept study, we were able to predict 11 different kinds of health information about our participants, just by looking at proteins in their blood. Ultimately, our goal is to predict more than 100 diseases or states of health from a single blood sample, which would really be a new paradigm for a blood test.

Which types of health conditions are most amenable to evaluation through a blood test?

From all the studies conducted with blood protein scanning to date, there is evidence that protein patterns can pinpoint propensity for heart disease, diabetes, liver disease, kidney disease, cognitive brain impairment and cancer. We hope that we will ultimately find protein signatures for diseases that afflict most if not all human organs and tissues.

As a cardiologist, how did you get involved in the development of this technology?

I spent most of my career at Brigham and Womens Hospital in Boston as a cardiologist studying human endothelial biology. When I came to UCSF in 2008, I wanted to do something different, but didnt know what it would be. I was introduced to the chief medical officer of SomaLogic quite serendipitously, but I came out of that meeting with my eyes opened about the potential of the technology they were developing.

I have been on their Medical Advisory Board ever since I dont take any money from them or any other company and have basically helped to guide the development of clinical applications of their technology.

The ability to analyze blood proteins and link them to human disease is going to be a critical tool of the precision medicine revolution.Peter Ganz, M.D.

Initially we focused on cardiovascular applications, in part because of my background, and in 2016 we published a study in JAMA where we used the technology to predict the future risk of heart attacks, strokes, heart failure and death based on nine different blood proteins.

After that paper, we decided that with a technology that can measure 5,000 proteins simultaneously in a sample of blood, why underutilize this platform, measuring just nine proteins to inform cardiovascular outcomes? We talked about how we could take advantage of a platform that could measure so many different proteins, and thats how we arrived at the idea of developing liquid health checks a holistic approach to disease prevention and management that is not constrained by any one specialty.

How are you collaborating with SomaLogic to develop liquid health check technology? How have new technologies made this vision possible?

This project represents an exemplary collaboration between academic institutions and an industry partner. SomaLogic has developed a unique technology to quantify thousands of blood plasma proteins at once, while my academic colleagues and I have played a key role in linking blood protein patterns to propensity for developing illnesses or for maintaining good health in studies that have required participation of many thousands of patients worldwide.

The ability to analyze blood proteins and link them to human disease is going to be a critical tool of the precision medicine revolution. In fact, these protein scans are not just a fantasy in the distant future. A limited initial release version of the protein test is now available for clinical use.

One thing I think is very important for establishing confidence in this technology is that we are all dedicated to openness and transparency. From the get-go we agreed that everything thats learned will be published, and weve even pushed journals to publish hundreds of pages of supplementary materials to ensure that anyone who wants to can replicate our results.

Disclosures: Dr Ganzs proteomic research is supported by National Institutes of Health grants 1RO1HL129856, 1UO1DK108809, and 1R01AG052964. Dr. Ganz serves on the medical advisory board to SomaLogic Inc., for which he accepts no salary, honoraria, or any other financial incentives.

Read more here:
Toward a head-to-toe health check from a single blood test - University of California

According to the latest study conducted byMarket Growth Analysisthe global market for precision medicine is anticipate grow manifold, reflecting a robust CAGR of over XX% during 2018 to 2025.

Rapid augmentation of the medicine industry across the globe will certainly benefit the global market for precision medicine. In addition, factors such as growing infrastructural development, higher investments, streamlined drug approval systems along with companion diagnostics are expected to favor the overall market growth during the assessment period. Cost-effective DNA profiling and increasing prevalence of carcinogenic diseases worldwide are additional factors that are projected to propel the market growth. Moreover, apt storage of genome data is of great significance to the global market for precision medicine as demand for data medicare is on the rise. However, acute data storage capacity, data privacy breach and discrepancies in funding systems and hefty price tag of personalized drugs may deter the market growth in the near future.

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The global market for precision medicine has been categorized into various parent segments that are further segmented into smaller sub-divisions.

On the basis of technology, next-gen sequencing, bioinformatics and drug discovery technology are expected to be the technologies highlighting the expanding the market width in forthcoming years. Based on applications, the oncology segment is expected to witness an overwhelming growth and is estimated to reach US$ XX Billion over 2025, reflecting a staggering XX% CAGR. This is primarily owing to increasing prevalence of tumor-related disease amongst the global geriatric population. On the other hand, increasing cases of arthritis will favor the growth of immunology segment, which is expected to surpass US$ XX Million in revenues by 2025 end.

Vendor News

Key players operating in the global market for precision medicine include Eli Lilly And Company, Novartis AG, AstraZeneca and Laboratory Corporation of America Holdings. Most of the companies are implementing market strategies involving mergers, tie-ups and acquisitions. Increasing collaboration between healthcare and IT is expected to deliver fruitful gains to the market, expanding the overall business canvas for the stakeholders in the upcoming years.

Request for enquiry on This Report at: http://marketgrowthanalysis.com/reports/enquiry/436

The popularity of precision medicine has grown significantly across various parts of the world, hence on the basis of region, the markets for precision medicine in Asia Pacific, North America, Europe, Latin America, and the Middle East and Africa (MEA) is set to achieve new figures of growth over the next eight years. Precisely, the market in North America is expected to present new lucrative opportunities, occupying over XX% share of the market during the forecast period. In addition, the region is estimated to surpass a market valuation of over US$ XX Million by the end of 2025.

The US and Canada will be the heavyweights of the global market owing to the existence of well-established medical industries in both the countries. In Europe, the market is expected to witness a steady growth and will increase its revenues charts close to US$ XX Million, riding on a healthy CAGR of over XX% during the assessment period. This is largely due to the increasing demand for precision medicines in countries such as France, UK, Italy and Germany. The Asia Pacific region is another region which is considered to be full of business potentials. The region is projected to increase at over XX% CAGR to reach approximately US$ XX Million by 2025 end. The market in APAC will be heavily dominated by Japan, while, India and China will compete for the second spot. Likewise, the in Latin America the market is expected to surge at a pace in terms of revenue over 2025. However, MEA will witness a sluggish growth of the market which is attributed to the lack of initiatives for conductive extensive research and development activities.

Browse more detail information about this report visit at: http://marketgrowthanalysis.com/precision-medicine-market

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Precision Medicine Market Detailed Analysis of Current Industry Figures with Forecasts Growth By 2025 - Crypto News Byte

Further Strengthens Business Development Team with Key Hire

PARSIPPANY, N.J., Dec. 05, 2019 (GLOBE NEWSWIRE) -- Interpace Biosciences subsidiary, Interpace Pharma Solutions today announced that it is continuing to expand a previously announced partnership agreement to jointly develop, promote and offer translational studies and clinical trial solutions to biotech and pharmaceutical companies with Genecast (Beijing) Biotechnology Co. Ltd (Genecast) of the Peoples Republic of China (PRC). Genecast is a leader in offering diagnostic products and services in the field of oncology and providing a wide range of diagnostic services to pharmaceutical and biotech companies in the PRC. Interpace is sending members of its technical/scientific and business development teams to China this week to begin the tech transfer requirements to support over $3 million of recently secured new business with global pharmaceutical companies.

Michael McCartney, Chief Commercial Officer of Interpace Pharma Solutions commented, We will be joining the Genecast business development team in China to jointly promote our capabilities of tumor profiling testing and clinical testing services in China and will be traveling to Beijing, Suzhou and Shanghai to meet with Genecast pharma customers who are in need of Interpace Pharma Solutions services Mr. McCartney also added We are thrilled to announce the addition of Gordon Vansant, Ph.D. a highly regarded industry expert to our BD team. Dr. Vansant has deep relationships and contacts in China to further strengthen and expand our penetration in China and Asia and will lead our BD efforts in the Southwest US, headquartered out of San Diego.

Du Bo, Co-Founder and CEO of Genecast, said, We are excited that the partnership with Interpace Pharma Solutions is already working and we believe will strengthen our capabilities to provide our customers with high-quality, streamlined one-stop testing services globally. Interpace Pharma Solutions development is in line with our strategy of helping pharmaceutical and biotech companies on a global basis accelerate their biomarker-driven drug development and drive precision medicine forward.

Jack Stover, President & CEO of Interpace Biosciences commented, We are pleased with the new business already being booked as a result of our relationship with such a high-quality partner as Genecast and we are pleased to have such an experienced and successful executive as Dr. Vansant join our Pharma Solutions BD team. We look forward to expanding our partnership with Genecast as well as expanding our international capabilities in Europe, Asia and elsewhere in the near future, concluded Stover.

About Interpace Biosciences

Interpace Biosciences is a leader in enabling personalized medicine, offering specialized services along the therapeutic value chain from early diagnosis and prognostic planning to targeted therapeutic applications.

Interpace Pharma Solutions is a market leader in providing pharmacogenomics testing, genotyping, and biorepository services to the pharmaceutical and biotech industries. The Biopharma Business also advances personalized medicine by partnering with pharmaceutical, academic, and technology leaders to effectively integrate pharmacogenomics into their drug development and clinical trial programs with the goals of delivering safer, more effective drugs to market more quickly, and improving patient care.

Interpace Diagnostics is a fully integrated commercial and bioinformatics business unit that provides clinically useful molecular diagnostic tests, bioinformatics and pathology services for evaluating risk of cancer by leveraging the latest technology in personalized medicine for improved patient diagnosis and management. Interpace has four commercialized molecular tests and one test in a clinical evaluation process (CEP).

For more information, please visit Interpace Biosciences website atwww.interpace.com.

Genecast (Beijing) Biotechnology Co. Ltd.

Genecast is a leader in offering diagnostic products & services in the field of oncology and providing a wide range of diagnostic services to pharmaceutical and biotech companies in the Peoples Republic of China (PRC). Genecasts laboratories have met all applicable standards for accreditation including accreditation from the CAP and earned top marks in a number of external quality assessments carried out by CAP, EMQN, the Clinical Test Center of the National Health Commission of China and Center of Clinical Laboratories of Shanghai.

Genecast has formed collaborations with more than 20 pharmaceutical and biotech companies in providing comprehensive pre-clinical and clinical testing services.

For more information, please visit Genecasts website at http://english.genecast.com.cn.

Media Contact:Dan ChenGenecast (Beijing) Biotechnologychen.dan@genecast.com.cn

Forward Looking Statements on Behalf of Interpace Biosciences

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995, relating to the Companys future financial and operating performance. The Company has attempted to identify forward looking statements by terminology including believes, estimates, anticipates, expects, plans, projects, intends, potential, may, could, might, will, should, approximately or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. These statements are based on current expectations, assumptions and uncertainties involving judgments about, among other things, future economic, competitive and market conditions and future business decisions, all of which are difficult or impossible to predict accurately and many of which are beyond the Companys control. These statements also involve known and unknown risks, uncertainties and other factors that may cause the Companys actual results to be materially different from those expressed or implied by any forward-looking statement. Additionally, all forward-looking statements are subject to the Risk Factors detailed from time to time in the Companys most recent Annual Report on Form 10-K, Quarterly Reports on Form 10-Q and other SEC filings. Because of these and other risks, uncertainties and assumptions, undue reliance should not be placed on these forward-looking statements. In addition, these statements speak only as of the date of this press release and, except as may be required by law, the Company undertakes no obligation to revise or update publicly any forward-looking statements for any reason.

INTERPACE CONTACTS:Investor RelationsJoseph Green, Edison Groupjgreen@edisongroup.com

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Interpace Biosciences Expands Strategic Partnership Activities with Genecast Biotechnology in China - GlobeNewswire

The Ibex Second Read System for breast is now deployed at Maccabi's pathology institute, making it the first lab in the world to implement AI-powered cancer diagnostics for breast biopsies in its routine clinical practice

Tel Aviv, Israel /PRNewswire/ - Ibex Medical Analytics, the pioneer in artificial intelligence (AI)-powered cancer diagnostics, and the KSM Research and Innovation Institute at Maccabi Healthcare Services, announce the deployment of the Ibex Second Read System for breast at Maccabi's pathology institute, the largest pathology lab in Israel.

Ibex Second Read is the first-ever system that detects and grades cancer in breast biopsies. The system uses an artificial intelligence (AI) powered algorithm to analyze cases in parallel to pathologists and compares between the pathologists' diagnoses and the algorithm's findings, subsequently alerting in case of discrepancies with high clinical importance (e.g. a missed cancer). Now used in routine clinical practice, this clinical-grade product enhances the quality control process in the lab and provides a safety net, resulting in decreased diagnostic error rates and a more efficient workflow.

The algorithm used by the Second Read system was developed by Ibex using advanced machine learning techniques and trained on data sets from Maccabi's pathology institute. The institute was the first pathology lab in the world to implement an AI powered cancer diagnostic system in its routine practice - the Ibex Second Read system for prostate which is now deployed in pathology labs worldwide with demonstrated success in detecting missed cancer cases.

"We are proud to roll out a first of a kind product that improves the diagnosis of breast cancer - the most common cancer in women with over 2 million new cases globally each year. The Second Read for breast is a landmark achievement for our team of pathologists, computer scientists and AI specialists and for our partnership with Maccabi Healthcare Services, enabling us to extend the reach of our product suite. The future looks brighter than ever for Ibex, with a growing interest from pathology labs in our products and new tissue types we expect to introduce during 2020" said Joseph Mossel, Ibex Medical Analytics' Co-Founder and CEO.

"We are excited to use the Second Read system for breast cancer detection in our routine practice following a successful research and partnership with Ibex, led by the KSM Research and Innovation Institute. At Maccabi Healthcare Services we are constantly looking for new technologies that can make a real impact on patient care. We believe that adding a security layer to our pathology reporting will improve accuracy levels of our cancer diagnosis, as already proven by the Second Read's prostate module that we have been using in the past 18 months," said Prof. Varda Shalev, Managing Director of the Kahn-Sagol-Maccabi Research and Innovation Institute at Maccabi Healthcare Services.

About Ibex Medical AnalyticsIbex provides the first-ever AI-powered cancer diagnostics solution in routine clinical use in pathology labs, supporting pathologists in delivering accurate, rapid and objective diagnosis of prostate and breast biopsies. Ibex' product is deployed across the laboratory's workflow and builds on deep learning algorithms developed by a team of pathologists, data scientists and software engineers. The company has raised $14 million from prominent VC funds and corporate investors. For more information visit us at http://www.ibex-ai.com.

About Maccabi Healthcare ServicesMaccabi Healthcare Services is one of the world's largest healthcare providers with 2.5 million members. Maccabi has long been recognized, both in Israel and abroad, as a unique and innovative health care system which leads the way in cutting edge medical technology, comprehensive and integrated computerized information systems, costeffective management and sophisticated monitoring and evaluation tools.

The Kahn-Sagol-Maccabi Research and Innovation Institute's vision is to accelerate precision medicine and lead in big data analytics. We aim to increase the amount and quality of medical research being performed at any given moment in Israel and worldwide and partner with the most advanced AI companies to develop innovative, predictive and personalized tools in service of the new era of medicine.

Continued here:
Ibex Medical Analytics And The Kahn-Sagol-Maccabi (KSM) Research And Innovation Institute At Maccabi Healthcare Services Roll Out The First-Ever...

December has always been a time for reflection and anticipation for whats to come the following year. Considering that 2020 marks the beginning of a brand new decade, theres extra excitement for what the year will bring and what tone it will set for the entire decade. It seems that every year is an exciting year for the pharma industry and 2020 stays on course. Pharma professionals have many exciting trends to monitor for the year ahead.

Perhaps the most noteworthy trend of them all is the prevalence of China on the pharma market in the first place. For decades, China has not been a major player certainly no source for meaningful innovation or trendsetting power. This, however, has changed dramatically in the last decade as the government heavily invested in the biopharma industry, which has seen the Chinese market grow by an estimate 25% annually over the course of five years between 2012 and 2016. Current estimations place the value of the market to hit USD $48.8 billion by 2021.

These numbers alone should alert the international community at large to pay attention, especially when it seems that Chinas main priority is the developments in bio-processing with the export of biologics identified as a chief objective.

Preventive healthcare and personalized medicine are also picking up steam. Not every disease can be cured, which is where pharmaceutical innovations strive to prevent its contraction. Perhaps the most significant success that preventive medicine has observes is with HIV. Products like Truvada have made all the difference in slowing down the spread of the virus. This approach is only going to come to the forefront in coming years. In the same breath, the pharmaceutical industry has set its sights on improving health care through personalized medicine, which breaks away from the average and investigates deeper the unique biodome of the patient. The technology relied on full patient data and customized medicines to create a custom-tailored treatment.

Were not in the 21st century, if we dont speak about AI and digitalisation as part of Industry 4.0 in relation to pharmaceuticals. Artificial Intelligence is already poised to become the tool that will win margins and improve budget spending. Its no secret that the pharmaceutical industry is in dire need of improving efficiency in order to reduce its wastefulness and AI is being developed to then handle these processes.

Digital solutions are set to help with breakthroughs in the Value Added Medicines (VAM) sector through an improvement in patient reports. Given the rise of medical wearable technology, it will be easier to collect real patient usage metrics to support VAM players in the long run.

The safest way to gain a deep insight into pharma trends is to attend the trade shows known for a higher commitment to informing its audience about how their professional landscape is changing.

CPhI Worldwide:

Perhaps the first event anyone involved in pharmaceuticals thinks about. The unique feature here is the distinct separation of CPhI Worldwide into six areas that in turn embody each of the pharmaceutical supply chain stages. This allows for more in-depth digging and research into highly specialized trends.

Expopharm: As a leading meeting point for the actors on the global pharmaceutical market, Expopharm presents a full picture of the dynamic market trends and is also a platform for exhibitors to make announcements regarding their personal technological innovations.

MEDICA: Held alongside COMPAMED, MEDICA is the umbrella trade show where the whole of medicine is represented and in that sense youll experience pharmaceutical news and trends in relation to the broader medical and technological fields.

IDS: IDS enjoys a reputation of the most important dentistry trade show in the world, so if youre specialized in dentistry pharmaceuticals IDS is where you need to come to receive highly targeted news, product launches and announcements.

Arab Health: The MENA region has been known for its high-paced rates of innovation and Arab Health is an entry point into a highly competitive market that has its own, entirely different feel. Some trends and innovations are first talked about during this show.

But what about vitamins and supplements?

Adjacent to pharmaceuticals, but not as heavily regulated are the markets for essential supplements and vitamins, which are also in the great throes of transformation for the upcoming year. Were in for the year of watermelon seeds, which have emerged as the surprise super food recently, and a fervent love of all things moringa. The markets that are shaping up to be big earners are the sleep supplements and pet supplements. Whatever you decide to put into your body should be the very best and in that sense its good to have a list of supplement brands that have been recognized for their high quality.

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It's Going to Be a Big Year for Pharma Trends in 2020 Here's What to Watch out For - - VENTS Magazine

Company also announces CRISPR Therapeutics CEO Samarth Kulkarni, Ph.D., Joins its Board of Directors

CAMBRIDGE, Mass. and NEW YORK, Dec. 5, 2019 /PRNewswire/ --Black Diamond Therapeutics, Inc., a precision oncology medicine company pioneering the discovery and development of small molecule, tumor-agnostic therapies, today announced the completion of an oversubscribed Series C financing of $85 million led by Boxer Capital of the Tavistock Group. Additional new investors Wellington Management Company, BVF Partners L.P., Deerfield Management, funds managed by Janus Henderson Investors, Casdin Capital, and Logos Capital joined current investors Versant Ventures, New Enterprise Associates, RA Capital Management, Nextech Invest, Invus, Perceptive Advisors, City Hill Ventures, and Roche Venture Fund in the round.

Black Diamond Therapeutics Logo (PRNewsfoto/Black Diamond Therapeutics, Inc.)

Proceeds from the Series C financing will be used to support the Company's growth and advance the development of Black Diamond's lead product candidates targeting oncogenic driver mutations of the ErbB kinases in epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2). The Company plans to start a combined Phase 1/2 clinical trial of its most advanced product candidate, BDTX-189, in the first half of 2020. The funding will also support the continued expansion of the Company's earlier stage research programs and proprietary Mutation-Allostery-Pharmacology (MAP) platform to identify and target oncogenic mutations. The Company initially operated in stealth mode from New York and from Versant's Basel-based Ridgeline Discovery Engine and has raised $194 million since its founding.

David M. Epstein, President and CEO of Black Diamond commented, "We are privileged to have this impressive syndicate of thought-leading investors share our commitment to patients and support our vision to discover and develop therapies that will potentially transform how cancer is treated. There arecurrently no drugs approved by the FDA to target certain allosteric and other EGFR and HER2 mutations that are prevalent in a variety of cancers with a single therapy, including in patients with deadly cancers like lung cancer or glioblastoma that express these mutations. This funding will help accelerate development of our lead product candidates targeting undrugged oncogenic driver mutations of EGFR and HER2 so that we can get potential new treatments to patients as quickly as possible."

Commenting on the investment, Aaron Davis, CEO of Boxer Capital said, "Black Diamond's ground-breaking MAP platform could revolutionize how we discover and develop new oncology treatments, particularly for some of the most difficult-to-treat cancers. We are delighted to partner with this group of leading investors and experienced management team in this endeavor."

In addition, Black Diamond announced the appointment of Samarth (Sam) Kulkarni, Ph.D., to its Board of Directors. An industry leader with expertise in strategy and operations in biotech and a wide range of pioneering therapeutic technologies, Sam currently serves as CEO of CRISPR Therapeutics AG. Hejoined CRISPR in 2015 in the early stages of the company as Chief Business Officer (CBO), and then served as President and CBO before being named its CEO in 2017.

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"We are thrilled to have Sam join Black Diamond's Board of Directors. His wealth of experience and proven track record of strategic business accomplishments and advancing innovative therapeutic technologies will be invaluable as we continue to progress our portfolio and design our programs for clinical success," added Dr. Epstein.

Prior to CRISPR, Sam was a partner at McKinsey & Company, where he had a leading role in the Pharmaceutical and Medical products practice. While at McKinsey, he co-led the biotechnology practice and focused on topics ranging from strategy to operations and led initiatives in areas such as personalized medicine and immunotherapy. Sam also serves as the Chairman of the Board of Directors of Casebia Therapeutics, a joint subsidiary formed by CRISPR and Bayer. He received a Ph.D. in bioengineering and nanotechnology from the University of Washington and a B. Tech. from the Indian Institute of Technology. While at the University of Washington, Sam conducted research on the delivery of biological drugs and in the field of molecular diagnostics. He has authored several publications in leading scientific and business journals.

"It is an exciting time to be joining Black Diamond'sBoard of Directors. The Company has tremendous momentum and I believe has significant potential to change how we treat cancer through its MAP platform and discovery engine," said Dr. Kulkarni.

Black Diamond's MAP platformBlack Diamond's Mutation-Allostery-Pharmacology (MAP) platform is built on three central pillars discover, reveal, and target. The Company uses population-level cancer genetic data obtained from all tumor types to identify potential families of mutations that occur within individual oncogenes and rank the mutations for potential oncogenicity. Black Diamond then uses its MAP platform to understand the mechanism for oncogenic activation and its team of experienced medicinal chemists then develops mutation spectrum-selective drugs for the identified targets.

Black Diamond's MAP platform has generated a pipeline of orally available, potent, and selective small molecule kinase inhibitors that target a range of driver mutations in cancer. The Company'sfirst two disclosed programs are targeting groups of EGFR and HER2 allosteric mutants.

About Black DiamondBlack Diamond Therapeutics is a precision oncology medicine company pioneering the discovery of small molecule, tumor-agnostic therapies. Black Diamond targets undrugged mutations in patients with genetically defined cancers. Black Diamond is built upon a deep understanding of cancer genetics, protein structure and function, and medicinal chemistry. The Company's proprietary technology platform, Mutation-Allostery-Pharmacology, or MAP, platform, is designed to allow Black Diamond to analyze population-level genetic sequencing data to identify oncogenic mutations that promote cancer across tumor types, group these mutations into families, and develop a single small molecule therapy in a tumor-agnostic manner that targets a specific family of mutations. Black Diamond was founded by David M. Epstein, Ph.D. and Elizabeth Buck, Ph.D., and, beginning in 2017, together with Versant Ventures, began building the MAP platform and chemistry discovery engine. For more information please visit http://www.bdtherapeutics.com.

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SOURCE Black Diamond Therapeutics, Inc.

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Black Diamond Therapeutics Closes $85 Million Series C Financing - Yahoo Finance

The report on the Personalized Medicine Market published by Future Market Insights (FMI) provides a clear understanding of the flight of the Personalized Medicine Market over the forecast period 2016 2026. The study introspects the various factors that are tipped to influence the growth of the Personalized Medicine market in the upcoming years. The current trends, growth opportunities, restraints, and major challenges faced by market players in the Personalized Medicine Market are analyzed in the report.

The study reveals that the global Personalized Medicine Market is projected to reach a market value of ~US$XX and grow at a CAGR of ~XX% during the assessment period. Further, a qualitative and quantitative analysis of the Personalized Medicine Market based on data collected from various credible sources in the market value chain is included in the report along with relevant tables, graphs, and figures.

ThisPress Release will help you to understand the Volume, growth with Impacting Trends. Click HERE To get SAMPLE PDF (Including Full TOC, Table & Figures) at https://www.futuremarketinsights.co/reports/sample/REP-GB-1511

Key Takeaways of the Report:

The report addresses the following doubts related to the Personalized Medicine Market:

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Key Players

Some key players in this market are Roche Holding AG, Astra Zeneca PLC, Vertex Pharmaceuticals Inc., Qiagen Inc., BD (Becton Dickinson & Co., Merck & Co. Inc., Pfizer Inc., American Association for Cancer Research, Siemens Healthcare Diagnostics, Inc. among others.

The research report presents a comprehensive assessment of the market and contains thoughtful insights, facts, historical data, and statistically supported and industry-validated market data. It also contains projections using a suitable set of assumptions and methodologies. The research report provides analysis and information according to categories such as market segments, geographies, types, technology and applications.

The report covers exhaustive analysis on:

Regional analysis includes

North America (U.S., Canada)

Latin America (Mexico. Brazil)

Western Europe (Germany, Italy, France, U.K, Spain, Nordic countries, Belgium, Netherlands, Luxembourg)

Eastern Europe (Poland, Russia)

APEJ (China, India, ASEAN, Australia & New Zealand)

Japan

Middle East and Africa (GCC, S. Africa, N. Africa)

The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.

Report Highlights:

Detailed overview of parent market

Changing market dynamics in the industry

In-depth market segmentation

Historical, current and projected market size in terms of volume and value

Recent industry trends and developments

Competitive landscape

Strategies of key players and products offered

Potential and niche segments, geographical regions exhibiting promising growth

A neutral perspective on market performance

Must-have information for market players to sustain and enhance their market footprint.

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Personalized Medicine Market expected to be valued at ~US$ XX Mn/Bn during the forecast period 2016 2026 - Weekly News Times

While resistance can often make it a challenge to treat mantle cell lymphoma, therapies have come a long way in recent years thanks to the emergence of personalized treatment and the use of BTK inhibitors, according to one expert.

Ruan, a hematologist and oncologist from Weil Cornell Medicine in New York City, recently sat down with OncLive, CUREs sister publication, to discuss the treatment trends in this disease space.

We're moving toward precision medicine and personalized treatment (in MCL), said Ruan. The objective is to overcome resistance and come up with treatment plans that address the underlying disease biology and take personal factors about the patients into consideration.

When asked about the novel agents that are currently showing promise in MCL, Ruan explained that BTK inhibitors have resulted in highoverall response rates (ORRs), more complete remissions (CRs) and a lower number of side effects in this patient population.

Since the approval of Revlimid (lenalidomide) in 2013, a number of newer BTK inhibitors have been approved, with first-generation Imbruvica (ibrutinib) standing out as the top choice for many. So far, this class of agents has the best single-agent activity in MCL to date, explained Ruan. For example, ibrutinib would give about a 65% to 67% ORR, and about 20% of that would be CRs. In contrast, lenalidomide would give you about a 30% ORR and up to about 8% CR.

A newer BTK inhibitor, Calquence (acalabrutinib), is considered just as effective as Imbruvica with an overall response rate of 81% and complete response in 40% of patients who took it during the phase 2 study that led to its approval. That's quite remarkable for a single agent for patients who have relapsed/refractory MCL, Ruan said.

The field continues to grow with the testing of new agents, including BCL-2 inhibitor, Venclexta (venetoclax), which is currently approved in chronic lymphocytic leukemia and other indolent B-cell non-Hodgkin lymphomas. In MCL, we have data to suggest that it has promising activity as a single agent, she said. Currently, it's being studied in combination with a variety of other agents, including BTK inhibitors. They seem to work very well and are helping to move treatment away from chemotherapy.

However, treating MCL can be challenging because of treatment resistance, explained Ruan. All of the agents are being introduced, tested, and approved in the setting of relapsed disease, said Ruan. That is a big challenge for a sizable portion of patients who do not respond maybe they have a genetic mutation that is not responsive to targeted therapy or they develop a secondary mutation in the process of being treated and then they become resistant.

The issue of resistance is important to consider when treating MCL, according to Ruan. We have to provide novel agents that are sensitive to the disease at every stage of the evolution and come up with additional therapies that can overcome the resistance, she said.

In the future, Ruan predicts the shift toward precision medicine and personalized treatment will continue. The objective is to overcome resistance and come up with treatment plans that address the underlying disease biology and take personal factors about the patients into consideration, she said. This is important for us to understand MCL individually.

This precise approach would mean doing more genetic analysis to determine what type of disease is being treated in order to create a treatment plan that would provide the most benefit for the patient.

If we could know (about mutations) ahead of time, we could have the treatment designed and tailored to maximize treatment effectiveness and minimize adverse events, said Ruan.

It doesn't make sense to subject patients to all of the cytotoxicity associated with conventional intensive chemotherapy while other options, such as participation in clinical trials with novel agents, could be very effective.

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Precision Medicine and Personalized Treatments Shifting the Tide in Mantle Cell Lymphoma - Curetoday.com

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Relevant clinical advances that improve outcomes for patients with glioblastoma have been few and far between over the last two decades, said Frederic Sottilini, CEO of CarThera. Despite multimodal therapy, median survival remains around 15 months for these patients, virtually all of whom recur. Our goal is to optimize the selection and delivery of drug therapies to extend the lives of patients with glioblastoma.

The two companies were brought together by one of the worlds leading neuro-oncology and glioblastoma experts, John de Groot, M.D., professor and chairman ad interim, The University of Texas MD Anderson Cancer Center, who recognized the synergistic nature of their respective clinical initiatives. CarThera is currently conducting a multi-center clinical study of its novel ultrasound technology, SonoCloud-9, designed to increase the permeability of the blood brain barrier to improve the delivery of chemotherapeutic agents to the brains of patients with recurrent glioblastoma. KIYATEC is conducting a multi-center clinical study of its ex vivo 3D cell culture technology to accurately predict pre-treatment, patient-specific response to recommended standard of care cancer drugs for newly diagnosed and recurrent glioblastoma.

As someone who cares for patients with glioblastoma, I applaud the efforts of CarThera and KIYATEC to bring evidence-based advances to the clinic for the purpose of improving outcomes for patients with glioblastoma, said Dr. de Groot. I envision these two technologies as being complementary with the potential to transform the way in which neuro-oncologists manage glioblastoma patients.

Under the terms of the clinical collaboration, KIYATEC will conduct ex vivo drug response profiling on glioblastoma tissue samples from patients enrolled in CarTheras clinical study. CarThera will benefit from having ex vivo drug response profiling for patients enrolled in its study, while KIYATEC will correlate its patient-specific, pre-treatment drug response predictions with actual clinical outcomes of patients in CarTheras study. For both companies, this collaboration represents an opportunity to enrich their portfolios of clinical evidence with the goal of helping clinicians improve outcomes for their patients with glioblastoma.

Both of our companies are dedicated to ensuring that glioblastoma patients receive the most appropriate drug therapy at the right time, and that the efficacy of that therapy is maximized to its fullest therapeutic potential, said Matthew Gevaert, CEO and co-founder of KIYATEC. We believe that this clinical collaboration has the potential to help us accelerate and deliver on the long-awaited promise of personalized medicine for these deserving patients.

Both companies will be sending delegates to the 24th Annual Meeting of the Society for Neuro-Oncology, November 20-24 in Phoenix, Arizona.

About KIYATEC, Inc. KIYATEC leverages its proprietary ex vivo 3D cell culture technology platforms to accurately model and predict response to approved and investigational cancer drugs targeting a spectrum of solid tumors. The companys Drug Development Services business works in partnership with leading biopharmaceutical companies to unlock response dynamics for its investigational drug candidates across the majority of solid tumor types. The companys Clinical Services business is currently engaged in the validation of clinical assays as well as investigator-initiated studies in ovarian cancer, breast cancer, glioblastoma and rare tumors, in its CLIA-certified laboratory. To learn more about KIYATEC, visit http://www.kiyatec.com.

About CarThera CarThera designs and develops innovative therapeutic ultrasound-based medical devices for treating brain disorders. The company is a spin-off from AP-HP, Greater Paris University Hospitals, the largest hospital group in Europe, and Sorbonne University. Since 2010, CarThera has been leveraging the inventions of Professor Alexandre Carpentier, a neurosurgeon at AP-HP who has achieved worldwide recognition for his innovative developments in treating brain disorders. CarThera developed SonoCloud, an intracranial ultrasound implant that temporarily opens the blood-brain barrier (BBB). CarThera is based at the Brain and Spine Institute (Institut du Cerveau et de la Moelle pinire, ICM) in Paris, France, and has laboratories at the Bioparc Lannec business incubator in Lyon, France. The company, led by Frederic Sottilini (CEO), works closely with the Laboratory of Therapeutic Applications of Ultrasound (Laboratoire Thrapie et Applications Ultrasonores, LabTAU, INSERM) in Lyon.www.carthera.eu

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CarThera and KIYATEC Collaborate in Effort to Bring Personalized Medicine to Patients Stricken by Brain Cancer - BioSpace

This report provides data on patterns, improvements, target business sectors, materials, limits, and advancements. By thinking from the customers perspective, a team of researchers, forecasters, analysts, and industry experts work carefully to formulate this Global Precision Medicine Market report. Furthermore, it works to determine the impact of buyers, substitutes, new entrants, competitors, and suppliers on the market. This gives more accurate understanding of the market landscape, issues that may affect the industry in the future, and how to best position specific brands. The Global Precision Medicine Market report helps to develop a successful marketing strategy for your business and acts as a backbone to the business.

Global Precision Medicine Marketto grow with a substantial CAGR in the forecast period of 2019-2026. Growing prevalence of cancer worldwide and accelerating demand of novel therapies to prevent of cancer related disorders are the key factors for lucrative growth of market

Key Market Players:

Few of the major competitors currently working in the global precision medicine market areNeon Therapeutics, Moderna, Inc, Merck & Co., Inc, Bayer AG, PERSONALIS INC, GENOCEA BIOSCIENCES, INC., F. Hoffmann-La Roche Ltd, CureVac AG, CELLDEX THERAPEUTICS, BIONTECH SE, Advaxis, Inc, GlaxoSmithKline plc, Bioven International Sdn Bhd, Agenus Inc., Immatics Biotechnologies GmbH, Immunovative Therapies, Bristol-Myers Squibb Company, Gritstone Oncology, NantKwest, Inc among others.

Global Precision Medicine Market By Application (Diagnostics, Therapeutics and Others), Technologies (Pharmacogenomics, Point-of-Care Testing, Stem Cell Therapy, Pharmacoproteomics and Others), Indication (Oncology, Central Nervous System (CNS) Disorders, Immunology Disorders, Respiratory Disorders, Others), Drugs (Alectinib, Osimertinib, Mepolizumab,Aripiprazole lauroxil and Others), Route of Administration (Oral,Injectable), End- Users (Hospitals, Homecare, Specialty Clinics, Others), Geography (North America, South America, Europe, Asia-Pacific, Middle East and Africa) Industry Trends and Forecast to 2026

Competitive Analysis:

The precision medicine market is highly fragmented and is based on new product launches and clinical results of products. Hence the major players have used various strategies such as new product launches, clinical trials, market initiatives, high expense on research and development, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of mass spectrometry market for global, Europe, North America, Asia Pacific and South America.

Market Definition:

Precision medicines is also known as personalized medicines is an innovative approach to the patient care for disease treatment, diagnosis and prevention base on the persons individual genes. It allows doctors or physicians to select treatment option based on the patients genetic understanding of their disease.

According to the data published in PerMedCoalition, it was estimated that the USFDA has approved 25 novels personalized medicines in the year of 2018. These growing approvals annually by the regulatory authorities and rise in oncology and CNS disorders worldwide are the key factors for market growth.

Market Drivers

Market Restraints

Key Developments in the Market:

Competitive Analysis:

Global precision medicine market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of global precision medicine market for Global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.

Market Segmentation:

By technology:-big data analytics, bioinformatics, gene sequencing, drug discovery, companion diagnostics, and others.

By application:- oncology, hematology, infectious diseases, cardiology, neurology, endocrinology, pulmonary diseases, ophthalmology, metabolic diseases, pharmagenomics, and others.

On the basis of end-users:- pharmaceuticals, biotechnology, diagnostic companies, laboratories, and healthcare it specialist.

On the basis of geography:- North America & South America, Europe, Asia-Pacific, and Middle East & Africa. U.S., Canada, Germany, France, U.K., Netherlands, Switzerland, Turkey, Russia, China, India, South Korea, Japan, Australia, Singapore, Saudi Arabia, South Africa, and Brazil among others.

In 2017, North America is expected to dominate the market.

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Global Precision Medicine Market Share 2019 Analysis With Observational Studies of Neon Therapeutics, Moderna, Inc, Merck & Co., Inc, Bayer AG,...

For centuries, medicine has largely relied on a single primary source of information for the diagnosis and treatment of disease: individual patients. This data stream has become increasingly complex over time due to advances in imaging, biochemistry and genetics, but it is still patient-based.

Now, a second stream is emerging that I believe is likely to impact the entire healthcare delivery system, both in terms of outcomes and economics: population-based data. The sources of this data could include census records, various government agencies and community health records. The information it provides could span neighborhood and housing conditions, economic stability, education levels, social and community conditions and the availability of healthcare. All of these could contribute to a three-dimensional view of the patient and provide insights into treatment options and the management of chronic conditions. In fact, research (via the National Academy of Medicine) suggests that social determinants account for 80% to 90% of "modifiable contributors to healthy outcomes."

This figure is more than an interesting statistic. It has demonstrable real-world consequences. For example, a Maricopa County, Arizona, program that incorporates social determinants played a significant role in a 67% decrease in suicides in its first three months. The data collected related to poverty, food and housing insecurity, and environmental exposures such as homes with lead paint. Efforts to reduce some of the problems that were discovered, such as delivering meals or installing air conditioners, were likely central to the programs success.

The amount of healthcare data is huge and growing. According to Research and Markets, it more than quadrupled to 700 exabytes from 2013 to 2017 and is projected to triple again to 2,314 exabytes by 2020. Its potential value to businesses is even more impressive. For example, EY estimates that the value of the U.K. National Health Service's datasets could be 5 billion (approximately $6.4 billion) per year and deliver around 4.6 billion (approximately $5.9 billion) of benefit to patients per year in potential operational savings for the NHS, enhanced patient outcomes and generation of wider economic benefits to the U.K.."

New Sources Of Patient Data

The amount of patient-based data is also growing due to new technology developments. Wearables are one prominent source of this new data. The Apple Watch, for example, can monitor and track heart rhythm with a level of sophistication that would have been unimaginable only a few years ago. Glucose monitors can be connected to smartphones to support behavioral changes in patients who need help managing their diabetes.

One of the most exciting developments to me is affordable genome sequencing. It was once a process that cost a thousand dollars or more, but one company recently offered it for $199. Access to this data is a very important development for personalized medicine, especially for cancer patients for whom targeted therapies based on genome analysis could mean the difference between life and death.

Data-Centric Business Models

The explosion in healthcare data has led to a number of data-driven business partnerships. Pfizer collaborated with Flatiron Health to use real-world data in an application for FDA drug approval. In another example, a large insurance provider created an app for smartwatches to help members track their actions so they can receive rewards for activities that improve their well-being. There is also a marketplace for anonymous data. Cloud-based HealthVerity Marketplace, for example, lets customers browse and license data from over 50 billion anonymized transactions.

More partnerships and vertical marketplaces for data will surely emerge over time.

Challenges Ahead

While the idea of data-driven healthcare is widely embraced, putting it into practice is not so simple. There are several barriers to widespread use of statistical data as a new weapon in the ongoing battle against disease.

The technical challenges of collecting and analyzing health data are not trivial. One 2010 survey (viaPR Newswire) conducted for a web-based electronic health record (EHR) company found that the average American patient accumulates records from 18 different providers over a lifetime. The data from many of those visits may be in incompatible formats. In my experience, data collected by governments tends to be in silos as well. As a result, I expect that a considerable amount of data integration work will be required before the data is even ready for analysis.

The twin concerns of privacy and security are also major barriers to data sharing. Generally speaking, patients may be willing to share their health data when it is for a good cause -- such as better outcomes for others. However, there is always the risk that such data will be used to discriminate against people with health conditions. In addition, there is the issue of security -- over 13 million healthcare records were reportedly exposed in breaches in 2018 alone. Another issue is that providers may fear losing a competitive advantage by sharing data.

However, none of these are insurmountable barriers. I believe digital data has enormous potential to influence outcomes for the better and to deliver business value. That potential will not go untapped. Patient data will still be extremely important, but I'm sure it will be enhanced by data from external sources in a win-win model.

Read more from the original source:
How We Can Improve The Healthcare Industry With A Healthy Dose Of Data - Forbes

Todays clinical labs are experiencing a shortage of personnel, but the labs themselves cant slow down.

Value-based healthcare puts a premium on delivering patient outcomes, Timea Zsiray, director of strategy and marketing for Beckman Coulters Workflow and Informational Technology Solutions Business, explained during a press conference at AACC 2019. Clinical labs are an essential part of healthcare, as 65 to 70% of [healthcare] decisions are made based on lab data, she explained.

Consequently, labs have to improve turnaround time while delivering accurate results, she added.

Automation is a promising solution. She pointed out that 32 main steps are typically performed in the lab, most of which are performed manually, and addedthat manual processes are "time consuming and error prone. There is "a need to make lab personnels jobs easier.

However, automation is not just the movement of tubesbut also the digital movement of data, Zsiray.

Healthcare professionals who spoke during the press conference all agreed that healthcare systems are experiencing a shortage of well-trained medical professionals. These speakers included Dr. David Koch, associate professor of pathology at Emory University School of Medicine and director of clinical chemistry, special chemistry, toxicology and point-of-care testing at Grady Memorial Hospital in Atlanta; Dr. Steven H. Wong, professor of pathology and director of the clinical chemistry and toxicology core laboratory, and co-director of the clinical and translational mass spectrometry center at Wake Forest School of Medicine; and Robin Ades, senior regional director of operations for Alverno Laboratories.

Said Koch: We dont have enough people going into the clinical lab profession.

Added Ades: Small- and mid-sized labs have the same staffing issues, especially in rural areas where we dont have the pool of applicants as in the past. And efficiency is expected of all labs, regardless the size. Turnaround time expectations are the same despite the size of the healthcare system, she added.

These professionals are hopeful that automation can help fill the gap. Automation makes it possible to deliver high throughput, Wong said.

Automation has been critical to our success at Grady Hospital in Atlanta, said Koch, adding later that automation helps all staff, even part-time and weekend staff. They have to produce the same high-quality result as the Monday-Friday staff.

Automation may also enable labs to maintain staff engagement. Weve found that we needed our techs doing clinical scientific lab work, not mundane tasks such as specimen processing and loading them into instruments, said Ades. Koch agreed: Graduates want to be involved in meaningful work. Getting the result to the doctor that will benefit the patient is the most important, rather than fussing over minutia that could be handled by automation.

If staff is satisfied and happy, they are more likely to stay, said Wong.

However, todays emerging automation solutions mean more than just moving samples around in a lab. Automation can also contribute to efficiency in processing and results delivery. AutomatedIT allows labs"to be more fail safe in terms of labeling and specimen errors, said Ades. AddedKoch: We can rely on IT to auto-validate much of the data.

To support such automation needs, Beckman Coulters newest solution automates sample handling and more. At AACC Beckman Coulter highlighted WorkflowConnect, WorkflowAdvanced, and WorkflowCommand solutions that are designed to meet the needs of small-, mid-, and high-volume laboratories. It also demonstrated its newest total laboratory automation solution, the DxA 5000, which is intended to improve efficiency through several onboard funtions that help identify and address pre-analytical errors, automate labor-intensive and error-prone laboratory tasks, and auto-verify and release normal results.

The DxA 5000 combines sample-processing hardware with informatics from WorkflowConnect, WorkflowAdvanced, and WorkflowCommand middleware. Tubes are bar coded and after being loaded into the system move through centrifugation and other processes. Data is captured on the status of each sample as it moves through processing, and results are captured and transmitted as soon as available.

Automation used to be moving a tube from A to B, explained Dr. Christoph Moellers, vice president and general manager of Beckman Coulters Workflow and Informational Technology Solutions Business. Now, we receive a tube and deliver a resulteverything in between is automated. We used to focus on push mechanismsa tube comes in and we push it down the line. Now we use a pull mechanismwe pull requests to analyzers to maximize operational throughput.

"We didnt have the software in place before to perform that pull, " he added. Now, "we have that connection in the middleware.

Ades appreciates such capability. Its the scalability of the data flow, she said. The middleware piece is important for us to be standardized across our systems.

In addition, the automated system features a minimum amount of failure points in the system to maintain uptime, Moellers said. He said that Beckman Coulter had interviewed 180 customers globally and found that labs are challenged to maintain short turnaround time with consistent results.

Beckman Coulters solutions are also intended to meet the needs of labs of varying size. We believe in automation for all, so we designed the system to be modular, so we can scale it, he said. Mid-sized hospitals dont always have the buying power or the space in terms of footprint.

Beckman Coulters focus on data could also help it meet the needs of both centralized and decentralized laboratories. I am sure whatever direction [trends go], you need a tool to connect the dots and the data. Thats why informatics is so critical, Moellers said.

Added Koch: The key is that the lab houses the data and provides the data to the clinician. Automated solutions help small and large labs and all those in between.

Wong believes that automation could support emerging diagnostics testing such as multiple-panel biomarker testing, personalized medicine, and genomics and enhance the delivery of that information.

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Supporting the Digital Movement of Diagnostics Data - Medical Device and Diagnostics Industry

BANGALORE, India, Nov. 18, 2019 /PRNewswire/ -- Molecular diagnostic screening is used to identify different DNA or RNA sequences, including single nucleotide polymorphism (SNP), deletions, rearrangements, insertions, and others for further detection of the disease. These combined methods, such as genome and proteome, helps examine biological markers at the molecular level. These methods are used to treat various infectious diseases

It is expected that technological advances in molecular diagnostics will drive the market dramatically as they allow for greater precision, portability and cost-effectiveness. The launch of MinION, a compact and inexpensive sequencer for users in point-of-care facilities and small peripheral laboratories by Nanopore Technologies, is expected to fuel market growth.

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Trends Influencing The Molecular Diagnostics Market Share

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Region Wise Analysis Of Molecular Diagnostics Market Share

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Top Investment Pockets

The global molecular diagnostics market is segmented by application into infectious diseases, oncology, genetic testing, blood screening, and others (microbiology, neurological diseases, and cardiovascular diseases).

Infectious diseases projected the highest revenue in 2016, with a CAGR of 9.3% for the forecast period of 2017-2023, owing to an increase in the number of patients suffering from different viral and bacterial infections, such as Human Immunodeficiency Virus (HIV), Hepatitis C virus(HCV), Human Papillomavirus(HPV), Chlamydia trachomatis/ Neisseria gonorrhoeae (CT/NG), and others. Along with the improving healthcare facilities treating these diseases in the emerging nations.

Molecular Diagnostics Market Key Segments

By Product

By Technology

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Global Molecular Diagnostics Market Size was Valued at 5,962 Million US$ in 2016 and is Expected to Reach 10,557 Million US$ with a CAGR of 9.1% by...

Here are the top stories covered by DocWire Newsthis week in the Hematology & Oncology section. This week, a report indicated that where you live impacts your chances of surviving lung cancer, ruxolitinib is associated with worsening cardiometabolic health, and more.

Men with theBRCA2mutation have an increased risk ofprostate cancercompared with non-BRCA2carriers and should undergo regular prostate-specific antigen testing, according to interim research from the IMPACT study, presented at the National Cancer Research Institute 2019 Cancer Conference. The results were also published inEuropean Urology.

In the past decade, newlung cancercases have decreased by 19% and five-year survival has increased by 26%, according to a promising report from theAmerican Lung Association. Despite this,lung cancerremains the leading cause of death in the United States, and the chance of surviving the disease is largely dictated by where a person lives.

Secondary surgical cytoreduction followed by chemotherapy does not extend overall survival (primary endpoint) compared with chemotherapy alone in patients with platinum-sensitive, recurrent ovarian cancer, according to a study published inThe New England Journal of Medicine.

Melanoma of the eye may soon be detected using a simple test, according to a study thatappeared inTranslational Vision Science & Technology.

Ruxolitinib, an oral JAK1/2 inhibitor approved by the U.S. Food and Drug Administration for the treatment of myeloproliferative neoplasms, is associated with worseningcardiometabolic health, according to an article published inScientific Reports.

In case you missed it, more hem/onc headlines are featured below:

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Hem/Onc Roundup: BRCA2 Mutation and Prostate Cancer, Cancer Drug Affects Cardio Health, and more - DocWire News

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The sixth annual Arkansas Bioinformatics Consortium conference is set for Feb. 10-11 at the Wyndham Riverfront in North Little Rock. Its theme is Artificial Intelligence in Arkansas.

AR-BIC is an annual event, but its meant to be a collaborative community of research scientists and practitioners in this field of bioinformatics, said Jeremy Harper, director of communications for the Arkansas Research Alliance.

ARA, headquartered in Conway, is the lead organizer of the conference. The Food & Drug Administrations National Center for Toxicological Research in Jefferson County is a major sponsor.

Harper said conference registration is free and complementary lodging is available, thanks to a $15,000 grant from the FDA and sponsorships that cover what remains of its $40,000-$50,000 budget.

The conference will be held from 1-7:30 p.m. Feb. 10 and from 8:30 a.m.-4:30 p.m. Feb. 11.

AR-BIC was born out of a realization by the NCTRs Division of Bioinformatics & Biostatistics and others that we have a real developing, emerging competency in bioinformatics here in the state and it needed to be nurtured, Harper said. The objectives of AR-BIC, he said, are to:

The first conference attracted 90 attendees, and attendance has been growing since then, Harper said. More than 200 attended the 2019 conference.

The AR-BIC governing board oversees the conference. The board includes representatives from Arkansas State University, the University of Arkansas, the University of Arkansas at Little Rock, the University of Arkansas for Medical Sciences, the University of Arkansas at Pine Bluff, the NCTR and ARA. ARA President and CEO Jerry Adams chairs it. Entities represented on the board provide most of the conferences speakers.

Highlights of the 2020 conference include a new panel composed of ARA Academy scholars and fellows and a theme that is on point, Harper said.

This [upcoming] year is on AI, and theres just been an explosion of growth around AI, he said. The computational requirements of personalized medicine alone, not to mention things like driverless cars and all that, make it a pretty strategic theme.

Harper also said the FDA, a major sponsor, will need AI to do its job, which is to protect human health.

In addition, the topic is timely, he said, because ARA fellow Xiuzhen Huang of A-State recently founded the Arkansas AI-Campus. It is a virtual statewide interactive training program seven institutions are participating in. The program allows researchers to work with global and national experts in machine learning, artificial intelligence and deep learning. Deep learning is the practice of imitating the workings of the human brain in processing data and creating patterns for use in decision-making.

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Conference to Focus on AI in Arkansas - Arkansas Business Online

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Nov 18, 2019--

Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced that results from a number of studies across its growing breast cancer portfolio will be presented at the San Antonio Breast Cancer Symposium (SABCS) on December 10-14, 2019. These data include new results in HER2-positive breast cancer and studies of new molecules in hormone receptor-positive (HR-positive) breast cancer.

For the past three decades, we have remained dedicated to improving outcomes for people with breast cancer, said Levi Garraway, M.D., Ph.D., chief medical officer and head of Global Product Development. This sustained commitment is exemplified by new data for our approved and investigational medicines across the spectrum of breast cancer being presented at SABCS this year.

Key presentations

New data will be presented from a second interim overall survival (OS) analysis of the Phase III APHINITY trial evaluating Perjeta (pertuzumab) and Herceptin (trastuzumab) plus chemotherapy (the Perjeta-based regimen), compared to Herceptin and chemotherapy, as an adjuvant treatment for HER2-positive early breast cancer (eBC). This latest interim OS analysis also includes updated descriptive invasive disease-free survival and cardiac safety data.

Genentech will also present data from the primary analysis of the Phase III FeDeriCa study which evaluated a new investigational fixed-dose combination (FDC) of Perjeta and Herceptin administered as a single subcutaneous formulation in combination with intravenous chemotherapy. The FDC is administered under the skin in just minutes, significantly reducing the time spent receiving treatment and providing people with HER2-positive breast cancer a potential new treatment option for faster delivery of the Perjeta-based regimen.

Data will also be presented from studies in HR-positive breast cancer, including findings from early studies investigating Genentechs pipeline molecules GDC-9545, a selective estrogen receptor degrader, and GDC-0077, a mutant selective PI3K inhibitor.

Overview of Genentech studies to be presented at SABCS 2019

Medicine(s)

Abstract title

Abstract number

(date, time, location of presentation)

HER2-positive breast cancer

Perjeta and Herceptin

Interim OS analysis of APHINITY (BIG 4-11): a randomized multicenter, double-blind, placebo-controlled trial comparing chemotherapy plus trastuzumab plus pertuzumab versus chemotherapy plus trastuzumab plus placebo as adjuvant therapy in patients with operable HER2-positive eBC

Abstract GS1-04

(Oral)

Wednesday, December 119:30 9:45 AM CST

Hall 3

Perjeta and Herceptin

Subcutaneous trastuzumab and hyaluronidase-oysk with intravenous pertuzumab and docetaxel in HER2-positive advanced breast cancer: final analysis of the Phase IIIb, multicenter, open-label, single-arm MetaPHER study

Abstract P1-18-05

(Poster)

Wednesday, December 115:00 7:00 PM CST

Hall 1

Perjeta and Herceptin

Risk of recurrence and death in patients with early HER2-positive breast cancer who achieve a pathological complete response (pCR) after different types of HER2-targeted therapy: a retrospective exploratory analysis

Abstract P1-18-01

(Poster)

Wednesday, December 115:00 7:00 PM CST

Hall 1

Perjeta and Herceptin

Use of pertuzumab in combination with taxanes for HER2-positive metastatic breast cancer (MBC): analysis of United States electronic health records

Abstract P1-18-14

(Poster)

Wednesday, December 115:00 7:00 PM CST

Hall 1

Kadcyla (ado-trastuzumab emtansine)

Cardiac events in patients with HER2-positive MBC who have low left ventricular ejection fraction prior to initiating treatment with ado-trastuzumab emtansine: a retrospective cohort study using electronic health record data

Abstract P1-18-11

(Poster)

Wednesday, December 115:00 7:00 PM CST

Hall 1

Tecentriq (atezolizumab), Kadcyla, Perjeta and Herceptin

Atezolizumab in combination with ado-trastuzumab emtansine or with trastuzumab and pertuzumab in patients with HER2-positive breast cancer and atezolizumab with doxorubicin and cyclophosphamide in HER2-negative breast cancer: safety and biomarker outcomes from a multi-cohort Phase Ib study

Abstract PD1-05

(Poster discussion)

Wednesday, December 115:00 7:00 PM CST

Hemisfair Ballroom

Perjeta and Herceptin

Subcutaneous administration of the fixed-dose combination of trastuzumab and pertuzumab in combination with chemotherapy in HER2-positive eBC: primary analysis of the Phase III, multicenter, randomized, open-label, two-arm FeDeriCa study

Abstract PD4-07

(Poster discussion)

Thursday, December 12

7:00 9:00 AM CST

Stars at Night Ballroom 1&2

Kadcyla and Perjeta

Association of immune gene expression with outcome in the MARIANNE Phase III clinical trial in HER2-positive MBC

Abstract PD5-11

(Poster discussion)

Thursday, December 12

7:00 9:00 AM CST

Stars at Night Ballroom 3&4

Kadcyla and Herceptin

Adjuvant ado-trastuzumab emtansine versus trastuzumab in patients with residual invasive disease after neoadjuvant therapy for HER2-positive breast cancer: KATHERINE subgroup analysis

Abstract P3-14-01

(Poster)

Thursday, December 12

5:00 7:00 PM CST

Hall 1

Herceptin

Palbociclib in combination with trastuzumab and endocrine therapy versus treatment of physician's choice in metastatic HER2-positive and HR-positive breast cancer with PAM50 luminal intrinsic subtype (SOLTI-1303 PATRICIA II): a multi-center, randomized, open-label, Phase II trial

Abstract OT2-02-06

(Poster)

Thursday, December 12

5:00 7:00 PM CST

Hall 1

Kadcyla and Herceptin

Cost-effectiveness of ado-trastuzumab emtansine versus trastuzumab for the adjuvant treatment of patients with residual invasive HER2-positive eBC in the United States

Abstract P6-13-01

(Poster)

Saturday, December 14

7:00 9:00 AM CST

Hall 1

Hormone receptor-positive

GDC-0077

A first-in-human Phase Ia dose escalation study of GDC-0077, a p110a-selective and mutant-degrading PI3K inhibitor, in patients with PIK3CA-mutant solid tumors

Abstract OT1-08-04

(Poster)

Wednesday, December 11

5:00 7:00 PM CST

Hall 1

GDC-0077

A Phase Ib dose escalation study evaluating the mutant selective PI3K-alpha inhibitor GDC-0077 in combination with letrozole with and without palbociclib in patients with PIK3CA-mutant HR-positive, HER2-negative breast cancer

Abstract P1-19-46

(Poster)

Wednesday, December 11

5:00 7:00 PM CST

Hall 1

GDC-9545

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Genentech to Present New and Updated Data for Seven Approved and Investigational Medicines Across Multiple Types of Breast Cancer at the 2019 San...

Why has nobody really 3D printed a heart yet? Will animals also benefit from 3D printing in the veterinary field? How to start a 3D printing lab in a public hospital? And who is Gary? These are just a few of the proposals answered at the latest and fifth edition of the 3D Med Australia Conference, which concluded last Saturday after three days of workshops, lab tours, and lectures at the AAMI Park, a huge Stadium in Melbourne. The event highlighted 3D printing applications in various health areas like presurgical planning in adult and pediatric fields, bioprinting, medical device design, prosthetic and implantable device design, education of trainees and medical students, as well as patient experience, and even 3D printing to support longevity of equipment for helicopter retrieval (from blood warmers to vial containment).It is the largest 3D technologies in medicine conference in Australasia, convened by Jason Chuen, Associate Professor at The University of Melbourne and Director of Vascular Surgery at Austin Health, in Melbourne, and Jasamine Coles-Black, doctor and vascular researcher at the Department of Vascular Surgery at Austin Health and Austin 3D Medical Printing Laboratory (Austin 3D Med Lab). Apart from featuring frontier health innovation in 3D printing, it was attended by most major labs and scientists in this space.

The highly awaited experience showcased The University of Melbournes experience in this space, as a recognized hotspot of medical device innovation. The multidisciplinary nature of frontier technologies in health meant the work presented is a result of the collaboration between doctors, engineers, veterinarians, cell biologists, industrial designers, lawyers, and policymakers.

3D technologies, including 3D printing and augmented reality, are set to radically transform the way we teach, train, plan, rehearse, and perform surgery; and Australia is lining up to be one of the leaders in the field, said Chuen. We are proud to support this by bringing together all of these great minds: from what I can see, Australia, and Melbourne, in particular, will be a major hub of medical technology development, and 3D related technologies will be a key part of this.

Atandrila Das, General Surgeon at Northern Health, Melbourne, presented a world-first case combining 3D visualization with robotic cancer surgery, which was a result of a collaboration between Austin Health and the Peter MacCallum Cancer Centers Department of Surgery doctoral students and surgeons. In addition, Claudia di Bella, Orthopaedic Surgeon, and researcher at Biofab3D in St Vincents Hospitalat The University of Melbourne exhibited her robotics and tissue engineering work.

Additionally, ethics and regulation were a big part of the event, with attendees getting updates from Australian governing bodies like the Therapeutic Goods Administration (TGA), the Department of Health and Human Services (DHHS), and Medical Device Innovation. The TGAs John Skerritt provided leading researchers with an update on the current changes to custom medical device and implant regulations coming in late November. Some of the proposals for change include a medical device production system framework to allow healthcare providers to produce lower risk personalized devices without manufacturing certification and regulation of medical devices with a human origin component as medical devices with a biological component rather than biologicals.

What is wrong with this image? OConnell explains why nobody has really 3D printed a heart yet (Image Credit: Cathal OConnell)

During the talk Dont Print Your Heart Out, facility manager at BioFab3D, Cathal OConnell, dissected the hype from reality and explained why nobody has really 3D printed a heart yet, suggesting it is dangerous to provoke so much buildup in platform technologies and how clinicians, scientists, and reporters need to be careful when delivering their message on medical technologies.

In the original printed heart scientific paper, Israeli scientists describe [] the main focus was to print a square patch of heart cells and blood vessels using a personalized bioink. As a final flourish, the team also printed the cells into a thumbnail-sized, heart shape. The text of the original paper clearly states the printed heart-shaped structure is not a real heart and lacks most of the features required to make a heart work. This is impressive work the cardiac patches may indeed turn out to be an important development in the field. Im more worried about media reports giving the impression that our field of research is far more advanced than it is, said OConnell.

Elizabeth Sigston at the Women in 3D Med Event (Image Credit: Austin 3D Med Lab)

While Blake Cochran, from the University of New South Wales (UNSW), Sydney, introduced Gary, a 3D printed radiologically realistic skull, and Stewart Ryan, from The University of Melbourne Universitys vet school, explored the importance of 3D printing for the training of veterinary surgeons for all creatures great and small, and Ryan should know, he has even performed surgery for a 14-year old tiger at the Melbourne Zoo to remove a cancerous tumor.

As part of the event, the inaugural Women in 3D Technologies networking drinks were held in partnership with the Commonwealth Scientific and Industrial Research Organisation (CSIRO), with Elizabeth Sigston (a leading head and neck cancer surgeon) giving the keynote speech. The conference proved that there is a strong representation of women in STEMM careers across Medicine, Dentistry and Health Sciences (MDHS) in Melbourne.

3D technologies are the natural next steppingstone in the era of personalised medicine, said Coles-Black. Australian doctors, engineers and other researchers need to come together in order to make the most of this new frontier in medicine. Our conference provides a collegiate environment for much-needed multidisciplinary collaboration.

Jason Chuen, Elizabeth Sigston, Frank McGuire, and Jasamine Coles-Black at the 3D Med Conference (Image Credit: Austin 3D Med Lab)

Coles-Black also explained that this conference seeks to bring together experts to solve the often-quoted barriers to the adoption of 3D printing technologies in healthcare settings, such as the lack of technical and regulatory knowledge, perceived costs, and lack of expertise in implementation.

A tour of RMITs Additive Manufacturing Precinct (Image Credit: Austin 3D Med Lab)

In addition, the conference featured a tour of the new MDHS SBS Digital Learning Hub. Other University of Melbourne labs featured through hands-on tours included the Melbourne School of Designs NExT Lab and BioFab3d, Austin 3D Med Lab, and the Australian Research Council Training Centre for Medical Implant Technologies (ARC-CMIT)which launched on November 8. In addition, there was a significant focus on industry, startup and commercialization, and medical device development with representatives from the Medical Device Partnering Program, Stratasys, HP, Evok3D, Kyocera, Leapfrog, Gore, Global3D and Materialise.

Clinicians and engineers need to work together to develop this technology and find ways to implement it effectively and safely. Collaboration is key in this industry, claimed Chuen.

During the occasion, there was a lot of hype about the clinical uses of augmented and virtual reality in presurgical planning, medical student education, forensics, trauma simulation, and to improve hospital systems.

At the Anatomical 3D Segmentation Workshop, in collaboration with Evok3D, an HP 3D Partner in Australia, guests learned more about the end-to-end workflows for the production of 3D printed color anatomical models, which can be used to improve pre-surgical planning, patient consultation, and support medical education. Medical 3D technology for patient care is getting more and more accessible, every day, providing patients personalized treatment based on their scans as point-of-care 3D printing enables manufacturing directly on location.

Promotional booths were a big part of the event, with visitors looking into how Materialise solutions can provide personalized treatment to patients and guidance on setting up a 3D point-of-care facility at hospitals. And Stratasys even chose the 3D Med Conference to launch its J750 Digital Anatomy Printer in the Australasia region.

The last day of the event kicked off with Mia Woodruff, Professor of Biomedical Engineering at Queensland University of Technology (QUT), and Gordon Wallace, a distinguished professor at theUniversity of Wollongong (UOW), talking about the future of bioprinting. Woodruff shared challenges and motivations to translate biofabrication in the hospital of the future, and along with Wallace announced the Biofabrication 2020 event: Biofab by the Beach, set for September 27 through 30, in 2020, proving its all about teamwork, something Wallace was keen on emphasizing during his panel, claiming cross-disciplinary collaboration is key and Australia leads the way as Australians are collaborative by nature. Finally, rounding up the event was Peter Lee, Director of the ARC CMIT, focusing on building the multidisciplinary networks needed to train the new generation of implant engineers. Thats what it was all about at the 3D Med Conference, looking into the future for biotechnology and medical applications that will pave the way for future research and adoption of 3D printing technology.

The entrance to the 3D Med Conference (Image Credit: Austin 3D Med Lab)

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Australias 3D Printing Medical Conference: Focusing on Technology and Teamwork to Advance the Field - 3DPrint.com

New Orleans, LA, November 18, 2019 --(PR.com)-- David Crais, CEO of CMG Carealytics, was invited to the 4th Cross-Industry Innovation Summit held at Johnson Space Center in Houston, Texas last week. An exclusive group of Chief Innovation Officers from NASA, the US Navy, Army, Columbia University Business School, Barnard College, Amazon, Google, Dow Jones, and other global organizations.

Held over three days last week at Johnson Space Center, the Cross Industry Innovation Summit is a deep dive into innovation theory and practice from venture capital, startups, and technology transfer to corporate innovation labs and research and development programs. Exploring the discovery and investigative process with manufacturing, development, and commercialization and adoption of emerging technologies, new ideas, and new program development, these business, social, and government leaders work hands on to share ideas and cultural outlook and framework to bring about advances to their domains and constituencies . This is the fourth year of the program and the fourth year David Crais was asked to participate.

CMG Carealytics, a product management and development firm specializing in scientific, medical, and complex systems and industries, is known as a leader in the innovation and commercialization field. Working with incubators, accelerators, R&D teams, tech parks, venture capital firms, and expert networks, CMG Carealytics founded and led by David Crais continues to spearhead new innovation methods and practices in quality engineering, agile, scrum, lean, buisness analysis, product management, and other sociotechnical methods and in technologies from biotech, regenerative medicine, medical device, digital medicine, personalized medicine, printed electronics, imaging, thermography, and other technologies.

Crais has been engaged in innovation theory since his university education in scientific history and social change up to his development of medical technologies and taking them to market as publicly traded companies, private placements, new product launches, non-profits, and with economic development initiatives.

His participation in the Cross-Industry Summit with NASA is in addition to his work in serving on the Master Plan Task Force with Stennis Space Center in Mississippi, as a board member on the LSU Stephenson Entrepreneurship Institute, an advisor to Nevada State College Entrepreneurship Program, UC Irvine Medical Technology Commercialization Program, and with organizations like the Urban Land Institute, Angel Capital Association, Association for Corporate Growth, and other roles.

Contact Information:CMG CarealtyicsDavid Crais773-398-4143Contact via Emailcraisgroup.comghartman1@hotmail.com

Read the full story here: https://www.pr.com/press-release/799655

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David Crais of CMG Carealytics Invited to NASA Cross Industry Innovation Summit - Benzinga