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Kidney Disease: Early Detection and Treatment

August 23rd, 2015 4:45 pm

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Many Americans know nothing about kidney diseaseuntil it's too late.

"Unlike many diseases, kidney disease often has no symptoms until it is very advanced," says Andrew Narva, M.D., Director of the National Kidney Disease Education Program (NKDEP) a part of the NIH's National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

"For this reason and others, it is important for people to not only become aware of their risk, but also to learn about the steps they can take to keep their kidneys healthier longer. An important step is to get tested."

That testing is even more important for populations that are at higher risk for kidney disease, such as African Americans, adds Dr. Narva.

Your doctor can do very simple tests to check for kidney disease:

How can you tell if you are at risk for kidney disease? Ask yourself these questions:

If you answered "yes" to any of these questions, you are at risk for kidney disease. Now is the time to get tested.

Your health care provider will order two simple tests to check your kidneysa blood test to check your glomerular filtration rate (GFR) and a urine test to check for protein.

Kidney disease is usually a progressive disease, which means that the damage in the kidneys tends to be permanent and can't be undone. So it is important to identify kidney disease early before the damage is done. The good news is that kidney disease can be treated very effectively if it is caught in the early stages. This is very important, since kidney disease also makes your risks for heart disease and stroke higher.

For people who have diabetes, monitoring blood glucose levels is very important. Your health care provider can help you find the right device for doing this if you are diagnosed with diabetes.

Controlling blood pressure is also very important for people with kidney disease. There are several types of medicine that help people keep their blood pressure in a healthy range. Two kinds of medicines, ACEi (angiotensin converting enzyme inhibitors) and ARBs (angiotensin receptor blockers) also help to protect the kidneys.

If one or both kidneys fail completely and the damage can't be reversed, the condition is called kidney failure or end-stage renal disease (ESRD). When this occurs, your kidneys can no longer filter wastes well enough to keep you healthy. The symptoms for ESRD include fatigue, weakness, nausea, vomiting, and itching.

Treatments for kidney failure include dialysis or transplantation. There are two major types of dialysis:

A kidney transplant is an operation that places a healthy kidney in your body. The transplanted kidney takes over the work of the two kidneys that failed, and you no longer need dialysis.

Many researchers are studying kidney disease. They are looking for ways to improve diagnosis, make treatments more effective, and make dialysis and transplantation work better. Several areas of research supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) hold great potential.

NIDDK is sponsoring a major studythe Chronic Renal Insufficiency Cohort (CRIC) studyto learn more about how kidney disease progresses. CRIC is following 3,000 adults for seven years. All study participants have mild to moderate kidney disease, and about half have diabetes.

Researchers think that some CRIC study participants' kidney function will decline more rapidly than others', and that some will develop cardiovascular disease while others won't. The goal of the study is to identify the factors linked to rapid decline of kidney function and development of cardiovascular disease.

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Kidney Disease: Early Detection and Treatment

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