StemCell Therapy

The Re-Brand Premier Regenerative Stem Cell and Wellness Centers, recently rebranded their business from Premier Stem Cell Institute, in response to expanding locations, technology, and treatments. This move reflects the growth and success this company has undergone recently and goals for the future.

PRSC and Wellness Centers President, Kandace Stolz said, This rebrand is the culmination of the years of work weve put into stem cell medicine. Were growing and healing more patients than we ever have before, this new name reflects those accomplishments and gives us room grow. We are so thrilled for this move and cant wait to do even more for our patients going forward.

Premier Regenerative Stem Cell and Wellness Centers will continue to partner with the NFL Alumni Association and treat current and former professional athletes. PRSC remains dedicated to studying stem cell treatment by collecting and tracking data to further stem cell progress and maximize results for all patients. PRSCs commitment to being a leader in stem cell and regenerative medicine is unwavering and will continue to innovate and learn to heal and improve the quality of life for all patients.

About Premier Regenerative Stem Cell and Wellness Centers: PRSC is a leading research and treatment facility in Colorado, providing innovative medicine and therapies for those in pain by harnessing the bodys own natural healing power of stem cells. As team of cutting-edge medical experts, PRSC is dedicated to treating patients by using their own stem cells to heal, improve quality of life, and battle the acute pain of chronic illnesses. Premier Regenerative Stem Cell and Wellness Center locations include Loveland Colorado, Dallas Texas, St. Louis, Missouri, and Jacksonville, Florida. PRSC has plans to expand to other major cities across the United States in the near future.

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Stem Cell Therapy - Premier Regenerative Stem Cell

COLUMBUS For the past year, Dr. Todd Paczosa has been practicing what he calls the future of medicine.

The veterinarian treats his four-legged patients through stem cell therapy.

Im not anti-antibiotic, anti-medicine. I just believe that even in the future of cancer treatment that it is going to come down to your body healing itself, Paczosa said.

The process involves removing fatty tissue from a patient, extracting stem cells, then injecting the cells back into the animal's joints to promote healing.

Paczosa said he researched the treatment for about a decade before deciding to offer it at Redstone Veterinary Hospital in Columbus.

Our body is full of cells that heal. You get cut, your body heals. What we are doing is taking those cells, waking them up and saying, Hey, lets go to work, he said.

Since he started offering stem cell therapy last March, 17 dogs, horses and cattle have used the treatment. One of those patients is Butch, a 9-year-old schnauzer owned by Marge Biester of Columbus that was suffering from a strained ligament and achy joints.

He was really hurting. I had to do something for him, Biester said, adding that Butch wasnt putting much weight on his back leg when he walked.

The treatment was done in January. Butch was put under anesthesia to retrieve the fat tissue. Using equipment in-house, the stem cells were extracted and injected back into the dog that same day.

Paczosa, who has been a veterinarian for 23 years, said the entire process can be done in a day.

Biester noticed results in about two weeks.Butch wasnt doing his three-legged walk anymore and began acting like a more-active, younger version of himself.

Im amazed at how quickly he recovered, she said.

Paczosa said all of the animals he has treated so far have shown improvement.

One of these days, we will have one that doesnt work. Thats just medicine, but we havent had one yet, he said.

The possibility of the stem cell therapy not working can be a turnoff for some pet owners who might find it difficult to spend $1,900 to $2,400 for the treatment at Redstone. If it does work, Paczosa said the therapy is less expensive in the long run than putting an animal on medication for extended periods of time to ease the pain from arthritis.

Other pluses, he said, are that the regenerative therapy isnt as invasive as surgery and anti-rejection drugs don't have to be used since the cells come from the same animal.More than one joint can also be treated at a time and it can eliminate the use of non-steroidal anti-inflammatory drugs.

The biggest risks are putting the animal under anesthesia and infection of the surgical site where the fatty tissue is removed, typically from the shoulder area or abdomen.

Stem cell therapy is practiced at a few hundred veterinary clinics in the country. Redstone works with the animal stem cell company MediVet Biologics and uses that companys in-house technology.

Paczosa said owners have come from other states to use the therapy at his Columbus clinic.

Initial results from the procedure lasts about two years. An option to bank stem cells from a pet is available. A portion of what is taken can be stored in a lab and used again in the future.

For Paczosa's patients, results have been quick and ongoing.

Most owners have seen a dramatic improvement in two weeks. Our first patient is still seeing improvements, he said.

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Stem cell therapy adds pep to pets - Columbus Telegram

Published Feb 15, 2017 at 11:08 am (Updated Feb 15, 2017)

Chris Gildea, with sons Austin and Henry, volunteering at an American Diabetes Association event. Photo provided by Katie Gildea.

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By Meghan Byers

SPARTA For the Gildea family, diabetes isn't just a disease; it's a daily battle. Sparta residents Katie and Chris Gildea, along with their two young sons, ages 3 and 7, will volunteer this June at the American Diabetes Association's upcoming Skylands Tour de Cure, an event which helps fund diabetes research. Chris Gildea, who has type 1 diabetes, has volunteered with the ADA for 10 years. This year, the Gildea family plans to help out at each Tour de Cure event in New Jersey.

"It's a 24-hours-a-day, seven-days-a-week job, living with diabetes," said Katie Gildea. "Diabetes robs you of your ability to lead a care-free life."

The Tour de Cure is the ADA's biggest fundraiser. The Skylands event, which will be held at Waterloo Village, will include both a cycling portion and "fun run & walk" for non-cyclists.

While raising money for a cure is a top priority, Katie Gildea believes that education is equally important, especially when it comes to confronting the social stigma often associated with diabetes.

"A lot of people don't realize that Type 1 diabetes is separate from Type 2 diabetes, and that anyone can have it. A lot of people think it's a choice," she said. "People always tell my husband, 'You look so healthy.' But diabetes doesn't look a certain way. It can affect anyone of any age, any lifestyle."

Chris Gildea, who works at Becton-Dickinson, a company that provides diabetes care products, enjoys an athletic lifestyle despite his disease. "My kids think he's a superhero," said Katie Gildea. "He always tells them never give up, never surrender, and that's how we are with this never give up, never surrender."

According to the ADA, 1.4 million Americans are diagnosed with diabetes each year, and approximately 1.25 million Americans have type 1 diabetes. In 2010, diabetes was the seventh leading cause of death in the United States.

"When you have something like this that can affect your children," said Katie Gildea, "you'll do anything in your power to rid the world of it."

The Skylands Tour de Cure will take place June 4 at Waterloo Village in Stanhope, with a kickoff event taking place on March 23 at Czig Meister Brewery in Hackettstown.

More information and event registration is available at http://www.diabetes.org/skylands, and anyone interested in volunteering can email Katie Gildea at katiehug@hotmail.com.

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Sparta family raises diabetes awareness - The Sparta Independent

This on-line color vision test consists of four cards from the popular color vision test "Color Vision Testing Made Easy". Try and find a circle, star, and/or a square on the Demonstration Card, Card # 1, and Card #2. Try and find a dog, boat, balloon or car on Card # 3. You only have 3 seconds to give the correct answer on each card.

Try to find a circle, star, and/or square on the Demonstration Card

Card # 1 - Try and find a circle, star, and/or square in 3 seconds.

Card # 2 - Try and find a circle, star, and/or square in 3 seconds.

Try and find a dog, boat, balloon, or car (as shown in the below demonstration card) on Card # 3.

Important Disclaimer: Due to the fact there are so many different monitor screens displaying different colors, the accuracy of this "on-line" version of "Color Vision Testing Made Easy" is limited. This webpage is for "screening" purposes only, not a "diagnosis". For a diagnosis, you should see your vision care professional and be given the complete test using all 14 plates of "Color Vision Testing Made Easy" under controlled testing conditions and the proper lighting. You can order the book "Color Vision Testing Made Easy" by clicking on the below picture. Please let the distributor know you were referred by Dr. Waggoner.

Click here if you want to continue testing for colorblindness by taking another popular color vision test like this one called the Pseudoisochromatic Plate Ishihara Compatible (PIPIC) Color Vision Test 24 Plate Edition. It uses numbers instead of objects.

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ColorVisionTesting | Colorblind

Dupe Ademola Popoo la, anOphthalmologist with the University of Ilorin Teaching Hospital (UITH) said as parts of efforts to prevent and curtail blindness among children in Kwara State, 2500 children have been examined.

Popoola made this known on Wednesday in Ilorin, during a visit of Kwara first lady and medical personnel to the Children Hospital at Centre Igboro in Ilorin.

According to her, the state government has enacted law that makes visionscreening compulsory for children from zero to five years. Adding that because of the effort of the state government, a foundation; the USAID has shown interest in the project where they donated some equipment worth thousands of dollars.

Popoola said: 2500 children had so far been examined and some referral has been made to General Hospital in the state. However, four children were diagnosed with blindness due to premature birth.

The Ophtalmologist pointed out that a survey of 100 blind people carried out in the state suggested that, seven out of 10 were blind from childhood,while being hidden in that condition, till they are old enough to come out to begfor a living.

Some years back, Nigeria rose to the challenge of fighting deficiency in Vit. A and measles among children and they were successful.

Four health facilities have been designated as centres for the vision screening of children, these centres would also act as training of staffs and centres for prevention of blindness and enhancement of sight. she explained. Popoola also said that the programme will capture older children to be examined.

In her address, Omolewa Ahmed, the wife of Kwara State Governor has advocated enactmentof Law that will enforce all mothers to take their children to hospital for vision screening before enrollment in government schools.

The Governors wife who is Founder of Life Empowers Anchors Hope (LEAH) encouraged mothers to take their children to immunization centres and as well undergo vision screening as it is free of charge. Ahmed, who said the visit was embarked upon to influence immunization on children and vision screening, stated that all ministries in the state would be made to key into the programme for Kwara children to ensure preventable blindness.

Vision is important and we must ensure that out of negligence or ignorance our children are not exposed to blindness when we can take them for screening and get help, she said. She noted that some of these cases of blindness are avoidable, saying a child that is blind in young age will not havea qualitative life.

Ahmed also revealedthat recently over 200 blind citizens were empowere and N150,000 cheque was given to them each to help them in their trade. The Governors wife was shown the newly acquired vision screening equipment and how it operates.

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Blindness: UITH examines 2500 children in kwara - BusinessDay ... - BusinessDay

Could bionic eyes restore sight to the blind and give the U.S. military super sight?

Bionic implanted eyeballs, Star Trek-style visors, telescopic contact lenses ... these are just a few of the many exciting projects underway to both restore and provide enhanced sight.

Significant strides have been made in tech that will restore and transform lives - replacing white canes, service animals, braille machines and more for the visually impaired.

There has been a lot in the media about prosthetic breakthroughs for U.S. veterans, but what about vision? Last year the Blinded Veterans Association told the House and Senate Committees on Veterans Affairs that there are an estimated 131,580 legally blinded veterans in the U.S., citing data from the Depatment of Veterans Affairs.

THE 5 COOLEST MILITARY INNOVATIONS OF 2016

Technology is being increasingly harnessed to overcome blindness. So far, much of the key progress has been restricted to restoring sight for those with a specific type of visual impairment in particular retinitis pigmentosa an inherited condition that involves the loss of cells in the retina and causes a decline in vision.

BIONIC EYE IMPLANTS

One of the first and most promising bionic eyes is the Argus II made by Second Sight, which is geared toward patients with retinitis pigmentosa.

The system has two parts: a very high tech retinal implant and a camera mounted on eyeglasses or shades. The bionic eye is surgically implanted in, and on, the eye. It has an antenna, an electronics case, and an electrode array.

The camera processes what it sees and sends it to a small computer that the person wears. The data is processed and translated into instructions that are sent wirelessly to the antenna in the implant.

MARINES GET GROUNDBREAKING, UNSTOPPABLE NEW RIFLE MAGAZINE

The retinal implant has 60 electrodes in it. These electrodes provide information to the optic nerve and the optic nerve relays the data to the brain. The optic nerve understands this data as shapes, light and movement.

This vision is not yet like normal sight and it will not restore vision to 20/20. But with Argus II, folks who were once sightless can see in black and white they can read a book and see their homes and loved ones for the first time. More advances are in the pipeline for Argus II to restore color as well as resolution and brightness.

Argus II bionic eyes require functioning retina so many, including many visually impaired veterans, cant take advantage of that tech Second Sights Orion technology could be the solution.

PLUGGING INTO THE BRAIN

By skipping the optic nerve and directly plugging into the visual cortex, Orion could hold enormous potential for veterans who have visual impairment due to trauma.

'STAR TREK'-STYLE SURVEILLANCE DRONE FOR THE US MILITARY

In fact, this approach could potentially help those blinded by cancer or glaucoma.

This new device bypasses the retinal layer and implants electrodes directly onto the visual region of the brain.

Second Sight announced a major breakthrough for its Orion I project late last year. In a trial at UCLA, the very first of these devices to directly plug into the brain, a wireless visual cortical stimulator, was implanted in a human subject. The test was a success and restored vision to a 30-year old patient with no major side effects.

STAR TREK-STYLE VISOR

Ever seen Star Trek? One American company has created a sort of real-life version of character Geordi La Forges visor.

'STAR WARS'-STYLE SPEEDERS COULD CARRY US TROOPS

With the eSight 3 device, the wearer can see full-color video images without a time lag. Wherever the user looks and whatever he or she looks at, the high-speed, high-def camera captures it for them.

Advanced algorithms are used for the video feed. The video is then displayed on two screens in front of the wearers eyes. The video image is provided in a way that overcomes their vision loss.

eSight isnt a cure-all at this point. If the retina damage is too severe, then it may not work. It tends to be more helpful with macular degeneration, for example, than glaucoma. The company says the technology has about a 50 percent chance of working with all conditions.

GIVING SOLDIERS SUPER SIGHT

Advances in this field are also creating the potential to give US warfighters super vision.

HOW F-35A FIGHTER PILOTS ARE HARNESSING HIGH-TECH 'SEE-THROUGH' HELMETS

One exciting example is a new contact lens funded by DARPA, and made by cole Polytechnique Fdrale de Lausanne, that gives the wearer the ability to zoom like a telescope.

The scleral lens has thin aluminum mirrors built into it that work with special liquid crystal glasses. These glasses are connected to an electronic system.

Think Mission Impossible. If you blink your right eye, then it allows magnifying but if you wink your left then the vision is normal. If you blink normally, it doesnt trigger the magnifying mode.

In addition to the contact lens, other projects have made great headway. Even Second Sight bionic eyes can see in IR with a specific input device.

NEW TECH MAKES TANK ARMOR 'SEE-THROUGH'

Augmenting soldiers with vision-enhancing tech could provide advantages for ground troops and special operations in particular. Warfighters could switch between seeing in night vision, infrared, thermal, zoom, telescopic and more. Whether worn or implanted, it would provide enhanced capabilities that remove the weight of carrying optics and the time lost shifting optics by switching instead at the speed of thought.

Just one specific illustration of how helpful this could be is explosives. If the amazing advances in explosive detection could be miniaturized and adapted for military bionic eyes, then warfighters with enhanced vision could scan and spot these hidden IEDs before they could strike putting an end to injury and death due to IEDs.

Meet a Green Beret who was blinded in combat, but still serves, shoots with remarkable accuracy and explored Antarctica with Prince Harry at Tactical Talk this week.

Allison Barrie consults at the highest levels of defense, has travelled to more than 70 countries, is a lawyer with four postgraduate degrees and now the author of the new book "Future Weapons: Access Granted" covering invisible tanks through to thought-controlled fighter jets. You can click here for more information on FOX Firepower columnist and host Allison Barrie and you can follow her on Twitter @allison_barrie.

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'Bionic' eye on the future: From 'Star Trek' visors to 'Mission Impossible' contact lenses - Fox News

Seoul, Feb 17 (PTI) The gene editing tool CRISPR-Cas9 may be delivered directly into the eye to treat age-related macular degeneration (AMD) efficiently and safely, a new study has claimed.

AMD is a form of blindness, common in Caucasians, which causes distorted vision and blind spots.

Scientists at the Institute for Basic Science (IBS) in Korea used CRISPR-Cas9 in performing gene surgery in the layer of tissue that supports the retina of living mice.

The most common retinopathies causing blindness are retinopathy of prematurity in children, diabetic retinopathy and AMD in older adults.

In these diseases, abnormally high levels of the Vascular Endothelial Growth Factor (VEGF) are secreted. In AMD, VEGF causes the formation of new blood vessels in the eyes but also leads to leakages of blood and fluid into the eye, damaging an area at the center of the retina called macula.

Injections of anti-VEGF drugs are the most common treatment against AMD, but at least seven injections per year are required, because VEGF is continuously overexpressed by the cells of the diseased retinal pigment epithelium.

Instead of such invasive treatments, scientists believe that gene therapy with the third generation gene editing tool CRISPR-Cas9 could improve the situation.

The injections tackle the effects, but not the main cause of the problem. By editing the VEGF gene, we can achieve a longer-term cure, said KIM Jin-Soo, Director of the Center for Genome Engineering at IBS.

CRISPR-Cas9 can precisely cut and correct DNA at the desired site in the genome. The system works by cutting DNA at a target site, in this case, inside the VEGF gene.

Two year ago, IBS scientists proved that a pre-assembled version of CRISPR-Cas9, or Cas9 ribonucleoprotein (RNP), can be delivered to cells and stem cells to modify target genes.

The pre-assembled complex works rapidly and degrades before the body has time to build up an immune response against it.

In this study, the team successfully injected CRISPR-Cas9 into the eyes of a mice model with wet AMD and locally modified the VEGF gene.

Initially they found that the delivery of the pre-assembled CRISPR-Cas9 complex is more efficient than the delivery of the same components in a plasmid form.

Secondly, the complex disappeared after just 72 hours.

Scientists assessed the whole genome of the animals and found the CRISPR-Cas9 complex modified only the VEGF gene and did not affect other genes.

The progression of the eye disease was monitored by looking at choroidal neovascularisation (CNV), the creation of new blood vessels between the retina and the sclera a common problem of wet macular degeneration and researchers found the CNV area reduced by 58 per cent.

Moreover, a likely side effect, namely cone dysfunction, that takes only 3 days to show in these mice, did not occur a week after the treatment.

The study was published in the journal Genome Research.

This is published unedited from the PTI feed.

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Gene editing surgery may prevent blindness: study - India.com

Date published: Friday 17th February 2017 10:45

Before wrapping up our series, I want to revisit an example from last week, for two reasons: 1) it shows the value of Expected Goals, and 2) it shows that even stats-conscious people (in this case, me) can miss the main point.

Last week we looked at the Crystal Palace Sunderland game, which finished 0-4, but 1.6 0.9 in expected goals. I noted that the xG totals were misleading, because Sunderland had scored several not-so-easy chances, then sat back and let Crystal Palace attack. What I should have added was that the xG were in one sense not misleading at all: they showed that Sunderland won big not by brilliant overall play, but by brilliant finishing. And as weve seen several times in this series, you cant rely on brilliant finishing to carry you for very long.

In other words, Sunderlands 0.9 xG tells us that as decisive as the victory was, it didnt change one of their underlying problems: the failure to create good chances. The next week against Southampton, one of the best defensive teams in the league, they wound up with a minuscule 0.2 xG and, unsurprisingly, no goals at all.

And now to wrap up, because the counter says F365 has let me spend over 10,000 words on football stats. But to say weve only scratched the surface is putting it very mildly. Football stats are a burgeoning field, and literally every day there are new ideas worth reading about. New measures are developed on a regular basis, many of which we havent even had the time to mention here. The one thing you can be sure of with football stats is that therell always be something more to learn.

Even better, many of the chief practitioners show and discuss their work publicly, and are more than willing to answer questions and share their thoughts. There are a number of excellent writers in the field, who can explain things far more complex than weve mentioned here, and write far more entertainingly doing it. There are also several good analytics podcasts, where you can hear intelligent people kick around interesting ideas, and have fun doing so.

Wheres the best place to go for football analytics? Surprisingly, its Twitter. Virtually all the experts have accounts remarking on current developments, and all provide links to the longer articles with the detailed analysis thats the meat of the subject. Here are links to some of the most prominent figures in the field, all of whom are worth reading on a daily basis:

Michael Caley, Paul Riley, Simon Gleave, Ted Knutson, James Yorke, Ben Pugsley, Mark Thompson, Mike L. Goodman, Thom Lawrence, Ben Mayhew, David Sumpter, Sander, and Dustin Ward.

Theres also a great site called Statsbomb which, although not as active as in the past, has an outstanding archive of articles. Its the site that first got me interested in analytics.

I assume anyone whos read this far has some interest in stats. But for all that they show us, we have to remember they dont have all the answers. Last year was a case in point: the stats kept saying that Leicester would fade. Around the middle of last season, having watched all the games to that point, and looked closely at the stats, I decided with self-important assurance that Spurs would win the title.

But it gets funnier. At a gathering of statisticians around the same time, somebody took an informal poll of about ten attendees on who would win the title. Going by Expected Goals and other numbers, half of them picked Arsenal.

So theres a condition which we can call statistical blindness. Stats people sometimes say Trust the numbers, not your eyes, but your eyes are there for a reason. Stats are an aid, sometimes an excellent aid, to understanding. They can tell you what to look for. But you still have to look, and you have to spot the things that stats cant reach.

To close, thanks to all the people who had kind things to say about this series. And thanks to those too who had less than kind things, because they remind you what really counts. Football is first, last, and always about love. I loved the game for almost fifty years before I even suspected there could be such a thing as football stats, and if all the numbers disappeared tomorrow, Id love it just as much. But for me, stats engage the mind in all sorts of fascinating ways. And when the mind and heart go together, theres a special kind of joy.

Peter Goldstein

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'Statistical blindness', and importance of numbers - Football365.com

Jordans Jack Friedges is putting one foot in front of the other to help find a cure for arthritis.

Friedges will be participating in the annual Walk to Cure Juvenile Arthritis event at the Mall of America on Saturday, March 4 at 9 a.m. The event features a three-mile and one-mile course.

Friedges has also been named the Young Adult Honoree for this years event.

The cause is personal for Friedges, who was diagnosed with juvenile idiopathic arthritis (JIA) in 2014. Friedges was able to keep his arthritis under control with the help of medication, and he continues to be a three-sport athlete at Jordan High School in football, basketball and baseball.

I joined the Arthritis Foundations Walk to Cure Arthritis to help the more than 50 million Americans and 300,000 children with arthritis live better today and to keep the Arthritis Foundations promise of finding a cure for tomorrow, Friedges wrote on his donation page.

Your support provides people with arthritis life-changing resources and information to manage their disease and improves access to the critical medications they need to live full, healthy lives. The impact of your donation doesnt stop today, it also helps fund cutting-edge research to identify better treatments and a cure, Friedges added.

Friedges has set a goal of raising $5,000 for the event. As of Monday, he had raised $1,515 through his fundraising site, which can be found at http://bit.ly/2lIhosf

The Jordan Basketball Association will be hosting a fundraiser to support Friedges during the Hubmen and Jaguars basketball games on Tuesday, Feb. 21.

The girls game against Waseca will start at 6 p.m., and the boys will play Holy Family at 7:45 p.m.

Find a Cure for Juvenile Arthritis Jacks Journey bracelets will be on sale for $2, and all proceeds from the half court toss at both games will benefit the Juvenile Arthritis Foundation on Friedges behalf.

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Jordan youth walks to cure juvenile arthritis - SW News Media

Takeda and TiGenix have presented 52-week data on their allogeneic expanded adipose-derived stem cells in Crohns disease patients with treatment-refractory complex perianal fistulas. The data show the Cx601 stem cells continue to outperform placebo one year after administration.

TiGenix presented the 24-week data from the successful phase 3 trial back in 2015, sparking a surge in its stock price and setting it up to land a deal with Takeda. Last year it followed up with the release of a first look at 52-week results confirming the efficacy outcomes seen in the earlier data drop.

Takeda and TiGenix have now shared another overview of the 52-week data at the 12th Congress of the European Crohns and Colitis Organisation (ECCO). The abstract includes treatment-related adverse event data that were absent from TiGenixs original release, but included in subsequent presentations.

Those 52-week data confirm the positive safety profile seen in the 24-week results. The rate of treatment-emergent adverse events was lower in the Cx601 cohort than the placebo plus standard of care arm at both time points. The same is true when only serious adverse events are analyzed.

The safety results complement the previously-released efficacy data. Among the 62% of patients who completed the 52-week follow-up, the results were comparable to those generated after 24 weeks. In the Cx601 arm, 56.3% of the modified intention-to-treat (mITT) population achieved combined remission after 52 weeks, compared to 51.5% after 24 weeks. The respective figures for the placebo cohort are 38.6% and 35.6%. The mITT population included all patients to undergo at least one post-baseline efficacy evaluation.

These data highlight that the efficacy and safety of a single administration of Cx601 were maintained during one year of follow up, TiGenix CMO. Marie Paule Richard said in a statement. It is important to also note that the definition of combined remission used in the ADMIRE-CD study, which includes both clinical and radiological assessment by MRI, is more stringent than the criteria commonly used in previous large scale, randomized clinical trials evaluating perianal fistulas in Crohns disease, based only on clinical assessment.

Relapse rates in the Cx601 group were rarer, too. Three-quarters of participants who responded to Cx601 after 24 weeks made it to 52 weeks without relapsing. The number falls to 55.9% among the placebo cohort.

TiGenix is hoping the data will prove compelling enough to secure a regulatory approval in Europe later this year. In parallel, TiGenix is setting up another phase 3 trial designed to deliver data to support approval in the U.S.. TiGenix expects the trial to start later this year.

Shares in TiGenix traded up 4% shortly after the stock exchange in Brussels opened for the day.

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Takeda, TiGenix stem cell therapy shows sustained effect - FierceBiotech

Stem cell therapy treatment gives new lease of life to 5-year-old Jamshedpur February 17, 2017 , by Desk 60

Ranchi : Till very recently, it was believed that brain damage is irreversible. However, now with emerging research; we understand that it is possible to repair the damaged brain tissue using cell therapy.

Again, today there are still many people in India who have not preserved their stem cells through cord blood banks. For all those patients, who have lost their hopes in finding a new treatment for neurological related disorders, adult stem cell therapy offers a new hope for such kind of patients.

Dr Alok Sharma, Director, NeuroGen Brain and Spine Institute, Professor and Head of Neurosurgery, LTMG Hospital & LTM Medical College, Sion said Stem cell therapy is emerging as one of the newer treatment options for conditions like Autism, Cerebral Palsy, Mental retardation, Muscular Dytrophy, Spinal Cord Injury, Paralysis, Brain Stroke, Cerebellar Ataxia and Other Neurological Disorders. This treatment has the potential to repair the damaged neural tissue at molecular, structural and functional level.

Dr. NandiniGokulchandran, Deputy Director, Neurogen Brain and Spine Institute saidStem Cell Therapy (SCT) done at NeuroGen Brain and Spine Institute is a very simple and safe procedure. Stem Cells are taken from patients own bone marrow with the help of one needle and are injected back in their Spinal Fluid after processing.

Since they are taken from the patients own body there is no rejection, no side effects, hence making SCT a completely safe procedure.

Today, we are presenting a case study of Ranchi based 5 yrs old Master Dhairya Singh. He is a known case of brain damage due to lack of oxygen but not during birth. Dhairya was born in a normal manner, cried immediately after birth also his birth weight was appropriate.

There were no immediate post-natal complications reported. Dhariya was a normal child till the age of one and half years old. Then one day he suffered from an episode of pneumonia for which he was hospitalized for 6 days.

Last updated:Friday, February 17, 2017

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Stem cell therapy treatment gives new lease of life to 5-year-old - Avenue Mail

Spotting the illness that can cause sudden blindness - BBC News BBC News Every year in the UK, 3000 people's sight is damaged by a condition called giant cell arteritis. Dr Saleyah Ahsan explains what to look out for. and more »

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Spotting the illness that can cause sudden blindness - BBC News - BBC News

It was such a privilege to be part of the 2012 Paralympics and to witness what felt like a breakthrough at that time. Disability was no longer swept aside in subdued tones but talked about openly. Even celebrated! It was amazing to see the pride everyone had in the athletes and their incredible achievements.

Now, more than four years later, another amazing Paralympics has passed and both events have left a much improved legacy. But sadly, there remains an awkwardness surrounding disability. Especially, from my perspective, of visual impairment. I hope it's true that more people have now been encouraged to approach the person in a wheelchair. But my personal experience tells me that there is still a vast lack of understanding when it comes to blindness.

I have always been a passionate advocate of open discussion and the promotion of visual impairment awareness and this is clearly what John Hull has done with his remarkable film. I've seen and read much that tried to make visual impairment understood by the sighted world, but I have never found any to be as effective in humanising visual impairment as the BBC's Notes on Blindness.

The onset of my gradual sight loss began when I was five, bringing with it a huge range of emotions to deal with - along with people's reactions. I had to come to terms with my sight loss as I entered my teenage years. I do not appear visually impaired, and at times I have been treated as an imbecile, or a fraud.

So hearing John Hull explain, in his own words, the sensation of going blind and the internal battles that come with it was incredibly moving for me. As John lost his sight, so many of his stories and moments resonated deeply. I understood when he said "Every time I wake up, I lose my sight", describing how he had more sight in his dreams. I often find I wake feeling sure that in my dream I was fully sighted, like when I was a child. I was so pleased to hear it so eloquently described by John.

When John describes a strange incidence of meeting a faith healer, who told him that his sight was 'dependent on his will', this felt familiar too. It is one of the more extreme reactions to finding out someone is visually impaired, but actually far more common than you think. I myself have been 'healed' three times!

But this and more common suggestions like "Can't you just wear glasses?" remind me how important it is to keep pushing to create an awareness of visual impairment.

I was thrilled to see this insightful programme and feel the BBC have managed to create something that makes visual impairment relatable. I wish that, rather than making uninformed comments people would feel free to actually ask about the extent and nature of my condition and John Hull has helped to open that door.

It showed the daily practical battles we fight - which for John, was being unable to access books and data in an accessible format, and for me include being unable to drive to fetch a pint of milk, or the fact that reading takes me four times as long as my fully sighted counterparts. And it evocatively highlights how people of all ages can struggle with accepting their visual impairments.

Over a third of older people living with sight loss suffer with depression, which is an issue not often discussed or considered. And more than two million people in the UK live with sight loss. That's 1 in 30, and the figure is rising.

But I was pleased that the film also showed really positive things that many with disabilities will understand - like their relationships with family and friends. When an able-bodied person is married to a disabled person, it doesn't mean that they take the roles of 'carer' and 'patient'. It was incredibly refreshing to see the marriage between John and Marilyn as a partnership - often how it is in real life.

John completed his film with a simple quote, which I'd like to share to complete this blog "To gain our full humanity blind people and sighted people need each other."

*** Notes on Blindness will be on BBC Four, Thursday 16th February, 9pm. Notes on Blindness will be shown with a choice of viewing experiences for the visually impaired audience, available for the first time across BBC Four, Red Button and BBC iPlayer.

A version with enhanced sound will be available from 9pm tomorrow. Find out more about the versions here.

Excerpt from:
My Notes On Notes On Blindness - Huffington Post UK

Blogs | Feb. 15, 2017

Arizona Woman's Blindness Miraculously Cured Through St. Charbel

Within 48 hours after visiting the relics of St. Charbel, her eyesight was completely restored to 20/20 vision. The remarkable and sudden healing was confirmed later by several physicians.

The joy of a Phoenix parish is spreading along with thenews of 30-year-old parishioner Dafne's Gutierrez'scomplete cure of blindness.

The reported miracle of the wife and mother of three is bringing people from around the country to visit St. Joseph Maronite Catholic church in Phoenix, Arizona.

When she was just 13 years old in 1999, Dafne was officially diagnosed withthe medical condition, idiopathic intracranial hypertension (IIH). One effectof thiscondition can be anothercondition called papilledema, where the pressure in the brain is greatly increased. This pressure affectsthe optic nerves, which in some cases such as Dafne's eventuallyresults in complete blindness.

The various medications and treatments which were tried for Dafneall failed. In 2014 theeyesight in her left eye deteriorated dramatically. Her physicians tried two separate surgeries, installing different types of shunts in an attempt to drain and reduce the pressure in her brain, butthese too failed, leading to complete blindness in her left eye. Meanwhile the sight in her right eye was also deteriorating, and she was declared legally blind. She was soon in total darkness, saying in 2015 that she could look directly at the sun and not see any light whatsoever. She also experienced "vise-like" headaches, seizures, tinnitus (ringing in the ears), vomiting, and dizziness. Her doctors declared her blindness to be "permanent and medically irreversible."

Dafne's blindness left her unable to care for her three young children, which completely broke the young mothers heart. On January 7, 2016, "so as to not be an additional burden on her family", she was approved for admittance to a nursing home, because "she could not take care of herself or her children, due to her blindness and seizures", and was scheduled o be admitted soon. "What hurt me the most was not being able to see my children again," she said.

Around the sametime last January 2016, Dafne heard a Spanish radio news report that the first class relics of St. Charbel (or Sharbel) Makhlouf were on a pilgrimage honoring the Lebanese saint's 50th beatification anniversary, and were going to be coming to a nearby church St Joseph Maronite Catholic Church in Phoenix for the weekend of Jan. 16-17.

Neither Dafne or her family had ever heard of this saint. Yet interestingly, later that same day Dafne's sister-in-law called and told her she'd seen an announcement about the visit of the relics, and suggested Dafne and her husband go with her. So theblind mother of three was taken to visit the bone relics of miracle worker St. Charbel during a special veneration and healing service at St. Joseph Church.

Dafne prayed on the way to the church."Please God heal me if not for me, then do it for my kids!I'm tiredI'm tired of going to You praying and asking You to heal me...I am giving in. If You don't want to do it for me, then do it for my kids. That is the way I went in [to the Church] I'm giving in to You. Do it for my kids"

Once at the Church she prayed to God, and then to St. Charbel: "I don't know who you are, but please help me."

After Mass celebrated by parish priest Fr. Wissam Akiki, and the veneration of St. Charbel's relics, her sister-in-law helped her to the confessional. Fr. Akiki was told about her blindnessand blessed her with holy oil touched to the first-class relic of St. Charbel, praying specifically for her to be cured. "I put my hand on her head, then on both eyes, and I asked God to heal her through the intercession of St. Charbel. Fr. Wissam told her that he would be praying for her and that he believed her vision would be restored. Dafne said she "felt very strongly that someone was standing next to me on my right side." Afterwards the priestsaid to Dafne's daughter: "Don't worry, your mom will see again."

After the prayers and blessing with the relic, Dafne asked her sister-in-law, "Who was that standing next to me, on my right side?"Her sister-in-law said,"There was no one standing next to you other than Fr. Akiki." To this day, Dafne is not sure who was standing next to her at that moment, but is sure"someone" was there.

"From that moment" Dafne's stated "I started to feel different. I can't explain it but my body felt different". The next day, Sunday January 17th, 2016, she again went to St. Joseph Church for the 3:00 p.m.Mass and to once again venerate the relic of St. Charbel.

That same Sunday evening at 4:00 a.m. she suddenly awoke with her eyes burning. "They were like burning really burning," and her head hurt "like after an operation." She woke her husband upexclaiming that her eyeswere burning. He asked how that was possible since she had no sensation in her eyes. He then put his hands on her eyes and noticed they felt hot and he said, "They are vibrating and moving" and he also noticed a strong smell like "burning meat". Dafne then realized that she could actually see her husband very vaguely like a shadow. She shouted, "I can see you! I can see you with both of my eyes! I started crying... I wiped my eyes and then opened them again to see if I really could see, and I could."

"I could not believe it. I did not want to close my eyes, she stated afterwards in an interview. My children were shouting: Mom can see! God healed mom!

Within 48 hours (precisely three days after her weekend visit to venerate the relics) her sight was completely restored to 20/20 vision. The remarkable and sudden healing was confirmed that day by an ophthalmologist, and later by several other physicians.

In a statement, Doctor Anne Borik, D.O. stated:

Medically speaking, what is interesting and what captured my interest in this [case] is that you don't see resolution of vision in 48 hours from a long standing optic nerve problem such as Dafne had. My job as a medical physician is to try to find out how this happened medically. We discussed this case with a neuro-ophthalmologist, and also an outside consultant reviewed the entire case, and basically there is no [medical] explanation how Dafne Gutierrez's vision was one day completely blind, and then 48 hours later was restored to normal ...And so based on this information, we as a medical community in reviewing this case cannot explain this medically.

At the very least, the physicians felt that even if she had regained some of her eyesight, there should have been some permanent damage and vision loss in at least her left eye, for that eye had been affected for twoyears. It is expected that there should be at least some optic nerve damage, and that there is simply no medical explanation for a complete restoration of 20/20 vision in both eyes.

"Faith and confession" is what Dafne Gutierrez continues to repeat time and time again when asked about her healing. "I was desperate when I walked into St. Joseph Maronite Catholic Church. Ifelt like God never heard me before, but this time was different, just different. For me to be able to see and read the papers [medical reports] that say that I would never be able to see again...It is such a blessing!"

Exactly one monthafter Dafne's sight was restored,a special Mass of thanksgiving and blessing with the holy oil of St. Charbel took place at St. Joseph Church on February 18, 2016, and was presided by Bishop Abdallah EliasZaidan, Maronite Catholic bishop of Los Angeles, California.

Daffne spoke tothe crowd who had gathered to give thanks to God for her healing through the intercession of St. Charbel: "All the doctors have said: 'There is no explanation'.....God healed me."

In an interview on YouTube, she encouraged everyone: "I just want to keep on telling everybody; Don't lose faith. God does exist. Just have faith ... [go to] confession. Don't lose hope."

Sr Charbel Makhlouf (1828-1898) was a Maronite Catholic monk from Lebanon who died on Christmas Eve at age 73. He spent the last 23 years of his life in a rugged cabin in complete solitude, with poor heat and the bare necessities of life, and was known for his practice of penance and mortifications, eating very little and sleeping on the ground.

Three days after his death he was buried in the monastery cemetery, and for the next 45 nights his tomb was surrounded by a dazzlingly bright light. As the days passed this phenomenon was witnessed by an increasingly large number of local villagers who informed the religious Maronite monastery, none of whom could provide an explanation. Permission was sought from the ecclesiastical authorities for the monks body to be exhumed. Four months after his death permission was obtained, and upon the exhumation his body was found to be completely incorrupt, even thoughhe had been buried in the ground without a casket.Charbel was given fresh clothing before being placed in a wooden coffin in a corner of the monasterys private chapel.

Soon a strange liquid was found exuding continually from the casket, coming from the pores of his body. Described as a mixture of fluid and blood, it continually flowed from his remains day and night. Soon, a local custom began where pieces of cloth soaked in this fluid were soon being distributed as relics, and were being credited with effecting cures. To this day this custom of "holy oil" touched to the relics of St. Charbel used as a blessing is still a very common practice of the faithful, as was used in Dafne's healing.

Read the rest here:
Arizona Woman's Blindness Miraculously Cured Through St. Charbel - National Catholic Register (blog)

A child with nodding syndrome waits for treatment at an outreach site in Uganda's Pader district. Matthew Kielty for NPR hide caption

A child with nodding syndrome waits for treatment at an outreach site in Uganda's Pader district.

Scientists may have solved the mystery of nodding syndrome, a rare form of epilepsy that has disabled thousands of children in East Africa.

The syndrome seems to be caused by the immune system's response to a parasitic worm, an international team reports in the journal Science Translational Medicine. And they think it's the same worm responsible for river blindness, an eye infection that's also found in East Africa.

The finding means that current efforts to eliminate river blindness should also reduce nodding syndrome, says Avi Nath, an author of the study and chief of the section of infections of the nervous system at the National Institute of Neurological Disorders and Stroke.

The adult form of the O. volvulus worm, which causes river blindness and may also be responsible for nodding syndrome. Courtesy of Dr. Thomas B. Nutman/NIAID/NIH hide caption

The adult form of the O. volvulus worm, which causes river blindness and may also be responsible for nodding syndrome.

"We can prevent new infections even if we can't treat the ones who already have nodding syndrome," Nath says. Drugs can kill the parasite in its early stages.

Nodding syndrome usually strikes children between 5 and 16 who live in rural areas of northern Uganda and South Sudan. Their bodies and brains stop growing. And they experience frequent seizures.

"These are kids, young kids, you would expect that they should be running around playing," says Nath, who visited Uganda several years ago. "Instead, if you go to these villages they are just sitting there in groups," so villagers can keep an eye on them.

The epileptic seizures weaken muscles in the head and neck. "So their heads tend to fall forward," Nath says. "And because that happens repeatedly as part of the seizure, it is termed nodding syndrome."

Researchers have struggled to find a cause for the syndrome since it was first documented in Tanzania in the 1960s. "We thought it might have to do with toxins, chemicals in the environment or nutritional deficiency," Nath says.

But the only clue that seemed to hold up was that affected children lived in areas where river blindness was common. This clue was puzzling, though, because even though nodding syndrome is a brain disease, the parasite that causes river blindness doesn't seem to infect the brain.

After returning from Uganda, Nath decided to search for an explanation.

"He pulled all of the lab together as a team and asked us to each investigate different components" of the syndrome, says Tory Johnson, an assistant professor of neurology at Johns Hopkins who was working for Nath at the time. She is also an author of the new study.

Johnson's assignment was to see whether the body's own immune system might play a role. So she began screening blood samples from people with nodding syndrome.

Other scientists had also looked for an immune response. But Johnson's search was much more extensive. "We looked at everything that was available," she says.

And eventually, she found something.

Nath remembers being in a meeting one day when Johnson appeared suddenly. "I saw her waving at me and I'm like, 'Okay, what happened?'" he says.

Johnson had discovered that in people with nodding syndrome, the immune system was targeting a protein found in certain muscle cells. It looked as if the body was attacking itself.

The question was whether the immune system's attack also included the brain. So Johnson started looking to see whether the targeted protein was in brain cells.

"And lo and behold she found that yes, it was not only present in the brain, there were actually large amounts of it present in neurons," Nath says. "So the story really came together very nicely."

The full story, the team's hypothesis, goes like this:

When a person is infected with the river blindness parasite, the immune system begins sending antibodies to attack the invader. These antibodies identify their enemy by looking for a specific protein in the parasite's cells.

Unfortunately, the target protein in the parasite looks a lot like a protein found in certain brain cells. So these brain cells become unintended casualties of the body's efforts to protect itself.

The discovery shows why it's important to treat children soon after they are infected with the parasite, Nath says. That might prevent an immune response that attacks the brain. And it would mean that the parasite can't be spread from person to person by black flies.

Because nodding syndrome appears to be the result of an immune response, Nath says, it may be possible to limit brain damage in some children by using drugs that tone down the immune system response.

The finding also raises the possibility that parasites, or other infections, are causing epilepsy in the U.S. and other countries, Nath says.

"We know there are a large number of immune-mediated epilepsies," Nath says. "But the underlying cause is not clear."

And there are plenty of parasitic infections in the U.S. Pinworms, for example, infect millions of children each year.

It's possible that some of these infections are leading to epilepsy, Johnson says. "We don't know because we haven't looked yet."

Read the rest here:
Scientists May Have Solved The Mystery Of Nodding Syndrome - NPR

CRISPR is a life-changing genetic modification technology that could potentially cure cancer and eradicate genetic conditions before a child is born. But there is a dark side to the potential of this technology.

The patent dispute over CRISPR technology has been settled.

AN INFLUENTIAL US science advisory committee this week said genetic modification of human embryos should be allowed in the future to eliminate diseases, sparking new debate on a controversial topic.

The report by the National Academy of Sciences (NAS) caused concern among some researchers who fear that genetic tools could be used to boost certain peoples intelligence or create people with particular physical traits.

Clinical trials for genome editing of the human germ line adding, removing or replacing DNA base pairs in gametes or early embryos could be permitted in the future, said the report, released Wednesday (AEST).

But only, it added, for serious conditions under stringent oversight.

The emergence of inexpensive and accurate gene-editing technology, known as CRISPR/Cas9, has fuelled an explosion of new research opportunities and potential clinical applications, both heritable and non-heritable, to address a wide range of human health issues, the report said.

The committee of international experts was convened to examine scientific, ethical and governance issues surrounding human genome editing.

The experts noted that clinical trials on gene editing for certain non-hereditary traits are already under way.

These therapies affect only the patient, not any offspring, and should continue for treatment and prevention of disease and disability, using the existing ethical norms and regulatory framework for development of gene therapy, it said.

There is plenty of concern about the designer human floodgates opening.Source:YouTube

The warning come as a major patent battle over the technology was settled in the US in recent days.

What many described as the biotechnology trial of the century, the Broad Institute won the patent to the popular gene-editing process known as CRISPR/Cas-9.

The legal battle over who really invented the technology pitted Feng Zhang of the Broad Institute a research facility affiliated with Harvard University and the Massachusetts Institute of Technology against French microbiologist Emmanuelle Charpentier of the Max Planck Institute in Berlin and biochemist Jennifer Doudna of the University of California, Berkeley.

Both sides claimed to have developed CRISPR-Cas9, which allows scientists to edit stretches of the genome by removing, adding or changing pieces of the DNA sequence.

Jennifer Doudna of UC Berkeley ultimately lost out in the dispute.Source:Getty Images

Scientists say the technology has the potential to cure diseases but also raises ethical questions, particularly when it comes to the prospect of forever altering the human race.

Charpentier and Doudna have won multiple prizes in the past four years and were widely considered to have discovered this gene-editing technique. Their work was first published in the journal Science in June 2012.

This important decision affirms the inventiveness of the Broads work in translating the biology of the natural world into fundamental building blocks to create unprecedented medicines, said a statement by Katrine Bosley, president and chief executive officer of Editas Medicine, which has an exclusive licence on the Broad Institutes patent for human-therapy applications.

The Atlantic magazine described Editas Medicine as the biggest winner.

Assuming the patent decision does not change, Editas will be the major player in human CRISPR therapies in the foreseeable future, it said.

Excerpt from:
The biotechnology trial of the century over CRISPR patent settled in US court - NEWS.com.au

Cavitation Technologies, Inc. (CTi) (OTCQB: CVAT) (Berlin: WTC) and CBDual Biotechnology Corp announced today that the two companies have reached a comprehensive cross-licensing agreement. This agreement covers intellectual property involving application of technology and process patents to produce high quality pharmaceutical grade cannabis materials. The patented technology facilitates the production of cannabinoid formulations that may include Cannabidiol (CBD) and Tetrahydrocannabinol (THC) that can be easily mixed into fluids or medications providing increased stability of products and a much quicker enhanced absorption rate of medications.

Dr. Greg Rubin, CEO of CBDual Biotechnology Corp. commented, "The cannabis derived products market is growing rapidly in North America. Market Research Future reports indicate that U.S., Canada, and Mexico are dominant markets for cannabis products and these markets are expected to grow at 33% per annum from 2016 to 2021. Growing awareness about cannabis medicinal properties is also reflected in growing demand for new CBD based products. The development of consumer and medical products require the development of the best quality and utilization of the most innovative technologies in order to achieve ultimate results. This is only possible if we use the most advanced technological processes and our agreement with CTi enables us to manufacture the best quality CBD based oral care products by utilizing their advanced patented technology."

Global Technology Manager of CTi, Roman Gordon, stated that, "Intellectual property covered by this agreement between our companies enhances the development of cannabis based products and helps us expand into new consumer and medical markets. Cannabis based medicine is now emerging and being revisited as a potential source of treatments for conditions not addressed properly by synthetic substances," concluded Mr. Gordon

CTi's cross-licensing arrangement with CBDual Biotechnology Corp will oversee the infusion of cannabinoids in CBD based oral healthcare product line that includes mouthwash, toothpaste with cannabidiol and other unique formulations. Management also sees the potential to attract a number of potential licensees and distributors across multiple markets, including the therapeutic foods, CBD water, dietary supplements and pharmaceutical industries.

About CTi

Founded in 2007, the company designs and manufactures state-of-the-art, flow-through, devices and systems as well as develops processing technologies for use in edible oil refining, renewable fuel production, expeditious petroleum upgrading, algae oil extraction, alcoholic beverage enhancement and water treatment. As an add-on to its existing neutralization systems, the company's patented Nano Reactor allows refiners to significantly reduce both processing costs and environmental impact, while also increasing yield.

http://www.ctinanotech.com/

About CBDual Biotechnology Corp.

CBDual Biotechnology is a privately held, US based Biotechnology company with a proprietary technology for enhanced oral delivery of bioactive cannabinoids. This technology promotes good gums health and overall dental health due to higher effectiveness of the delivery methodology. Company was founded in 2016 and is headquarted in California with its R&D capability in Israel and Ukraine.

CBDual Biotechnology is a pharmaceutical research and development company, focused on the commercialization of cannabinoids (CBD) based oral hygiene products and for the treatment of gum disease, bad breath, pain and other disorders associated with oral health, including CBD mouthwash, CBD toothpaste and other unique pharmaceutical products. Company conducts medical research and clinical trials in their new clinical research center in California. Company's Medical Advisory Board has experienced, Board certified doctors and specialists that oversee and design clinical research and develop new products.

Welcome to CBDual

Forward Looking Statement

This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. In some cases forward-looking statements can be identified by terminology such as "may," "should," "potential," "continue," "expects," "anticipates," "intends," "plans," "believes," "estimates," and similar expressions, and include statements regarding the anticipated installation and the timing of the installation, our intent to continue to focus on research and development, marketing and sales of our unique technology, our belief that our company is positioned for accelerated growth and the expected efforts to be made to enhance our shareholder's value. These forward-looking statements are based largely on the Company's expectations and are subject to a number of risks and uncertainties, certain of which are beyond the Company's control. Actual results could differ materially from these forward looking statements as a result of a variety of factors including, among others, the state of the economy, the competitive environment and our ability to perform the installation as anticipated and other factors described in our most recent Form 10-K and our other filings with the SEC, including subsequent periodic reports on Forms 10-Q and 8-K. In light of these risks and uncertainties there can be no assurances that the forward looking statements contained in this press release will in fact transpire or prove to be accurate. The information in this release is provided only as of the date of this release, and we undertake no obligation to update any forward-looking statements contained in this release on account of new information, future events, or otherwise, except as required by law.

Cavitation Technologies, Inc.

Contact:

Investor Relations Jessica Steidinger Jessica@ctinanotech.com Phone (818) 718-0905

DISCLOSURE: The views and opinions expressed in this article are those of the authors, and do not represent the views of equities.com. Readers should not consider statements made by the author as formal recommendations and should consult their financial advisor before making any investment decisions. To read our full disclosure, please go to: http://www.equities.com/disclaimer

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Cavitation Technologies, Inc. (CVAT) Announces Cross Licensing ... - Equities.com

Potential therapies for chikungunya arthritis Nature.com Targeting T cells is emerging as a promising strategy for the treatment of chikungunya arthritis. Two independent studies published in Science Translational Medicine demonstrated amelioration of disease when targeting pathogenic CD4+ T cells in mice ...

The rest is here:
Potential therapies for chikungunya arthritis - Nature.com

Nature.com

New player in RA pathogenesis brought to light Nature.com A novel subset of T cells is responsible for driving autoantibody production by B cells in the synovium of patients with rheumatoid arthritis (RA), according to new research published in Nature. These cells, dubbed T 'peripheral helper' cells, are ...

Read the original here:
New player in RA pathogenesis brought to light - Nature.com

The horses of the apocalypse have been galloping in for some time now, and far be it from us to claim that a singer-songwriter from Edmonton has any chance of keeping them at bay. But to listen to Calvin Loves new single Warm Blindness & A Cool Breeze is to accept that maybe everything isnt totally fucked after all. Love has made a name for himself with a series of lush, buoyant pop compositions that temper their sweetness with a bit of bite, and his latest is no different. It does happen to come at a time when we need it most, though, hitting us with a hopeful swell of guitars and a bass line that makes our booties shake for thank god some reason other than fear.

Warm Blindness & A Cool Breeze was written by accident and impulse, the songwriter tells Consequence of Sound. [Its] a metaphor for being lost in a cognitive dissonance while under the pressure of societies imminent apocalypse. Thats not a difficult sentiment to relate to these days, but Love maintains a positive perspective until the bitter end. Just as long as youre here with me/ Everything will be alright, he sings in the coda, and theres nothing really bitter about that at all, is there?

Warm Blindess & A Cool Breeze is off Loves upcomingEcdysis EP, due out April 7th via Modern Sky. Find the info below.

Ecdysis EP Artwork:

Ecdysis EP Tracklist: 01. Warm Blindness & A Cool Breeze 02. When Your Not Looking 03. Sugar Hives 04. Grey Eyes 05. Goodbye Morning

You can catch Love on tour at the following dates:

Calvin Love 2017 Tour Dates: 02/25 Toronto, ON@ Baby G 03/02 Hamilton, ON @ Biltmore House 03/08 Columbus, OH @Space Bar 03/13 Memphis, TN @ The High Tone 03/14 Dallas, TX @ The Crown & Harp 03/15 Austin, TX @ Barracuda 03/19 Austin, TX @ Beerland Panache Hangover Fest 03/23 Chattanooga, TN @ The Open Chord 03/27 Philadelphia, PA @ Johnny Brendas 03/28 Baltimore, MD @ The Metro Gallery 03/30 New York, NY @ Berlin 03/31 New York, NY @ Berlin 04/01 New York, NY @ Berlin 04/03 Montreal, QC @ TBA 04/28 Beijing, CN @ Sound of The City Festival 05/04 Shanghai, CN @ Strawberry Music Festival

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Calvin Love staves off society's imminent collapse with Warm Blindness & A Cool Breeze listen - Consequence of Sound (blog)