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OrphAI Therapeutics Announces Appointment of Jay Fine to Board of Directors
VANCOUVER, British Columbia, Jan. 24, 2024 (GLOBE NEWSWIRE) -- In a release issued under the same headline earlier today by Sirona Biochem Corp. (TSX-V: SBM) (FSE: ZSB) (OTC: SRBCF), please note that in the 8th paragraph of the letter, the company plans to launch its first product early in the 1st quarter of 2025, not the 1st quarter of 2024 as previously stated. The corrected release follows:
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CORRECTION -- Sirona Biochem Corporate Update January 2024
Regeneron Science Talent Search Showcases Exceptional Young Leaders with Innovative Ideas in Science, Technology, Engineering and Math (STEM) Regeneron Science Talent Search Showcases Exceptional Young Leaders with Innovative Ideas in Science, Technology, Engineering and Math (STEM)
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Top 40 High School Scientists in Prestigious Regeneron Science Talent Search to Compete for $1.8 Million in Awards
SOUTH SAN FRANCISCO, Calif., Jan. 24, 2024 (GLOBE NEWSWIRE) -- 23andMe Holding Co. (Nasdaq: ME) (23andMe), a leading human genetics and biopharmaceutical company with a mission to help people access, understand, and benefit from the human genome, announced today that it will report financial results for the fiscal year 2024 (FY2024) third quarter after the market closes on Wednesday, February 7, 2024. The Company will webcast a conference call at 4:30 p.m. Eastern Time on that date to discuss the quarter’s financial results and report on business progress.
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23andMe to Report FY2024 Third Quarter Financial Results
FARMINGTON HILLS, Mich., Jan. 24, 2024 (GLOBE NEWSWIRE) -- Ocuphire Pharma, Inc. (Nasdaq: OCUP), a clinical-stage ophthalmic biopharmaceutical company focused on developing and commercializing small-molecule therapies for the treatment of retinal and refractive eye disorders, today announced that the independent members of its Board of Directors approved equity awards under Ocuphire’s 2021 Inducement Plan, as a material inducement to two new employees in connection with their employment with the Company effective on January 18, 2024. The equity awards were approved in accordance with Nasdaq Listing Rule 5635(c)(4), which also requires a public announcement of equity awards that are not made under a stockholder approved equity plan.
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Ocuphire Pharma Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Daix (France), Long Island City (New York, United States), January 24, 2024 – Inventiva (Euronext Paris and Nasdaq: IVA) (the “Company”), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of patients with non-alcoholic steatohepatitis (“NASH”) and other diseases with significant unmet medical needs, today announced the half-year report of its liquidity contract with Kepler Cheuvreux.Under the liquidity contract granted to Kepler Cheuvreux by Inventiva, the following resources were available in the liquidity account as of December 31, 2023:
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Half-Year Review of Inventiva’s Liquidity Contract with Kepler Cheuvreux
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Revive Therapeutics Ltd. Announces Offering of Up to $3 Million
MOUNTAIN VIEW, Calif., Jan. 24, 2024 (GLOBE NEWSWIRE) -- AbSolutions Med, Inc., a privately held medical device company, announced today that the Food and Drug Administration (FDA) has granted Breakthrough Device Designation for its REBUILD Bioabsorbable (“REBUILD”) abdominal wall closure device. REBUILD met the criteria set by the FDA for Breakthrough Devices, potentially providing a novel treatment of an often irreversibly debilitating condition: incisional hernia. Less than 7% of Breakthrough Devices are in the field of general surgery, making REBUILD a standout product in a sector of medicine struggling to make profound advances.
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AbSolutions Med, Inc. Receives FDA Breakthrough Device Designation for its REBUILD™ Bioabsorbable Abdominal Wall Closure Device
PRESS RELEASE
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BioSenic presents new Phase 3 data on JTA-004 to treat severe osteoarthritis pain at the 2024 OARSI World Congress
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Nicox Provides Fourth Quarter 2023 Financial and Business Highlights
TURKU, Finland and BOSTON, Jan. 25, 2024 (GLOBE NEWSWIRE) -- Faron Pharmaceuticals Ltd. (AIM: FARN, First North: FARON), a clinical-stage biopharmaceutical company pursuing a CLEVER approach to reprogramming myeloid cells to activate anti-tumor immunity in hematological and solid tumor microenvironments, today provided details from its further analysis of data from the completed Phase 1 part of the ongoing BEXMAB trial.
USES AND APPLICATIONS OF BIOTECHNOLOGY
Biotechnological innovations are already part of our daily lives and we find them in pharmacies and supermarkets, among many other places. In addition, they were of key importance during the fight against the COVID-19 pandemic as they helped decipher the genome of the virus and in understanding how our body's defence mechanism works against infectious agents.
Biotechnology will therefore play a crucial role in the society of the future in preventing and containing potential pathogens. But this is just one of its many applications... Below, we review some of the most relevant in different fields:
The development of insulin, the growth hormone, molecular identity and diagnostics, gene therapies and vaccines such as hepatitis B are some of the milestones of biotechnology and its alliance with genetic engineering. In addition, it is also used in the diagnosis of diseases due to its ability to perform very complicated tests in a shorter time and at lower cost.
The revolution of the new smart materials hand-in-hand with biotechnology has only just begun, with the main advantage that it can make easily degradable products. Such products help the environment because they generate less waste at the time of destruction, as is the case with biodegradable plastics.
In addition to the genetically modified foods mentioned above, thanks to biotechnology products such as WEMA have been created, a type of crop resistant to droughts and certain insects that may prove essential in fighting hunger in Africa.
Through bioremediation processes, very useful for ecological recovery, the catabolic properties of microorganisms, fungi, plants and enzymes are used to restore contaminated ecosystems.
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What is Biotechnology? Types and Applications - Iberdrola
Where Does Immunitybio Inc (IBRX) Stock Fall in the Biotechnology Field After It Is Lower By -9.32% This Week? InvestorsObserver
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Where Does Immunitybio Inc (IBRX) Stock Fall in the Biotechnology Field After It Is Lower By -9.32% This Week? - InvestorsObserver
Can Sana Biotechnology Inc (SANA) Stock Rise to the Top of Healthcare Sector Monday? InvestorsObserver
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Can Sana Biotechnology Inc (SANA) Stock Rise to the Top of Healthcare Sector Monday? - InvestorsObserver
Should You Buy Sana Biotechnology Inc (SANA) Stock After it Has Fallen 15.41% in a Week? InvestorsObserver
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Should You Buy Sana Biotechnology Inc (SANA) Stock After it Has Fallen 15.41% in a Week? - InvestorsObserver
Where Does Tscan Therapeutics Inc (TCRX) Stock Fall in the Biotechnology Field After It Is Lower By -9.81% This Week? InvestorsObserver
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Where Does Tscan Therapeutics Inc (TCRX) Stock Fall in the Biotechnology Field After It Is Lower By -9.81% This Week? - InvestorsObserver
Lifestyle tips for youth's bone health: Avoid these habits to prevent arthritis Hindustan Times
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Lifestyle tips for youth's bone health: Avoid these habits to prevent arthritis - Hindustan Times
Our immune system is made up of both individual cells and proteins as well as entire organs and organ systems. The organs of the immune system include skin and mucous membranes, and the organs of the lymphatic system too.
Your skin and mucous membranes are the first line of defense against germs entering from outside the body. They act as a physical barrier with support from the following:
In addition, the reflexes that cause us to cough and sneeze help to free our airways of germs.
The parts of the immune system
The lymphatic system is composed of:
Primary lymphoid organs: These organs include the bone marrow and the thymus. They create special immune system cells called lymphocytes.
Secondary lymphoid organs: These organs include the lymph nodes, the spleen, the tonsils and certain tissue in various mucous membrane layers in the body (for instance in the bowel). It is in these organs where the cells of the immune system do their actual job of fighting off germs and foreign substances.
Bone marrow is a sponge-like tissue found inside the bones. That is where most immune system cells are produced and then also multiply. These cells move to other organs and tissues through the blood. At birth, many bones contain red bone marrow, which actively creates immune system cells. Over the course of our life, more and more red bone marrow turns into fatty tissue. In adulthood, only a few of our bones still contain red bone marrow, including the ribs, breastbone and the pelvis.
The thymus is located behind the breastbone above the heart. This gland-like organ reaches full maturity only in children, and is then slowly transformed to fatty tissue. Special types of immune system cells called thymus cell lymphocytes (T cells) mature in the thymus. Among other tasks, these cells coordinate the processes of the innate and adaptive immune systems. T cells move through the body and constantly monitor the surfaces of all cells for changes.
Lymph nodes are small bean-shaped tissues found along the lymphatic vessels. The lymph nodes act as filters. Various immune system cells trap germs in the lymph nodes and activate the creation of special antibodies in the blood. Swollen or painful lymph nodes are a sign that the immune system is active, for example to fight an infection.
The spleen is located in the left upper abdomen, beneath the diaphragm, and is responsible for different kinds of jobs:
It stores various immune system cells. When needed, they move through the blood to other organs. Scavenger cells (phagocytes) in the spleen act as a filter for germs that get into the bloodstream.
It breaks down red blood cells (erythrocytes).
It stores and breaks down platelets (thrombocytes), which are responsible for the clotting of blood, among other things.
There is always a lot of blood flowing through the spleen tissue. At the same time this tissue is very soft. In the event of severe injury, for example in an accident, the spleen may rupture easily. Surgery is then usually necessary because otherwise there is a danger of bleeding to death. If the spleen needs to be removed completely, other immune system organs can carry out its roles.
The tonsils are also part of the immune system. Because of their location at the throat and palate, they can stop germs entering the body through the mouth or the nose. The tonsils also contain a lot of white blood cells, which are responsible for killing germs. There are different types of tonsils: palatine tonsils, adenoids and the lingual tonsil. All of these tonsillar structures together are sometimes called Waldeyer's ring since they form a ring around the opening to the throat from the mouth and nose.
There is also lymphatic tissue on the side of the throat, which can perform the functions of the palatine tonsils if they are removed.
The bowel plays a central role in defending the body against germs: More than half of all the body's cells that produce antibodies are found in the bowel wall, especially in the last part of the small bowel and in the appendix. These cells detect foreign substances, and then mark and destroy them. They also save information about the substances in order to be able to react more quickly the next time. The large bowel also contains harmless bacteria called gastrointestinal or gut flora. Healthy gut flora make it difficult for germs to spread and enter the body.
Mucous membranes support the immune system in other parts of the body, too, such as the respiratory and urinary tracts, and the lining of the vagina. The immune system cells are directly beneath the mucous membranes, where they prevent bacteria and viruses from attaching.
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What are the organs of the immune system? - InformedHealth.org - NCBI ...
Eggs from men, sperm from women: Stem cell therapy may just turn reproduction upside down! The Economic Times
Arthritis and other rheumatic diseases are common conditions that cause pain, swelling, and limited movement. They affect joints and connective tissues around the body. Millions of people in the U.S. have some form of arthritis.
Arthritis means redness and swelling (inflammation) of a joint. A joint is where 2 or more bones meet. There are more than 100 different arthritis diseases. Rheumatic diseases include any condition that causes pain, stiffness, and swelling in joints, muscles, tendons, ligaments, or bones. Arthritis is usually ongoing (chronic).
Arthritis and other rheumatic diseases are more common in women than men. They are also often linked with old age. But they affect people of all ages.
The 2 most common forms of arthritis are:
Osteoarthritis. This is the most common type of arthritis. It is a chronic disease of the joints, especially the weight-bearing joints of the knee, hip, and spine. It destroys the coating on the ends of bones (cartilage) and narrows the joint space. It can also cause bone overgrowth, bone spurs, and reduced function. It occurs in most people as they age. It may also occur in young people because of an injury or overuse.
Rheumatoid arthritis. This is an inflammatory disease of the joint linings. The inflammation may affect all of the joints. It can also affect organs such as the heart or lungs.
Other forms of arthritis or related disorders include:
Gout. This condition causes uric acid crystals to build up in small joints, such as the big toe. It causes pain and inflammation.
Lupus. This is a chronic autoimmune disorder. It causes periods of inflammation and damage in joints, tendons, and organs.
Scleroderma. This autoimmune disease causes thickening and hardening of the skin and other connective tissue in the body.
Ankylosing spondylitis. This disease causes the bones of the spine to grow together. It can also cause inflammation in other parts of the body. It can affect the shoulders, hips, ribs, and the small joints of the hands and feet.
Juvenile idiopathic arthritis (JIA) or juvenile rheumatoid arthritis (JRA). This is a form of arthritis in children that causes inflammation and joint stiffness. Children often outgrow JRA. But it can affect bone development in a growing child.
The cause depends on the type of arthritis. Osteoarthritis is caused by the wear and tear of the joint over time or because of overuse. Rheumatoid arthritis, lupus, and scleroderma are caused by the bodys immune system attacking the bodys own tissues. Gout is caused by the buildup of crystals in the joints. Some forms of arthritis can be linked to genes. People with genetic marker HLA-B27 have a higher risk of ankylosing spondylitis. For some other forms of arthritis, the cause is not known.
Some risk factors for arthritis that cant be avoided or changed include:
Age. The older you are, the more likely you are to have arthritis.
Gender. Women are more likely to have arthritis than men.
Heredity. Some types of arthritis are linked to certain genes.
Risk factors that may be avoided or changed include:
Weight. Being overweight or obese can damage your knee joints. This can make them more likely to develop osteoarthritis.
Injury. A joint that has been damaged by an injury is more likely to develop arthritis at some point.
Infection. Reactive arthritis can affect joints after an infection.
Your job. Work that involves repeated bending or squatting can lead to knee arthritis.
Each persons symptoms may vary. The most common symptoms include:
Pain in 1 or more joints that doesnt go away, or comes back
Warmth and redness in 1 or more joints
Swelling in 1 or more joints
Stiffness in 1 or more joints
Trouble moving 1 or more joints in a normal way
These symptoms can look like other health conditions. Always see your healthcare provider for a diagnosis.
Your healthcare provider will take your medical history and give you a physical exam. Tests may also be done. These include blood tests such as:
Antinuclear antibody (ANA) test. This checks antibody levels in the blood.
Complete blood count (CBC). This checks if your white blood cell, red blood cell, and platelet levels are normal.
Creatinine. This test checks for kidney disease.
Sedimentation rate. This test can find inflammation.
Hematocrit. This test measures the number of red blood cells.
RF (rheumatoid factor) and CCP (cyclic citrullinated peptide) antibody tests. These can help diagnose rheumatoid arthritis. They can also assess how severe the disease is.
White blood cell count. This checks the level of white blood cells in your blood.
Uric acid. This helps diagnose gout.
Other tests may be done, such as:
Joint aspiration (arthrocentesis). A small sample of synovial fluid is taken from a joint. It's tested to see if crystals, bacteria, or viruses are present.
X-rays or other imaging tests. These can tell how damaged a joint is.
Urine test. This checks for protein and different kinds of blood cells.
HLA tissue typing. This looks for genetic markers of ankylosing spondylitis.
Skin biopsy. Tiny tissue samples are removed and checked under a microscope. This test helps to diagnose a type of arthritis that involves the skin, such as lupus or psoriatic arthritis.
Muscle biopsy. Tiny tissue samples are removed and checked under a microscope. This test helps to diagnose conditions that affect muscles.
Treatment will depend on your symptoms, your age, and your general health. It will also depend on how what type of arthritis you have, and how severe the condition is. A treatment plan is tailored to each person with his or her health care provider.
There is no cure for arthritis. The goal of treatment is often to limit pain and inflammation, and help ensure joint function. Treatment plans often use both short-term and long-term methods.
Short-term treatments include:
Medications. Short-term relief for pain and inflammation may include pain relievers such as acetaminophen, aspirin, ibuprofen, or other nonsteroidal anti-inflammatory medications.
Heat and cold. Pain may be eased by using moist heat (warm bath or shower) or dry heat (heating pad) on the joint. Pain and swelling may be eased with cold (ice pack wrapped in a towel) on the joint.
Joint immobilization. The use of a splint or brace can help a joint rest and protect it from further injury.
Massage. The light massage of painful muscles may increase blood flow and bring warmth to the muscle.
Transcutaneous electrical nerve stimulation (TENS). Pain may be reduced with the use of a TENS device. The device sends mild, electrical pulses to nerve endings in the painful area. This blocks pain signals to the brain and changes pain perception.
Acupuncture. This is the use of thin needles that are inserted at specific points in the body. It may stimulate the release of natural, pain-relieving chemicals made by the nervous system. The procedure is done by a licensed health care provider.
Long-term treatments include:
Disease-modifying antirheumatic drugs (DMARDs). These prescription medications may slow down the disease and treat any immune system problems linked to the disease. Examples of these medications include methotrexate, hydroxychloroquine, sulfasalazine, and chlorambucil.
Corticosteroids. Corticosteroids reduce inflammation and swelling. These medications, such as prednisone, can be taken orally or as an injection.
Hyaluronic acid therapy. This is a joint fluid that appears to break down in people with osteoarthritis. It can be injected into a joint, such as the knee, to help relieve symptoms.
Surgery. There are many types of surgery, depending on which joints are affected. Surgery options may include arthroscopy, fusion, or joint replacement. Full recovery after surgery takes up to 6 months. A rehabilitation program after surgery is an important part of the treatment.
Arthritis treatment can include a team of health care providers, such as:
Orthopedist/orthopedic surgeon
Rheumatologist
Physiatrist
Primary care doctor (family medicine or internal medicine)
Rehabilitation nurse
Dietitian
Physical therapist
Occupational therapist
Social worker
Psychologist or psychiatrist
Recreational therapist
Vocational therapist
Because arthritis causes joints to worsen over time, it can cause disability. It can cause pain and movement problems. You may be less able to carry out normal daily activities and tasks.
There is no cure for arthritis. But its important to help keep joints working by reducing pain and inflammation. Work on a treatment plan with your healthcare provider that includes medicine and therapy. Work on lifestyle changes that can improve your quality of life. Lifestyle changes include:
Weight loss. Extra weight puts more stress on weight-bearing joints, such as the hips and knees.
Exercise. Some exercises may help reduce joint pain and stiffness. These include swimming, walking, low-impact aerobic exercise, and range-of-motion exercises. Stretching exercises may also help keep the joints flexible.
Activity and rest. To reduce stress on your joints, switch between activity and rest. This can help protect your joints and lessen your symptoms.
Using assistive devices. Canes, crutches, and walkers can help keep stress off certain joints and improve balance.
Using adaptive equipment. Reachers and grabbers let you extend your reach and reduce straining. Dressing aids help you get dressed more easily.
Managing use of medicines. Long-term use of some anti-inflammatory medicines can lead to stomach bleeding. Work with your healthcare provider to create a plan to reduce this risk.
Call your provider if your symptoms get worse or you have new symptoms.
Arthritis and other rheumatic diseases cause pain, swelling, and limited movement in joints and connective tissues in the body.
Arthritis and other rheumatic diseases can affect people of all ages. They are more common in women than men.
Symptoms may include pain, stiffness, swelling, warmth, or redness in 1 or more joints.
There is no cure for arthritis. The treatment goal is to limit pain and inflammation and preserve joint function.
Treatment options include medicines, weight reduction, exercise, and surgery.
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Arthritis | Johns Hopkins Medicine