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Endothelial Progenitor Stem Cells in Lupus Cardiovascular Disease – Video

December 16th, 2011 5:16 pm

Systemic lupus is associated with significant increases in premature heart attacks. Dr

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Endothelial Progenitor Stem Cells in Lupus Cardiovascular Disease - Video

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5 Things you should know about stem cell research – Video

December 16th, 2011 5:15 pm

Michigan voters soon will decide whether to change a Michigan law that currently restricts research using embryonic stem cells.

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Stem Cell Based Lab Grown Meat coming soon – Video

December 16th, 2011 5:15 pm

Stem Cell based lab grown meat... http://www.sott.net FAIRUSE: This site may contain copyrighted material the use of which has not always been specifically authorized by the copyright owner

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Stem Cell Friends Meet in Panama – Video

December 16th, 2011 3:09 am

Holly Huber and Judi Lecoq ... we got together for dinner while both in Panama City, Panama for continuing stem cell treatment for Multiple Sclerosis.

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Christian Wilde on Stem Cell at Health Freedom Expo.MP4 – Video

December 16th, 2011 3:09 am

Christian Wilde on Stem Cell technology from own bone marrow at Health Freedom Expo. This technology is ALREADY saving lives of patients all over the world with different diseases affecting most human organs, including cancer, heart attacks, diabetes, MS, and any organ failures

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News Update: Judge Rules Against Obama’s Stem Cell Policy – Video

December 16th, 2011 3:08 am

A federal judge's Monday ruling blocked President Obama's 2009 order to expand embryonic stem cell research. Chief Judge Royce Lamberth of DC's Federal District Court says the presidential order violates a ban on using federal money to destroy embryos

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Republican Presidential Candidate Video Question – Video

December 16th, 2011 3:08 am

Should any of you on the stage tonight become President, would you enact into Law The Stem Cell Reseach Enactment Act of 2007, if Yes why? if No why not? Do not confuse this question with the Clonig Issue

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Virginia 18th State to Legislate Cord Blood Education – Video

December 16th, 2011 3:08 am

http://www.stemcellbuzz.net Last week, the Governor of Virginia, Bob McDonnell, signed the states Cord Blood Education Bill (HB85) into law requiring the State Department of Health to publish information on its website about cord blood stem cells and parents options of preserving them. The new law also requires prenatal care physicians to educate expectant parents about their options early enough in pregnancy so that they can make an informed decision about whether to privately bank their childs newborn stem cells or donate them to a public bank. With the passage of the Virginia law, 18 states -- representing two-thirds of the US population -- now benefit from state-endorsed education on cord blood stem cells and the private and public cord blood banking options available to parents.

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2011 Summit: Stem Cells, Reprogramming and Personalized Medicine, Rudolf Jaenisch, MD – Video

December 15th, 2011 6:43 am

Rudolf Jaenisch, MD (MIT) and recently named winner of the National Medal of Science, discussed the key issues facing the field of highly pluripotent stem cells including ES cells and iPS cells. He outlined the main conditions that affect the quality of stem cells including genetics background, culture, isolation and environmental conditions, adding that subtle phenotypes may be disease relevant

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2011 Summit: Government

December 14th, 2011 6:50 pm

Robert Klein, former chair of the California Institute of Regenerative Medicine (CIRM), presented this year's advocacy keynote, addressing the looming black cloud over funding for stem cell research in the US. Klein explained that in a financial downturn, creating long term, big picture investments for donors is absolutely necessary to bring to new treatment modalities to market.

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2011 Summit: Government

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Arthritis Treatment Complications of stem cell procedures – Tip 5 – Video

December 14th, 2011 5:09 pm

Arthritis Treatment Complications of stem cell procedures - Tip 5

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2011 Summit: Keynote Address, CIRM’s Translational Roadmap to Stem Cell Cures, Alan Trounson, PhD – Video

December 14th, 2011 5:06 am

Alan Trounson, PhD and President of the California Institute for Regenerative Medicine, offered a positive and forward looking keynote address. Trounson provided an update on CIRM's translational roadmap to regenerative medicine and outlined their accomplishments with over $300 million in funding for human embryonic stem cell research, adult stem cells, cancer stem cells, reprogrammed stem cells and endogenous stem cells for multiple treatments

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2011 Summit: Keynote Address, CIRM's Translational Roadmap to Stem Cell Cures, Alan Trounson, PhD - Video

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2011 Summit: Harnessing Regenerative Medicine for US Service-members, Major General James K. Gilman – Video

December 14th, 2011 5:06 am

Major General James Gilman, Commanding General of the US Army Medical Research and Material Command, outlined the US army's extensive research efforts in stem cell technologies and their mission to discover, develop and translate regenerative medicine. He spoke about the military's desire to partner with academia and industry to generate effective treatments for volume, bone, muscle and tissue injuries and about spinal cord regeneration as the military's biggest challenge and hope.

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2011 Summit: Harnessing Regenerative Medicine for US Service-members, Major General James K. Gilman - Video

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A New Role for Old Sox – Video

December 13th, 2011 12:19 pm

Understanding the genetic underpinnings of the biology of stem cells is crucial for their use in disease research and treatment. Scientists have identified a variety of genetic factors that maintain self renewal properties in embryonic, fetal, and adult stem cells

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A New Role for Old Sox - Video

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Peripheral Blood Stem Cells From Unrelated Donors – Video

December 13th, 2011 12:19 pm

A new study finds filgrastim-mobilized peripheral blood stem cells convey no survival advantage over bone marrow transplants when the donor is not an HLA-identical sibling of the recipient. In an interview at the annual meeting of the American Society of Hematology, Dr. Claudio Anasetti explains why the findings could cause bone marrow transplants to be reconsidered for some patients with hematological malignancies.

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Peripheral Blood Stem Cells From Unrelated Donors - Video

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Embryonic Stem Cells – Video

December 13th, 2011 12:19 pm

An overview of early development of a zygote to an embryo. Embryonic and somatic stem cells.

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Adult Stem Cell Therapy: Side Effects of Umbilical Cord Derived Stem Cells – Video

December 12th, 2011 5:05 pm

Dr. Neil Riordan presents data on human umbilical cord-derived stem cell treatments. Dr.

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Adult Stem Cell Therapy: Side Effects of Umbilical Cord Derived Stem Cells - Video

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BioLife Administrative Manager Talks About BioLife Cell Banking – Video

December 12th, 2011 1:23 pm

Biolife Cell Banking Director of Marketing talks to the Administrative Manager of BioLife about fat and stem cell banking at BioLife Cell Banking Services.

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BioLife Administrative Manager Talks About BioLife Cell Banking - Video

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Mesenchymal Stem Cells Drive New MS Study/Treatment – Video

December 11th, 2011 10:09 pm

A great video featuring promise held by a new study from Case Western Reserve University on Adult Stem Cell treatment for Multiple Sclerosis.

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Mesenchymal Stem Cells Drive New MS Study/Treatment - Video

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Active phase III or II/III cell therapy trials

December 11th, 2011 5:07 pm
Tweet 
I know that the moment I publish anything that purports to be comprehensive there will be errors and omissions.  At the very least it will almost imminently be out-of-date in a fast-moving sector like cell therapy.
Nonetheless, because there is no other reliable repository of this information, I am daring to put this out there and hope you will feel obligated to assist me in ensuring its accuracy rather than critical of the effort.
What follows is what I currently believe to an current and relatively comprehensive list of phase III or II/III cell therapy trials around the world.  I am more confident of the industry list than the academic one.  More confident of its completeness and accuracy for North American and Europe than of Asia (particularly China). 
There is a spreadsheet behind this that includes more data fields like therapeutic category, cell/tissue source, cell type, expansion, indication, expected completion date, clinical trial site locations, etc.  If you want a copy of it, just email me (I'm not hard to find) or comment below.

INDUSTRY PHASE III or II/III (active or expected to be active in 1H 2012)  

       
    Aastrom                         Ixmyelocel-T
    Baxter                            ACT34-CMI
    Bioheart                         Myocell
    Cardio3 Biosciences         C-CURE
    Cardio3 Biosciences         C-CURE
    Cell Medica                     adoptive cellular therapy
    Cook Myosite                  AMDC
    Cytori                            ADRCs
    GamidaCell - Teva           StemEx
    Genzyme                        MACI
    Harvest Technologies       SmartPReP 2 BMAC
    Innovaell                        IES13 (Urocell?)
    Kiaidis Pharma                ATIR
    Miltenyi                         CliniMACS CD34 Selection System
    Medipost                       Cartistem
    MolMed                         TK
    Newlink Genetics            HyperAcute Pancreas
    NovaRx                         Lucanix
    Osiris                           Prochymal
    Osiris                           Prochymal
    Pervasis                        Vasugel
The 21 active or imminently active cell therapy industry-sponsored trials listed above break down as follows:
    • 52% (12) are autologous
    • 33% (7) are allogeneic
    • Two are gene-modified allogeneic
    • One involves autologous and allogeneic cells
    • 24% (5) are for cardiac-related indications
    • 33% (7) are for oncology or related indications
    • Two are for cartilage repair

 
* ACADEMIC PHASE III or II/III
  • Assistance Publique - Hôpitaux de Paris (France)
  • Association of Dutch Burn Centres (Netherlands)
  • Barts and The London NHS Trust (UK)
  • Erasmus Medical Center (Netherlands)
  • European Group for Blood and Marrow Transplantation (Europe)
  • Leiden University Medical Center (Netherlands)
  • Meshalkin Research Institute of Pathology of Circulation (Russia)
  • Meshalkin Research Institute of Pathology of Circulation (Russia)
  • Ministry of Health (Malaysia)
  • Royan Institute (Iran)
  • Rush University Medical Center, University of Sao Paulo, Uppsala University (US, Brazil, Sweden)
  • Third Military Medical University (Chia)
  • University of Minnesota, Masonic Cancer Center (US)
  • University of Minnesota, Masonic Cancer Center (US)
  • University Hospital of North Norway (Norway)
  • University of Utah (US)
* Active trials only - excludes trials which appear inactive, abandoned, and/or are stem cell transplant in oncology.  Primary source is CinicalTrials.gov.
___________________________________
I will try to keep this list updated at least once-per-quarter and indicate the date of the last update at the top of the post.
I eagerly encourage all readers to comment below or email direct with any errors and/or omissions.
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