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Touch on the Medical Team: As Massage is Implemented in Integrative Care, Specialized Competencies Become More Important – Massage Magazine

November 5th, 2020 9:52 am

In recent decades, as the evidence base for massage and the acceptance of massage have grown, professional opportunities available to massage therapists have also broadened.

Now with integrative health care becoming more prevalent, massage is often part of these integrative care teams, with massage therapists working alongside medical, allied health care and other complementary practitioners. Hospital environments and integrative care settings are both areas that benefit from massage training that addresses specific competencies related to them.

These varying work environments mean that massage therapists are working with a wide range of patients, some with complex and serious health conditions and very specific health needs. These may necessitate adaptations to treatment or may involve contraindications.

They may require working around equipment, a deep understanding of specific diseases or knowledge of specific medical treatments. These varied environments also find massage therapists working with health care practitioners from a range of disciplines, which makes an understanding of each others work, abilities, specialties and scope of practice important.

Current massage therapy education varies from one school to another. The competencies provided by standard massage therapy training in the U.S. are more than sufficient for working in more general environments. However, the therapist presented with some of these specialized clinical opportunities may benefit from additional training that provides enhanced competencies to meet their very specific needs.

Some schools offer hospital-based massage therapy programs; however, among them there may be a lack of consistency regarding curriculum and competencies. While there have been ever-increasing trends toward integrative care and interdisciplinary research, training that addresses specific competencies for complementary health care practitioners working in integrative environments is not as common.

Within the medical community there have been efforts to define outcome-based competencies for health care1. Doing the same for massage in hospital or integrative care environments seems prudent.

The Academic Collaborative for Integrative Health (ACIH) established the Hospital-Based Massage Therapy (HBMT) Task Force in 2012. Their goal was to assess current HBMT training and implementation and to develop a set of specific HBMT competencies. The ACIH Competencies for Optimal Practice in Integrated Environments were used as a basis for broad categories of competencies and feedback from representatives of hospitals that included HBMT programs was incorporated.

The HBMT Task Force identified that there was a wide range of practice standards and delivery of massage therapy in hospital settings. While some HBMT programs required specific education of their therapists, many did not and many felt that therapists required further specific training once hired to meet the needs of the particular programs2.

The competencies that representatives of HBMT programs felt were often lacking included some related to clinical practice and others that related to the environment, such as oncology training, proper documentation of assessments and treatment plans, appropriate therapeutic relationships, an understanding of medical terminology and medical devices, infection control, and competencies related to the hospital environment and interdisciplinary collaboration2.

The finalized competencies developed by the HBMT Task Force included some relevant competencies from the ACIH along with new ones that address issues that are specifically relevant to HBMT practice. These include competencies related to:

There are a number of benefits to having a set list of competencies specifically related to working in the hospital environment. They can be of benefit to massage therapists, to hospital-based massage therapy programs, and to other stakeholders.

Distinct competencies related to HBMT can be of benefit to massage therapists by first helping them to ascertain if this type of work will be a good fit for them. Not only will they be able to determine if they have the skills required, but also if they would enjoy working in this environment. Knowing what competencies are involved will also allow therapists to seek out appropriate training to prepare them to succeed in these roles.

HBMT competencies can help with the development of education. Massage schools and continuing education providers will be able to develop training to address these specific competencies.

Regulatory bodies and professional associations could use the competencies as the basis for specialty certification. We have seen this in other areas, for example in performing arts medicine and in oncology massage.

Hospitals could use these competencies to inform the interview process and to evaluate potential massage therapists for their programs. Additionally, hospitals could benefit from these competencies as they could provide standards for those wishing to establish HBMT programs.

Research is another area that could benefit from these competencies. The rigor of research studies carried out within these programs may be enhanced by ensuring that the delivery of massage interventions are carried out by therapists with specific competencies related to the hospital environment.

And finally, the public would benefit from HBMT competencies. First, patient needs could be better met if massage therapists have training that provides them with the relevant competencies. And secondly, we may find that there is increased interest in and appreciation of massage because of these definitive skills and competencies.

There is some overlap between competencies for integrative care settings and those of HBMT, as a number of HBMT programs could be considered to be integrative. However, as integrative care becomes more commonplace, there are opportunities for this type of collaborative and integrative workplace, both outside of the hospital setting and within it in outpatient clinics in which one may not encounter patients with serious or life-threatening illness.

Massage therapists are often working alongside other health care practitioners in collaborative and integrative teams.Regardless of the type of integrative care setting, inter-professional education and integrative health care education are important for anyone working in these environments.

More than 50% of all medical schools in North America now have programs in integrative medicine3. There are a number of programs that have developed in recent years that address inter-professional education, such as the BRIDG (Building Research across Interdisciplinary Gaps) program4. They allow complementary and integrative clinicians to learn alongside biomedical clinicians and researchers. They provide each group with knowledge and understanding of the other so that they might work together more effectively.

The Academic Consortium for Complementary and Alternative Health Care (ACCAHC), an organization whose aim is to advance collaborative and integrative care, has developed Competencies for Optimal Practice in Integrated Environments5. These competencies emphasize inter-professional education, practice and communication, as well as knowledge of roles and responsibilities6.

There are several specific competencies that may enable massage therapists to work effectively and successfully within integrative settings. One of these is knowledge of other modalities and indications for their use. Coupled with this is a basic understanding of other clinicians scope of practice.

Education regarding effective communication across disciplines is also important. Additionally, training around strategies to foster inter- and intra-disciplinary collaboration is beneficial.

The skillful use of electronic patient records (EPR) is another helpful competency. This allows for easy communication with other clinicians regarding patients and patient notes and can enable collaboration.

The benefits of specific competencies for working in integrative settings are many. There are benefits for the massage therapist, for other practitioners, for the clinic or program itself and for the patient.

Knowledge of others disciplines and scopes of practice can promote a team atmosphere. This ability to work as a team is linked to practitioner satisfaction and well-being, as well as decreased stress7. An understanding of other disciplines, scopes of practice and specializations facilitates appropriate referrals, thus benefitting patients, and fosters respect among practitioners.

A collaborative, cohesive clinical team has also been shown to promote innovation and effectiveness8. Patient needs are more effectively addressed when practitioners have an understanding of how different therapies can be combined to complement and build on each other, providing outcomes that are greater than the sum of their individual parts9.

Programs such as BRIDG, which cultivate knowledge of research best practices among clinicians and knowledge of clinical research amongst researchers, can lead to greater practitioner involvement in research studies4. This will enable massage research that is practice-driven, and which can be used to inform practice.

As massage and other complementary health care practices take on a bigger role in our health care system, specialized training and very specific competencies may be necessary to allow therapists to thrive in a range of environments.

Regardless of the professional path we choose to take, giving ourselves the tools we need to have a successful and satisfying career is the first step of that path. We cannot build the career we wish without a solid foundation upon which to build it.

Leisa Bellmore, MSc, ST, wrote this article on behalf of the Massage Therapy Foundation. She has been practicing shiatsu therapy since 2001 and is part of the integrative team at Toronto Western Hospitals Artists Health Centre. She has presented and published around the world. She is a past president of Natural Health Practitioners of Canada and sits on the Massage Therapy Foundation Writing Committee. Bellmore has an MSc in Complementary Medicine Research. Her research interests include neurological conditions, chronic pain and self-management.

1. Grant, K. E., Balletto, J., LMT, B. S., Gowan-Moody, D., Rmt, H., Healey, D., LMP, P. (n.d.). Steps Toward Massage Therapy Guidelines: A First Report to the Profession.

2. Brennan, M. K., Healey, D., Tague, C., & Rosenthal, B. (2019). Hospital based massage therapy specific competencies. Journal of Bodywork and Movement Therapies, 23(2), 291294. doi.org/10.1016/j.jbmt.2019.01.009

3. Eisenberg, D.M., Kaptchuk, T.J., Post, D.E., Hrbek, A.L., OConnor, B.B., Osypiuk, K., Levy, D.B. (2016). Establishing an integrative medicine program within an academic health center: Essential considerations. Academic Medicine, 91(9), 12231230.

4. Bradley, R., Booth-Laforce, C., Hanes, D., Scott, C., Sherman, K.J., Lin, Y.S., & Zwickey, H. (2019). Design of a multidisciplinary training program in complementary and integrative health clinical research: Building research across interdisciplinary gaps. Journal of Alternative and Complementary Medicine, 25(5), 509516.

5. Goldblatt, E., Wiles, M., Schwartz, J., Weeks, J. (2013, September). Competencies for optimal practice in integrated environments: Examining attributes of a consensus interprofessional practice document from the licensed integrative health disciplines. Explore: The Journal of Science and Healing.

6. Goldblatt, E., Weeks, J., & Rosenthal, B. (2010). Competencies for Optimal Practice in Integrated Environments. Academic Consortium for Complementary & Alternative Health Care. (June). Retrieved from

7. Haward, R., Amir, Z., Borrill, C., Dawson, J., Scully, J., West, M., Sainsbury, R. (2003). Breast cancer teams: the impact of constitution, new cancer workload, and methods of operation on their effectiveness. British Journal of Cancer, 89(1), 1522.

8. Proudfoot, J., Jayasinghe, U.W., Holton, C., Grimm, J., Bubner, T., Amoroso, C., Harris, M.F. (2007). Team climate for innovation: What difference does it make in general practice? International Journal for Quality in Health Care. 19(3), 164169.

9. Boon, H.S., Mior, S.A., Barnsley, J., Ashbury, F.D., & Haig, R. (2009). The Difference Between Integration and Collaboration in Patient Care: Results From Key Informant Interviews Working in Multiprofessional Health Care Teams. Journal of Manipulative and Physiological Therapeutics. 32(9), 715722.

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Touch on the Medical Team: As Massage is Implemented in Integrative Care, Specialized Competencies Become More Important - Massage Magazine

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Asia Pacific cannabis market is expected to reach US$ 22,870.6 million by 2027 from US$ 2,318.6 million in 2019 – GlobeNewswire

November 5th, 2020 9:52 am

New York, Nov. 03, 2020 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Asia Pacific Cannabis Market Forecast to 2027 - COVID-19 Impact and Regional Analysis By Product Type ; Application ; Compound, and Country" - https://www.reportlinker.com/p05978820/?utm_source=GNW However, restriction on the use of cannabis in the region is likely to hinder the market growth during the forecast period.

In recent years, the liberation for the use of cannabis in the medical industry has created various growth opportunities in Southeast Asian countries.Growing legal jurisdictions have enabled the progress of research activities in countries, such as South Korea, Australia, and New Zealand.

Also, various international companies have shown interest in effective market strategies.The companies have strategically enhanced their operational activities by partnering with local players.

For instance, a Canadian market player, Canopy Growth, has expanded its production in South Korea and Thailand.Similarly, MYM Nutraceuticals has expanded its business through its subsidiary MYM Australia.

Such expansions by the companies are expected to drive the cannabis market in the region.

Thailand is among the largest producers of cannabis.In late 2018, it became a cannabis production hub for legalized medical cannabis.

In addition, in December 2018, the military of Thailand voted to legalize medical cannabis use and in February 2019, Thailand legalized medical use of cannabis.Similarly, in January 2019, the Philippine House of Representatives approved the legalization of cannabis in the Philippines.

It has also created a Medical Cannabis Compassionate Center to initiate the creation of a legal cannabis industry.In March 2019, South Korea legalized medical use of cannabis.

Moreover, in March 2019, Japan approved the cannabis compound Epidiolex for clinical trials. Thus, such approvals for cannabis-based products are likely to drive market for cannabis in the Asia Pacific region.On the other hand, the COVID-19 outbreak is growing in an unexpected way.For instance, according to an article published in May 2020, saying, "The study mentions how they have identified a minimum of 13 cannabis plants that are high in CBD that can affect the ACE2 pathways that the coronavirus uses to get inside ones body".

Therefore, it is expected to increase the use of medical cannabis to treat symptoms of COVID-19.

Based on product type, the Asia Pacific cannabis market is segmented into flower, concentrates, and others.In 2019, the flower segment held the largest market share of the cannabis market.

However, the concentrates segment is expected to witness the highest CAGR in the next few years.In terms of application, the Asia Pacific cannabis market is segmented into medical and recreational.In 2019, the medical segment held larger share of the market.

However, the recreational segment is anticipated to witness fastest growth during the forecast period.

Based on compound, the Asia Pacific cannabis market is segmented into tetrahydrocannabinol (THC)-dominant, cannabidiol (CBD)-dominant, and balanced THC and CBD.In 2019, the tetrahydrocannabinol (THC)-dominant segment held the largest share of the market.

However, the cannabidiol (CBD)-dominant segment is anticipated to witness fastest growth during the forecast period.

Council of Scientific Researchs Indian Institute of Integrative Medicine, Centre for Narcotics Training, and International Cannabis and Ministry of Food and Drug Safety are among the major primary and secondary sources for the Asia Pacific cannabis market.Read the full report: https://www.reportlinker.com/p05978820/?utm_source=GNW

About ReportlinkerReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

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Recipients of the Sunstar|RDH Award of Distinction 2020 | Registered Dental Hygienist – RDH

November 5th, 2020 9:52 am

Introduction

The Sunstar/RDH Award of Distinction is presented to licensed dental hygienists who go above and beyond typical hygiene practice. They serve as role models and mentors to us all and use their education and talents to make this world a better place. Traditionally, award recipients are honored at RDH Under One Roof, a three-day action-packed event offering quality hygiene education and a chance to mingle with fellow hygienists. Due to the COVID-19 pandemic, this years event was held virtually on October 911.

Although the 2020 recipients of the Sunstar/RDH Award of Distinction were unable to receive their awards in person this year, we still take immense pride in introducing the four recipients of the award to you here. Jennifer Geiselhofer, Jaci Klepadlo, Lisandra Maisonet, and Karen Thomas are the four newest dental hygienists to join this prestigious group of key influencers. Congratulations to the 2020 Sunstar/RDH Award of Distinction recipients! You make us all proud to be dental hygienists!

(Denver, Colorado)

Like most hygienists, Jennifer Geiselhofer began her career in private practice. During her 23 years in a general dentistry practice, she found that her real passion was for dental Missions of Mercy. This passion for the underserved led her to create a portable preventive dental business called Dental at Your Door.

Jennifer Geiselhofer, RDHDental at Your Door is a for-profit business that brings much-needed oral health care to Denvers homeless and underserved population. Jennifer brings preventive dental care to those in homeless shelters, correctional facilities, substance abuse facilities, group homes, womens shelters, runaway youth shelters, human trafficking recovery facilities, and more.

The mission of Dental at Your Door is to provide access to high-quality preventative dental health care. This includes serving patients of all ages with significant health issues, mobility challenges, and financial limitations.

But still, Jennifer worried about those whom she couldnt treatthe people who had to be turned away because they did not have private insurance or did not qualify for state assistance and couldnt afford to self-pay. So she created a 501(c)(3) nonprofit called Deserving Dental, which is funded through grants and donations.

Jennifer has three dental assistants and four hygienists working with her to provide preventive oral health services to those who would not be able to afford it otherwise. They provide prophies, scaling and root planing, digital x-rays, oral cancer screenings, exams, sealants, silver diamine fluoride, and referrals to dental and medical officesall while providing their patients with hope and teaching them the value of a clean mouth and how it can affect their overall health.

One of Jennifers dental assistants nominated her for the Sunstar/RDH Award of Distinction. She stated, After having a dental visit with Jennifer, a lot of patients are so happy with their care that they leave emotional, grateful, and even like to give hugs.

Many of their male patients have shaved their beards after a cleaning because they dont want to hide their teeth anymore!

Referrals to dentists and physicians are important for patients who have completed visits with Jennifer and her team. Jennifer has partnered with several Medicaid-approved providers such as general dentists, oral surgeons, head-and-neck physicians, and ENTs for continuing-care referrals.

One nominator stated, Dental at Your Door was a huge accomplishment considering how many hoops she had to jump through, tears shed, and countless hours spent getting everything in order that she needed to start her dream! Because Jennifer followed that dream of serving the underserved, she has become a recipient of the 2020 Sunstar/RDH Award of Distinction.

Congratulations, Jennifer Geiselhofer!

(Mays Landing, New Jersey)

Invest in yourself and give back to others is Jaci Klepadlos advice to other hygienists. Giving back to others is second nature to Jaci. In addition to working as a clinical hygienist for 13 years, she has served as past president of the New Jersey Dental Hygienists Association (NJDHA) and is currently cochair of Veterans Smile Day Foundation. According to one of Jacis nominators, Finding out Jaci was cochair on the team was no surprise at all. Her hard work and determination are a force to reckon with. She could get through any hurdles thrown her way.

Jaci Klepadlo, BSDH, RDHAs president of the NJDHA, Jaci introduced a bill for dental hygienists to have direct access to providing oral health care, because she strongly believes that public health dental hygienists are willing and fully qualified to reach the underserved where they live.

Jaci became involved with Veterans Smile Day Foundation with her employer, a former navy dentist. After serving in Afghanistan, her employer returned to New Jersey and learned that veterans receive dental benefits only if they have retired from the military or were injured in the line of duty. This information left the vast majority of those who served without dental care, and those who do receive it have to travel great distances to get to a VA clinic that has a dental component on-site.

Jaci and her employer made it their mission to give back to veterans, and they founded the Veterans Smile Day Foundation. As cochair, Jaci has spent the past six years working with our nations veterans and dental providers across the nation to deliver free dental care to the men and women who have served selflessly for our country but who do not receive dental benefits. Each year you will find her offering her expertise to the local veterans for free to help make a difference in their oral care and overall health. She strongly believes in helping our veterans live a better life.

The Veterans Smile Day Foundation is a nonprofit 501(c)(3) whose mission is to recruit dental professionals and corporate sponsorships to help fill in that void by Serving Those Whove Served. Since its inception in 2012, it has grown to include private dental offices, dental schools, hospitals, and dental societies throughout the United States.

Jaci invites you to volunteer with the Veterans Smile Day Foundation. Find out how you can use your dental hygiene skills to serve those whove served by contacting Jaci at jaciklepadlo@gmail.com. Because Jaci followed her passion for serving our veterans, she has become a recipient of the 2020 Sunstar/RDH Award of Distinction.

Congratulations, Jaci Klepadlo!

(Pennsylvania)

Mentoring, educating, creating systems within the dental office, igniting passion in dental hygienists, meeting challengesthese are all aspects of Lisandra Lisandra Maisonet, BS, RDH, PHDHP, EFDAMaisonets present day-to-day life. But she began her career as a clinical hygienist in a pediatric dentistry practice. In that capacity, Lisandra implemented a strong preventive protocol that led to an incredible decrease in dental disease in the practice. She was able to inspire every team member to actively participate in the efforts to improve the oral health of thousands of patients.

While working in both the preventive and restorative aspects of dentistry and assisting in IV sedation cases in the pediatric practice, Lisandra questioned why they were treating a disease that was totally preventable. Answering this question became the driving force that brought her to her current role as director of operations and hygiene and leader to 50 dental hygienists in 22 practices, where she has created strong systems that focus on disease prevention and education on oral-systemic health.

Lisandra has made a positive impact on her community in many ways. She is an educator for the Healthy Teeth Healthy Children program, where she goes to pediatricians offices and educates medical professionals on the importance of oral health and fluoride application. She is a volunteer for Mission of Mercy, providing dental care to the underserved in her state, and she has presented numerous courses for the Cavity Free Kids program in Pennsylvania to educate the community on the importance of oral health.

During her active membership with the Pennsylvania Dental Hygienists Association (PDHA), Lisandra served as president for three years. In that time, she worked hard to push initiatives forward to enhance the profession of dental hygiene. She mentors and inspires hygienists to become involved and serve in their association.

With financial help from the PDHA, Lisandra was given the opportunity to create a video that highlights the dental hygienist. While working diligently on this video, she was diagnosed with an autoimmune disorder and hospitalized. Nevertheless, Lisandra continued with editing of the video with the desire to leave it as a legacy at the end of her PDHA presidency. The goal of the video was to share with patients and legislators the fact that dental hygienists are educated preventive specialists who are willing and capable of providing care to the most vulnerable populations. While daunting at times, her passion for this project was what kept her going through difficult times. Lisandras hope is that, through this video, hygienists will finally gain the respect they deserve.

Because Lisandra followed her inner drive to make a difference on so many levels, she has become a recipient of the 2020 Sunstar/RDH Award of Distinction.

Congratulations, Lisandra Maisonet!

(Raleigh, North Carolina)

Karen Thomas began her career as a clinical dental hygienist in Florida. She later became a research dental hygienist at the University of North Carolina at Chapel Hill and was the examiner for patients with temporomandibular disorder (TMD), fibromyalgia, chronic fatigue, episodic headaches, and pelvic pain. It broke her heart to see patients in so much pain. As an examiner, she gathered data but did not have the opportunity to make a personal connection with the Karen Thomas, MSc, BS, RDH, CNS, LN, ND, FDN-P, CHHC, Biological RDHpatients. She thought, Thereve got to be better ways to help these people.

Then, life took a turn in Karens career and her health. Her future mother-in-law became seriously ill days before her wedding. Over a short period of time, the house she was selling caught fire the day before closing, her father passed away, her new home needed significant renovations, and her new husband ended up in the hospital. Karen was told he would not make it. Unfortunately, her mother-in-law did pass on, but Karens husband came home from the hospital and is fine today.

The stress became too much to bear and, as Karen puts it, her body simply shut down. She took a medical leave from her job and spent the next two years in bed, doing little more than sleeping.

After two years of doctors appointments, 15 different diagnoses, multiple medications, and still no improvement, Karen took matters into her own hands. She had been diagnosed with Hashimotos thyroiditis as a teenager. Karen found research stating that 2%5% of people with Hashimotos also have celiac disease, but no doctor had tested her for that. Karen ordered tests on her own and presented the results to her doctor, who finally diagnosed her with celiac disease. She gave up gluten, among several other dietary changes, and got her life back. As one of her nominators for the award said, Thankfully, the dental hygiene curriculum and the way we as RDHs are taught to decipher information are ultimately what helped her heal herself through food.

Karen had regained her life but still wanted to help others. She went back to college to learn more about integrative medicine and combined that education with her dental hygiene training to help others link oral health with systemic health. She attained a master of science in human nutrition and functional medicine and became a licensed nutritionist, a certified nutrition specialist, a certified integrative nutrition health coach, and a certified functional diagnostic nutrition practitioner. Karen is also the award-winning author of Overwhelmed and Undernourished: Use Food as Medicine and Turn Your Life Around. She currently works as a functional medicine nutritionist and teaches continuing education in dentistry.

It is easy to see why Roy T. Bennett's quote is one of Karens favorites: Your hardest times often lead to the greatest moments of your life. Keep going. Tough situations build strong people in the end.

Congratulations, Karen Thomas!

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Recipients of the Sunstar|RDH Award of Distinction 2020 | Registered Dental Hygienist - RDH

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Meet This Year’s Be Well Philly Health Hero Finalists – Philadelphia magazine

November 5th, 2020 9:52 am

News

You can vote now for the winner of the 2020 Health Hero challenge.

You can start voting right now for the winner of the 2020 Be Well Philly Health Hero Challenge.

Were thrilled to announce that we now have our three finalists for the 2020 Be Well Philly Health Hero Challenge presented by Independence Blue Cross. Here at Be Well Philly, we constantly strive to highlight people who are helping others in the greater Philadelphia area live healthier and better lives. The Health Hero Challenge is our way of honoring the incredible and often unseen work that people do every day, even in the most challenging of circumstances.

We set out at the beginning of this challenge looking for medical providers, nonprofit leaders, entrepreneurs, teachers, anyone really whos making a difference in our community from a health and wellness perspective. And, you all delivered. You shared powerful personal stories of the heroes making a difference in our community, which led to to the nomination of these three finalists. Now, its time to choose the winner.

Name: Asasiya Muhammad (@thepeoplesmidwife), womens health advocate and midwife at Inner Circle Midwifery (@innercirclephilly), a private home birth practice based in Germantown.

Nonprofit of choice: Maternity Care Coalition. Since 1980, Maternity Care Coalition has assisted more than 135,000 families throughout Southeastern Pennsylvania, focusing particularly on neighborhoods with high rates of poverty, infant mortality, health disparities, and changing immigration patterns. A familys needs change as they go through pregnancy and their childs first years, and MCC offers a range of services and programs for every step along the way.

What motivates you to try to make Philadelphia a healthier place, and what policy would you institute if you could? I cherish Philadelphia as the place where I have had my most life-shaping experiences, some high such as graduating college, becoming a mother, and raising a family and others low. Ive had experiences that have left me feeling isolated, lost, and voiceless. As a Black mother, I have faced the feelings of fear and uncertainty many Black women in Philadelphia face, because of the haunting statistic that we are two times more likely to die during pregnancy, or within a year of giving birth due to pregnancy-related complications. As a midwife, I understand that the majority of these complications are preventable, and therefore have made it my mission to build a community-based a practice that is committed to diminishing this disparity in Philadelphia. My practice is unique in that it has a wraparound care component that bundles nutritional counseling and fitness classes into standard midwifery care.

I would institute a policy that expanded the use of and access to community-based providers and particularly related to those specializing in natural health and food access. This would look like expanding insurance access to providers like midwives, doulas, nutritional counselors, and fitness experts so that these services are both normalized and accessible to a larger part of the population. This would further look like creating sustainable food cooperatives in neighborhoods that are distant from larger markets and who now rely on stores that mostly carry processed foods.

Name: Vicky Borgia, a local doctor who utilizes Direct Primary Care (DPC), an alternative payment model for healthcare services. She specializes in reproductive health, LGBTQIA health and integrative medicine.

Nonprofit of choice: Womens Medical Fund. Racial justice and reproductive justice issues are intertwined. In 1976, Congress banned federal Medicaid coverage for abortion through the Hyde amendment. Then, in 1985, Pennsylvania prohibited state Medicaid coverage for abortion. Since then, Womens Medical Fund has provided funding to thousands of individuals struggling to get by and enrolled in Medicaid. Womens Medical Fund has expanded their mission to include advocacy and community organizing.

What motivates you to try and make Philadelphia a healthier place, and what policies would you institute if you could? I believe that healthcare is a human right. I serve communities that have historically been medically disenfranchised because I can use my skills and education to make changes in a system rife with health inequities. I center access, inclusion and equity in my direct primary care practice, which enables me to take the time I need with my patients and give the care they deserve.

Since it is well-established that racism and other forms of systemic oppression are major factors in increased morbidity, mortality, and generational trauma for all, my policy recommendations focus on dismantling systems of oppression in Philadelphia. This includes reprioritizing city investments from policing and instituting PILOTS where big health and educational nonprofits would volunteer a portion of their revenue to the general fund. These resources could be then be used to fund education and invest in communities by improving access to services, opportunities, food, and healthcare.

Name: Christy Silva, cofounder of Aidans Heart Foundation, a nonprofit committed to providing awareness, education, and support to the communities of the southeast Pennsylvania region and its surrounding area to create heart-safe communities for youth regarding the prevention of, or response to, tragic instances of Sudden Cardiac Arrest.

What motivates you to try to make Philadelphia a healthier place and what policy would you institute if you could ?

My motivation for wanting to make Greater Philadelphia a healthier place actually comes from a tragedy in my family. In September of 2010, my seven-year-old son Aidan, who had no prior health conditions, died without warning from sudden cardiac arrest, or SCA. I had never even heard of SCA prior to his death. As I struggled with my grief and tried to understand why my seemingly healthy child collapsed one sunny Saturday, I plunged into research. I learned that, nationally, approximately one out of every 300 youth has an undetected heart condition that could cause SCA. The American Heart Association quotes that more than 7,000 children under age 18 are struck by SCA each year. This equates to one young person, nearly every hour, every day, every year. Its a little known fact that Sudden Cardiac Arrest (SCA) is the leading cause of death in student athletes on school grounds. As a result of what I learned, I became determined to still be Aidans mom and try to prevent SCA from taking more young lives in our local communities. Im motivated by these facts to do everything possible to decrease the number of preventable deaths in young people in Philadelphia and its surrounding suburbs. I co-founded Aidans Heart Foundation shortly after Aidans death. To date, we have placed 89 AEDs in youth based sports facilities, trained 6,100 youth on how to perform CPR and how to use an AED, and we have partnered with pediatric cardiologists to provide 2,100 free heart screenings to kids and teens in efforts to detect heart conditions through a simple, non-invasive ECG exam.

If I could institute a policy to make Greater Philadelphia a healthier region, it would center around protecting hearts. Annual electrocardiogram exams at every well-child visit, particularly for young athletes; CPR and AED training for all teachers, coaches, instructors, etc. who work with physically active youth; and AED devices available in all schools, child care centers, dance, martial arts, gymnastics and other studios where kids are active, in addition to AEDs being prominently placed on every athletic playing field. These arent impossible tasks, but they do take the awareness of the public, particularly parents, to urge our community leaders and policymakers to implement these measures. We owe it to our kids to keep them safe at play.

Vote now to select your 2020 winner. Remember: the winner will be named the 2020 Health Hero and will receive a $15,000 donation to her charity of choice, and the two runners-up will each receive $2,500 donations to the charities of their choice.

Vote HERE now. (Remember, you can vote once a day until November 16th!) Stay in touch with @bewellphilly and @phillymagevents.

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Meet This Year's Be Well Philly Health Hero Finalists - Philadelphia magazine

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17 Breathing Videos That Will Help You Relax and Unwind – Self

November 5th, 2020 9:52 am

In an already high-stress year, this week just might take the top spot. Theres no easy way to calm down fast, but taking time to do some guided breathingwith the help of handy breathing videosmight help you feel a little better.

For many of us, the months leading up to Election Day have been a source of long-term, slow-burning stress, Christiane Brems, Ph.D., a registered yoga teacher, clinical professor, and director of YogaX at Stanford Psychiatry, tells SELF. This type of stresssustained and low gradecan wreak havoc on our nervous system, she says.

When your body is stressed, it releases the stress hormones adrenaline and cortisol, kicking off your fight-flight-freeze response, Manuela Kogon, M.D., clinical associate professor at the Stanford Center for Integrative Medicine, tells SELF. But purposeful breathing can trigger your parasympathetic system, or the part of your autonomic nervous system that opposes the fight-flight-freeze response. As a result, it may help you feel rested and relaxed.

Breathing is so powerful because unlike so many things in life, it's something we have control over, Rachel Allyn, Ph.D., a psychologist and yoga teacher based in Minneapolis, tells SELF. By improving the way you breathe, you can shift your nervous system from the stress-response mode to a state of regulation and relaxation.

And the good news is you dont need to do an extensive breathing routine to get the benefitsand you dont need to do them for a prolonged amount of time, either.

In fact, you can feel calming benefits in as little as 30 seconds of purposeful breathing exercises, Catherine Cook-Cottone, Ph.D. a licensed psychologist and registered yoga instructor based in Buffalo, New York, tells SELF. It doesnt need to be complicated, she says. Orienting back to your own breathjust noticing itis a powerful first step.

For a little more structure, check out these 17 expert-approved breathing videos to help you get started.

Length: 9 minutes

What to expect: This guided meditation cultivates focus and stability through concentration and mindfulness with breathing.

I like this simple technique of paying attention to the gap between your exhale and inhale. It is so calming and the time floats by, leaving you feeling clear and aware when complete. Diane Malaspina, Ph.D, psychologist, yoga teacher, and therapeutic specialist in Virginia Beach, Virginia

Try the breathing routine.

Length: 3 minutes

What to expect: Gabby Bernstein, New York Times best-selling author and kundalini yoga and meditation teacher, shares a calming five-count breathing technique.

This three-minute video is great for a technique called box breath, where we silently count to five on the inhale, hold the inhale to a count of five, exhale for five, and hold our breath for a count of five (before the next inhale to a count of five). Beyond the immediate sense of calm it brings, the box breath is easy to do anywhere and enhances feelings of relaxation and peace. Diane Malaspina

Try the breathing routine.

Length: 4 minutes

What to expect: Thich Nhat Hanh guides you through the first exercises of mindful breathing, from following the in breath and out breath all the way through to generating the energy of mindfulness by being with your body.

I love this video because Thich Nhat Nahn, one of the most profound teachers, makes the breathing exercises simple and approachable. With these practices, we find the magic in the simple act of breathing. Laurasia Mattingly, meditation and mindfulness teacher and founder of the Sit Society in Los Angeles

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Maui Grown Therapies to Organize a Webinar on Cannabis Hosted by Dr. Andrew Weil on November 5 – London Daily Post

November 5th, 2020 9:52 am

Maui Grown Therapies has announced to organize a webinar titled, Cannabis and the Anti-Inflammatory Lifestyle that is going to be held on November 5. There are no charges imposed on participation in this webinar. The event will take place from 11:00 (HST) to 2:00 (PST) and it will be presented by Dr. Andrew Weil.

Andrew Weil is the MD, founder, and director of the Andrew Weil Center for Integrative Medicine at the University of Arizona. In addition to this, he is the chief science officer for Maui Grown Therapies. He has always endorsed the importance of living an anti-inflammatory lifestyle to get rid of many health problems.

In the webinar, Cannabis and the Anti-Inflammatory Lifestyle, participants will learn important information about reducing inflammation. Moreover, they will know about the ways to boost the natural defense mechanisms of the body.

Additionally, the light will be thrown on the subject of the importance of various compounds present in the cannabis plants namely, CBD, THC, and terpenes. The webinar will conclude with a live Q&A after the online presentation on the subject of living an inflammatory lifestyle.

Dr. Andrew Weil has been endorsing the anti-inflammatory lifestyle for a long time. He conducted the first human trials in the nation using various cannabis products. Dr. Weil has gained global recognition for his worthy contribution to integrative medicine.

He completed his undergraduate degree in botany from Harvard and gained his M.D from Harvard Medical School. Dr. Weil always endorses the consumption of cannabis seeds to gain healthy fats and essential fatty acids.

He is associated with Maui Grown Therapies, Hawaiis first state-licensed medical cannabis dispensary, to spread awareness about living an anti-inflammatory lifestyle by consuming various cannabis products. Know more about the webinar and register for the webinar by clicking the links mentioned below.

Register for the Webinarhttps://manao.mauigrown.com/maui-grown-manao

Youtube Linkhttps://www.youtube.com/watch?v=yz8ryqanQDM

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YOUR GUIDE TO CANNABIS & THE ANTI-INFLAMMATORY LIFESTYLE

Your Guide to Cannabis and an Anti-Inflammatory Lifestyle by THE MEDIA BUTLER

Address

Maui Grown Therapies44 Paa St, Kahului, HI 96732(808) 866-7576

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Maui Grown Therapies to Organize a Webinar on Cannabis Hosted by Dr. Andrew Weil on November 5 - London Daily Post

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Synthace and Ipsen Partner to Accelerate Novel Therapeutic Development Through Automation – BioSpace

November 5th, 2020 9:52 am

Nov. 5, 2020 09:00 UTC

BOSTON & LONDON--(BUSINESS WIRE)-- Synthace Ltd and Ipsen, a global biopharmaceutical company focused on innovation and specialty care, have partnered to accelerate development of novel biotherapeutics targeting multiple therapeutic areas, including oncology, endocrinology, pain management, regenerative medicine and rare diseases. Ipsen has automated design and construction of therapeutic candidates using Synthaces integrative software platform, Antha. The process aims to speed up biotherapeutic candidate entry into the screening pipeline and shorten development time for treatment of diseases via targeted secretion inhibition.

Ipsen has developed novel biotherapeutic molecules, called Targeted Secretion Inhibitors (TSIs). TSIs are a fusion of select parts of the botulinum neurotoxin with another protein domain to redirect its mode of action, resulting in a unique targeted therapeutic. The design and construction of TSIs is both labour intensive and manually complex, typically taking 30 days to develop between 24-48 constructs which then go on to therapeutic screening.

The Ipsen R&D team required a solution to increase throughput and efficiency of its TSI generation and screening pipeline, while utilizing its Type IIs construct assembly method. They looked to fellow innovators Synthace, whose flexible and integrative software Antha has built-in workflows for automating processes such as Type II construct assembly, bacterial transformation, plating, data generation and analysis.

Synthaces Antha platform allowed the Ipsen team to plan, simulate, and test their assemblies in silico before executing the protocol. The partnership of Antha and Ipsen produced approximately 90 constructs five times faster than previous methods, substantially increasing the number of molecules entering the screening cascade. Antha was also able to increase efficiency by re-using core DNA building blocks for multiple construct assemblies, resulting in a 10-fold reduction in costs associated with DNA synthesis.

Dr. Karen Bunting, Director of Protein Science at Ipsen said, The development of novel biotherapeutics like TSI is key to treating debilitating illnesses across multiple therapeutic areas. The first step in this is generating and screening high quality molecules as therapeutic candidates. Using Antha, our team increased throughput at this crucial step, allowing us to design, construct, and screen novel TSI candidates rapidly and helping to advance our therapeutic solutions.

Drug discovery is a costly and laborious process where thousands of candidates are generated, screened and validated, but only a select few are chosen to move forward in the pipeline. Pharma companies are turning to automation and software to aid in the design, construction and screening of these compounds, reducing costs and increasing efficiency without compromising on quality.

To achieve this, biopharmaceutical companies like Ipsen are partnering with specialists in integrating the digital and physical aspects of R&D, providing an easy-to-use interface between scientists, design software, automated devices, and data handling downstream. This flexible, integrated approach to the discovery process has clear advantages in boosting efficiency at the earliest stages of drug development, with the ultimate goal of making more effective treatment options available to patients sooner.

Dr. Tim Fell, CEO of Synthace concluded, We are thrilled to see our Antha platform applied to develop new biotherapeutics. Antha has accelerated Ipsens TSI construction and screening programme while reducing costs and the time scientists spent in the lab. Automating processes like these allows scientists to focus on experimental design and data analysis rather than liquid handling, enabling them to create more beneficial therapeutics for patients,.

To learn more about automating drug discovery and development protocols, visit: https://www.synthace.com/customers/case-studies/detail/construct-assembly-for-the-development-of-new-therapeutics-with-ipsen/

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About Synthace Based in London, UK and Boston, US, Synthace is accelerating biological discovery & optimization through computer-aided biology. Our cloud software platform, Antha, empowers biologists by enabling them to flexibly program their lab automation without the need to code. The graphical user interface has been designed by biologists for biologists, intuitively enabling them to automate their whole experiment from planning to execution, data collection and analysis. Antha is the cornerstone of the lab of the future, seamlessly connecting the digital realm of data with the physical of lab automation and wet-lab biology, automatically collecting and structuring data to accelerate biological understanding.

Synthace is unlocking the potential of biology for humankind and our environment. Synthace works with biopharmaceutical companies, and in 2016 was recognized by the World Economic Forum as a Technology Pioneer that is helping shape the Fourth Industrial Revolution, and in 2018 as a cool vendor by Gartner.

View source version on businesswire.com: https://www.businesswire.com/news/home/20201105005418/en/

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Specialdocs Informs and Inspires at Concierge Medicine Industry’s Signature Event Nov. 12th – 14th – Benzinga

November 5th, 2020 9:52 am

CHICAGO, Nov. 3, 2020 /PRNewswire/ --At the 2020 Concierge Medicine Forum (CMF), Terry Bauer, CEO of Specialdocs Consultants, a pioneer in concierge medicine transitions and management, along with a group of the company's outstanding physician-clients, will share an inside look at the practice model that continues to fuel one of the healthcare industry's rare success stories in a year of unprecedented challenge. A completely virtual experience for the first time, the highly anticipated annual industry event spans three days of presentations, workshops and live chat sessions with concierge industry leaders; all focused on the relevant theme of collaboration in medicine.

"At this pivotal point in healthcare, we are privileged to share our collective experience and stories of transformation."

"This year has exposed the vulnerabilities of traditional fee-for-service practices in ways we could never have foreseen," says Bauer. "And 2020 has also underscored the resilience and rewards of the Specialdocs model of personalized medicine and inspired rising numbers of physicians to consider this beneficial alternative for themselves and their patients. At this pivotal point in American healthcare, we are privileged to share with Concierge Medicine Forum attendees our collective experience and first-person stories of transformation from our network of dedicated doctors."

Michael Tetreault, CMF organizer and editor of Concierge Medicine Today, says: "The virtual format enables us to host a more diverse gathering of healthcare professionals than ever before, and offer 24/7 on-demand access to insights from the industry's most creative minds. We're thrilled to feature groups like Specialdocs, pioneers and continual innovators in the concierge medicine space."

Specialdocs will be featured at events including: (all ET)

Thursday, Nov. 12th Pre-conference workshop

Friday, Nov. 13th

After 2 pm

Saturday, Nov. 14th

Since 2002, concierge medicine transition and management experts Specialdocs Consultants have helped physicians nationwide transform their practices with a uniquely customized and sustainable concierge model.

Contact: Mindy Kolof, mkolof@specialdocs.com

View original content to download multimedia:http://www.prnewswire.com/news-releases/specialdocs-informs-and-inspires-at-concierge-medicine-industrys-signature-event-nov-12th--14th-301166040.html

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Maui Grown Therapies’ Webinar, Cannabis and the Anti-inflammatory Lifestyle to be Held on Nov. 5 – California Herald

November 5th, 2020 9:52 am

Maui Grown Therapies webinar titled, Cannabis and the Anti-Inflammatory Lifestyle is scheduled to take place on November 5. It will be presented by Andrew Weil who is MD, founder, and director of the Andrew Weil Center for Integrative Medicine at the University of Arizona and chief science offer for Maui Grown Therapies.

Maui Grown Therapy is Hawaiis first state-licensed medical cannabis dispensary. The timing of the webinar is set at 11:00 (HST) to 2:00 (PST) on Thursday, Nov. 5, 2020. The webinar will highlight the importance of living an anti-inflammatory lifestyle to improve overall health and wellness. It will end with a live Q&A post the online presentation.

Dr. Andrew Weil has always supported the anti-inflammatory lifestyle to live a healthy life. He is globally renowned for his pioneering work in integrative medicine. He earned his undergraduate degree in botany from Harvard and he completed his M.D. from Harvard Medical School. It was in 1969 when Dr. Weil conducted the nations first human trials with the use of cannabis.

The participants of the webinar, Cannabis and the Anti-Inflammatory Lifestyle will learn ways to reduce inflammation and boost the natural defense mechanisms of the body. In addition to this, the value of compounds in cannabis plants such as CBD, THC, and terpenes will also be discussed.

Dr. Weil also recommends consuming cannabis seeds (edible hemp seeds) as a rich source of healthy fats and essential fatty acids. They are an excellent protein source that contains vitamin E, phosphorus, potassium, sodium, magnesium, sulfur, calcium, iron and zinc.

Register for the Webinar https://manao.mauigrown.com/maui-grown-manao

Youtube Link https://www.youtube.com/watch?v=yz8ryqanQDM

Read More Here

YOUR GUIDE TO CANNABIS & THE ANTI-INFLAMMATORY LIFESTYLE

Your Guide to Cannabis and an Anti-Inflammatory Lifestyle by THE MEDIA BUTLER

Address

Maui Grown Therapies44 Paa St, Kahului, HI 96732(808) 866-7576

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Maui Grown Therapies' Webinar, Cannabis and the Anti-inflammatory Lifestyle to be Held on Nov. 5 - California Herald

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Daylight Saving Time: What happens to your body when we fall back – Yahoo Canada Shine On

November 5th, 2020 9:52 am

Daylight saving time ends on Nov. 1 at 2 a.m. While many simply see this as gaining an hour of sleep on Sunday, there are various lasting effects that this time change will bring, both mentally and physically. Yahoo Life is joined by two experts who share what to expect and ways to combat the negative effects.

Integrative medicine physician and wellness expert Dr. Taz Bhatia explains that when we set the clocks back, were also adjusting our internal clock and throwing off our circadian rhythm.

Our circadian rhythms, or the flow of when we sleep and when were awake, dictates so many different processes in the body, says Bhatia.

When our circadian rhythms are thrown off, our sleep cycles become inconsistent, our weight is less regulated due to a change in insulin, and the risk of heart disease, stroke and heart attack increases.

Judy Ho, a licensed clinical and forensic neuropsychologist, highlights how experiencing one less hour of light each day can heavily impact ones mood, causing us to experience more depression and sadness.

So what can we do to cope with these changes? During the day, its crucial to take advantage of any kind of sunlight, whether its indirectly through a window or through a sun lamp as light therapy has been proven to work wonders on mood and sleep.

With less sunlight during the day, we also receive less vitamin D, also known as the sunshine vitamin. We can, however, make up for the lack of vitamin D in other ways. It's important now more than ever to exercise regularly, as it helps with the endorphin release and boosts our mood, says Bhatia.

Ho recommends establishing a calming nighttime routine that involves putting away all devices, especially blue light devices. To combat sleep deprivation, people should go to bed earlier, but not too early.

You dont want to go to bed too early just to make sure that youre in bed by a certain hour because then you might be awake for longer than you need to be, Ho explains. Then the bed becomes associated with anxiety and stress.

Since 2020 has been anxiety-inducing for many, Bhatia points out that our threshold for anxiety and depression is lower right now.

When we have additional disruptions like disruptions to our sleep cycle, disruptions to the amount of light we're getting in when we're awake, its just one more factor in an already really tough year for so many people, she says.

Ho reiterates how beneficial it is to maintain social connections on a daily basis with friends and loved ones.

Even a brief interaction like that can bring you a lot of positivity and feeling of community when you need it most, she says.

Video produced by Jenny Miller

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Who are this year’s Best of the Press? – Press of Atlantic City

November 5th, 2020 9:52 am

On Oct. 14 2020, in Ocean City, Car Caress was named Best Auto or Boat Detailer for this years Best of The Press contest.

When you buy a new car, it has that crisp, clean smell of wax, leather and upholstery. But over time, that fresh scent can be overtaken by cigarettes, fast food, spilled coffee and pet odors.

If the thought of cleaning your car seems overwhelming, take it to Car Caress Custom Auto Detailing, which earned Best of the Press in the Automotive/Transportation category.

Owner Brian Coggins is honored by the accolade and owes his success to his employees.

Customer services is No. 1, and that makes all the difference. I have a good group of people working for me, he says. I cant do everything myself. They do a great job.

With three locations Ocean City, Marmora and Somers Point Car Caress restores vehicles with services that shine, buff, polish and freshen your car or boat, inside and out.

Services include detailing; ceramic coating, a longer-lasting way to protect the paint than wax alone; ozone treatment, which disinfects and destroys bacteria in your car and the ventilation system; and automatic car washing.

Car detailing along with these other services requires a desire for perfection.

You have to be picky to do this kind of work, says Coggins. Youre not there just to make it look OK. You want to get the car or boat looking perfect. So you have to get into all the cracks and crevices.

It also takes skill, particularly buffing the car or boat.

Buffing isnt using a rag to shine something, Coggins explains. Theres a high-speed rotary buffer that runs at 1,500 rpms to 2,000 rpms. Using this machinery requires real craftsmanship, says Coggins, because if you dont know what youre doing, you can scratch the car and do damage.

For these reasons, Coggins is grateful most of his 15 employees stayed with him, even while his business was closed during quarantine.

Although COVID-19 sidelined Car Caress, it has created a silver lining for the family-owned business, namely sanitizing vehicles. Coggins explains the difference between cleaning and sanitizing.

With sanitizing, youre killing the germs and bacteria that are on the surfaces of whatever youre cleaning. When youre cleaning with a regular soap, youre not necessarily killing all the germs, he says.

Thats where ozone cleaning comes in, a service thats becoming increasingly more popular now that COVID-19 is a way of life. Ozone is a gas that removes odors, as well as disinfects and destroys viruses and bacteria. Unlike a liquid disinfectant, ozone gets into the places you cant clean, including the ventilation and AC systems, carpet fibers and upholstery.

Customers are requesting this service more, as well as used car dealerships, and those in the private transportation business, such as Uber drivers.

Although coping with COVID-19 was difficult during quarantine, Coggins biggest challenge still is operating a seasonal business.

Summers are super busy here, he Coggins. We hire summer workers, and it takes a while for them to learn. Just when they start getting good at this, they go home and leave.

Thats why Coggins is grateful to his employees, who take the sting out of summer workers departures.

The guys I have are really good, and most came back after quarantine, which was nice. I owe this (Best of The Press) to them, he says.

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AbbVie to Highlight Blood Cancer Leadership and Advancing Oncology Pipeline at the ASH 62ND Annual Meeting – WFMZ Allentown

November 5th, 2020 9:52 am

NORTH CHICAGO, Ill., Nov. 5, 2020 /PRNewswire/ --AbbVie (NYSE: ABBV) announced that it will present blood cancer data from nearly 40 abstracts, including 10 oral presentations, across 11 cancer types during the upcoming virtual American Society of Hematology (ASH) Annual Meeting and Exposition, December 5-8.

"We are steadfast in our commitment to advancing discovery, innovation and care for people with blood cancers," said Mohamed Zaki, M.D., Ph.D, vice president and global head of oncology development, AbbVie. "We are looking forward to sharing findings from our expanding hematology oncology portfolio and continued research and treatment advances during the ASH annual meeting."

AbbVie will present updated results from the CAPTIVATE study, evaluating disease-free survival in previously untreated patients with chronic lymphocyctic leukemia (CLL)/small lymphocytic leukemia (SLL) who received an ibrutinib (IMBRUVICA) + venetoclax (VENCLEXTA/ VENCLYXTO) combination regimen. As well, an update on a 5-year analysis of the MURANO study in a subset of relapsed/refractory CLL patients following venetoclax-(VENCLEXTA/ VENCLYXTO) rituximab therapy and 8-year follow-up ibrutinib (IMBRUVICA) data in high-risk patients with CLL (RESONATE-2 and iLLUMINATE) will be presented. AbbVie's new partners, Genmab and I-Mab will offer data from recently announced collaborations.

Details about presentations are as follows:

Abstract

Presentation Details

All times CT

Ibrutinib

Ibrutinib (Ibr) Plus Venetoclax (Ven) for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL): 1-Year Disease-Free Survival (DFS) Results From the MRD Cohort of the Phase 2 CAPTIVATE Study

Session 642. CLL: Therapy, excluding TransplantationSaturday, December 5Session: 9:30 a.m. - 11:00 a.m.Oral Presentation: 11:30 a.m.

Five-Year Follow-Up of Ibrutinib Plus Rituximab vs Placebo Plus Rituximab for Waldenstrom's Macroglobulinemia: Final Analysis From the Randomized Phase 3 iNNOVATE Study

Session 623. Mantle Cell, Follicular, and Other Indolent B-Cell LymphomaClinical Studies: Clinical studies in Waldenstrom's Macroglobulinemia, Marginal Zone Lymphoma and Hairy Cell LeukemiaSunday, December 6Session: 9:30 a.m. - 11:00 a.m.Oral Presentation: 11:30 a.m.

Rarity of B-Cell Receptor Pathway Mutations in Progression-Free Patients With Chronic Lymphocytic Leukemia (CLL) During First-Line Versus Relapsed/Refractory (R/R) Treatment With Ibrutinib (Ibr)

Session 642. CLL: Therapy, excluding Transplantation: Poster II

Sunday, December 6

Outcomes of First-Line Ibrutinib in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and High-Risk Genomic Features With Up To 6.5 Years Follow-Up: Integrated Analysis of Two Phase 3 Studies (RESONATE-2 and iLLUMINATE)

Session 642. CLL: Therapy, excluding Transplantation: Poster IISunday, December 6

Long-Term Efficacy of First-line Ibrutinib Treatment for Chronic Lymphocytic Leukemia (CLL) With 4 Years of Follow-Up in Patients With TP53 Aberrations (del(17p) or TP53 Mutation): A Pooled Analysis From 4 Clinical Trials

Session 642. CLL: Therapy, excluding Transplantation: Poster II

Sunday, December 6

Real-World Prognostic Biomarker Testing, Treatment Patterns and Dosing Among 1461 Patients (pts) with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) from the informCLL Prospective Observational Registry

Session 642. CLL: Therapy, excluding Transplantation: Poster IIMonday, December 7,Session: 7:00 a.m. 8:30 a.m.Oral Presentation: 10:15 a.m.

Ibrutinib Plus Venetoclax in Patients with Relapsed/Refractory Mantle Cell Lymphoma: Results From the Safety Run-In Period of the Phase 3 SYMPATICO Study

Session 623. Mantle Cell, Follicular, and Other Indolent B-Cell LymphomaClinical Studies: Poster III

Monday, December 7

Long-Term Follow-Up of Ibrutinib Treatment for Rituximab-Refractory Waldenstrm's Macroglobulinemia: Final Analysis of the Open-Label Substudy of the Phase 3 iNNOVATE Trial

Session 623. Mantle Cell, Follicular, and Other Indolent B-Cell LymphomaClinical Studies: Poster IIIMonday, December 7

Venetoclax in Acute Myeloid Leukemia (AML)

Venetoclax Crosses the Blood Brain Barrier: A Pharmacokinetic Analysis of the Cerebrospinal Fluid in Pediatric Leukemia Patients

Session 613. Acute Myeloid Leukemia: Clinical Studies: Poster I

Saturday, December 5

Venetoclax Alone or in Combination with Chemotherapy: Responses in Pediatric Patients with Relapsed/Refractory Acute Myeloid Leukemia with Heterogenous Genomic Profiles

Session 615. Acute Myeloid Leukemia: Commercially Available Therapy, excluding Transplantation: Poster I

Saturday, December 5

Proposed Scheme for Dosing Venetoclax in Pediatric Patients with Relapsed/Refractory Acute Myeloid Leukemia: Analysis of Developmental Pharmacokinetics and Exposure-Response Relationships

Session 613. Acute Myeloid Leukemia: Clinical Studies: Poster I

Saturday, December 5

Results of Venetoclax and Azacitidine Combination in Chemotherapy Ineligible Untreated Patients with Acute Myeloid Leukemia with IDH 1/2 Mutations

Session 613. Acute Myeloid Leukemia: Potpourri of Potential Practice Changing Studies

Sunday, December 6

Session: 9:00 a.m. - 5:30 p.m.

Oral Presentation: 4:45 p.m.

Efficacy and Safety of Venetoclax in Combination with Gilteritinib for Relapsed/Refractory FLT3-Mutated Acute Myeloid Leukemia in the Expansion Cohort of a Phase 1b Study

Session 613. Acute Myeloid Leukemia: Novel Therapies and Treatment Approaches

Sunday, December 6

Session: 9:00 a.m. - 5:30 p.m.

Oral Presentation: 12:15 p.m.

Cytopenia Management in Patients with Newly Diagnosed Acute Myeloid Leukemia Treated with Venetoclax Plus Azacitidine in the VIALE-A Study

Session 615. Acute Myeloid Leukemia: Commercially Available Therapy, excluding Transplantation: Poster II

Sunday, December 6

Characteristics and Outcomes of Newly Diagnosed Acute Myeloid Leukemia Patients Receiving Venetoclax Combinations vs Other Therapies: Results from the AML Real World EvidenCe (ARC) Initiative

Session 906. Outcomes ResearchMalignant Conditions (Myeloid Disease): Poster II

Sunday, December 6

Results of Venetoclax and Azacitidine Combination in Chemotherapy Ineligible Untreated Patients with Acute Myeloid Leukemia with FLT3 Mutations

Session 613. Acute Myeloid Leukemia: Clinical Studies: Poster IISunday, December 6

Real-World Treatment Patterns and Clinical Outcomes in Unfit Patients with AML Receiving First-Line Systemic Treatment or Best Supportive Care (CURRENT): Final Analysis

Session 613. Acute Myeloid Leukemia: Clinical Studies: Poster II

Sunday, December 6

First Results from a Nationwide Prospective Non-Interventional Study of Venetoclax-Based 1st Line Therapies in Patients with Acute Myeloid Leukemia (AML) REVIVE Study

Session 613. Acute Myeloid Leukemia: Clinical Studies: Poster III

Monday, December 7

CYP3A Inhibitors and Impact of These Agents on Outcomes in Patients with Acute Myeloid Leukemia Treated with Venetoclax Plus Azacitidine on the VIALE-A Study

Session 615. Acute Myeloid Leukemia: Commercially Available Therapy, excluding Transplantation: Poster III

Monday, December 7

Venetoclax in Acute Lymphoblastic Leukemia (ALL)

Venetoclax and Navitoclax in Pediatric Patients With Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Session 614. Acute Lymphoblastic Leukemia: Therapy, excluding Transplantation: Targeted Therapies

Sunday, December 6

Session: 9:00 a.m. - 5:30 p.m.

Oral Presentation: 4:30 p.m.

Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia Harboring Heterogenous Genomic Profiles Respond to Venetoclax in Combination with Chemotherapy

Session 612. Acute Lymphoblastic Leukemia: Clinical Studies: Poster III

Monday, December 7

Venetoclax in Chronic Lymphocytic Leukemia (CLL)

Five-Year Analysis of MURANO Study Demonstrates Enduring uMRD in a Subset of Relapsed/Refractory (R/R) CLL Patients Following Fixed Duration Venetoclax-Rituximab Therapy

Session 642. CLL: Therapy, excluding Transplantation

Saturday, December 5

Session: 9:00 a.m.- 5:30 p.m.Oral Presentation: 12:00 p.m.

Clonal Dynamics After Venetoclax-Obinutuzumab Therapy: Novel Insights From the Randomized, Phase 3 CLL14 Trial

Session 642. CLL: Therapy, excluding Transplantation

Saturday, December 5

Session: 9:00 a.m. - 5:30 p.m.

Oral Presentation: 12:30 p.m.

Characteristics and Outcome of Patients with Chronic Lymphocytic Leukaemia and Partial Response to Venetoclax-Oinutuzumab

Session 642. CLL: Therapy, excluding Transplantation: Poster I

Saturday, December 5

Assessment of Tumor Lysis Syndrome in Patients with Chronic Lymphocytic Leukemia Treated With Venetoclax in the Clinical and Post-Marketing Settings

Session 642. CLL: Therapy, excluding Transplantation: Poster II

Sunday, December 6

Efficacy of Subsequent Novel Targeted Therapies, Including Repeat Venetoclax-Rituximab (VenR), in Patients with Relapsed/Refractory CLL Previously Treated With VenR in the MURANO Study

Session 642. CLL: Therapy, excluding Transplantation: Poster III

Monday, December 7

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AbbVie to Highlight Blood Cancer Leadership and Advancing Oncology Pipeline at the ASH 62ND Annual Meeting - WFMZ Allentown

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Scientific Review on Social Determinants of Health and Diabetes – The Ritz Herald

November 3rd, 2020 6:58 pm

American Diabetes Association (ADA), the nations leading organization for all people living with diabetes, published a scientific review addressing social determinants of health (SDOH) and diabetes. Toward the goal of understanding and improving the health of people with diabetes through addressing SDOH, a writing committeeconvened by the ADAreviewed past evidence and research on diabetes risk and outcomes, as well as the impacts of interventions in these determinants.

People living with diabetes face many challenges. Some of these relate to the disease itself, but increasingly we recognize the importance of many social determinants, said Robert A. Gabbay, Chief Scientific and Medical Officer for the ADA. The scientific review not only defines these issues but shines a bright light on the resulting health disparities and articulates an important research agenda to address these issues. The release of this important scientific review underlines the American Diabetes Associations commitment for #HealthEquityNow.

As defined by the World Health Organization (WHO), social determinants of health are the conditions in which people are born, grow, live, work, and age. These circumstances are shaped by the distribution of money, power, and resources at global, national, and local levels. The social determinants of health are mostly responsible for health inequitiesthe unfair and avoidable differences in health status seen within and between countries. The COVID-19 pandemic has further exposed unequal vulnerabilities that impact racial and ethnic minority groups and disadvantaged communities. Understanding and mitigating the impact of SDOH for people with diabetes are priorities due to disease prevalence, economic costs, and disproportionate population burden.

The ADA committee summarized the following recommendations from international and U.S. national committees that have convened to provide guidance on SDOH intervention approaches:

This is a critical time in our nations history. As researchers and providers, we have the opportunity to advance solutions to the longstanding inequities that impact diabetes and other health conditions, said Dr. Felicia Hill-Briggs, past ADA President of Health Care and Education and Chair of the SDOH writing committee. Through this SDOH review, the American Diabetes Association is taking an important step toward acknowledging and setting the stage for the important research, policy, and implementation work that must be done in order to change the trajectory of inequity.

The paper begins with a general outline of key definitions and SDOH frameworks and includes a literature review that focuses primarily on U.S.-based studies of adults with diabetes and on five aspects of SDOH: socioeconomic status (education, income, occupation); neighborhood and physical environment (housing, built environment, toxic environmental exposures); food environment (food insecurity, food access); health care (access, affordability, quality); and social context (social cohesion, social capital, social support). The paper concludes with recommendations for linkages across health care and community sectors, diabetes research, and research to inform practice.

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Scientific Review on Social Determinants of Health and Diabetes - The Ritz Herald

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The role of microRNAs in the development of type 2 diabetes complications – DocWire News

November 3rd, 2020 6:58 pm

This article was originally published here

Curr Pharm Des. 2020 Nov 1. doi: 10.2174/1381612826666201102102233. Online ahead of print.

ABSTRACT

MicroRNAs represent a class of small (19-25 nucleotides) single-strand pieces of RNA, that are non-coding ones. They are synthesized by RNA polymerase II from transcripts which fold back on themselves. They mostly act as gene regulatory agents, that pair with complementary sequences on mRNA and produce silencing complexes, which in turn suppress coding genes at a post-transcriptional level. There is now evidence that microRNAs may affect insulin secretion or insulin action, as they can alter pancreatic beta cells development, insulin production, as well as insulin signalling. Any molecular disorder that affects these pathways can deteriorate insulin resistance and lead to type 2 diabetes mellitus (T2DM) onset. Furthermore, the expression of several microRNAs is up- or down-regulated in the presence of diabetic microvascular complications (i.e. peripheral neuropathy, nephropathy, retinopathy, foot ulcers), as well as in patients with coronary heart disease, stroke, and peripheral artery disease. However, more evidence is needed, specifically regarding T2DM patients, to establish the use of such microRNAs as diagnostical biomarkers or therapeutic targets in daily practice.

PMID:33138753 | DOI:10.2174/1381612826666201102102233

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The role of microRNAs in the development of type 2 diabetes complications - DocWire News

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HIV, Hepatitis-B Drugs Proven to Reduce Risk of Type 2 Diabetes – Clinical Advisor

November 3rd, 2020 6:58 pm

Among patients diagnosed with HIV-1 or hepatitis B, the adjusted risk of incident type 2 diabetes was 33% lower among those who had been exposed to nucleoside reverse-transcriptase inhibitor (NRTI) drugs compared with those not exposed, suggesting that NRTIs have the potential to be repurposed for diabetes prevention in the future, according to a study published in Nature Communications.

After examining patient data from the Veterans Health Administration (VHA) over a 17-year period, researchers concluded that NRTIs are associated with a reduced risk of developing type 2 diabetes after adjusting for sociodemographic factors and comorbidities. To confirm this finding among more diverse populations, researchers examined patient data from 4 additional insurance databases: Truven, PearlDriver, Medicare, and Clinformatics.

In the VHA database, a total of 79,744 patients had a confirmed diagnoses of HIV or hepatitis B and did not have a prior type 2 diabetes diagnosis; 12,311 of these patients eventually developed type 2 diabetes. NRTI users had a 34% reduced risk of developing type 2 diabetes.

In the Truven database, 1630 of 23,634 HIV-positive or hepatitis B-positive patients developed incident type 2 diabetes; NRTI users had a 39% reduced risk of developing diabetes compared to non-NRTI users. Similarly, 1068 of 16,045 eligible patients in the PearlDriver database developed type 2 diabetes; NRTI users had a 26% reduced risk. A total of 3097 Medicare patients were eligible; 707 of these patients developed type 2 diabetes, and NRTI users had a 17% reduced risk. Researchers identified 6341 eligible patients in the Clinformatics database, 1067 of whom developed type 2 diabetes. NRTI users in this group had a 27% reduced hazard of developing type 2 diabetes.

At 1, 2, 5, and 10 years of follow up, NRTI users maintained a reduced hazard of developing type 2 diabetes. In the VHA cohort, follow-up durations and mortality rates were comparable between NRTI users and non-users; researchers concluded that differences in mortality rates were not responsible for the observed risk reduction for type 2 diabetes among NRTI users.

Among patients in the VHA cohort who were hepatitis B-positive and HIV-negative, NRTI use was associated with a 28% reduced risk for developing type 2 diabetes. For HIV-positive and hepatitis B-negative patients, researchers observed a 38% reduced risk for type 2 diabetes in the veterans cohort.

With each additional year of using NRTIs, patients diagnosed with HIV-1 or hepatitis B in all 5 cohorts had a 3% to 8% reduced hazard of developing type 2 diabetes. Researchers could not establish a consistent association between other drug classes aside from NRTIs that are used to treat HIV or hepatitis B and incident development of type 2 diabetes.

Researchers then studied insulin resistance-induced human cells to observe the effects NRTIs have on non-HIV-positive or hepatitis B-positive patients, and concluded that NRTI drugs such as lamivudine, azidothymidine, and stavudine were effective in improving insulin resistance.

We find that NRTI exposure is associated with reduced development of type 2 diabetes in people and that lamivudine inhibits inflammasome activation and improves insulin sensitivity in experimental systems, concluded the study authors.

Disclosure: Multiple authors declared affiliations with the pharmaceutical industry. Please see the original reference for a full list of authors disclosures.

Ambati J, Magagnoli J, Leung H, et al. Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development. Nat Commun. 2020;11(1):4737.

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HIV, Hepatitis-B Drugs Proven to Reduce Risk of Type 2 Diabetes - Clinical Advisor

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Podiatrists Caution Patients with Diabetes Not to Avoid Care Due to Fear of COVID-19 – Herald-Mail Media

November 3rd, 2020 6:58 pm

BETHESDA, Md., Nov. 2, 2020 /PRNewswire/ -- As COVID-19 appears to be building momentum worldwide, America's podiatrists say they're treating some of the sickest patients of their careersbut those patients are not suffering from the coronavirus. Instead, they're patients with diabetes who have delayed care due to fear of exposure to the virus and are suffering serious complications, ranging from severe diabetic foot wounds to gangrene to sepsis. Data have shown amputation rates are anywhere from three to 10 times what they were prior to the pandemic.

Podiatrists witness parallel public health crisis as amputation rates skyrocket during COVID-19 pandemic.

The American Podiatric Medical Association (APMA) is marking November's Diabetes Awareness Month with a public education campaign designed to urge the 34 million Americans living with diabetes to keep their regular health-care appointments. The campaign, Keep Your Appointment, Keep Your Feet, will provide strategies for maintaining control of diabetes during the pandemic and information about when to seek care for a foot or ankle concern.

"People with diabetes are at high risk from COVID-19," said APMA President Seth A. Rubenstein, DPM. "They should absolutely take appropriate precautions, such as wearing masks in public and avoiding large gatherings. In addition to taking such precautions, they also must continue to monitor and care for their diabetes."

In fact, Dr. Rubenstein said, the risks of avoiding diabetes care are much higher than the risk of exposure to the coronavirus in a medical facility. Physicians' practices are taking extensive precautions to keep patients and providers alike safe during the pandemic. Safeguards include additional PPE, requirements for patients to wear masks, social distancing in waiting areas, temperature checks, pre-appointment questionnaires, disinfection between patients, and more. Virtual appointments may also be available.

"We're encouraging people with diabetes to keep their appointments to keep their feet," said Priya Parthasarathy, DPM, chair of the APMA Communications Committee. "During the pandemic, we want patients to stay active, stay alert, and stay in contact with their podiatrist."

Patients can stay active by engaging in regular exercise. They should stick to a sensible diet designed to help control their blood sugar and keep all their appointments with their diabetes care team. They can stay alert by being vigilant about daily foot exams, looking for changes in color or temperature of the feet and new injuries. They should wear shoes, even around the house. Patients can stay in contact by keeping their regular health-care appointments, especially with their podiatrist. If they notice a change in their feet or sustain an injury, they should contact their podiatrist immediately.

To learn more about the campaign, visit http://www.apma.org/diabetes.

The American Podiatric Medical Association (APMA) is the nation's leading professional organization for today's podiatrists. Doctors of Podiatric Medicine (DPMs) are qualified by their education, training, and experience to diagnose and treat conditions affecting the foot, ankle, and structures of the leg. APMA has 53 state component locations across the United States and its territories, with a membership of more than 12,500 podiatrists. All practicing APMA members are licensed by the state in which they practice podiatric medicine. For more information, visit http://www.apma.org.

Contact: Leon Valentinelvalentine@apma.org301-581-9221

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Podiatrists Caution Patients with Diabetes Not to Avoid Care Due to Fear of COVID-19 - Herald-Mail Media

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The Best Way to Prevent Diabetes: An Affordable Plant-Based Diet – The Beet

November 3rd, 2020 6:58 pm

November is National Diabetes Month.In the U.S., its estimated that some 30 million adults ages 18 and older are living with diabetes and 84 million with pre-diabetes. While these dire statistics arent going to change overnight, the power to change our health is in our hands, a new study says. One of the simplest things we can do to change our risk? Go plant-based.

Back in August, we reported on a study out of the University of Bergen in Norway, that found that plant-based diets help you metabolize glucose, lose weight (particularly for people who are overweight), and prevent the onset of type 2 diabetes. Now, were back with more encouraging news for implementing a plant-based diet as an affordable, effective way to ward off type 2 diabetes.

In a recent review published in Practical Diabetology titled The Affordability of a Plant-Based Eating Pattern for Diabetes, the papers author, nutritionist Meghan Jardine, MS, MBA, RDN, LD, CDCES, Associate Director of Diabetes Nutrition Education, Physicians Committee for Responsible Medicine, recommends that anyone at high-risk go plant-based and that doctors and nutritionists should make it clear that there are affordable options when ditching meat and dairy.

Plant-based eating has become more popular as a healthy eating pattern for the prevention and treatment of diabetes, Jardine writes. Both observational and interventional studies have reported that plant-based diets reduce diabetes risk as well as improve diabetes outcomes, she later states, referencing this 2016 comprehensive review on the use of a plant-based diet for management of type 2 diabetes.

Worth mentioning: When it comes to eating a plant-based for diabetes management or prevention, its important to consider carbohydrates. Its heavily processed, refined carbohydrateslike white bread and chipsyou want to avoid. As Jardine points out, A healthy, affordable, plant-based diet is high in [carbohydrates]. Patients with diabetes are often told to avoid foods high in carbohydrate, as these foods have the greatest effect on postprandial glucose levels. She also notes that studies, such as this 2017 study from the Journal of Geriatric Cardiology, show that a high intake of carbohydrates, such as whole grains and cereal fibers, are associated with a reduction in diabetes risk, whereas refined carbohydrates increase risk. (For more on healthy carb options, check out our guide to whole grains here.)

While vegan eating may have the rap as a costly lifestyle, as Jardine argues and research supports, eating a healthy, plant-based diet can actually be quite wallet-friendly, and even save you money compared to other dietary regimes with animal products. Some healthy, affordable plant-based options the piece suggests include apples, bananas, oranges, broccoli, spinach, carrots, whole wheat bread, rolled or steel-cut oats, quinoa, black beans, pinto beans, and peanut butter, to name a few.

Buying foods when theyre in season and purchasing items like fruits, vegetables, legumes, and grains in bulk can also go a long way in reducing spending. Ditto for shopping the frozen aisle for fruits and vegetablesjust make sure there is no added salt, sugar, or other icky ingredientsand loading up on vegan pantry items when they are on sale. (If youre looking for more ways to save, check out 7 Ways to Save Money on Your Vegan Grocery List, According to Nutritionists.)

Bottom line: Eating a high-quality, plant-based eating pattern can be affordable and palatable and may offer specific benefits in preventing and treating diabetes, including quality of life and psychological health, offers Jardine. Frequent consumption of animal products has been associated with obesity, type 2 diabetes, heart disease, certain types of cancer and overall mortality. A diet thats good for our health and good for our wallets? Well take it. Spread the word, and spread the overnight oats recipes, dear readers.

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The Best Way to Prevent Diabetes: An Affordable Plant-Based Diet - The Beet

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Determinants of Increased Serum Calprotectin in Patients with Type 2 Diabetes Mellitus – DocWire News

November 3rd, 2020 6:58 pm

This article was originally published here

Int J Mol Sci. 2020 Oct 29;21(21):E8075. doi: 10.3390/ijms21218075.

ABSTRACT

Circulating calprotectin is a potential biomarker for endovascular inflammation in type 2 diabetes mellitus (T2DM). We investigated the determinants of calprotectin and its relationship with the presence of cardiovascular disease (CVD) in 362 T2DM patients included in the Diabetes and Lifestyle Cohort Twente-1 (DIALECT-1) study. Lifestyle exposures, including nutrition, were determined by validated questionnaires. CVD was defined as coronary artery diseases, strokes, and peripheral artery diseases. Median serum calprotectin levels were 1.04 mg/L [IQR: 0.73-1.46 mg/L] and were higher in women (1.11 mg/L) than men (0.96 mg/L, p = 0.007). Current smoking was a major independent determinant of circulating calprotectin, with a 51% higher calprotectin compared to never smoking (p < 0.001). Albuminuria (p = 0.011), former smoking (p = 0.023), and intake of mono- and disaccharides (p = 0.005) also contributed independently to circulating calprotectin. Each incremental increase in calprotectin level was associated with 1.36-times higher odds for CVD (95% CI 1.04-1.77, p = 0.026). In the current study, calprotectin was the only inflammatory parameter significantly associated with CVD. The strong association of circulating calprotectin with smoking, a well-known direct cause of vascular inflammation, and also with CVD, stresses the urge for further research to define its role as a biomarker in T2DM.

PMID:33138021 | DOI:10.3390/ijms21218075

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Determinants of Increased Serum Calprotectin in Patients with Type 2 Diabetes Mellitus - DocWire News

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A deep dive into diabetes in Arkansas | Wear the Gown – THV11.com KTHV

November 3rd, 2020 6:57 pm

With the help of Laura O'Hern, endocrinology physician assistant at CHI St. Vincent Little Rock, we are describing diabetes.

LITTLE ROCK, Ark. In order to fully understand today's gowns topic, we first have to visit a factory. Lets just say this is a factory that processes sugar, but it's a factory where all the workers don't show up and you show up with a truck load of sugar that needs to go into the factory.

It's going to be much harder for that factory that's already on short staff to process a lot at one time, Dr. OHern said.

With the help of Laura O'Hern, endocrinology physician assistant at CHI St. Vincent Little Rock, we have just described diabetes.

It inherently comes down to the body is unable to process sugar in the normal way, Dr. OHern said.

To show how widespread it is in Arkansas, Dr. OHern has another analogy.

If you're in a room right now with any more than two other people, then the chances are that one of you has diabetes or pre-diabetes, that's serious, she said. That's a large percentage of the population.

With diabetes you have to see your doctor regularly. It's a progressive disease that only gets worse over time.

Without a pandemic on board, diabetes is the leading cause of blindness, kidney failure, and lower limb amputation in the United States, Dr. OHern said.

That takes us back to our factory, where you can learn a valuable lesson.

You can control how much sugar you deliver to that defective factory at any time, she said.

CHI St. Vincent, like most clinics, are up and running and willing to help while observing pandemic protocols, and once you make a commitment to improve, you change your life's trajectory.

I had a patient who came to me at the beginning of the year to talk about their diet, Dr. OHern said. This patient was on over 300 units of insulin a day and multiple other diabetes meds plus had hypertension, high cholesterol, lots of problems.

Hopeless? No. A low-carb diet, exercise and monitoring with checkups and consultations, what had begun in January 2020 with expensive insulin and a bleak future had reached the magical point where he didn't need to worry about his factory.

At ten months later, this individual is now completely off of al insulin with a nearly normal Hemoglobin A1c and he achieved this with dietary control, Dr. OHern said. And the weight loss came with him getting his diet into line, so I was incredibly inspired by that story.

Note that he was not alone.

It's just so much better when we do it together as a community, she said.

One final word about the classic early symptoms of diabetes: A lower energy level, and dry mouth. If that has been bothering you, call your primary care physician or CHI St. Vincent for help.

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A deep dive into diabetes in Arkansas | Wear the Gown - THV11.com KTHV

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Insulclock, in search of five million euros to advance against diabetes – Born2Invest

November 3rd, 2020 6:57 pm

Insulclock is preparing to open its first financing round. The Spanish company, specialized in the treatment against diabetes, has started a financing round of $5.8 million (5 million), as explained by Suso Prez, responsible for research and marketing of the company.

The company seeks to attract the interest of national and international funds. The economic boost it receives will serve to complete the national marketing of its device and begin internationalization, continue the second phase of technological development and continue with the development of products to improve the quality of life of people with chronic diseases, according to Prez.

Insulclock is an integral system that helps to improve the quality of life of people with diabetes and reduces the costs associated with this pathology helping to improve and efficient management by healthcare teams, according to the companys head of research.

Read more details about the biotech company Insulclock and find the latest financial news with the Born2Invest mobile app.

Jos Luis Lpez, CEO and co-founder of Insulclock, with type 1 diabetes for more than 21 years, founded the company in 2014 to provide a solution to a real problem for patients with diabetes: the need for a complete and global system that improves self-management and adherence to treatment for users.

During all this time, Lopez and his team, which currently consists of more than twenty people, have developed a telemonitoring and telemedicine system. This ranges from the automation of insulin data for insulin-dependent patients and self-monitoring of patients on oral medication to the integration of all health data available on the market into the patients clinical history in public and private health systems.

The work team is distributed between Galicia, Basque Country and Madrid, being a 100% national capital company and with most of the partners working within it. Suso Prez assures that the majority of the capital is distributed among the founding team. For the Insulclock team, people with diabetes generate a lot of clinical information on a daily basis: glucose, physical activity, food intake and adherence to treatment, among other data. In this way, the need arises to put order, not only in the generation of clinical information for self-management of diabetes, but also in the integration of this information automatically into the clinical history of each patient, the company explains.

The Spanish company is thus opening its first round of financing, since until now it has been able to meet all the investment in research and development (R&D) through the contribution of the partners. Even so, the company has obtained aid from the European Commission through Horizon 2020. We want to continue contributing to national and international clinical research, as we have already done with different clinical trials in which we have participated on an international scale, Prez points out.

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(Featured image by stevepb via Pixabay)

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First published in PlantaDoce, a third-party contributor translated and adapted the article from the original. In case of discrepancy, the original will prevail.

Although we made reasonable efforts to provide accurate translations, some parts may be incorrect. Born2Invest assumes no responsibility for errors, omissions or ambiguities in the translations provided on this website. Any person or entity relying on translated content does so at their own risk. Born2Invest is not responsible for losses caused by such reliance on the accuracy or reliability of translated information. If you wish to report an error or inaccuracy in the translation, we encourage you to contact us.

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