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The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes – Nature.com

February 7th, 2025 2:50 am

The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes  Nature.com

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The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes - Nature.com

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Q&A: Diabetes care for the aging population in the digital age – Medical Xpress

February 7th, 2025 2:50 am

Q&A: Diabetes care for the aging population in the digital age  Medical Xpress

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Q&A: Diabetes care for the aging population in the digital age - Medical Xpress

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Nanoparticle Therapy has Potential to Reprogram the Immune System in Type 1 Diabetes – Managed Healthcare Executive

February 7th, 2025 2:50 am

Nanoparticle Therapy has Potential to Reprogram the Immune System in Type 1 Diabetes  Managed Healthcare Executive

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Nanoparticle Therapy has Potential to Reprogram the Immune System in Type 1 Diabetes - Managed Healthcare Executive

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Assessing type-2 diabetes risk based on the Indian diabetes risk score among adults aged 45 and above in India – Nature.com

February 7th, 2025 2:50 am

Assessing type-2 diabetes risk based on the Indian diabetes risk score among adults aged 45 and above in India  Nature.com

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Assessing type-2 diabetes risk based on the Indian diabetes risk score among adults aged 45 and above in India - Nature.com

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Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study – BMC Public Health

February 7th, 2025 2:50 am

Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study  BMC Public Health

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Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study - BMC Public Health

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Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes – Nature.com

February 7th, 2025 2:50 am

Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes  Nature.com

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Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes - Nature.com

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Sugary Drinks Fuel Millions of Diabetes and CVD Cases – Medscape

February 7th, 2025 2:50 am

Sugary Drinks Fuel Millions of Diabetes and CVD Cases  Medscape

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Sugary Drinks Fuel Millions of Diabetes and CVD Cases - Medscape

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1 in 5 UK adults estimated to have diabetes in new record high – Euronews

February 7th, 2025 2:50 am

1 in 5 UK adults estimated to have diabetes in new record high  Euronews

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New, increasingly widely used diabetes medication may have additional health benefits for older adults – Medical Xpress

February 7th, 2025 2:50 am

New, increasingly widely used diabetes medication may have additional health benefits for older adults  Medical Xpress

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New, increasingly widely used diabetes medication may have additional health benefits for older adults - Medical Xpress

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Patients using diabetes apps can miss critical alerts. Heres how to make sure youre getting them – Canon City Daily Record

February 7th, 2025 2:50 am

Patients using diabetes apps can miss critical alerts. Heres how to make sure youre getting them  Canon City Daily Record

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Patients using diabetes apps can miss critical alerts. Heres how to make sure youre getting them - Canon City Daily Record

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Does wearing a continuous glucose monitor help people without diabetes? We asked experts. – Popular Science

February 7th, 2025 2:50 am

Does wearing a continuous glucose monitor help people without diabetes? We asked experts.  Popular Science

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Diabetes and obesity drugs fuel Eli Lilly profit in the final quarter of 2024 – News-Press Now

February 7th, 2025 2:50 am

Diabetes and obesity drugs fuel Eli Lilly profit in the final quarter of 2024  News-Press Now

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What is prediabetes and what can you do to stop it? – The Independent

February 7th, 2025 2:50 am

What is prediabetes and what can you do to stop it?  The Independent

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Diabetes symptoms: 6 high blood sugar warning signs that show on hand and feet – India.com

February 7th, 2025 2:50 am

Diabetes symptoms: 6 high blood sugar warning signs that show on hand and feet  India.com

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Diabetes symptoms: 6 high blood sugar warning signs that show on hand and feet - India.com

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‘Fix Broken Food System!’ Government Urged as Study Says 1 in 5 Brits Affected by Diabetes – Men’s Health UK

February 7th, 2025 2:50 am

'Fix Broken Food System!' Government Urged as Study Says 1 in 5 Brits Affected by Diabetes  Men's Health UK

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'Fix Broken Food System!' Government Urged as Study Says 1 in 5 Brits Affected by Diabetes - Men's Health UK

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The #1 Habit for Better Heart Health If You Have Diabetes, According to Experts – EatingWell

February 7th, 2025 2:50 am

The #1 Habit for Better Heart Health If You Have Diabetes, According to Experts  EatingWell

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101 Guide to Regenerative Medicine Types | Applications, Challenges

February 7th, 2025 2:50 am

Have you ever wondered about the future of medicine where healing is not just about managing symptoms, but regenerating lost or damaged tissues? Imagine a world where human tissues could be regrown, organs regenerated, or chronic conditions reversed. This is the promise of regenerative medicine, a rapidly advancing field that is reshaping the landscape of healthcare.

Regenerative medicine is revolutionizing the way we think about healing, offering hope for patients with injuries, degenerative diseases, or conditions previously considered incurable. It involves harnessing the bodys natural healing abilities to repair, replace, or regenerate damaged tissues and organs. But what exactly are the different types of regenerative medicine, and how do they work?

In this comprehensive guide, we will explore the various types of regenerative medicine, their applications, and the scientific breakthroughs making them a reality.

Regenerative medicine encompasses a variety of technologies and strategies that aim to restore the structure and function of damaged tissues and organs. Broadly speaking, there are several types of regenerative medicine, each with its unique approach and potential applications. These can be categorized into three main groups:

Lets dive into each of these types to understand their mechanisms, applications, and future potential.

Stem cell therapy is often considered the cornerstone of regenerative medicine. Stem cells have the remarkable ability to develop into different types of cells in the body, making them incredibly valuable for regenerative applications.

Stem cells are unspecialized cells that have the potential to differentiate into specialized cells with specific functions. There are two main types of stem cells used in regenerative medicine:

Stem cell therapy is being used in a wide range of applications, including:

Despite the exciting possibilities, there are challenges to stem cell therapy, including immune rejection, ethical concerns, and the need for better control over stem cell differentiation.

However, ongoing research is addressing these issues, and stem cell therapy is expected to become more effective and widely available in the future.

Tissue engineering is another pillar of regenerative medicine. This approach involves using a combination of cells, biomaterials, and growth factors to create functional tissues and organs. The goal is to replicate the complex structures of natural tissues and replace damaged ones.

Tissue engineering involves three main components:

By combining these components, tissue engineers create structures that mimic the natural architecture of tissues such as skin, bone, and blood vessels.

Tissue engineering holds immense promise in the creation and repair of tissues and organs, including:

Although tissue engineering has made significant strides, there are still challenges in creating fully functional, complex tissues and organs. The need for better biomaterials, vascularization (blood supply), and long-term viability of engineered tissues is a major hurdle.

However, innovations in 3D printing, biomaterials, and gene editing hold great promise for overcoming these obstacles.

Gene therapy is an emerging field that involves the introduction or alteration of genetic material within a patients cells to treat or prevent diseases. In regenerative medicine, gene therapy is used to stimulate the regeneration of tissues or repair genetic defects that hinder tissue healing.

Gene therapy works by delivering specific genes into a patients cells to promote tissue repair or regeneration. This can be done using several methods:

The goal is to use gene therapy to either:

Gene therapy is being used to treat a variety of conditions, including:

While gene therapy holds immense potential, there are still several challenges, such as ensuring the safe and effective delivery of genes, avoiding immune responses, and addressing ethical concerns surrounding genetic manipulation.

Despite these hurdles, gene therapy is poised to become an essential tool in regenerative medicine, with the potential to treat a wide range of genetic and degenerative diseases.

Regenerative medicine is advancing at an unprecedented pace, and the future looks promising. As research continues to unlock the full potential of stem cells, tissue engineering, and gene therapy, we can expect to see:

Regenerative medicine is no longer a distant dream; it is a rapidly growing field that promises to revolutionize healthcare. Whether through stem cell therapy, tissue engineering, or gene therapy, the ability to regenerate damaged tissues and organs holds immense potential to change the lives of millions.

While challenges remain, the continuous progress in this area offers hope for curing diseases and repairing injuries that once seemed impossible. The future of regenerative medicine is bright, and its transformative impact on medicine, healthcare, and quality of life cannot be overstated.

References:

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101 Guide to Regenerative Medicine Types | Applications, Challenges

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Regenerative Medicine | What is it? | ASCPM

February 7th, 2025 2:50 am

Regenerative Medicine aims to leverage the bodys innate healing mechanisms to repair, replace, or regenerate tissues and organs with damage or disease. This approach utilizes a variety of techniques including tissue engineering, gene therapy, and biomaterials to trigger the bodys regenerative processes.

Unlike traditional symptomatic treatments, it targets the root cause of ailments affecting muscles, cartilage, tendons, and ligaments, thereby stimulating and accelerating the bodys natural healing abilities.

At ASCPM, board-certified physicians bring years of expertise in minimally invasive procedures, with a focus on regenerative therapies. Through regular training, the ASCPM team stays abreast of the most effective techniques in Regenerative Medicine, ensuring optimal healing outcomes for patients.

Regenerative Procedures:

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Regenerative medicine and advanced therapy | NIST

February 7th, 2025 2:50 am

What is regeneratvie medicine and advanced therapy?

Credit: AdobeStock

Regenerative medicine therapy, including cell therapy, gene therapy, and therapeutic tissue engineering, provides unprecedented potential to treat, modify, reverse, or cure previously intractable diseases, such as cancer and organ failures. This class of therapy has completely changed the paradigm and the trajectory for medical treatment. Broad clinical translation and patient access requires advances in manufacturing technologies and measurements to ensure the safety, quality, and consistency of the therapy and to reduce the cost.

NIST is committed to solving the measurement challenges of this fast-moving sector of the bioeconomy by providing underpinning measurement infrastructure and platform technologies, as well as standards to promote manufacturing innovation, improve supply chain resilience, and support characterization and testing to facilitate regulatory approval.

The NIST Regenerative Medicine program is working closely with the U.S. Food and Drug Administration'sCenter for Biologics Evaluation and Research(FDA/CBER) and the Standards Coordinating Body (SCB) as well as the broader industry to develop global manufacturing and measurement standards underpinned by a robust measurement infrastructure needed to advance product development and translation as directed by Sec. 3036 of the 21st Century Cures Act.

The NIST laboratory programs support this growing industry as well as the broader industry ecosystem by:

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Regenerative medicine and advanced therapy | NIST

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Therapeutic Reprogramming toward Regenerative Medicine

February 7th, 2025 2:50 am

Therapeutic reprogramming represents a transformative paradigm in regenerative medicine, developing new approaches in cell therapy, small molecule drugs, biologics, and gene therapy to address unmet medical challenges. This paradigm encompasses the precise modulation of cellular fate and function to either generate safe and functional cells ex vivo for cell-based therapies or to directly ...

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Therapeutic Reprogramming toward Regenerative Medicine

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