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Psoriatic Arthritis Treatment Market Competitive Landscape Analysis with Forecast by 2028 – 3rd Watch News

July 9th, 2020 10:45 pm

Global Psoriatic Arthritis Treatment Market: Overview

The demand within the global psoriatic arthritis treatment market has been rising on account of advancements in the field of healthcare and biosimilar analysis. The occurrence of psoriatic arthritis can place an extremely negative toll on the overall health of individuals. This is because psoriatic arthritis is more severe than any other form of arthritis. Under psoriatic arthritis, patients suffering from a skin condition called psoriases start to exhibit extreme symptoms of arthritis. This results in excessive pain, uneasiness, and discomfort for the sufferer, often necessitating emergency dosage of steroids. Hence, there is a dire need to ensure that psoriatic arthritis is controlled which in turn gives an impetus to the growth of the global market. The revenue scale of the global psoriatic arthritis treatment market shall improve alongside advancements in the field of geriatric care.

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There is no permanent treatment for psoriatic arthritis, and it can only be controlled with proper medication. The discomfort suffered by people affected with psoriatic arthritis is abysmal. Owing to the aforementioned factors, the global psoriatic arthritis treatment market is projected to attract the attention of the medical fraternity in the years to follow. The demand for psoriatic arthritis is projected to reach new heights in the years to follow.

The global psoriatic arthritis treatment market can be segmented on the basis of the following parameters: drug class, route of administration, and region. Based on drug class, the global psoriatic arthritis treatment market can be segmented into Disease-modifying Antirheumatic Drugs (DMARDs), Nonsteroidal Antiinflammatory Drugs (NSAIDs), and biologics. Based on route of administration, the global psoriatic arthritis treatment market can be segmented into orals, topical, and injectables.

Global Psoriatic Arthritis Treatment Market: Notable Developments

Several advancement in the competitive landscape have become a key characteristic of the global psoriatic arthritis treatment market in recent times.

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Global Psoriatic Arthritis Treatment Market: Growth Driver

The occurrence of psoriatic arthritis is preceded by the severity of psoriasis in individuals. Hence, the field of dermatology needs to be work in conjunction with other medical departments in order to treat and control psoriatic arthritis. Hence, the global psoriatic arthritis treatment market shall expand alongside advancements in the field of dermatology. Furthermore, the availability of over-the-counter drugs for treatment of psoriatic arthritis propelled demand within the global market.

The joints suffer severe pain during psoriatic arthritis treatment, and the patients need to be quick recourse treatments. In a lot of cases, psoriatic arthritis poses a risk of permanent damage of joints. For this reason, the demand for psoriatic arthritis treatment has been rising at a stellar pace.

Global Psoriatic Arthritis Treatment Market: Regional Outlook

On the basis of geography, the global psoriatic arthritis treatment market can be segmented into North America, Europe, Asia Pacific, the Middle East and Africa, and Asia Pacific. The psoriatic arthritis treatment market in North America is expanding alongside advancements in the field of regional healthcare.

The global psoriatic arthritis treatment market can be segmented as:

Route of Administration

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How AI Is Slowly, But Steadily, Affecting The Treatment Of Rheumatoid Arthritis. – AI Daily

July 9th, 2020 10:45 pm

A condition that has no cure. A condition that has very generic risk factors. And, a condition that could make your life living hell.

Rheumatoid Arthritis (RA), is a condition that causes a person's immune system to attack their body cells, leading to severe damage to bones and cartilage. Symptoms include joint pain, weakness and inflammation around joints. RA affects over 400,000 people in the UK and is an autoimmune disease. As mentioned, an overactive immune system leads to it, but the reason behind such activity is something we yet do not know.

RA has no cure so far. And so, the only way to treat it is by giving immunosuppressants (medicine that reduces the activity of the immune system) or physiotherapy to ease joint pain. However, AI has been introduced to the RA landscape and so far, there have been studies on how it could help detect signs of RA early on, so minimal damage is done.

A study in 2019 from an American medical journal, JAMA Network Open was conducted, with a cohort of 116 and 117 RA patients. These were across a university hospital and a safety-net hospital. The model aimed to predict disease activity for a patient the next time they visited an RA clinic. Though the way of measurement is quite complex, the way the model performed was measured by calculating the area underneath a receiver operating characteristic curve (AUROC). This is a graphical plot that shows how well a system can distinguish between two groups. The conclusion came out to be 0.91 (university hospital) and 0.74 (safety-net hospital). Though to us, these results may not seem as much, to the researchers they showed that forecasting RA is possible with AI if data and AI models can be shared across hospitals.

Another very important advancement in the RA field was accomplished by healthcare start-up Living With, at the University of Bath, alongside the Royal United Hospitals Bath NHS Foundation Trust (RUH). A flare-up in medical terms is where the symptoms for a disease get worse, and that's when the disease is most active. These flare-ups can be difficult to predict. Living With have developed a Flare Profiler using smartphone technology and thermal imaging to stop the long-term harm from RA. A side-goal for Living With, is for RA patients to not always see a consultant each time they want to know how their body is coping up. They could see a specialist nurse, who would just need to interpret the data coming from the profiler. The profiler comes in the form of an app and will use AI to recognise disease patterns and then provide different routes for treatment.

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Medical herbalist Nicola Parker explains the treatment for different types of arthritis – Clitheroe Advertiser

July 9th, 2020 10:45 pm

Last week I wrote about arthritis, the type that happens as we age and our joints become victim to the usual wear and tear that comes with use.

Following on from that, Id like to talk about some of the other types of arthritis that can affect us.

Rheumatoid arthritis is not caused by wear and tear, but rather our own immune system attacking the joints. Unlike osteoarthritis, rheumatoid arthritis is not something that comes to most of us as we age although if you do suffer with it, then your joints may become gradually worse over time.

The immune system is triggered into acting as though we are being attacked at the site of the joints, causing swelling, redness and inflammation. This inflammation can be quite aggressive and in some cases the swelling itself causes the joint to mis-align, becoming painful and deformed permanently.

A common area for this to happen is in the finger and wrist joints. The fingers can start to bend in ways that are abnormal, making every day tasks like opening jars difficult and painful.

If you have rheumatoid arthritis, then nutrients like glucosamine, MSM, collagen and chondroitin are not the remedies to turn to. While these nutrients are used to repair and protect joints over time, in rheumatoid arthritis, the most important method of protecting your joints is to manage the inflammation and keep it under control.

Herbs that manage inflammation are too numerous to list in a single article but there are a few that are very specific to joint pain. One of these is devils claw, a herb that I was taught in my early years of training is especially helpful for arthritis that has begun to warp the fingers.

Since people with RA (rheumatoid arthritis) can end up with their fingers bent and curled at the joint, I was taught to remember devils claw for hands that are curled like claws.

Not everyone with RA has joint damage to this extent and managing the condition can help to avoid serious or more permanent changes to the joints. Devils claw is an anti inflammatory herb which acts by blocking some of the chemical pathways that lead to inflammation.

By blocking these pathways, the inflammatory response of the immune system is reduced, leading to less pain and a longer life for joints that would otherwise be damaged.

Unlike other pain medicines, devils claw should be taken over a period of eight weeks before you assess how well it is or isnt working for you. Rather than a temporary action that gets to work immediately but fades after a few hours, the effect of devils claw is gradually built up. Once it is working the anti inflammatory effect should be consistent and it is safe to take long term.

In a trial over eight weeks, patients with various rheumatic conditions were given a dose of devils claw. Results concluded that pain was significantly reduced by up to 58 per cent, so even though it can take a while to get to work, it is worth sticking out that eight week period.

If you suspect that you have an arthritic condition, getting a clinical diagnosis from your GP is very important. Your doctor can provide a blood test if they suspect that your arthritis is rheumatoid. If you test positive, then treatment can be provided that is specific to your condition, making it more likely to be effective and lengthening the life of your joints.

In some cases, autoimmune medicines are offered to stop your body from attacking itself. A big concern, especially during current times, of people on immune suppressants is that they may not be as able to fight off colds, bugs and viruses as they otherwise would be.

In this instance, you can help yourself with herbs but it is important to avoid anything stimulating like echinacea which can work against your medicine.

Instead, take immune nutrients like zinc, vitamin C and vitamin D to support your body more gently through nourishment.

For more information on arthritis and ways to manage it naturally, contact Nicola at her clinic on 01524 413733.

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Rheumatoid Arthritis Stem Cell Therapy Market Trends, Outlook and Opportunity Analysis 2018 to 2028 – Cole of Duty

July 9th, 2020 10:45 pm

Global Rheumatoid Arthritis Stem Cell Therapy Market Growth Projection

The new report on the global Rheumatoid Arthritis Stem Cell Therapy market is an extensive study on the overall prospects of the Rheumatoid Arthritis Stem Cell Therapy market over the assessment period. Further, the report provides a thorough understanding of the key dynamics of the Rheumatoid Arthritis Stem Cell Therapy market including the current trends, opportunities, drivers, and restraints. The report introspects the micro and macro-economic factors that are expected to nurture the growth of the Rheumatoid Arthritis Stem Cell Therapy market in the upcoming years.

The report suggests that the global Rheumatoid Arthritis Stem Cell Therapy market is projected to reach a value of ~US$XX by the end of 2029 and grow at a CAGR of ~XX% through the forecast period (2019-2029). The key indicators such as the year-on-year (Y-o-Y) growth and CAGR growth of the Rheumatoid Arthritis Stem Cell Therapy market are discussed in detail in the presented report. This data is likely to provide readers an understanding of qualitative and quantitative growth prospects of the Rheumatoid Arthritis Stem Cell Therapy market over the considered assessment period.

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The report clarifies the following doubts related to the Rheumatoid Arthritis Stem Cell Therapy market:

Segmentation of the Rheumatoid Arthritis Stem Cell Therapy Market

Competitive landscape

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Vital Information Enclosed in the Report

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Pfizer may have a lot going on in immunology, but all its drugs could be beaten by rivals: analyst – FiercePharma

July 9th, 2020 10:45 pm

Pfizers immunology portfolio includes the JAK inhibitor Xeljanz and a pipeline of five mid- to late-stage experimental drugsa huge stable of assets that seems well-positioned to fuel strong growth over the next five years.

But one influential Wall Street firm took a deep dive into that immunology portfolio and found a troublesome undercurrent that made its analysts wonder just how much it will really contribute to Pfizers future growth.

Analysts at SVB Leerink warned clients in a note on Wednesday that our review of the competitive landscape suggests Pfizers compounds could be beaten on speed to market, or better clinical data, in nearly all indications.

One challenge is that Pfizer is heavily dependent on JAK inhibitors, SVB Leerink said. Xeljanz is approved to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Pfizers nearest-term prospect in its immunology portfolio is JAK inhibitor abrocitinib, which is in phase 3 trials to treat atopic dermatitis.

The SVB Leerink analysts expect abrocitinib to be bringing in $2 billion in sales by 2027. Another phase 3 JAK inhibitor, PF-06651600 for alopecia, should peak at $500 million a year, they added.

But abrocitinib will likely carry the Black Box warning that the FDA has slapped on the JAK class, which warns of a high risk of serious infections, cancer, blood clots and other issues. That warning should relegate the drug to [second-line] behind Regenerons Dupixent until physicians gain experience and confidence in the product.

RELATED: AbbVie's Rinvoq scores pivotal trial win in eczema. But do dermatologists trust JAK inhibitors?

Dupixent is far from the only rival drug that could pose challenges for Pfizer. AbbVies JAK inhibitor Rinvoq, approved to treat rheumatoid arthritis last year, could score a green light in atopic dermatitis before abrocitinib does, SVB Leerink analysts predicted. In this situation, abrocitinib would not offer as much safety as Dupixent, or the efficacy of Rinvoq, and we'd expect it to struggle to gain market share, they said.

Last month, AbbVie released clinical trial data showing that Rinvoq was better than placebo at producing a 75% drop in atopic dermatitis symptoms and clear or almost clear skin after 16 weeks. At the time, SVB Leerink predicted Rinvoq could become the standard of care for patients who dont do well on Dupixent.

Pfizer has produced some positive data of its own, though it hasnt yet been impressive enough to convince analysts that abrocitinib will shoot to the top of the competitive class of JAK inhibitors. Last October, Pfizer said the drug produced clear or almost clear skin in 43.8% of eczema patients participating in a phase 3 trial, versus 7.9% of those taking a placebo. More recently, Pfizer reported a statistically significant improvement in symptoms among teenagers in a phase 3 trial.

RELATED: Pfizer's JAK abrocitinib comes through in teen eczema test

Pfizer is also testing a TYK2 inhibitor in psoriasis, but its facing stiff competition there, too. Bristol Myers Squibb is working on a TYK2 inhibitor, BMS-986165. SVB Leerink analysts pointed out that BMS recently posted clinical trial data suggesting its drug could offer double the effectiveness of Otezla, the drug BMS had to sell to Amgen in order to consummate its Celgene takeover. Add to that the fact that Pfizer is roughly two years behind BMS, and its hard to imagine it could make much of a mark in TYK2 inhibition, SVB Leerink said.

All in all, the analysts are projecting that Pfizers immunology sales will be flat this year and next at about $4.3 billion. From there, sales could grow 5% to 10% a year, they saidbut only if the companys JAK inhibitors are successful.

Ultimately, though, Pfizer may not be well-positioned to grab a significant piece of a rapidly growing market. Global JAK inhibitor sales could grow from $2.7bn to $19.3bn with additional launches and indications, SVB Leerink predicted, but if it materializes, Pfizer might get only a small share.

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Arthritis and the Cold Season – Business Daily

July 9th, 2020 10:45 pm

Health & FitnessSaturday, July 4, 2020 15:03

By DR FREDRICK OTIENO

Many patients with rheumatic diseases especially those presenting witharthritisreport increasing pain and stiffness during cold seasons.

Tales abound of how some patients can actually predict the onset of rain or cold weather from these symptoms. Whether it is a knee acting up when a rainstorm is on the horizon or, worse yet, a full-fledged rheumatoidarthritisflare when a blizzard hits, many of those with rheumatic diseases swear the weather harms their conditions.

The precise mechanism for this observation is not clearly understood, but it is thought that changes in weather can cause expansion and contraction of tendons, muscles, bones, and scar tissues, resulting in pain in the tissues that are affected byarthritis.

Low temperatures may also increase the thickness of joint fluids, making them stiffer and perhaps more sensitive to pain during movement.

What causes autoimmune diseases?

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Before addressing what precautions people living with rheumatic diseases can take during the rainy season, it is important to first understand what causes the condition. Anything foreign or toxic to our body are collectively called anti- gens; mostly some form of proteins or carbohydrate.

The immune system identifies these antigens and produces antibodies to get rid of them. Our cells, which are also made up of proteins and carbohydrates, escape the action of these soldiers due to the presence of specific distinguishing features called self-antigens. The immune cells, during their development in the thymus and bone marrow, are exposed to these self-antigens and made tolerant to them.

In a healthy individual, these tolerant cells go on to mature and become cells of the immune system. The body destroys the intolerant ones.

Many times, due to discrepancies in this process of destruction, the autoreactive immune cells escape the surveillance and can cause autoimmune disorders. These discrepancies can be genetic in origin, there could be a mutation in the self-antigens, or excessive and uncontrolled inflammation can lead to an overactive immune system.

Systemic autoimmune disorders occur when the effect of the autoreactive cells are seen all over the body, in conditions like lupus, rheumatoidarthritis, multiple sclerosis, and ankylosing spondylitis.

Arthritisis a common manifestation of most rheumatic diseases and is usually a result of inflammation.

Typical presentation includes:

What precautions can people living with rheumatic diseases take during the cold season?Patients with rheumatic diseases should be on effective treatment that ensures adequate disease control and suppression of inflammation at all times.

Treatments cannot cure autoimmune diseases, but they can control the overactive immune response and bring down inflammation or at least reduce pain and inflammation. These treatments include; non-steroidal anti-inflammatory drugs (NSAIDS), steroids, immunosuppressive drugs, and newer agents called biologic drugs.

Keeping warm: Dressing warmly, avoiding contact with cold water, take a warm shower, use hand gloves, warm bedding, and eat warm foods and beverages to reduce some of the effects seen when there is a drop in ambient temperature.

Exercise regularly: Exercise is crucial for patients living witharthritis. It is known to ease pain, increase strength and flexibility, and boost energy. The tendency during cold weather is for many people to shy off exercises. Patients should however prioritise exercise as this can ease the pain experience.

Dr Otieno is the assistant professor and consultant physician and rheumatologist at Aga Khan University Hospital, Nairobi.

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5 FDA approval decisions to watch in the 3rd quarter – BioPharma Dive

July 9th, 2020 10:45 pm

The next few months could bring the first gene therapy for hemophilia, a new type of multiple myeloma drug and an additional treatment option for a devastating muscular condition.

The Food and Drug Administration is set to make decisions on approval of all three, as well as on a closely watched arthritis pill and the first oral drug for spinal muscular atrophy, between July and September.

A regulatory OK for Roctavian, BioMarin Pharmaceutical's experimental hemophilia A treatment, would be a particularly significant milestone the first gene therapy for one of the world's most well-known inherited diseases. Approvals for Roche's risdiplam, NS Pharma's viltolarsen, Gilead's filgotinib and GlaxoSmithKline's belantamab mafodotin would also be notable.

The list of experimental drugs slated for the FDA's review during the third quarter was originally longer, but the agency cleared three targeted cancer therapies months ahead of schedule. (Seattle Genetics' Tukysa, Novartis' Tabrecta and Eli Lilly's Retevmo were all approved in April and May.)

Even as it's moved quickly to approve new drugs, the FDA has acknowledged the strain resulting from the work the agency is doing to oversee COVID-19 vaccine and drug development. So far, new drug reviews haven't been heavily affected, but the FDA has warned they could be slowed.

The five experimental drugs are listed in order of the currently scheduled date by which the FDA has agreed to make a decision on approval.

Around a dozen drugmakers are developing multiple myeloma treatments that target a protein known as BCMA, which is found on nearly all malignant cells. GlaxoSmithKline looks to be in a position to get there first.

GSK's drug, called belantamab mafodotin, is an antibody-drug conjugate, designed to bind to the BCMA target and deliver a small chemotherapy payload to attack cancerous cells. The conjugate approach is employed by Seattle Genetics' Adcetris and Roche's Kadcyla for other types of blood cancer.

Behind belantamab mafodotin, however, several other BCMA-targeting therapies are nearing key milestones, including a CAR-T cell therapy from Bristol-Myers Squibb and Bluebird bio, as well as a bispecific antibody from Regeneron.

They would trail belantamab mafadotin if the GSK drug is approved by the FDA's target decision date sometime this month. But the rival therapies could potentially offer advantages in greater effectiveness or more manageable side effects. Notably, balantamab mafadotin is associated with an eye-related side effect called keratopathy.

The FDA's decision to approve Sarepta Therapeutics' Exondys 51 for Duchenne muscular dystrophy in 2016 was one of the most controversial in the agency's recent history. The drug, a type of genetic treatment known as "exon-skipping," was the first specifically cleared for patients with DMD.

Approval late last year of Sarepta's second drug Vyondys 53 for a different segment of DMD patients was nearly as dramatic, with the FDA reversing an initial rejection after the company appealed to more senior agency officials.

The FDA's review of a DMD treatment developed by NS Pharma, a little-known subsidiary of Japan's Nippon Shinyaku, promises to be less eventful.

NS' drug, called viltolarsen and designed to treat the same group of DMD patients as Vyondys 53, works similarly to both of Sarepta's drugs. Study results published in JAMA Neurology this past May suggest it might even work better than Vyondys 53, although comparing drugs across trials can be misleading.

Like Sarepta, however, NS is offering the FDA limited evidence to go on. The study supporting the drugmaker's application primarily tested whether viltolarsen increased the production of a key protein that's largely missing in children with DMD and, notably, lacked a placebo comparison.

Having cleared Exondys 51 and then Vyondys 53, however, the FDA seems to have signaled it will accept early data as compelling enough to merit approval. A decision is expected sometime in August.

For Gilead and partner drugmaker Galapagos, much is riding on filgotinib. The drug is at the center of a research collaboration between the two companies, first inked in 2015 and then expanded with a $5.1 billion pact last year.

Part of a class of drugs called JAK inhibitors, filgotinib is aimed first at rheumatoid arthritis, a chronic condition for which it will have much competition. Three other JAK inhibitors, Pfizer's Xeljanz, Eli Lilly's Olumiant and AbbVie's Rinvoq, are already approved for rheumatoid arthritis, which is also commonly treated with biologic drugs like Humira.

Some analysts on Wall Street see filgotinib as safer than its JAK-blocking rivals, but the FDA appears to be viewing the risk of blood clots as characteristic of the drug class.

Gilead and Galapagos still think filgotinib can stand out and are counting on an August approval from the FDA to prove it. Clearance for rheumatoid arthritis would be the first step in proving the drug's future for other inflammatory conditions, like Crohn's disease, uveitis and psoriatic arthritis.

An approval for BioMarin's Roctavian would be a significant moment for the still-emerging gene therapy field. The experimental hemophilia A treatment wouldn't be the first gene therapy to gain FDA clearance that milestone went to Luxturna for an inherited form of blindness but it would offer thousands of patients long-lasting control of a disruptive and damaging bleeding disorder.

Roctavian also typifies the substantial benefits gene therapy can offer. Studies showed the treatment largely eliminated bleeding episodes, enabling patients to drastically reduce how much they rely on expensive factor replacement therapy that aids blood clotting. Years later, patients who received the treatment are still largely free of both.

BioMarin has suggested a price for Roctavian as high as $3 million, arguing the drug's value is clear when factor replacement therapy can sometimes cost as much as $1 million per year for severe hemophilia patients.

The company recently detailed follow-up data up to four years post-treatment in patients who were enrolled in early clinical trials. While their levels of blood clotting activity appear to decline over time, they are all still producing the Factor VIII protein that's reduced or missing in patients with hemophilia.

Spinal muscular atrophy, or SMA, is an often-fatal neuromuscular condition that primarily affects infants and children. Until three and a half years ago, there was no treatment.

An approval for Roche and PTC Therapeutics' risdiplam, expected by August 24, would bring to market the third treatment for the disease and the first one taken orally, which may be more convenient for some patients.

The companies have played up risdiplam's advantages compared to Spinraza, the first SMA drug, as well as versus Novartis' gene therapy Zolgensma. Spinraza is administered via a spinal injection, while Zolgensma is infused intravenously for treating infants.

Roche and PTC sought to submit to the FDA study data covering a broad range of patients, from infants to adults and across various levels of disease severity. In doing so, however, they caused the agency to extend its approval review by three months in order to take into account results from a study in less severe adolescents and adults.

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Skin problems, arthritis, reduced libido Why the body needs zinc and how to get it – The Saxon

July 9th, 2020 10:45 pm

Scientists believe that about 17% of people worldwide dont get enough zinc. This mineral is, however, very important, in particular, with the help of the body formed more than 300 different enzymes.

Who said that a lot of people, about 17% of the population experience zinc deficiency. Among the reasons for this called reducing consumption of animal food, the spread of diarrhoeal disorders and disorders of the intestine, chronic stress.

Zinc performs a very important function when its lack can even cause the fertility this mineral is essential for ovulation, the production of viable sperm, as well as to child bearing and lactation. But this is not all of its functions. Mineral helps preserve collagen in the skin and connective tissues, regulates the production of androgens, which in many cases are the cause of acne and other skin problems, it is involved in the synthesis of leukocytes, thyroid hormones, helps the body regulate the stress response.

Symptoms of zinc deficiency can be diverse, among them we can name:

In the body, zinc is not stored, so it must be regularly supplied in the diet. The daily menu should include seafood, poultry, beef, cocoa, egg yolk, whole seeds of flax, pumpkin and sesame seeds, wheat germ, lentils, almonds, peas, dairy products.

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Reactive Arthritis Treatment Market to Expand at a Healthy CAGR of XX% Between and 2017 2027 Bulletin Line – Bulletin Line

July 9th, 2020 10:45 pm

The global Reactive Arthritis Treatment market gives detailed analysis about all the important aspects related to the market. The study on global Reactive Arthritis Treatment market, offers deep insights about the Reactive Arthritis Treatment market covering all the crucial aspects of the market. Moreover, the report provides historical information with future forecast over the forecast period. Various important factors such as market trends, revenue growth patterns market shares and demand and supply are included in almost all the market research report for every industry. Some of the important aspects analysed in the report includes market share, production, key regions, revenue rate as well as key players.

The study of various segments of the global market are also covered in the research report. In addition to that, for the forecast periods determination of factors like market size and the competitive landscape of the market is analysed in the report. Due to the increasing globalization and digitization, there are new trends coming to the market every day. The research report provides the in-depth analysis of all these trends.

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In addition, the Reactive Arthritis Treatment market report also provides the latest trends in the global Reactive Arthritis Treatment market with the help of primary as well as secondary research methodologies. Additionally, the research report on Reactive Arthritis Treatment market provides a broad analysis of the market which includes market overview, production, producers, dimensions, price, value, growth rate, income, deals, export, consumption, and sales revenue of the global Reactive Arthritis Treatment market. On the other hand, the Reactive Arthritis Treatment market report also studies the market status for the forecast period. However, this will help to increase the marketing opportunities across the world as well as major market providers.

Key Players

Some of the players in reactive arthritis treatment market includes F. Hoffmann-La Roche Ltd, Teva Pharmaceutical Industries Ltd., Pfizer, Inc., Novartis AG, Amgen Inc., Velcura Therapeutics, Inc., Bayer AG, Geri-Care Pharmaceuticals, Merck Sharp & Dohme Corp, UCB S.A., Johnson & Johnson Services, Inc, Bristol-Myers Squibb Company, and AbbVie Inc., among others.

The report covers exhaustive analysis on:

The regional analysis includes:

North America (U.S., Canada)

Latin America (Mexico. Brazil)

Western Europe (Germany, Italy, France, U.K, Spain, Nordic countries, Belgium, Netherlands, Luxembourg)

Eastern Europe (Poland, Russia)

Asia-Pacific (China, India, ASEAN, Australia & New Zealand)

Japan

The Middle East and Africa (GCC, S. Africa, N. Africa)

The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macroeconomic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.

Report Highlights:

Detailed overview of parent market

Changing market dynamics in the industry

In-depth market segmentation

Historical, current and projected market size in terms of volume and value

Recent industry trends and developments

Competitive landscape

Strategies of key players and products offered

Potential and niche segments, geographical regions exhibiting promising growth

A neutral perspective on market performance

Must-have information for market players to sustain and enhance their market footprint.

NOTE All statements of fact, opinion, or analysis expressed in reports are those of the respective analysts. They do not necessarily reflect formal positions or views of Future Market Insights.

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The Reactive Arthritis Treatment market report also provides helpful insights for every established and innovative players across the globe. Furthermore the Reactive Arthritis Treatment market report offers accurate analysis for the shifting competitive dynamics. This research report comprises a complete analysis of future growth in terms of the evaluation of the mentioned forecast period. The Reactive Arthritis Treatment market report offers a comprehensive study of the technological growth outlook over time to know the market growth rates. The Reactive Arthritis Treatment market report also includes progressive analysis of the huge number of different factors that are boosting or operating as well as regulating the Reactive Arthritis Treatment market growth.

A systematized methodology is used to make a Report on the Global Reactive Arthritis Treatment market. For the analysis of market on the terms of research strategies, these techniques are helpful. All the information about the Products, manufacturers, vendors, customers and much more is covered in research reports. Various important factors such as market trends, revenue growth patterns market shares and demand and supply are included in almost all the market research report for every industry. Adaptation of new ideas and accepting the latest trends are some the reasons for any markets growth. The Global Reactive Arthritis Treatment market research report gives the deep understanding about the regions where the market is impactful.

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Reactive Arthritis Treatment Market to Expand at a Healthy CAGR of XX% Between and 2017 2027 Bulletin Line - Bulletin Line

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Rheumatoid Arthritis Treatment Market Prognosticated For A Ravishing Growth By 2026 – Daily Research Chronicles

July 9th, 2020 10:45 pm

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Scope of Rheumatoid Arthritis Treatment Market:

The Rheumatoid Arthritis Treatment market was valued at XX Million US$ in 2019 and is projected to reach XX Million US$ by 2024, at a CAGR of XX% during the forecast period. In this study, 2019 has been considered as the base year and 2020 to 2024 as the forecast period to estimate the market size for Rheumatoid Arthritis Treatment.

Due to the pandemic, we have included a special section on the Impact of COVID 19 on the Rheumatoid Arthritis Treatment Market which would mention How the Covid-19 is Affecting the Rheumatoid Arthritis Treatment Industry, Market Trends and Potential Opportunities in the COVID-19 Landscape, Covid-19 Impact on Key Regions and Proposal for Rheumatoid Arthritis Treatment Players to fight Covid-19 Impact.

The report also focuses on global major leading industry players of Global Rheumatoid Arthritis Treatment market providing information such as company profiles, product picture and specification, price, capacity, cost, production, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis are also carried out. With tables and figures helping analyze worldwide Global Rheumatoid Arthritis Treatment market, this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market. In general, the research report is a compilation of key data with regards to the competitive landscape of this vertical and the multiple regions where the business has successfully established its position. The report provides detailed information regarding the major factors (drivers, restraints, opportunities, and challenges) influencing the growth of the Rheumatoid Arthritis Treatment market. The Rheumatoid Arthritis Treatment Market Report analyzes opportunities in the overall Rheumatoid Arthritis Treatment market for stakeholders by identifying the high growth segments.

The scope of the report is limited to the application of the type, and distribution channel. The regions considered in the scope of the report include North America Country (United States, Canada), South America, Asia Country (China, Japan, India, Korea), Europe Country (Germany, UK, France, Italy), Other Country (Middle East, Africa, GCC). This report presents the worldwide Rheumatoid Arthritis Treatment market size (value, production and consumption), splits the breakdown (data status 20152019 and forecast to 2024), by manufacturers, region, type and application.

Market segment by Type, the product can be split into:Product Type Segmentation: Epicel, IntegraIndustry Segmentation: Chemical, Cosmetic, Pharmaceutical

The Global Rheumatoid Arthritis Treatment Market report analyses the production of goods, supply, sales, and the current status of the market in a detailed manner. Furthermore, the report examines the production shares and market product sales, as well as the capacity, production capacity, trends in sales, cost analysis, and revenue generation. Several other factors such as import/export status, industrial statistics, demand and supply ratio, gross margin, and industry chain structure have also been studied in the Global Rheumatoid Arthritis Treatment Market report.

The report comprehends precise analytical information related to market forecasts for several upcoming years. The report also includes the particulars about the valuation of macro and microelements significant for the growth of already established Rheumatoid Arthritis Treatment Market contenders and emerging new companies. The report uses SWOT analysis for the growth assessment of the outstanding Rheumatoid Arthritis Treatment Market players. It also analyzes the most recent enhancements while estimating the expansion of the foremost Rheumatoid Arthritis Treatment Market players. Additionally, the key product category and segments along with sub-segments of the global Rheumatoid Arthritis Treatment Market are studied in the global Market research.

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Full in-depth analysis of the parent market Important changes in market dynamics Segmentation details of the market Former, on-going, and projected market analysis in terms of volume and value Assessment of niche industry developments Market share analysis Key strategies of major players Emerging segments and regional markets Testimonials to companies in order to fortify their foothold in the market.

Further, in the research report, the following points are included along with an in-depth study of each point:

* Production Analysis Production is analyzed with respect to different regions, types, and applications. Here, the price analysis of various Market key players is also covered.* Sales and Revenue Analysis Both, sales and revenue are studied for the different regions of the global market. Another major aspect, price, which plays an important part in the revenue generation is also assessed in this section for the various regions.* Supply and Consumption In continuation of sales, this section studies the supply and consumption of the Market. This part also sheds light on the gap between supply and consumption. Import and export figures are also given in this part.* Other analyses Apart from the information, trade and distribution analysis for the Market, contact information of major manufacturers, suppliers and key consumers are also given. Also, SWOT analysis for new projects and feasibility analysis for new investment are included.

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Veterinarians and beekeepers: An arranged marriage – American Veterinary Medical Association

July 9th, 2020 9:50 pm

Veterinarians are still working to gain the trust of beekeepers in the wake of a federal rule that went into effect in 2017 bringing veterinarians and beekeepers together.

Dr. Terry Ryan Kane, a bee veterinarian in Michigan and secretary for the Honey Bee Veterinary Consortium, said the bee community did not anticipate the rule, which restricts beekeepers from using certain antimicrobials in honeybees without a veterinary feed directive or prescription from a veterinarian.

Most livestock producers have a relationship with a veterinarian, Dr. Ryan Kane said. That was not true for the beekeeping community. We are establishing relationships now. ... Someday it will be routine for veterinarians to be involved in the bee industry, but we are not there yet.

Historically in the U.S., beekeepers and veterinarians have had very little interaction, and beekeepers were able to administer over-the-counter antimicrobials themselves.

Dr. Ryan Kane compared the current situation with how veterinarians became involved with fisheries nearly 40 years ago. She said, Back in the 80s, we went through this with fisheries, when aquaculture was starting to grab hold in the U.S.

Dr. Ryan Kane, a backyard beekeeper herself, knows some veterinarians who just happen to also be beekeepers for fun.

Beekeepers are broken into three categories: backyarders, who keep only a few hives; sideliners, who have between 50 and 100 hives; and commercial beekeepers, who operate with over 300 hives. Commercial beekeepers make up a small portion of the overall industry but control the largest portion of bee colonies in the U.S.

There were 2.67 million bee colonies in January 2019, according to data from the U.S. Department of Agriculture. The beekeeping industry is worth about $17 billion a year, according to the National Honey Board.

Dr. Tracy Farone, a veterinarian who is a professor of biology at Grove City College in Grove City, Pennsylvania, and a board member of the Honey Bee Veterinary Consortium, said veterinarians were brought into the beekeeping world because of the diseases bees face and the potential for antimicrobial resistance.

I understand why beekeepers want to do what theyve always been doing, but theyre facing more and more bee health problems. It would be good to get veterinarians on board. Dr. Farone said. We can contribute here. We can provide so much more than a prescription or VFD to the industry. If we can blend veterinary medical expertise within the beekeeping industry, its not just an arranged marriage, but a marriage where we can help each other.

Including bee health within veterinary colleges curriculums is on the rise now in the U.S. But veterinary education in France has included an entire rotation on beekeeping for decades.

Ive gauged veterinarian interest, developed and shared lectures on what veterinarians need to know, Dr. Farone said. Bees are our most important agricultural animals, in regards to the number of crops they pollinate and their economic contribution to the agricultural industry. Without bees, the whole thing falls apart, so why wouldnt we have veterinarians for bees?

Dr. Farone suggests veterinarians interested in expanding their practice into bee health take the time to learn about the beekeeping industry, consider getting involved in local bee clubs, and identify current clients who have backyard hives.

Dr. Ryan Kane, who serves on the AVMA Committee for Environmental Issues, said the COVID-19 pandemic has put a spotlight on how the natural world needs to be taken care of.

Veterinarians should be at the forefront of protecting the environment, she said. Its one health.

Like Dr. Farone, Dr. Ryan Kane noted that bees are a key crop pollinator.

This is a global security issue. There is a veterinary public health obligation to protect our food resources, food safety, and food security, Dr. Ryan Kane said. We take insects for granted. We smash them, were afraid of them. We have shirked our duties by not studying them and not taking care of them. They make our systems work.

Dr. Ryan Kane said veterinarians who have bee health experience are promoting the insects.

She recently co-edited the forthcoming book Honey Bee Medicine for the Veterinary Practitioner with Dr. Cynthia M. Faux, a professor of veterinary science at the University of Arizona College of Veterinary Medicine. The book is a collaboration among veterinarians, entomologists, toxicologists, and a pharmacologist. It is set to be released in 2021.

Dr. Ryan Kane doesnt expect it will take long for veterinarians to be included in the beekeeping community.

It wont take many years to get us up to speed, to where the beekeeping community trusts our knowledge, but now we should learn from the beekeepers. There is so much information out there, she said.

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Terri the tortoise makes a turnaround – WSU News

July 9th, 2020 9:50 pm

Devin Schell, an animal technician at Washington State Universitys Veterinary Teaching Hospital, holds Terri, a 20-pound African spur-thighed tortoise. The tortoise was found on the side of the road and is believed to have been struck by a car.

By Josh Babcock, College of Veterinary Medicine

A tortoise believed to be run over by a vehicle could live another 90years thanks to the care of Washington State University veterinarians.

The unnamed tortoise, now known as Terri, was found on the side of a road in Benton City, Wash., back in March.

Her shell was smashed, there was a section of exposed spinal cord, and she was in shock when she was found. Miraculously, she was still able to move all four limbs.

Honestly, I didnt think she was going to make it, but I wanted to take her to the place where she would get the best care, Kyley Ackerson said.

Within minutes, Ackerson, with her fianc David Cotton behind the wheel, decided to make the one-hundred- and fifty-three-mile drive to WSUs Veterinary Teaching Hospital.

There, WSUs exotics team, with veterinarian Marcie Logsdon on the case, spent nearly three months tending to Terri.

We were hopeful. We thought she had a reasonable chance because she is an African spur-thighed tortoise and tortoises can heal some amazing things, Logsdon said.This one was a fighter.

The roughly 20-pound tortoise nearly succumbed to her wounds the first night.

If we wouldnt have taken her to WSU, she would have died that night, Ackerson said.

After a few weeks at the hospital, Terri started to grow new bone over the crack in her shell.

However, she was still slow and appeared ill.

As her stay at the hospital continued, veterinarians found Terri was not defecating. An x-ray revealed the tortoise had eaten over 70 rocks before she came to the hospital. The rocks ranged from quarter-sized stones to pea gravel.

Many enemas, fluids and weeks later, Terri was able to pass the rocks.

Logsdon said if not for the rocks, the tortoise would have been able to leave the hospital much sooner.

The only thing more shocking than the rocks to the exotics veterinarian the couples generosity.

They only knew this tortoise for five minutes and they drove all the way to Pullman and footed the entire bill, she said.

Ackerson said she raised more than $1,000 of that bill through a fundraiser on Facebook.

Friends, family, strangers I dont even know. They heard her story and now, here we are, Ackerson said. I am an animal person and I hope someone would do the same for me if I was in that situation.

Ten-year-old Terri is still bouncing back and strengthening her back legs for what could be the next 90 or more years of her life. She needs it too. Tortoises like Terri grow to an average of 70 to 100 pounds but can grow as large as 200 pounds.

Back in Benton City, Terri is getting spoiled with carrots, geraniums, hay and lettuce.

Reptiles dont show emotion, but I like to think shes happy, Ackerson said.

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Terri the tortoise makes a turnaround - WSU News

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Here’s why judicial use of antibiotics matters – Beef Magazine

July 9th, 2020 9:49 pm

Twenty years ago or so, antibiotic resistance wasnt on the radar for most cow-calf producers. If a calf got sick, you gave it a shot and it generally got better.

That began to change about 10 years ago, says Amelia Woolums, a veterinarian and professor of pathobiology and population medicine in the College of Veterinary Medicine at Mississippi State University. Around 2011, we started to see bacteria classically associated with BRD (bovine respiratory disease) being found with multiple resistance genes.

That was in lung samples from cattle that died from BRD. What about incoming cattle? Are the bacteria in those cattle carrying antibiotic-resistant genes?

READ: Preserving antibiotics for all

So she and others did a small in-house trial on 50 newly arrived high-risk calves. The calves all got an antibiotic on arrival and were nasally swabbed to see if any had highly resistant Mannheimia bacteria. On arrival, one calf tested positive. Fourteen days later, 88% had multidrug resistant Mannheimia on their nasal swab, she says.

That alone raised plenty of eyebrows. Then there was this: By day 14, all of the Mannheimias were also resistant to Baytril and we hadnt even given the cattle Baytril.

Without getting into the private lives of bacteria, the basic thing at work is that they can swap chunks of DNA. As that happens, genes that create resistance to antibiotics can spread. Even more fascinating as well as alarming is that the bacteria dont have to be closely related for that to happen.

READ: The last over-the-counter antibiotics?

None of this is breaking news any longer. Antibiotic-resistant bacteria has been a concern in both human and veterinary medicine for some time now.

It still is. Thats where you come in.

Weaning time approaches, and for some in drought areas, it may come sooner rather than later. As we plan for that annual ritual, now is a good time to revisit why the judicial use of antibiotics is so important.

READ: How to respond to consumer concerns over antibiotic use

Even more, its time to revisit why a herd health program that includes vaccinations is important. You know, people have been able to use antibiotics to cover up bad management and I feel like we cant rely on that any more, Woolums says. Weve got to go back to good management, really good cattle care. And then, when you need to use an antibiotic, try to pick the right one.

Thats because different antibiotics work best on different bacteria. So that means working with a veterinarian to use the right product appropriately.

Whats more, it means managing your cattle so they dont get sick in the first place. I think we need a renaissance of good husbandry, she says. Then, if we are a little more careful with how we use antibiotics, maybe theyll still be functional when we need them.

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Bats and COVID – Penn: Office of University Communications

July 9th, 2020 9:49 pm

COVID-19 is a zoonotic disease. For the 200+ bats currently in wildlife rehabilitation facilities across Pennsylvania, this presents a threat. Eman Anis, a microbiologistwith Penn Vets New Bolton Center, is leading a study to test for the presence of SARS-CoV-2 in North American bats, work being done with associate professors Lisa Murphy and Julie Ellis and Pennsylvania Game Commission biologist Greg Turner.

Because the School of Veterinary Medicine and the Pennsylvania Game Commission began collaborating in 2019 on the Pennsylvania Wildlife Futures Program to address wildlife health problems, they were able to shift quickly to COVID-19 research. Now, the team is developing a rapid diagnostic test using bat guano sent from local wildlife rehabilitation centers.

The researchers goal is to verify that bats held over the winter in rehab facilities will not transmit disease. When you do these tests, youre trying to ask questions, says Murphy. Can bats harbor it? Do bats in Pennsylvania harbor it?

Testing the guano of North American bats for COVID-19 ties into Penn Vets OneHealthfocus, which recognizes that human, animal, and environmentalhealthare interrelated and that an adverse event in anyoneof these areas may also adversely impact the others, Murphy says. With disease, humans, animals, and the environment can all play key roles in transmitting and maintaining harmful pathogens. Identifying the role that each plays can be the first step in understanding how to stop or prevent further harm, she says.

There is no evidence that North American bat populations currently harbor COVID-19 or other beta-coronaviruses like MERS and SARS, but there is a possibility that humans could transmit disease to bats, Anis says. This would present a public health risk and is one of the impacts her study will mitigate. We dont want have another reservoir where they can transfer it back to humans, she says.

COVID-19 has the potential to weaken the already precarious health of bat populations, says Turner. Bats have been his main focus for 16 years as populations have declined due to habitat loss and white-nose syndrome, a fungus originating in Europe that thrives in the cold, humid caves and mines that bats use for hibernation.

Pennsylvania is home to nine species recognized as resident breeding bats, according to the Game Commission. As bats are able to be a reservoir for most coronavirus strains, they are likely to contract COVID-19 if exposed, Turner says. While the animals are generally able to survive a dormant coronavirus, many North American bats are already stressed due to white-nose syndrome. This presents the risk that the virus would become active and cause an additive mortality factor on top of white-nose syndrome, which has decimated many bat species.

The Indiana bat is currently the only mammal on the federal list of endangered species in Pennsylvania. Were turning the tide, seeing stabilization and maybe even a recovery, Turner says. To have something come in now could be catastrophic to these species. What would happen if the bat was immunocompromised from white-nose fungus, would COVID-19 be an additive affect?

While bats are often vilified in popular culture, Turner says they provide numerous services we would miss if they were gone, he says. All of the bat species in Pennsylvania and the northeastern part of North America are insectivorous, so theyre eating nothing but insects. Each female little brown bat can consume 4,500 mosquito-sized insects per night. Bats consume an estimated 900,000 to 1 million insects per bat per year, says Turner, saving Pennsylvania farmers alone an estimated $3 million per year in crop damage and thus reducing the cost of production and the amount of pesticides used.

By eating insects, bats also prevent the spread of mosquito-borne diseases such as heartworm, encephalitis, West Nile virus, and potentially Zika virus, Turner says. We also have anecdotal evidence of people in wetland areas that were constantly battling mosquitos until they put up a bat box and had a colony of bats, he adds.

Bats are important to agriculture and to the ecosystems they live in, and theyre already under a considerable amount of pressure, Murphy says.

The New Bolton Center team began work on this project at the end of April, and Anis says the team is very confident that well be able to complete and validate the test and have it up and running soon. Our first goal is to help the rehab populations to release their overwintered bats, and we hope to expand beyond that.

The lab, which generally tests diagnostic samples, began guano testing during the pandemic. The team practice all the needed biosafety and biosecurity measures and follow all of the CDC guidelines, says Anis. Its a big challenge she says to work with this new normal and being isolated. Having a purpose has helped.

While the current study is targeted to a very specific population and need, it has larger implications, says Murphy. Why does this matter now? We have an immediate need, she says. Most wildlife rehabilitation facilities are staffed with volunteers and funded via donations. During the pandemic, most are operating with a skeleton crew and limited financial resources, continuing to feed and care for overwintered bats that are ready to be released into the wild. To the specific populations of bats in Pennsylvania and people who are caring for them, it really does matter, it matters now, and we have no data to inform their decisions, Murphy says. Were going to address a very specific need, but, in terms of where it can go from there, the ramifications and the benefits, this is only the first step, Murphy says.

In terms of thinking about what animal species may be susceptible to this virus, it doesnt just stop with bats, she says, citing evidence that weasels and ferrets are able to contract COVID-19, as can other animals. This disease is going to be with us, and is going to be a question and a concern for human and animal health for quite some time, she says.

Eman Anis is an assistant professor in pathobiology at the University of Pennsylvania School of Veterinary Medicine.

Julie Ellis is an adjunct associate professor in pathobiology at the University of Pennsylvania School of Veterinary Medicine.

Lisa Murphy is an associate professor of toxicology and director of the Pennsylvania Animal Diagnostic Laboratory System-New Bolton Center at the University of Pennsylvania School of Veterinary Medicine.

Greg Turner is a wildlife biologist with the Pennsylvania Game Commissions Bureau of Wildlife Management.

This study was made possible with support from the National Wildlife Health Center in Madison, Wisconsin.

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Longtime Niagara vet went ‘above and beyond’ for clients, community – NiagaraFallsReview.ca

July 9th, 2020 9:49 pm

Dr. Ron Mergl will be remembered for his infectious smile, ability to make people feel at ease, tireless work ethic, and giving back to the community.

He always went above and beyond for everybody that he met, said his wife, Dr. June Mergl.

He bent over backwards for all his clients. He often gave them his cell number and we always got a lot of calls and he would go in to meet them, if possible.

Mergl, who was a longtime owner of Niagara Falls Animal Medical Centre and Virgil Animal Hospital with his wife, died Saturday from glioblastoma multiforme, an aggressive brain tumour.

He was 61.

In a tribute posted to Niagara Falls Animal Medical Centres and Virgil Animal Hospitals Facebook pages Monday, June said her husband touched the lives of many individuals, both human and animal, and that his loss will leave a space that can never be filled.

His compassion and caring for all animals, large and small, and their owners for over 31 years at Niagara Falls Animal Medical Centre, and for over 35 years as a veterinarian in the Niagara region, will remain a cornerstone and tribute to him for many years to come.

She said her husband, who was born in Welland and grew up in Pelham, was more than a veterinarian. He was also a Christian, a philanthropist and a family man.

He contributed to, and participated in, so many foundations, boards, charity events, volunteer clubs and charities, that we have lost count.

Mergls volunteer ethic was ingrained in him.

He always believed you have to give back to the community thats given you so much.

June said her husband was an active participant along with his family at St. Andrews United Church for more than 25 years.

His pride and joy in the volunteer world, she said, was Rotary Club of Niagara Falls, where he was a past president and a multiple Paul Harris Fellow.

He was extremely generous with his time and his money to a fault and could not say no to any organization or extended family member that needed financial help.

Along with June, Mergl participated twice in Rotary International National Immunization Days against polio in India and Benin, Africa, spending a month at a time and using their own money to do so.

He also travelled to Malawi, in Africa, for Veterinarians Without Borders to vaccinate hyenas and dogs against rabies, which was killing the local children, and, with the help of Rotary International, started a lifesaving program of rabies vaccination in Uganda, that also saved many childrens lives.

June said although Mergl already had a bachelor of science and a doctor of veterinary medicine, he went back to school at Brock Univwersity, and received his masters of science in infectious and zoonotic diseases in 2010. He is listed as a co-author on several published articles as a result.

At one time, Mergl wrote a column for the Niagara Falls Review and, about four years ago, was honoured with an award of merit by the Ontario Veterinary Medical Association for all the work he had done in veterinary medicine and outside of his profession.

He was always attending veterinary conferences across the world to stay up to date in the latest advances in veterinary medicine, and to continue his high-quality level of care to his beloved patients and their wonderful clients.

June said her husband was also known for always being on the go.

Never miss the latest news from the Niagara Falls Review. Sign up for our email newsletters to get the day's top stories, your favourite columnists, and much more in your inbox.

He was busy with everything. He was full of ideas and projects and always planning vacations and fun things to do with his entire family.

June, who has been a veterinarian for 35 years in Niagara, said she will continue to run both the Niagara Falls and Virgil clinics for the time being.

She said people who want to remember her husband can donate to the research section of the Brain Tumour Foundation of Canada, Rotary Club of Niagara Falls and Veterinarians Without Borders.

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Certain feed additives may be effective tools against African Swine Fever – FeedNavigator.com

July 9th, 2020 9:49 pm

ASF has been spreading rapidly, threatening pork production and human food security worldwide.

The study from the K-State research team, headed by Megan Niederwerder, assistant professor of diagnostic medicine and pathobiology in the College of Veterinary Medicine, was published in the journal Transboundary and Emerging Diseases.

The team said the paper provides the first evidence that feed additives may be effective tools against the virus, that chemical feed additives may potentially serve as mitigants for reducing the risk of ASFV introduction and transmission through feed.

"Over the last two years, ASF is estimated to be responsible for the death of at least 25% of the world's pig population due to the emergence of the virus within China and subsequent spread to over 10 other Asian countries," Niederwerder said.

"In 2019, we published the first report of African swine fever virus, or ASFV, transmission through the natural consumption of plant-based feed. Our subsequent work has focused on mitigation of ASFV in feed through the use of chemical feed additives and heat treatment, she added.

Niederwerder and her team examined two different classes of liquid feed additives, including a medium-chain fatty acid-based additive and a formaldehyde-based additive, for efficacy against ASF virus in cell culture and in feed ingredients. In general, the scientists observed that both chemical additives demonstrated evidence of reducing the virus infectivity, with data supporting dose-dependent efficacy.

The study lead said there are currently no commercially available vaccines and no effective treatments that can be administered to pigs for ameliorating disease caused by the virus. Thus, control of ASF is focused on biosecurity measures to prevent the introduction of the virus into negative countries or negative farms and regions within a positive country.

The other method of containment would involve large-scale culling of infected or high-risk animals to contain the spread of the virus.

"Our new research reports novel data evaluating the efficacy of feed additives on inactivating ASFV in an in vitro cell culture model and a feed ingredient transoceanic shipment model," Niederwerder said. "This will provide valuable information to the swine industry with regards to mitigating the risk of potential routes for introduction and transmission of ASFV through feed and ingredients."

The K-State study was funded by a grant from the Swine Health Information Center and the State of Kansas National Bio and Agro-defense Facility Fund.

While she said the results of the study are promising, Niederwerder emphasized the need for a multifaceted approach to reducing the risk of ASF virus in feed, including sourcing ingredients from countries without the virus when possible, applying holding times to high-risk ingredients, and implementing consistent biosecurity protocols at the feed mill.

Source:Transboundary and Emerging Diseases

DOI:https://doi.org/10.1111/tbed.13699

Title:Mitigating the risk of African swine fever virus in feed with antiviral chemical additives

Authors:MC. Niederwerder, S. Dee, DG Diel, A MM. Stoian LA Constance, M Olcha, V. Petrovan, G. Patterson, AG CinoOzuna, R RR Rowland

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What the last living stars of Willy Wonka are up to now – Nicki Swift

July 9th, 2020 9:49 pm

Mike Teavee, played by Paris Themmen, was a bit younger and much rowdier than his other contest-winning peers. The 11-year-old cowboy-loving tween bounced around everyone else until he was "accidentally" trapped in a TV in the TV room of the factory and somehow stretched out to 10 feet tall (completely the Oompa Loompas' fault!).

After his charismatic role in Willy Wonka, Themmen had a brief career on Broadway as a teen in the late '60s and later became a theatre major at New York University. According to an archived version of his official website, he wanted to travel internationally following his graduation.

"I founded 'Access International,' a travel service sending backpackers standby on charter flights to Europe," he wrote. "During this time I visited 36 countries on 6 continents, (I'm up to 40 now!) everything from the Jungles of the Amazon to the Sahara Desert. You name it, I've been there."

His career path took multiple different paths, including real estate, film production, "a stint in Walt Disney Imagineering," retail, and more "entrepreneurial ventures." He honestly added, "As you can tell from my past, there is no telling what I may do next. (Direct?) In any case, I have lived a full and eminently satisfying life."

Themmen added a sentiment that all the living Willy Wonkaactors can likely relate to: "There is life after art."

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Glasgow University Vet school gifted 1m – The Southern Reporter

July 9th, 2020 9:49 pm

Mr Cheng has paid tribute to Professor Ian McIntyre with his donation.

Mr Tong Fatt Cheng served in the state Veterinary service in Singapore and then joined the diplomatic service in 1989 as Singapore Ambassador to Japan then to the Peoples Republic of China and as Ambassador-at-Large until his retirement in 2004.

The generous gift by Mr Cheng, who graduated BVMS in 1957 from the University of Glasgow, will be used to establish the McIntyre International Research Fellowships which will foster international collaboration in research on farm animal diseases.

The Fellowships will provide funding for a British veterinary graduate to work overseas for two years and for an overseas veterinary graduate to come to the Glasgow Veterinary School for two years.

By establishing the McIntyre International Research Fellowships, Mr Cheng is paying tribute to Professor Ian McIntyre, the Universitys first Professor of Veterinary Medicine.

Professor McIntyre was an inspirational and innovative teacher, and a strong advocate for international collaboration in veterinary education and research. He was a leading member of the Glasgow team which developed the first antiparasitic vaccine for cattle (Dictol).

In his later career, Professor McIntyre was seconded to the University of East Africa In Nairobi and went on to make further contributions to veterinary medicine In Africa.

Mr Cheng said: I am delighted to commemorate Professor McIntyres name in perpetuity through the creation of these international fellowships.

Professor McIntyre was an inspiring teacher when I was a student at the University of Glasgow Veterinary School and I have always admired his achievements both in Glasgow and internationally.

Originally posted here:
Glasgow University Vet school gifted 1m - The Southern Reporter

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‘Positive sign’ as 133 new vets are registered by Veterinary Council of Ireland – Limerick Leader

July 9th, 2020 9:49 pm

The Veterinary Council of Ireland has says 133 new vets and 48 new veterinary nurses have been added to its register so far in 2020.

The statutory body, which is responsible for the regulation and management of the practice of veterinary medicine and veterinary nursing in the state, welcomes its new registrants and believes this influx of talent will benefit animal health and welfare.

The total current number of vets and veterinary nurses on the Veterinary Council register is2,938 and 1,019 respectively.

Four of the new vets and two of the new vet nurses on the register are from county Limerick.

The council predicst that increasing numbers of Irish veterinary students qualifying in universities abroad, as well as increasing numbers of foreign vets registering to practice in Ireland, will help to meet the growing demand for large animal vets in rural areas.

Of the 133 newly registered vets, 50 were awarded their Bachelor of Veterinary Medicine Degree from University College Dublin (UCD).

Twenty-five vets were awarded their qualification from the University of Veterinary Medicine in Budapest, 11 were awarded their qualification from the University of Life Sciences in Warsaw and eight were awarded their qualifications from various universities throughout the United Kingdom.

The remaining vets received their qualifications from other universities abroad.

Of the newly registered veterinary nurses, 35 received their veterinary nursing qualification from UCD, three received their qualification from Letterkenny Institute of Technology; three from Athlone Institute of Technology, two from Saint Johns College Cork, with the remaining five receiving their qualifications overseas.

Vets from throughout Europe are eligible to register with the Veterinary Council of Ireland through the Professional Qualifications Directive, which facilitates the free movement of veterinary practitioners within the EU through the mutual recognition of professional qualifications.

The high number of newly registered vets this year is a positive sign for the profession and shows growth in the veterinary industry," says Veterinary Council of IrelandCEO and registrarNiamh Muldoon.

"It is the councils hope that the influx of new vets will help to meet the demands and recruitment challenges experienced by some under-serviced rural areas, particularly relevant to large animal practices. In order to address the issue of vet shortages, the Veterinary Council is analysing data and plans to conduct further research to inform possible solutions to this issue, she added.

Original post:
'Positive sign' as 133 new vets are registered by Veterinary Council of Ireland - Limerick Leader

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Generational Equity Advises New Generation Genetics in its Sale to Swissgenetics International – Business Wire

July 9th, 2020 9:48 pm

DALLAS--(BUSINESS WIRE)--Generational Equity, a leading mergers and acquisitions advisor for privately held businesses, is pleased to announce the sale of its client, New Generation Genetics to Swissgenetics International. The acquisition closed July 1, 2020 and details were not disclosed.

New Generation Genetics (NGG), located in Fort Atkinson, Wisconsin, has a primary goal of providing its customers with the best Brown Swiss genetics in the industry. NGG focuses solely on Brown Swiss, giving them the advantage over their competitors. The Company has over 50 years of Brown Swiss A.I. experience combined. They currently offer top bulls for Milk, Type, Net Merit, Sire Conception Rate (SCR), Fat, Protein, and PPR Index. They currently sample only the top genomic bulls and continue to lead the breed by sampling 12 young bulls per year.

Swissgenetics International is located in Zollikofen, Switzerland. Successful milk and beef producers rely on sustainable breeding strategies and professional production methods. To achieve this, high-performance and healthy animals are needed. The genetics programs from Swissgenetics are aligned consistently to meet and exceed these requirements. Through the testing programs operated in partnership with breeders and breeding organizations, marketable and future-oriented genetics are developed at an international level. Beneficial breeding cooperation assumes mutual trust between genetics providers and breeders. This requires high levels of competence and transparency on both sides. Swissgenetics is a leader in this field.

Generational Equity Executive Managing Director of M&A Central Region, Michael Goss, and his team lead by Managing Director Mergers & Acquisitions, Stephen Dinehart, with support from Managing Director Mergers & Acquisition, Ryan Johnson, successfully closed the deal. Senior Managing Director Joe Van Voorhis established the initial relationship with NGG.

This is a great acquisition for the Brown Swiss producer family combining two of the major players in Brown Swiss Genetics, said Dinehart. It is a win for both the customers and employees of Swissgenetics and NGG.

About Generational Equity

Generational Equity, Generational Capital Markets (member FINRA/SIPC), Generational Wealth Advisors, Generational Consulting Group, and DealForce are part of the Generational Group, which is headquartered in Dallas and is one of the leading M&A advisory firms in North America.

With over 250 professionals located throughout North America, the companies help business owners release the wealth of their business by providing growth consulting, merger, acquisition, and wealth management services. Their six-step approach features strategic and tactical growth consulting, exit planning education, business valuation, value enhancement strategies, M&A transactional services, and wealth management.

The M&A Advisor named the company the 2016, 2017, and 2018 Investment Banking Firm of the Year. For more information, visit https://www.genequityco.com/ or the Generational Equity press room.

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Generational Equity Advises New Generation Genetics in its Sale to Swissgenetics International - Business Wire

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