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5 things we know about the jobs of the future – World Economic Forum

January 25th, 2020 1:43 am

As the labour market rapidly changes, new, nearly real-time data and metrics give us better insight than ever before into what the jobs of the future will look like.

The kinds of jobs emerging in the global economy span a wide range of professions and skills, reflecting the opportunities for workers of all backgrounds and educational levels to take advantage of emerging jobs and the new economy. Identifying emerging jobs and the skills that they require provides valuable insights to inform training investments, and paves the way for a Reskilling Revolution, as individuals seek new skills to keep pace with change.

But for all of the opportunities that the new economy will bring, there are stark skills gaps and gender gaps that must be addressed. If we dont, they will continue to widen in the future.

Here are five things we can learn from this new data:

Not every emerging job requires hard tech skills, but every emerging job does require basic tech skills such as digital literacy, web development or graphic design. Three of the jobs in the World Economic Forum's Jobs of Tomorrow report cloud, engineering and data clusters, which are also among the fastest-growing overall require disruptive tech skills like artificial intelligence (AI), robotics, or cloud computing. Because technologies like AI are so pervasive, many roles in areas like sales and marketing will require a basic understanding of AI.

These disruptive tech skills are in high demand across the board. Blockchain, cloud computing, analytical reasoning and AI are among the most in-demand tech skills we see on LinkedIn.

While they arent growing as quickly as tech-dominated jobs, new sales, content production and HR roles are also emerging as a complement to the rapidly growing tech industry. Our research shows talent acquisition specialists, customer success specialists and social media assistants among the fastest growing professions all roles that rely on more diverse skills sets, especially soft skills.

Share of skills clusters by selected professional cluster

Image: World Economic Forum

Demand for soft skills is likely to continue to increase as automation becomes more widespread. Our latest Global Talent Trends Report shows that HR professionals are identifying the demand for soft skills as the most important trend globally. Skills like creativity, persuasion, and collaboration which all top our list of most in-demand soft skills are all virtually impossible to automate, which means if you have these skills youll be even more valuable to organizations in the future.

While the data reflects a diversity of opportunities for workers of all backgrounds and educational levels, further analysis shows a worrying imbalance in those obtaining the latest skills. In our ongoing research on gender with the World Economic Forum, we found that the largest gender gaps among emerging jobs are in roles that rely heavily on disruptive tech skills, with the share of women represented across cloud, engineering and data jobs below 30% (for cloud computing its as low as 12%). Its critical to close this gap because these disruptive tech skills will have an outsized impact on the direction of society and the economy.

While there is certainly room to improve gender parity by embracing greater diversity in hiring and more inclusive managerial practices, our data suggests that those gains, while important, will not be sufficient to achieve parity.

We have to think creatively about ways to fill these emerging skills and roles so that we prevent these gaps from intensifying in the future. Our research to understand these issues has uncovered some very achievable, scalable solutions.

Firstly, taking advantage of existing and adjacent talent can make a massive contribution to the rapid expansion of talent pipelines. Our research reveals that training and up-skilling near AI talent could double the pipeline of AI talent in Europe.

Opportunities by selected professional cluster and occupation, 2014-2019

Image: World Economic Forum

Taking a similar approach with the gender gap, weve found that sub-groups of disruptive tech skills where women have higher representation genetic engineering, data science, nanotechnology and human-computer interaction could expand the pipeline of talent for the broader set of tech roles that rely heavily on disruptive tech skills.

While both of these approaches can help us make meaningful progress, closing the skills and gender gaps depends on a lot more than just making sure talent has the right skills. Its a simple truth that who you know matters, so we also have to close the network gap the advantage some people have over others based purely on who they know.

Our research on the network gap shows that living in a high-income neighbourhood, going to a top school and working at a top company can lead to a 12x advantage in accessing opportunities. This means that two people with the exact same skills, but who were born into different neighbourhoods, may be worlds apart when it comes to the opportunities afforded them.

All of these new metrics and insights can help us pinpoint the skills and jobs of the future, but its going to take more than data to ensure that the Fourth Industrial Revolution is an equitable one. If we are going to make meaningful change, we need businesses and political leaders to re-evaluate the norms through which we shape policy, make hiring decisions and ultimately level the playing field for those who face barriers to opportunity.

As we convene at the Annual Meeting of the World Economic Forum in Davos, Im asking leaders to join us in making progress towards closing these gaps. It will create better, more innovative businesses, stronger economies and ultimately help create fairer societies.

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World Economic Forum articles may be republished in accordance with our Terms of Use.

Written by

Allen Blue, Co-Founder and Vice President, Product Management, LinkedIn

The views expressed in this article are those of the author alone and not the World Economic Forum.

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Re-engineering yeast to create biofuel appears possible, ‘but the effort involved is intimidating’ – Genetic Literacy Project

January 25th, 2020 1:43 am

A little while ago, we covered the idea ofusing photovoltaic materials to drive enzymatic reactionsin order to produce specific chemicals. The concept is being considered mostly because doing the same reaction in a cell is often horribly inefficient, because everything else in the cell is trying to regulate the enzymes, trying to use the products, trying to convert the byproducts into something toxic, or up to something even more annoying. But in many cases, these reactions rely on chemicals that are only made by cells, leaving some researchers to suspect it still might be easier to use living things in the end.

A new paper in Nature Catalysis may support or contradict this argument, depending on your perspective. In the end, the authors of the new paper re-engineer standard brewers yeast to produce molecules that can be used as fuel for internal combustion engines. The full catalog of changes they have to make is a bit mind-numbing, and most achieve a small, incremental increase in production. The end result is a large step forward toward biofuel production, but the effort involved is intimidating.

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An Interview with Ginkgo Bioworks Reshma Shetty On Co-Founding Synthetic Biologys First Unicorn – Forbes

January 25th, 2020 1:43 am

In co-founding Ginkgo Bioworks, Reshma Shetty has helped enable the entire synthetic biology ... [+] industry while inspiring a generation of new biological engineers. Heres what she told me about starting a biotech company.

Dr. Reshma Shetty is no stranger within the synthetic biology community. In 2008 she co-founded Ginkgo Bioworksa company youll definitely hear about if you havent alreadyalong with fellow MIT grad students Austin Che, Barry Canton, and Jason Kelly, and their graduate adviser, Professor Tom Knight. They started with a simple but revolutionary goal: help people design and build organisms. A decade later, Ginkgo achieved unicorn statusa private company valued at over $1 billionand it finds itself at the fore of the synthetic biology revolution with customers seeking to build organisms for use in fields as diverse as health, food, agriculture, cosmetics and materials.

Shetty has been through the whole journey and has been a major influence in the synthetic biology community. She had a major role in the first International Genetic Engineering Machine (iGEM) Competition with her co-founders. In 2008, she was named one of Eight People Inventing the Future by Forbes and, in 2011, one of the 100 Most Creative People in Business by Fast Company.

Shetty is an upbeat talker. If theres any stress or jadedness from navigating a company from birth to unicorn over a decade, it doesnt show. There is a sincere enthusiasm in her voice, especially when we discuss the science. When I caught up with her a few weeks back, one of things I wanted to know was: what do you do when you realize youre riding a biotech unicorn?

What was the moment when you realized that Ginkgo was going to be big?

It was when we closed our Series B financing. It was a $45 million round or roughly speaking, so that was more dollars dumped into our bank account at one instance than we ever had before.

My thought was, well pretty serious people withserious capital are choosing to take a bet on us.

This was confirmed for her in 2017 when Bayer chose to work with Ginkgo on engineering biologicals for agriculture, proving the intrinsic value of their platform and cementing Ginkgo as a platform company.

It proved three things at the time. One, that engineered microbes in the environment could be a thing, that [they] could be a product category. There are serious people taking serious bets that we're going to be able to release engineered microbes in the future. Two, that Ginkgos platform had value even in areas that we hadn't previously been in. Three, it proved to the world that Ginkgo was really a platform company, that we weren't simply going after a few products in the industrial biotech market.

It wasnt easy sailing for Gingko from the start though. Right after the company was founded, the global economy took a nosedive.

I think we incorporated in July of 2008 and, like literally, within the next month or two, the fiscal crisis hit, says Shetty.

In many ways this was not the ideal time to be starting a business and looking for investment, leading to creative thinking in getting the company going.

What did you learn in those early days that biotech companies could benefit from?

At the time everybody said that the way to start a biotech start-up is to go raise money immediately because you need some amount of money to be able to start a lab and get going. The thing I had to learn and realize was that no, actually, it is possible. If you're creative enough, savvy enough and patient enough, then you can in fact bootstrap even a biotech start-up.

Shetty stresses the importance of having the space to figure out their technology platform and business model and ask themselves how to take it forward. Having Knight and his wealth of experience on the team certainly helped.

Tom always said Oh, its a good idea to bootstrap in the early years regardless, based on his prior experience starting companies. But circumstances certainly reinforced that and I think that was really helpful that we spent the first few years bootstrapping the company.

Was it natural having your former advisor on the team?

Yeah, very natural. Tom, hes a pretty low-key guy, but he's also been very ahead of his time when it comes to thinking about the technology and technology trends. Early on it was great because Tom has started and run a company before and there were some obvious pitfalls that he could help us avoid and talk a bit about options.

And your other co-founders, what is it about them that makes them special?

I think probably for me the biggest thing is that we've now been working together for almost 20 years, says Shetty, referencing their time at MIT in the years before Ginkgo.

And even now, if I'm struggling with something or I'm trying to dig through how to solve a problem, I would want to talk to Tom, Barry, Austin, and Jason. I always come away having learned something or clarified my thinking or somehow changed how I was approaching a problem. To me, that is the real hallmark of excellence.

Despite all those shared experiences, they still learn from one another and solve problems together. Shetty considers her colleagues to be mentors too, saying shes benefitted from them as much as from her supervisors through the years.

Anybody can be a mentor, she says.

They are all engineers at heart, so the most exciting things for the Ginkgo team are around potentially world-changing technologies that can jump quickly from dream to reality.

What are the engineering challenges youre most excited about these days?

Bayer and Ginkgo, through our joint venture in Joyn, are going after nitrogen fixation. It has long been a dream of folks. Could we reduce fertilizer usage by using biological nitrogen fixation instead?

This project has been close to Shetty since her academic days, but therapeutics and Ginkgos collaboration with Synlogic, who develop bacteria as living medicines, has also piqued her interest.

There's all these areas of metabolism that lead to devastating diseases and the idea that you could engineer microbes to basically treat them is a cool idea!

Is there any particular problem youd like to solve through engineering biology?

How do you think about leveraging biology to make a positive impact on the environment? That's one I think has been on our wish list for a while.

Enabling the future of synthetic biology is a big part of how Ginkgo operates, even since the early days. The founders were involved in establishing iGEM and their platform is well suited to collaborative efforts.

How do you see Ginkgos role to give back and enable the next generation of synthetic biology?

I think one thing that has been a longstanding ask from folks in the community is how are we going to open up our cell programming platform to more people? Early on, that seemed crazy to even think about, she says, citing the skill set required to use and build it. I think we've come a long way since then so we can say actually maybe we get started thinking about opening up the platform to more folks.

Shetty says initial collaborations like Joyn, (Ginkgo spin-out) Motif, and Synlogic mean they can learn how to open their platform better. Relationships with accelerators like YCombinator and Petri are the next steps. They acknowledge that opening their platform will only benefit and accelerate biological engineering.

Our conversation then moves onto a more human element of running a company, a reminder that its never all about the science.

Do you have any mistakes or regrets in how youve done things?

The biggest regret I have is actually not thinking consciously about diversity and inclusion issues earlier in Ginkgos history. We started thinking about them seriously in about 2015 or so, when we were still relatively small, about 30 people. But we could have thought about diversity and inclusion even earlier.

Shetty reveals its easier to change the balance in a company when its just a handful of people.

Can we be doing better on diversity as a whole?

I would say that synthetic biology as a field has always been pretty good in that it thought about issues outside of just the science and engineering itself. I think the field always fosters that broader perspective. So I think it's been more natural and more normal to think about diversity and inclusion issues in the synthetic biology community as a result, says Shetty, We're by no means beyond reproach but there's more of a willingness to talk about these issues and really try to take proactive steps.

Do you have any advice for those starting a company?

The thing I like to tell people is that, if you're going to start a company, don't do it for the money. There are a lot of easier ways to make money in the world. Start a company because you think a company is really the best way to go tackle a problem that you're passionate about.

Any final thoughts?

I think that we've come a long way in terms of our ability to engineer biology, but we still have a long way to go. Fundamentally, biology is still not yet a predictable engineering discipline and its important to remember that. Because its still not yet predictable, we have to iterate through different designs and search for a functional design whenever we're trying to engineer a GMO. We have more work to yet do to bring down the cost of doing genetic engineering so that we can explore more and more of design space.

Follow me on twitter at @johncumbers and @synbiobeta. Subscribe to my weekly newsletters in synthetic biology and space settlement.

Thank you to David Kirk and Kevin Costa for additional research and reporting in this article. Im the founder of SynBioBeta, and some of the companies that I write about including Ginkgo Bioworks are sponsors of the SynBioBeta conference and weekly digest heres the full list of SynBioBeta sponsors.

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An Interview with Ginkgo Bioworks Reshma Shetty On Co-Founding Synthetic Biologys First Unicorn - Forbes

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Trump’s Presidency Brings Us Closer to Midnight on the Doomsday Clock – Truthout

January 25th, 2020 1:43 am

The legendary Bulletin of the Atomic Scientists (BAS), which tracks issues related to technology and global security, has issued a terrifying warning: We are less than two minutes to midnight on the Doomsday clock. Its very bad news, representing the most dangerous situation that humanity has ever faced.

What makes this moment so perilous? The scientists statement includes warnings over the cyber-weaponization of information, the spread of artificial intelligence (AI) in making military decisions, the destruction of treaties meant to limit the spread of nuclear weapons, the abandonment of global agreements to limit climate chaos, the spread of genetic engineering and synthetic biology technologies, and more. It does not account for the escalated likelihood of atomic reactor disasters, but based on at least one BAS publication, it should.

Since 1947, this prestigious band of elite scientists and global thinkers has been putting out a clock meant to time the peril of a global apocalypse. First issued at the dawn of the Cold War, it has mostly focused on the dangers of atomic warfare. Its countdown to Armageddon has been set as far away as 17 minutes from midnight, a hypothetical time of human extinction. That relatively optimistic assessment came in 1991, with the fall of the Soviet Union and the definitive end of the Cold War.

Get the latest news and thought-provoking analysis from Truthout.

In 2018, the BAS set it at two minutes, the closest to catastrophe it had ever been. They repeated that estimate in 2019. But this years announcement has taken us inside the two-minute warning with a hair-raising litany of likely lethal catastrophes set to occur within 100 theoretical seconds.

Donald Trump is mentioned only once by name, in conjunction with his decision to trash the Paris Accords on climate change and greenhouse gas emissions. The scientists urge whoever wins the 2020 election to reinstate the U.S. commitment limiting carbon and other climate-destroying emissions. The BAS also cites Brazilian dictator Jair Bolsonaro for his decision to allow the destruction of the Amazon, with huge impacts on climate.

The BAS strives to maintain a non-partisan image. But Trumps presence in the White House clearly hangs over any assessment of humankinds survivability. The specter of his finger on the nuclear, ecological and financial buttons for the next four years hangs over humankind like a pall but goes otherwise unmentioned in this Doomsday assessment.

Also unmentioned is the question of more than 450 atomic power reactors worldwide. A small but vocal outlier coterie has argued that nuclear energy combats global warming by emitting less carbon that coal burners. But the Bulletin recently enshrined a major assessment by the esteemed Dr. Robert Jay Lifton, warning that commercial reactors pose a serious threat to human survival on this planet.

Published in August 2019, The false promise of nuclear power in an age of climate change argues that the 450 atomic reactors now deteriorating worldwide pose an existential threat to our survival. Writing with Professor Naomi Oreskes, Lifton warns that atomic energy is expensive and poses grave dangers to our physical and psychological well-being. Citing costs of nuclear juice at $100 per megawatt-hour versus $50 for solar and $30-40 for onshore wind, the authors say that the industry suffers from a negative learning curve, driving nuke costs constantly higher while those for renewables head consistently down.

Citing the unsolved problem of radioactive waste management, the BAS article warns of the ongoing impacts of major disasters like Fukushima and Chernobyl (and potentially more to come), whose fallout kills humans and does untold damage to the global ecology. Lipton and Oreskes say we need to free ourselves from the false hope that a technology designed for ultimate destruction can lead to our salvation. They favor making renewable energies integral to the American way of life.

In addition to nuclear and climate issues, the 2020 Doomsday assessment emphasizes some relatively new concerns. In the last year, it says, many governments used cyber-enabled disinformation campaigns to sow distrust in institutions and among nations, undermining domestic and international efforts to foster peace and protect the planet.

By attacking both science and the fabric of international peace accords, some global leaders have created a situation that will, if unaddressed, lead to catastrophe, sooner rather than later.

That situation includes AI and hypersonic warfare, both escalating at a frenzied pace. Now used in ultra-fast attacks, AI is dangerously vulnerable to hacking and manipulation while making kill decisions without human supervision. In nuclear command and control systems, the BAS warns, research and experience have demonstrated the vulnerability of these systems to hacking and manipulation.

This is an absolutely terrifying brew. The spread of disinformation, the contempt for science and expert opinion, the undermining of global agreements on arms control, and climate change are all deadly. Add in the new world of AI and hyper-sonic warfare, then pile on autocrats like Trump and Bolsonaro, and finish with the certainty of more disasters from 450 crumbling, obsolete atomic reactors.

All in all, its small wonder the Bulletin has taken us past the two-minute warning. It will clearly take every ounce of our activist strength to save our species from the final whistle.

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Trump's Presidency Brings Us Closer to Midnight on the Doomsday Clock - Truthout

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Superbug treatment named for patient who inspired its discovery – STAT

January 25th, 2020 1:43 am

Even for the most elite of bacteria-killers, these superbugs were a challenge.

Theyd delayed Mallory Smith from getting a lung transplant, and when shed finally had the surgery, the bacteria quickly migrated into her new lungs. They shrugged off cocktail after cocktail of antibiotics. Finally, Smiths father proposed an unusual last resort: finding viruses that parasitize bacteria and injecting them into his daughter. But the experimental treatment came too late. Smith died on Nov. 15, 2017, a little over a month after shed turned 25.

Yet her bacterial infection lived on, passed from scientist to scientist, from freezer to freezer, traveling from Smiths hospital room in Pittsburgh, Pa., to a lab in Ann Arbor, Mich., eventually landing in a Petri dish in Jerusalem, some 6,000 miles away. Now, microbiologists at Israels Hebrew University have described a new virus thats especially good at combating Smiths superbug.

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Its a phage that kills the strain that killed Mallory, said Ronen Hazan, who led the team. This was the best one and we decided to name it after her.

It isnt the first bacteriophage as such bacteria-fighting viruses are known that can work against this sort of intractable infection. After all, there are trillions of phages out there, feasting on the bugs that fill our sewage and hunting for hosts in puddles after rain. Even if theyre extreme specialists, attacking only specific strains of a specific species of bacteria, theres usually more than one that infects a particular superbug. Smiths doctors had tried out a few that may have done the trick if injected earlier.

Yet the mere fact that researchers are looking for phages to try as therapies is a sign of how much has changed since and because of Smiths death. The hope is that next time theres a case like hers, a potentially lifesaving treatment will be ready sooner.

The recent surge of phage therapy enthusiasm is a revival of sorts. In the 1930s, you could get phage concoctions to treat everything from dysentery to urinary tract infections to outbreaks of the skin. But then, in the 1940s, penicillin hit the market, and antibiotics became the rage. Eastern European researchers continued to use phages as treatment, but such Soviet science was viewed with suspicion back in the United States.

It was only with the rise of antibiotic-resistant bacteria that Western interest in these viruses-as-treatments began to brew again. Even so, in 2017, many still considered the idea esoteric at best. That was part of the holdup for Smith. There was no established method for finding, purifying, and delivering the viruses her doctors hoped might save her life. When her father reached out to scientists who had a bit of experience with phage therapy, all they could do was send out a frantic flurry of emails and tweets.

Smiths story helped change that. Shed been born with cystic fibrosis, a genetic illness that fills the lungs with a particularly gluey sort of mucus. Not only does that make it hard to breathe it also acts as a cushy home for bacteria. When two friends whod met through swing dancing one a grad student, the other a tech consultant read about Smiths desperate attempt to find a virus that would beat back the bacteria within her, they created an online phage directory to help speed things up. Then, in 2018, the University of California, San Diego, established the first phage therapy center in the U.S.

Yet for a patient with Burkholderia cepacia the kind of bacterial infection that Smith had finding the right phage in time is hardly a shoo-in. Partially thats because its not the most common superbug infection, even among cystic fibrosis patients, so not all that many researchers are working on treating it with phage therapy. But its also because B. cepacia is an especially tricky type of bacteria to phage-hunt for. Some phages the ones that are easiest to use as therapies enter a superbug, replicate like crazy, and cause the host to explode. Others, though, simply integrate peaceably into the bacterial genome. And the phages discovered for B. cepacia often fall in the peaceful-coexistence camp. Plus, for other kinds of bacteria Pseudomonas, say, or Klebsiella a phage might be active against a large swathe of strains; for Burkholderia, Hazan explained, the viruses are choosier.

Thats where his lab comes in. The teams hope is to build up a library of B. cecpacia-killing phages that can be used in cocktails whenever a case like Smiths pops up. To do that, the scientists have collected all sorts of substances most people would rather not deal with. They take the used saliva, urine, and fecal samples from hospitals. Instead of discarding them, we take them and search for phages, Hazan explained. Were looking in water bodies, small lakes. After the rain, in puddles. Whenever a student goes on vacation we ask him, Bring some samples of soil or water or whatever!

They also regularly take wastewater from West Jerusalems sewage treatment plant, which is where the phage active against Smiths bacteria came from. Everybody complains about the smell, but we are finding gold in that sewage, Hazan added.

Three Hebrew University students Chani Rakov, Ortal Yerushalmy, and Leron Khalifa first isolated the phage in question this past December. When they put it into a Petri dish covered in the kind of bacteria that had been collected from Smiths lungs, it began to create clear spots where the superbug was dying off. The decision was unanimous that it should be named BCMallory1, for the initials of the bacteria its active against, and the name of the person who helped inspire the search.

When she heard the news, Smiths mother began to cry. To her, it meant that other families might not have to live through what she did. Its a very bittersweet feeling, said Diane Shader Smith. You know the suffering, and you dont want anyone to suffer, but also you think, Mallory could have lived.

Because bacteria often develop resistance to phages as well, many researchers think its best to deliver a cocktail of phages alongside antibiotics, and Hazan plans to keep searching. Hes also thinking about the possibility of genetically engineering some of the phages his team finds, to make them safer or more efficient bacteria-killers.

We dont want to have another Mallory Smith, said Steffanie Strathdee, co-director of the Center for Innovative Phage Applications and Therapeutics, at University of California, San Diego, and co-author of The Perfect Predator, a book about how she saved her husbands life through a similar phage hunt in 2016. Smiths case still haunts her, she said: I think about her every day. We came so close to saving her life.

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Superbug treatment named for patient who inspired its discovery - STAT

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You can send your tardigrades to space and back, but don’t eat one. Got that, boomer? – Real Change News

January 25th, 2020 1:43 am

With Trumps trial in the Senate going on, it feels like a good time to talk about random news items. I want to distract mystelf from President Trumps pending acquittal.

I spelled mystelf correctly. Mystelf is a legitimate word I made up yesterday to mean my stupid self.

The first news item that caught my eye was about scientists discovery that tardigrades arent as indestructible as weve been told. Tardigrades are those little microscopic animals also called water-bears who look kind of cute with pudgy feet and can survive all kinds of cold. They can survive a drought. Theyve even been subjected to the vacuum of space and lived and shown no ill effects.

But nobody until now, apparently, thought of cooking them. Well, they dont look yummy, Ill admit.

Still, youd think in all this time, someone would have wondered how well theyd do in the noonday sun on a Moroccan summer day. It turns out they cant take it.

Good news for me. The research shows that my stupid body temperature is just the right amount of heat to kill off any tardigrades that find their way deep inside me. It would only take a week or two. Excellent. I had wondered if a tardigrade infestation was possible. I can now relax, safe knowing they could only live skin-deep in me.

My favorite government agency is DARPA, the Defense Advanced Research Projects Agency. The agency solicits and supports research of all sorts, but usually theyre looking for a defense angle. The reason we can use the internet is because of a project of theirs back when the agency was called ARPA. What was then called the ARPA-net was thought a great system for communication that could function even during a nuclear attack. That was before Russian hackers, malware, denial of service attacks, etc.

Whenever youre bored and fed up with looking at cute cat videos, go to the DARPA website, click the Our Research link and browse all the projects they have going. It gets wild.

You may know some of them. Boston Dynamic Robots came out of one of their projects: robots that walk and run on all fours and can get back up when theyre down. DARPA has pushed a lot of Star Wars-ish projects like that.

Lately theres been a rash of projects involving genetic modification of plants and animals for defense purposes. One of them is called the APT project. APT stands for Advanced Plant Technologies. The goal of the project is to genetically engineer a variety of plants that can be used as sensors to detect chemical, biological, radiological, nuclear, and explosive (CBRNE) threats to protect deployed troops and the homeland. See why I like reading these things? Troops and the homeland. Sheer poetry.

Another one of these is the ELM project (yes, they all get acronyms like that its so precious): Engineered Living Materials. This week there was news about the engineering of a kind of living brick. Its a brick you can use like any brick: You can throw it at someones head or use it as a paperweight, but its ingredients include a kind of genetically modified bacteria. The bricks are alive.When you need more bricks, you can break them up and the pieces will grow new bricks. You do have to feed and water them. They eat sand and a certain kind of gelatin, and guzzle CO2. I want one for a pet. I will call her Cyan.

The final news item that caught my eye skirted dangerously close to the Senate trial. I almost looked away in horror when I saw it concerned John Roberts, the chief justice of the U.S. Supreme Court, who is now presiding over the trial. But it wasnt about that. It was about John Roberts dropping the phrase OK, Boomer in arguments in an age discrimination case before the court.

He was wondering whether saying OK, Boomer to a job applicant in an interview could be evidence for age discrimination later if the applicant gets turned down.

Im glad its getting unpopular to be a Baby Boomer. One of the things Ive hated all my life is there have always been too many of us. Every other generation gets assigned about 10 years. Boomers got 1945 to 1964 20 years. Thats not right. All you people born 1955 to 1964 (that includes John Roberts), I now proclaim you the After-Shock Generation.

Dr. Wes Browning is a one time math professor who has experienced homelessness several times. He supplied the art for the first cover of Real Change in November of 1994 and has been involved with the organization ever since. This is his weekly column,Adventures in Irony, a dry verbal romp of the absurd. He can be reached at drwes (at) realchangenews (dot) org

Read the fullJan. 22-28 issue.

2020Real Change. All rights reserved.Real Change is a non-profit organization advocating for economic, social and racial justice since 1994.Learn moreabout Real Change anddonate nowto support independent, award-winning journalism.

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You can send your tardigrades to space and back, but don't eat one. Got that, boomer? - Real Change News

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This Regenerative Building Material is Made From Sand and Bacteria – Discover Magazine

January 25th, 2020 1:43 am

(Inside Science) -- Castles made of sand could, with the help of bacteria, grow copies of themselves and become as strong as the cement that commonly holds bricks together, a new study suggests.

Such living materials could one day help people colonize Mars, scientists added.

After water, concrete is the most used material on Earth, at a rate of about 3 metric tons used per year for every person in the world. Cement, the primary component of concrete, is the oldest artificial construction material, dating back to the Roman Empire.

Cement and concrete have changed little as technology for more than a century. Now scientists are seeking inspiration from natural processes, such as the way colonies of coral polyps build reefs.

"We want to blur the boundaries between the natural world and the built environment, between what is nonliving and what is living, and create a material that displays both structural and biological functions," said materials scientist Wil Srubar, who heads the Living Materials Laboratory at the University of Colorado Boulder.

The researchers started with sand, gelatin and a kind of photosynthetic bacteria known asSynechococcusthat is widespread in ocean surface waters. The gelatin retained moisture and nutrients for the bacteria to proliferate and mineralize calcium carbonate in a way that is similar to how seashells form.

In experiments, the resulting material was roughly as strong as typical cement-based mortars.

"I have a small cube of the material on my desk that is 2 inches across that I can stand on," Srubar said.

The material not only is alive, but can reproduce. When researchers halve one of the bricks, the bacteria can help grow those halves into two complete bricks when supplied with extra sand and gelatin. Instead of manufacturing bricks one by one, the researchers showed they could grow up to eight bricks from one.

"Conventional manufacturing approaches make one widget at a time," Srubar said. "By using one brick to grow two bricks, and then four, and then so on, we can explore the idea of exponential manufacturing of building materials. Given that time is money, I think anyone involved in manufacturing would find speeding up manufacturing time very interesting."

Previous research used bacteria to repair cracks in concrete and oil and gas wells by mineralizing calcium carbonate. However, such work typically used microbes that fare very poorly in typical materials used like cement, which are highly acidic -- only 0.1 percent to 0.4 percent of such bacteria survived after 30 days. In contrast, in this new work, 9% to 14 percent of the bacteria remained viable after 30 days assuming at least 50 percent humidity was maintained.

One challenge the scientists face is that the material needs to get completely dried out to reach its maximum strength, but such drying stresses out the bacteria. To help keep the microbes alive, the researchers currently have to control the humidity surrounding the material.

"We're looking to create a desiccation-tolerant strain of bacteria so that we can get full structural capacity while also enhancing microbial viability in super-dry conditions," Srubar said.

All in all, "we're particularly excited about the possibilities of this material technology in austere environments with limited resources," Srubar said. "If you have microorganisms that can grow structural materials in remote places, that could help build everything from a military installation to human settlements on other planets."

Srubar said the current research acts as a proof of concept for the stronger compounds that could be made with the technique.

Ultimately the scientists envision using microbes that not only help build materials but impart structures with extra biological functions.

"You can imagine bacteria that provide materials with self-healing capabilities, or can sense and respond to toxins in the air, or can interact with the environment in other ways," Srubar said. "The sky's the limit with creativity."

"I find it exciting that this new work develops materials that are truly living, in that the microorganisms incorporated into their materials survived at very high rates over time periods of weeks," said Anne Meyer, a synthetic biologist at the University of Rochester in New York, who did not take part in this research. "Creating a truly living material allows the possibility of using genetic engineering techniques to add additional behaviors to the microbes living within the material. Could you incorporate a microbe that could respond to environmental cues to change the toughness or stiffness of the bacteria?"

She added that it might be possible to combine the new research with work from her lab that uses 3D printers to build shapes from bacteria.

The scientists detailedtheir findingsonline Jan. 15 in the journalMatter.

[This article originally appeared on Inside Science. Read the original here.]

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This Regenerative Building Material is Made From Sand and Bacteria - Discover Magazine

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Scientists Combine AI With Biology to Create Xenobots, the World’s First ‘Living Robots’ – EcoWatch

January 25th, 2020 1:43 am

A Trillion ToxicGallons

Oil and gas wells pump out nearly a trillion gallons of wastewater a year, Rolling Stone reported. That's literally a river of waste enough to replace all the water flowing from the Mississippi River into the Gulf of Mexico for more than two and a half days.

Much of that wastewater, often referred to by the industry as "brine," carries high levels, not of familiar table salt, but of corrosive salts found deep below the Earth's surface, as well as toxic compounds and carcinogens.

That water can also carry serious amounts of radioactive materials. The Rolling Stone report, labeled "sobering" by the Poynter Institute, described levels of radium as high as 28,500 picocuries per liter in brine from the Marcellus Shale, underlying Pennsylvania, Ohio, New York, and West Virginia, levels hundreds of times as much as the Nuclear Regulatory Commission would allow in industrial discharges from other industries.

The oil and gas industry's waste, however, isn't regulated like most other industry's wastes, slipping instead through loopholes carved out in the nation's cornerstone environmental laws, including exemptions for the industry in federal laws covering hazardous waste.

"If I had a beaker of that on my desk and accidentally dropped it on the floor, they would shut the place down," Yuri Gorby, a microbiologist who'd studied radioactive materials at the U.S. Geological Survey and Department of Energy, told the magazine. "And if I dumped it down the sink, I could go to jail."

Excerpt from a 1982 report prepared for the American Petroleum Institute and titled "An Analysis of the Impact of the Regulation of 'Radionuclides' as a Hazardous Air Pollutant on the Petroleum Industry."

API's report focused on the possibility that the federal government might step in and regulate those radioactive materials under the Clean Air Act or under federal Superfund laws.

"Depending on the mode of definition," the report adds, "very small quantities of petroleum products could easily contain reportable quantities of [radioactive materials]." A chart lists amounts as small as a half a barrel of crude oil or 17 cubic feet of natural gas as containing "one reportable quantity of uranium or radon" under the most restrictive definition.

The report labels uranium "a somewhat different dilemma" than radon gas. "We estimated earlier in this paper that significant quantities of uranium potentially enter our refineries via crude oil," the report continues. "Little is known of its fate, however."

"Since the law of conservation of matter must apply, it can only end up in the product, the process waste, remain in the process equipment, or escape into the environment," the report notes, calling for more study, particularly of the industry's refining equipment and waste.

1982 API Analysis of Radionuclides in Oil and Gas Industry (PDF)
1982 API Analysis of Radionuclides in Oil and Gas Industry (Text)

Some of the report's most stark language warned about the possibility of federal regulation of the industry's radioactive wastes.

"It is concluded that the regulation of radionuclides could impose a severe burden on API member companies," the report says, "and it would be prudent to monitor closely both regulatory actions."

API spokesperson Reid Porter provided to DeSmog the group's response to the Rolling Stone investigation.

"We take each report of safety or health issues related to energy development very seriously," Porter said. "Nothing is more important than the health and safety of our workers, the local environment, and the communities where we live, operate, and raise families. Natural gas and oil companies meet or exceed strict federal and state regulations and also undergo regular inspections to ensure that all materials are managed, stored, transported, and disposed of safely. Through regular monitoring, ongoing testing, and strict handling protocols, industry operations are guided by internationally recognized standards and best practices to provide for safe working environments and public safety."

API also pointed to a one-page document titled "NORM [naturally occurring radioactive materials] in the Oil and Natural Gas Industry." As of publication time, API had not responded to questions from DeSmog regarding the 1982 report.

10 Years Later, Hazards 'Widespread'; 20 Years Later, Workers Sue OverCancers

Over a decade later, problems persisted, other documents indicate. "Contamination of oil and gas facilities with naturally occurring radioactive materials (NORM) is widespread," a 1993 paper published by the Society of Petroleum Engineers warned. "Some contamination may be sufficiently severe that maintenance and other personnel may be exposed to hazardous concentration."

Nonetheless, the paper focused on the potential for "over-regulation."

"Where possible, industry input should be directed to minimize an over-regulation of NORM contamination in the industry," author Peter Gray, an expert on radioactivity who formerly worked for Phillips Petroleum Co., wrote. He added that concentrations of radioactive contamination at the time were "relatively low and do not usually present a health hazard to the public or to most personnel in the industry," but added that some facilities "may be hazardous to maintenance personnel in particular."

Peter Gray NORM Contamination in the Petroleum Industry, 1993 Society of Petroleum Engineers (PDF)
Peter Gray NORM Contamination in the Petroleum Industry, 1993 Society of Petroleum Engineers (Text)

The 1993 paper notes that some oil-producing states had passed or were considering passing laws to protect against the industry's radioactive wastes, noting in particular that Louisiana and Mississippi had regulations in effect, and that Louisiana had required "radiation surveys of every petroleum facility in the state."

But state and federal regulators largely failed to act, Rolling Stone found. "Of 21 significant oil-and-gas-producing states, only five have provisions addressing workers, and just three include protections for the public, according to research by [Elizabeth Ann Glass] Geltman, the public-health expert," the magazine reported. "Much of the legislation that does exist seems hardly sufficient."

In documents dated nearly two decades later, from a 2011 lawsuit brought by more than 30 Louisiana oilfield workers who'd developed cancer, plaintiff's experts described as resulting from their exposure to radioactive materials at work.

The 2013 plaintiff's expert report describes in detail how jobs like roustabout, roughneck, and derrickman can expose workers to radioactive materials, including a sludge where radioactive elements concentrate that collects inside pipes and so-called "pipe scale," or crusty deposits that also attract radioactive materials. The case ended in October 2016, following a long string of settlements on unspecified terms by individual plaintiffs in the case, public court records show.

OCCUPATIONAL EXPOSURES to RADIOACTIVE SCALE and SLUDGE Coleman Et Al v H C (PDF)
OCCUPATIONAL EXPOSURES to RADIOACTIVE SCALE and SLUDGE Coleman Et Al v H C (Text)

Tracking theTrucks

Nobel's Rolling Stone expos depicts radioactive drilling waste sloshing into a striking array of corners.

For example, to keep dust down, the "brine" can be spread on roads, like a stretch in Pennsylvania where Nobel describes a group of Amish girls strolling barefoot. Nobel adds that contractors pick up waste directly from the wellhead and that in 2016 alone, more than 10.5 million gallons were sprayed on roads in the northwestern corner of Pennsylvania.

The waste has also been sold at Lowe's, bottled as "AquaSalina" and marketed as a pet-safe way to fight ice and salt, though an Ohio state lab found it contains radium at more than 40 times the levels the Nuclear Regulatory Commission allows in discharge from industry. And the radium-laced waste is spilled from trucks transporting it, in potential what the article indicates may be a violation of federal law.

One brine truck driver, identified only as a man named Peter from Ohio, started taking his own samples after being told by another worker with a radiation detector that he'd been hauling "one of the 'hottest loads' he'd ever seen," Rolling Stone reports. "A lot of guys are coming up with cancer, or sores and skin lesions that take months to heal," Peter told the magazine. Tests by a university lab found radium levels as high as 8,500 picocuries per liter, the article adds.

One expert, scientist Marvin Reisnikoff, who'd served as one of the plaintiff's experts in the lawsuit brought by the Louisiana oilfield workers and co-authored the 2013 report, told Rolling Stone that a standard brine truck rolling through Pennsylvania might be carrying radioactive wastewater at levels a thousand times higher than those allowed under federal Department of Transportation (DOT) limits. But, a DOT spokesperson told Rolling Stone, federal regulators rely heavily on industry self-reporting, and the rules seem generally unenforced.

Environmental groups immediately called for congressional hearings into the drilling industry's radioactive wastes.

"This alarming report brings into stark relief what we already knew to be true," Food & Water Watch Policy Director Mitch Jones said in a statement calling for a congressional investigation, "that highly toxic and radioactive waste generated by fossil fuel drilling and fracking cannot be stored or disposed of safely, and in fact is often being intentionally dispersed in our communities."

"It is imperative that Congress hold hearings soon to examine and expose the full extent of the threat oil and gas waste poses to families and workers throughout America," he added, "and take urgent action to halt fracking and the legal and illegal dispersal of the waste currently taking place."

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Dengue breakthrough: Scientists develop genetically engineered mosquito to combat the disease – International Business Times, Singapore Edition

January 25th, 2020 1:43 am

A nearly invisible bite delivered by a tiny mosquito has the capacity to trigger the fear of dengue in a human being who is millions of times larger than the insect. Such is the deadliness of the disease. However, one may not have to be harrowed by the fear of contracting the disease anymore.

In an effort to combat the spread of dengue, and counter the virus causing it, scientists at CSIRO, and the University of California San Diego have created a breed of genetically modified mosquito that is resistant to spreading all the four serotypes of the disease.

Talking about the research that is the first engineered approach towards targeting all the four serotypes, Dr Prasad Paradkar, senior research scientist, said in a statement, "In this study we used recent advances in genetic engineering technologies to successfully genetically modify a mosquito, the Aedes aegypti, with reduced ability to acquire and transmit the dengue virus."

Why genetically engineer a mosquito?

Over 390 million people are infected with dengue every year. It is caused by the Dengue virusDENV. Mosquitoes are the only known vectors carrying the disease, only other exception being transmission from mother to foetus. The virus has four serotypes: DENV1, DENV2, DENV3 and DENV4. Therefore, an individual can contract the disease four times due to the prevalence of four distinct strains.

Over half of the world population is at the risk of infection, and the rate of infection has seen an alarming rise over the years. Globally, nearly be $40 billion are lost as a result of dengue every year. This the primary motivation behind the development of the new mosquito, as a resistant vector will be unable to carry the virus.

"Mosquito-transmitted viruses are expected to climb over the coming years, which is why CSIRO is focussed on developing new ways to help solve this global challenge," said Paradkar.

Unlike previous attempts at synthetically engineering mosquitoes that were limited by the ability to target only one or two of the major serotypes, this breed of mosquito has shown the ability to resist all the four. As the scientists point out, this presents the future potential to fight all forms of mosquito-borne illnesses.

"This breakthrough work also has the potential to have broader impacts on controlling other mosquito-transmitted viruses," said Omar Akbari, co-author of the study.

Akbari also added that the research is in the preliminary stages of testing procedures to simultaneously negate mosquitoes against dengue and an array of mosquito-borne viruses such as chikungunya, Zika, and yellow fever.

The disease is typically characterised by symptoms such as severe fever, muscle aches, and headaches. More severe forms of the disease can cause shock, vomiting, haemorrhage, and sometimes, death.

There is no known treatment for specific neutralisation of the disease. Also, there are no vaccinations available against the disease. Treatment includes prescription of drugs such as acetaminophen, also known as paracetamol, to soothe the pain. Hydration through intake of fluids and occasionally intravenously is another remedy.

Stressing on this immediate need for a cure, Paradkar concluded, "There is a pressing global demand for effective strategies to control the mosquitoes that spread the dengue virus, as there are currently no known treatments and the vaccine that is available is only partially effective."

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Dengue breakthrough: Scientists develop genetically engineered mosquito to combat the disease - International Business Times, Singapore Edition

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Online Communion? Theology and the Digital Church – Dr. James Emery White Christian Blog – Crosswalk.com

January 25th, 2020 1:43 am

There are many pressing areas in need of fresh theological thinking in light of a rapidly changing world. The redefinition of family, the nature of sexual identity, artificial intelligence, genetic engineering

and the digital church.

One of the more pressing concerns will be how much tech can and should be used and how in light of an orthodox and robust ecclesiology. Is someone considered attending if its through an internet connection and a virtual reality (VR) headset? Is it appropriate to perform a digital baptism where avatars are immersed in water? What of a completely computer-generated church using VR and augmented reality (AR)? Which, I might add, already exists.

On the most basic of levels, what is to be thought when people participate through an online service but consider themselves a part of a churchthe so-called bedside Baptists and pillow Presbyterians? Or using apps to attend digital events and enter into corporate prayer through emojis and avatars?

There will be a knee-jerk reaction against such innovations, but there can be little doubt that a new way of doing and being church is being forged through technological innovation and an increasingly digital world. In other words, instead of a knee-jerk negative reaction out of distaste or stylistic preference, it demands vigorous theological reflection that takes the digital revolution seriously.

A single blog is grossly insufficient to tackle this task, but perhaps I could suggest one way of thinking about one of the many questions being raised: If someone is involved in an online campus, should they be encouraged to participate in the Lords Supper as they watch?

Again, this is not about a full-blown theology of the online church, much less the only kind of question that can be raised. So lets just treat it as a sample question in need of theological reflection in light of the digital revolution.

My own conclusion? A qualified yes.

When I was in seminary and pastor of a county-seat First Baptist Church, one of the more meaningful ministries of the deacons was taking communion to shut-ins (I dont know whether shut-ins is still the correct term, but that is what we called them.). We offered communion, or the Lords Supper, once a month. We had members of the church who were physically unable to attendthey were in the hospital, in a nursing home, or in their own homes, but not able to physically leave.

So on Sunday afternoons, following the Sunday morning services that we had communion, the deacons of the church fanned out across our little town and brought a communion kit with bread and grape juice to those people so they could also partake.

The deacons spent a few minutes talking with them, read scripture and prayed, reminded them of the churchs love and concern for them, and then shared the bread and the juice with them. It was beautiful and so much the epitome of the church and the sacrament.

And theologically, what could possibly be the problem? They were members/attenders of the church, unable to physically attend and we, as the church, went to them on the days we celebrated communion to include them in the spirit of community and joint celebration of the sacrament.

Fast forward.

Youre celebrating communion as a church in the 2020s, and you have people unable to attend in person who are joining you online. They may be in a hospital, in a nursing home, a shut-in, traveling on business in a hotel room, on vacation and watching as a family, or living in a place where they have no church home and the online service has been their lifelinebecoming the only church home they are able to have.

What do you do?

Could you use the same theological and ecclesiastical reasoning that was applied by my former church?

What if an online campus pastor were to say, For those of you joining us online who cannot be with us physically, go get a bit of bread and some juice or wine, and when we partake as a church, join us as part of that community.

Why is that different from deacons taking it to them?

Today its just the internet taking it to them and they self-serve the elements. Its still done in full honor of the sacrament, under the leadership of pastors, under the authority of the church and in the spirit of community.

So are there limits to online participation in such things as the sacraments? I would argue that there are. Take, for example, baptism. Do we say, For those of you watching online, feel free to fill your bathtub and baptize yourself as we perform the sacrament of baptism as part of this service?

Heavens, no. Why? Because the goal is to think about each and every question being raised by the digital revolution and the online church both biblically and theologically. And the nature of the sacrament of baptism is that it is meant to be a public profession of faith. That means in front of other people. Its for this same reason that you cannot marry yourself. When a couple marries they make public vows, and it is the public nature of the vows that matters.

Such conclusions may not satisfy everyone, nor do they reflect the way to think theologically about all aspects of the online church. Each will bring its own set of unique theological challenges. But perhaps this shows how we are going to have to reflect, and reflect deeply, about the digital world and the churchs operation in that digital world.

These three things I know: We cannot bury our head in the sand as if there are no new questions being posed to the doctrine of the church (there are); we cannot march blindly forward into the digital world as if theology doesnt matter (it does); and we cannot restrain all ecclesiastical innovation as if there hasnt been a digital revolution

(because there has).

James Emery White

Sources

Dalvin Brown, Online Church: Ministries Use VR, Apps to Deliver Digital Services and Virtual Baptisms, USA Today, December 27, 2019, read online.

About the Author

James Emery White is the founding and senior pastor of Mecklenburg Community Church in Charlotte, NC, and the ranked adjunct professor of theology and culture at Gordon-Conwell Theological Seminary, where he also served as their fourth president.His newest book,Christianity for People Who Arent Christians: Uncommon Answers to Common Questions, is nowavailable on Amazonor at your favorite bookseller. To enjoy a free subscription to the Church & Culture blog, visit ChurchAndCulture.org, where you can view past blogs in our archive and read the latest church and culture news from around the world.Follow Dr. White onTwitter,FacebookandInstagram.

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Stem Cell Assay Market Booming by Size, Revenue, Trend and Top Growing Companies 2026 – Vital News 24

January 25th, 2020 1:42 am

Stem Cell Assay Market

New Jersey, United States, The report offers an all-inclusive and accurate research study on the Stem Cell Assay Market while chiefly that specialize in current and historical market scenarios. Stakeholders, market players, investors, and other market participants can significantly have the benefit of the thorough marketing research provided within the report. The authors of the report have compiled an in depth study on crucial market dynamics, including growth drivers, restraints, and opportunities. This study will help market participants to induce a decent understanding of future development of the Stem Cell Assay market. The report also focuses on market taxonomy, regional analysis, opportunity assessment, and vendor analysis to assist with comprehensive evaluation of the Stem Cell Assay market.

Global Stem Cell Assay market was valued at USD 536.53million in 2016 and is projected to reach USD 2858.95millionby 2025, growing at a CAGR of 20.43% from 2017 to 2025.

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Top 10 Companies in the Global Stem Cell Assay Market Research Report:

Global Stem Cell Assay Market: Competitive Landscape

The research analysts who have authored this report are experts in performing competitive analysis of the global Stem Cell Assay market. They have deeply profiled leading as well as other players of the global Stem Cell Assay market with large emphasis on their market share, recent developments, business overview, markets served, and growth strategies. The report not only provides valuable insights into the competitive landscape but also concentrates on minor as well as major factors influencing the business of players. The product portfolios of all companies profiled in the report are compared in quite some detail in the product analysis section.

Global Stem Cell Assay Market: Segment Analysis

The global Stem Cell Assay market is segmented according to type, application, and region. The analysts have carefully studied each segment and sub-segment to provide a broad segmental analysis of the global Stem Cell Assay market. The segmentation study identifies leading segments and explains key factors supporting their growth in the global Stem Cell Assay market. In the regional analysis section, the report authors have shown how different regions and countries are growing in the global Stem Cell Assay market and have predicted their market sizes for the next few years. The segmental analysis will help companies to focus on high-growth areas of the global Stem Cell Assay market.

Global Stem Cell Assay Market: Regional Analysis

This part of the report includes detailed information of the market in different regions. Each region offers different scope to the market as each region has different government policy and other factors. The regions included in the report are North America, South America, Europe, Asia Pacific, and the Middle East. Information about different region helps the reader to understand global market better.

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Table of Content

1 Introduction of Stem Cell Assay Market

1.1 Overview of the Market 1.2 Scope of Report 1.3 Assumptions

2 Executive Summary

3 Research Methodology of Verified Market Research

3.1 Data Mining 3.2 Validation 3.3 Primary Interviews 3.4 List of Data Sources

4 Stem Cell Assay Market Outlook

4.1 Overview 4.2 Market Dynamics 4.2.1 Drivers 4.2.2 Restraints 4.2.3 Opportunities 4.3 Porters Five Force Model 4.4 Value Chain Analysis

5 Stem Cell Assay Market, By Deployment Model

5.1 Overview

6 Stem Cell Assay Market, By Solution

6.1 Overview

7 Stem Cell Assay Market, By Vertical

7.1 Overview

8 Stem Cell Assay Market, By Geography

8.1 Overview 8.2 North America 8.2.1 U.S. 8.2.2 Canada 8.2.3 Mexico 8.3 Europe 8.3.1 Germany 8.3.2 U.K. 8.3.3 France 8.3.4 Rest of Europe 8.4 Asia Pacific 8.4.1 China 8.4.2 Japan 8.4.3 India 8.4.4 Rest of Asia Pacific 8.5 Rest of the World 8.5.1 Latin America 8.5.2 Middle East

9 Stem Cell Assay Market Competitive Landscape

9.1 Overview 9.2 Company Market Ranking 9.3 Key Development Strategies

10 Company Profiles

10.1.1 Overview 10.1.2 Financial Performance 10.1.3 Product Outlook 10.1.4 Key Developments

11 Appendix

11.1 Related Research

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Cell Separation Technology Market Statistics, Demand and Forecasts to 2027 Examined in New Research Report – Dagoretti News

January 25th, 2020 1:42 am

Transparency Market Research (TMR)has published a new report on the globalcell separation technology marketfor the forecast period of 20192027. According to the report, the global cell separation technology market was valued at ~US$ 5 Bnin 2018, and is projected to expand at a double-digit CAGR during the forecast period.

Overview

Cell separation, also known as cell sorting or cell isolation, is the process of removing cells from biological samples such as tissue or whole blood. Cell separation is a powerful technology that assists biological research. Rising incidences of chronic illnesses across the globe are likely to boost the development of regenerative medicines or tissue engineering, which further boosts the adoption of cell separation technologies by researchers.

Expansion of the global cell separation technology market is attributed to an increase in technological advancements and surge in investments in research & development, such asstem cellresearch and cancer research. The rising geriatric population is another factor boosting the need for cell separation technologies Moreover, the geriatric population, globally, is more prone to long-term neurological and other chronic illnesses, which, in turn, is driving research to develop treatment for chronic illnesses. Furthermore, increase in the awareness about innovative technologies, such as microfluidics, fluorescent-activated cells sorting, and magnetic activated cells sorting is expected to propel the global cell separation technology market.

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North America dominated the global cell separation technology market in 2018, and the trend is anticipated to continue during the forecast period. This is attributed to technological advancements in offering cell separation solutions, presence of key players, and increased initiatives by governments for advancing the cell separation process. However, insufficient funding for the development of cell separation technologies is likely to hamper the global cell separation technology market during the forecast period. Asia Pacific is expected to be a highly lucrative market for cell separation technology during the forecast period, owing to improving healthcare infrastructure along with rising investments in research & development in the region.

Rising Incidences of Chronic Diseases, Worldwide, Boosting the Demand for Cell Therapy

Incidences of chronic diseases such as diabetes, obesity, arthritis, cardiac diseases, and cancer are increasing due to sedentary lifestyles, aging population, and increased alcohol consumption and cigarette smoking. According to the World Health Organization (WHO), by 2020, the mortality rate from chronic diseases is expected to reach73%, and in developing counties,70%deaths are estimated to be caused by chronic diseases.

Southeast Asia, Eastern Mediterranean, and Africa are expected to be greatly affected by chronic diseases. Thus, the increasing burden of chronic diseases around the world is fuelling the demand for cellular therapies to treat chronic diseases. This, in turn, is driving focus and investments on research to develop effective treatments. Thus, increase in cellular research activities is boosting the global cell separation technology market.

Increase in Geriatric Population Boosting the Demand for Surgeries

The geriatric population is likely to suffer from chronic diseases such as cancer and neurological disorders more than the younger population. Moreover, the geriatric population is increasing at a rapid pace as compared to that of the younger population. Increase in the geriatric population aged above 65 years is projected to drive the incidences of Alzheimers, dementia, cancer, and immune diseases, which, in turn, is anticipated to boost the need for corrective treatment of these disorders. This is estimated to further drive the demand for clinical trials and research that require cell separation products. These factors are likely to boost the global cell separation technology market.

According to the United Nations, the geriatric population aged above 60 is expected to double by 2050 and triple by 2100, an increase from962 millionin 2017 to2.1 billionin 2050 and3.1 billionby 2100.

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Productive Partnerships in Microfluidics Likely to Boost the Cell Separation Technology Market

Technological advancements are prompting companies to innovate in microfluidics cell separation technology. Strategic partnerships and collaborations is an ongoing trend, which is boosting the innovation and development of microfluidics-based products. Governments and stakeholders look upon the potential in single cell separation technology and its analysis, which drives them to invest in the development ofmicrofluidics. Companies are striving to build a platform by utilizing their expertise and experience to further offer enhanced solutions to end users.

Stem Cell Research to Account for a Prominent Share

Stem cell is a prominent cell therapy utilized in the development of regenerative medicine, which is employed in the replacement of tissues or organs, rather than treating them. Thus, stem cell accounted for a prominent share of the global market. The geriatric population is likely to increase at a rapid pace as compared to the adult population, by 2030, which is likely to attract the use of stem cell therapy for treatment. Stem cells require considerably higher number of clinical trials, which is likely to drive the demand for cell separation technology, globally. Rising stem cell research is likely to attract government and private funding, which, in turn, is estimated to offer significant opportunity for stem cell therapies.

Biotechnology & Pharmaceuticals Companies to Dominate the Market

The number of biotechnology companies operating across the globe is rising, especially in developing countries. Pharmaceutical companies are likely to use cells separation techniques to develop drugs and continue contributing through innovation. Growing research in stem cell has prompted companies to own large separate units to boost the same. Thus, advancements in developing drugs and treatments, such as CAR-T through cell separation technologies, are likely to drive the segment.

As per research, 449 public biotech companies operate in the U.S., which is expected to boost the biotechnology & pharmaceutical companies segment. In developing countries such as China, China Food and Drug Administration(CFDA) reforms pave the way for innovation to further boost biotechnology & pharmaceutical companies in the country.

Global Cell Separation Technology Market: Prominent Regions

North America to Dominate Global Market, While Asia Pacific to Offer Significant Opportunity

In terms of region, the global cell separation technology market has been segmented into five major regions: North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. North America dominated the global market in 2018, followed by Europe. North America accounted for a major share of the global cell separation technology market in 2018, owing to the development of cell separation advanced technologies, well-defined regulatory framework, and initiatives by governments in the region to further encourage the research industry. The U.S. is a major investor in stem cell research, which accelerates the development of regenerative medicines for the treatment of various long-term illnesses.

The cell separation technology market in Asia Pacific is projected to expand at a high CAGR from 2019 to 2027. This can be attributed to an increase in healthcare expenditure and large patient population, especially in countries such as India and China. Rising medical tourism in the region and technological advancements are likely to drive the cell separation technology market in the region.

Launching Innovative Products, and Acquisitions & Collaborations by Key Players Driving Global Cell Separation Technology Market

The global cell separation technology market is highly competitive in terms of number of players. Key players operating in the global cell separation technology market include Akadeum Life Sciences, STEMCELL Technologies, Inc., BD, Bio-Rad Laboratories, Inc., Miltenyi Biotech, 10X Genomics, Thermo Fisher Scientific, Inc., Zeiss, GE Healthcare Life Sciences, PerkinElmer, Inc., and QIAGEN.

These players have adopted various strategies such as expanding their product portfolios by launching new cell separation kits and devices, and participation in acquisitions, establishing strong distribution networks. Companies are expanding their geographic presence in order sustain in the global cell separation technology market. For instance, in May 2019, Akadeum Life Sciences launched seven new microbubble-based products at a conference. In July 2017, BD received the U.S. FDAs clearance for its BD FACS Lyric flow cytometer system, which is used in the diagnosis of immunological disorders.

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Cell Separation Technology Market Statistics, Demand and Forecasts to 2027 Examined in New Research Report - Dagoretti News

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UFO Religion the Ralians Know They’re ‘Quite Out There’ – VICE UK

January 25th, 2020 1:42 am

"The only difference between us and anybody else is that we believe all life was created by the Elohim, who were extra-terrestrials visiting Earth from another planet," Glenn Carter, president of the British Ralian movement, explains to me. "The rest of our behaviour is the same as any other human being, or group."

The Ralian movement, known to many as a "UFO religion", started in France in the 1970s. Their prophet a French former journalist and pop star called Ral (born Claude Vorilhon) claims that the origins of all life on Earth were explained to him during an alien encounter in 1973. The message he was given by the visitors became the Ralian philosophy, which he released in books that include The Book Which Tells the Truth and Extraterrestrials Took Me to Their Planet.

The belief system is one that argues for personal and sexual freedom, love, science and technological advancement. Oh, and that humans were put here thousands of years ago by aliens (or "advanced humans from another planet", to be exact) as an experiment. Since then, Ral has led this "atheist religion" through social justice campaigns, televised debates and battles with bad press, amassing hundreds of thousands of devoted followers from Canada to Japan.

Glenn Carter. Photo by the author.

"We were created in the image of another humanity," Glenn tells me over a pint in Leigh-on-Sea, Essex, before comparing life on Earth to the Eden Project in Cornwall. "They monitor us and wish one day to return to share their scientific knowledge [...] I discovered the philosophy in a bookshop and contacted the organisation. Eventually, they asked me to run it here," he explains.

Outside of his beliefs, Glenn is an actor known for playing Jesus in the Broadway, West End and movie versions of Jesus Christ Superstar a career that took a hit when he accepted the presidency.

"It has affected my life incredibly through the bigotry of other people," says Glenn, now in his fifties. "I won't be employed by certain producers I was really on the rise as a West End actor in musical theatre; I was on Broadway, winning awards, appearing in films, and the whole thing completely stopped as soon as an actress I worked with said, 'He's the guy that believes in aliens and he runs the Ralian movement'"

The creators the Ralians believe in are known as the Elohim, which, according to the prophet Ral, means "those who came from the sky" in the original Hebrew it's translated from. In Christianity and Judaism, the word simply means "God", but there has been much debate and disagreement around the translation of the word. It does appear to be plural, which indicates it could possibly translate to "gods" as opposed to God.

This speculation about ancient astronauts isn't unique to Ralism. Books like Erich von Daniken's 1968 epic Chariots of the Gods? and The Spaceships of Ezekial, written by a NASA engineer named Josef F Blumrich in 1974, popularised theories that Earth was visited long ago by extraterrestrials, and that some of those visitations even appear in religious scriptures.

Unpacking and reinterpreting stories from the Old Testament concerns much early Ralian literature. According to Ral, the Bible and other holy books are full of alien encounters and messages, but they've been misinterpreted over time. With this in mind, they believe that the prophets from all other religions were actually preaching messages from the Elohim, too including Ral's alleged half-brothers Jesus, Mohammed and Buddha.

UK Ralians and the author (second from left) at a dinner celebrating the first encounter.

"I think the best thing about the Ralian movement is that it encourages people to be free. That's what drew me to it," says Jamie, an IT technician and recent convert, at one of their monthly meet-ups. He used to identify with Buddhist teachings, but his old Christian church said they were "bad spirituality". He tells me Ralians remind him of the Buddhists he's met, that "they are very kind and have inner peace The main criticism of Ralianism is its size. Because it's very small, it's seen as a cult. People are scared of it."

Jamie was introduced to Ralism by a veteran UK member named Sakina, while she was working as a stripper: "He came to me one night, and simply by the way I connected, and the tender way I made him feel welcome," she says, "he asked me, 'What do you feel about life?'"

The pair started talking meditation and ended up at Ralian philosophy, with Jamie eventually subscribing to the belief system.

Unlike Sakina, however, not all Ralians openly discuss their faith in the workplace take Karen, for instance, who found the movement in her late fifties: "I work for the Metropolitan Police Service, which is very diverse and encourages diversity, but I know that if I was to say where I was coming from, [some people] would find that quite difficult. And, to be honest, I don't think they need to know."

I ask what her family think about her beliefs. "When I first told my husband, he was absolutely fine with it he's an atheist himself," she says. "The only concern he had was that it might be a cult and would they be taking me away from him? Three years down the line, we're still together, nothing has changed."

What about her son? "He's 30 and finds it amusing. He doesn't believe in anything himself. When I told him about the Ralian movement he went online and saw all these things about sex orgies [laughs] For his mum to be involved with that kind of organisation was really funny to him. He takes it with a pinch of salt."

Sex and promiscuity have been associated with the sect for decades, salacious articles appearing in tabloid newspapers, "Ral's Girls" popping up in Playboy magazine. It's true that the philosophy promotes sexual freedom, but the members I speak to insist that sex is found in the movement no more than it is anywhere else.

"I guarantee that lots of people have had sex in the Ralian movement with people they've met in the Ralian movement," says Glenn. "But the same thing happens at Barclays bank, between teachers at high schools, or wherever. Nothing is organised by the Ralian movement. It would be a waste of time because we've got so many other things to discuss and do."

Sandra is a Swedish-born Ralian living in London. She works in the tourism business and was hosting the monthly meeting in her central London office space one Sunday morning. "It's been quite hard sometimes, in my relationship with my friends. They all felt it was so strange," she explains earnestly. "But the Ralian values have always been my values."

Sandra found the religion through her interest in musical theatre, a fan of Glenn's who decided to email him on a whim. Eight years later she is an active member, organising events and getting involved in Free Meditation campaigns around the UK.

It's difficult to find anything written about the community that doesn't dismissively brand it a "cult" old VICE coverage included. I ask Glenn how this feels. "It's offensive it's literally like using the N-word to describe a black person," he says, perhaps underestimating the weight of using "literally" in this comparison. "The word 'cult' means, in its original sense, 'system of religious worship'. So, Christianity is a cult because it's a system of religious worship. So is Judaism, Islam and every religion you can name! It's designed to colour people's opinions of you, but that's just their own stupid insecurities."

These thoughts are echoed by Tomi, a long-haired Ralian rocker who lives in Liverpool: "It's a way to discredit us, because the old religions and the establishment, they are afraid of this message. We are a true revolution in all aspects of life."

Tomi is the president of the Romanian Ralian branch and has appeared all over Romanian TV. When I first met him in London he embraced me passionately and said, "You are my brother," a metal Ralian symbol hanging from his neck. Shortly after, we stood in a circle with some other followers, closed our eyes and attempted to make contact with the Elohim. The "transmission" was somewhere between a guided meditation and a good old-fashioned prayer, and although we got no response from the Elohim, everybody was thankful afterwards.

Ralian pensioners in the garden in Norfolk. Photo: provided.

After early coverage of the movement and a multitude of TV interviews with their founder through the 1980s and 90s, the organisation could have slipped quietly out of the public eye. However, in 2002 they made international headlines when Dr Brigitte Boisselier a Ralian bishop with a PhD in Analytical Chemistry claimed the group had cloned a human baby. The movement are big advocates for cloning, setting up the organisation Clonaid in 1997, dedicated to their quest for immortality. "Ralians believe there is no afterlife at all," Glenn tells me. "The only afterlife is the one that science could create for you."

As the president of UK Ralians, Glenn appeared on TV a lot at that time to defend cloning from an ethical and philosophical standpoint. This claim, and the debates that followed, drew a lot of attention to the religion, and even inspired a piss-taking sketch on Saturday Night Live. "Cloning is happening all the time, every day," says Glenn, confidently. "The only difference between stem-cell therapies and reproductive human cloning is that, in stem-cell therapies, you end the life that is developing, you harvest the cells and you don't allow it to grow."

Dr Boisselier never provided proof that Clonaid had cloned baby "Eve", and at the time the whole saga was criticised as a hoax by both journalists and scientists. When asked, Glenn can't say for certain if it really happened either.

As well as Clonaid, Ralians also started an anti-FGM charity called Clitoraid, campaigned to rehabilitate the swastika (a symbol they use as their own, placed inside the star of David), staged topless protests for equality, supported gay Pride events worldwide and even tried to sue the Pope over child sexual abuse in the Vatican. Some of their tactics in the fight for social justice have, admittedly, not helped their reputation like the time they handed out 10,000 condoms to students in Montreal to protest the Catholic School Commission's decision to veto high school condom machines. However, this doesn't stop them from fighting the good fight. "Fuck the oppression that society puts on us," says Glenn.

When I ask about UFO encounters, some members come forward with their stories all fairly classic lights-in-the-sky anecdotes, but without the usual fear and bewilderment. "Each time, I had a huge sensation of warmth, and sometimes a little tear," Sakina tells me, wistfully. "To witness it was such a beautiful thing."

The Ralian idea that we're being watched from above isn't just one for religious circles; even scientists and astronomers have entertained the idea known as the "zoo hypothesis".

On my last visit to the group, we gather on the 13th of December at a restaurant in Londons Docklands, called Area 51 Tex Mex to celebrate the anniversary of the prophet's first alien encounter. We watch a video from one of their Happiness Academy events essentially a big Ralian get-together and, although the nudity in it probably doesn't help their "sex cult" reputation, I can't deny it looks way more fun than any Sunday service I've attended.

As well as being a "religion-for-atheists" where freedom reigns supreme, Ralism's lasting pull is also identified as its championing of science.

"I've always been into the science part of it," Sandra tells me. "Finding spirituality together with science really spoke to me." She then goes onto casually tell me that "evolution was disproved in 1993", citing Dr Michael Behe and his theory of Irreducible Complexity a theory positing that humanity is the result of intelligent design, and one that has been rejected by the majority of the scientific community.

As the meeting draws to a close, I ask how it feels to regularly watch their white-clad prophet, Ral, face laughter and ridicule from journalists and TV audiences. "For me, it is hard. We have all experienced that in some way," says Sandra. "We are quite 'out-there', and that makes people insecure. I just try to have compassion for the people that think in that way."

Ralism is not without its unanswered questions and ambiguities and its past isn't entirely unblemished, but which religion is? Where other spiritual groups have grown and (sometimes literally) died out, imploded or been abandoned, this philosophy is seemingly more robust. The movement may never entirely shake off their "sex cult" reputation or be taken seriously as a religion, but the members I meet don't seem to mind too much. In fact, they're all too happy and devoted to care.

@Jak_TH

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UFO Religion the Ralians Know They're 'Quite Out There' - VICE UK

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Take care of your eyes by making healthy eating choices – Western Producer

January 25th, 2020 1:41 am

With the arrival of the year 2020 we are reminded that this number is often recognized as an indicator of perfect vision.

It seems appropriate in the year 2020 to consider what nutrients and foods preserve and promote vision health.

Making healthy lifestyle and diet choices can help keep our eyes healthy and may prevent age-related eye diseases, such as sight loss, dry eyes, age-related macular degeneration (AMD), cataracts, and problems with night vision.

Our eyes, like the rest of our body, benefit when we eat a balanced diet. However, there are several key nutrients that are particularly good for maintaining eye health.

Vitamin A is a fat-soluble vitamin that helps the retina to absorb light. Vitamin A deficiency is most common in developing countries. Some of the first signs of this deficiency are dry eyes and night blindness.

There are two types of vitamin A found in foods: preformed vitamin A, also known as retinol, and pro-vitamin A, known as beta carotene. Meat, fish, eggs and dairy products are common sources of vitamin A.

The body converts beta-carotene into vitamin A. A diet rich in beta-carotene helps eyes adjust to low levels of light at night. Orange-coloured fruits and vegetables like oranges, apricots, carrots, pumpkin, squash, and sweet potatoes, get their tint from the beta-carotene. High levels of this pigment are also found in parsley, spinach, kale, egg yolk, collard greens, butter, liver and cod liver oil. Some of these foods are rich in both vitamin A and beta-carotene.

To maximize the availability of the beta-carotenes, the foods should be eaten raw or lightly steamed.

Zinc is a mineral that helps release vitamin A from the liver and drive vitamin A to the retina to produce melanin, which helps protect our eyes from ultraviolet light. It can also help delay age-related sight loss and macular degeneration.

The eye itself contains high levels of zinc, particularly in the retina, and the vascular tissue surrounding the retina. Legumes like beans, peas, chickpeas and lentils add zinc to the diet. Beef is also rich in zinc; chicken breast and pork loin contain lower levels.

Vitamin C contributes to healthy blood vessels in the eye. As an antioxidant it fights against age-related eye damage and helps to absorb some of the harmful rays generated by the sun. Vitamin C is found mainly in vegetables and fresh fruits including lemons, oranges, grapefruits, strawberries and bell peppers. Kiwi is the highest fruit source of vitamin C, making it the top eye food in the fruit category. Broccoli is also a high source of vitamin C and contains lutein and zeaxanthin.

Lutein and zeaxanthin are two nutrients with antioxidant qualities that help protect against the damaging effects of UV rays. Because part of the back of the eye is made up of lutein and zeaxanthin pigment, it is essential to keep the body nourished with these minerals to maintain healthy eyes. Essentially, lutein acts like a pair of sunglasses helping to protect the retina.

Leafy green vegetables are rich in both lutein and zeaxanthin and are also a good source of vitamin C.

This combination of nutrients has the potential to reduce the progress of age-related macular degeneration and vision loss. Well-known leafy greens include spinach, kale, romaine lettuce and broccoli. Other food sources of lutein and zeaxanthin include eggs, zucchini, corn, garden peas, brussels sprouts and blueberries.

Vitamin E is another important antioxidant that protects the eyes from free-radical damage. Oxidation can cause our body to deteriorate and become prone to disease, but vitamin E protects cells in the body from this effect. It can also potentially decrease the progression of cataracts and age-related macular degeneration. Adding wheat germ to baking or as a topping on salads, oatmeal, yogurt, soups, or smoothies is an easy way to add vitamin E to the diet. Other sources of vitamin E are almonds, hazelnuts, sunflower seeds, carrots and sweet potatoes.

Omega-3 fatty acids help to protect adults from both age related macular degeneration and dry-eye syndrome. Omega-3 helps modulate the inflammation that can lead to dry eyes. Some studies have found that fish oil can reverse dry eye, including dry eye caused by too much screen time.

Oily fish are those that have oil in their gut and body tissue, and eating them offers higher levels of omega-3-rich fish oil. The fish that contains the most beneficial levels of omega-3s include tuna, salmon, trout, mackerel, sardines, anchovies and herring.

Nuts, legumes and seeds are rich in omega-3 fatty acids and also contain high levels of vitamin E. Consider incorporating walnuts, Brazil nuts, cashews, peanuts, lentils, chickpeas, ground flax seed, chia seeds and hemp seeds into your meals as garnishes or snacks.

Water is vital for eye health. Without proper hydration, your body can no longer produce tears, or keep your eyes moisturized, which may lead to eye strain or dry eye. Blurry vision, eye fatigue, and headaches are all signs that you need to drink more water.

It is recommended that healthy adults consume six to eight, eight-ounce servings of water each day. To ensure you drink enough, keep a water bottle with you and set reminders for yourself to take in more fluids, especially after physical activity.

It should be noted that diets excessively high in sugar and refined carbohydrates are a risk factor for cataracts.

Few protein sources are better than salmon when it comes to eye health. Packed with omega-3 fatty acids, salmon can help with eye inflammation and reduce the effects of vision conditions such as age-related macular degeneration, cataracts, and dry eyes syndrome.

Spinach is one of the healthiest vegetables available, full of vitamins A, B, and K, iron, and calcium, among other nutrients. The benefits of these nutrients range from acting as an anti-inflammatory and antioxidant to maintaining bone health and helping control blood pressure. Spinach also contains lutein and zeaxanthin, which are primary antioxidants in the eye that can promote eye health and help prevent eye problems such as macular degeneration.

Place the salmon in a non-stick frying pan on medium heat or use a counter top grill.

Turn after roughly four minutes on each side. The salmon should be lightly browned on the outside and slightly transparent on the inside.

While the salmon cooks, mix together the oil, vinegar, honey and Dijon mustard in a separate bowl to create the dressing.

In a large mixing bowl, pour the dressing over the spinach and add the blueberries, capers, orange or grapefruit and onions. Toss well.

Divide the salad onto two plates and top each salad with a salmon filet and a garnish of ground flax seed.

Serve immediately and enjoy!

Adapted from fyidoctors.com/assets/FYidoctors-Eats-For-Your-Eyes-Cookbook-Vol-1.pdf.

Sources: Canadian Association of Optometrists, The American Optometric Association, fyidoctors.com and healthline.com

Betty Ann Deobald is a home economist from Rosetown, Sask., and a member of Team Resources. Contact: team@producer.com.

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Sight for All United Dispensing 600+ Pairs of Glasses to Kids – businessjournaldaily.com

January 25th, 2020 1:41 am

YOUNGSTOWN, Ohio The nonprofit Sight for All United is partnering with Eye Care Associates and Classic Optical Laboratories Inc. to dispense 614 pairs of glasses to children in need at Youngstown and Liberty schools this week.

While schools are required to annually screen and identify kids for vision difficulties, more than half of those identified never get an eye exam. In December 2019, Sight for All United five exam lanes in each school, providing full eye exams for children who failed vision screenings conducted by school nurses and organized by United Way of Youngstown and the Mahoning Valley.

After an eye exam, children selected frames for glasses provided by Classic Optical Laboratories. Each child will receive two pairs of glasses one for home and one for school.

Area eye doctors provided the screenings, including Drs. John Conrad, Nick Lawrence, Chris Shoemaker, Guy Barrett, Pete Sforza, Mike Woloschak, Ryan Maceyko, Brandon Maceyko, Lindsey Foster, Frank DApolito and Sergul Erzurum. All services were provided free of charge through Sight for All United and donations from DentaQuest, Essilor Vision Foundation and Classic Optical Laboratories.

Pictured: Beth Landers, Classic Optical Laboratories customer service representative, and Kim Blazek, licensed optician, assist a student with selecting frames. Image courtesy of Sight for All United.

Published by The Business Journal, Youngstown, Ohio.

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Thousands of South Africans could go blind while waiting for cataract treatment – All4Women

January 25th, 2020 1:41 am

An estimated 290 000 South Africans could become blind as a result of untreated cataracts, with government facilities in most provinces unable to meet the demand for eyesight-saving surgery and waiting-lists stretching well over a year

The Right to Sight Trust, the philanthropic arm of the Ophthalmological Society of South Africa (OSSA), has contributed over R50 million in services over the past three years to vision-restoring operations, but has now run out of funds to cover the cost of vital surgical consumables, like intraocular lens (IOL) implants that restore vision.

The Right to Sight Trust chairperson, Dr Bayanda Mbambisa, said on Thursday that, although they have been able to assist in improving access to high quality eye-care for those in need through the Second Sight Project, the organisation will struggle to accomplish its goals of ending preventable blindness in the target year of 2020.

The Right to Sight Trust and the Second Sight project, and its forerunner Eyecare 2000, are OSSAs response to the World Health Organisations (WHO) call for all countries globally to eliminate avoidable blindness by 2020.

The Second Sight Project enables cataract sufferers from low-income households who are unable to afford private medical care and have been on a public hospital waiting list for over a year to access sponsored cataract surgery.

Our initiative partners with the private and public sectors in realising the WHOs Vision 2020 ask. In the past three years, we have helped 2 071 people in South Africa. Based on a conservative estimate that one cataract sufferer impacts the lives of six people, over 12 400 individuals have benefited indirectly through this partnership that restores patients independence along with their sight, said Mbambisa.

Yet, as we enter 2020, the target year set by WHO, funds are dwindling. Its devastating that the project is once more struggling to accomplish its mission, she said.

South Africas national cataract surgery rate lags far behind international norms, even for developing countries, with the number of surgeries performed declining since the mid-2000s as government focus and funding shifted towards higher priority medical conditions.

Second Sights partnership approach includes ophthalmologists in private practice, and their anaesthetist colleagues, who donate their time and skills; private hospitals providing theatre time, and funding partners and sponsors that provide IOL lenses and consumables for cataract surgery.

Ophthalmologists who perform pro-bono surgeries are reimbursed for consumables used during the surgeries. In the annual Eye Care Awareness Week in October, medical device companies and other sponsors give ophthalmologists access to IOLs and other consumables.

Mbambisa said that in 2019, five medical device companies and three financial donors partnered on the project, with 85 ophthalmologists performing regular monthly surgeries as well as during Eye Care Awareness Week.

In 2019 alone we helped 646 people regain their sight. Whilst the bulk of the cost for the surgeries are borne by ophthalmologists and hospitals that provide free time and theatre space, there is an urgent need for funding to cover the consumables that are essential to surgery. Funding is the only obstacle that stands between this highly effective partnership model and our ability to provide sight saving surgeries.

Every donation restores the sight and dignity of one patient and filters down to a better quality of life for family members and friends who have been caring for the blind or partially sighted individual with significant positive impact on the economic and social health of families and communities. We urge those in a position to assist financially, to support us in caring for those who have no other means.

To find out how corporates can support the Second Sight Project, contact Cindy Busk, National OSSA Right to Sight Operations Manager at [emailprotected] or 082 600 5970.

Author: ANA Newswire

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Europes guardian of stem cells and hopes, real and unrealistic – Daily Times

January 23rd, 2020 11:46 pm

Poland has emerged as Europes leader in stem cell storage, a billion-dollar global industry that is a key part of a therapy that can treat leukaemias but raises excessive hopes.

Submerged in liquid nitrogen vapour at a temperature of minus 175 degrees Celsius, hundreds of thousands of stem cells from all over Europe bide their time in large steel barrels on the outskirts of Warsaw.

Present in blood drawn from the umbilical cord of a newborn baby, stem cells can help cure serious blood-related illnesses like leukaemias and lymphomas, as well as genetic conditions and immune system deficits.

Polish umbilical cord blood bank PBKM/FamiCord became the industrys leader in Europe after Swiss firm Cryo-Save went bankrupt early last year.

It is also the fifth largest in the world, according to its management, after two companies in the United States, a Chinese firm and one based in Singapore.

Since the first cord blood transplant was performed in France in 1988, the sector has significantly progressed, fuelling hopes.

Health insurance

Mum-of-two Teresa Przeborowska has firsthand experience.

At five years old, her son Michal was diagnosed with lymphoblastic leukaemia and needed a bone marrow transplant, the entrepreneur from northern Poland said.

The most compatible donor was his younger sister, Magdalena.

When she was born, her parents had a bag of her cord blood stored at PBKM.

More than three years later, doctors injected his sisters stem cells into Michals bloodstream.

It was not quite enough for Michals needs but nicely supplemented harvested bone marrow.

As a result, Michal, who is nine, is now flourishing, both intellectually and physically, his mum told AFP.

A cord blood transplant has become an alternative to a bone marrow transplant when there is no donor available, with a lower risk of complications.

Stem cells taken from umbilical cord blood are like those taken from bone marrow, capable of producing all blood cells: red cells, platelets and immune system cells.

When used, stem cells are first concentrated, then injected into the patient. Once transfused, they produce new cells of every kind.

At the PBKM laboratory, each container holds up to 10,000 blood bags Safe and secure, they wait to be used in the future, its head, Krzysztof Machaj, said.

The bank holds around 440,000 samples, not including those from Cryo-Save, he said.

If the need arises, the blood will be ready to use without the whole process of looking for a compatible donor and running blood tests, the biologist told AFP.

For families who have paid an initial nearly 600 euros ($675) and then an annual 120 euros to have the blood taken from their newborns umbilical cords preserved for around 20 years, it is a kind of health insurance promising faster and more effective treatment if illness strikes.

But researchers also warn against unrealistic expectations.

Beauty products

Haematologist Wieslaw Jedrzejczak, a bone marrow pioneer in Poland, describes promoters of the treatment as sellers of hope, who make promises that are either impossible to realise in the near future or downright impossible to realise at all for biological reasons.

He compares them to makers of beauty products who swear their cream will rejuvenate the client by 20 years.

Various research is being done on the possibility of using the stem cells to treat other diseases, notably nervous disorders. But the EuroStemCell scientist network warns that the research is not yet conclusive.

There is a list of almost 80 diseases for which stem cells could prove beneficial, US haematologist Roger Mrowiec, who heads the clinical laboratory of the cord blood programme Vitalant in New Jersey, told AFP. But given the present state of medicine, they are effective only for around a dozen of them, like leukaemia or cerebral palsy, he said.

Its not true, as its written sometimes, that we can already use them to fight Parkinsons disease or Alzheimers disease or diabetes.

EuroStemCell also cautions against private blood banks that advertise services to parents suggesting they should pay to freeze their childs cord blood in case its needed later in life.

Studies show it is highly unlikely that the cord blood will ever be used for their child, the network said.

It also pointed out that there could be a risk of the childs cells not being useable anyway without reintroducing the same illness.

Some countries, such as Belgium and France, are cautious and ban the storage of cord blood for private purposes. Most EU countries however permit it while imposing strict controls.

Rapid growth

In the early 2000s, Swiss company Cryo-Save enjoyed rapid growth.

Greeks, Hungarians, Italians, Spaniards and Swiss stored blood from their newborns with the company for 20 years on payment of 2,500 euros upfront.

When the firm was forced to close in early 2019, clients were left wondering where their stem cells would end up.

Under a kind of back-up agreement, the samples of some 250,000 European families were transferred for storage at PBKM.

The Polish firm, founded in 2002 with two million zlotys (around 450,000 euros, $525,000), has also grown quickly.

Present under the FamiCord brand in several countries, PBKM has some 35 percent of the European market, excluding Cryo-Save assets.

Over the last 15 months, outside investors have contributed 63 million euros to the firm, PBKMs chief executive Jakub Baran told AFP.

But the company has not escaped controversy: the Polityka weekly recently published a critical investigative report on several private clinics that offer what was described as expensive treatment involving stem cells held by PBKM.

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Psychiatric body condemns use of stem cell therapies to treat psychiatric disorders – Moneycontrol.com

January 23rd, 2020 11:45 pm

The Indian Psychiatric Society (IPS) the professional body that represents psychiatrists in India, strongly condemned the use of stem cell therapy in psychiatric disorders, particularly autism, until such a time that research evidence substantiated its effectiveness.

IPS, in its position statement on stem cell therapy on January 17, said that till now, there is no scientifically validated and scrutinized research evidence that proves that stem cells are helpful in any psychiatric disorders including autism.

Autism is a complex neurodevelopmental disorder with no known single cause.

The advisory from the IPS comes at a time when stem cell therapy clinics that claim to have developed stem cell therapies to treat complex psychiatric problems such as autism, cerebral palsy (movement disorder), muscular dystrophy (weakness of muscles), mental retardation, spinal cord injury and brain stroke have mushroomed across the country.

These stem cell therapy centres extract stem cells from the bone marrow of each child and then inject it into the childs spinal canal. The whole procedure takes place under general anaesthesia.

These clinics use aggressive marketing techniques and false claims to lure parents of children who are suffering from disease like autism.

The Indian Council of Medical Research (ICMR) has already published guidelines that cover the various diseases that are applicable for stem cell treatment. No psychiatric disorders, including autism, are listed there under this advisory.

Stem cells are special human cells that have the ability to develop into many different cell types, from muscle cells to brain cells. In some cases, they also have the potential to repair damaged tissues, and provide a cure for various diseases. But the clinical evidence at this point is low.

Psychiatric disorders including autism are combined derangements of both neurodevelopmental and neurodegenerative trajectories of brain and are polygenetic in origin. So they actually are symptomatic manifestations of a variety of different pathogenetic processes about which scientific evidence is as yet inconclusive, IPS said.

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What Will Be The Growth of Animal Stem Cell Therapy Market? Dagoretti News – Dagoretti News

January 23rd, 2020 11:45 pm

Latest release from SMI with title Animal Stem Cell Therapy Market Research Report 2019-2026 (by Product Type, End-User / Application and Regions / Countries) provides an in-depth assessment of the Animal Stem Cell Therapy including key market trends, upcoming technologies, industry drivers, challenges, regulatory policies, key players company profiles and strategies. Global Animal Stem Cell Therapy Market study with 100+ market data Tables, Pie Chat, Graphs & Figures is now released BY SMI. The report presents a complete assessment of the Market covering future trends, current growth factors, attentive opinions, facts, and industry-validated market data forecast until 2026.

Global Animal Stem Cell Therapy Market Segmentations

The segmentation chapter allows readers to understand aspects of the Global Animal Stem Cell Therapy Market such as products/services, available technologies, and applications. These chapters are written in a way that describes years of development and the process that will take place in the next few years. The research report also provides insightful information on new trends that are likely to define the progress of these segments over the next few years.

Download FREE Sample Report with Latest Industry Trends 2019 @ https://www.stratagemmarketinsights.com/sample/11599(**Note: Free Sample Copy Only with TOC, Graph, Charts)

Global Animal Stem Cell Therapy Market and Competitive Analysis

Know your current market situation! Not only an important element for new products but also for current products given the ever-changing market dynamics. The study allows marketers to stay in touch with current consumer trends and segments where they can face a rapid market share drop. Discover who you really compete against in the marketplace, with Market Share Analysis know market position, % market Share and Segmented Revenue of Animal Stem Cell Therapy Market

Segmentation and Targeting

Essential demographic, geographic, psychographic and behavioral information about business segments in the Animal Stem Cell Therapy market is targeted to aid in determining the features company should encompass in order to fit into the business requirements. For the Consumer-based market the study is also classified with Market Maker information in order to better understand who the clients are, their buying behavior and patterns.

*** For the global version, a list of below countries by region can be added as part of customization at minimum cost.North America (United States, Canada & Mexico)Asia-Pacific (Japan, China, India, Australia, etc)Europe (Germany, UK, France, etc)Central & South America (Brazil, Argentina, etc)Middle East & Africa (United Arab Emirates, Saudi Arabia, South Africa, etc)

Animal Stem Cell Therapy Product/Service Development

Knowing how the product/services fit the needs of clients and what changes would require to make the product more attractive is the need of an hour. Useful approaches to focus group by utilizing User Testing and User Experience Research. Demand-side analysis always helps to correlate consumer preferences with innovation.

Marketing Communication and Sales Channel

Understanding marketing effectiveness on a continual basis help determine the potential of advertising and marketing communications and allow us to use best practices to utilize an untapped audience. In order to make marketers make effective strategies and identify why the target market is not giving attention, we ensure the Study is Segmented with appropriate marketing & sales channels to identify potential market size by Revenue and Volume* (if Applicable).

Pricing and Forecast

Pricing/subscription always plays an important role in buying decisions; so we have analyzed pricing to determine how customers or businesses evaluate it not just in relation to other product offerings by competitors but also with immediate substitute products. In addition to future sales Separate Chapters on Cost Analysis, Labor*, production* and Capacity are Covered.

How geography and sales fit together

This study is helpful to all operators who want to identify the exact size of their target audience at a specific geographic location. Animal Stem Cell Therapy Market allows entrepreneurs to determine local markets for business expansion. This study answers the questions below:

1. Where do the requirements come from?2. Where do non-potential customers reside?3. What is the buying behavior of customers in a specific region?4. What is the spending power of the customers in a particular region?

** Enquire for customization in Report @ https://www.stratagemmarketinsights.com/quiry/11599

Having our reviews and subscribing our report will help you solve the subsequent issues:

*Uncertainty about the future: Our research and insights help our customers predict the upcoming revenue pockets and growth areas. This will guide customers to invest their resources.

*Understanding market sentiments: It is very important to have a fair understanding of market sentiment for your strategy. Our insights will help you see every single eye on market sentiment. We maintain this analysis by working with key opinion leaders on the value chain of each industry we track.

*Understanding the most reliable investment center: Our research evaluates investment centers in the market, taking into account future demand, profits, and returns. Clients can focus on the most prestigious investment centers through market research.

*Evaluating potential business partners: Our research and insights help our clients in identifying compatible business partners.

Furthermore, the years considered for the study are as follows:

Historical year 2013-2018Base year 2018Forecast period** 2019 to 2026 [** unless otherwise stated]

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What Will Be The Growth of Animal Stem Cell Therapy Market? Dagoretti News - Dagoretti News

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Meet the Culprits of Cell Culture Contamination – Technology Networks

January 23rd, 2020 11:44 pm

The air is warm and humid, there is an abundance of food, and your friends come and go with their shiny toys. What sounds like a dreamy summer holiday is also the reality of in vitro cell culture experiments, and a golden opportunity for contaminants to intrude. Every person, reagent, and piece of equipment in the laboratory is a potential vehicle for invasive microbes, unwelcome cells and chemical impurities, which can create costly issues in both bench research and manufacturing. Cell culture contamination is a problem on many levels, creating immediate implications for experiments and wider issues for the scientific community.Consequences of cell culture contaminationContaminants can affect all cell characteristics (e.g. growth, metabolism, and morphology) and contribute to unreliable or erroneous experimental results. Cell culture contamination will likely create a need for experiments to be repeated, resulting in frustrating time delays and costly reagent wastage. Data derived from undetected contaminated cultures can end up published in scientific journals, allowing others to build hypotheses from dubious results. The pervasiveness of cross-contaminated and misidentified cell lines is a decades-long issue; in 1967, cell lines thought to be derived from various tissues were shown to be HeLa cells, a human cervical adenocarcinoma cell line.1 However, studies involving these misidentified cell lines continued to feature in hundreds of citations during the early 2000s.2This pattern is a well-acknowledged problem and threatens to undermine scientific integrity. The first published retraction in Nature Methods was due to cell line contamination3, and one conservative estimate of contaminated literature in 2017 found 32,755 articles reporting on research with misidentified cells.4 While many scientists may have been blissfully ignorant in the past, awareness of misidentified cell lines is growing.Deciding how best to deal with this knowledge is not straightforward and has been discussed extensively.4 In the interest of preventing further data contamination, a certificate of authentication of the origin and identity of human cells is now required by the International Journal of Cancer, and encouraged by funding agencies. Others have questioned whether mandatory testing really is the best way forward.3But what should be done about existing contaminated literature? Mass retraction of affected articles may disproportionately punish the careers of a few scientists, and could be a waste of resources containing potentially valuable data. One recently proposed system of self-retraction recommends replacing blame with praise in order to encourage self-correction.5 Post hoc labeling of published articles in the form of an expression of concern allows existing findings to remain accessible, while giving readers a chance to form their own judgement.

Lastly, pathogens carried by cells (either intentionally or accidentally) or in components of the culture medium are potential health hazards, and laboratory-acquired viral infections have been reported.6-8 Indeed, the stakes are higher when cells are to be introduced into patients, highlighting the critical importance of quality control in cell therapies.

While pipetting is a key part of everyday laboratory work, it is also one of the stages most prone to contamination. As sample contamination can affect the reliability of results, it is important to know how it can be avoided, saving both time and money. Download this poster for ten tips to avoiding contamination in pipetting.

Avoid leaving your cultures out of the incubator for extended periods

Label all cultures clearly and unambiguously

Disinfect work surfaces before and after use

Check disinfectants are effective and appropriate choices for the job

Work with only one cell culture at a time

Use separate media and reagents for each individual cell line

Quarantine new cell lines until tested negative for mycoplasma

Avoid overusing and relying on antibiotics

Record how long a cell line has been kept in cultureThe design of the laboratory can also play a role; cabinets should be placed away from through-traffic, doors and air-conditioning inlets.6 Restricting area access to allow only essential laboratory personnel to enter reduces disturbances of airflow around the microbiological safety cabinet.

Water baths, CO2 incubators, shelves and water pans are common culprits and should be cleaned or autoclaved regularly, using a chemical disinfectant where appropriate. Other routes of infection include accidental spillages, contact with non-sterile surfaces, splash-back from pipetting or pouring, microscopic aerosol, and infestation by vertebrates, dust and mites.Research groups isolating stem cells use unique cell properties to filter out undesired cells, explains Dr Mei-Ju Hsu, postdoctoral researcher in stem cell therapy at Leipzig University. Dr Hsu notes that: one of the most important features of mesenchymal stem cells is the attachment and growth on the plastic surfaces without prior coating. This step serves as a good way to eliminate the non-adherent cells (e.g. blood cells) by the removal of supernatants.

Mycoplasma is one of the most common cell culture contaminants, with six species of mycoplasma accounting for 95% of all contamination. Therefore, it is important to improve our understanding of where mycoplasma contamination can stem from and how best to prevent it. Download this infographic to discover more about mycoplasma contamination in cell culture labs.

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Meet the Culprits of Cell Culture Contamination - Technology Networks

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