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Psoriatic Arthritis Treatment Market Advance Technology And New Innovations 2020 To 2025 -Eli Lilly, Roche, Merck, Novartis – Market Research Sheets

January 3rd, 2020 9:48 pm

The report titled Global Psoriatic Arthritis Treatment Market Size, Status and Forecast 2019-2025 provide (6 Year Forecast 2019-2025)enhanced on worldwide competition by topmost prime companies (Eli Lilly, Roche, Merck, Novartis, Abbvie, Amgen, Bristol Myers Squibb, Celgene Corporation, Janssen, Valeant Pharmaceuticals) which providing information such asCompany Profiles, Capacity, Gross, Gross Margin, Product Picture and Specification, Production, Price, Cost, Revenueand contact information. This Psoriatic Arthritis Treatment market report crucial insights that facilitate theMarket Trends, Drivers, Market Dynamics, Overview, Scope, Definitions, Classifications, Opportunities, Competitive Landscape. The report provides key statistics on the market status of the Psoriatic Arthritis Treatment market manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.

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Kits Reagents Instruments

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Hospitals Clinics Ambulatory Surgery Centers Diagnostic Laboratories

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What is the (North America, South America, Europe, Africa, Middle East, Asia, China, Japan) production, production value, consumption, consumption value, import and export of Psoriatic Arthritis Treatment market?

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Economic impact on Psoriatic Arthritis Treatment industry and development trend of Psoriatic Arthritis Treatment industry.

What will the Psoriatic Arthritis Treatment market size and the growth rate be in 2025?

What are the key market trends impacting the growth of the Psoriatic Arthritis Treatment market?

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Development and validation of a clinical rule for recognition of early inflammatory arthritis. – DocWire News

January 3rd, 2020 9:48 pm

This article was originally published here

Development and validation of a clinical rule for recognition of early inflammatory arthritis.

BMJ Open. 2019 02 22;8(11):e023552

Authors: Ten Brinck RM, van Dijk BT, van Steenbergen HW, le Cessie S, Numans ME, Hider SL, Mallen C, van der Helm-van Mil A

AbstractOBJECTIVES: National and international guidelines recommend prompt referral of patients presenting with inflammatory arthritis (IA), but general practitioners (GPs) feel uncertain in their proficiency to detect synovitis through joint examination, the method of choice to identify IA. Our objective was to develop and validate a rule composed of clinical characteristics to assist GPs and other physicians in identifying IA when in doubt.DESIGN: Split-sample derivation and validation study.SETTING: The Leiden Early Arthritis Recognition Clinic (EARC), a screening clinic for patients in whom GPs suspected but were unsure of the presence of IA.PARTICIPANTS: 1288 consecutive patients visiting the EARC.PRIMARY AND SECONDARY OUTCOME MEASURES: Associations of clinical characteristics with presence of IA were determined using logistic regression in 644 patients, while validating the results in the other 644 patients (split-sample validation). To facilitate application in clinical practice, a simplified rule (with scores ranging from 0 to 7.5) was derived and validated.RESULTS: IA was identified by a rheumatologist in 41% of patients. In univariable analysis, male gender, age 60 years, symptom duration <6 weeks, morning stiffness >60min, a low number of painful joints (1-3 joints), presence of patient-reported joint swelling and difficulty with making a fist were associated with IA in the derivation data set. Using multivariable analysis, a simplified rule consisting of these seven items was derived and validated, yielding an area under the receiver operator characteristic curve (AUC) of 0.74 (95% CI 0.70 to 0.78) in the derivation data set. Validation yielded an AUC of 0.71 (95% CI 0.67 to 0.75). Finally, the model was repeated to study predicted probabilities with a lower prevalence of inflammatory arthritis to simulate performance in primary care settings.CONCLUSIONS: Our rule, composed of clinical parameters, had reasonable discriminative ability for IA and could assist physicians in decision-making in patients with suspected IA, increasing appropriateness of healthcare utilisation.

PMID: 30798292 [PubMed indexed for MEDLINE]

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SARS can cause arthritis and gout – The Saxon

January 3rd, 2020 9:48 pm

Few people know that the seasonal SARS hides more dangers than it seems. Incorrect or incomplete treatment of the common cold can affect the human body severe pain with every movement because of the infection of the joints.

Getting arthritis or gout possible due to seasonal and SARS, which often suffer from fall and winter. The common cold will develop into pain and deformity of the joints, if you just ignore it or MIS treated. Its all in the bloodstream, which carries the infection throughout the body from the affected areas. Weakened by the struggle with a cold, the immune system literally can miss the infection of the joints, especially if the person recently stood in the cold or got hypothermia.

To lose joints possible not only after you sneeze or cough, but promiscuous sex and urinary tract infection. The infection acts on the same principle that SARS travels through the bloodstream and infects cartilage, bringing the man down. Such rogue infection develops reactive arthritis, a dangerous disease that is very difficult to diagnose.

Under threat and people in the reverse situation, when the immune system is working at 120% because of the medicine. He can be overzealous after the suppression of the disease, and begin to attack the cartilage of joints, causing rheumatoid arthritis. The disease quickly immobilizes a joint and switched on the nearby tissue, which is extremely dangerous.

The main danger of such a receiving arthritis in that it is extremely difficult to diagnose and successfully cure it is possible only at the initial stage (both diseases). Because doctors do not advise to delay going to the hospital, or instead of therapy and pills, the patient will have to lie on the operating table and undergo a long rehabilitation.

Maria Batterburyis a general assignment reporter at the Saxon. She has covered sports, entertainment and many other beats in her journalism career, and has lived in Manhattan for more than 8 years. Vivian has appeared periodically on national television shows and has been published in (among others) NPR, Politico, The Atlantic, Harpers, Wired.com, Vice and Salon.com..

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The Silent Thief: Glaucoma can steal your sight, but vision loss is preventable. – The Burg News

January 3rd, 2020 9:47 pm

Glaucoma is the leading cause of irreversible blindness in the world and the United States.

The number of people with glaucoma worldwide is estimated to be over 70 million and is expected to increase to over 110 million by 2040. It currently affects more than 3 million people in the United States and is the leading cause of blindness in both African American and Hispanic populations. This is despite the fact of a low overall prevalence of 3.5 percent.

Glaucoma belongs to a class of eye diseases known as optic neuropathy. There are two main types of glaucoma: open angle and narrow or closed angle. The angle is the opening where the fluid drains from the eye. In narrow angle, the channel is blocked and the fluid cant exit. With open angle, the channel is not obstructed. In the western world, 90 percent of glaucoma is of the open angle type.

Vision loss is caused by progressive damage to the optic nerve. The eye is similar to a video camera. It is connected to the vision center in the brain by a cable that is called the optic nerve. The nerve is a bundle of about 1 to 1.5 million nerve fibers. In glaucoma, for a reason we still do not fully understand, these fibers begin to die off. Without proper treatment, the number of fibers will continue decline and, with that, the patients vision.

It used to be thought that the loss of nerve fibers was the result of a high pressure inside the eye. Studies have shown that damage can actually occur at normal or even low pressures. Current thinking is that an elevated pressure is a risk factor for glaucoma but not the disease itself. As it is the only risk factor that can be treated, all current treatment of glaucoma involves lowering the eye pressure. This can be achieved by using topical medication (drops), laser therapy, surgery or a combination of treatments. Successful treatment will lower the pressure to the point that no further nerve fibers and, hence, vision will be lost.

There are three main reasons why people go blind from this disease. First, they are not diagnosed. Recent studies have estimated about 1 million people in the United States with glaucoma are currently undiagnosed. Although many factors are involved here, the two main culprits are lack of symptoms until very late in the disease and failure to routinely have a thorough eye examination.

The second reason is that patients are notoriously non-compliant with their therapy. There have been many papers, articles and even YouTube videos about this. But the bottom line is thisno treatment is effective if it is not used.

Finally, treatment has to be sufficient to slow or stop disease progression. If therapy is inadequate, the benefit of accurate diagnosis and compliance will suffer.

Glaucoma can be diagnosed at any age, but is more common after the age of 40. Vision loss is completely preventable with early diagnosis and proper treatment. This cannot happen without routine eye examinations. A minimum examination would consist of a measurement of eye pressure and a dilated stereoscopic evaluation of the optic nerve. If there is evidence of increased risk, a more detailed investigation would include formal test of the visual field and optic nerve imaging.

Rememberglaucoma is known as the silent thief of sight as there are no symptoms until late in the disease. If you are over 40, have a family history of glaucoma or any other risk factors, make sure to have your eyes examined regularly.

Dr. John J. ODonnell Jr. is an optometrist with Premier Eye Care Group. For more information, visitwww.premiereyes.com.

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Woster: 2020, good eyesight or a new year? – The Daily Republic

January 3rd, 2020 9:47 pm

Lets face it. Doesnt the year 2020 make you think of 20/20, supposedly the description of ideal vision? Were entering a year that sounds more like something youd hear during a visit to the optometrist than the vision of whole new worlds of opportunities just over the next hill.

The fact that I can see a written 2020 at all is probably thanks to my first-grade teacher, Fern Bairey. I assume she was the one who noticed that I couldnt see the blackboard in her classroom. I got my first set of eyeglasses shortly after entering her classroom in Reliance. Until then, I didnt know a kid was supposed to see the shapes of tree leaves and the tassels on the ears of corn in the fields.

I had a cowlick and a round face, so when I got my eyeglasses, I looked like Ralphie, the kid in A Christmas Story. Classmates made fun of me, naturally. It was only years later that I saw a billboard with a glasses-wearing kid who looked like first-grade me. The slogan said, Dont laugh. Now he can see. I wish Id seen that back in Reliance.

Ive worn glasses since Miss Baireys class. My optometrists told me years ago my vision was, lousy and likely to get worse. It did. Last time I checked, my vision was about 20/200 in one eye and 20/400 in the other. I got my first pair of contact lenses when I entered college, and Ive worn those ever since, although I generally switched back to glasses when I had to work around wheat chaff or corral dust during college summers on the farm.

One of my craziest experiences with contact lenses came at the end of my senior year in college when I was considering a career in the U.S. Air Force. Along with a whole bunch of other young men who had been told they could write their own ticket if they enlisted for a four-year-hitch, I went through the physical exam process in Sioux Falls, at the Post Office building, I think it was. The impatient Air Force guy hustled us through the line so quickly that when he barked at me to put your eyes to the scope and read the letters, I did it without mentioning my contact lenses. Imagine my surprise when they rated me 20/30 and good to go for training as a navigator.

As is often the case, the loud, impatient guy whose yelling helped create the problem wasnt the one who had to listen as I explained that my vision really was 20/400, that it probably hadnt been anywhere close to 20/30 even when I left the Mitchell hospital in January of 1944 and that the mix-up, if truth be told, happened because the mean guy didnt give me a chance to tell him about my contacts.

The episode kind of soured me on a career in the Air Force writing news releases for home-town newspapers about the activities of their service members. (The first time I talked with the on-campus Air Force recruiter in the spring of 1966, he asked me my major. When I said journalism, he told me there was more than a good chance that if I enlisted after graduation, Id spent my military career at a base somewhere in Texas writing those home-town news blurbs. That didnt sound so bad to me, although Texas?) After the contact lens incident, I never got the impression that the Air Force was sorry to see me miss out on the chance to don a uniform with the blue from the skies and a pretty girls eyes and a touch of Old Glorys hue, as the song goes.

In the interests of full disclosure: The Air Force sent me to a psychiatrist because, when asked, I said I sometimes had difficulty sleeping. Theyd probably have been money ahead if theyd sent me to an optometrist.

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Grupo Antolin and Eyesight Technologies team up to provide intelligent in-cabin monitoring solutions – Automotive World

January 3rd, 2020 9:47 pm

Eyesight Technologies, a leading provider of computer vision AI solutions for the in-car automotive industry, and Grupo Antolin, one of the largest manufacturers of vehicle interiors in the world, announced today that the companies have entered into a partnership to provide driver and occupancy monitoring solutions to OEMs worldwide.

Grupo Antolins ability to integrate 3rd party solutions into its car interior components and the development of their control electronics will be paired with Eyesight Technologies advanced in-cabin sensing solutions (Driver Sense and Cabin Sense) to deliver smart-integrated interior systems with great added value.

The collaboration will provide car manufacturers with in-cabin sensing solutions tailored to answer regulatory needs and enhance the driving & riding experience, leveraging Eyesight Technologies computer vision AI and Grupo Antolins interior component design and integration capabilities.

Eyesight Technologies solutions encompass a variety of applications related to driver and passenger safety and experience inside the vehicle. Eyesight Technologies Driver Sense, driver monitoring system, tracks the drivers eyes, eyelids, pupils, head pose, and gaze to determine the alertness, wakefulness, and attentiveness of the driver. The companys Cabin Sense, occupancy monitoring system, monitors the cars interior, including passengers, to power adaptive safety features, and a personalized in-car environment. Driver identification and action detection such as smoking, wearing seatbelt and holding a phone are also available as part of Eyesight Technologies solutions.

SOURCE: Eyesight Technologies

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2020 vision for all of us – The Hutchinson News

January 3rd, 2020 9:47 pm

And so begins a new year. It rolls by on a fairly annual basis, but each time, I feel quite unprepared to make the switch. Awkwardly, the other day I wrote 2016 on something; I guess if Im going to be behind the times, I might as well go for it.

Im thinking, though, that 2020 has a nice enough ring that Ill get the hang of it quicker. Well see what happens.

Chinese culture attributes a certain animal to each calendar year, rotating through a set of 12 options ranging from rabbits to tigers. 2020 would be the Year of the Rat, but I had enough experience with rats in Kenya and Im not really into them.

Since vegetables are more down my alley, Ive decided to make an executive decision and deem 2020 the Year of the Carrot!

It makes perfect sense to me 20/20 means you have pretty good vision, and what vegetable is classically associated with good vision? Carrots, of course.

My logic starts to break down immediately when I explain that much of that belief is based on urban myth. The well-perpetuated notion that carrots can help you see in the dark, and drastically improve your eyesight in general, is actually due to World War II propaganda. In order to disguise new radar technology, the British army praised carrots as their secret weapon in obtaining night vision.

I guess their ploy worked because weve been believing it ever since.

To be fair, carrots definitely arent bad for your eyes. They are such great sources of vitamin As precursor, beta carotene that, yes, it is named after them. Vitamin A can at least help maintain good vision, and severe deficiency can contribute to loss of eyesight.

But carrots arent the winning sources of vitamin A: liver products can have up to over ten times the amount of carrots. Sweet potatoes, winter squash, and even hearty greens can all be denser vegetable sources than carrots.

On a similar note, although we typically refer to 20/20 as perfect vision, it isnt. It denotes normal visual acuity, but 20/15 or even 20/10 would be much better, as it means you can see with clarity things 20 feet away that 20/20 people can only see closer at 10 feet away.

All that said, I still choose carrots because I love them so much. Besides, I dont plan on advocating a Year of Liver any time soon.

And I still think vision is good to consider at the beginning of this new year. In the coming months, what will you be looking for? Are your eyes open to daily blessings? Are you really seeing the people around you?

So go ahead and make black-eyed peas or cornbread for New Years if you want; go ahead and make New Years resolutions if you want. But just make sure you make carrots, too.

Amanda Miller writes a column about local foods for The Hutchinson News. She teaches classes at Apron Strings and makes cheese on her familys dairy farm near Pleasantview. Reach her at hyperpeanutbutter@gmail.com

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20/20 vision in 2020: Name and claim small business success – USA TODAY

January 3rd, 2020 9:47 pm

Rhonda Abrams, Special to USA TODAY Published 8:00 a.m. ET Jan. 1, 2020

Happy New Year and welcome to the year of20/20 Vision for Success in your small business.When someone has 20/20 vision, it means they have excellent eyesight.Solets make 2020 the year you can clearly see success ahead.

Youll need:

One of Rhondas Rules is You cant reach a goal you havent set. In other words, you have to identifythe goals you want to reach in the next 12 months. What do you want your business to become? What is your definition of success?I rarely quote the Bible in my column, but I would remind you of Proverbs 29:18 Where there is no vision, the people perish.

The same is true in business. When you dont have a clear and sensible vision for what you want to achieve, then your business will perish.

(Photo: GETTY IMAGES)

20/20 Vision: I want you to have a really defined vision for your small business in 2020. This is more than just a vague sense of what youd love to achieve (I want to be famous. I want to be the most successful realtor on the West Side. I want to have a really successful app.). But for 20/20 vision, you need to both name and quantify your goal. (I want to launch my water use tracking app by June and get 900 users by the end of the year.)

You cant just setgoals,you need a roadmap on how to best reach those goals. Whattasks must you accomplish to reach those goals?Whatresourceswillyou needmoney, personnel?What steps are crucial? What activities should you put aside until next year?

More: Small-business owners need policies, strategy to keep the workplace safe

More: Start 2020 off right: Take 6 smart small-business steps before the end of the year

More: Looking for a small-business role model? Check out these celebrity entrepreneurs

20/20 Vision:You need a business plan.Sosit down in early January and begin working on it create both a long-term business plan and an annual plan.I believe in this so much that I wrote the book on it:Successful Business Plan: Secrets & Strategies.

If you want something to thrive, you have to focus your attention on it. One of the most difficult challenges for small business owners is they must take care of so many competing tasks that its difficult to stay focused. In 2020, be sure toidentify the tasks that aretruly most importantto achieveyour definition of success. Make sure youfocus on thoseeven as you have to tend to day-to-day tasks.

20/20 Vision:Find yourself a good organizing tool one that works for you. It may be a software program like Trello(I just used that to manage my entire kitchen remodel) or Monday. Oryou may like to see your priorities and tasks written out on paper. My friend swears by Bullet Journaland I use a simple spiral bound notebook that is always with me.

Your business doesnt operate in a vacuum. You need to see whats going on in your industry, with your competition, with your target market.

20/20 Vision:Join an industry trade group. Subscribe to industry newsletters, listen to industry podcasts. Visit your competitors websites regularly. And read trustworthy news outlets that rely on facts.

You need to make sure you pay attention to the details of your business, not just the big picture. In particular, keep a close eye on your financial situation. Find ways and choose tools that keep your eye on your financial resources and your bottom line.

20/20 Vision:Automate as many payments as you can so theyre always made on time. Download mobile apps you have available from your accounting software programs, banks, credit cards, so you can easily and regularly check on your finances. Monitor how you send out invoices, deposit payments, pay bills so you make sure your internal processes are both safe and streamlined.

Together lets see howwe can make 2020 the best year ever.

Rhonda Abrams is the author of "Successful BusinessPlan: Secrets& Strategies," the best-selling business plan guide in the US, just released in its seventh edition.Connect with Rhonda on Facebook, and Twitter and Instagram: @RhondaAbrams. Register for Rhondas free business tips newsletter at http://www.PlanningShop.com.

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Do you have 2020 vision? – Mount Airy News

January 3rd, 2020 9:47 pm

George Randall Jr.

It seems like just yesterday the calendar flipped over to the year 2000, and many were concerned about the Y2K problem; wondering if all our computers, and everything linked to them would crash. I remember certain radio (false) prophets telling everyone to go stockpile food for the end of civilization, as we know it. All that worrying for nothing.

Now here we are at the New Year 2020. God is still Almighty, and everything is still under His authority and power. He is still good and faithful to provide, protect, and give His peace to each one who trusts in Him, each day we continue here on Planet Earth. We can still trust Him with our lives.

Please receive and meditate on each Scripture. Matthew 6:25-34, Therefore I say unto you, Take no thought for your life, what ye shall eat, or what ye shall drink; nor yet for your body, what ye shall put on. Is not the life more than food, and the body than raiment? Behold (look at intently, take notice, observe and consider carefully) the birds of the air: for they sow not, neither do they reap, nor gather (their crops) into barns; yet your Heavenly Father feeds them. Are ye not much better than they? If God so clothe the grass of the fieldshall He not much more clothe you, O ye of little faith? Therefore (because of this great assuring truth) take no thought, saying, what shall we eat or, what shall we drink? But seek ye first the Kingdom of God, and His righteousness; and all these things shall be added unto you.

Do you have 2020 vision? One of my three darling daughters works in an eye doctors office where I am also a patient. Ive been told that perfect vision for a human being is 20/20. We are now in the year 2020, and I wonder what we might see this year. I hope my friend, that our eyes will be open to the Word of God, and to the work of God. I hope we will have a clear vision for lost souls who need Jesus in this broken world. I hope we see the talents God has given us to lovingly invest in people for His Kingdom.

Is your heart available for Gods Spirit to move through, to accomplish His will and purpose? Will you lift up Jesus in witness and worship so all people will see Him, and many believe on Him? Are your spiritual eyes open? Proverbs 29:18 states, Where there is no vision, the people perish. Souls are perishing; some are dying without any clear sight of the Savior. Perhaps they would see the Savior, Jesus Christ if we would proclaim Him more boldly, and display Him more faithfully in our lives, fellow Christian. (John 4:35, lift up your eyes and look) Perhaps the lost would look deeper into the satisfying of their spiritual need if we would kindly share with them our relationship with our LORD. Is our relationship with the LORD where it should be? If not, each day is a new day. Start over!

Exodus 20:20, And Moses said unto the people, Fear not: for God is come to prove you, and that His fear may be before your faces, that ye sin not.

First notice the location of this verse; its 20:20. I believe thats no coincidence. Even though there were no verses marked in the original Hebrew, consider Gods divine inspiration over the complete translation of His Word into the English Language, circa 1535-1560. Consider the position of this verse, and its powerful content. I believe there is a great revelation here for us to see with eyes wide open and attentive. Its about clear 20/20 vision.

Is His fear before your face, before your eyes? Do we fear God to the point of turning away from sin and its dire consequences? Do we love Him enough to embrace His righteousness, to be His children of light? I believe this will be a year for God to prove us. Websters 1828 Dictionary defines prove as, to try; to examine; to ascertain some unknown quality by an experiment, test or standard.

When we are put to the test, will we wholeheartedly rely on our Heavenly Father by faith? Will we come forth refined as silver and gold? Will we ask our Father to fill us with His Holy Spirit, to guide and rule our lives? Will we choose His Kingdom over serving self, and the vain things of this corrupt world? May our answer be yes Lord.

We are at another point of decision, at another opportunity to take the high road. Let us accept Gods mission to be agents of compassion toward desperate, but precious souls, and, may we be ambassadors of the Gospel message. In Gods Word is supernatural life changing spiritual power over darkness. Have 20/20 vision my friend. My prayer; Dear Father, In this new year of 2020, may Your Kingdom come, Your will be done in Earth, and in us as it is in Heaven; because, Yours is the kingdom and the power and the glory for ever and ever. Amen.

George Randall Jr.

George Randall Jr. is the minister to youth at Rocky Ford Christian Church in Cana, Virginia.

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Unhealthy food could badly impact eyesight: Study – The Indian Express

January 3rd, 2020 9:47 pm

By: Lifestyle Desk | New Delhi | Published: January 2, 2020 3:20:27 pm Unhealthy food, old age eyesight, red meat, fried foods, high-fat dairy. (Source: Getty/Thinkstock Images)

Keep an eye on what you eat, as a recent study has found a link between an unhealthy diet and vision loss at an older age. After researching for around two decades, results have shown that a diet rich in red meat, fried foods, high-fat dairy, processed meats and refined grains can badly impact eyesight. The study, published in the British Journal of Ophthalmology, says there are links between a diet rich in unhealthy foods and age-related macular degeneration.

The condition that impacts the retina with age, blurs central vision that is required to see objects clearly and perform everyday activities such as reading and driving. According to the Centers for Disease Control and Prevention (CDC), in the United States, around 1.8 million people aged 40 and above are living with AMD, and another 7.3 million have a condition called drusen, which usually precedes AMD.

Senior study author Dr Amy Millen, of the University at Buffalo in New York, told Medical News Today, Most people understand that diet influences cardiovascular disease risk and obesity; however, Im not sure the public thinks about whether or not diet influences ones risk of vision loss later in life. We wanted to examine how the overall pattern of ones diet may predict later development of AMD, both early-onset and late-stage disease. What we observed in this study was that people who had no AMD or early AMD at the start of our study, and reported frequently consuming unhealthful foods, were more likely to develop vision-threatening, late-stage disease approximately 18 years later.

The study looked at 66 different food types, which they later categorised into prudent, which included healthy food and western, which includes processed, red meat, fried stuff, etc. Although the researchers found no link between early AMD and dietary patterns, they found that the incidence of late AMD was three times higher among those with a Western diet pattern.

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Faith Works: You might be surprised by what you see – The Newark Advocate

January 3rd, 2020 9:47 pm

Jeff Gill, Guest Columnist Published 4:00 p.m. ET Jan. 3, 2020

How many ways have we seen 2020 as a year conflated with 20/20 as a measure of vision?

I was in seminary when I first heard reference to goals and planning towards the year now begun, mixing up the usual metric for clear vision with the Anno Domini, Year of Our Lord Two thousand and twenty.

And I hate to tell you, but it was 35 years ago.

Thats almost four decades of beating that metaphor into the ground, and its with a measure of relief I mark not just having lived to this date, but seeing it start to move past us. No more 20/20 riffs or reminders or relationships.

Im not a person with 20/20 vision. Ive worn glasses since third grade and probably needed them earlier than that. Im about 20/60 in one eye and 20/200 in the other.

What that means in everyday terms is that what the normal person can see at 200 feet of, say, a set of letters on a poster, I can only see at 20 feet. 20/20 vision just means that you see at 20 feet of distance what most people see from 20 feet away. Thats why a person with truly acute vision might have 20/15 vision, because they can see at 20 foot range what the basically enabled watcher would need to step five feet closer to make out.

Which is where I think the idea of labeling a visioning process for a church or any other faith community as 20/20 vision is not a sign of acuity or excellence, but youre actually asking for the average, the generally accepted. And is that the kind of vision we want in our spiritual insight?

Id hope, as a congregation, that my church members would ask and pray and work for a measure of vision that is better than the run-of-the-mill eyesight. Certainly, we dont want worse, and Im glad to have my own corrective lenses to get me roughly back up to 20/20, but our hopes for vision and anticipation should be more for . . . well, how do they measure telescopes or microscopes?

So, to see well into the future, we might want to aspire to 28x vision like a good home telescope, or for insight 100x magnification akin to a desktop microscope. Thats the kind of vision worth pursuing, dont you think?

Anyhow, 20/20 is dead-on average, and while thats useful and common, I think the year 2020 is a good time to retire that image, and maybe even rethink the whole concept of vision statements. Mission statements have been boiled down to a phrase or short set of words for quite a while now; you dont see long mission statements as a standard quote line on either business or non-profit documents very often anymore. Its not to be the leader in every market we serve, to the benefit of our customers and our shareholders or a company that builds value for its shareholders through its employees by creating an atmosphere of optimism, teamwork, creativity, resourcefulness and by dealing with everyone in an open and ethical manner. Now, youre more likely to see Peace of mind or To inspire humanity.

A vision statement should state the goal youre working together to achieve, and a mission statement your particular part of making progress towards that vision. My own congregation filed a very forward looking vision statement with the Ohio secretary of state back in 1891: To glorify God and better humanity. While we have a more recent and much longer mission statement, we work with a simplified condensation of it as Worship, Serve, Grow. Those three words offer a visitor or guest our sense of how our church is participating in that larger vision to glorify God and better humanity through the values of corporate worship, shared service, and a commitment to personal growth in spiritual maturity.

How does your church community envision the goal youre together to support? And what are you particularly called and gifted to accomplish in that pursuit as a local church? Im betting you can do better than an average, common, 20/20 vision of those ends.

Jeff Gill is a writer, storyteller, and pastor in Licking County; tell him how youre thinking about vision atknapsack77@gmail.com, or follow @Knapsack on Twitter.

Read or Share this story: https://www.newarkadvocate.com/story/opinion/2020/01/03/faith-works-you-might-surprised-what-you-see/2794032001/

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Brain Can Combine Natural And Artificial Vision To Help Treat Common Form Of Blindness – Eurasia Review

January 3rd, 2020 9:47 pm

Macular degeneration (AMD) causes blindness in millions of people in the Western world. It is the most common cause of severe vision loss in the Western world among those aged 50 and over, and its prevalence increases with age. Though there is no cure for AMD, significant recent advancements in artificial retina implants may lead to effective treatment.

Located inside the eye the retina contains light receptors (photoreceptors) which absorb light. Information is then processed and transmitted to the brain. The macula, the central area of the retina, processes most of the information that reaches the brain from the eye, enabling one to see while reading and driving, facial recognition, and any other activity that requires accurate vision.

In the peripheral retina, the area of the retina outside the macula that assists mainly with spatial judgment, vision is 10-20 times less precise. In AMD precise vision is impaired due to damage to the center of the retina, while peripheral vision remains normal.

When there is damage to the photoreceptor layers in the retina, an artificial retina a device built from tiny electrodes smaller in width than a hair may be implanted. Activating these electrodes results in electrical stimulation of the remaining retinal cells and results in visual restoration, albeit partially.

AMD patients implanted with an artificial retina possess a combination of artificial central vision and normal peripheral vision. This combination of artificial and natural vision is important to study in order to understand how to help the blind. One of the critical questions in this regard is whether the brain can integrate artificial and natural vision properly.

In a new study published in the journalCurrent Biology, researchers from Bar-Ilan University and Stanford University report for the first time the discovery of evidence indicating that the brain knows how to integrate natural and artificial vision, while maintaining processing information that is important for vision.

We used a unique projection system which stimulated either natural vision, artificial vision or a combination of natural and artificial vision, while simultaneously recording the cortical responses in rodents implanted with a subretinal implant, said Tamar Arens-Arad, who conducted the experiments as part of her doctoral studies.

The implant is composed of dozens of tiny solar cells and electrodes, developed by Prof. Daniel Palanker at Stanford University.

These pioneering results have implications for better restoration of sight in AMD patients implanted with retinal prosthetic devices and support our hypothesis that prosthetic and natural vision can be integrated in the brain. The results could also have implications for future brain-machine interface applications where artificial and natural processes co-exist, said Prof. Yossi Mandel, Head of Bar-Ilan Universitys Ophthalmic Science and Engineering Lab and the studys lead author.

The research was carried out in Prof. Mandels lab at the School of Optometry and Vision Science, Mina and Everard Goodman Faculty of Life Sciences and the Institute of Nanotechnology and Advanced Materials (BINA) at Bar-Ilan Universitys, in collaboration with Prof. Palanker of Stanford University. The study was conducted by Tamar Arens-Arad in collaboration with Dr. Nairouz Farah, Rivkah Lender, Avital Moshkovitz and Thomas Flores.

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Diabetic Neuropathy Market Innovations, And Top Companies Forecast To 2029| Pfizer Inc, Eli Lilly and Company, Actavis Pharma Inc – Neptune Pine

January 3rd, 2020 8:44 am

New York City, NY: Jan 2020 Published via (Wired Release) MarketResearch.Biz adds Diabetic Neuropathy Market report to its research report database. It is a thorough study of vital elements of the markets such as drivers, growth opportunities, challenges, restraints, current and upcoming trends, SWOT analysis, and many more among other market influencers and strategic information. After comprehensively analyzing these market parameters, the information is presented in a very organized manner that clearly mentions the growth prospects of the Diabetic Neuropathy market during the forecast period.

Making you aware of the latest innovations, market developments, challenges, and opportunities those are estimated to propel Diabetic Neuropathy market growth, this research report puts you in a top position and gives a chance to make use of every opportunity and upcoming trend which can be changed into significant revenues. Diabetic Neuropathy market analysis is extensive into given categories and segmentation and the report is presented in a chapter-wise section for easy finding of required details.

For competitor study, it covers all key players and their respective business information for the pervasive understanding of the competitive scenario. It also makes insertion of their business strategies and reveals the recent developments among major players along with the data of any known collaborations between them. In brief, the well-presented competitive landscape makes you understand the degree of competition.

Being a worldwide report, distinct regions have been studied with detail regional analysis of North America, Europe, Asia Pacific, Middle East & Africa, and Latin America. The regional study helps gain insights on the growth of the market in terms of market size, share, and revenue(USD), thereby revealing the market value, volume, and penetration.

For Better Understanding, Request A Free Pdf SampleCopy Of Diabetic Neuropathy Market Here@ https://marketresearch.biz/report/diabetic-neuropathy-market/request-sample

Our FREE SAMPLE COPY of the report gives a brief introduction to the research report outlook, TOC, list of tables and figures, an outlook to key players of the market and comprising key regions.

Competitive Landscape

Global Diabetic Neuropathy market is highly cleft and the key players have used numerous plans such as new product launches, acquisitions, mergers, collaborations, innovation in products, expansions, agreements, joint ventures, and others to increase their footmarks in this market.

Key players profiled in the report include: Actavis Pharma Inc, NeuroMetrix Inc, Astellas Pharma Inc, Meda Pharma GmbH, Eli Lilly and Company, GlaxoSmithKline plc, Pfizer Inc, Cephalon Inc, Johnson & Johnson Inc and Boehringer Ingelheim GmbH

Market Segmentation:

Segmentation on the basis of disorder type: Peripheral neuropathy, Autonomic neuropathy, Proximal neuropathy, Focal neuropathy, Segmentation on the basis of treatment: Radiotherapy, Physiotherapy

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There Are 13 Chapters To Extensively Display The Diabetic Neuropathy Market:

Chapter 1: Global Diabetic Neuropathy Market Outlook, Product Introduction, Market Segmentation, Market Study of Regions, Market Dynamics, Constraints, Opportunities and Industry News and Policies.

Chapter 2: Global Diabetic Neuropathy Market Chain Study, Upstream Raw Material Suppliers, Key Players, Production Process Study, Cost Analysis, Market Channels, and Key Downstream Buyers.

Chapter 3: Value Study, Production, Price Analysis and Growth Rate Of Diabetic Neuropathy Market by Type.

Chapter 4: Downstream Features, Consumption and Diabetic Neuropathy Market Share by Application.

Chapter 5: Production Volume, Gross Margin, Price, and Revenue (USD) of Diabetic Neuropathy by Regions.

Chapter 6: Diabetic Neuropathy Production, Consumption, Import/Export by Regions.

Chapter 7: Diabetic Neuropathy Market Regional Status and SWOT Analysis.

Chapter 8: Global Competitive Landscape, Product Description, Company Profiles, Diabetic Neuropathy Market Distribution Status by Major Players.

Chapter 9: Diabetic Neuropathy Market Study and Projection by Type and Application (2020-2029).

Chapter 10: Worldwide Market Analysis and Forecast by Regions (2020-2029).

Chapter 11: Global Industry Features, Key Growth Factors, New Entrants SWOT Study, Study of Investment Feasibility.

Chapter 12: Market Conclusion of the Complete Report.

Chapter 13: Appendix Such as Research Methodology and Information Resources.

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Leber’s Hereditary Optic Neuropathy, 2019 – Pipeline Review, H2 – ResearchAndMarkets.com – Business Wire

January 3rd, 2020 8:44 am

DUBLIN--(BUSINESS WIRE)--The "Leber's Hereditary Optic Neuropathy (Leber optic atrophy) - Pipeline Review, H2 2019" drug pipelines has been added to ResearchAndMarkets.com's offering.

The Publisher's Pharmaceutical and Healthcare latest pipeline guide Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) - Pipeline Review, H2 2019, provides comprehensive information on the therapeutics under development for Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) (Ophthalmology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) (Ophthalmology) pipeline guide also reviews of key players involved in therapeutic development for Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Phase III, Phase II, Phase I, Preclinical, Discovery and Unknown stages are 1, 1, 3, 2, 7, 2 and 2 respectively. Similarly, the Universities portfolio in Phase III and Phase I stages comprises 1 and 1 molecules, respectively.

Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) (Ophthalmology) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from The Publisher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Scope

Reasons to buy

Key Topics Covered:

Introduction

Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) - Overview

Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) - Therapeutics Development

Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) - Therapeutics Assessment

Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) - Companies Involved in Therapeutics Development

Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) - Drug Profiles

Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) - Dormant Projects

Leber's Hereditary Optic Neuropathy (Leber Optic Atrophy) - Product Development Milestones

Appendix

Companies Mentioned

For more information about this drug pipelines report visit https://www.researchandmarkets.com/r/hp1wmj

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The Longevity Economy: Gigantic And Getting Bigger – Forbes

January 3rd, 2020 8:43 am

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As a new decade and year are about to begin, professional forecasters are, of course, going through the exercise of guesstimating the future course of the markets and U.S. economy. From what Ive seen, theyre generally expecting the record-breaking U.S. expansion to continue at a middling 2% pace in 2020. Among the factors routinely listed as preventing faster growth is the demographics of aging: The rising ranks of retirement-age Americans, many experts say, is bad for the economy.

Theyre wrong. This timeworn economic dictum is not only outdated, it ignores changes in American society that are turning an aging population into more of an economic and social asset than ever. For evidence, take a look at the new report, The Longevity Economic Outlook by the Economist Intelligence Unit for AARP, an update of a 2013 AARP study.

Were still fighting some of the negative stereotypes about older Americans, says Debra Whitman, executive vice president and chief public policy officer at AARP. The Longevity Economy Outlook demonstrates the sheer magnitude of older Americans contributions to all of society.

Also on Forbes:

The new AARP report calculates the contribution to the U.S. economy of the 117.4 million Americans who are 50+ (35% of the population) at $8.3 trillion, or 40% of gross domestic product (GDP). Thats up from $7.1 trillion when AARP last looked in 2013. Put another way, if Americas 50+ population were its own country, its GDP would now be the worlds third largest, following the U.S. and China.

The studys projections to 2050 are equally illuminating, and Ill touch on a few striking figures in a moment. But broadly speaking, the report is a timely reminder that too much of the conversation about aging dwells on costs and burdens of older Americans, while voicing despair at the financing challenges of Social Security and Medicare. The popular image of growing old is too often pictured as years of chronic illness and mental decline as Shakespeare wrote, "sans teeth, sans eyes, sans taste, sans everything."

The Longevity Economic Outlook is just the latest analysis reframing the discussion about aging toward the economic and social possibilities created by greater longevity. The key questions such studies raise are: How can the nation best maximize the economic and social returns from longer, healthier lives? What private and public initiatives would improve the quality of work well into the retirement years, promote lifetime learning and training, boost the odds for successful late-life entrepreneurship and encourage business to imagine products and services geared toward engaged older adults?

While these questions have been floated around for years by reformers, its time to get urgent about embracing change.

Older adults are an increasingly powerful force as workers, consumers, entrepreneurs and active participants in their communities, says Paul Irving, chairman of the Milken Institute Center for the Future of Aging. But an aging population should not be feared. The rapid growth of the longevity economy offers new opportunities for innovation, employment and economic growth for people of all ages.

The recent Washington Innovation in Longevity Summit that my colleague Richard Eisenberg attended was filled with evidence of burgeoning interest by tech entrepreneurs and investors here and abroad to serve the 50+ market. Almost every week, I hear from people from another country saying: I want you to meet an entrepreneur or I have an investment fund for you to look at, said Mary Furlong, host of the summit.

Now, let me turn to the future of 50+ Americans, as the AARP report sees things:

While these gains are expected to be driven by businesses across the board, several fields in particular will do well, according to AARP, including financial services, insurance and health care.

The Economic Intelligence Unit, Bureau of Economic Analysis, REMI

Two other sets of numbers in the report are worth emphasizing and refute conventional wisdom that older Americans are a financial burden on the nation.

The Economist Intelligence Unit, Bureau of Labor Statistics, REMI

First, the tax contribution of the 50+ group is substantial. For example, the study says, the share of federal income taxes paid by the 50+ population amounted to 59% of the total income taxes paid in 2018, far above their share of the population Their portion of the federal tax total in 2050 is projected to rise to 65%. A similar dynamic holds on state and local levels.

The second figure of note is the estimated economic value of unpaid contributions. Those are things like caring for an aging parent, grandparents supporting grandchildren and volunteering. The AARP report puts the total value of this unpaid work at $745 billion in 2018.To put that in context, $745 billion is slightly more than total amount of Medicare benefits paid in 2018.

Perhaps most importantly, especially in an era when memes like OK Boomer manage to get an audience, is the theme of intergenerational benefits in the workplace and in society that runs throughout The Longevity Economic Outlook. Simply put, ideas for improving economic opportunities for older adults also boost prospects for younger generations (who, after all, will age, too).

Want the economy to grow faster than 2%? Then lets start encouraging older Americans to work longer if they can; welcome them into the workplace; treat them with respect and give them the opportunity to use their skills and experience for employers and to start their own businesses.

That will make them become an even more powerful force for rejuvenating the economy.

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The Longevity Economy: Gigantic And Getting Bigger - Forbes

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Tom Brady playing at 42 shows Patriots QBs amazing mental stamina on top of physical longevity, Ben Watson – MassLive.com

January 3rd, 2020 8:43 am

Tom Brady leading the New England Patriots to the playoffs is a physical wonder at age 42. Its clear to anyone watching him suit up week after week. But its especially impressive to the guy with the locker immediately to Bradys right: Ben Watson.

On Thursday, Watson marveled when presented with the fact that Brady would be playing in his 41st career playoff games Saturday

Thats longer than some peoples career," Watson said. Thats amazing. Im sure he would downplay it, but thats special.

When it comes to longevity in the NFL, there are few who can appreciate what Bradys accomplished like Watson, who turned 39 earlier this season.

Brady has been fortunate to stay in the NFL this long, but Watson wants to make it clear: that sort of longevity doesnt happen by accident. Professional football players are often blessed with great genetics, Watson says, but it doesnt mean much without the will to hone that talent into something great on the field.

When it comes to Brady, few have matched the amount of effort put forth to stay in the game.

Hes put in a tremendous amount of work, physically, mentally, emotionally, to be able to keep doing it over and over and over again, Watson said. One people dont understand sometimes is the stress mentally that playing at this level has on you. A lot of guys, sometimes tap out while their bodies can still probably play. But mentally having to turn it on over and over and over again, under pressure, over and over again, for years after years, burns you out. So to have that competitive stamina that he has is really amazing."

Different guys react differently when it comes to the mental aspect of football. Brady is still going strong. But other guys dont stick around quite as long. Rob Gronkowski is the perfect example. The retired tight end has said he could probably still play in the league. However, he admits that he longer has the competitive fire to go back out there.

Watson said its been special to go out and play with a great leader like Brady in a second go-around -- a decade after his first stint in New England.

Hes the leader on this team, the leader of this organization and its going to be a joy for me to go out on the field with him," Watson said.

As the team head to the postseason, we could be facing the final game in a Patriots uniform for both Brady and Watson. Will either player stick around in New England -- or in the NFL? Its hard to tell at this point.

Brady and Watson have bested the test of time so far. But soon enough, the time to hang it up will come.

They say age is a number and thats kind of true, Watson said. But obviously we all have an expiration date -- of our lives in its entirety and also on our careers. But it doesnt mean you cant do great things as you get older in age and as you get outside whatever the norm is for pro sports and I think hes proven that.

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Motivation and visualisation: The keys to Ai Ueda’s longevity – Olympic Channel

January 3rd, 2020 8:43 am

The Japanese triathlete demonstrates her use of mindfulness, visualisation and motivation, in the new Bridgestone Olympic Channel interactive experience.

As well as being a two-time Asian triathlon champion and an Asian Games gold medallist, Ai Ueda knows a thing or two about sports psychology.

Known as the 'Iron Girl' in Japan, she has competed in 200 International Triathlon Union (ITU) competitions, achieving 49 podium finishes and 29 wins.

As part of new Bridgestone Olympic Channel experience Olympic State of Mind, Ueda reveals the tools she uses to perform at her peak.

The goal of Olympic State of Mind is to help people to be the best version of themselves, through interviews with elite sports stars, informative articles, quizzes and interactive games.

Ueda's consistency over such a long career is what truly marks her out from her rivals.

The 36-year-old first competed in elite triathlon in 2003 and remains at the top of her game as she targets a fourth Olympic appearance at Tokyo 2020.

She told Olympic Channel, "I have three main things that act as my sources of motivation. The first one is to have a dream to achieve.

"The second is a smile. Always staying positive and having a smile on your face. The third is not having limits.

"I think if you put limits on yourself you stop yourself from growing to your full potential. For me, having ambition is massively important for personal growth." - Ai Ueda to Olympic Channel.

This season, Ueda defended her title on home soil at the Miyazaki ITU Triathlon World Cup, while also triumphing in Lima, Cape Town and Nur-Sultan.

Another common feature of Ueda's races is her constant ear-to-ear smile.

In a sport where athletes push themselves to their cardiovascular limits and are subject to external factors like the weather, imagining joy helps Ueda find her all-important race rhythm.

She said, "Visualise the joy you'll feel when you make it happen. Then keep a smile on your face in the good times and bad.

"Use that smile to turn the people offering support around you into allies. It's great when you can create this flow together and the people who were with you at each step can share in your victory."

However, it hasn't always been plain sailing for Ueda.

The Kyoto native went without an ITU World Cup win from 2016 to 2018, but came roaring back to the top of the podium through her use of motivation and visualisation.

"The Olympic State of Mind is what transforms you into the best version of yourself. I completely support this." - Ai Ueda to Olympic Channel

"To everyone out there chasing their dreams, I'd like to let you know what I think is important.

"It's probably going to be difficult to achieve your goals if you don't have personal faith in your own potential."

The interactive experience is now live on Olympic Channel.

Keep an eye out for the video clips, articles, quizzes and games for you to watch, read, and play, plus a special episode of the Olympic Channel Podcast.

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Eating in a 6-hour window and fasting for 18 hours might help you live longer – KTVI Fox 2 St. Louis

January 3rd, 2020 8:43 am

File photo

Abstaining from food for 16 to 18 hours a day could be key to treating a variety of health conditions even if youve got to train yourself to push past the hunger.

A review of past animal and human studies in The New England Journal of Medicine suggests that intermittent fasting can reduce blood pressure, aid in weight loss and improve longevity.

The report functions as a road map of sorts for physicians to prescribe fasting as a method of prevention or treatment for obesity, cancer, diabetes and heart disease.

Study author Mark Mattson, a professor of neuroscience at Johns Hopkins University, hones in on two types: Daily time-restricted feeding (eating 6-8 hours a day and fasting for 16-18 hours) and 5:2 intermittent fasting (fasting two days a week, usually capping a fasting day at 500 calories).

The catch? Most Americans dont intermittently fast (the norm is three meals a day plus snacks) and thus physicians are less inclined to consider fasting a solution to a broad range of health conditions, according to the review.

Because the research is relatively new, the report advises physicians to monitor their patients throughout intermittent fasting and gradually increase the duration and frequency of fasting to guide their transition.

Intermittent fasting has been studied in rodents and overweight adults to improve health across the spectrum, though its not clear if those benefits are the result of weight loss.

Alternating between fasting and eating can improve cellular health, Mattson said, most likely by triggering metabolic switching. In metabolic switching, cells use up their fuel stores and convert fat to energy flipping a switch from fat-storing to fat-saving.

Findings on intermittent fasting range in the diets effectiveness, but some studies in animals and humans have linked the practice to longer lives, healthier hearts, and improved cognition.

The article points to the residents of Okinawa, known for their extreme longevity and low-calorie, nutrient-rich diet. Their intermittent fasting might contribute to their life spans and keep obesity at bay, the authors posited.

Intermittent fasting is thought to improve insulin resistance, which can stabilize blood sugar levels. Findings from a small 2018 study found that three men with type 2 diabetes, also known as adult-onset diabetes, were able to stop taking insulin after losing weight from intermittent fasting findings that clash with the widely-held belief that diabetes is incurable.

A previous study (that Mattson co-authored) showed the switch can increase resistance to stress by optimizing brain function and neuroplasticity, or the brains ability to adapt to develop throughout ones life. And older adults who were put on a restricted-calorie diet showed improved verbal memory compared to two other groups who hadnt fasted, a 2009 study found.

Physical function even improved for some patients. A study of young men who fasted every day for 16 hours lost fat and retained muscle while resistance training for two months.

The long-term effects of intermittent fasting require more research that isnt available yet, and the studies that do exist are narrow. The clinical trials focused on overweight young and middle-aged adults, so the benefits and safety cant be generalized to other groups, the authors said.

Another thing: Its a difficult diet to stick to, particularly in the United States, where the concept of three meals a day is so ingrained in our culture that a change in eating patterns often doesnt cross doctors or patients minds, Mattson wrote.

Itll almost definitely leave participants hungry, irritable and less able to concentrate, the study said.

Almost 40% of people who were assigned to a fasting diet dropped out of a 2017 JAMA study one of the drawbacks of intermittent fasting as a weight-loss regimen, Dr. Frank Hu, chairman of the Department of Nutrition at Harvard Universitys T.H. Chan School of Public Health, noted to Harvard Health Publishing.

Its human nature for people to want to reward themselves after doing very hard work, such as exercise or fasting for a long period of time, he said. So there is a danger of indulging in unhealthy dietary habits on non-fasting days.

When the brain is deprived of food, appetite hormones in the hypothalamus, the brains hunger center, are released in a flurry and can trigger overeating.

But Mattson said the pain is temporary.

Patients should be advised that feeling hungry and irritable is common initially and usually passes after two weeks to a month as the body and brain become accustomed to the new habit, he said.

By Scottie Andrew, CNN

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How to live longer: Following this diet has been proven to increase life expectancy – Express

January 3rd, 2020 8:43 am

Long life expectancy can be attributed to healthy eating, research suggests. As a general rule, a healthy, balanced diet should consist of at least five portions of a variety of fruit and vegetables every day. It is also highly recommended to get enough exercise and the recommended amount is at least 150 minutes per week. When it comes to the particular food one should eat, what are five of the best?

The high life expectancy enjoyed in Japan is largely down to the nations healthy diet.

A 2016 study in the British Medical Journal (BMJ) found that Japanese adults who followed the recommended amount regarding food intake had lower rates of mortality than those who didnt.

The population of the island nation has the lowest mortality rates in the world.

In fact, Japanese people are more likely to reach 100 years old than anyone else in the world.

DONT MISS

What to eat on the Japanese diet?

The diet itself is high in certain carbohydrates, vegetables, fruits as well as fish and meat.

Such foods make for a diet low in saturated fats, processed foods and high in carbohydrates gained form both rice and vegetables.

Foods one should adopt include steamed rice, noodles, tofu, fish, natto, seaweed and fresh cooked fruits and vegetables low in added sugars and fats.

The diet may also contain a modest amount of eggs, dairy or meat. Many Japanese also follow a healthy exercise regime which boosts life expectancy too.

What have experts said?

Dr Craig Wilcox said: The Japanese have a low risk of arteriosclerosis and stomach cancer, a very low risk of hormone-dependent cancers, such as breast and prostate cancer.

"They eat three servings of fish a week, on average, with plenty of whole grains, vegetables and soy products too, more tofu and more kombu seaweed than anyone else in the world, as well as squid and octopus, which are rich in taurine that could lower cholesterol and blood pressure."

Link:
How to live longer: Following this diet has been proven to increase life expectancy - Express

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How to live longer: The best diet to increase life expectancy according to new study – Express

January 3rd, 2020 8:43 am

Long life expectancy can be attributed to a persons diet - a healthy, balanced diet has been proven to improve longevity. Experts recommend eating at least five portions of a variety of fruit and vegetables every day, basing meals on higher starchy foods like potatoes, bread and rice, having some dairy or dairy alternatives, eating some protein, choosing unsaturated oils and spreads, and drinking plenty of fluids.

But new research, published this week, has found the times of day a person eats holds the most benefits.

Dr Mark Mattson, a professor of neuroscience at John Hopkins University School of Medicine, in the US, has said intermittent fasting could be part of a healthy lifestyle."

Intermittent fasting diets usually involve daily time-restricted feeding, which narrows eating times to six to eight hours per day and so-called 5:2 intermittent fasting, in which people limit themselves to one moderate-sized meal two days each week.

A range of human and animal studies have shown that alternating between times of fasting and eating supports cellular health, probably by triggering an age-old adaptation to periods of food scarcity called metabolic switching.

READ MORE:Type 2 diabetes symptoms: How often do you go to the toilet? Warning sign of the condition

Such a switch occurs when cells use up their stores of rapidly accessible, sugar-based fuel, and begin converting fat into energy in a slower metabolic process.

Dr Mattson says studies have shown that this switch improves blood sugar regulation, increases resistance to stress and suppresses inflammation.

Because most Americans eat three meals plus snacks each day, they do not experience the switch, or the suggested benefits.

In an article in the New England Journal of Medicine, Dr Mattson said four studies in both animals and people found intermittent fasting also decreased blood pressure, blood lipid levels and resting heart rates.

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Evidence is also mounting that intermittent fasting can cut risk factors associated with obesity and diabetes.

Studies also suggest intermittent fasting could boost brain health too.

Experts say people adopting intermittent fasting regimes should gradually increase the duration and frequency of the fasting periods over the course of several months, instead of "going cold turkey."

Many studies have highlighted the benefits of a vegetarian diet.

The authors of a large, long-term study concluded vegetarianism is associated with a reduced risk of ischemic heart disease.

The study featured in the British Medical Journal looked specifically at plant based diets and their effect on the risk of ischemic heart disease and also stroke.

As part of the study, scientists took data from 48,188 people whom they followed for an average of 18.1 years.

The participants who had an average age of 45 years at the start of the study had no history of ischemic heart disease or stroke.

They were then assigned to one of three groups:

Using food questionnaires, the researchers assessed their overall food intake and nutrient levels.

They also collected information about factors such as body mass index (BMI), height and blood pressure.

During the 18.1 years of follow-up there were 2,820 cases of ischemic heart disease and 1,072 cases of stroke.

After adjusting for sociodemographic and lifestyle factors, the analysis revealed both positive and negative relationships between cardiovascular health and reduced meat intake.

The rate of ischemic heart disease among pescatarians was 13 per cent lower than that of meat eaters, while vegetarians had a rate that was 22 per cent lower.

Putting this into perspective, the authors of the study explained: This difference was equivalent to 10 fewer cases of ischemic heart diseasein vegetarians than in meat eaters per 1,000 population over 10 years.

Read the original:
How to live longer: The best diet to increase life expectancy according to new study - Express

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