StemCell Therapy

From zeroing in on different cancer cures to restoring vision and hearing to the blind and deaf2019 was a year filled with medical breakthroughs.

While some of these accomplishments may be varied in their stages of research, each notable study is just one more milestone towards treating some of humanitys most debilitating conditions.

So without any further ado, lets give it up for the top ten health and medical breakthroughs of 2019.

An exciting study that was published back in January found that exposure to blue light is an effective, non-pharmaceutical treatment for high blood pressure, which simultaneously reduces the risk of developing cardiovascular disease.

The researchers who conducted the study from the University of Surrey and Heinrich Heine University Duesseldorf discovered that exposure to whole-body blue light significantly reduced the systolic blood pressure of participants by almost 8 mmHg, compared to the control light which had no impact.

Whats even more remarkable is that the reduction of blood pressure from blue light is similar to what is seen in clinical trials with blood pressure lowering drugs.

Rather than targeting the typical rogue proteins associated with dementia, scientists found earlier this month thatfor the very first timethey have reversed dementia in mice with a drug that reduces inflammation.

Up until now, most dementia treatments have targeted the amyloid plaques that are found in people with Alzheimers disease. However, experiments conducted at the University of California, Berkeley suggest targeting inflammation in the brain might stop it in its tracks.

If you didnt already have enough reason to eat your vegetables, this study published back in May says that broccoli contains an amazing ingredient which could be the Achilles heel of cancer.

Broccoli is part of the cruciferous vegetable family, which includes cauliflower, cabbage, kale and Brussels sproutsand though many people dont like their taste, these vegetables contain a tiny, but powerful molecule that deactivates the gene responsible for cancerous tumor growth, known as WWP1.

Millions of blind people could have their vision restored using stem cells taken from the eyes of non-living donors, according to Scottish research publish back in March.

Thanks to the pioneering tissue transplant, eight patients with a common condition that destroys vision had the affected area repairedand two patients were even able to read again after having severe macular degeneration.

Back in April, Canadian researchers developed a new treatment for mobility-impaired Parkinsons disease patientsand the results were beyond their wildest dreams.

Scientists from Western University in Ontario published the results of a pilot study in which they used spinal implants to improve motor function in several patients with advanced Parkinsons.

Prior to the study, the patients were barely able to stand on their own without falling over or they were forced to depend entirely on wheelchairs for mobility. After getting the spinal implant, however, the patients are now capable of walking unassisted for the first time in years.

According to a report from May, people who experience anxiety symptoms might be helped by taking steps to regulate the microorganisms in their gut using probiotic and non-probiotic food and supplements.

Anxiety symptoms are common in people with mental diseases and a variety of physical disorders, especially in disorders that are related to stress. Previous studies have shown that as many as a third of people will be affected by anxiety symptoms during their lifetime.

Increasingly, research has indicated that gut microbiotathe trillions of microorganisms in the gut which perform important functions in the immune system and metabolism by providing essential inflammatory mediators, nutrients and vitaminscan help regulate brain function through something called the gut-brain axis.

In August, researchers at Johns Hopkins Medicine may have found the key to restoring hearing in people with irreversible deafness.

Using genetic tools in mice, researchers at Johns Hopkins Medicine say they identified a pair of proteins that precisely control when sound-detecting cells, known as hair cells, are born in the mammalian inner ear.

Scientists in our field have long been looking for the molecular signals that trigger the formation of the hair cells that sense and transmit sound, says Dr. Angelika Doetzlhofer, associate professor of neuroscience at the Johns Hopkins University School of Medicine. These hair cells are a major player in hearing loss, and knowing more about how they develop will help us figure out ways to replace hair cells that are damaged.

As MDMA is now being recognized as a groundbreaking cure for emotional trauma, a new clinic in Pennsylvania could become one of the first legally-sanctioned facilities for using the psychoactive drug on treatment-resistant PTSD in the United States.

Now that it has reportedly opened its doors in Wyndmoore, The Landing medical facility will specialize in using several psychoactive drugs to treat a variety of mental health disorders.

Particularly, it has been pushing to receive FDA approval on using MDMA-assisted psychotherapy for patients whose Post-Traumatic Stress Disorder has been untreatable.

Dental fillings may soon be a thing of the past, thanks to this breakthrough from Chinese scientists.

Enamel is the mineralized substance that protects the surface of teeth. Though it is one of the toughest tissues in our bodies, it is prone to degradation over time particularly as a result of consistent exposure to certain acids that are found in food and drinks.

We currently use resins and ceramics to fill in deteriorated enamel, but these fillings can often become loose within just a few years of their placementand with tooth decay being one of the most prevalent chronic diseases amongst humans, scientists have puzzled over how they can recreate enamel.

Until now, we have not been able to reproduce the toughened tissue because of its complex cellular structurebut back in September, a team of researchers from Zhejiang University School of Medicine developed a gel that makes enamel repair itself.

With pancreatic cancer ranking as one of the most deadly forms of cancer, researchers were excited to report on a promising new breakthrough for a treatment.

Pancreatic cancer, which maintains a 95% mortality rate, is resistant to all current treatments. Patients have extremely poor chances of surviving for five years after being diagnosedand since the disease does not show symptoms until the advanced stages, it is notoriously hard to diagnose.

However, this Tel Aviv University study published earlier this month finds that a small molecule has the ability to induce the self-destruction of pancreatic cancer cells. The research was conducted with xenograftstransplantations of human pancreatic cancer into immunocompromised mice. The treatment reduced the number of cancer cells by 90% in the developed tumors a month after being administered.

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After 35 years in Logansport, Dr. James Shell is passing the Shell Animal Clinic on to a new veterinarian, Dr. Andrew Bickett.

They closed the sale of the clinic the second week of December, and this past week has been one of transition. The change of hands comes after a long search by both men for the right fit.

My standards were high as I had to find someone who shared my deep love and appreciation for animals, as well as someone who has the medical skills to keep the clinic moving forward in the ever-evolving field of veterinary medicine and surgery, Shell stated in a letter he sent out to his clients.

I just felt fortunate to find someone like him to come in and take over, he said.

Bickett said he was searching for a place with the right veterinarian philosophy, standard of care and team, as well as the right community and Logansport proved right for him.

I like the kind of small town atmosphere, Bickett said.

Bickett is originally from Plano, Illinois, and hed been looking to buy a clinic that would put him closer to home than he was in central Kansas, where he worked in a small clinic after graduating from University of Illinois with his Doctorate in veterinarian medicine.

Hed looked at some in bigger cities, but they didnt seem right, he said. He wanted a place where he could get to know the community and his clients.

Bickett doesnt plan any major changes to the clinic, just an expansion of some services.

I do see exotic animals, which is something Dr. Shell didnt do a lot of, he said. That means hell take care of rabbits, snakes and hedgehogs, as well as other animals. Exotic is basically anything that isnt a cat, dog or farm animal, he said.

The clinics name will remain the same, at least for a while, and the staff will stay on. Bickett plans to update some of the equipment, but it wont be noticeable to most people, he said.

The familiar face of Archie lounging about the office will also remain the same. I inherited the cat, he said.

When Bickett first developed an interest in veterinarian medicine, it was my first dog, as it was for a lot of kids, he said. The dog had medical problems that required a lot of attention, and he regularly saw how vets did things and worked, he said.

For Shell, the call to this vocation came from growing up on a small farm and having small animals, and being in FFA and 4-H. His sister also worked for the local veterinarians office in high school and stayed to retirement, so that influenced him as well, he said.

He came to Logansport from his native Michigan in a similar situation as Bickett. He took over the clinic because it seemed like the proper fit.

During his 35 years here, hes seen clients for years and sometimes through multiple pets, and hell miss them and those working at the clinic.

Itll be a change for me, thats for sure, he said.

Shell plans to stay in Logansport, although he and his wife, Carolyn, will go to Arizona for winters and stay in their cottage at Winona Lake often. Hell be around to help at the clinic or consult with Bickett if necessary, but Shell believes that, at 70 years old, his days as a vet are over and Bickett is good for the clinic.

I dont think hes going to need my help much, Shell said.

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After 35 years, Shell Animal Clinic changes hands | Business - pharostribune.com

Washington State Universitys College of Veterinary Medicine gets calls frequently asking for free or reduced cost services.

Dont misread this and assume these calls are exclusively for clinical services in the Veterinary Teaching Hospital. While the majority are for such, still a few are from people or companies wanting free research services.

There are people around who believe that since the VTH is owned by the state, services must be free or deeply discounted. Nope. We are a fee-for-service facility like many state owned resources. And when it comes to undercutting private practices, we just dont have the ability to give away state resources like that.

We do have a program in our teaching hospital that is in perpetual need; the Good Samaritan Fund. It was started in the mid-1990s by WSU veterinary students to help animals in need of special care but whose owners could not afford treatment.

Today that mission has broadened slightly, and includes funding that may benefit accepting a very unique case that provides a unique teaching opportunity for veterinary students. Unknown ownership, or ownerless animals in need can also have an application made on their behalf.

An unknown ownership, patient might be say, a dog with no identification hit by a car. But perhaps the dog is well groomed, well fed and shows it is likely to be an owned animal. Good Sam funds, (as we refer to them) could be applied until ownership is established. An ownerless animal is one that has obviously been living at large for some time with no identification.

Good Sam funds are only awarded to treat common companion animals only at the Veterinary Teaching Hospital at WSU. Because the fund is always in need, there are significant limits on eligibility and the amount of funding awarded.

Eligible patients must have a need for life saving procedures and a reasonable prognosis for good long-term recovery. Patients will be either ownerless or owned by clients that cannot pay for care because of circumstances beyond the clients control. Unowned patients must have a temperament that does not prohibit transfer to a new owner.

Animals from animal control agencies, humane societies and business entities are not eligible for funds. The reason is, they are in fact owners of the animals they hold for placement. The college does many other things to benefit local and regional shelters. It is uncommon that are we able to provide the entire $1,000 upper limit toward a case. Owners are always responsible for some portion of the final billing not covered by Good Sam.

The team that reviews each application does so quickly. They have my total respect for their difficult task where needs far outstrip the funds ability to help. You can make application beginning here: vth.vetmed.wsu.edu/good-samaritan.

On that same page, you can donate funds, too. The end of the year is near and donations are tax deductible. You might want to consider making a donation to the WSU Foundation and directing it to the Good Samaritan Fund.The Good Samaritan originated as a biblical parable in the book of Luke. A traveler was beaten, stripped, robbed and left for dead. A priest came along and avoided the man. So did a Levite. It was the third person who earned the title Good Samaritan for stopping and rendering aid in the form of bandaging and applying oil and wine to the wounds.The Good Samaritan then loaded the man on his animal and took him to an inn for care. Thank goodness for both Good Samaritans and healthy animals.

Charlie Powell is the public information officer for the Washington State University College of Veterinary Medicine, which provides this column as a community service. For questions or concerns about animals youd like to read about, email cpowell@vetmed.wsu.edu.

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Year's end and the Good Samaritan | Life - Moscow-Pullman Daily News

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TOPEKA Twenty-one scholarship winners for the 2019-20 school year were recognized during the annual Kansas Livestock Association (KLA) Convention on December 4 in Wichita. A total of $23,000 was presented by the Kansas Livestock Foundation (KLF) and its partners.

Three students attending the Kansas State University College of Veterinary Medicine have been awarded $1,500 Cartridges for Cash (CFC) scholarships from Merck Animal Health and KLF.Joel Nelsonof Soldier is the son of Jerry and Jo Ann Nelson. He is a first-year veterinary student in the Kansas State University College of Veterinary Medicine.Alexis Pedrow, a second-year veterinary student, is the daughter Jeff and Teresa Pedrow of Richmond.Boyd Roenneis the son of Jason and Heather Roenne of Meriden. He is a first-year veterinary student. This award recognizes K-State veterinary school students with a career goal of being a large animal veterinarian.

Ryann Allisonof Fort Scott andKyndall Norrisof Riley each received a $1,000 CFC scholarship through KLF. Allison is the daughter of Tim and Carol Allison. She is a junior at K-State majoring in animal science with a pre-veterinary option. Norrisis the daughter of Kirk and Janice Norris. She is a senior at K-State majoring in animal science with a pre-veterinary option. This scholarship is presented to students entering or returning to a Kansas community or senior college and pursuing degrees in agriculture or a related field. CFC scholarships were funded by Mercks donation of 25 for each used Ralgro wheel or Revalor cartridge turned in to KLA.

Two K-State students each received a $1,500 Douglas A. Laue Memorial Scholarship.Shanie Adamsis the daughter of Brian and Stacie Adams from Meriden. She is a senior majoring in agricultural business.Grady Schuster, son of David and Kathy Schuster of Richmond, is a junior, also majoring in agricultural business. This scholarship is awarded to students entering their junior or senior year at K-State or Fort Hays State University and pursuing degrees in agriculture.

Gatlin Clawsonof Meade has been awarded the $1,000 Cattlemens Scholarship from GoBob Pipe & Steel and KLF. Clawson is the son of Dan and Tamra Clawson. He is a freshman at K-State dual majoring in agricultural economics and marketing. This scholarship is awarded to a student entering or returning to a Kansas community or senior college and pursuing a degree in agriculture or a related field.

Two $1,000 Hampel Oil/Mobil Delvac Scholarships have been presented to K-State students.Kinsey Griffith, daughter of John and Terry Griffith from WaKeeney, is a junior dual majoring in agricultural economics and animal science.Thomas Smithis the son of Jeff and Holly Smith from Windom. He is a junior majoring in agricultural economics with a specialty in global food systems leadership. This scholarship is awarded to students entering their junior or senior year at K-State or Fort Hays State University and pursuing degrees in agronomy, agribusiness or ag economics. Preference is given to applicants with a career goal of being actively engaged in a farming or feedyard enterprise.

Five K-State students from across the state have received $1,000 Youth in Agriculture scholarships from KLF.William A. Holemanis the son of William B. and Lora Holeman from Bronson. He is a sophomore majoring in feed science and management.Jamie Rockof Hope is the daughter of Brian and Candace Rock. She is a sophomore majoring in biological systems engineering.Courtney Sherbert, Morganville, is the daughter of Mike and Robin Sherbert. She is a sophomore majoring in agribusiness.Jordan Vandervortis the daughter of Jerry and Ingrid Vandervort of Wakarusa. She is a sophomore majoring in agricultural milling science and management.Kristopher Wagner, Satanta, is the son of Kevin and Maureen Wagner. He is a freshman majoring in agricultural economics. Funded by the KLF Club Calf Sale held during the Kansas Junior Livestock Show, these scholarships recognize students entering or returning to a Kansas junior or senior college and pursuing degrees in agriculture or a related field.

The Kansas CattleWomen (KCW) awarded $1,000 scholarships to five Kansas students.Grace Aust, daughter of Brad and Janell Aust from LaCygne, is a freshman dual majoring in animal science and agricultural communications and journalism at K-State.Taylor Dieball, the daughter of Cory and Sally Dieball from Little River, is a freshman majoring in animal science at Butler Community College.Samantha Fischeris the daughter of Dan and Connie Fischer from Silver Lake. She is a junior dual majoring in food science and industry and global food systems leadership at K-State.Katelyn Pinkstonis the daughter of Jay and Brenda Bohnenblust from Clay Center. She is a senior at K-State majoring in agricultural education.Marie Reveles, daughter of LaVerna Reveles from Hays, is a junior at K-State majoring in agricultural education. These scholarships, funded by the KCW silent auction held in the KLA Convention Tradeshow, are awarded to students entering or returning to a Kansas community or senior college and pursuing degrees in dietetics, food safety, agriculture or a related field.

Kristina Zergerwas awarded the $500 Fred H. Woodbury Memorial Scholarship through KLF. Zerger is the daughter of Tarry and Nancy Zerger of Cheney. She is a senior majoring in animal science at K-State. This scholarship is presented to a student attending a Kansas junior or senior college and pursuing a degree in agriculture. Preference is given to students residing within Chase, Franklin, Lyon, Osage or Wabaunsee county.

KLF was established in 1983 to operate solely and exclusively for charitable, scientific and educational purposes. For information about KLF scholarship opportunities or to receive an application, contact the foundation at 6031 S.W. 37th St., Topeka, KS 66614 or email[emailprotected].

KLA is a trade organization protecting the business interests of independent ranchers, feeders and dairy farmers. Members of the association are involved in all segments of the livestock industry, including cow-calf production, backgrounding, cattle feeding, swine, dairy and sheep. The associations work is funded by voluntary dues dollars paid by its 5,600 members.

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Hays & WaKeeney natives, other KS youth receive $23000 in scholarships - hays Post

From left, Drs. Jerome Masty, Sandra San Miguel and Glen Hoffsis.

An Ohio State University associate professor has been named the recipient of the 2019 AAVMC Distinguished Veterinary Teacher Award.

Jerome Masty, DVM, MS, Ph.D., will be recognized in early March at the Association of American Veterinary Medical Colleges annual conference and Iverson Bell Symposium in Washington, D.C.

The Distinguished Veterinary Teacher Award, presented by Zoetis, is a prestigious honor in the world of international academic veterinary medicine, according to AAVMC.

Dr. Masty, assigned to the department of veterinary biosciences, teaches first-year gross anatomy, second-year neuroanatomy of the nervous system and three second-year elective classes in surgical anatomy, feline anatomy and neuroanatomy.

Dr. Masty describes his teaching approach as one that goes beyond passive listening by engaging students through interactive notes and illustrative diagrams that help students to visualize and remember how different parts of the body work together, AAVMC stated. He continuously solicits and responds to student feedback and has demonstrated a commitment to teaching excellence as a mentor to numerous instructors and graduate teaching associates across various disciplines.

Five other veterinary educators will be honored alongside Dr. Masty. They are:

Did you know a subscription to Todays Veterinary Business is free to qualified veterinary professionals? All you have to do is sign up here (and renew each year). You also can sign up to receive the Todays Veterinary Business weekly e-newsletter.

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AAVMC chooses top educators of the year - Today's Veterinary Business Magazine

Students may receive two bachelors degrees from two Nebraska schools all in the span of four years in a new biology and agriculture program.

Wayne State College and the University of Nebraska-Lincoln announced a new dual-degree initiative, the applied science degree program, earlier this month. Students may earn a life sciences degree with a concentration in biology from Wayne and an applied science degree with concentrations in agriculture and natural resources from UNL.

The degree is one of its kind between the two schools and faculty have been working on it since September 2018, said Tammy Evetovich, dean of the Wayne State School of Natural and Social Sciences.

What I love about this program is that its so flexible and innovative, Evetovich said. People can take it and do what they want with it.

Students in the program will spend three years at Wayne States School of Natural and Social Sciences and finish their last year at UNLs College of Agricultural Sciences and Natural Resources (CASNR) to receive both degrees. Graduates will be prepared for jobs related to farming, ranching, parks and recreation and land management.

Participants may choose to either relocate to the UNL campus in Lincoln for the last year or finish their education online with UNL and in local lab settings at the nearby Haskell Ag Lab in Concord.

The program is part of the Northeast Nebraska Agriculture and Natural Resources Education Compact, an agreement signed in October between seven institutions, according to a previous Daily News article.

The goals of the partnership are to provide education platforms in resilient food, energy, water and societal systems in alignment with career opportunities, as well as prepare teachers and curriculum to respond to the increased need for agricultural science and STEM (Science, Technology, Engineering and Math) educators.

Additional partnership goals are intended to encourage workforce development solutions for the agriculture and natural resources industries in Northeast Nebraska.

We really needed to think about opportunities for learners in the northeast part of the state, said Tiffany Heng-Moss, dean of the UNL College of Agricultural Sciences and Natural Resources (CASNR). One of the things we were focusing on is how we can leverage the strength of each of our institutions to best suit the needs of our learners. Wayne State is an excellent institution and CASNR and Wayne State share a lot of the same goals. It seemed like a natural partnership.

Evetovich said one of the main goals of the dual-degree program is to retain young people in Nebraska, especially in agriculture and natural resources.

Agriculture is very important in Nebraska, Evetovich said. We want to keep young, talented people in our community. The last thing I want is people in this region to think they have to leave to get an agriculture degree.

Freshman Evelina Krie was a major in pre-veterinary medicine at Wayne State College until she learned about the dual-degree program, she said. She will be one of the few students starting the program in January.

Im more interested in the biology part, but I also come from an agricultural background, so I like that it suits me better, Krie said. Im still planning on going into vet school, but I wanted to back myself up with more options. I thought it was neat how it gave you two degrees in four years.

While the program wont officially be offered until the 2020 fall semester, students are working with professors to begin the program in the 2020 spring semester, Evetovich said. Interested students may visit http://www.wsc.edu/info/20446/applied_science for more information.

People are getting really excited about this, Evetovich said. (UNL) has been great to work with, and it was truly a collaboration. We are happy to place young professionals in agriculture in Nebraska. Its something I think is very special.

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Wayne State partners with UNL to offer dual-degree program - Kearney Hub

From a horned ram wandering a neighborhood to lizards abandoned by their owners, animals in need of a home are welcome at this Baton Rouge shelter.

Though dogs and cats make up the majority of the animals that find their way to the Companion Animal Allianceshelter in Baton Rouge, the organization takes in a Noahs Ark of potential companions.

We get it all, said CAA Executive Director Jillian Sergio. As long as it isnt (native) wildlife, it comes to us.

The shelter near the Mississippi River on the outskirts of LSU's campus is a safe haven for pets that people have kept and, for whatever reason, can no longer care for.

Earlier this month, a cow came in after being hit by a car, requiring it to undergo treatment at the nearby LSU School of Veterinary Medicine. And many of 25 horses that lived in the shelters outdoor pasture this year came through neglect cases across East Baton Rouge Parish, Sergio said.

A few years ago, animal control officers picked up a lemur that someone had been keeping.

The lemur was the weirdest thing, Sergio said. We dont know the whole story because it was a stray.

They transferred the animal to a zoo.

She's kept a running total of this year's odd animals being fostered at the shelter. They include: 18 pigs, 14 chickens, 12 birds, eight goats and two donkeys.

Among the strangest this year, Sergio said, was a ram that been meandering through a Baton Rouge subdivision. The shelter is still unsure where the 5-foot-tall horned animal came from.

CAA partners with Rescue Me Animal Welfare, a Walker-based organizationthat has a broader reach and can find livestock and other exotic animals a home in a different parish or another state.

There are many reasons these animals have been forsaken by their owners, but the most common one is that the owners can no longer care for the animal and take them to the shelter in hopes of finding them a better home.

Livestock sometimes get picked up by animal control agents before the owners realize they're missing.

Sadly, sometimes the animals are set loose in the wild.

Laurie Font, a science teacher at Baton Rouge Magnet High School, has fostered dozens of reptiles in the past decade and is currently caring for a 5-foot-long red tail boa constrictor that a police officer found at the side of a road.

People get overwhelmed, so they release them, Font said. A lot of the ones we get in are not in the best of shape."

Some of the cold-blooded critters she's taken in over the last decade need serious veterinary care for infections or bone problems from being malnourished.

Font uses these animals in some of her environmental classes to expose city kids to critters they may never have encountered, as well as a chance to highlight cautionary tales of irresponsible pet ownership.

Iguanas and other reptiles are cheap to buy when theyre young but tend to be a lengthy commitment and have specialized needs and diets.

Finding homes for reptiles typically isnt difficult, but requires serious owners who can take care of them for several years. A red-tail boa, for example, can live 30 years.

Stray reptiles present a greater challenge, especially for those abandoned in the wild. Because they can survive in Louisianas mild climate, Font said, they can pose a threat to the ecosystem.

Florida in recent years has seen a boom in iguanas that have wreaked havoc on the environment, gobbling up the abundant plant life there with no natural predators to keep them in check.

Concerned about a similar possibility in Louisiana, Font said, CAA been encouraging people to take their pets to a shelter if they can no longer care for them.

"There are places you can turn to help versus just letting them go," Font said. "That's just not a viable option."

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From bearded dragons to a ram wandering a Baton Rouge neighborhood, animal shelter takes in all - The Advocate

This years campaign began on World Rabies Day on Sept. 28. The program is staffed entirely by volunteers and a team of veterinarians who have already vaccinated 7,000 dogs and 1,200 cats.

Vaccines work by stimulating the immune system (the bodys defense system against pathogens) to recognize and mount a response against viruses. So the next time a vaccinated dog encounters rabies, it will not develop the disease or become infectious to other animals. This is called immunity, and it stops a potential outbreak in its tracks.

Its impossible to vaccinate every single dog in the area, but once enough animals are vaccinated, the disease becomes so rare that it cannot be maintained in a population, no longer poses a threat and can hopefully be eliminated. This is how human vaccines work, too!

In addition to these critical free vaccination services, it is equally important to inform dog owners of the risk that unvaccinated dogs might pose to human health. To accomplish this, Dr. Kamau and Dr. Milnes are also conducting research to find out what people know (and dont know) about rabies.

This kind of research is called a knowledge, attitudes and practices study (or KAP study). It can help identify gaps in community knowledge and behaviors that might leave people vulnerable to disease exposure. For example, many languages refer to rabies as mad dog disease, leading to a common misunderstanding that the disease only affects dogs and people are not at risk.

The principle of One Health means that the health of domestic animals, people, wildlife and the environment are all intertwined. The global burden of rabies demonstrates just how closely our health is interrelated, and illustrates the value of veterinary medicine to human health and wildlife conservation. In short, vaccinating dogs also protects wildlife and saves human lives.

Veterinary fellows Dr. Maureen Kamau and Dr. Ellie Milnes are supported through a partnership between the Smithsonian Conservation Biology Institute, Mpala Research Centre, Kenya Wildlife Service and Ol Jogi Wildlife Conservancy, demonstrating the importance of this work to many stakeholders in the region.

Generous core support for the Global Health Programs training program is provided by Morris Animal Foundation and Dennis and Connie Keller.

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Stopping Rabies in its Tracks: How Canine Vaccines are Saving Lives in Kenya - Smithsonian's National Zoo and Conservation Biology Institute

Helen Aristar-Dry likes to garden, but she doesnt want the aches and pains that could follow an enjoyable time spent out at her 1-acre property in Dripping Springs.

Ive always been interested in easier ways to garden, said Aristar-Dry, 73, who has had rheumatoid arthritis for about 50 years. For someone like herself, she said, Youre always looking for ways to lessen the strain on your joints.

Rheumatoid arthritis is an autoimmune and inflammatory disease that often affects hands, wrists, knees and ankles. Symptoms can include swelling, pain and stiffness in more than one joint, as well as fatigue and weakness.

Over the years having had several surgeries and used a wheelchair at times she has learned tactics to help her out. Sitting alongside her raised bed gardens used for growing Swiss chard and kale, along with other things she is glad she can still relish working with flowers, vegetables and dirt.

Its just really a good pastime, she said.

Aristar-Dry has a doctorate in linguistics, and after she retired in 2013, she had more time for a favorite hobby. She became a Hays County master gardener in 2015, and she has researched a variety of ways to make it easier for her in the garden.

Evaluating her resources and careful planning have helped, Aristar-Dry said. In addition to finding assistance for heavy jobs, she divides up large tasks into shorter chunks.

I rarely work more than 30 minutes at a time, she said. By then my hands will be hurting, so its time to quit.

If I overdo it, Im going to feel bad, she said. She also keeps a to-do list, so I can see whats a good job that fits the time I have. I dont do big projects.

In addition, she opts to use equipment that isnt weighty. I use a childrens rake with a long handle, because its much lighter, she said. Its less stress on the joints if you dont have to carry heavy stuff around. She uses a cart, rather than a wheelbarrow, to move large items such as bags of dirt.

She needs to be more vigilant about keeping her tools sharpened so they dont require as much strength to use, she said. Thats one I need to work on, but it makes a big difference.

Effective use of logistics has also aided her, and that can be as simple as storing her tools near the garden. Shes a big advocate of raised beds of all kinds where she can even sit down to work.

Theyre less demanding physically, she said. As well, she wishes she had more space between garden beds to allow more room for a bench or a cart to get through the path.

She carefully selects plants that are easier to care for, such as drought-tolerant natives, she said. As well, she likes to use plants that have been designated as Texas Superstars, which perform well under Texas tough growing conditions, according to texassuperstar.com.

Aristar-Dry prefers to use perennial plants rather than annuals, because with perennials, you put them in once and they come back, she said. Perennials are just much easier.

She keeps in mind some ergonomic principles, such as using her joints in a neutral position, which she described as about midpoint of their range, and other basics. In addition, she helps limit discomfort through the selection of ergonomically designed gardening tools. These tools help the user reduce stress and injuries from overuse of the body.

She has some long-handled tools that can help let her back remain straight. Some tools such as a waist-high weeder have an O-shaped handle that offers more grip surface, and its easy to use two hands with, she said.

Along with other selection criteria, she picks various tools that can let her keep her wrist straight, she said. (Often, she said, many tools require users to bend their wrists.)

Other implements can also help; she uses a special faucet turner to make it easier to turn on and off the water outside so she doesnt have to use as much strength. She uses a garden kneeler that can serve as a seat, she said. When I sit down and keep my back straight, I can work a whole lot longer.

Putting together information on the tactics she uses, as well as including more details about ergonomics and such, she has given a presentation on called Ergonomic Gardening: Gardening to Avoid Aches and Pains about a half-dozen times at the Hays County Master Gardeners Associations In the Garden series. Emphasizing that she doesnt have any medical training but that she has found these methods useful to her.

The talk is popular, said Phyllis Janowski, past president of the Hays County Master Gardeners Association.

People found it helpful to learn about some measures they could take, even for those who dont usually get aches and pains from gardening, she said.

Now that Aristar-Dry has found workarounds to help her, she still gets to take joy in the garden, she said. I think its really just rewarding to be out there with growing things.

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Find the right tools to garden with arthritis - austin360

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Arthritis is caused by inflammation of the joints. There are many foods and ingredients that can ease inflammation and may help relieve some of the joint pain associated with arthritis. Adding these foods to a healthy diet can help alleviate our arthritis symptoms. Lets have a look on list of food and ingredients that we can try using at our homes in order to get some relief from the arthritis-related pain.

Grains

While considering our options in the bread, cereal, and pasta, we should avoid refined grains. Not only are they highly processed grains but limited in nutrition, can lead to inflammation throughout the body. For Example, switching from refined flour to whole-wheat flour in our recipes can increase the intake of nutrients and potentially lower inflammation. Likewise, barley is filled with 6 grams of fiber per cup, a perfect addition to soups, stews and risotto dishes.

Nut and seeds

Nuts and seeds are a useful component in our diet. Most importantly it offers a variety of health benefits to people with arthritis. With their high ALA content, nuts like walnuts are omega-3-containing and researchers studying their effects have found that they lower C-reactive protein (CRP), an inflammation marker linked to an increased risk of cardiovascular disease and arthritis. Likewise, chia seeds are also an excellent source of anti-inflammatory ALA, but their greatest benefit is likely their high fiber content.

Fruit and vegetables

Fruits are naturally sweet and have a substantial amount of antioxidants, protein, vitamins, minerals, and other nutrients, just like red raspberries, tart cherries and strawberries are filled with antioxidants that help to get rid of radicals that encourage inflammation whereas Vegetables are rich in antioxidants and other nutrients that protect against cell damage and lower inflammation throughout the body, including in the joints. For example, fresh, leafy vegetables such as broccoli, spinach, brussels sprouts, kale, swiss chard, and bok choy are loaded with antioxidants such as vitamins A, C, and K which protect cells from free radical harm.

Spices

According to traditional Eastern medicine, ginger and turmeric are two spices that have anti-inflammatory properties. Along with its anti-inflammatory properties, some studies have shown ginger can also reduce osteoarthritis symptoms, if not in food one can also opt-in the form of a herbal supplement -like IMOVE containing popular, active and trusted pain management ingredients such as ginger and turmeric. It also includes Glucosamine & Chondroitin for joint repair and lubrication, thereby offering full joint treatment.

Fish

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are called marine fatty acids as they are derived from fish, adding omega-3 sources to our diets inflammation could be reduced. Fatty fish such as salmon, tuna, sardines, and mackerel are the best sources of marine omega-3s. Anti-inflammatory effects of omega-3s are helpful not only for the relief of arthritis but also for the prevention of other inflammatory diseases, such as heart disease. It is usually suggested to eat 3 to 6ounce serving of these fish two to four times a week to reduce inflammation and protect the heart Omega-3-rich fishes are also high in mercury, which causes brain and nervous system can harm if consumed in large quantities. Its important to choose smaller fish that have less mercury.

(Disclaimer: Writer is Sargam Dhawan, Director, Planet Herbs Lifesciences Pvt Ltd. Views expressed are a personal opinion.)

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Food and ingredients to cure arthritis! - Elets

Study on the Rheumatoid Arthritis Treatment Market

The comprehensive report published by Future Market Insights (FMI) offers an in-depth intelligence related to the various factors that are likely to impact the demand, revenue generation, and sales of the Rheumatoid Arthritis Treatment Market. In addition, the report singles out the different parameters that are expected to influence the overall dynamics of the Rheumatoid Arthritis Treatment Market during the forecast period 2017-2027.

As per the findings of the presented study, the Rheumatoid Arthritis Treatment Market is poised to surpass the value of ~US$ XX by the end of 2029 growing at a CAGR of ~XX% over the assessment period 2017-2027. The report includes a thorough analysis of the upstream raw materials, supply-demand ratio of the Rheumatoid Arthritis Treatment in different regions, import-export trends and more to provide readers a fair understanding of the global market scenario.

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The presented study addresses the following queries related to the Rheumatoid Arthritis Treatment Market:

The presented market report dives deep into understanding the business strategies adopted by leading market players in the global Rheumatoid Arthritis Treatment Market. Further, the SWOT analysis for leading market players is enclosed in the report along with the revenue share, pricing analysis, and product overview of each company.

The extensive study on the Rheumatoid Arthritis Treatment Market pinpoints the different factors that are likely to influence the prospects of the Rheumatoid Arthritis Treatment Market in each region.

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Rheumatoid Arthritis Treatment Market Industry Analysis, Trend and Growth, 2017-2027 - Info Street Wire

Goldman Sachs is bullish on these health care stocks.

Last U.S. presidential election season, health care stocks didn't perform very well. Political headline risk related to drug pricing and "Medicare for All" could weigh on health care valuations again in 2020. Fortunately for investors, the Goldman Sachs analyst team says there are still plenty of opportunities for long-term investors to buy health care stocks heading into an election year. Goldman says valuations are reasonable, aggressive policy changes are unlikely, innovation and product development are booming and there is consolidation potential in the sector as well. Here are Goldman's eight high-conviction health care stock ideas for 2020.

Amgen (ticker: AMGN)

Amgen is a global biopharmaceutical company that markets drugs for oncology and inflammation. Analyst Terence Flynn says Amgen will likely outperform consensus revenue and earnings per share estimates in 2020 and 2021. After winning a patent battle against arthritis drug Enbrel in August and acquiring plaque psoriasis and psoriatic arthritis drug Otezla shortly thereafter, Flynn says Amgen is on track to grow revenue by between 4% and 8% annually over the next four years. Data on Tezepelumab and AMG 510 may also be near-term catalysts. Goldman has a "buy" rating and $279 price target for AMGN stock.

BioMarin Pharmaceutical (BMRN)

BioMarin is a biopharma company focused on the treatment of serious rare and ultra-rare diseases. Analyst Salveen Richter says BioMarin has a diversified portfolio of treatments that is positioned to deliver more than 20% revenue growth in 2020. Richter estimates BioMarin's seven core commercial products will generate a combined $1.7 billion in fiscal 2019 revenue and peak at more than $6 billion in combined revenue in 2030. Richter estimates peak sales for BioMarin's gene therapy treatment for hemophilia A at $1.3 billion. Goldman has a "buy" rating and $157 price target for BMRN stock.

Incyte Corp. (INCY)

Incyte is a biotech company focused on hematology, oncology and inflammation. Richter says Incyte's lead drug Jakafi is on track for $2.9 billion in peak 2028 sales. In addition, he says Incyte has a strong development pipeline of 21 drugs, with eight already in pivotal-stage clinical trials. Phase III Gravitas-301 data for itacitinib in steroid nave acute graft-versus-host disease should be a near-term catalyst. Richter is anticipating updates from the company's dermatology franchise in the first half of 2020. Goldman has a "buy" rating and $122 price target for INCY stock.

Iqvia Holdings (IQV)

Iqvia is a global advanced analytics, technology and life sciences research company. Analyst Robert Jones says Iqvia is a large-cap growth stock, and its research segment should be particularly strong in 2020. Jones says the market isn't fully appreciating Iqvia's technology segment, which is producing healthy organic revenue growth due to solid demand for real-world evidence. Jones says the election cycle could drive RWE demand in 2020, differentiating Iqvia from other health care stocks that have negative headline risk. Goldman has a "buy" rating and $191 price target for IQV stock.

UnitedHealth Group (UNH)

UnitedHealth is one of the largest global managed care organizations. Analyst Stephen Tanal says United's commercial, Medicare Advantage and Medicaid businesses are all attractive, and its Optum acquisition gives the company access to a unique collection of data and services. Goldman is projecting more than $19 billion in operating cash flow in 2020, with only about $2.3 billion needed for capital expenditures and share buybacks. Tanal says 2020 guidance is conservative, and UnitedHealth is well-positioned for at least 13% annual EPS growth. Goldman has a "buy" rating and $330 price target for UNH stock.

Vertex Pharmaceuticals (VRTX)

Vertex is a biopharma company focused on developing treatments for cystic fibrosis. Vertex is also developing a pipeline of therapies for pain, sickle cell disease, kidney disease and other conditions. Vertex shares gained 25% in the past three months, and Richter says Vertex is on track for impressive EPS growth in the coming years due to its multiple pipeline drivers. Goldman has a "buy" rating and $285 price target for VRTX stock.

Story continues

Dentsply Sirona (XRAY)

Dentsply Sirona is one of the largest manufacturers of dental office solutions, including consumables and high-end equipment. Analyst Nathan Rich says Dentsply Sirona's new Primescan intraoral scanner should benefit from long-term demand and be a major contributor to 2020 revenue growth. In the longer-term Primescan upgrade programs could drive additional revenue upside. In addition, new product launches and the company's One DS loyalty program could be bullish catalysts. Rich says the company's restructuring efforts appear to be ahead of schedule, suggesting potential margin growth opportunities ahead. Goldman has a "buy" rating and $66 price target for XRAY stock.

Zoetis (ZTS)

Zoetis is the global leader in animal health medicines and vaccines. Rich says Simparica Trio could be the world's first $1 billion animal health drug and has the potential to add as much as 30 percent to Zoetis EPS. Favorable pricing and product mix should contribute to cash flow growth and boost margins as well. Finally, Rich says the company's expansion to diagnostics and new pain drugs may be long-term growth opportunities as well. Pet care has also historically been relatively recession-proof, potentially limiting downside risk. Goldman has a "buy" rating and $148 price target for ZTS stock.

Goldman Sachs' top health care stocks for 2020:

-- Amgen (AMGN)

-- BioMarin Pharmaceutical (BMRN)

-- Incyte Corp. (INCY)

-- Iqvia Holdings (IQV)

-- UnitedHealth Group (UNH)

-- Vertex Pharmaceuticals (VRTX)

-- Dentsply Sirona (XRAY)

-- Zoetis (ZTS)

More From US News & World Report

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Goldman's 8 Highest-Conviction Health Care Stocks to Buy - Yahoo Finance

Global Drugs for Rheumatoid Arthritis Market research report gives a comprehensive outlook of the markets 2019-2025 and offers an in-depth summary of the current market status, historic, and expected way forward for the Drugs for Rheumatoid Arthritis Market. Additionally, to this, the report provides data on the restraints negatively impacting the markets growth. The report includes valuable information to assist new entrants, as well as established players, to understand the prevailing trends in the Market.

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Key Objectives of Drugs for Rheumatoid Arthritis Market Report: Study of the annual revenues and market developments of the major players that supply Drugs for Rheumatoid Arthritis Analysis of the demand for Drugs for Rheumatoid Arthritis by component Assessment of future trends and growth of architecture in the Drugs for Rheumatoid Arthritis Market Assessment of the Drugs for Rheumatoid Arthritis Market with respect to the type of application Study of the market trends in various regions and countries, by component, of the Drugs for Rheumatoid Arthritis Market Study of contracts and developments related to the Drugs for Rheumatoid Arthritis Market by key players across different regions Finalization of overall market sizes by triangulating the supply-side data, which includes product developments, supply chain, and annual revenues of companies supplying Drugs for Rheumatoid Arthritis across the globe

Major Players included in this report are as follows AbbVie IncHoffman-La Roche AGAmgen IncPfizer IncBristol-Myers Squibb CoJohnson & JohnsonUCB Biosciences IncMitsubishi Tanabe Pharma CorpBiogen IncMerck & CoMarket Segment by Product TypePharmaceuticalsBiopharmaceuticals

Drugs for Rheumatoid Arthritis Market can be segmented into Product Types as PrescriptionOTC

Drugs for Rheumatoid Arthritis Market can be segmented into Applications as HospitalClinicsOther

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Drugs for Rheumatoid Arthritis Market: Regional analysis includes:Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)Europe (Turkey, Germany, Russia UK, Italy, France, etc.)North America (United States, Mexico, and Canada.)South America (Brazil etc.)The Middle East and Africa (GCC Countries and Egypt.)

Target Audience: Drugs for Rheumatoid Arthritis Equipment Manufacturers Traders, Importers, and Exporters Raw Material Suppliers and Distributors Research and Consulting Firms Government and Research Organizations Associations and Industry Bodies

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Report structure:In the recently published report, DataIntelo.com has provided a unique insight into the Drugs for Rheumatoid Arthritis Industry over the forecasted period. The report has covered the significant aspects which are contributing to the growth of the global Drugs for Rheumatoid Arthritis Market. The primary objective of this report is to highlight the various key market dynamics listed as drivers, trends, and restraints.

These market dynamics have the potential to impact the global Drugs for Rheumatoid Arthritis Market. This report has provided the detailed information to the audience about the way Drugs for Rheumatoid Arthritis industry has been heading since past few months and how it is going to take a shape in the years to come.

DataIntelo has offered a comprehensive analysis of the Drugs for Rheumatoid Arthritis industry. The report has provided crucial information about the elements that are impacting and driving the sales of the Drugs for Rheumatoid Arthritis Market. The section of competitive landscape keeps utmost importance in the reports published by DataIntelo. Competitive landscape section consists of key market players functioning in the worldwide industry of Drugs for Rheumatoid Arthritis.

The report has also analysed the changing trends in the industry. Several macroeconomic factors such as Gross domestic product (GDP) and the increasing inflation rate is expected to affect directly or indirectly in the development of the Drugs for Rheumatoid Arthritis Market.

Table of Contents1 Industry Overview of Drugs for Rheumatoid Arthritis2 Manufacturing Cost Structure Analysis3 Development and Manufacturing Plants Analysis of Drugs for Rheumatoid Arthritis4 Key Figures of Major Manufacturers5 Drugs for Rheumatoid Arthritis Regional Market Analysis6 Drugs for Rheumatoid Arthritis Segment Market Analysis (by Type)7 Drugs for Rheumatoid Arthritis Segment Market Analysis (by Application)8 Drugs for Rheumatoid Arthritis Major Manufacturers Analysis9 Development Trend of Analysis of Drugs for Rheumatoid Arthritis Market10 Marketing Channel11 Market Dynamics12 Conclusion13 Appendix

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Drugs for Rheumatoid Arthritis Market 2019 Global Share, Trend, Segmentation and Forecast to 2025 - Market Research Sheets

Global Septic Arthritis Treatment Market 2019 by Company, Regions, Type and Application, Forecast to 2024offers an orderly representation of the market that proposes a positive growth rate in the upcoming years. The report contains the combinations, methods, summarized study, and data gathered from various sources. The research experts have studied the historical data and provided an idea of the direction this market will take in the forthcoming years. The report involves key insights pertaining to industry deliverables, particularly market trends, market share, market competitors and recognized players, market size, current valuation, and revenue estimations for the forecast period from 2019 to 2024. The research study is reliable, wide-ranging, and the result of strong analytical research on theSeptic Arthritis Treatmentmarket.

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The report investigates evaluates theSeptic Arthritis Treatmentmarket on the basis of market segments and geographical areas and current market trends. Various factors such as development, rapidly increasing demand, economic stability are directly and indirectly fuelling growth in the market are also covered in the report. An assessment of the technical barriers, other issues, as well as market restraints is determined. Key market competitors who majorly hold the market shares in terms of demand, supply, and income through their products, services, and after deal processes are studied and their comprehensive abstract has been provided in the report.

The report encloses a precise evaluation of theSeptic Arthritis Treatmentmarket, including growth rate, current scenario, and volume inflation prospects, on the basis of Porters Five Forces analysis. It provides reliable and authentic projections regarding the market. The report has thoroughly studied the market report on the basis of R&D developments, distribution channels, industrial penetration, manufacturing processes, and revenue.

Lupin Pharmaceuticals (US), F. Hoffmann-La Roche Ltd (Swtizerland), AbbVie Inc (US), Amgen Inc (US), Bristol-Myers Squibb Company (US), Johnson & Johnson (US), Pfizer (US),

The global version of this report with a geographical classification such as:

North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, Colombia), Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

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Auranofin is a gold-containing salt with chemical formula and name C20H34AuO9PS and Gold, 2,3,4,6 tetraacetate respectively. It is used for treatingarthritis and is classified as an antirheumatic agent by World Health Organization and is also called disease-modifying antirheumatic drug (DMARD). Antirheumatic drugs are the ones that are used in the treatment of rheumatism. Auranofin is known by different names in different countries. Auranofin improves arthritis symptoms like painful, tender and swollen joints and morning stiffness. Also, it is said to decrease the pain by reducing inflammation and it slows down or stops the immune system from attacking the joints and Auranofin acts by inhibiting DNA synthesis. Auranofin should be considered only when other non-steroidal anti-inflammatory drugs and appropriate steroids are ineffective in controlling the symptoms of rheumatoid arthritis.

The use of Auranofin is increasing as the number of people having arthritis is increasing. This can driveauranofin marketas it is effective and is reported to exhibit less serious side effects as compared to other drugs that are used for treating arthritis.

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Increasing Demand for Auranofin Owing to Rising Arthritis Demographics

According to CDC reports, arthritis is still a serious health crisis in the U.S. and it is a global epidemic as well. Recent estimates showed that nearly 91 million Americans might have arthritis (37%), including one- third of those aged bwtween18 to 64 plus 300,000 children approximately. The underlying reasons for the increasing population with arthritis are obesity, lack of physical activity, Vitamin D deficiency and others. Also, Arthritis is rising in Europe, Latin America and in Middle East Africa and reasons being sedentary lifestyle and in some cases, heredity. The growing population with arthritis is anticipated to fuel the Auranofin market as it is less severe than the other drugs that serve the same purpose.

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The Auranofin market is rising because of the growing arthritis population and it is expected to grow in the coming years. The key players of Auranofin include Ferro Pfanstiehl Laboratories, Inc.,Prometheus laboratories inc, JOHNSON MATTHEY INC, Lek Pharmaceuticals d.d, Medichem SA and Company Overview ofLonza Group Ltd and others. Apart from them, more industrialists and manufacturers are showing a keen interest in the Auranofin as the demand for the auranofin, due to the rising population with arthritis is growing and is expected to escalate until and unless people dont practice healthy lifestyle and engage themselves in physical activities.

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Auranofin Market Status And Forecast 2027, By Players, Types And Applications - Market Research Sheets

Beloved Maine childrens singer Rick Charette and his Bubblegum Band played their 29th annual holiday concert at St. Josephs College earlier this month. It was a sold-out show, standing room only. As always, the price of admission was a new, unwrapped toy for a child in need.

Its likely to be Charettes final public performance ever.

Health challenges are forcing the 72-year-old author of Alligator in the Elevator and I Love Mud off the stage. But he doesnt want to make a big deal of it.

Id like to have people thinking of the music when they think of me, rather than my physical condition, Charette said. Thats why Im downplaying it.

He hinted at his retirement back in 2018, and while Charette is reluctant to talk about specifics, he said a combination of arthritis, a nagging shoulder injury and a touch of Parkinsons disease are making it difficult to perform his energetic shows. Charette would rather stop while hes still at the top of his game, rather than fizzle out and fade away.

I knew I should have said something about it being the last one, but I just couldnt bring myself to do it, Charette said. It would have been just too sad.

For now, hes telling people who want to book him to call back in the spring, when he might feel better. Charettte knows thats not likely, though.

Im ever hopeful but still accepting that, at some point, some things are the way they are, he said.

In the meantime, Charette can look back on an exceptional 35-year career of writing, singing and making children happy.

Charette grew up in Westbrook. When he graduated from Cheverus High School in 1965, music was already a big part of his life.

Pete Seeger was my hero in terms of what he could do to have the whole audience in the palm of his hand, singing along, Charette said over a cup of coffee at his kitchen table in Windham.

He also admired Bob Dylans songwriting.

While earning a degree in English at the University of Southern Maine, Charette found moderate local success as a folksinger, wielding an acoustic guitar, dulcimers and the occasional banjo. He played the bar and coffeehouse circuit and opened for better-known acts such as Tom Rush.

He wasnt always happy, though.

Playing for adults, I was a nervous wreck, Charette said. It was painful. Then, I played a little bit for kids, and it was a whole different vibe. I seemed to relax and be comfortable.

He knew hed found his niche.

Singing with kids meant he did not have to play in smoky bars anymore where the music was secondary to drinking and gabbing. Kids didnt yell requests for Neil Young all night, either.

I liked the hours a lot better, Charette said.

Bubble Gum was the first childrens song he wrote. Kids immediately latched on to its gentle, bouncing cadence and quirky lyrics: I dont like frog legs cause they smell like feet. You can take away the liver. Give me something sweet Bubble gum, bubble gum. Lots of fun with my bubble gum.

By 1983, Charette had recorded an albums worth of original material. He also scored a distribution deal with Activity Records.

When the record came out, it gave me credibility as a performer for kids, he said.

The company passed on his second batch of songs in 1985. They thought Charettes tunes werent educational enough. They wanted more colors and numbers.

At that juncture, Charette and Roy Clark, his piano player and arranger, hatched a plan. They both mortgaged their homes and started their own company, Pine Point Records. Their first release was the album Alligator in the Elevator.

That went on to sell several hundred thousand copies, Clark said.

Charettes best-known song, I Love Mud, appeared on that record.

All I have to do is sing, Mud, mud, I love mud, and everyone finishes the rest of the chorus, Charette said. And its usually the grown-ups singing loudest.

Clark said its Charettes ability to listen to kids, to take their interests seriously, that makes him a good songwriter. Instead of deciding what a child should be singing, he finds out what kids want to sing about.

Thats special. Thats unique, Clark said.

All told, Pine Point Records released 11 albums by Charette. The latest came in 2016.

With a hit childrens record, Charette was soon playing concerts and teaching school songwriting workshops across the country. Many of Charettes his best-loved songs include hand motions or sign language to help keep wee ones engaged. Skunk, bear and alligator puppets also played prominent roles in his performances.

Its beautiful pandemonium, said bassist Mike Burd of Industry. Burds played in the Bubblegum Band for about three years. Rick is a totally humble, gentle, self-effacing, completely transparent, honest guy. The kids fall all over him and follow him all around. The parents do the same thing and, in many cases, the parents parents did the same thing. He has this multigenerational audience. Everybody knows all the words to every song.

Charette has always shied away from politics or broad moralizing in his songs, focusing instead on warmth, fun and singability.

I just want it to be a happy time for them, he said. I think it makes a difference for kids, later in life just knowing someone cares for them giving them that time to play.

Its been a good life for Charette. Hes a happily married father of three and grandfather of two. Hes a longtime resident of Windham, living in an immaculate condo with access to Sebago Lake. Recently, however, hes started to feel his age.

My 60s were good, Charette said. But it seems like when I hit 70, I hit a wall.

Thats when he had a bicycle accident. Charette broke his collarbone and a few ribs, going down hard on a hidden curb.

The bones healed, but his shoulder has never been the same, making it hard to play the guitar. Charette also has arthritis and Parkinsons disease which hes opening up about for the first time.

Ive been reluctant to put that out there in public, he said. Its just the beginning stages and sometimes, when people know something like that about you, they start treating you differently.

He doesnt want that. Charettes early symptoms are manifesting mostly in tight muscles. They make it hard to move around. His feet often feel leaden, immobile.

I wouldnt want to present that onstage. You want kids dancing around, he said. In my mind, in my head, Im still right there. But physically, its just too difficult.

Looking ahead, Charette dreams of hiking when the weather gets nice again. He also imagines days when he might feel well enough to volunteer singing with children, stuck in the hospital. Hes still thinking up songs, too. Charette recently wrote one about Windham and gave it to a local schoolteacher.

Some days are better than others, and when they are, I try to make the most of them, Charette said.

He thinks about his musical legacy, pondering what its meant to himself and the thousands of children hes sung songs with.

Thats something Ive wondered, Charette said. Will this just be time that was taken up? Will they really remember any of it?

As news of his retirement spreads, hes getting his answer.

Cards, letters and Facebook messages are starting to pour in. People tell him about the impact his music had on their lives and now on their childrens lives.

He performed at my school all the time. I had Ricks records on my Christmas list in the 80s when I was a kid, said Heather Hilton, who grew up in Limington. Last year his downloads were on my sons wish list.

Hilton said her 5-year-old son especially likes Charettes epic song Where Do My Sneakers Go at Night? Hiltons mother, an elementary school teacher, still plays Charettes songs in her classroom and said her pre-K students still love them.

One card Charette received this month reads: From my birthday party in kindergarten, to Baxters first concert, youve made us smile throughout the years. Thank you for your wonderful gift of music. Your songs will live on. You will be missed.

It came with a smiling family portrait and was signed, Allyson, Baxter and Tristan.

After his final concert, one little girl waited in line to meet Charette. When it was her turn, she handed him a crinkled drawing of a snowman. It was signed, in pencil, From Athena.

I dont think its sunk in, yet, Charette said, looking at the drawing and the card. Sometimes, I beat myself up. I wish I could do more. Then, I have to remind myself to feel good about the things Ive already done.

Clark thinks Charettes music will be around long after both of them are gone. He points out that I Love Mud and Alligator in the Elevator are so familiar in the kid world, that many people mistake them for traditional folk songs in the public domain.

That seems to suit Charette just fine.

If I had to sum up the whole thing, Im just so gratified that Ive had this run, this experience, Charette said. Its always been the words and the music and the kids.

This story appears through a media sharing agreement with Bangor Daily News.

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What are the chronic complications of diabetes?

These diabetes complications are related to blood vessel diseases and are generally classified into small vessel disease, such as those involving the eyes, kidneys and nerves (microvascular disease), and large vessel disease involving the heart and blood vessels (macrovascular disease). Diabetes accelerates hardening of the arteries (atherosclerosis) of the larger blood vessels, leading to coronary heart disease (angina or heart attack), strokes, and pain in the lower extremities because of lack of blood supply (claudication).

The major eye complication of diabetes is called diabetic retinopathy. Diabetic retinopathy occurs in patients who have had diabetes for at least five years. Diseased small blood vessels in the back of the eye cause the leakage of protein and blood in the retina. Disease in these blood vessels also causes the formation of small aneurysms (microaneurysms), and new but brittle blood vessels (neovascularization). Spontaneous bleeding from the new and brittle blood vessels can lead to retinal scarring and retinal detachment, thus impairing vision.

To treat diabetic retinopathy, a laser is used to destroy and prevent the recurrence of the development of these small aneurysms and brittle blood vessels. Approximately 50% of patients with diabetes will develop some degree of diabetic retinopathy after 10 years of diabetes, and 80% retinopathy after 15 years of the disease. Poor control of blood sugar and blood pressure further aggravates eye disease in diabetes.

Cataracts and glaucoma are also more common among diabetics. It is also important to note that since the lens of the eye lets water through, if blood sugar concentrations vary a lot, the lens of the eye will shrink and swell with fluid accordingly. As a result, blurry vision is very common in poorly controlled diabetes. Patients are usually discouraged from getting a new eyeglass prescription until their blood sugar is controlled. This allows for a more accurate assessment of what kind of glasses prescription is required.

Kidney damage from diabetes is called diabetic nephropathy. The onset of kidney disease and its progression is extremely variable. Initially, diseased small blood vessels in the kidneys cause the leakage of protein in the urine. Later on, the kidneys lose their ability to cleanse and filter blood. The accumulation of toxic waste products in the blood leads to the need for dialysis. Dialysis involves using a machine that serves the function of the kidney by filtering and cleaning the blood. In patients who do not want to undergo chronic dialysis, kidney transplantation can be considered.

The progression of nephropathy in patients can be significantly slowed by controlling high blood pressure, and by aggressively treating high blood sugar levels. Angiotensin converting enzyme inhibitors (ACE inhibitors) or angiotensin receptor blockers (ARBs) used in treating high blood pressure may also benefit kidney disease in patients with diabetes.

Nerve damage from diabetes is called diabetic neuropathy and is also caused by disease of small blood vessels. In essence, the blood flow to the nerves is limited, leaving the nerves without blood flow, and they get damaged or die as a result (a term known as ischemia). Symptoms of diabetic nerve damage include numbness, burning, and aching of the feet and lower extremities. When the nerve disease causes a complete loss of sensation in the feet, patients may not be aware of injuries to the feet, and fail to properly protect them. Shoes or other protection should be worn as much as possible. Seemingly minor skin injuries should be attended to promptly to avoid serious infections. Because of poor blood circulation, diabetic foot injuries may not heal. Sometimes, minor foot injuries can lead to serious infection, ulcers, and even gangrene, necessitating surgical amputation of toes, feet, and other infected parts.

Diabetic nerve damage can affect the nerves that are important for penile erection, causing erectile dysfunction (ED, impotence). Erectile dysfunction can also be caused by poor blood flow to the penis from diabetic blood vessel disease.

Diabetic neuropathy can also affect nerves to the stomach and intestines, causing nausea, weight loss, diarrhea, and other symptoms of gastroparesis (delayed emptying of food contents from the stomach into the intestines, due to ineffective contraction of the stomach muscles).

The pain of diabetic nerve damage may respond to traditional treatments with certain medications such as gabapentin (Neurontin), phenytoin (Dilantin), and carbamazepine (Tegretol) that are traditionally used in the treatment of seizure disorders. Amitriptyline (Elavil, Endep) and desipramine (Norpraminine) are medications that are traditionally used for depression. While many of these medications are not indicated specifically for the treatment of diabetes related nerve pain, they are used by physicians commonly.

The pain of diabetic nerve damage may also improve with better blood sugar control, though unfortunately blood glucose control and the course of neuropathy do not always go hand in hand. Newer medications for nerve pain include Pregabalin (Lyrica) and duloxetine (Cymbalta).

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9 Symptoms of Type 1 & Type 2 Diabetes: Complications ...

Diabetes is a condition where your body either does not produce enough insulin or it is unable to use the insulin that it produces effectively. Insulin is a hormone that regulate your blood sugar levels. Uncontrolled diabetes can lead to many chronic health problems that can, at times, be fatal. The World Health Organisation says that diabetes can be treated, and its consequences avoided or delayed with diet, physical activity, medication and regular screening and treatment for complications.

Here, we reveal the best diabetes tips to follow in 2020. With our tips, you can save your self from a lot of adverse complications and live a long and healthy life.

If you are overweight, try to come down to your ideal body weight. Maintaining your body weight will help you to keep your blood sugar levels under control. If you think it will help, consult a nutritionist or your doctor. Hey will be able to guide you on the right path.

Add a lot of fruits and vegetables to your diet. Have fibre rich foods and avoid processed and sugary foods. Eat whole grains and legumes. Keep away from alcohol and stop smoking. All this will boost your overall health and also help you to keep your diabetes in check.

This test will help you know your average blood sugar level for the past 2 to 3 months. This will go a long way in helping you to formulate a plan to check your sugar levels. Seek an appointment with your doctor and get this test done. You should ideally do this twice a year. It will help you know if you are on the right track.

Heart diseases is a common complication of diabetes. And, blood pressure has a direct impact on heart diseases. So, it is essential to keep blood pressure levels under control. Go for regular check -ups and take prescribed medications for blood pressure.

This will improve overall fitness and health. It will help you lose weight and control cholesterol and blood pressure. Try to squeeze in at least 30 minutes of exercise e very day. Anything that increases heart rate will help.

Published : December 27, 2019 2:16 pm | Updated:December 27, 2019 2:30 pm

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Diabetes tips 2020 for a fit and healthy life - TheHealthSite

When you think about your preride prep, chances are, the coffee is just as important as the gels or energy bars you stash in your pockets. Which is good, because the health benefits of coffee, including a decreased risk of certain cancers, dementia, and stroke, are widely known. And while there is evidence that a cup of joe can also protect against the development of type 2 diabetes, new research out of Sweden found that the way you make your coffee might play a bigger role in the diseases prevention than previously thought.

In the study, published in the Journal of Internal Medicine, researchers looked at data from 421 participants in the Vsterbotten Intervention Program (1991 to 2005) who, after about seven years, developed type 2 diabetes and compared them to 421 participants who stayed healthy.

They looked at specific biomarkers in the participants blood samples (that were frozen from the Vsterbotten Intervention Program) and found that those who drank two to three cups of filtered coffee a day were 60 percent less likely to develop type 2 diabetes than those who drank only one cup of filtered coffee a day. However, drinking unfiltered coffeeboiled, K-cups, or French press, for examplehad no effect on type 2 diabetes risk.

So whats the deal? While researchers dont know for sure, the compounds in coffee that are known to elevate your blood lipid and homocysteine (an amino acid) levelswhich could lead to type 2 diabetesget captured in the filter paper and dont actually make it into the coffee you end up drinking, according to Rikard Landberg, Ph.D., study coauthor and head of the Division of Food and Nutrition Science at Chalmers University of Technology.

While this may seem alarming, Landbergs takeaway is still a positive one: Coffee isnt detrimental to your overall health. Intake of two to three cups per day could make a significant contribution to a healthy lifestyle for prevention of type 2 diabetes, he told Bicycling.

[Find 52 weeks of tips and motivation, with space to fill in your mileage and favorite routes, with the Bicycling Training Journal.]

While this specific study found that filtered coffee may be best for prevention, coffee, in general, contains chromium, which helps your body utilize insulin (a hormone that regulates your blood sugar).

So if you have a family history of diabetes or simply want to reduce your chances of developing it later in life, go ahead and sip a cup for a jolt of caffeine in the morning as well as an afternoon pick-me-up. Itll do more than just wake you up.

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Could the Way You Make Your Coffee Impact Your Health? - Bicycling

DexCom, Inc. has partnered with Tandem Diabetes Care in the UK,Sweden,Italy, andSpainto distribute the Dexcom G6 CGM System integrated with the Tandem Diabetes Care t:slim X2 insulin pump for people with diabetes.

Tandems t:slim X2 insulin pump with Basal-IQ technology uses Dexcom G6 CGM readings to predict glucose levels 30 minutes ahead and suspend insulin delivery when glucose is predicted to go low.

Insulin delivery resumes as soon as sensor glucose values begin to rise. The use of the integrated system reduced the time spent below 3.9 mmol/L (70 mg/dL) by 31 percent compared to the use of a CGM-integrated pump without automated insulin suspension1.

Combining the Dexcom G6 with Tandems t:slim X2 insulin pump will meaningfully improve diabetes management. Not only does the system eliminate the need for fingersticks, but it also helps patients reduce the frequency and duration of low-glucose events, saidErik Bjorkman, Dexcoms General Manager for EMEA.

Also, with the Dexcom G6 app, users can share their glucose information with up to five people. Whether you are a parent of a child with diabetes or an adult, the Dexcom G6 lets you seamlessly keep track of glucose levels and enables the users care team to remotely monitor their loved ones for extra peace of mind.

The t:slim X2 insulin pump with Basal-IQ technology, combined with the Dexcom G6, presents a meaningful advancement in the automated insulin delivery category, offering people with diabetes a simple-to-use system that predicts and helps prevent lows with zero fingersticks, saidBrian Hansen, executive vice president and chief commercial officer for Tandem Diabetes Care.

Some of the Dexcom G6 features include:

The CE Marking confirms that the G6 system meets the Essential Requirements of the Medical Device Directive MDD 93/42/EEC as amended by 2007/47/EC.

The powerful and ground-breaking new system is also the first CGM system to receive the US Food and Drug Administrations (FDA) De Novo classification.

With this new classification, the Dexcom G6 CGM system is indicated for use as both a stand-alone CGM and for integration into automated insulin dosing (AID) systems.

For more information on Dexcom G6, visitwww.dexcom.com/global.

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Dexcom Partners With Tandem Diabetes Care on Insulin Pump in Parts of Europe - dLife.com