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The Reality of 3-Parent Babies – Parentology

November 12th, 2019 4:44 pm

Start talking about 3-parent babies and thoughts may turn to science fiction. But, the technology to create a so-called 3-parent baby has been available since the 1990s; it just hasnt been put to use much, or studied.Thats about to change, as the technology has been revived and refined.

The updated technique, called mitochondrial replacement therapy, is being used in conjunction with In vitro fertilization (IVF), both as a way of avoiding some genetic diseases, and a method for ensuring IVF implantation success. The results for the latter havent been promising. However, with little tracking or longterm studies, the repercussions for babies born through this technology are unknown.

Through technology, a 3-parent baby has the DNA of a third person (another woman) added through IVF.

Originally, Dr. Jacques Cohen came up with a cytoplasm transfer in the late 1990s. The procedure used the cytoplasm (the material inside a cell, excluding the nucleus) of a donor egg injected into the host egg, and then fertilized. It produced a zygote that had mitochondrial DNA from the donor and nuclear DNA from the host parents.

According to Nu Sci Mag, Dr. Jacques Cohen reported in his book, Human Preimplantation Embryo Selection, the creation of 17 babies by this procedure, of which one was miscarried, and another was aborted.

The other 15 babies, unfortunately, werent tracked to learn the longterm implications of the DNA mix.

When the FDA [Food and Drug Administration] shut down the practice of cytoplasm transfer in 2001, labeling it a biological product and therefore within their domain, the clinic of Dr. Cohen lost the funding and support to pursue follow-up studies on the 15 other chimeras, Nu Sci reported.

So, while these babies dont exactly have three parents, they do have extra DNA from an additional party besides their host parents. Living things that contain such extra, genetically distinct DNA are known by another name: chimeras.

Chimeras do also occur naturally. A form of chimerism termed tetragametic occasionally (the American Journal of Medical Genetics estimates as many as 8% of fraternal twins have this) occurs when non-identical twins share a blood supply before birth. It can also occur with vanishing twin syndrome, in which one baby is born, but has cells from its now vanished sibling.

Another type of chimerism can happen when a patient receives a blood marrow transplant, then produces blood cells with DNA different from their original DNA. And, mothers often carry cells from the babies they carried, even years after their children are born.

Because chimeras are rare, they remain relatively unstudied. Chimeras born through mitochondrial replacement therapy are even rarer. The implications, both for the health of the baby and the genetic load down the germline, remain mysterious.

One of the justifications for implementing this new, improved fertility technology is to help implantation. Many women undergoing IVF endure two or more expensive and harrowing cycles of it. Ensuring implantation on the first try is a laudable goal.

A new study out of Ukraine suggests it doesnt work so well. There are only two clinics worldwide performing the 3-parent procedure (its currently banned in the US), and the study results, presented at a meeting of the American Society of Reproductive Medicine in Philadelphia, showed only one in 109 procedures led to a baby.

One Zero Medium reported that US experts are negative on the 3-parent baby efficacy for implantation.

Dr. David Keefe, an obstetrician-gynecologist at NYU Langone Health, told One Zero Medium the results are evidence that faulty mitochondria are not to blame for the quality of a womans eggs or infertility. They basically point out that it doesnt work.

Keefe suggests that tried-and-true options, like egg donation and surrogacy, are still the best bets if traditional IVF doesnt work.

The real justification for the procedure might be trying to avoid genetic diseases by adding different DNA into the equation. A baby born through what some US doctors term mitochondrial donation (the procedure was performed in Mexico) was born free of a familial disease called Leigh Syndrome, which always leads to the death of the infant. The family had already lost two children and had suffered four miscarriages because of the disorder.

The result is a baby with 0.1% of their DNA from the donor (mitochondrial DNA) and all the genetic code for things like hair and eye colour from the mother and father, the BBC reported.

Unfortunately, the parents also refused to have their baby tracked. This is problematic, because very little is known about the future health consequences of the procedure.

Mitochondria might be powerful, but theyre also involved in metabolic, immune, neural, and psychiatric function. Earlier this year, researchers published a paper showing that mitochondrial DNA is closely tied to the DNA in the nucleus, meaning it might not be possible to use just any egg donor. A mismatch could cause health problems for the child later in life, Keefe told One Zero Medium.

A recent article in Nature pointed out that scientists, because of lack of tracking and very low sample sizes in existing research, are still in the dark about the impact on babies born from a 3-parent situation.

Scientists dont know what amount of diseased mitochondria would cause noticeable symptoms, or even disease, in a child created using genetic material from two women, Nature reported. But studies in mice have shown that mixtures of mitochondria can result in neurological disorders or metabolic conditions.

Nu Sci MagOne Zero MediumNatureBBCScience Mag

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The Reality of 3-Parent Babies - Parentology

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Washington State’s Veterinary Association Announces Annual Award Winners – NBC Right Now

November 12th, 2019 4:43 pm

SNOQUALMIE, Wash., Nov. 12, 2019 /PRNewswire/ --The Washington State Veterinary Medical Association (WSVMA) held the Pacific Northwest Veterinary Conference in Tacoma, Wash., Sept. 27 Sept. 29. Veterinarians, veterinary staff, and citizens were honored at WSVMA's award ceremonies on Friday, Sept. 27.

Dr. Christine Wilford, veterinarian at Island Cats Veterinary Hospital in Mercer Island, Wash., received the 2019 Veterinarian of the Year Award. The award is presented in recognition of an outstanding career in veterinary medicine and contributions made to their practice, stakeholders, and other service directly benefiting their community. Dr. Wilford is a consummate, caring, and dedicated professional who created the national model to address the free-roaming cat reproduction and resulting kitten mortality through her founding of the Feral Cat Spay/Neuter Project, based in Lynnwood, Wash. She also served the Western Washington veterinary community through service in the Puget Sound Veterinary Medical Association as president and chair of their long-time, high-quality continuing education program.

Dr. Bryan K. Slinker, interim Provost of Washington State University (WSU) and former Dean of WSU's College of Veterinary Medicine, received the 2019 Distinguished Achievement award. The award was presented to recognize Dr. Slinker's dedication and outstanding contributions to the veterinary profession and Washington veterinarians through multiple accomplishments, including the work of the Paul G. Allen School to eliminate rabies by 2030, growing the College through new departments and capital projects, enhancing training for veterinary students by developing partnerships with humane societies, and establishing a One Health partnership with Univ. of Washington to provide side-by-side healthcare for people with pets who are experiencing homelessness.

The Clinical Simulation Center Team at Washington State University College of Veterinary Medicine was awarded the 2019 Faculty Member of the Year Award. The Center is led by Dr. Julie Cary and team members Dr. Robert Keegan and Lethea Russell, LVT. The Clinical Simulation Center includes experiential, simulation training in clinical communication, basic surgical skills, anesthesia and critical care activities, and ultrasound and endoscopy diagnostic skills.

Jess Hanson, licensed veterinary technician at Olympia Veterinary Specialists The Cancer Center, received the 2019 Distinguished Veterinary Staff Award. Mr. Hanson is recognized for his outstanding animal handling skills, exceptional technical skills, compassionate and educational interactions with animal families and staff, and his unparalleled high level of staff leadership.

Veterinarians, technicians and staff from the organization Feral Cats Spay/Neuter Project (FCS/NP), Lynnwood, Wash., were presented the 2019 WSVMA Humane Animal Welfare Award in recognition of their exemplary service to the organization and the community. FCS/NPwas the first free standing clinic that is dedicated to providing free spay/neuter surgery for free-roaming cats in a safe, high quality, humane environment.

Jay Jones, long-tenured professional at Hill's Pet Nutrition in Kent, Wash., received the 2019 Allied Industry Partner Award in recognition of his quiet, yet dedicated and faithful service to Washington veterinarians and their patients.

The WSVMA is a statewide, not-for-profit, professional organization for the benefit of veterinary medicine. The WSVMA has over 1,800 members, representing veterinarians, veterinary students and a broad spectrum of veterinary practice. The Association's mission is to "advance the cause of veterinary medicine to better the lives of those touched by it." Visit the WSVMA Web site, http://www.wsvma.org, to learn more about the association, veterinary medicine, and animal care.

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Washington State's Veterinary Association Announces Annual Award Winners - NBC Right Now

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Nagaraja named Distinguished Veterinary Microbiologist of the Year – Manhattan Mercury

November 12th, 2019 4:43 pm

T.G. Nagaraja, distinguished professor of veterinary microbiology at Kansas State University, has been named the 2019 Distinguished Veterinary Microbiologist of the Year by the American College of Veterinary Microbiologists. This award was presented at the organizations annual meeting Nov. 4 in Chicago.

I am truly humbled by the award, Nagaraja said. It is special because this recognition is from my peers. I have had a lot of help in my research career some outstanding graduate students, very good laboratory help and excellent collaborators.

Nagaraja is a member of the diagnostic medicine and pathobiology department faculty in the K-State College of Veterinary Medicine. His appointment is 70% research and 30% teaching. His research expertise is in gut microbiology, focused primarily on the role of rumen microbes in function and dysfunction of the rumen, and on foodborne pathogens, particularly Shiga toxin-producing Escherichia coli and salmonella in cattle. His research is a blend of basic and applied studies and involves collaborative interactions with epidemiologists, molecular biologists, pathologists and ruminant nutritionists.

Included in Nagarajas teaching responsibilities are veterinary bacteriology, and mycology lecture and laboratory for sophomore Doctor of Veterinary Medicine students, ruminant digestive physiology for freshman Doctor of Veterinary Medicine students and two graduate courses, rumen metabolism and rumen microbiology. Additional responsibilities include serving as the College of Veterinary Medicines director of the graduate programs in pathobiology and veterinary biomedical science.

Nagaraja and his graduate students have been responsible for several seminal findings, including describing that the feeding of distillers grain was positively associated with prevalence of E. coli O157, a major foodborne human pathogen, in cattle. In addition, he and his associates were the first to identify and describe the role and importance of the toxin leukotoxin, produced by Fusobacteroum necrophorum that causes liver abscesses in cattle. Nagarajas group also developed an experimental model to study liver abscess in cattle by inoculating F. necrophorum via ultrasound-guided, percutaneous catheterization of the portal vein, which allowed for the demonstration that leukotoxinis can be used to protect the animal against liver abscesses. This led to the development of a U.S. Department of Agriculture-licensed leukotoxoid-based vaccine to prevent liver abscesses in feedlot cattle.

In addition, Nagaraja has developed experimental models to induce bloat and acidosis, two major digestive problems in cattle. The experimental models were instrumental for testing and identifying new compounds to control bloat and acidosis in feedlot cattle, describing the effects of antibiotics like lasalocid, monensin and virginiamycin on ruminal microbes and fermentation to better understand their modes of action.

Nagaraja and his associates have produced more than 216 peer-reviewed articles, 115 invited national and international presentations, 19 book chapters and 20 review papers and symposium proceedings on food safety research. As a mentor, he has supervised 19 doctoral students, 21 masters students and four Master of Public Health students. His work has resulted in eight U.S. patents.

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Nagaraja named Distinguished Veterinary Microbiologist of the Year - Manhattan Mercury

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How does geospatial mapping protect Pennsylvania’s pigs from disease outbreaks? – The Pig Site

November 12th, 2019 4:43 pm

Tell a swine or poultry producer that their animals are sick and the first question they ask is, How?

Thanks to researchers at the University of Pennsylvanias School of Veterinary Medicine (Penn Vet), producers can now get an answer to that pressing question fast or even stop disease from encroaching past their property lines altogether.

Run by Penn Vets Dr Meghann Pierdon, the programme relies on geospatial information systems (GIS) to pinpoint current and emerging disease hotspots, share information about outbreaks with producers, and strategise community approaches to control potentially devastating diseases. Pierdon uses the GIS data to update a secure website with a map that illustrates, in near-real time regions, where pigs or birds have tested for disease and identify areas that may be at risk. The database is updated quarterly to be sure everything is accurate and communication is open to producers.

In 2012, nearly a quarter of the swine monitored by Penn Vets swine disease mapping programme, called the Pennsylvania Regional Control Program (PRCP), were on farms testing positive for disease. Since participating in the PRCP, which is operated by Pierdon and funded by the Pennsylvania Pork Producers Council, that number has declined to 15 percent; 17 percent if Ohio and Indiana are included.

As a result of its success, industry participation in the PRCP has doubled to include more than 100 farmer, hauler, feed and genetics companies and veterinarian members across the Commonwealth.

The idea is to provide usable data so farmers can take the information and make informed production decisions.

For example, we can set up protected zones where we only want negative pigs, says Pierdon. Producers can then make appropriate decisions based on that information, such as, being careful if buying feeders from infected areas or preventing a feed truck that was on a farm with active disease from going directly to their farm to help cut the disease spread."

Several years ago, the first swine disease Pierdon tracked was porcine respiratory and reproductive syndrome (PRRS). Today, an emerging pathogen, porcine epidemic diarrhoea virus (PED), has caught her attention.

Most of the GIS data is drawn from Pennsylvania farms but, since neither commerce nor disease heed state lines, she also gathers information from Maryland, Delaware, and New Jersey.

On the pig side, a vet or producer fills in a template with basic data like the farms address, where the pigs came from and where they will go next.

The PRCP has been instrumental in helping the industry understand the scope and impact of this new PED disease and in implementing the best biosecurity measures to stop the spread of the deadly virus, she said.

While it is endemic, PRRS is preventable, Pierdon says. The idea is to decrease the number of farms that are impacted by an outbreak. Then a producer can clean it up and not have to worry that it will come back, she adds.

Most recently, Pierdons GIS mapping has played an integral part in safeguarding Pennsylvania poultry farms from the recent outbreak of Coryza in the Commonwealth. Similar to a head cold in humans, coryza is a bacterial contagious disease of poultry that presents with secretion of mucus deposits in the mouth and throat. The implications for production on farms whose birds have contracted the disease, however, are serious.

It cropped up in December 2018 and progressed in number of cases until late Spring, says Pierdon. While it slowed this summer, she is noticing and mapping an uptick in the number of cases now.

In addition to providing on-farm outreach and support, Penn Vet also works with federal and state agencies. While government tracks foreign disease threats like foot-and-mouth, Pierdons focus is on monitoring diseases that loom as a threat to farmers but are not reportable to the government. It really is all about improving and implementing biosecurity, she says, adding that the data she gathers helps agencies understand how industry is structured.

There have also been what Pierdon calls nibbles of interest in applying her GIS programme to help safeguard other agricultural industries, mainly aquaculture and honeybees.

No matter where the system is deployed, the main objective is to decrease the amount of disease spread and give producers control over safeguarding their farms or operations.

Were not just looking to respond to the disease in the moment, but ultimately, provide biosecurity solutions that can protect our animals, our people, and our environment from the next big, bad bug.

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How does geospatial mapping protect Pennsylvania's pigs from disease outbreaks? - The Pig Site

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Veterinary Webinar Provides Education about CBD Products for Pets – CBD Today

November 12th, 2019 4:43 pm

An educational webinar for veterinarians about CBD products and use of cannabidiol (CBD) products for pets with various medical conditions was presented by Dr. Zac Pilossoph, chief medical officer for Cansultants, Inc.

Sponsored by the National Cannabis Industry Association (NCIA) on its YouTube channel, Dr. Pilossoph also discussed the status of medical cannabis recommendations for veterinarians in the U.S. The presentation was titled, The Cannabis Pet Industry: Whats to Know and Whats for Show.

The presentation started off with a primer on the endocannabinoid system, which Pilossoph said, should be thought of as a homeostatic regulator system found in humans and chordates, or animals with a spineincluding animals such as horses, birds, and reptiles that often are overlooked when CBD treatment for pets is considered.

Dr. Pilossoph commented that one of the reasons he took up education around cannabis-based medicines and their use in veterinary treatment was because he felt frustration from not having learned about the endocannabinoid system earlier, and the lack of instruction available to medical students and doctors.

I felt frustrated, how Id never learned this in school, he explained.

Going on to cite published studies about the effects of CBD (and cannabis-based medicines), Pilossoph said there have been several studies, going back to the 1980s, that show cannabis had beneficial effects for several conditions including glaucoma, inflammation, and nausea, as well as having proven anti-bacterial properties.

In veterinary medicine, studies of cannabis- or hemp-based treatments are hard to find, but a wealth of anecdotal evidence has presented, as pet owners attest to the results they have seen when self-treating pets with CBD.

Pilossoph noted that such a trend among pet owners, by itself, should encourage more clinical studies to be conducted to identify the beneficial components in CBD (and other plant compounds). He added that a there have been studies conducted on dogs that indicated CBD could provide anti-inflammatory benefits for osteoarthritis and seizures.

Other plant compounds that work in synergy with cannabinoids create the entourage effect, Pilossoph said further. Terpenes and flavonoids, he said, seem to enhance the effects of cannabinoids in cannabis- and hemp-based medications.

The entourage effect exists, he said, which would suggest that full-spectrum formulations might provide greater therapeutic benefits.

Pilossoph hoped that product manufacturers would harness the power of raw hemp, as a resource for full spectrum CBD extract that would also contain only trace amounts of THC, or tetrahydrocannabinol, the psychoactive compound in cannabis. Hemp contains less than 0.3 percent levels of THC.

He made the point that while products might vary between human and veterinary, the endocannabinoid system functions similarly for all species. Products labeled pet CBD, he explained, contained the same CBD extract as what is used in human products. Variations in formulations, he said, typically had more to do with ingredients added to make treats and tinctures palatable to animals.

He specifically mentioned veterinary CBD tincture PetCBD as the only formulation that he knew of that had been developed by a veterinarian, Dr. Tim Shu. Dr. Shu, who is no longer actively practicing, is the founder and chief executive officer at PetCBD.

However, Pilossoph stressed that he could not recommend specific products and that his information should be considered strictly educational.

The American Veterinary Medical Association (AVMA) has issued a three-page statement outlining its position on veterinarians recommendations for CBD use with pets. Pilossoph summed it up by saying that the association suggested avoiding making recommendations for CBD use until the Food and Drug Administration (FDA) establishes product quality control regulations.

Pilossoph offered a basic, stepwise outline to help chose CBD products for pets:

Dr. Pilossoph also warned pet owners to avoid giving pets edible treats (with or without CBD) produced for humans mostly due to ingredients in human products that might be harmful for animals, like chocolate or artificial sweetener Xylitol. He singled out Xylitol as being potentially fatal for pets.

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Veterinary Webinar Provides Education about CBD Products for Pets - CBD Today

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Why we need to be prepared for African Swine Fever – Jill Lopez

November 12th, 2019 4:43 pm

The World Organization for Animal Healthrecently announcedthat 25% of the worlds pigs are expected to die from African swine fever (ASF), a highly contagious disease that causes hemorrhages in pigs. ASF has not yet made its way to the United States.

Dr. John Deen, a professor in theCollege of Veterinary Medicineat the University of Minnesota reports, that African Swine Fever has caused a major realignment of animal agriculture. It has spread throughout China and neighboring countries, resulting in less pigs and pork. More than 60% of the worlds pigs were in these countries, with pork being the preferred meat for consumption. Estimates of a 50% reduction in pigs in Southeast Asia are due to pigs killed by the disease, as well as farmers liquidating their herds out of fear of infection.

According to Deen, rebuilding the swine herd will not only take time but a transformation in the ways that pigs are reared.

The University of Minnesota's College of Veterinary Medicine is helping the Chinese industry identify methods to protect and expand their herds.

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UMD researchers identify liver cells that could be key for fighting fungal infections – The Diamondback

November 12th, 2019 4:43 pm

Meiqing Shi motioned toward the window of his first floor office, pointing to the trees and plants outside of the University of Marylands veterinary medicine center. Fungi, he said, is all around out there.

In the dirt here, in the park, the veterinary medicine professor said. [Its] everywhere.

For many, fungus isnt dangerous the immune system can kill it or it might just sleep in the lungs. But for those with a compromised immune system, such as the elderly or people with HIV, fungus introduced to the body can cause an infection and potentially be fatal.

Shi is part of a team at this university that discovered a mechanism in the liver that can inhibit the spread of fungi in the bloodstream. They uncovered that cells in the liver, called Kupffer Cells, can engulf the fungal cells and filter it from the bloodstream.

The liver is already known to be an organ that supports digestion and metabolism, said Donglei Sun, the first author on the paper, which was published last month. But scientists in his field are also beginning to recognize the organs importance to the immune system.

Past research suggested the liver can filter bacteria and viruses, Sun said. But the teams recent discovery proves that the liver can also engulf fungi.

Whether its coming from the lung and disseminating into the blood or if its systemic and just already in the blood, the ability for the liver to kind of clear everything is just really important, said Ashley Strickland, a doctoral student and member of the research team.

[Read more: UMD researchers identify liver cells that could be key for fighting fungal infections]

Sun said that the use of intravital microscopy was key to identifying this liver capability. Rather than using a static slide, this tool allows scientists to see the cells in motion, using a window implanted in the live animal to image it in real time.

We are using a unique technique, and we are able to show exactly how the cells are moving, how the cells are interacting with the pathogen, Sun said.

The researchers were able to watch cell activity in a live mouse that they put to sleep. A supplementary video attached to the research paper showed that the Kupffer Cells captured most fungal cells.

Similar experiments might be conducted in-vitro in a culture dish or test tube which can be somewhat artificial, Strickland said. Intravital microscopy, though, offers something more realistic, she said.

You dont really get to see the dynamic and the kinetics and how it really is, Strickland said. You can theorize and you can interpret but you dont actually know.

[Read more: Takoma Park gas station becomes the first in the country to go all-electric]

Strickland observes the effects of fungal infections in mice. When theyre infected, their brains become dome-like because of all of the inflammation, she said

Cryptococcus neoformans, one of the fungi the team researched, targets the brain, she said. And once it makes its way there, it can spread quickly.

That inflammation is just not good for the brain as an organ, she said. If its not treated, its I think 100 percent fatal.

Now that the team has discovered the livers ability to fight fungal infections, Shi said the next step is figuring out how to harness that power to help protect people who are at risk and have weakened immune systems.

We know that theres a mechanism there, Shi said. How can we take advantage [and] use the mechanism for defense?

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Veterinary Software Market Size is projected to reach $728 million by 2025 | OGAnalysis – The Denton Chronicle

November 12th, 2019 4:43 pm

The $410 million global Veterinary Software Market is set to emerge rapidly, building synergies between IT, internal medicine and animal welfare, notes Ayesha Salma in the new report, research analyst at OGAnalysis.

Management suite of animal hospitals and veterinary clinics are increasingly seeking different Veterinary Software products to ease the task of maintaining electronic medical records, treatment procedures, appointments and other hospital administration protocols.

Huge research and development investments across veterinary software markets including development of innovative solutions and IT services will shape the medium term outlook of veterinary software market. For instance, IDEXX Laboratories, an American veterinary diagnostics company invests around $120 million on R&D activities.

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Growing incidence rates of diseases among livestock, growth in pet animal owners and welfare societies will be the key contributors to global Veterinary Software Market size over the forecast period to 2025.

On the other hand, high costs involved in deployment of veterinary software and shortage of skilled veterinary personnel act as veterinary software market restraints.

User-friendly veterinary software products witness huge attention from vendors and consumers

A significant volume of veterinary software consumers and vendors are depicting interest in user-friendly software products. Practice management software modules with cloud-based delivery mode hold major market value amid benefits of single platform to access medical information by researchers, practitioners and patients. Major companies involved in cloud based solutions are IDEXX Laboratories, VETport, ezyVet Limited and Carestream.

Further, marketing strategies practiced by cloud-based PMS vendors like VETport such as free trials & zero cost installation are penetrating markets with relative ease.

Browse Veterinary Software Market Research Report @ https://www.oganalysis.com/industry-reports/216518/veterinary-software-market

Ongoing Strategic partnerships and collaborations with research organizations and universities

Veterinary software companies are primarily focusing on developing joint ventures and collaborations with research universities for diversifying their product portfolio.

In July 2019, Simulations Plus, Inc. has entered into a new 5 years Research Collaboration Agreement with the USFDA Center for Veterinary Medicine.

In May 2018, Cornell University College of Veterinary Medicine signs partnership agreement with ezyVet to use the cloud-hosted veterinary PMS solution.

Top 10 companies contributing towards market growth include Animal Intelligence Software, Brittons Wise Computers, ClienTrax, Carestream, FirmCloud Corporation, Henry Schein, IDEXX Laboratories, Patterson Companies, Timeless Veterinary Systems, and Vetter Software.

Rapid adaptation of veterinary software digital equipment is observed across hospitals, clinics and laboratories

End-users holding the major market share including hospitals, clinics and laboratories are increasingly adapting diverse ranges of digital software equipments to enhance diagnosis and support animal health programmes. For instance, Idexx Laboratories provides Catalyst blood chemistry equipment, VetLyte Electrolyte Analyzer, ProCyte CBC, UA Analyzer, SNAPShot, and SNAPPro to hospitals in North Dakota and the US.

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Government animal welfare policymakers support veterinary software market growth

Government animal welfare authorities are supporting the veterinarians and companies through incentives and stringent guidelines for promotion of veterinary software globally, which is anticipated to contribute significantly to the market growth.

World Society for the Protection of Animals (WSPA) works with the veterinary community to support animal health by providing funds for the development of high quality veterinary software equipments.

On regional scale, Americas and EU stand as market frontiers

The surging pet care market value and rising per capita animal healthcare expenditure across Americas and EU influences the veterinary software market growth. For instance, In US, the pet owners spend an average of about $140 per month on their pets with US pet insurance industry worth estimated to be nearly $2 billion by 2022.

As of 2018, an estimated 80 million European households owned a pet with anticipated market value for pet care products reaching 5.3 billion Euros, with United Kingdom as the peer market holders.

Further, presence of large number of trainers and practitioners across these regions contribute to long term market opportunity. According to the American Veterinary Medical Association, about 113,394 veterinarians are present in North America.

Related Reports

Veterinary Vaccines Market: https://www.oganalysis.com/industry-reports/217757/veterinary-vaccines-market

Veterinary Surgical Instruments Market: https://www.oganalysis.com/industry-reports/216519/veterinary-surgical-instruments-market

Animal Health Market: https://www.oganalysis.com/industry-reports/217681/animal-health-market

Small Animal Imaging Market: https://www.oganalysis.com/industry-reports/216476/small-animal-imaging-market

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Have you heard of variant Chinese pseudorabies? – National Hog Farmer

November 12th, 2019 4:43 pm

I'm not really a gambler, but I would be willing to wager you would be hard pressed these days to attend a swine industry meeting and not hear the words African swine fever. It's definitely top of mind for the global pork industry as it rightly should be. Scientists are now estimating that a quarter of the world's pigs could be wiped out from the highly contagious hemorrhagic viral disease.

However, when one of our industry's leading researchers on ASF transmission in feed took a break from discussing the virus at South Dakota State University's Swine Day to focus on another one that is concerning her, my ears perked up.

Pseudorabies is another virus Megan Niederwerder is allowed to work with at Kansas State University's biosafety level 3 facility and the assistant professor of diagnostic medicine and pathobiology in the College of Veterinary Medicine, says it's a variant strain of Chinese pseudorabies, HeN1, that has her worried.

"Historically, China has had classic pseudorabies which is what previously circulated in the United States until it was eradicated from U.S. commercial swine in 2004. But since 2011, a variant strain of pseudorabies emerged in China which seems to have higher morbidity, higher mortality," Niederwerder says. "They also detected it in herds that were vaccinated with the Bartha-K61 strain, which had historically protected pigs against pseudorabies."

In 2013, one of the first publications came out documenting this new variant strain of Chinese pseudorabies and soon after it emerged in about nine provinces in China. A more-recent publication shows that the variant strains can now be found in more than 20 provinces.

"The variant strain of pseudorabies virus seems to be spreading throughout China and the Bartha vaccine strain does not seem to be as protective against this variant strain of Chinese pseudorabies," Niederwerder says.

Niederwerder says there are risks that this new pseudorabies may be introduced into other parts of the world where nave pigs would be highly susceptible to disease and that there are concerns that pseudorabies has the potential to be considered a zoonotic pathogen.

"Pseudorabies is a herpesvirus. It can affect dogs and cats, many different mammalian species, but historically humans have been considered resistant to infection with sporadic cases reported," Niederwerder says.

Niederwerder says the emerging infectious disease should be on the global swine industry's radar and that the risks for virus introduction should be investigated for prevention strategies.

In addition to ASFV, HeN1 and classical swine fever are two viruses Niederwerder is currently studying at K-State on their ability to survive in feed ingredients subjected to environmental conditions simulating transoceanic shipment. She hopes to have that research published before the end of the year.

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Housing shortage addressed in public meetings with university, city, county officials – The Aggie

November 12th, 2019 4:43 pm

Representatives from UC Davis, city council, county board of supervisors hosted a yearly meeting on campus, special focus on student housing efforts

An annual public meeting between county, city and university representatives was hosted at the UC Davis Genome Center Auditorium on Oct. 17, during which officials discussed the measures currently underway to address a shortage of available housing in Davis. University officials delivered a follow-up presentation during the next city council meeting on Oct. 22.

The university was represented by Chancellor Gary May, Vice Chancellor for Finance, Operations and Administration Kelly Ratliff and Associate Chancellor Karl Engelbach, according to the meeting notes. Mayor Brett Lee and Mayor Pro Tempore Gloria Partida, as well as council members Lucas Frerichs, Dan Carson and Will Arnold, represented the city government, while supervisors Dan Saylor and Jim Provenza represented the county.

At the meeting, May delivered a presentation that both highlighted the universitys recent successes and cited efforts currently underway to build new student housing. May cited UC Davis recent rankings among other public universities in the U.S. including placing fifth in the country by the Wall Street Journal/Times Higher Education ranking, fourth by Money Magazine and 11th by US News. He noted that UC Davis continues to rank first in the world for Agriculture and Veterinary Medicine and that UC Davis Medical Center was ranked the number one hospital in Sacramento.

After touching on some of the administrations efforts to address mental health and food insecurity among students, May moved on to the subject of housing. According to Mays presentation, the university has set the goal of 6,000 new beds by 2025. In early November, the university released a report detailing the progress of each of its new housing developments toward meeting this goal.

Lee, representing the city, presented a table of data on the status of several pending, under-construction and completed housing developments in the city. The table included several student-oriented housing developments that had completed the planning review stage and were pending construction, including Nishi, Lincoln 40 and Davis Live. The pending developments would add 3,348 new beds to student housing. The chart also noted the recently completed Sterling 5th St Apt., slated to provide 540 beds by completion.

Lee also noted other major developments within the city that targeted individuals, families and members of the workforce. In total, completed and pending developments listed on Lees chart would add 4,567 new beds of available housing in the city upon completion. Lee said he expects all of the pending construction to be completed between two to five years from now, according to the Davis Enterprise.

A lot more housing will be hitting the market soon, Lee said, according to the Enterprise.

Supervisor Don Saylors presentation focused mainly on the countys participation in specific services offered on the UC campus, including CalFresh and mental health resources under the Mental Health Services Act.

He did note several projects that may improve the commute of off-campus students, including an improvement project on I-80 that seeks to reduce traffic congestion through Davis and the launch of the Causeway Connect bus project. This will institute fully electric buses traveling between the UC Davis campus and the Sacramento medical center, with additional limited stops in Davis and Sacramento. The projected is targeted to launch in April 2020.

During the Oct. 22 city council meeting, administrators from Davis delivered a follow-up report on the colleges finances, which paid special attention to how UC Davis plans to address some of the housing pressures posed during the on-campus meeting.

Megan Glide Villasenor, assistant director at UC Davis Shared Services Center, pointed to a goal set by UC President Janet Napolitanos 2016 Student Housing Initiative which sought to add 14,000 new available beds in student housing across the UC system. Villasenor said that the UC system had exceeded that goal, with a projected 15,161 new beds added system-wide by Fall 2020. UC Davis will have instituted 2,190 of that number, according to Villasenor.

Davis has actually been an integral part of reaching the target we set for the fall of 2020, Villasenor said.

After the administrators presentation, Lee stressed the importance of continued collaboration between the university and city officials to address housing issues in the city.

The goal here is to mitigate some of the impacts that the student population has, but we need to be smart about it and work in partnership, Lee said.

Written by: Tim Lalonde city@theaggie.org

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Homeless with HIV: A lack of housing makes a preventable disease deadly in Oregon – OregonLive

November 11th, 2019 11:46 am

Every month, Tim Menza receives reports about new HIV diagnoses and compares them to previous years. As a doctor and data analyst for the Oregon Health Authoritys sexually transmitted disease and HIV program, hes familiar with how the HIV epidemic has waxed and waned.

Oregon is four years into a five-year, federally sponsored program to end HIV transmission by testing vulnerable Oregonians, alerting them of their HIV status and providing them with treatment and preventative medication. Menza had been optimistic Oregon was on track to eliminate future HIV transmissions.

But a year ago, he noticed a troubling trend that Oregon was ill-prepared to tackle an HIV outbreak exacerbated to a deadly pitch by the harsh living conditions of the street.

While the uptick in new cases is driven by drug use, it is difficult to contain because of homelessness.

Few places nationwide have seen such a wave of new HIV cases as Multnomah County, where the number has more than tripled to 71 over the past two years. In this year alone, 37 people have been diagnosed close to equaling the total for 2016 and 2017 combined.

The virus has historically targeted marginalized communities, devastating an entire generation of gay men in the U.S. in the 1980s and 90s, and later taking hold in communities of color. But in the past few years, the outbreak has surged among intravenous drug users who are or who soon become -- homeless, and their sexual partners.

Public health officials have had to start envisioning their work as tied to the homeless services system, actively canvassing camps to seek out those who are sick. While health care providers have become homeless service providers, troubleshooting patients needs beyond medication.

People who have homes can fairly easily survive HIV, a pill taken once daily allowing them to live nearly symptomless. Yet it remains a potential death sentence for homeless people, who have their medication stolen, lack clean shelter facilities and suffer poor nutrition and sleep -- leaving their immune systems unguarded against the deadly virus.

A compounding factor

When Menza looked at the data a year ago, he found that across the state -- in both rural and urban areas -- new HIV cases were popping up among people who inject drugs and didnt have access to stable housing.

It wasnt necessarily a surprise. He had seen reports of syphilis and Hepatitis C rising in those populations often precursors to an HIV infection.

He knew the state needed to take immediate action, but the traditional path wouldnt work this time.

HIV cases among people who use heroin and methamphetamines jumped to 30% in the last two years, more than double the percentage of years before, according to state data.

Drug users typically separate themselves into social and sexual networks based on their drug of choice. But recently, those circles seemed to overlap more than ever. Officials say cheap, high-quality meth has flooded into the state over the past few years, a popular drug for people who live outside and want to stay up through the night to avoid being assaulted or robbed. The spike in meth use coincides with an existing opiate crisis, and many people have turned to using both the depressant and stimulant.

On top of that, Menza said that there is growing evidence that homelessness is a compounding factor.

Every time a campsite or group of people who use drugs together is dispersed through sweeps or clean-ups, the people there move and form new networks. Single-sex shelters split heterosexual couples up, making it hard to stay with one partner long-term.

That slowly extends the number of people who are capable of spreading the disease geographically and demographically.

A public health worker trying to contain an outbreak in a small group of people now must navigate ever-expanding networks.

If youre trying to do an intervention in a camp, Menza said, you have to work fast.

Taking healthcare to camps

In Multnomah County, many people who are homeless or on the brink of it receive HIV care from the publicly funded HIV Clinic, housed in the gleaming new health department headquarters near Union Station.

From that outpost, public health workers are adjusting how they mobilize around the HIV outbreak nearly on the fly.

Jaxon Mitchell leads the countys disease investigation team and field outreach. Hes used to tracking people down. Usually he can look up someones cell number or send them a message on social media. But that doesnt work with this outbreak.

To locate people, Mitchell and his team must search camps, scour social media profiles for clues and trace leads from hospitals and friends. Thats made even harder by strict health privacy laws that mean Mitchell often cant tell neighboring campers why he is looking for a specific person.

The rise in HIV -- and its accompanying diseases of syphilis, shigella, hepatitis A and C mean that Mitchell often receives test results for homeless people who went to an ER for short-term treatment but were discharged to the street before the results came back.

When he does find the person he is looking for, he often has to work quickly to identify anyone else who might be infected sexual partners or people that have shared needles and get them tested or into treatment.

Out of a van designed for such field work, the county offers on-the-spot medical help, testing and provides other necessities like clean socks, snacks and tampons.

The public health department has faced smaller scale outbreaks before. For instance, Mitchells team is dispatched when a homeless person is diagnosed with tuberculosis and they must make sure the patient takes several months worth of pills to contain it.

But this is a much larger undertaking than ever before.

Its all based on being able to find people, said Jennifer Vines, the countys deputy health director. Now suddenly were in a new situation of having to figure out how to use our tools when people are hard to find -- or not wanting to be found.

Training the front lines

In his role at the county, Chris Hamel must train service providers on how to talk to their clients and patients about getting tested for HIV.

He seeks out homeless service agencies, primary care doctors, detox centers, parole and probation officers anyone who might interact with people at risk of HIV to try to make that step easier.

County officials have found that if they can get someone who is newly diagnosed into HIV care within 30 days, they are more likely to stay in care long-term. So field workers try to keep in contact through the first few appointments.

Were trying our hardest now to go to people, Hamel said. But I would like to see us continue to build a public health system that people feel comfortable enough that they will come to us.

Public health workers face the challenge of being as focused on those who havent yet contracted HIV as they are on people with positive test results.

Pre-exposure prophylaxis, or PrEP, is a daily medication that is highly effective at preventing transmission of the disease. Mitchell and his team also track down everyone they can who might be in the orbit of a someone with HIV to make sure they have access to the medication.

Thats a new sell to many. The pill has largely been targeted at gay men because it works even without use of a condom. But state data shows a 600% increase in women getting syphilis a sure sign that HIV will parallel that rise.

In this outbreak, the people most at risk are women, sex workers and intravenous drug users who tend to be straight men -- all people who likely never considered needing the preventative medicine.

Its the art of public health, Vines said. Were thinking about the individual, but we also have to think about the persons social circle.

Hard to help

In 2014, Indiana had more than 200 cases among intravenous drug users in one county. Last year, West Virginia experienced 80 new HIV cases tied to intravenous drug use.

Officials are seeing the HIV resurgence across the country, but the West Coast is unique in its profound lack of housing affordable to sick or addicted people.

In 2018, a cluster of HIV cases in Seattle caught the federal governments attention. The outbreak was within a distinct group of people who hadnt before been a driving force among new cases: Heterosexual people who were homelessness and using intravenous drugs.

Twenty-one homeless people in Seattle were found to have passed around HIV sharing needles and sex. The cluster bumped King Countys rate of HIV among homeless heterosexuals who inject drugs by 286%. Months after the cluster was identified, seven of the 21 people were still not receiving HIV care.

The King County outbreak demonstrates how difficult it is to engage the most socially marginalized persons with medical care, said a U.S. Centers for Disease Control and Prevention report.

San Francisco has seen a steady increase in deaths among this growing population. Someone with HIV who is homeless is 27 times more likely to die than a person with HIV who is housed, said Elizabeth Imbert, the doctor who oversees a new private clinic at Zuckerberg San Francisco General Hospital.

The citys homeless people account for 14% of all new HIV diagnoses, despite making up only 1% of the citys population, according to the local public health department.

The hospitals Ward 86 served at the forefront of a burgeoning AIDS crisis in the 1970s. Now its launched the POP-UP Clinic, a program designed to get homeless people in the door and in treatment.

Imbert knew from local data that only one-third of San Franciscos infected homeless population has been able to lower the amount of HIV in their blood stream to the point where they cant transmit it anymore what health officials call viral suppression. That is well below the average rate of 74% for all people with HIV in San Francisco.

The hospital launched its own survey to find that of 1,200 patients, the amount of the virus in their body increased as their housing situation became more unstable. And, as the amount of virus in their body went up, the more they missed primary care appointments and ended up in the emergency room and urgent care.

So leaders of Ward 86 created a new way to treat those patients. They had to find a way to get sick people in the door who dont trust institutions like hospitals.

Ward 86 employs people who focus on non-medical needs in hopes that it will help patients stabilize enough to stay on their medication. They also work with housing specialists from the state health department and community organizations to connect patients to services and ask that those workers come into the health clinic to do so.

The clinic is open four hours daily on Monday through Friday, and patients dont need appointments to see a doctor. Currently, about 180 patients are eligible for the program, which targets people who have missed an appointment in the last year.

Once they do come in the door, they are offered financial incentives to keep coming. The hospital offers a $10 gift card for every week theyre in the program, a $10 gift card to have blood work done and $25 if the patient achieves viral suppression.

Nearly a year in, 60 people are enrolled. Most have started on medication and Imbert said that shes already seen some in the program whove had their virus become undetectable. About half of the patients come regularly, while a quarter visit a few times a week.

We are using essentially every resource in the city, Imbert said, to get them indoors, housed, on a waiting list.

-- Molly Harbarger

mharbarger@oregonian.com | 503-294-5923 | @MollyHarbarger

Visit subscription.oregonlive.com/newsletters to get Oregonian/OregonLive journalism delivered to your email inbox.

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November is not only known as the start of the holiday season, it’s also known for Open Enrollment – WZZM13.com

November 11th, 2019 11:46 am

GRAND RAPIDS, Mich. When it comes time to enroll in a health insurance plan, there are often many questions or misconceptions.

Dr. Kristen Brown, president of Mercy Health Physician Partners, stopped by to talk us through what Open Enrollment means and which details should not be overlooked.

Open enrollment is the period of time where you select your health insurance coverage. This is generally the only time, outside of a qualifying life event, when you can add or drop a coverage plan or make changes to your coverage.

The choices you select during open enrollment set up how you will be managing your health care in the coming calendar year. One of the important, but sometimes overlooked, pieces of open enrollment is selecting your Primary Care Provider.

Primary Care is a relationship with a health care provider that is focused on taking care of you with your whole well-being and health history in mind. They are your first contact for undiagnosed health concerns, as well as preventative and continuing care of medical conditions.

PCPs offer a variety of services from annual wellness visits to vaccines and minor surgical procedures. They will also refer you to specialty care when needed.

There are several types of Primary Care Providers what is the difference?

Primary Care can also be referred to as Internal Medicine, Family Medicine, Geriatric Medicine or Pediatric Medicine.

When choosing a provider, your goal should be to build a lasting relationship. This individual will be your first medical contact and the health provider who knows you best. Some things to consider while select your PCP include:

In-Network vs. Out-of-NetworkStart by referencing your health insurance coverage, which typically publishes a list of providers who are In-Network. These providers will offer the best rates and work seamlessly with your health insurance.

Meeting Your NeedsNarrow down the list of providers in your area by reviewing their health care specialty, education and experience.

ConvenienceYou may want to consider the location of the office and office hours when choosing a provider. The following questions may be helpful when choosing a physician.

Research and Ask QuestionsTo find the best fit for you, we encourage you to research providers by reading online reviews, checking if your health insurer offers quality ratings or asking friends and family for referrals. You can ask to see if the provider is available for a simple meet and greet to assess your comfort level with the individual.

Mercy Health Physician Partners offers more than 90 locations in West Michigan. You can search for a provider atMercyHealthPhysicianPartners.com

Your wellness visit is an important step in maintaining good health. Taking part in regular screenings, routine preventative care and scheduling visits for minor acute issues can help you get ahead of illnesses and health conditions and help reduce health care costs.

Find a physician at MercyHealthPhysicianPartners.com or 844-BeRemarkable

Make it easy to keep up to date with more stories like this.Download the 13 ON YOUR SIDE app now.

If you would like more information about advertising with 13 ON YOUR SIDE, please contact Jeff Olsen at jolsen@wzzm13.com.

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Tucsonans who have been moved, promoted or appointed in July-December 2019 – Arizona Daily Star

November 11th, 2019 11:46 am

Elizabeth R. Betsy Cantwell has been appointed as senior vice president for research and innovation for UA.

Cantwell will lead the UA Office of Research, Development and Innovation, which includes the Corporate Engagement Program, Tech Launch Arizona and the UA research parks.

She will be responsible for expanding the universitys capacity for knowledge creation and discovery; integrating efforts by faculty, students, staff and executive leaders to move inventions and technologies to the marketplace; increasing the UAs connectivity with external collaborators; spearheading industry and public partnerships; and increasing total research funding.

She joins the UA after serving as the CEO of Arizona State University Research Enterprise.

Cantwell moved to higher education after working for the Lawrence Livermore National Laboratory, where she was director for economic development and currently serves as a guest scientist.

Cantwell earned a masters in business administration from the Wharton School at the University of Pennsylvania after earning a doctorate from the University of California, Berkeley, in mechanical engineering and a bachelor of arts in human behavior from the University of Chicago.

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Laughter Therapy: 11-10-19 – West Hawaii Today

November 11th, 2019 11:46 am

Aloha all! Responding to several readers, I will start with some one-liners as a warm up. Then well get to some serious LOLs.

Why are math textbooks so stressed? They deal only with problems.

Why was the farmer upset? His cows were very moo-dy.

Why are movie stars so cool? They have so many fans. One more?

What happened when the wheel was invented? It caused a world-wide revolution! Duh!

The Texas sheriff was looking for a deputy. So, Chad, the new recruit who was a blonde man wanted the job.

OK, the sheriff drawled, Chad, what is 1+1?

Chad replied, 11.

The sheriff thought it was not what he expected for an answer, but it was correct. Then he asked, What two days of the week start with the letter T?

Chad answered, Today and tomorrow.

Again, the sheriff was surprised and thought that maybe Chad had a creative mind.

Now Chad, listen carefully, Who killed Abraham Lincoln?

Chad looked a bit surprised, thought for a few minutes, then responded: I dont know!

The sheriff said, Well, why dont you go home and work on that one for awhile.

So, Chad wandered over to the pool hall where his pals were waiting to hear about the results of his interview.

Hey Chad, How was it?

Chad responded, It went great. First day on the job and Im already working on a murder case! (Did you forget that Chad was blonde?)

Why did the snail get a giant letter S painted on his Ferrari? So people will say, Look at that S-car go!

A man and a dog walk into a talent agents office. The agent says, OK, lets make this quick. Im busy. Whats your talent?

The man says, Its not me sir, its my dog. He talks!

Yea right, says the agent. Get out! Im busy.

No wait, says the man, Ill prove it. He turns to the dog and asks, What do you normally find on the top of a house?

Roof! says the dog, wagging its tail. Then the man asks the dog, How does sandpaper feel?

Rough, exclaims the dog.

The agent again says, Youre wasting my time!

Just one more, pleads the dogs owner. He then asks the dog, Who was the greatest baseball player ever?

Ruth, barked the dog!

OK, thats it, and the agent forces them out the door. Turning to the man, the dog sighs and says, Maybe I should have said Joe DiMaggio?

A man tells his doctor that he cant do all the things around the house that he used to do. After a thorough exam and some blood test, the doctor says to the man, Well, in plain English, I think you are just lazy.

With a smile, the man says, OK, now give me the medical term so I can tell that wife of mine. Maybe shell even have some sympathy for me.

Yes, it is almost winter time. So remember, you know its a cold day when your teeth start chattering and theyre still on the night stand.

Now to close, looking at my medical career, I can honestly say that impeachment is like the emergency room. We need to practice preventative medicine. Last LOL, my friends, be well, do good deeds.

Aloha, a hui hou.

Shay Bintliff, MD, writes a monthly humor column for West Hawaii Today.

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Animal Planet’s ‘Crikey! It’s the Irwins’ features Oregon Coast Aquarium – The News Guard

November 11th, 2019 11:46 am

Animal Planets 'Crikey! Its the Irwins' will feature the Oregon Coast Aquarium in an upcoming episode on Saturday, November 23 at 5 p.m.

The non-profit Aquarium in Newport, invited the Irwin family to learn first-hand about the extensive animal care that the AZA-accredited facility provides.

The Animal Planet film crew documented Bindi Irwin assisting Aquarium husbandry staff in veterinary procedures and health checks for a wide variety of animals.

Boots, a harbor seal at the Oregon Coast Aquarium, is especially loved by visitors for her friendly demeanor. She found her home at the Aquarium after stranding on a beach in Mexico in 1988 as a pup.

At 31 years old, Boots is living much longer than she would in the wild. As a result, she needs increasingly specialized care to treat geriatric-related issues like arthritis. On the episode, Bindi works with Oregon Coast Aquarium Curator of Mammals, Brittany Blades, and Oregon Coast Aquarium Head Veterinarian, Dr. Dan Lewer, to provide a health check, laser therapy and chiropractic care to Boots.

It was great to meet and share information about animal care with Bindi, said Blades. She clearly has a good animal sense about her, and Boots responded very well to her, even interacting with her in the water after the exam.

"Bindi also mentioned that she had been considering using laser therapy at the Australia Zoo, so I think it was great for her to get this experience.

Laser therapy is just one example of the state-of-the-art medical care that the Aquarium provides for its animals. During her day at the Aquarium, Bindi also helps conduct an ultrasound on Dotty, the female dogshark, to check for pups and assists in annual health checks on a giant Pacific octopus and Japanese spider crab.

The Oregon Coast Aquarium is committed to providing the best quality care for its animals, which serve as ambassadors to the public for their wild counterparts. Restaurant quality seafood diets, highly trained staff, animal enrichment, and functional, natural habitats all contribute to this commitment, which is highlighted on the Crikey! episode. The Aquarium also partners with Willamette Veterinary Hospital to provide highly specialized veterinary care, including surgery, eastern medicine, preventative care and physical and laser therapy.

Terri Irwin, a Eugene, Oregon native, has visited the Oregon Coast Aquarium with her family for many years. The Irwins currently live in Australia where they own the Australia Zoo, a global zoological destination and world leader in wildlife conservation.

The entire Oregon Coast Aquarium team was ecstatic to host the Irwin family and Animal Planet and share our passion for wildlife. I think for many of us, it realized a lifelong dream, said Sally Compton, Oregon Coast Aquarium Communications and Marketing Manager. These relationships are essential because even from opposite sides of the world, we can work together to learn best practices for animal care. Ultimately, we share the same mission to educate people about wildlife and protect the planet.

If you are interested in watching the episode, tune into Animal Planet on Saturday, November 23 at 5 p.m. or catch it after it airs on http://www.animalplanet.com/tv-shows/crikey-its-the-irwins.

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New Hays business brings traditional office therapies to the door – Hays Post

November 11th, 2019 11:46 am

By JAMES BELLHays Post

Physical therapy is typically something a person does not think about until it is needed and then finding time during a workday when offices are open is often a challenge.

ButAimee Riegel opens to change that with her new business Fit PT and Physical Therapy.

What I have done is created a mobile concierge physical therapy practice where I can come to the client, Riegel said.

And she offers different services than what you might see in a traditional physical therapy office such as working with employers to develop programs for their employees to help them before therapy is needed.

A lot of them are simply because we sit too long during the day, she said. There is a lot of things I can teach people and employers to show their employees.

Working directly with the public can be beneficial for the individual as well in both well being and pricing, she said. Not being contracted with insurance companies means she can offer a flat rate sometimes lower than out-of-pocket costs after a traditional office setting.

You know what you get up front,Riegel said.

Working outside of insurance she said also allows her the flexibility to work with what the client needs regardless of the mandates of an insurance company.

We can make a plan and really follow through without having insurance dictating (care), Riegel said.

When the range of motion is recovered, insurance companies will often stop covering treatment thats where her new service can come in.

Working with people to maintain a range of motion can help stop problems from occurring that can happen when not seeking treatment.

She launched the business in September and has been gaining clients through word of mouth and continues working at Progressive Physical Therapy two days a week in order for clients who are going through insurance companies to be able to use her services as well.

But through the new business, she offers flexibility in scheduling that a regular office normal will not.

Im available evenings. I can be available weekends. I try to be as flexible as I can for my clients, Riegel said.

Ive gotten some really great responses from the community, she said, adding many have told her this service is much needed in Hays.

And while the service is new, many will already know Riegel as she has been a long-time practitioner of physical therapy.

I have been practicing physical therapy for about 12 years and decided I wanted to branch out into something a little different, she said.

Using her services can help maintain motion and stay pain-free, and utilizing physical therapy prior to a specific incident is becoming more popular.

The American Physical Therapy Association is actually pushing really hard for preventative wellness and medicine, Riegel said.

By doing so, they hope to keep insurance costs lower, she said, by engaging people before they have an issue.

Wellness services can also more personally directed than insurance-mandated treatment.

Its more than developing exercises for an individual. Its very personal, Riegel said.

She helps see how people move and can direct their treatment to address their specific concerns.

Riegel offers a free discovery consultation where she can hear problems and see if her services would be a good fit.

An initial full consultation is $150 for approximately an hour and a half and includes a full evaluation and treatment during the visit.

A regular session is $125 for wellness or physical therapy.

She also offers a half-hour session for $70 or stand-alone dry needling for $45.

Health Spending Accounts and Flexible Spending Accounts can be used and if multiple sessions are needed she offers discounted rates packages.

For more about the business or to set up a consultation, visit http://www.fitptandwellness.com, Facebook or call (785)261-1772.

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Gene Tech Company Claims to Have Found a Cure for HIV/AIDS – NewNowNext

November 11th, 2019 11:46 am

by Sam Manzella 11/8/2019

A group of medical researchers in Maryland believe the answer for curing HIV/AIDS may be gene therapy.

American Gene Technologies (AGT), a Rockville-based medical research company, has submitted a Investigational New Drug (IND) application with the FDA to begin gene therapy trials that researchers believe could eliminate HIV in people already living with the virus.

The drugan HIV treatment program called AGT103-Tis a single-dose, lentiviral vector-based gene therapy that AGT says could remove infected cells from the body and decrease or eliminate the need for lifelong antiretroviral treatment in HIV-positive patients.

If approved, the company hopes to begin a Phase 1 clinical trial that will examine the safety of AGT103-T in humans.

Getty Images

In a press statement, AGT chief science officer C. David Pauza, PhD, said the companys objective is to treat HIV disease with an innovative cell and gene therapy that reconstitutes immunity to HIV and will control virus growth in the absence of antiretroviral drugs.

AGTs approach differs from other medical researchers attempts to cure HIV. As NewNowNext reported earlier this year, researchers in Europe made headlines when two separate HIV-positive patients no longer had the virus after obtaining bone marrow transplants from donors with an HIV-resistant mutation to treat unrelated cancers.

Those patients marked the second and third time doctors were able to effectively cure patients living with HIV via bone marrow transplant in the history of modern medicine. However, HIV/AIDS activists and medical professionals were quick to raise concerns about the feasibility of curing HIV with bone marrow transplants on a more widespread basis.

Getty Images

Kenneth Freedberg, MD, a professor of medicine at Harvard Medical School and Massachusetts General Hospital, told NewNowNext in March that the method is not a remotely plausible strategy for HIV treatment for the vast majority of patients.

A bone marrow transplant is an extraordinarily toxic and life-threatening intervention, which you do if someone has an illness thats clearly going to be fatal, Freedberg explained. There must be no other treatment options available. It puts people at massive risk for infections and toxicity complications.

As the fight against HIV/AIDS wages on, communities at risk of contracting the virus continue to take preventative measures against new infectionsincluding daily use of Pre-exposure prophylaxis (PrEP), a potentially life-saving HIV prevention drug that is massively popular among gay, bisexual, and queer men.

In the United States, PrEP is pretty much exclusively available as Truvada, its brand-name version manufactured by Gilead Sciences with a very high retail markup. That may change soon, though: Earlier this week, the government filed a lawsuit against Gilead alleging patent infringement on PrEP, which was patented by public health researchers at the Department of Health and Human Services years ago.

Brooklyn-based writer and editor. Probably drinking iced coffee or getting tattooed.

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Living Longer Is All About Chemistry and the Miracle Molecules – Qrius

November 11th, 2019 11:46 am

Lizzy Ostler, University of Brighton

Given the opportunity to live much longer lives, many of us might feel less than thrilled at the prospect. After all, you might think, who would want to live an extra 20 years dealing with arthritis, dementia or heart problems?

But what if those years could be filled with youthful vigour or at least middle-aged comfort?

The ability to reverse, or slow down, the degenerative processes that come with increased age has been a long held human aspiration. Indeed it has provided a consistent focus for decades of scientific research on ageing.

But it is only in the last ten years that the replacement of palliative treatments (which suppress the symptoms of age-related diseases) with genuine anti-degenerative medicines (which prevent and repair) has become more than a pipe dream.

This paradigm shift stems from recent research that shows that just a few biological root causes underpin almost all the diseases of old age. Such a discovery is an opportunity to address a wide range of illnesses simultaneously with treatments that target single biological mechanisms. For the first time, ageing has become druggable.

One leading cause of age-related changes, including illness, is known as cell senescence. This is a consequence of evolution that only really comes into play when organisms outlive their normal reproductive age, or are subjected to a very damaging environment. When cells become senescent they can no longer divide, and typically behave in a way that damages the tissue around them.

For many years, much of the gerontological community had considered cell senescence to be a symptom rather than a cause of age-related decline. However, recent groundbreaking research showed that removing senescent cells from mice not only prevents normal ageing, but actually reverses many of the symptoms. This proof that senescent cells cause ageing finally provides us with the potential to develop a cure.

Follow up work has revealed that the positive effects of senescent cell removal in mice extend to myocardial infarction (which causes heart attacks), Alzheimers disease and metabolic dysfunction. The challenge now is to translate these findings to treatments in ageing humans.

To that end, major investors have now joined researchers in the search for ways to kill, remove or rejuvenate senescent cells. And they have made exciting progress.

For example, when combined, dasatanib (a leukaemia drug) and quercetin (a natural product found in vegetables), show improved health and lifespan in mice. And early results from clinical trials of this combination have demonstrated the first ever alleviation of physical dysfunction in patients with idiopathic pulmonary fibrosis, a progressive degenerative lung disease with no current effective treatment.

The list of common side effects associated with dasatanib means it would likely be restricted to only the most seriously ill patients. But the trials give hope for medicinal chemists to develop a more palatable second generation of similar drugs.

An alternative strategy is the rejuvenation of senescent cells. Resveratrol, found in red wine and chocolate, was shown to be able to rejuvenate senescent cells in the lab, restoring their molecular fingerprint and growth to that of normal youthful cells.

Importantly, this work also demonstrated that small synthetic modifications were able to tune the effects achieved - again demonstrating that a medicinal chemistry approach to the problem is highly likely to be successful.

Elsewhere, Fisetin, a natural product found in strawberries, apples and onions, was recently shown to confer both improvements in health and a reduction in the senescent cell load in old mice. It is now also the subject of clinical trials.

Interestingly, Fisetin also interacts with other key ageing mechanisms, such as nutrient sensing the biological mechanism that underlies the well known health and lifespan increasing effects of calorie restriction.

It is not yet clear whether this is a new kind of super-therapeutic that simultaneously targets more than one cause of ageing, or whether it will reveal a new piece of the jigsaw that allows us to integrate the known paths to morbidity into a coherent whole.

The research conducted so far, just using natural products and existing drugs, has shown unequivocally that small molecules can produce a broad spectrum of anti-degenerative effects.

Drug discovery for ageing is moving beyond its infancy, and preventative medicine that will revolutionise 21st-century healthcare is now genuinely possible. Now we need to add synthetic medicinal chemistry to the mix to develop safe and effective drugs that will help us all into a healthier and more active future.

Lizzy Ostler, Head of Chemistry, University of Brighton

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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13 Unexpected Reasons Why You Might Have A Fever – HuffPost

November 11th, 2019 11:46 am

Feeling a little heated? Its typically nothing to worry about especially if youre sick. However, other issues can cause your temperature to rise.

A normal body temp is typically around 98.6 degrees Fahrenheit (37 degrees Celsius) but can vary slightly for each individual, and even fluctuate depending on the time of day.

It can be lower in the morning and higher in the late afternoon and evening, said Michael Hall, a physician based in Miami. But when your temperature gets to 100.4 degrees Fahrenheit or higher, and lasts more than a few hours, youre getting into fever territory something that can be caused by a number of conditions.

Most of my patients understand that a fever is a common symptom of cold and flu, said Christopher Dietz, an area medical director at MedExpress Urgent Care. However, what some people might not realize is that a fever isnt always just a sign that youre coming down with something.

Heres what could also be at play, according to medical experts:

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Infections

If you are looking for the reason behind your elevated temperature, start here. Experts note that infections are commonly associated with a fever.

When the immune system detects a threat such as bacteria or virus, a substance known as pyrogens is released into the bloodstream to reach the hypothalamus, which regulates body temperature, said Diana Gall, a general practitioner with Doctor4U in the U.K. When the hypothalamus detects pyrogens, it raises body temperature and causes fever in an attempt to kill off bacteria and viruses.

She noted that a high fever is one of the ways your body is responding and fighting the infection but a body temperature that is too high can also be dangerous.

If the fever is persistent and isnt coming down with home remedies, you should see a doctor, particularly if the fever is accompanied by a severe headache, difficulty breathing, blood in your urine or stool, redness of the skin or rash, or vomiting, etc. The infection may be serious and your body temperature may not reduce without medical treatment, she said.

Overexerting yourself outdoors

Hot outdoor temperatures and internal heat generation from exercise and mechanical movement of the body can heat you up, said Phil Mitchell, national medical director at DispatchHealth.

Under normal circumstances, your body will function well enough to cool you down through sweating and dilation of blood vessels. But if these basic systems are overcome and you cannot cool down, your body will continue to increase in temperature.

This typically does not happen from exercise alone, but exertion in a hot environment can cause this under the right circumstances, Mitchell said. He noted that you should immediately remove yourself from the heat and try other methods to cool your body down if this is the case.

Heatstroke can occur if heat exhaustion is not treated promptly. You need immediate medical attention if you become confused, lose consciousness or if you have an elevated temperature in this situation, said Steven Reisman, a cardiologist and director of New York Cardiac Diagnostic Center.

Vaccinations

Vaccines to prevent a bacterial or viral infection prepare your body to come in contact with that infection later, said Erik A. Larsen, assistant director of EMS and emergency preparedness at White Plains Hospital in New Yorks Westchester County.

So when you get the vaccine, your bodys immune response is stimulated and the body says, Whoa, what is this? It then mounts a fever, he said.

Larsen added that when you get a vaccine, youre not really invaded by an active infection, but it tips your body off that sometime in the future you may come across this.

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Alcohol withdrawal

Low-grade fevers can occur during the first few days of alcohol withdrawal as the central nervous system, which has been suppressed by alcohol, readjusts, said Holly Phillips, a board-certified general internist in New York and a medical expert for RxSaver.

Alcohol withdrawal also causes tremors, which can affect your heat, Larsen said.

The body is reacting to the loss of not receiving alcohol, which creates muscle contractions. This makes the body shake like a tremor, and it raises the bodys temperature, he said.

Inflammatory conditions

Certain inflammatory conditions, like rheumatoid arthritis and lupus, can cause fevers, said Lisa Alex, a physician at Medical Offices of Manhattan. This also occurs because the body is producing pyrogens, which raises your temperature. So if you have underlying inflammatory conditions and have a flare-up of any sort, the result may be a fever.

Certain medications

Many medications like antibiotics [and] antimalarials can also cause drug-induced fever. Anticonvulsants and some herbal medications can also do the trick, said Soma Mandal, a New Jersey-based physician.

You should monitor your bodys reaction when taking any new medication.

Look for a fever that starts a week after starting a new medication and goes away once you stop taking the drug, said J. David Gatz, an assistant medical director of the emergency department at the University of Maryland Medical Center.

Blood clots

Blood clots are an under-discussed source of fevers, according to Nate Favini, medical lead at preventative primary care service Forward.

If youre experiencing fever along with pain, swelling and redness in your leg or shortness of breath, that could be a sign of a blood clot, he said.

Endometriosis

While rare, several of my patients have had fever and flu-like symptoms every month at the start of their periods, likely due to severe pelvic inflammation caused by chronic bleeding into the stomach from wide-spread endometriosis, said Kenneth Ward, director of Predictive Laboratories and a scientific advisor for Predictive Technology Group in Salt Lake City.

If you experience this, Ward suggested making an appointment with your physician to get screened for the condition. Additional symptoms can include debilitating cramps during your period or pain with sex, urination or bowel movements.

Recent surgery

If youve recently gone under the knife, especially for a chest or abdominal procedure, you may experience an elevation in temperature in the days to follow, known as postoperative fever.

The body produces inflammatory proteins in response to the trauma surgery ... This causes fever as a reaction for the first few days post-operatively, said Laurence Gerlis, CEO and lead clinician at SameDayDoctor in London.

Studies show that this is a common side effect from surgeries, with up to 90% of patients reporting elevated temperature after the fact. In most cases, this resolves on its own.

Fevers could also be a side effect to anesthesia, although thats more rare, said Erin Nance, an orthopedic surgeon and hand and upper extremity specialist in New York. This is called malignant hyperthermia.

When this happens, according to Nance, its because of your bodys response to common anesthetic agents used during surgery. This can present as a high fever, muscle rigidity and rapid heart rate. The condition can be fatal and is treated with a medication called Dantrolene and ice packs.

If you have a family history of malignant hyperthermia, it is critical to tell your anesthesiologist before proceeding with surgery, she said.

STIs

Rina Allawh, a board-certified dermatologist with Montgomery Dermatology LLC in Pennsylvania, said that certain sexually transmitted infections may cause a higher-than-normal temperature.

Initially, syphilis presents with a non-tender chancre (i.e. an ulcer). However, if left untreated, may result in high fevers, joint pain, lymph node enlargement and fatigue, he said.

Gonorrhea, if left untreated, may result in high fevers associated with a rash, Allawh said. To prevent life-threatening consequences, prompt recognition and treatment of the condition is essential, he said. Additionally, practicing safe sexual practices and sexual-transmitted disease testing is equally as important.

Traveling to another country

Depending on the area of travel, a rise in body temperature can often be attributed to tropical bacteria and protozoa not often seen in developed countries, said Amna Husain, a board certified pediatrician and founder of Pure Direct Pediatric in New Jersey.

For this reason, I recommend travelers consult with their physicians and refer to the (Centers for Disease Control) guidelines for safe food and water recommendations, she said.

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Hormone disorders or changes

Hyperthyroidism itself does not cause a fever, but we can see a very dangerous and fatal disorder associated with a large influx of thyroid hormone into the body called a thyroid storm, which does have fever, along with rapid heartbeat, fluctuations in blood pressure, and tremors associated with it, Husain said.

She noted that thyroid storm can occur because of a major stressor such as trauma, heart attack, delivery of a baby or because of an infection in people with uncontrolled hyperthyroidism.

In rare cases, it can be caused by treatment of hyperthyroidism with radioactive iodine therapy for Graves disease, she said.

Hormonal changes that occur during menopause can also cause you to feel warmer than normal, which are typically known as hot flashes.

Cancer

Keep in mind that a fever isnt necessarily the first sign or a major sign of cancer. However, it could be one of many symptoms.

Several cancers are associated with fever, which are most commonly leukemias and lymphomas, although other cancers can cause this as well, said Timothy S. Pardee, chief medical officer at Rafael Pharmaceuticals and an oncologist and director of Leukemia Translational Research at Wake Forest Baptist Health in North Carolina.

Pardee said this occurs because, in some cases, cancer cells create an inflammatory response, which then causes the body to respond with a fever. In other cases, the cancer cells themselves secrete cytokines or substances in the body that can cause a fever. And, according to Pardee, cancers like leukemia can impair your bodys ability to fight off infections resulting in prolonged illnesses and fevers.

Additional symptoms to look for are unintended weight loss and drenching night sweats (where you have to change your shirt or sheets when you wake up). These symptoms should prompt a call to your doctor for further evaluation, he added.

When you should be concerned about a fever

A fever may not be cause for alarm, unless there are some specific situations, said David Cutler, a family medicine physician at Providence Saint Johns Health Center in Santa Monica, California.

He added that medication to reduce fever when there is an infection like a cold, flu or pneumonia can help minimize bothersome symptoms like headache, body aches and dehydration from excessive sweating.

But if the fever is caused by hormonal effects, such as menopausal hot flashes or muscular activity like strenuous exercise, these medications will not be effective. In these instances, Cutler said to use measures like cooling fans to lower the bodys temperature.

According to Amesh A. Adalja, senior scholar at Johns Hopkins Center for Health Security in Maryland, a person should be concerned for fever above 101 degrees Fahrenheit (38.3 degrees Celsius) when it is unremitting, when it is associated with other symptoms such as dehydration, extreme fatigue, shortness of breath and severe rash.

Additionally, someone suffering who has a compromised immune system should have a low threshold for seeking medical attention. Same goes for those who are pregnant, have heart or lung disease, or who are very young, he said.

That said, if youre ever concerned about a fever, its always worth it to call your doctor. Thats what theyre there for, after all.

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13 Unexpected Reasons Why You Might Have A Fever - HuffPost

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UCT medical volunteer organisation to cut back activities after funding cuts – News24

November 11th, 2019 11:46 am

The Students' Health and Welfare Centres Organisation (Shawco) at the University of Cape Town (UCT) is set to cut back on some of its work after the institution reduced funding in October.

The university announced in a statement last week that Shawco would continue to provide its normal range of medical activities on the Cape Flats, but certain educational activities would be reduced.

Shawco has more than 3 000 student volunteers, but the number has dropped in recent years, placing the programme on a short list for UCT's tightening budget.

The organisation lost several members of its leadership after the cutbacks, leaving university officials and students unsure of its operating status.

"The current situation at Shawco requires an immediate response, and the executive leadership is committed to finding a viable solution that will ensure that its legacy is preserved," said UCT spokesperson Elijah Moholola.

Shawco has been operating for more than 75 years, providing free medical services to under-served communities in Cape Town. During apartheid, the organisation became well-known for providing medical services to protesters during conflicts with the police.

Today, Shawco runs 15 health and education projects across the Cape Metropole.

UCT medical students work at mobile clinics to provide services like screenings, testing for sexually transmitted infections, and preventative care.

The educational programmes are designed to better community understanding of health, wellness, and medicine, as well as reduce stigma toward diseases like HIV and tuberculosis.

These are the programmes that will be reduced over the summer holidays.

GroundUp contacted several members of Shawco's executive board for answers, including CEO Crain Soudien, to no avail.

Link:
UCT medical volunteer organisation to cut back activities after funding cuts - News24

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