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Maintaining good eye health is crucial for having unobstructed, clear vision, in the long run.

However, given the unhealthy environment surrounding us, fast-paced lifestyles, and bad eating habits we've developed, our eyes remain at a significant risk.

Rest assured, a healthy lifestyle and good diet can help you maintain strong eyesight.

Here are five natural ways to help improve your eyesight.

Certain vitamins, including Vitamin A, C, and E, and minerals like zinc and copper, are essential for good eyesight.

Carrots, broccoli, spinach, strawberries, and citrus fruits are great sources of all these vitamins and minerals, and green/yellow vegetables, in general, are beneficial for your eyes.

Furthermore, foods rich in omega-3 fatty acids such as salmon, nuts etc. can also help.

Performing eye exercises regularly can go a long way in giving you good eyesight.

Rubbing, warming, gentle eye massages are a few such exercises.

Additionally, staying physically fit is important, especially if you're overweight or obese, since obesity increases the risk of developing Type-2 diabetes which, in turn, can damage the tiny blood vessels in your eyes, thus affecting eyesight.

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Enough quality rest is instrumental in maintaining good eyesight.

Sleep helps your eyes to repair and recover from the stress of the day and continued exposure to computer screens.

One should aim for sound, undisturbed, 7-9 hours of sleep each night to improve eyesight.

Frequent mini-breaks and power-naps during the workday also go a long way in providing some much-needed rest to your eyes.

When working in environments harmful for your eyes, like a laboratory or a garage, wearing appropriate protective eye-gear is a must.

Additionally, when heading out during the day, consider wearing good quality sunglasses. This will help protect your eyes from the harmful UVA and UVB radiation from sunlight.

Also, go for regular eye checkups and see if there's a need for spectacles or not.

Unhealthy lifestyle habits are also known to adversely affect eye health.

Smoking, among other harms, significantly raises your risk of developing cataract and age-related macular-degeneration.

Fortunately, however, your eyes, lungs, and other body parts start recovering from tobacco-induced damages fairly soon after you quit smoking.

So quit now, if you want yourself (and your eyes) to live a healthy and long life.

More:
Five simple ways to improve your eyesight - NewsBytes

Eye check-ups essential to avoid long-term damage. (Source: Getty Images/Thinkstock)

A public campaign that seeks to promote eye health care among people in Uttar Pradesh and is supported by legendary actor Amitabh Bachchan, is all set to be intensified after its eight-week pilot project in five districts of the state bore good results, an Australia-based foundation said.

See Now campaign was launched in June with pilot in Lucknow, Lakhimpur Kheri, Rae Bareilly, Unnao and Sitapur districts. We are truly honoured that megastar Amitabh Bachchan agreed to become the face of this important campaign. And, we aggressively use social media tools like Facebook, Twitter and WhatsApp to reach out to as many people as possible, besides printed literature. And, Bachchans face on that has made a difference, a senior official of Fred Hollows Foundation said.

ALSO READ | Vision problems affect 2.2 billion people, warns WHO

The Australia-based foundation was started in 1993 by doctor Fred Hollows and currently operates in 27 countries, including Ethiopia, Kenya, Rwanda, Vietnam, Malaysia, Suriname and Indonesia, said Nick Martin, director of public affairs at the foundation.

During the pilot period, through pamphlets bearing messages delivered by Amitabh Bachchan or the video featuring him, we have been able to reach out to people, both patients and their families, with the primary focus of urging them to get the eyesight checked, he said.

And, now we are going to intensify this campaign possibly by December this year and going to give to a more formal shape. The results of that should start coming by next February, he added.

The See Now campaign is funded by The Fred Hollows Foundation and in part by Essilor Vision Foundation, and in partnership with Sightsavers India and Vision2020 India, among others.

The India Vision Institute (IVI), a not-for-profit trust that works in the field of eye care, has also decided to join hands with the foundation to strengthen the campaign, CEO of IVI Vinod Daniel said.

Martin and Daniel, both Australia-based, recently also met senior officials of the Uttar Pradesh government in Lucknow to seek support.The campaign, besides raising awareness on eye care also aims to put together all stakeholders and connect them so that people can raise their knowledge or get eyesight checked or seek treatment at the earliest, Martin said.

ALSO READ | World Sight Day 2019: Simple home remedies to keep your eyes healthy

He said during the pilot phase, the team found out that many people were not going for eye testing because they thought it was a curse.Vision problems are extremely common in India. Currently about 550 million Indians have serious vision problems which affect their families, their work and their quality of life, Bachchan had said in his campaign message after the launch.

It really is so simple to avoid a lot of different sorts of blindness, he had said.

Amitabh Bachchan hails from Uttar Pradesh and wears glasses, so he telling people to go get eyesight checked really gets heard, Martin said.

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See Now campaign will be soon intensified: Fred Hollows Foundation - The Indian Express

Cataract is the principal cause of blindness for people above 50 years in India, according to the National Blindness and Visual Impairment Survey of India (2015-19), adding that barriers to accessing treatment include the following no one to accompany [the patient], seasonal preferences, and financial constraints.

Among men, the most important barriers are financial constraints (31%) and local reasons (21.5%).

Among women, local reasons (23.1%) and financial constraints (21.2%) were the most important barriers.

Cataract is the cause for 66.2% cases of blindness, 80.7% cases of severe visual impairment, and 70.2% cases of moderate visual impairment in the age group.

Also, blindness is more pronounced among illiterate (3.23%) than literates (0.43%) and more prevalent in the rural population (2.14%) than urban (1.80%).

What makes this worse for India is the fact that approximately 93% of cases of blindness and 96.2% visual impairment cases in this age group were avoidable.

Of all the avoidable causes, more than half were treatable, found the survey.

The survey was conducted by Dr. Rajendra Prasad Centre for Opthalmic Sciences, All India Institute of Medical Sciences, New Delhi, for Union Ministry of Health and Family Welfare.

The survey was conducted in 31 districts of 24 States in the country.

Financial constraint was found to be the biggest barrier in accessing a cataract surgery with this being a reason for 22.1% blindness cases and lack of awareness was behind 18.4% cases, who did not feel any need of the surgery, the survey noted.

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Cataract major cause of blindness above 50 - The Hindu

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.)

Michele McDonnall, Mississippi State University and Jennifer L. Cmar, Mississippi State University

(THE CONVERSATION) Communities across the world observe White Cane Day on Oct. 15 to recognize the contributions of people with blindness and low vision and to promote equal opportunities. The day was first observed in the U.S. in 1964, when Congress passed a law to increase awareness about the white canes role in promoting independent, safe travel for people with blindness or low vision.

More than 7.5 million Americans, or 2.4% of the population, are blind or have low vision. Some people are born with blindness or low vision, but most people acquire vision loss, often at older ages. Researchers estimate that the incidence of blindness and low vision will rise rapidly through 2050 as the population ages.

As researchers who study issues related to blindness and low vision, we are interested in how society, its institutions, businesses and individuals currently perceive members of this population and how these perceptions may influence opportunities, particularly in terms of employment.

How the world has changed

Since passage of that law 55 years ago, the world we live in has changed drastically. Advances in technology have significantly changed our everyday lives, and much progress in accessibility and inclusivity has occurred. Federal laws that protect people with disabilities from employment discrimination have been passed, and many companies have since adopted inclusive hiring practices.

Assistive technology such as screen readers and screen magnifiers improve access to information and jobs. Built-in accessibility features in mainstream technologies are increasingly common. Accessible transportation options are continually evolving, including ride-hailing services and autonomous vehicles.

These changes and innovations have increased opportunities and reduced some barriers for people who are blind or those who have low vision (for simplicity, we will use the term blind going forward).

Ongoing employment challenges

One thing that has not changed for many people who are blind is lack of access to the workforce. This is true for people with all types of disabilities, hence the celebration of National Disability Employment Awareness Month in October. Our team of researchers at the National Research and Training Center on Blindness and Low Vision is addressing this issue for people who are blind.

The large disparities in employment rates that have historically existed for people who are blind still exist today. The most recent data from the American Community Survey indicates that 44.2% of people who are blind are employed and 10% are unemployed. This compares to an employment rate of 77.2% and unemployment rate of 4.8% for people without disabilities.

Why does employment continue to be a challenge for so many people who are blind? It may be that perceptions about the capabilities of the population have not changed.

Employer perceptions about blind people

One of the most common barriers to employment for people who are blind is negative employer attitudes. In several studies conducted between 2012 and 2017 with almost 1,000 employers, we measured employer attitudes and knowledge about how blind people can perform basic job functions. We included a measure of explicit (self-reported) attitudes toward individuals who are blind as employees and a measure of implicit attitudes about the competence of people who are blind. Implicit attitudes refer to subconscious beliefs or stereotypes that a person may hold but not be aware of and thus would be unable to report.

Our research with employers revealed the following:

-

Employer knowledge is limited about how people who are blind can perform basic job tasks.

-

Self-reported attitudes vary widely among employers, from extremely negative to completely positive, but on average they fall in the middle, or neutral, range of our attitude measure.

-

Implicit attitudes also vary, but on average are strongly negative, indicating that employers tend to automatically associate competence with sighted people and incompetence with blind people.

-

Knowing how blind people can perform job tasks is related to more positive self-reported and implicit attitudes.

-

More positive self-reported employer attitudes are associated with a greater likelihood of hiring someone who is blind.

Our results verify the importance of employer attitudes toward blind people because of the association between attitudes and hiring. We know that knowledge is associated with more positive employer attitudes, but that knowledge is lacking among employers, and presumably among society in general. One potential avenue to improve employer attitudes is through increasing knowledge about how people who are blind function on the job. Most employers likely assume that a blind person cannot perform many essential job functions when in reality this is incorrect.

People who are blind can perform most jobs that sighted people can. There are not jobs for blind people, rather, most occupations in the economy are available to this population, given appropriate accommodations. You might be surprised to learn that people who are blind work in a variety of jobs.

They are architects, artists, auto mechanics, fashion designers, engineers, scientists, physicians and judges. Many jobs previously unavailable to people who are blind are now accessible thanks to advances in technology.

What people can do to open up opportunities

Many employers have inaccessible job application sites, and people who are blind have filed lawsuits regarding their inability to use a screen reader to access job-related information on websites. Giving this group of people equal access to learn about and apply for any job of interest is an important first step. Employers should make all digital information related to jobs accessible, including the application process. Accessibility is not difficult, and much support is available for this effort.

In addition, employers and society in general should learn about how people who are blind can perform tasks for which sighted people rely on their vision. This is one of the best ways to change perceptions. Attending your local White Cane Day event is a great opportunity to learn about this population. Events such as this and National Disability Employment Awareness Month are important to increase awareness about the capabilities of people who are blind and the employment challenges they continue to face.

[ Youre smart and curious about the world. So are The Conversations authors and editors. You can read us daily by subscribing to our newsletter. ]

This article is republished from The Conversation under a Creative Commons license. Read the original article here: http://theconversation.com/blind-people-have-increased-opportunities-but-employers-perceptions-are-still-a-barrier-124977.

Originally posted here:
Blind people have increased opportunities, but employers perceptions are still a barrier - The Edwardsville Intelligencer

The sun was shining with a chill in the air as beep baseball teams from all over Texas gathered Saturday at Moore MST Magnet School in Tyler for the 11th annual Great Texas Shoot Out, an event intended to raise awareness for breast cancer and blindness.

Beep baseball is a form of baseball for those who are blind or visually impaired. There are six fielders and two bases that are randomly triggered by an operator. When the batter hits the ball, they must run to the base that is beeping before a fielder picks up the ball. If they get to the base first, the batting team gets a run. Just like traditional baseball, each team gets three outs per inning, but each batter gets four strikes per at-bat in beep baseball.

The Tyler Tigers, in conjunction with the National Beep Baseball Association, hosted the tournament to raise funds for the Susan G. Komen foundation and help pay for their trip to the Beep Baseball World Series in Ames, Iowa, happening in July 2020.

Texas teams from Austin, Bryan-College Station, Dallas/Fort Worth and Houston came out to participate and support the cause in recognition of breast cancer and Blind Awareness Day.

During opening ceremonies, Tracy Sawyer was named the 2019 Breast Cancer Queen, John Ingram was crowned the 2019 Shoot Out King and Tatyana Contreras, 12, was deemed the 2019 KOOL (Kids of the League) Kid.

Members of the Tyler Lions Club also presented the Tyler Tigers with a $1,000 check donation.

Tyler Lions Club Member Rip Duncan threw out the ceremonial first pitch, Contreras hit the ceremonial first ball and the games began.

Once in the swing of things, players from every team showed support for one another during each play and fun was had by all.

Originally posted here:
Tyler Tigers raise awareness of breast cancer and blindness with beep baseball tournament - Tyler Morning Telegraph

New Delhi: The estimated prevalence of blindness in India has reduced by approximately 47% in last 12 years, while untreated cataract continue to be leading cause of blindness, a government survey has revealed.

According to the National Blindness and Visually Impaired Survey (2019) released by Union Health Minister Harsh Vardhan on Thursday, the estimated blindness has came down to 0.36% from 1% in 2006-2007since the last survey. According to the survey report,the visual impairment has come down by 51.9% to 2.55% as a compared to 2010.

As per the survey report, the maximum prevalence of blindness was seen in age group of above 80 (11.6%), followed by 70-79 age group (4.1%), 60-69 age group (1.6%) and 50-59 age group (0.5%). The survey noted that the most of the blindness (92.9%) and visual impairment (96.2%)cases were due to avoidable causes.

The current survey was conducted between 2015 and 2018 by Dr Rajendra Prasad Centre for Ophthalmic Sciences of the All India Institute of Medical Sciences (AIIMS), New Delhi in association with ministry of health and family welfare. The survey covered over 93,000 people aged equal and above 50 years using Rapid Assessment of Avoidable Blindness (RAAB) method in 31 districts of 24 states and Union Territories.

People suffering from blindness have reduced from 12 million in 2006-07 to 4.8 million in 2019. This indicates that the country is close to achieving the World Health Organizations (WHO) goal of reducing it to 0.3% of the total population by 2020," said Harsh Vardhan.

This is 47% decline and the findings of the current survey are for blindness as defined to be vision of less than 3/60 in the better eye.The WHO had set the goal of lowering the prevalence of visual impairment by 25% by 2019 as compared to 2010 levels," he said.

India changed its over four-decade-old definition of blindness in 2017, bringing it in line with the WHO criteria. According to the new definition, a person who is unable to count fingers from a distance of three metres would be considered "blind" as against the earlier stipulation of six metres, which was adopted in 1976.

The survey also revealed that in 66.2% cases the cause of blindness was untreated cataract. The survey found a higher prevalence of blindness in illiterates i.e. 3.23% in comparison to 0.43% among 10 pass and above. Further the report noting a rural urban divide, said that blindness was more prevalent in rural population i.e. 2.14% as compared to 1.80% in rural population.

Blindness was found to be lowest in Thrissur district in Kerala and in Thoubal district in Manipur whereas Bijnor distirct in Uttar Pradesh witnessed the highest prevalence. The house-to-house survey was designed to generate representative data for the sampled districts as well as for India. An additional survey was conducted between 0-49 years age group in Jan-Feb 2019 and covered 18,000 people in six districts across various regions of India," Promila Gupta, Principal Consultant, National Programme for Control of Blindness, Ministry of Health said.

"The results of both surveys, in 0-49 age group and in equal and above 50 years population, were used to estimate the prevalence of blindness and visual impairment in India across all age group," she said.

Link:
Estimates of blindness reduced by 47% in 12 years: Govt survey - Livemint

Sleep apnea linked to blindness in diabetic patients

New York, Oct 15 (IANS) Severe sleep apnea is a risk factor for developing diabetic macular edema, a complication of diabetes that can cause vision loss or blindness, a study said.

For the study, the research team looked at the data from all patients diagnosed over an 8-year period at Chang Gung Memorial Hospital in Taiwan.

"Based on the results, we hope that more medical professionals will approach sleep apnea as a risk factor for diabetic macular edema," said study researcher Juifan Chiang from Taiwan.

This condition is called ''Diabetic Retinopathy'' and is a leading cause of blindness in the US.

Diabetic macular edema is more difficult to treat in patients with severe sleep apnea, the researchers said.

When diabetics have poor control over the blood sugar levels, tiny blood vessels at the back of the eye can become damaged.

Sometimes, tiny bulges protrude from the blood vessels, leaking fluid and blood into the retina. This fluid can cause swelling or edema in an area of the retina that allows us to see clearly.

According to the researchers, sleep apnea may contribute to the development and worsening of Diabetic Retinopathy by increasing insulin resistance, elevating inflammation and raising blood pressure, all of which can damage the blood vessels at the back of the eye.

They found the rate of severe sleep apnea was significantly higher in patients with diabetic macular edema compared with those without diabetic macular edema (80.6 per cent vs. 45.5 per cent).

They also found that the worse their sleep apnea was, the worse their macular edema.

Severe sleep apnea was also more prevalent in patients who needed more treatment to control their macular edema.

The study was presented at the 123rd Annual Meeting of the American Academy of Ophthalmology in the US.

--IANS

bu/ar/kr

Disclaimer :- This story has not been edited by Outlook staff and is auto-generated from news agency feeds. Source: IANS

The rest is here:
Sleep apnea linked to blindness in diabetic patients - Outlook India

In an effort to prevent post-operative vision loss, Dr. David Anschel is on a mission to convince hospitals to adopt his invention.

Its not common for patients to lose their vision after surgery. But when it happens, its devastating. Of the 2 million spine, brain and cardiac surgeries performed each year, 3,500 result in whats known as post-operative vision loss, or POVL.

Thats according to research by Dr. David Anschel, who is board-certified in neurology, clinical neurophysiology and epilepsy and currently heads up the Comprehensive Epilepsy Center of Long Island at St. Charles Hospital in Port Jefferson. Through his company, Rocky Point-based Anschel Technology, he has invented SightSaver, an FDA-approved and patented device that monitors the visual system during surgery and helps reduce the risk of POVL. To hospitals across the country, Anschel is pitching SightSaver as an upgrade to the system they might already have in place, claiming his device is more comfortable, more hygienic and more reliable. And, he said, the device has already been used on hundreds of patients across the country. Anschel spoke with LIBN about the process and what compelled him to become an inventor.

Is there a direct connection between your medical specializations and your invention?

I have a sub-specialization in clinical neurophysiology including intraoperative neurophysiological monitoring. I was serving on the faculty of Stony Brook University Hospital as its director of intraoperative monitoring when I made the decision to develop a better solution for monitoring the visual system during surgery. This involves monitoring and preserving the integrity of the nervous system during surgery. In 2006, my patient went blind during spine surgery and I wanted to find a way to prevent this horrible complication.

That must have been terrible. What is the process of developing such an invention?

After my patient went blind, I tried using the various products on the market at that time for monitoring vision function during surgery, but they did not provide good results. I then began making modifications to some of the off-the-shelf products, which ultimately led to my inventing a new solution the SightSaver, to prevent blindness, which is nearly the worst possible surgical complication, second only to death.

Is there a specific problem that SightSaver addresses?

Post-operative visual loss, or POVL. Many people have no idea that the risk of vision loss during surgery exists. This is particularly true for the over 2 million higher risk operations performed in the U.S. each year. It is not fully understood why some patients become blind during non-intracranial surgeries, but we do know that most are due to optic nerve ischemia [damage of the optic nerve that caused by a blockage of its blood supply, according to Merck Manuals]. The SightSaver helps prevent potential vision loss through better detection and intervention using visual evoked potentials, which is a highly sensitive method for detecting optic nerve dysfunction such as ischemia.

Do certain surgeries pose a higher risk of potential vision loss?

Certain brain and ocular procedures are the highest risk. Additionally, cardiac and spine surgery each are associated with much higher rates of POVL than other non-ocular procedures. However, POVL can occur in a wide range of surgeries, from joint replacements and peripheral vascular to rhinoplasty and certain urological and gynecological procedures using robotics.

What do you tell hospitals as to why they should choose your device over what they are currently using in their surgical units?

SightSaver may help prevent the second worst possible surgical complication. The risks posed by SightSaver appear to be negligible, with a minimal additional cost, which should be recovered likely at a profit by the hospital. These would seem compelling enough reasons for hospitals to explore a better way to monitor the visual system during surgery. For the hospitals across the nation who have already been using the SightSaver on hundreds of patients, I think its value proposition has been demonstrated.

You mention profits, but would your device play a role in helping contain healthcare costs?

The costs of blindness are tremendous. Each case of prevented blindness represents an enormous savings to our healthcare system and allows that person to remain a more productive member of society.

Tell us about what its like to pitch your device in regions where there is a broad selection of high quality hospitals and other healthcare providers?

Competition encourages innovation and implementation of new treatments, so it is very important. Unfortunately, the trend in this country is towards a more centralized and less innovative environment. Thats why in presenting the SightSaver my first outreach within a hospital is to its surgeons, neurologists and anesthesiologists, because their primary focus is on their patients and not on maintaining the status quo.

Did you always want to be a doctor or do you believe there was always an inventor inside you that possibly could have taken you down another career path?

I have always been a curious person and interested in science. Over time, I eventually focused on medicine, but could see myself shifting paths at some point. Where that path may lead, I dont know yet.

What advice do you have for other inventors as they seek to secure FDA approval?

Be persistent and try to lead each step of the process, but dont be afraid to seek help. I did work with a design engineer on the product design and an electrical engineer on the circuitry. Once the device was produced, I subjected it to clinical trials leading to research abstracts attesting to its performance efficacy [and] presented at scientific conferences and ultimately peer-reviewed publications.

Read the original post:
Executive Profile: Dr. David Anschel - Long Island Business News

President of the St. Kitts Society for the Blind, Mr Rockliffe Bowen, has on behalf of the executive and members of the society thanked the St. Kitts (Basseterre) Lions Club for remembering and positively engaging persons with disabilities at a beach picnic celebration Saturday at the Anchorage in Frigate Bay.

I want to say on behalf of our executive how appreciative we are in the Lions Club remembering us, because too many times we feel left out and we feel that nobody is studying us, he said. But I must say that the Lions Club they have come forward and they have put on this wonderful beach picnic for us and we must give our sincere thanks to them.

I must say thanks on behalf of both organisations, to the St. Kitts Basseterre Lions Club for the invitation they have extended to us by providing this wonderful food and everything that we are partaking of, Bowen, who is also the Vice President of the McKnight Community Centre-based St. Kitts and Nevis Association for Persons with Disabilities, added.

October is observed as the Blindness Awareness Month and Lions Clubs worldwide celebrate the blind in the month according to the President of the St. Kitts (Basseterre) Lions Club, Ms. Charmaine Pemberton. World Sight Day was observed on Thursday and this years call to action was Vision First!

Today we are here with the members from the St. Kitts Society for the Blind having a picnic out for them, said Ms Pemberton. Every year we do this picnic, bring out the blind to socialise with us, and have some fun, play dominos, cards we do games, we do swimming. This morning went on a walk from the Cenotaph and we are now here at the beach having fun.

The walk, themed Journey for Sight, started at 6 a.m. from the Cenotaph at the War Memorial in Fortlands, down on the Bay Road, on to Sandown Road, left to Pond Road, straight up Cayon Street via Greenlands, left to Burden Street, and back to the Cenotaph. In the afternoon they assembled under a large tent on the beach at the Anchorage in Frigate Bay where they had a sumptuous meal, played dominos and others swam in the sea.

The St. Kitts (Basseterre) Lions Club will also make a presentation Tuesday to the St. Kitts Society for the Blind and the St. Kitts and Nevis Association for Persons with Disabilities at the McKnight Community Centre. According to Ms Pemberton the presentation will include dominos and cards in braille for their enjoyment, and braille books for their reading.

Members of the McKnight Community Centre-based St. Kitts and Nevis Association for Persons with Disabilities are sponsored by the government of St. Kitts and Nevis agency, Skills Training Empowerment Programme (STEP).

Also I want to say thanks to the persons who showed up here this afternoon to participate in this social event, members of both organisations, the St. Kitts Society for the Blind and the St. Kitts and Nevis Association for Persons with Disabilities which is located at the McKnight Community Centre, Bowen said.

Others present and who helped out included St. Kitts (Basseterre) Lions Clubs 2ndVice President Ms. Heather Grant; Secretary Ms. Toshie Davis; Past President Ms. Adora Warner; and members of the club.

View post:
Lions Club honours visually impaired in celebration of Blindness Awareness Month - The St. Kitts-Nevis Observer

Benjamin Yerxa, chief executive of the Foundation Fighting Blindness, said results from a recent clinical trial represented a major step forward for sufferers of a degenerative disease called retinitis pigmentosa

A leading non-profit group funding research into treatments for retinal degenerative diseases has hailed as major step forward a potential therapy developed by ().

The comments from Benjamin Yerxa, chief executive of the Foundation Fighting Blindness, followed the presentation of data from a phase I/IIa clinical study by trial investigator Pravin Dugel.

He has been working on ReNeurons human retinal progenitor (hRPC) stem cell line, which has shown early promiseimproving, or stabilising clarity of vision in people with the degenerative disease retinitis pigmentosa.

Dugel's address to the American Academy of Ophthalmology Annual Meeting in San Francisco was based on the latest results from the clinical assessment of the drug candidate, published on October 2.

After the presentation, Yerxa said: "We're excited by the progress of ReNeuron's hRPC therapy.

From the Foundation's perspective, any gain in vision, or even stabilisation, is a major step forward for patients with RP as currently it is a condition where progressive loss of vision leads to blindness."

Earlier this month ReNeuron said it had seen rapid and profound results in the first three patients of the second phase of clinical studies of its human retinal progenitor cells.

The phase IIa trials saw noticeable improvements in visual acuity as measured by the number of letters that could be read on a standard eye chart.

Six months after treatment there was a mean improvement of 18.5 letters per treated eye, with a mean improvement of 12 letters per treated eye after nine months, whereas inexorable disease progression is the norm for this disease.

With total of 22 patients now treated and the study still ongoing, ReNeuron said the efficacy in subsequent patients was seen but at a lower rate and magnitude, with improvement in visual acuity ranging from +5 to +11 letters in the treated eye three months after treatment.

I believe that we are seeing a clear signal of efficacy in this patient population where any gain in vision, let alone the levels seen in some of these patients, is so hard to come by and so very much appreciated," said Dr Pravin Dugel, managing partner at Retinal Consultants of Arizona and clinical professor at the Roski Eye Institute in Los Angeles.

Read the original post:
ReNeuron cell-based treatment hailed by leading non-profit group funding research into treatments for retinal degenerative diseases - Proactive...

Sarah Ferguson is telling all on how shes fighting the signs of aging.

Ive had a lot of help to look like this at 60! the ex-wife of Prince Andrew told UKs Daily Mail newspaper on Thursday. Ferguson, nicknamedFergie, revealed shes a fan of non-invasive laser facelifts to keep her features youthful.

Ive started the laser treatment, but its not finished yet, said the proud mom of Princess Eugenie and Princess Beatrice. The collagen needs to rebuild. I hope it will all be done by my birthday.

PRINCESS MADELEINE, PRINCE CARL PHILIP OF SWEDENS CHILDREN LOSE THEIR ROYAL TITLES

The Duchess of York said she used the same treatmentlast year to prepare forPrincess Eugenies royal wedding. People magazine reported the laser lift is meant to work as a natural facelift, stimulating collagen and refinishing skin texture.

Sarah Ferguson, Duchess of York, and Princess Beatrice of York arrive for the royal wedding of Princess Eugenie and Jack Brooksbank at St George's Chapel in Windsor Castle, Windsor, Britain October 12, 2018. (Reuters)

I dont like the frozen look, said Ferguson, who turns the big 6-0 on Oct. 15. Im so animated and I like to be myself. I dont like the thoughts of needles and am very glad if I look well and happy Im really happy to be open about what Ive had done.

ELIZABETH HURLEY MET MEGHAN MARKLE BEFORE PRINCE HARRY DID: 'SHE WAS FANTASTIC'

Ferguson admitted that in the past, she has tried Botox. But these days, Ferguson insisted she relies on more minimally invasive treatments. Shes a fan of mesotherapy, which uses injections of vitamins, minerals and amino acids to boost collagen production. Ferguson said the treatment was the right choice for her after years of sun damage.

I need to repair the damage that was done on the beach when I was a child, she said. Its why I had the mesotherapy, the vitamin cocktail to hydrate and boost the skin.

After that therapy session in 2013, Ferguson said she had a facial thread lift, which involves inserting amesh of medically advanced threads under the skin, lifting the face and smoothing away fine lines.

KATE MIDDLETON'S BROTHER JAMES ANNOUNCES ENGAGEMENT TO FRENCH GIRLFRIEND ALIZEE THEVENET

Sarah Ferguson arrives for the wedding ceremony of Prince Harry and Meghan Markle at St. George's Chapel in Windsor Castle in Windsor, near London, England, Saturday, May 19, 2018. (AP)

ELTON JOHN WRITES QUEEN ELIZABETH SLAPPED HER NEPHEW ACROSS THE FACE IN FRONT OF HIM IN NEW BOOK

Its like garden trellising for sweat peas, said Ferguson. You insert the threads under the skin with a fine needle and they hold everything up. They also encourage collagen production. It takes a couple of months, then the sweat peas blood.

Before I had it done I thought, Oh, this is going to be so painful, but it wasnt bad, Ferguson continued. My skin responded well. I think if you look at photos of me after I had it done, I look much better.

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And her face wasnt the only thing Ferguson focused on.

According to the outlet, Ferguson traveled to the Bahamas earlier this year to have regenerative stem cell therapy on her feet.

PRINCESS BEATRICE ENGAGED TO EDOARDO MAPELLI MOZZI

Sarah Ferguson is getting candid about how she's fighting the signs of aging. (Reuters)

PRINCESS CHARLOTTE 'LOVES' UNICORNS, DAD PRINCE WILLIAM SAYS

I think my toes were ruined by all the riding I did when I was young, she explained, pointing to her big toe. They shaved the bone here and implanted stem cells, 20 million of them taken from my midriff, into my feet to make new cartilage. It takes about six months to heal but now I can walk in heels!

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Sarah Ferguson gets candid on using Botox, laser facelifts and stem cell therapy for her feet - Fox News

Posted: Oct 8, 2019 / 09:45 AM GMT-0600 / Updated: Oct 10, 2019 / 01:15 PM GMT-0600

Stem cell therapy is one of the most successful procedures ever for solving joint pain. Your own bodys cells are injected back into the area where healing is needed: back, neck, hip, shoulder, etc. The new cells signal to body the need for regeneration, which starts to take place.

The treatment is a one-and-done injection, no surgery. Regenerative Medicine of Utah successfully treats many with stem cell therapy. One patient, John Dunn, was scheduled for knee replacement because of bone on bone pain. Before surgery he received an injection. Three months later and regenerated tissue was found in his knee joint. Six months later his knee was even better than that.

In just four weeks John was out of pain, but the body wasnt done healing. The cells continue signaling to the body the need for healing. Its usual to allow 12 months for the regeneration process to complete and reach its limit.

Making sure youre a candidateis important. Not everyone needs it. Many patients that end up being a candidateinitially thought they werent eligible. To know if youre a candidate schedulea consultation.

Right now, at Regenerative Medicine ofUtah an evaluation is $49 for the first 25 callers to (800)453-0286.

This article contains sponsored content.

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How the bodys cells can prevent the need for surgery - ABC 4

For the last few years, writers and scientists have marveled at the potential for gene editing to allow farmers to grow more food on less land and allow more of the earth to grow carbon-sucking forests and savannas.

The main advantage of gene editing is precision. Its right there in the name: Instead of dealing with the randomness of breeding, or the rough power-tool work implied by the term genetic engineering, the editing suggests that scientists could now change the letters of genetic code with the same ease that a writer corrects typos.

But in late July, FDA scientists found a chunk of bacterial DNA in gene-edited calves, prompting people to wonder if this precision tool wasnt as precise as advertised. That hopeful vision of a gene-edited future verdant with pesticide-free, carbon-sequestering crops flickered.

On Monday, the scientists studying these gene-edited cattle published a paper in the journal Nature Biotechnology explaining what happened. Essentially, this new paper tells us that gene editing precisely tweaked specific letters of DNA, exactly what it was supposed to do. But scientists also used older, cruder tools, and one of those caused the genetic typo. Even so, the end result might be that gene-editing slides into the muck of controversy over GMOs.

To be clear, the cows at the center of this study have nothing to do with creating more productive, pest-resistant foods. The scientists had edited their genes in stem cells, which grew into calves without horns. Farmers usually remove the horns to prevent cattle from injuring each other goring is a real danger.

When I visited the University of California Davis in 2015, I saw a pair of these black-and-white bull calves standing and chewing in an outdoor pen, like ordinary but adorable bovines. Unlike other calves, however, they wouldnt have to suffer through a painful dehorning operation, in which a veterinarian burns out their horn buds.

Some cows are naturally hornless: Angus and Hereford breeds, for instance. But those are beef cattle. For dairy you want Holsteins or Jerseys, and these champion milk producers are more carefully bred than the winners of the Westminster dog show. If you started crossing muscled Herefords with black-and-white Holsteins, it would take decades of breeding to move the hornless trait into the dairy line then weed out all the beefy traits.

What if you just plucked a single gene and moved it into dairy cows? With gene editing, you could tweak dairy cows without messing up their finely tuned milk-producing DNA so that they would no longer have to endure dehorning. The Minnesota-based company Recombinetics tried this using a technique called TALENS (you might have heard of CRISPR this is just a different version of the same thing).

To run with the editing metaphor, Recombinetics basically took out the DNA that laid out instructions for HORN and replaced it with 202 letters of DNA that said HORNLESS. But first, they attached it to a bacterial plasmid think of it as a sub-cellular copy machine that would reproduce this strand over and over again (HORNLESS, HORNLESS, HORNLESS!). Then they injected all those copies into a cow cell that gave one of those copies a much better chance of bumping into the one spot in the DNA that read HORN. This is where things went wrong. Instead of just replacing HORN with HORNLESS, the plasmid also folded into the cells DNA so that it read something like HORNLESS-COPYMACHINE-HORNLESS. That genetic information went into an egg, which went into a cows uterus, and, in 2015, grew into a hornless calf. No one noticed until years later.

The calves I saw at Davis were there to be studied by Alison Van Eenennaam, an animal geneticist. Funded by a U.S. Department of Agriculture program to assess the risks of biotech, her team first verified that the hornless trait was being passed down through generations of cattle. Basically, we found that Mendel knew his shit, said Van Eenennaam (thats Gregor Mendel, the scientist from the 1800s who described how traits are inherited).

With this new paper, Van Eenennaams team showed that the bacterial plasmid had also been passed down to some of the calves, again following the rules of genetics 101. It doesnt seem to be causing a problem its fairly normal for DNA from germs and viruses to work its way into genomes (the human genome is about 8 percent virus DNA), and critters can usually just roll with it. But because these cattle had DNA from a bacteria, it meant they were genetically modified organisms, or GMOs in the eyes of government regulators. That, in turn, meant they would have to undergo years of testing. A giant corporation like Bayer could afford that, but not a small startup like Recombinetics. The FDA is now treating gene-edited animals like new drugs, requiring multiple rounds of safety testing, which effectively puts an end to the quest to make hornless dairy cows. Longtime opponents of biotechnology think that would be a good thing. Friends of the Earth recently released a report with Janet Cotter, who runs the consultancy Logos Environmental, condemning gene edited animals.

The scientific evidence shows that gene editing, particularly in animals, is far from precise. Cotter said in a statement. Instead, it can produce unintended changes to genetic material and disrupt genetic processes. Such effects could have far reaching consequences for food safety, so these applications will require a rigorous assessment if they are to be used in agriculture.

It would be easy enough to screen out plasmids before putting gene-edited eggs into a cows womb. Thats a routine procedure, said Van Eenennaam. But she worries that wont quell fears that gene editing is sloppier than expected. Treating gene-edited animals like drugs is not proportionate with the risk, Van Eenennaam said, and would prevent breakthroughs that might help us meet the challenge of climate change, whether its cows that dont belch methane, or corals that can survive heat., Van Eenennaam said.

The debate has pretty much blocked the technology in animals through my whole career. I was hoping gene-editing would be different, she said. I have students who are excited about gene editing for disease-resistance but now I feel like its Ground Hog Day. Here we go again.

As a nonprofit news outlet, we rely on reader support to help fund our award-winning journalism. Were one of the few news outlets dedicated exclusively to people-focused environmental coverage, and we believe our content should remain free and accessible to all. If you dig our mission and agree news should never sit behind a paywall, donate today to help support our work. Chip in what you can.

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Gene editing could help save the planet if scientists can avoid the typos - Grist

Death was conquered, via an elaborate cloning technique, and everything looked as if things were finally turning around for Charles Xaviers friends and foes.

And then Powers of X explicitly states that things will always turn out badly for mutants.

Its much worse than that. We always lose, Moira MacTaggart tells Xavier midway through the series, and she should know; by this point in the narrative, she has lived and died nine different times, trying alternative ways to maintain the survival of the mutant race without success. (As the final issue of Powers of X reveals, Moira has lived for a thousand years in one timeline and it still ended with the mutantkind being outstripped by a humanity augmented by its own invention.

Mutants are an evolutionary response to an environment. You are naturally occurring. The next step in human evolution, a character from 1,000 years in the future explains in the issue. But what happens when humanity stops being beholden to its environment? When man controls the building blocks of biology and technology Evolution is no match for genetic engineering. What good was one mutant adapting to its environment when we could make ten super men?

Turning the franchises long-running theme on its head, the core conflict of the X-Men property isnt homo superior (mutant) versus homo sapien (man), but homo superior versus homo novissima (post-human, or genetically engineered human) a battle that, its suggested, mutantkind will lose no matter what.

Armed with this knowledge, Moira has manipulated events throughout the franchise and certain people to try and equip mutantkind as best she can in the upcoming conflict, leading to a united Xavier and Magneto announcing that she has honed them into perfect tools for an imperfect age that would change things moving forward.

The new era of X-Men comics, therefore, is one in which the majority of characters believe that theyre living in a golden age of mutantkind, but theyre actually part of the latest in a series of conflicts for survival that they are, perhaps, destined to lose. How this thread will continue through the multiple Dawn of X spinoff titles remains to be seen, but with Powers of X author Jonathan Hickman writing the ongoing X-Men series launching in the wake of this reveal, one thing is for certain: This isnt an idea that is going to go away anytime soon.

Powers of X No. 6 is available now in comic book stores and digitally.

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Marvel's 'Powers of X' Ends With Surprising Revelation - Hollywood Reporter

This story is part of The 2010s: A Decade in Review, a series on the memes, people, products, movies and so much more that have influenced the 2010s.

The first decade of the 21st century introduced us to sweeping mobile and social revolutions largely driven by names like Jobs, Zuckerberg and Bezos. In the second decade that's now closing, things got a little more complicated. During those years, a new collection of faces have joined the earlier tech titans to continue moving us into the future. Here's CNET's list of the top technology innovators and all-around unavoidable personalities of the 2010s.

A person wears a Guy Fawkes mask, which today is a trademark and symbol for the online hacktivist group Anonymous. From 2012.

More a decentralized collective than a personality, Anonymous was the name claimed by the loose affiliation of hackers who brought "hacktivism" into the mainstream. During the first half of the decade, Anonymous launched attacks against targets like ISIS, the governments of the US and Tunisia, and corporations such as Sony and PayPal. The group's tactics included distributed denial-of-service attacks that overwhelm a target's website and knock it offline and compromising private databases to access and later leak confidential information, such as the personal details of members of the Ku Klux Klan.

In 2019, the group's prominence has faded somewhat -- last year it said it would debunk the QAnon conspiracy theory -- but concerns about hacking remain in the forefront, in part because one large collective of unknown activists put it there.

Julian Assange of WikiLeaks during a livestreamed press conference in 2017.

The founder of online portal WikiLeaks, Assange had a mission to reveal the secrets of the powerful. It made him an instant hero to many and a wanted man to others (in May the US government charged him with violating the Espionage Act). WikiLeaks started the decade by publishing documents obtained by whistleblower Chelsea Manning between 2010 and 2011, and it supported NSA whistleblower Edward Snowden after he sought refuge in Russia in 2013. To avoid extradition to Sweden on charges of rape -- the charges were dropped in 2017, but the case has since been reopened -- Assange took refuge in the Ecuadorian embassy in London, where he remained for seven years.

Despite its founder being stuck in the same building for much of the decade, WikiLeaks still managed to play a role in the 2016 US presidential election by publishing leaked emails that were detrimental to Hillary Clinton and the next year releasing thousands of documents showing how the CIA can hack into phones. The Assange saga is far from over, though. In 2019 he was booted from the embassy by the Ecuadorian government and arrested by London police. He remains in British custody and could be extradited to the US.

Now playing: Watch this: Step inside Julian Assange's office

3:25

GM CEO Mary Barra says the self-driving technology can help relieve driver stress.

The General Motors CEO became the first woman to lead a major carmaker when she took over in 2014 and has been consistently ranked among the world's most powerful women over the past decade by Forbes and Fortune.

Her tenure has been marked by GM's push to keep up and even eclipse Tesla's efforts to bring electric and driverless cars into the mainstream. The Chevy Volt EV actually brought a sub-$40,000 EV to market ahead of Tesla's Model 3, and GM has also invested in ride-sharing technology to help ensure it stays relevant in the future.

Under Barra, GM is also one of just two global businesses to completely do away with its gender pay gap, according to a study by Equileap.

Bezos speaking at an Amazon press event in 2018.

Even after losing a quarter of his Amazon shares in his divorce settlementin April, Bezos remains the world's richest person, worth more than $107 billion as of this month, according to Forbes. Throughout the decade, he spread his money around,buying the Washington Post in 2013 and growing his company phenomenally. Amazon is now a vast empire that's not only become the world's warehouse, but that also encompasses the Amazon Web Services cloud computing platform, game streaming platform Twitch, a fleet of freight aircraft, music streaming,branded convenience stores, the Kindle e-reader, the Whole Foods Market grocery chain and a space startup meant to give Elon Musk and SpaceX some competition. Its Prime subscription service delivers goods in hours, and serves up a huge gallery of movies, TV programs and audiobooks.

Amazon also makes plenty of products of its own, including its Alexa-powered home assistants and Ring security system, both of which have forced the company torespond to privacy concerns over its increasing expansion into homes. And the company continues to face criticism over working conditions and pay for its employees.

Now playing: Watch this: Jeff Bezos reveals plans for the moon and beyond

3:33

danah boyd

She may not be a household name, but danah boyd (who prefers to spell her name with lowercase) has become a leading thinker and researcher on the effects of technology on society and our children. In her 2014 book It's Complicated, she argued that social media provides an important space for youth to express themselves and to engage with each other and with society.

She's also a principal researcher for Microsoft and has broadened her research to focus on the relationship between social inequality and technology through her research institute Data and Society. In awarding her its 2019 Pioneer award, the Electronic Frontier Foundation called boyd a "trailblazing technology scholar."

Richard Branson at a Virgin Mobile event.

The billionaire magnate is willing to try just about anything, it seems. Branson's Virgin brand has dabbled in everything from media to hotels to health care, and in the last decade it has also made some far-out bets. In recent years, Branson has invested in Elon Musk's futuristic hyperloop transport technology and is working on Virgin Orbit, which could launch satellites using a combination of rockets and a high-altitude launcher plane. In the coming months, Virgin Galactic mayfinally begin launching tourists (including Branson himself) into orbit using a similar approach from the New Mexico desert.

By 2040, there will be 1 million more young women of color with coding skills if Kimberly Bryant meets her ambitious goal. The electrical engineer and Vanderbilt grad founded Black Girls Code in 2011 with the goal of reaching 1 million girls by midcentury. That could transform places like Silicon Valley, where only 2% of women working in tech are people of color, according to a 2018 report from the Kapor Center. Bryant's work has been widely recognized -- by the White House, the Smithsonian and others -- helping to bring in funding for the mission and increasing the chances that the next Steve Jobs is a woman of color.

Mark Cuban at CNET's Next Big Thing panel at CES 2013

During the 2010s, Cuban became much more than just one of the billionaires from the original dot-com boom of the late 1990s. He completed his crossover to become a major figure in the worlds of sports, entertainment and even politics.

Cuban's riches can be traced to successful exits from old, old-school internet properties like Broadcast.com, but he's since leveraged those early moves into a career as an NBA franchise owner, a TV personality (most notably on Shark Tank) and an investor in dozens of companies including Dropbox, Magnolia Pictures and Alyssa's Cookies. He was even floated as a potential presidential candidate in 2016 and 2020, but says he won't run without his family's permission.

Tim Cook at WWDC 2019.

It was a difficult job to take the mantle after Steve Jobs died in 2011, but Cook has maintained Apple's dominance over the past several years. Cook may not be the showman of his predecessor, but the brand is as far-reaching as ever. The iPhone still rules the mobile roost alongside Android, and under his guidance the company has launched forays into areas like the Apple Watch, content production, Apple Arcade and even finance with the Apple Card.

While it might be a stretch to call Cook a gay icon (he came out in a 2014 essay), he's certainly one of the most powerful LGBTQ people in the world, and his worldview has informed his drive to make Apple more ethical, diverse and values-driven, according to author Leander Kahney.

A pre-beard Dorsey.

Assuming the role of Twitter's CEO in 2015, Dorsey's been the face of one of the most highly trafficked and often toxic online platforms. Over the past decade, Twitter helped give rise to revolution in the Middle East, including the ouster of Egyptian President Hosni Mubarak, and also gave us the platform that @RealDonaldTrump has used more effectively than any other American politician to rally support and spin news events. Twitter has also enabled floods of hate speech, fake news and misinformation. Though the company has tried to combat them with new rules and technology, it's only subject to more criticism when the regulations are unevenly enforced.

As he tries to guide Twitter's central role in reshaping global media, Dorsey's also CEO of payments company Square, giving him an outsized influence in how information and money move around the world now and in the coming years.

Jennifer Doudna

One of the key innovations of the 2010s goes by the unwieldy name CRISPR/Cas9, and Doudna is a pioneer in its use to edit DNA. This new tool holds the potential to revolutionize biology, medicine, agriculture and other fields.

Doudna's lab at the University of California, Berkeley has also spun off a for-profit venture to commercialize CRISPR applications, and Doudna has become a leader in the ongoing ethical discussions around the future of genetic engineering.

Susan Fowler at the Women Transforming Technology conference

The #MeToo movement swept through the tech world and other industries beginning in 2017, thanks in large part to Fowler's personal blog chronicling sexual harassment and abuse within Uber, where she worked as a software engineer. The fallout resulted in a shakeup of Uber's power structure and the demotion of founder and CEO Travis Kalanick. Fowler's memoir, Whisteblower, is due out in 2020, and she has a new role writing for the New York Times opinion section.

This power couple has taken the money that Bill made producing the software suites we all love to complain about and turned it into a philanthropic empire. The $50 billion Bill and Melinda Gates Foundation has poured millions into global health and development efforts, as well as education in the US. Bill says the foundation played a major role in a drastic reduction of the child mortality rate, saving over 100 million lives. Bill has also stayed relevant through the reading lists he releases regularly, and Melinda debuted as an author herself with a book about empowering women around the world.

Elizabeth Holmes in a still from The Inventor: Out for Blood in Silicon Valley.

Like Pixelon's Michael Fenne (real name: David Kim Stanley) almost two decades earlier, Holmes serves as a cautionary tale for what can go wrong when the hype becomes unmoored from reality in tech.

In the span of a few years, Holmes took Theranos and a never-quite-ready-for-primetime blood-testing technology from a subject of interest to one of investment, investigation and now, potentially Holmes' own incarceration as she faces charges of criminal fraud.

The decade began with Jobs' introduction of the iPad in January 2010, nearly two years before he died in October 2011. Apple, whose iPhone helped change the way we live, has continued to be one of the most iconic and valuable brands in the history of capitalism. His legacy has been a topic of near constant discussion since his passing, including treatments in multiple Hollywood movies and major books from the likes of Walter Isaacson and Jobs' daughter Lisa Nicole Brennan-Jobs.

John Legere

T-Mobile's CEO could be the most interesting person in the wireless industry. Over the past decade, he's masterfully played the role of underdog fighting against telecom giants like AT&T and Verizon. Nearly everything the exec does seems calculated to turn heads, whether it's lacing a press conference with profanity, launching barbs at the competition on social media or dressing in the company's trademark magenta. But Legere also produced results, greatly increasing T-Mobile's customer base over the years, revamping the carrier's customer service and bucking industry trends by keeping unlimited data plans. Despite it all, Legere's future going into 2020 is uncertain, with talk he might be replaced should a pending merger with rival Sprint finally go through.

Travis Kalanick exits federal court after taking the stand during the Waymo v. Uber trial over allegedly stolen driverless car trade secrets.

The Uber founder embodies the success-at-all-costs mentality that has driven many other Silicon Valley success stories. He led a ride-sharing revolution that quickly spread around the world and made Uber the prototypical startup "unicorn." But allegations of sexual harassment (brought by whistleblower and engineer Susan Fowler) and Kalanick's own abrasive leadership style would soon see him pushed out as the company's leader in June 2017, although he still retains a seat on the board.

Tesla CEO Elon Musk

Musk wants to save the planet with electric cars and solar panels, take us to Mars, connect our brains to computers and shoot us around the world in pressurized tubes at near the speed of sound with his hyperloop-creating Boring Company. Most of this visionary's big visions are still in progress, but his credibility comes from simultaneously disrupting both the automotive and commercial space industries over the past decade with the success of Tesla and SpaceX. The world tends to watch his every move, which he often gleefully shares on social media. Musk's tweets have brought him trouble, especially when they move Tesla's stock price and invite lawsuits and the ire of the SEC or appear to smear a diver trying to rescue a Thai soccer team trapped in a cave.

Microsoft CEO Satya Nadella speaks at a company event.

This Indian immigrant with a degree in electrical engineering turned out to be the right man for the job of making Microsoft cool again. Or at least making it cooler. Since becoming CEO in 2014, Nadella has helped increase Microsoft's bottom line and make it a trillion-dollar company. He's overseen a transformation that has done away with the company's cutthroat reputation, both toward competitors and internally, though in 2014 he apologized after making controversial comments about women's pay in an interview. Nadella has also advanced forward-looking acquisitions in artificial intelligence, gaming and brand names like Github, LinkedIn and Mojang, creator of Minecraft.

Very few people seem to know who Nakamoto really is. The presumed pseudonym is attached to the person or persons responsible for the development of bitcoin, which launched a cryptocurrency revolution that started slowly in 2009 but picked up steam over the decade that followed.

A once-worthless digital currency, bitcoin has been valued at up to $20,000 per coin. It inspired the development of countless other cryptos and an entirely new industry around its underlying technology, blockchain. Although some have claimed to be the real Nakamoto and others have been falsely outed as the actual Satoshi, his true identity remains unclear.

Google CEO Sundar Pichai

Google has gone from "Don't be evil" to increasingly having to convince consumers and regulators that it isn't. When the company transformed into Alphabet in 2015 and the Google name was attached to its internet-focused subsidiary (including Android, YouTube and search), Pichai became the new face of Google as CEO. During his first four years, the Googleplex has continued to dominate everything from search to mobile operating systems to online cat videos, while making big moves with new hardware like Google Home and a fleet of Pixel devices. It hasn't been all sunshine, though. Pichai has also had to navigate the proliferation of hate speech and disinformation on YouTube, deal with walkouts over sexual harassment allegations directed at Google executives and confront criticism over a possible censored search service in China. That's to say nothing of the James Damore saga over the company's diversity policies. Still, Pichai and Google seem likely to remain on top for the foreseeable future.

Zoe Quinn.

Years before #MeToo, Gamergate gave us all a preview of the widespread bad behavior and abuse by people in positions of power that would soon be exposed across a number of industries. Quinn, along with fellow game developer Brianna Wu and culture critic Anita Sarkeesian, was among the first to be harassed and threatened by mobs of online trolls that would eventually coalesce around the #gamergate hashtag. It was an early warning sign of how bad things would become online.

Quinn, who uses they/them pronouns, turned their experience and insights into the 2017 book Crash Override: How Gamergate (Nearly) Destroyed My Life, and How We Can Win the Fight Against Online Hate. They have continued to be vocal about instances of abuse within the gaming industry while also churning out new comics (for both Marvel and DC) and collaborating on indie games.

IBM CEO Gini Rometty

CEO of IBM is another job title that doesn't seem as cool as it was 50 years ago. But since taking over in 2012, Rometty has moved the company from dinosaur status to focusing on the future. IBM today is invested deeply in nascent technologies like artificial intelligence, blockchain and quantum computing.

Sheryl Sandberg in 2015.

Sandberg was the fresh face Facebook often needed when Mark Zuckerberg spent too much time in the spotlight. While she deserves some credit for building Facebook up to the global force it is today, her 2013 business and leadership memoir Lean In made her a household name. Facebook and Sandberg have since received a healthy dose of criticism for the platform's myriad scandals, ranging from privacy concerns to the spread of misinformation, but they continue to stand their ground.

Former Instagram executive Adam Mosseri, flanked by Mike Krieger on the left and Kevin Systrom on the right.

As social media scandals increasingly give platforms like Facebook and Twitter a bad rep, Instagram seems to remain an almost-pristine place for all our best moments, no matter if they're earnest or fake AF, a la Fyre Festival. The disastrous music festival was promoted using Instagram and harnessed the power of its many "influencers" and the FOMO it engenders perhaps better than any other platform. Systrom and Krieger co-founded the photo-sharing site in 2010 and the service was snapped up by Facebook in 2012 for $1 billion. Systrom stayed on as CEO through 2018, growing the service to almost a billion registered users. While the platform has faced criticism over censorship in several countries and other practices like "shadowbanning" (in which posts are hidden from the view of others without it being apparent to the user), Instagram has remained relatively scandal-free compared to its parent company in recent years.

Peter Thiel in 2014.

Like Musk, Thiel made his first big pile of money from the sale of PayPal, which he co-founded, to eBay in 2002. The hits continued when he became Facebook's first outside investor in 2004 and went on to make early investments in Airbnb, LinkedIn, Yelp, Spotify and SpaceX, just to name a few.

Over the past decade, though, he's become better known for his political and social stances, particularly his growing disdain for Silicon Valley and his fervent support of President Trump. He also backed a lawsuit filed in 2012 over wrestler Hulk Hogan's sex tape that ultimately bankrupted gossip site Gawker, allegedly over a grudge he held against the site for a 2007 article outing him as gay. Thiel's Libertarian views have also inspired projects like the Seasteading Institute, which aims to create a society at sea, beyond the reach of any government.

Desktops are still alive and kicking, according to HP CEO Meg Whitman.

The former CEO behind the early growth of eBay is always doing something interesting. After losing a bid for governor of California in 2010, Whitman spent the first half of the decade leading and splitting up Hewlett-Packard into two businesses. After leaving HP in 2017, she turned her energies to new efforts focused on younger consumers than the typical HP customer. She's now CEO of upcoming short-form video service Quibi and an investor and board member at Los Angeles esports startup Immortals.

Mark Zuckerberg discusses Oculus at an event last month.

The decade opened with Jesse Eisenberg playing Zuck in the 2010 film The Social Network, and in recent years the Facebook founder probably would have been happy to have an actor continue to play him as CEO. As we've debated the power of Facebook and how much it knows about us, Zuckerberg has confronted multiple scandals and sat for hours of grilling by Congress over the proliferation of fake news on his platform. Through it all, Facebook has arguably been at the center of everything during the past 10 years, whether it's influencing the Brexit vote and the 2016 presidential election or the revelations that data research firm Cambridge Analytica had harvested the data of millions of Facebook users without their consent. Now presidential candidates talk of breaking up the social networking behemoth even as Zuckerberg hopes to move forward into the brave new world of VR with the help of companies like Oculus that it has swallowed over the past decade.

Originally published Oct. 10, 5 a.m. PT.

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From Elon Musk to Jeff Bezos, these 30 personalities defined the 2010s - CNET

The word agriculture conjures up an array of images: endless fields of corn stalks, amber waves of grain, the deserts of Africa Africa? While thoughts of the African landscape may tend to invoke a dry and empty countryside, scientists at Washington University in St. Louis are working to develop self-sustaining plants that could eventually turn the Sahara into a sea of green.

Himadri B. Pakrasi, the Glassberg Greensfelder Distinguished University Professor in the department of biology in Arts & Sciences and director of the International Center for Energy, Environment and Sustainability (InCEES), and Costas D. Maranas, professor of chemical engineering at Penn State, were recently awarded a $1.2-million grant from the National Science Foundation for their collaborative study of systems biology. Specifically, the Pakrasi and Maranas labs hope to decode the inner workings of cyanobacteria for the ultimate purpose of producing nitrogen-fixing crop plants.

For more than a century, farmers around the world have relied heavily on chemical fertilizers to help grow their plants and crops. Fertilizers contain nitrogen, an essential building block for all life forms to grow, and an element that is abundant in the earths atmosphere. However, creating man-made fertilizers is an energy intensive process that contributes to greenhouse gases and leads to run-off issues that severely damage the environment. A solution to this problem is to engineer plants to absorb nitrogen from the atmosphere and convert it into fertilizer, a process known as nitrogen fixation, so that the plants would become self-sufficient.

If you have engineered seeds that you give to an African farmer, that farmer can then plant the seeds, which gives rise to a field of crops that would not need chemically synthesized fertilizer to grow, Pakrasi said. This has huge agricultural implications not just for the affluent, Western world,but to the areas hardest hit by climate change.

Easier said than done. Nitrogen fixation cannot take place in the cells of most photosynthetic organisms plants that convert sunlight into energy because when plants are undergoing photosynthesis, a byproduct is oxygen. And oxygen is like a poison when it mixes with nitrogenease, the enzyme that enables nitrogen fixation. However, there is an organism that can accommodate both photosynthesis and nitrogen fixation in the same cell: cyanobacteria.

Just like human beings, cyanobacteria have a robust circadian rhythm a 24-hour biological cycle during which they photosynthesize in the day and fix nitrogen at night. Scientists have long studied these bluish-green creatures, but do not have a detailed understanding of how circadian rhythms allow cyanobacteria to adjust its metabolism for both nitrogen fixation and photosynthesis to take place in the same cell. With advances in genetic modification tools, it is now possible to probe deeper into the details of this process.

There are still missing parts of the cyanobacterial puzzle, Pakrasi said. The only way to identify what those missing parts are is to actually go into the cyanobacterium and tease apart the machinery. And thats what this grant will allow us to do.

In other words, the Pakrasi lab will perform a series of genetic modifications to the cyanobacteria and generate new data. The Maranas lab will then take the data and develop a predictive model for the inner working of the cyanobacterium. This iterative process will take some time, but the research is imperative to combating the climate changes facing the planet, Pakrasi said.

Its kind of like building an electric pickup truck, Pakrasi said. How do you go from a gasoline fueled car to a Tesla pickup truck? The basic technology for making a gas fueled car is already known, but were moving to a new paradigm of production in the form of a Tesla truck. Once we figure it out, we can deploy the new technology to our partners all over the world.

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NSF funds research on nitrogen fixation - Washington University in St. Louis Newsroom

(MENAFN - GetNews) According to report published by Grand View Research,Growing number of approved companion diagnostics and biomarker products have been proved promising avenues for the development of advanced precision diagnostic tests. Several personalized diagnostics and therapeutic products based on companion diagnostics are under clinical trials and development pipelines, which also add an incremental opportunity to accelerate this market.

According to a report, ' Personalized Medicine Market Size, Share & Trends Analysis By Product (Personalized Medical Care, Therapeutics, Personalized Nutrition & Wellness), By Region (Asia Pacific, Europe, North America), And Segment Forecasts, 2019 - 2025 , published by Grand View Research, Inc., The global personalized medicine (PM) market size is expected to reach USD 3.18 trillion by 2025 registering a CAGR of 10.6% over the forecast period, according to a new report by Grand View Research, Inc. Growing number of approved companion diagnostics and biomarker products have been proved promising avenues for the development of advanced precision diagnostic tests. Several personalized diagnostics and therapeutic products based on companion diagnostics are under clinical trials and development pipelines, which also add an incremental opportunity to accelerate this market.

Gene therapies are widely utilized to diagnose both chronic and genetic disorders according to individual's genetic makeup. Growing adoption of gene sequencing and data analytics technologies is anticipated to escalate precision medicine market growth. Decreasing cost of whole genome sequencing, advancement in cell biology sector, and the development of 'Human Genome Project are several other factors influencing the demand for gene therapy hence, boosting the overall market. Moreover, key leaders are undergoing numerous strategic developments to launch novel personalized products, which will also contribute to the market expansion.

For instance, in September 2018, Vertex Pharmaceuticals collaborated with Genomics for the delivery of precision medicine based on individual's genetic differences and lifestyle. Similarly, in January 2018, Foundation Medicine collaborated with European Organization for Research and Treatment of Cancer (EORTC) to facilitate Foundation's comprehensive genomic profiling to across personalized medicine and clinical trial enrolment.

Further key findings from the study suggest:

PM therapeutics is projected to register the fastest CAGR over the forecast period owing to the development of high-capacity rapid sequencing platforms for medical therapies

Reduction in sequencing cost leads to an expected growth of genomic sequencing and genetic research, thus contributing to lucrative opportunities for genomic medicine

Asia Pacific is projected to be the fastest-growing regional market due to rising number of collaborative initiatives between eastern and western market leaders

Chinese personalized medicine market is benefitted due to initiatives implemented by the Chinese government and reimbursements for disease treatment

Prominent companies include GE Healthcare; Illumina, Inc.; Asuragen, Inc.; Abbott Laboratories; Dako A/S; Exact Science Corp.; and Biogen, Inc.

Product Insights

Personalized nutrition & wellness was the largest product segment in 2018. Availability of a wide range of nutrition & wellness products and increased Over The Counter (OTC) sale of these productsplay a significant role in boosting the segment growth. Companies are undertaking several initiatives for sustaining market competition. For instance, in March 2018, DSM partnered with Mixfit to provide personalized nutrition solutions by combining Artificial Intelligence (AI) technology.

This strategic partnership was targeted towards offering consumers a personalized approach regarding nutrition. PM therapeutics includes pharmaceuticals, genomic medicine, and medical devices for personalized therapies and it is anticipated to witness the highest CAGR during the forecast period. Advent of high-capacity rapid sequencing platforms and reducing cost of sequencing whole human genome plays a major role in the segment development.

Genomic medicine has emerged as a significant segment in PM therapeutics. Availability of large databases of genomic data enables researchers to develop accurate and effective therapeutic products for several medical conditions. Consequently, this results in high utilization of human genome sequencing techniques for genomic medicine.

Regional Insights

Led by U.S., North America was the dominant regional personalized medicine market in 2018. Increasing adoption of NGS methods and healthcare IT systems in clinical workflow along with supportive government policies and funding drives the regional market.

For instance, in September 2018, the All of Us Research Program initiated by the National Institutes of Health (NIH) awarded funds of USD 28.6 million to three genome centers of the U.S. This funding supported the generation of genomic data from biosamples by these centers, which is a critical component of precision medicine discoveries.

Ask Our Industry Expert for More Details on Report -https://www.grandviewresearch.com/inquiry/625/ibb

However, Asia Pacific is projected to witness the highest CAGR over the forecast period owing to low cost of clinical trialsof newly developed precision medicines and diagnostic products. Moreover, rising disposable income levels and growing economy of emerging countries will boost the market further.

Browse Related Report:

Grand View Research has segmented the global personalized medicine market on the basis of product and region:

Personalized Medicine Product Outlook (Revenue, USD Million, 2014 - 2025)

Personalized Medicine Regional Outlook (Revenue, USD Million, 2014 - 2025)

Explore the BI enabled intuitive market research database, Navigate withGrand View Compass , by Grand View Research, Inc.

About Grand View Research

Grand View Research provides syndicated as well as customized research reports and consulting services on 46 industries across 25 major countries worldwide. This U.S.-based market research and consulting company is registered in California and headquartered in San Francisco. Comprising over 425 analysts and consultants, the company adds 1200+ market research reports to its extensive database each year. Supported by an interactive market intelligence platform, the team at Grand View Research guides Fortune 500 companies and prominent academic institutes in comprehending the global and regional business environment and carefully identifying future opportunities.

Media Contact Company Name: Grand View Research, Inc. Contact Person: Sherry James, Corporate Sales Specialist - U.S.A. Email: Send Email Phone: 1-415-349-0058, Toll Free: 1-888-202-9519 Address: 201, Spear Street, 1100 City: San Francisco State: California Country: United States Website: https://www.grandviewresearch.com/industry-analysis/personalized-medicine-market

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Personalized Medicine Market Is Estimated to Cross USD 3.18 Trillion By the End of 2025 | Grand View Research, Inc. - MENAFN.COM

ARTIFICIAL INTELLIGENCE

How to Stop Superhuman AI Before It Stops UsStuart Russell | The New York TimesOnce the focus shifts from building machines that are intelligent to ones that are beneficial, controlling them will become a far easier feat. Consider it the difference between nuclear power and nuclear explosions: a nuclear explosion is nuclear power in an uncontrolled form, and we greatly prefer the controlled form.

This Girls Dramatic Story Shows Hyper-Personalized Medicine Is Possibleand CostlyErika Check Hayden | MIT Technology Reviewin a dramatic demonstration of the power of personalized medicine, doctors in Boston created a treatment just for [six-year-old Mila Makovec]. In only eight months, they found the genetic cause of Milas disease, designed a drug to overcome the error, and began giving it to Mila via an injection in her spine, in whats believed to be the first individually tailored treatment of its kind.

Waymo Tells Customers That Completely Driverless Vehicles Are on the WayAndrew J. Hawkins | The VergeIts a sign that Waymo is growing confident enough in its technology to increase the frequency at which it allows passengers to ride in autonomous vehicles without a safety driver behind the wheel.

Virgin Orbit Says It Wants to Send Tiny Spacecraft to Mars in 2022Neel V. Patel | MIT Technology ReviewIf it succeeds, Virgin Orbit will be the first commercial company to travel to the Red Planet. It will also mark an unexpected entrance into deep spaceflight for a company whose plansfocus on air launches, which have always been considered unsuitable for traveling beyond low Earth orbit.

Jeff Bezoss Master PlanFranklin Foer | The AtlanticWhere in the pantheon of American commercial titans does Jeffrey Bezos belong? At 55, Bezos has never dominated a major market as thoroughly as any of these forebears, and while he is presently the richest man on the planet, he has less wealth than Gates did at his zenith. [But] the scope of the empire the founder and CEO of Amazon has built is wider. Indeed, it is without precedent in the long history of American capitalism.

Meet the Robot Racing Drone That Could Beat Human Pilots by 2023Stephen Shankland | CNETSince 2016, the human pilots of theDrone Racing Leaguehave competed to see who could whip a quadcopter around pylons and through hoops the fastest. On Tuesday, theyll get a new challenge: the fully autonomous RacerAI, adroneprogrammed to fly itself.

Image Credit:MEAX /Unsplash

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Novartis is soliciting proposals from patient advocacy organizations for initiatives designed to expand and improve understanding of biomarker testing among people with cancer that are based on the pharma giants Solutions to Empower Patients (STEP) Program.

The STEP Program will fund up to four patient advocacy organizations as much as $75,000 each, with the aim of helping them address education, access, and reimbursement challenges like those that have hindered the development and use of biomarker testing in personalized medicine, Novartis said.

The deadline for submissions is 11:59 on November 4, 2019.

By supporting patient advocacy organizations that empower patients and their care teams to make informed decisions about their health, the STEP Program can help create a path to better care, Ameet Mallik, Executive Vice President and Head, US, Novartis Oncology, said in a statement.

Created in 2017, the STEP Program has helped fund the patient-focused initiatives of eight organizations nationwide. The STEP program funded three organizations in 2017 and five last year.

Novartis says it created the STEP Program with the intent of supporting U.S.-based nonprofit organizations as they work to address some key challenges in healthcare. Any national, US-based, 501(c)(3) patient advocacy organization is invited to submit a STEP Program proposal that focuses on at least one of the following criteria in cancer biomarker testing: Awareness and Education, Self-Advocacy, and/or Policy Improvement.

Proposals will be evaluated by an external review committee consisting of experts in a variety of fields. The committee will review the applications and identify as many as four proposals deemed to have the potential to make the greatest positive impact on the cancer community, Novartis said.

All organizations will be notified of the review committees decision by or before January 31, 2020.

Novartis said organizations interested in details on how to submit proposals, or which want to learn more about the STEP program, should visit the STEP Program page on the companys U.S. website.

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Novartis Solicits Proposals to Advance Biomarker Testing in Cancer - Clinical OMICs News

BALTIMORE, Oct. 11, 2019 /PRNewswire/ -- The African American Neuroscience Research Initiative (AANRI) announced today the receipt of a $275,000 grant from the Abell Foundation, which will provide critical funds to support the development and growth of the collaboration between the African American Clergy Medical Research Initiative and the Lieber Institute for Brain Development. Utilizing the Lieber Institute's robust brain repository, the AANRI aims to establish a road map to help close the gap in health disparities and accelerate research efforts that will lead to new treatments for brain disorders.

The Abell Foundation grant will enable the AANRI to establish a Scientific Advisory Committee, expand partnership and collaboration efforts, and hold an inaugural national meeting on the topic next year.

Also, last month U.S. Senator Ben Cardin (D-MD) championed report language through the Senate Appropriations Committee which officially recognizes the longstanding disparity in neuroscience research among underrepresented minority groups, including African Americans. The Committee urges the National Institute on Minority Health and Health Disparities to support the increase in neuroscience research among ethnically diverse individuals, including African Americans, and collaboration with external partners to develop the framework needed to advance the discovery of treatments for neuropsychiatric disorders which is the scientific goal and objective of the AANRI.

Senator Ben Cardin, senior senator for Maryland, said, "I'm proud to partner with the AANRI and the Lieber Institute for Brain Development to address this long-standing disparity in neuroscience research. Working together, we can correct this inequity and accelerate the discovery of treatments that benefit ethnic minority groups, including African Americans."

Rev. Dr. Alvin C. Hathaway, Sr., Principal of the African American Clergy Medical Research Initiative, said, "My clergy colleagues and I have been studying the emerging science behind precision medicine and believe that this technology has potential for finding cures and treatments for diseases that uniquely affect African Americans. This grant brings us one step closer to ensuring ethnic minority groups are not left behind in the precision medicine revolution. And the efforts of Senator Cardin if realized will be transformative."

The AANRI addresses a long-time disparity. While genomic research has the potential to provide some of the most personalized and effective medical treatments for many medical disorders, minority groups are inadequately represented in these large-scale genomic studies. In neuroscience research studies of brain disorders, underrepresented minority groups, including African Americans, make up less than 5% of research cohorts.

"So far, personalized medicine has not really been for everyone," said Daniel R. Weinberger, M.D., Director and CEO of the Lieber Institute. "The Abell Foundation grant provides critical support to enable the AANRI to execute the scientific strategy, with the ultimate goal of developing new treatments for brain disorders for people of African ancestry."

For more information on the African American Neuroscience Research Initiative, visit aaneuroscience.com or contact Becky Oldham, Director of Communications at the Lieber Institute for Brain Development at media@libd.org.

About the African American Neuroscience Research InitiativeThe African American Neuroscience Research Initiative (AANRI) aims to establish a road map to help close the gap in health disparities and accelerate research efforts that will lead to new treatments for brain disorders. The Initiative is the first of its kind in the nation to address health and neuroscience research disparities.

About the African American Clergy Medical Research InitiativeThe African American Clergy Medical Research Initiative (AACMRI) is focused on ensuring that persons of African descent are equitably represented in medical research. It advocates for equity in public policy, funding, education, training, and awareness that produces improvements in protocols, treatments, medicines and health outcomes.

About the Lieber Institute for Brain DevelopmentThe mission of the Lieber Institute for Brain Development and the Maltz Research Laboratories is to translate the understanding of basic genetic and molecular mechanisms of developmental brain disorders into clinical advances that change the lives of affected individuals. LIBD is an independent, not-for-profit 501(c)(3) organization and a Maryland tax-exempt medical research institute affiliated with the Johns Hopkins University School of Medicine.

About the Abell FoundationThe Abell Foundation is dedicated to the enhancement of the quality of life in Maryland, with a particular focus on Baltimore. The Foundation places a strong emphasis on opening the doors of opportunity to the disenfranchised, believing that no community can thrive if those who live on the margins of it are not included.

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African American Neuroscience Research Initiative Awarded Grant From Abell Foundation for Critical Program Support - P&T Community