StemCell Therapy

CYP1A1*2C A4889Grs1048943CTT-/-CYP1A1*4 C2453Ars1799814TGG-/-CYP1A2 C164Ars762551CAC+/-CYP1B1 L432Vrs1056836CCG+/-CYP1B1 N453Srs1800440CTT-/-CYP1B1 R48Grs10012CGG-/-CYP2A6*2 A1799Trs1801272TAA-/-CYP2C19*17rs12248560TCC-/-CYP2C9*2 C430Trs1799853TCC-/-CYP2C9*3 A1075Crs1057910CAA-/-CYP2D6 S486Trs1135840GGG+/+CYP2D6 T100Crs1065852AGG-/-CYP2D6 T2850Crs16947AAA+/+CYP2E1*1B G9896Crs2070676GCC-/-CYP2E1*4 A4768Grs6413419AGG-/-CYP3A4*1Brs2740574CTT-/-CYP3A4*3 M445Trs4986910GAA-/-CYPs are primarily membrane-associatedproteins located either in the inner membrane ofmitochondriaor in theendoplasmic reticulumof cells. CYPs metabolize thousands ofendogenousandexogenouschemicals. Some CYPs metabolize only one (or a very few) substrates, such asCYP19(aromatase), while others may metabolize multiple substrates. Both of these characteristics account for their central importance inmedicine. Cytochrome P450 enzymes are present in most tissues of the body, and play important roles inhormonesynthesis and breakdown includingestrogenandtestosteronesynthesis and metabolism,cholesterolsynthesis, andvitamin Dmetabolism. Cytochrome P450 enzymes also function to metabolize potentially toxic compounds, includingdrugsand products of endogenous metabolism such asbilirubin, principally in theliver.rs762551 (C) allele is a slow metabolizer or of certain substrates including caffeine which means Im more stimulated by it than most people.rs1056836 increases susceptibility to lung and breast cancer, blocks testosterone and inhibits mitochondrial function.rs1135840 is involved in the metabolism of approximately 25% of all medications and most psych meds including antipsychotics and antidepressants.GPX3rs8177412CTT-/-GSTM1rs12068997TCC-/-GSTM1rs4147565AGG-/-GSTM1rs4147567GAA-/-GSTM1rs4147568ATT-/-GSTM1rs1056806TCC-/-GSTM1rs12562055ATT-/-GSTM1rs2239892GAA-/-GSTP I105Vrs1695GAG+/-GSTP1 A114Vrs1138272TCC-/-GSTP genes encode the Glutathione S-transferase P enzyme. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of manyhydrophobic and electrophilic compounds with reducedglutathione. Mutations here will increase your need for glutathione and importance of chelating out mercury.rs1695 influences asthma risk.NAT1 A560G(?) (R187Q)rs4986782AGG-/-NAT2 A803G (K268R)rs1208GGG+/+NAT2 C190T (R64W)rs1805158TCC-/-NAT2 G590A (R197Q)rs1799930AGG-/-NAT2 G857A (G286E)rs1799931AGG-/-NAT2 T341C (I114T)rs1801280CCC+/+NAT2 encodes N-acetyltransferases which are enzymes acting primarily in the liver to detoxify a large number of chemicals, includingcaffeineand several prescribed drugs. The NAT2 acetylation polymorphism is important because of its primary role in the activation and/or deactivation of many chemicals in the bodys environment, including those produced by cigarettes as well as aromatic amine and hydrazine drugs used medicinally. In turn, this can affect an individualscancerrisk.I have a particular combination of NAT2 polymorphisms rs1801280 (C) +rs1208 (G) which makes me a slow metabolizer. In general, slow metabolizers have higher rates of certain types ofcancerand are more susceptible to side effects from chemicals (known as MCS) metabolized by NAT2.SOD2rs2758331AAA+/+SOD2rs2855262TCT+/-SOD2 A16Vrs4880GGG+/+SOD2 gene is a member of the iron/manganesesuperoxide dismutasefamily and may be one of the key sources of my troubles. This protein transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain, intohydrogen peroxideand diatomicoxygen. In simpler terms, the more energy your mitochondria produce, the more byproducts (also called free radicals) get produced. These toxic byproducts tear up cell membranes and walls through a process called oxidative stress.Mutations in the SOD2 gene diminish your ability to transform these toxic byproducts into harmless components. People with SOD2 polymorphisms may not tolerate nitrates or fish oil well. Mutations in this gene have been associated withidiopathic cardiomyopathy(IDC), sporadic motor neuron disease, and cancer.

Now what about SOD1 & 3? I dont know why it doesnt appear on this report but I was able to get some information on it from Livewello and it looks like I am much better off there. Heres my SOD1 and SOD3 status. Just for kicks, I decided to run SOD2 and I find it shows a much different picture than sterlings app: my SOD 2 on Livewello. Notice how it shows that I do have some working SOD2 genes!

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My genetics - How I Recovered

Biotechnology Careers At-a-Glance

The United States leads the pack in biotech revenue, market capitalization, and the number of public biotech companies, according to a 2015 report by Ernst & Young Global Limited. In 2007, three biotechnology companies made more than one billion dollars; by the end of 2014, that number had grown to 26, and there is no end in sight to the massive growth. Biotechnology careers can be found mainly in pharmaceutical companies including Gilead Sciences, Celgene, Biogen, and Regeneron, all companies named by Forbes among the top 10 biotech companies in the country.

People who choose biotech careers have several areas of specialization to choose from. A few options include working as an epidemiologist, microbiologist, biochemist, botany specialist, agricultural and food scientist or biomedical engineer. Graduates might wind up working in a laboratory, creating new seed lines, or in a vast field, testing new soil compositions. They might work to clone animals, develop new pharmaceutical drugs, create a bionic pancreas and so much more. No matter what the career path, it all begins with rigorous study and earning a biotechnology degree.

As with all statistics, salary numbers can be deceiving. There are two reasons why the numbers below should be taken into context.

First, biotechnology careers typically require a bachelors degree for entry, but the field is filled with people who also hold masters and doctoral degrees. For instance, 45 percent of the biomedical engineers who responded to an O*NET survey said a bachelors degree was sufficient; thirty-five percent needed a masters degree and a further 20 percent needed a doctorate. Those with advanced degrees typically have higher earning potential, which partially explains how some biomedical engineers can earn around $50,000 per year while others are clearing $140,000.

Second, there are multiple employers of the scientists listed below. Some of the most prominent are universities, which typically pay less than companies engaged in applied research. Companies make profits, which can be shared with employees; universities do not.

Working in the biotechnology field starts with the proper education. Though there are numerous pathways to the various professions, some steps to success are universal. Heres how to get there.

1

Begin with the right classes

Those interested in biotechnology careers can begin their journey by taking several biology or chemistry electives while in high school. Students should also look into pursuing courses that provide both high school and college credit, such as advanced placement.

2

Start with the bachelors degree

Once high school is over, its time to move into college and earn a bachelors degree in biology, biotechnology (if offered) or a closely related field. Though there are associate degrees in biology that will form a firm foundation for the bachelors, most entry-level positions in biotechnology will require at least a bachelors degree.

3

Get experience

Learning about the job and getting hands-on training in the field can look great on a resume, as well as provide students an opportunity to decide what area of biotechnology interests them the most. Some students choose internships during their college years, while others seek out part-time or full-time work with biotech companies or labs.

4

Pursue graduate studies

In many cases, biotechnology careers will require a graduate degree for advancement. Depending upon the chosen career path, students might need to embark on their masters degree or end up with a PhD in order to do the work they really want to do.

5

Stay up-to-date

Technology is always changing, growing and shifting. Some fields of biotechnology are moving so fast that they can literally change by the week. Thats why it is so important to stay up-to-date by subscribing to industry publications, becoming active in industry associations, keeping in touch with network contacts, and otherwise staying on top of what is happening in the field.

6

Seek out new opportunities in the field

Biotechnology careers offers quite a bit of overlap; for instance, a soil and plant scientist might choose to eventually work as an agricultural and food scientist, and their education might support both paths. Seeking out new opportunities to expand on a current profession is one of the perks of working in the field, and can lead to exciting possibilities.

Those who are interested in biotechnology will discover a dizzying array of possibilities for degrees; anything from the certificate to the PhD can be helpful during the career pursuit. In addition, many biotech degrees easily adapt to online study for students who dont have the ability to attend traditional classes. Heres an overview of which degrees might be more advantageous for certain situations.

I am excited to begin work in biotechnology. I need something that will allow me to get my foot in the door while giving me a strong foundation for graduate work.

I have been working in the field for years, but there are some points that I need to brush up on times have definitely changed these last few years, and Im ready to change with it. But leaving my job to go back to school is simply not an option, as finances would be too tight.

I already have my bachelors degree, but none of my classes focused on the high-level biology I need to know in order to move into the biotech field. I need to get a bit more education while I gain experience.

I definitely want to go into biotech but I have no idea where to begin. I want to test the waters a bit and leave my options open for changing my degree path when I find what I really want to do

I grew up on a farm and love working with animals. I want to be an animal scientist, so I can help make their lives better. Its a journey that will take some serious time and effort, but Im ready for the challenge.

Ive been working in the field for a while, but promotions and pay raises seem rather elusive one manager pointed out that my educational level is holding me back. Its time to remedy that problem.

Choosing the best biotechnology degrees can be tough, as there are so many options out there. However, the desired career path often provides clues to which degree might be best, as well as which level of educational attainment is expected. Heres what students can expect to learn from each.

There are two types of biotechnology certificate programs: Those that are designed for students who have completed their graduate studies and now need more specialized training, or those who have earned their bachelors degree but didnt get all the recommended courses to move into a biotech career. The latter scenario often applies to those who have earned their bachelors in another field but have now chosen a career change to the biotechnology field.

Most certificate programs take a year or less to complete, and are very focused on the particular educational path, with little to no general education courses. Some of the common courses in a certificate program include:

This course helps students understand structural organic chemistry, chemical thermodynamics, acid base chemistry, and reaction mechanisms.

Understanding of Lewis structures

Strategic use of reaction mechanisms

Knowledge of biological molecules and how they form and interact

Students will explore the ethical issues in biotechnology, including real-world case studies and current events in the field.

Applying philosophical theories to critical current issues

Conducting human experimentation in a compassionate and ethical manner

Ethical practices regarding animal testing

This class focuses on the regulatory approval process for drugs, foods, cosmetics and more.

Proper compliance with regulatory rules

Legal implications in regulatory issues

Ethical considerations when bring a new product to market

The associate degree in biotechnology prepares students to eventually move into the bachelors degree program. Though there are some employers who will accept students who have only the associate degree, many entry-level jobs do require the four-year education. The associate degree requires four years of study to complete, though some accelerated programs might allow completion in as little as 18 months. Some common courses found in the associate in biotech program include:

This course serves as an important overview for those who are interested in the biotech field, including a look at career options.

Use of safe laboratory procedures

Understanding the variety of potential careers and how they relate to each other

Applying the basics of biotech to day-to-day life

Students will learn quality assurance principles and how they relate to the biotech fields.

Understanding the differences in regulated and non-regulated work environments

Quality system usage, including Lean and Six Sigma

Theoretical views of quality assurance as applied to real-world events

Focuses on computational biology and bioinformatics as it relates to processes and end results.

Methods for high-volume data collection

Storing and accessing biological data

Use of common programs and algorithms to analyze data

For most careers in biotechnology including that of biomedical engineer, food scientist, microbiologist, plant and soil scientist, and agricultural engineer, among others a bachelors degree is required for entry-level work. The bachelors degree typically takes four years to complete and offers some opportunities for specialization through the use of electives under the biotechnology umbrella. Some classes that students can expect to take include:

Students explore the current research in biological science and analyze it according to biotechnology principles.

Critical analysis of current research

Use of scientific reasoning to make evaluative decisions

Understanding core biological concepts

Focus on the structure and function of cells, with an emphasis on eukaryotic cell biology.

Use molecular biology knowledge to draw research conclusions

Understand DNA replication and repair

The applications of genetic engineering

An in-depth look at safety procedures and proper management of laboratory spaces.

Management of personnel, space, inventory and equipment

Proper communications with stakeholders

Compliance with all safety and health regulations

The masters in biotechnology degree allows students to enhance their knowledge through a specialized curriculum. The masters in biotech is made up of a few core courses, which are then enhanced by electives that focus on the particular educational path a student wants to carve out for themselves. The masters degree takes two to three years to complete, depending upon the program. Many programs are available online, as schools recognize the need for a flexible schedule for those who are already working in the field.

Some courses that can be found at the masters level include:

Focuses on all the aspects of project management, such as working in teams, managing time, structuring projects and more.

Consideration of each phase of a project

Communicating with a wide variety of people involved in a project

Monitoring and controlling change

Students will learn the ins and outs of federal funding and regulations, writing grant proposals, and other sources of funding for research and development.

Students will study how to apply a comprehensive validation philosophy to new ventures in biotech.

Creating equipment or processes that are less prone to failure

Designing robust yet cost-effective projects

Creating validation documents in line with rules and regulations

The doctorate is the pinnacle of the biotechnology field, and offers students quite broad autonomy when choosing an original research project and focus of study. Those who intend to work with in-depth research or move into teaching will need to earn the PhD. Some professions require it, such as that of animal scientist or biophysicist. The doctoral program usually takes between three and four years to complete, though some schools allow up to eight years for completion of the dissertation. Some courses that might be found at the PhD level include:

Students will explore cutting-edge research areas and instruments, with a rotation that takes them through biomedical and biotechnology areas.

Familiarity with the latest technologies

Refresher on how to use instruments that considered out-of-date but might be advantageous for some projects

How to balance research between different laboratories and get the same results using different systems

Students will examine upper-level biotechnology or bio-engineering problems through the lens of equations and statistics.

High-level mathematics literacy

Advanced numerical methods

Refresher on statistical analysis

Students will engage in discussions with leaders in the field on current events and ethical issues that arise from the use of technology in the biological field.

Proper development of biological products

Conducting ethical biomedical research

Marketing and transparency in presenting new biotechnologies to the public

The U.S. biotech industry grew by just about every measure in 2014, according to Ernst and Youngs 2015 industry report. Revenue was up 29 percent, net income increased 293 percent and there were 164 more biotech companies than during the previous year. All of this meant one thing for jobs: There were a lot more of them. The industry added over 10,000 new jobs in 2014, which equates to a staggering 10 percent annual growth rate. Of course, not all of these jobs were for scientists and researchers many were for support staff one might find in any industry. Jobs specific to biotechnology involving research and development and manufacturing are outlined below.

The Bureau of Labor Statistics (BLS) combines three related careers under the heading of agricultural and food scientist: animal scientist, food scientist and technologist, and soil and plant scientist. Although all have the ultimate task of improving farm productivity, they accomplish this in different ways. Each are discussed separately here.

Many people dont think of farming as being sophisticated. Seeds are planted, crops are watered, and eventually food is harvested. But it is an extraordinarily advanced field, and the largest farms are essentially food factories. Engineers are involved in research and development as well as manufacturing. They might oversee water supply and usage, design comfortable areas for the animals, and create machines that can efficiently harvest crops with minimal food loss. Agricultural engineers spend their time both in offices designing systems and on farms testing and applying those systems.

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Degrees in Biotechnology | How to Have a Biotechnology Career

Regenerative Medicine is; at its core, a conservative therapy. We do not utilize drugs, surgery or foreign materials to treat your painful condition. We use your very own cells to naturally repair and regenerate the affected tissues to reverse the damage. Powerful cells in your bone marrow called Mesenchymal Stem Cells can change and grow into new muscle, tendon, ligament, bone and even cartilage when called upon by the body. Growth factors provided by the platelets in your blood further stimulate and enhance this process. Marrow is harvested from the bone at the back of your waist through a relatively gentle, low volume aspiration.

From a simple blood draw, we can concentrate the platelets in a centrifuge. The combined injectate is skillfully targeted to the area needing treatment using state-of-the-art imaging techniques. In a time when we are flooded with more drugs and supplements than ever offering to treat injury and pain, people are demanding organic remedies and more natural cures. We are extremely proud to add this fantastic therapy to the already comprehensive list of services provided.

Watch below to see Dr. Roth featured in the series Hooked: Opioid Alternative from Fort Waynes NBC news station.

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Summit Regenerative Medicine

Yoav Gilad, PhD

Chief, Section of Genetic Medicine

University of ChicagoDepartment of Medicine

The Section of Genetic Medicine was created over 10 years ago to both build research infrastructure in genetics within the Department of Medicine and to focus translational efforts related to genetics. As a result, the Section of Genetic Medicine is shaping the future of precision medicine with very active and successful research programs focused on the quantitative genetics, systems biology and genomics, and bioinformatics and computational biology. The Section provides extremely valuable collaborations with investigators in the Department of Medicine who are seeking to develop new and more powerful ways to identify genetic risk factors for common, complex disorders with almost immediate clinical application.

The Section of Genetic Medicine continues to shape the future of personalized medicine with successful research programs focused on the quantitative genetic and genomic science. The Section provides extremely valuable collaborations with investigators in the Department of Medicine who are seeking to develop new and more powerful ways to identify genetic risk factors for common, complex disorders with almost immediate clinical application.

The Section of Genetic Medicine conducts impactful investigations focused on quantitative genetics, systems biology and genomics, bioinformatics and computational biology. Some highlights from the past year include:

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Genetic Medicine - University of Chicago - Department of ...

Dr. Pendse's Biography Dr. Pendse provides comprehensive eye care including the medical management of Glaucoma. He specializes in cataract surgery utilizing the most advanced technology including the newest intraocular lens implants that correct astigmatism (AcrySof Toric), and correct both distance and near vision (Crystalens, ReStor, and Tecnis Multifocal). Dr. Pendse also offers Laser Refractive Surgery and Functional Eyelid Surgery. He received his Bachelor of Science degree in Engineering from the University of Pennsylvania. As a graduate of Temple University School of Medicine, he was selected to the Alpha Omega Alpha Medical Honor Society. He completed his ophthalmology residency at the prestigious Wills Eye Hospital where he served as Co-Chief Resident during his final year. After his residency, he was in private practice for three years in Wilmington, Delaware and an additional two years in Philadelphia. He is an experienced surgeon who teaches Cataract Surgery to Resident Physicians training at the Wills Eye Institute. Dr. Pendse is Board Certified and on staff at Aria Health, Thomas Jefferson University Hospital and the Wills Eye Institute. He is actively involved in the education of the Ophthalmology Residents at Wills Eye Institute as a member of the Cataract and Primary Eye Care Service. He also covers Trauma Call at the Wills Eye Emergency Room and performs many emergency eye surgeries there.

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Ophthalmologists near North Plainfield, NJ - Eye Surgeon

Stem cell facts

What are stem cells?

Stem cells are cells that have the potential to develop into many different or specialized cell types. Stem cells can be thought of as primitive, "unspecialized" cells that are able to divide and become specialized cells of the body such as liver cells, muscle cells, blood cells, and other cells with specific functions. Stem cells are referred to as "undifferentiated" cells because they have not yet committed to a developmental path that will form a specific tissue or organ. The process of changing into a specific cell type is known as differentiation. In some areas of the body, stem cells divide regularly to renew and repair the existing tissue. The bone marrow and gastrointestinal tract are examples of areas in which stem cells function to renew and repair tissue.

The best and most readily understood example of a stem cell in humans is that of the fertilized egg, or zygote. A zygote is a single cell that is formed by the union of a sperm and ovum. The sperm and the ovum each carry half of the genetic material required to form a new individual. Once that single cell or zygote starts dividing, it is known as an embryo. One cell becomes two, two become four, four become eight, eight become sixteen, and so on, doubling rapidly until it ultimately grows into an entire sophisticated organism composed of many different kinds of specialized cells. That organism, a person, is an immensely complicated structure consisting of many, many, billions of cells with functions as diverse as those of your eyes, your heart, your immune system, the color of your skin, your brain, etc. All of the specialized cells that make up these body systems are descendants of the original zygote, a stem cell with the potential to ultimately develop into all kinds of body cells. The cells of a zygote are totipotent, meaning that they have the capacity to develop into any type of cell in the body.

The process by which stem cells commit to become differentiated, or specialized, cells is complex and involves the regulation of gene expression. Research is ongoing to further understand the molecular events and controls necessary for stem cells to become specialized cell types.

Stem Cells:One of the human body's master cells, with the ability to grow into any one of the body's more than 200 cell types.

All stem cells are unspecialized (undifferentiated) cells that are characteristically of the same family type (lineage). They retain the ability to divide throughout life and give rise to cells that can become highly specialized and take the place of cells that die or are lost.

Stem cells contribute to the body's ability to renew and repair its tissues. Unlike mature cells, which are permanently committed to their fate, stem cells can both renew themselves as well as create new cells of whatever tissue they belong to (and other tissues).

Why are stem cells important?

Stem cells represent an exciting area in medicine because of their potential to regenerate and repair damaged tissue. Some current therapies, such as bone marrow transplantation, already make use of stem cells and their potential for regeneration of damaged tissues. Other therapies that are under investigation involve transplanting stem cells into a damaged body part and directing them to grow and differentiate into healthy tissue.

Embryonic stem cells

During the early stages of embryonic development the cells remain relatively undifferentiated (immature) and appear to possess the ability to become, or differentiate, into almost any tissue within the body. For example, cells taken from one section of an embryo that might have become part of the eye can be transferred into another section of the embryo and could develop into blood, muscle, nerve, or liver cells.

Cells in the early embryonic stage are totipotent (see above) and can differentiate to become any type of body cell. After about seven days, the zygote forms a structure known as a blastocyst, which contains a mass of cells that eventually become the fetus, as well as trophoblastic tissue that eventually becomes the placenta. If cells are taken from the blastocyst at this stage, they are known as pluripotent, meaning that they have the capacity to become many different types of human cells. Cells at this stage are often referred to as blastocyst embryonic stem cells. When any type of embryonic stem cells is grown in culture in the laboratory, they can divide and grow indefinitely. These cells are then known as embryonic stem cell lines.

Fetal stem cells

The embryo is referred to as a fetus after the eighth week of development. The fetus contains stem cells that are pluripotent and eventually develop into the different body tissues in the fetus.

Adult stem cells

Adult stem cells are present in all humans in small numbers. The adult stem cell is one of the class of cells that we have been able to manipulate quite effectively in the bone marrow transplant arena over the past 30 years. These are stem cells that are largely tissue-specific in their location. Rather than typically giving rise to all of the cells of the body, these cells are capable of giving rise only to a few types of cells that develop into a specific tissue or organ. They are therefore known as multipotent stem cells. Adult stem cells are sometimes referred to as somatic stem cells.

The best characterized example of an adult stem cell is the blood stem cell (the hematopoietic stem cell). When we refer to a bone marrow transplant, a stem cell transplant, or a blood transplant, the cell being transplanted is the hematopoietic stem cell, or blood stem cell. This cell is a very rare cell that is found primarily within the bone marrow of the adult.

One of the exciting discoveries of the last years has been the overturning of a long-held scientific belief that an adult stem cell was a completely committed stem cell. It was previously believed that a hematopoietic, or blood-forming stem cell, could only create other blood cells and could never become another type of stem cell. There is now evidence that some of these apparently committed adult stem cells are able to change direction to become a stem cell in a different organ. For example, there are some models of bone marrow transplantation in rats with damaged livers in which the liver partially re-grows with cells that are derived from transplanted bone marrow. Similar studies can be done showing that many different cell types can be derived from each other. It appears that heart cells can be grown from bone marrow stem cells, that bone marrow cells can be grown from stem cells derived from muscle, and that brain stem cells can turn into many types of cells.

Peripheral blood stem cells

Most blood stem cells are present in the bone marrow, but a few are present in the bloodstream. This means that these so-called peripheral blood stem cells (PBSCs) can be isolated from a drawn blood sample. The blood stem cell is capable of giving rise to a very large number of very different cells that make up the blood and immune system, including red blood cells, platelets, granulocytes, and lymphocytes.

All of these very different cells with very different functions are derived from a common, ancestral, committed blood-forming (hematopoietic), stem cell.

Umbilical cord stem cells

Blood from the umbilical cord contains some stem cells that are genetically identical to the newborn. Like adult stem cells, these are multipotent stem cells that are able to differentiate into certain, but not all, cell types. For this reason, umbilical cord blood is often banked, or stored, for possible future use should the individual require stem cell therapy.

Induced pluripotent stem cells

Induced pluripotent stem cells (iPSCs) were first created from human cells in 2007. These are adult cells that have been genetically converted to an embryonic stem celllike state. In animal studies, iPSCs have been shown to possess characteristics of pluripotent stem cells. Human iPSCs can differentiate and become multiple different fetal cell types. iPSCs are valuable aids in the study of disease development and drug treatment, and they may have future uses in transplantation medicine. Further research is needed regarding the development and use of these cells.

Why is there controversy surrounding the use of stem cells?

Embryonic stem cells and embryonic stem cell lines have received much public attention concerning the ethics of their use or non-use. Clearly, there is hope that a large number of treatment advances could occur as a result of growing and differentiating these embryonic stem cells in the laboratory. It is equally clear that each embryonic stem cell line has been derived from a human embryo created through in-vitro fertilization (IVF) or through cloning technologies, with all the attendant ethical, religious, and philosophical problems, depending upon one's perspective.

What are some stem cell therapies that are currently available?

Routine use of stem cells in therapy has been limited to blood-forming stem cells (hematopoietic stem cells) derived from bone marrow, peripheral blood, or umbilical cord blood. Bone marrow transplantation is the most familiar form of stem cell therapy and the only instance of stem cell therapy in common use. It is used to treat cancers of the blood cells (leukemias) and other disorders of the blood and bone marrow.

In bone marrow transplantation, the patient's existing white blood cells and bone marrow are destroyed using chemotherapy and radiation therapy. Then, a sample of bone marrow (containing stem cells) from a healthy, immunologically matched donor is injected into the patient. The transplanted stem cells populate the recipient's bone marrow and begin producing new, healthy blood cells.

Umbilical cord blood stem cells and peripheral blood stem cells can also be used instead of bone marrow samples to repopulate the bone marrow in the process of bone marrow transplantation.

In 2009, the California-based company Geron received clearance from the U. S. Food and Drug Administration (FDA) to begin the first human clinical trial of cells derived from human embryonic stem cells in the treatment of patients with acute spinal cord injury.

What are experimental treatments using stem cells and possible future directions for stem cell therapy?

Stem cell therapy is an exciting and active field of biomedical research. Scientists and physicians are investigating the use of stem cells in therapies to treat a wide variety of diseases and injuries. For a stem cell therapy to be successful, a number of factors must be considered. The appropriate type of stem cell must be chosen, and the stem cells must be matched to the recipient so that they are not destroyed by the recipient's immune system. It is also critical to develop a system for effective delivery of the stem cells to the desired location in the body. Finally, devising methods to "switch on" and control the differentiation of stem cells and ensure that they develop into the desired tissue type is critical for the success of any stem cell therapy.

Researchers are currently examining the use of stem cells to regenerate damaged or diseased tissue in many conditions, including those listed below.

References

REFERENCE:

"Stem Cell Information." National Institutes of Health.

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Stem Cells - MedicineNet

Its important for people suffering from kidney disease to know theyre not alone. Heres a list of todays celebrities and athletes who have suffered from kidney disease.

Peter Burns, singer for the band, Dead or Alive, acute kidney failure caused by several kidney stones

Nick Cannon, singer, actor, suffers from lupus nephritis

Grizzwald Chapman, actor in 30 Rock, kidney failure due to hypertension, transplant recipient

Natalie Cole, singer, kidney failure after treatment for hepatitis C, transplant recipient

Lucy Davis, actress in The Office, kidney failure due to diabetes, transplant recipient

Aron Eisenberg, actor in Star Trek: Deep Space Nine, born with one partially functioning kidney, transplant recipient

Sean Elliott, basketball player, suffered from FSGS, transplant recipient

Freeway, rap musician, kidney failure due to diabetes, waiting for a kidney transplant

Stephen Furst, actor, diabetic, transplant recipient

Jennifer Harman, professional poker player, hereditary kidney disease, two-time transplant recipient

Ed Hearn, baseball player, suffered from FSGS, three-time transplant recipient

Ken Howard, actor in 30 Rock, kidney failure caused by a misdiagnosed blockage, transplant recipient

Paul Hutchins, football player, FSGS, received double kidney transplant

Sarah Hyland, actress, suffered from kidney dysplasia, received a kidney from her father

Donald Jones, football player, IgA nephropathy, received a kidney from his father and is playing baseball post-transplant

Chris Kemoeatu, football player, hereditary kidney disease, received a kidney from his brother, also a football player

Jonah Lomu, New Zealand rugby player, kidney failure due to nephrotic syndrome, sadly passed away in November 2015 while waiting for another kidney transplant

George Lopez, comedian, hereditary kidney disease, transplant recipient

Scott MacIntyre, American Idol singer, family history of kidney disease, transplant recipient, now in need of another kidney transplant

Aries Merritt, Olympic hurdler, rare congenital kidney disease, transplant recipient

Tracy Morgan, actor in 30 Rock, kidney failure due to diabetes, transplant recipient

Alonzo Mourning, basketball player, suffered from FSGS, transplant recipient

Jeremy Newberry, football player, kidney disease caused by painkillers

Liam Payne, singer for the band, One Direction, born with partially functioning kidney

Pele, soccer legend, had a kidney removed in the 1970s, recently underwent surgery for kidney stones

Phillip Phillips, singer, chronic kidney stones

Amy Purdy, athlete and actress, kidneys failed two years after hospitalization for septic shock, received a kidney from her father

Jon Rankin, Olympic athlete, FSGS

Bobby Rydell, singer,kidney failure caused by liver disease, transplant recipient

Neil Simon, playwright, suffered from PKD, transplant recipient

Clyde Simms, pro soccer player, FSGS

Dayna Stephens, jazz musician, diagnosed with FSGS, in need of kidney transplant

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Regenerative medicine technologies are relatively new forms of treatment designed to enhance your bodys ability to heal itself. These treatments use natural substances that modify your natural healing mechanisms to help joints, tendons and ligaments heal and repair themselves.

There are three branches of regenerative medicine: Rejuvenation, Replacements, and Regeneration.

There are 3 types of regenerative medicine offered at our centers, including:

PRP is a mixture of growth factors and other proteins found in the platelets of your own blood. These platelets migrate to areas of injury in the body and initiate and enhance a healing response. PRP treatments utilize a technology where we draw your own blood, concentrate the platelets and growth factors, and inject them back into the body at sites of injury or degeneration. These proteins enhance the activity of the healing mechanisms and decrease the mediators of inflammation to help make a patient feel better and heal the injury.Download more information

Cell-based therapy is a mixture of growth factors, proteins and mesenchymal stem cells that are found naturally in the body. These substances can be harvested from either your fat or bone marrow and injected into areas of injury or degeneration to enhance healing and ongoing repair. These mesenchymal stem cells have the ability to differentiate into other types of cells and continue to help your healing over the long term. Download more information

Amniotic products use either fluid or tissue to protect, cushion and reduce inflammation in joints and tendons. Amniotic tissue contains bioactive proteins harvested from healthy voluntary donors and therefore allows this procedure to be minimally invasive. Download more information

I am a 52-year-old physician and CrossFit athlete. Dr. Arthur Valadie surgically repaired my left knee 12 years ago. The outcome was excellent. Recently, he injected stem cells in the same knee. My knee feels fantastic and there is no exercise I cant perform!

After two years of shoulder pain, Dr. Valadie offered the Lipogems stem cell therapy as an alternative to conventional rotator cuff surgery. I am now 90+ days removed from the procedure and honestly amazed with the result. Im 80% back to my pre-injury condition. I cannot recommend Dr. Valadie, his team and this procedure highly enough. Simply incredible. Thank you!

I have suffered with osteoarthritis for three years in my right knee. After having the stem cell replacement procedure in November 2017, I have less pain and inflammation in the knee. I have much more ease with daily activities and continue to see improvement. The procedure was simple and painless. There was some discomfort after, but only within the first 24 hours.

PRP treatments are most effective for chronic ligament and tendon sprains and strains, that have failed other forms of treatments. Some of the treatments that can benefit from PRP include:

In addition to the list above PRP can also be effective in osteoarthritis cases, by stimulating the healing process of the cartilage, which reduces the pain. The areas that can benefit from PRP include:

First, a small amount of blood is drawn from the patient. Preparation of the solutions can take 25-30 minutes. Once the blood is drawn, it is placed in a machine called a centrifuge, that spins the blood at a high speed. This machine helps separate the blood into red blood cells and concentrated platelets. Once the blood is separated from the platelets, the blood is discarded and what remains is a concentrated platelet-rich plasma, known as PRP.

A stem cell is a cell with the unique ability to develop into specialized cell types in the body. They may be used to help your body heal tissues that have been damaged due to injury or degeneration.

These cells can be harvested from adipose tissue (body fat) or bone marrow with a relatively minor procedure. This is done under local anesthetic to minimize the pain of harvesting. Discomfort from the harvest is usually relatively mild.

Mesenchymal stem cell injections help the body heal itself. The cells can turn into cell types appropriate for the body part which can then help aid in the healing process. These injections are significantly less invasive than surgery and can shorten recovery time and diminish the risks compared to traditional treatments.

There are four types of Cell-Based Therapy that use the latest biological drugs with anti-inflammation agents and steroids, used for inflammatory bowel disease (IBD). The goal for these four therapies is to cure IBD, cell-based therapies offer hope to patients when traditional treatments have failed.

This type of injection is a minimally-manipulated injectable allograft designed to reduce inflammation as well as to protect, cushion, and lubricate joints and tendons.

While a baby is in the womb, it is situated within the amniotic sac. Inside the sac, the baby is surrounded by amniotic fluid. Amniotic fluid is gathered by a relatively easy, minimally invasive procedure from a willing donor, that is neither harmful to the mother or baby.

These injections can counteract inflammation and the harmful proteins that can cause joint pain. This diminished inflammation as well as lubrication can decrease pain and improve function.

We are in the pioneering days of regenerative medicine. Compared to other traditional medical treatments, regenerative medicine treatments have fewer clinical studies because of the relatively recent development of these technologies. We use and follow all available clinical studies regarding these treatments, so we can provide evidence-based ethical regenerative medicine treatments. These treatments are provided by board-certified, fellowship-trained orthopedic surgeons and spine/pain management physicians.

No, insurance does not cover regenerative medicine treatments as it is a relatively new field of medicine. Fortunately, there are many pricing options depending on the treatment you choose.

These are non-surgical treatments. Depending on the mode of treatment, tissue can be obtained either from a healthy donor, a simple blood draw, or a slightly more invasive procedure to obtain mesenchymal stem cells depending on the treatment you choose.

While the complete healing process can take several months, the downtime after the procedure is extremely minimal compared to that of surgery recovery.

If you want to learn more about regenerative medicine, please dont hesitate to contact us. At Coastal Orthopedics, we offer same-day appointments at three locations across Bradenton, Florida to serve you better.

Contact Our Regenerative Medicine Concierge TodayCall Coastal Orthopedics at941-794-5868

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Regenerative therapiesfor the spine are the future for spinal treatments. We are excited to offer innovative techniques as new and improved ways to try to heal spinal problems without having to undergo surgery. Regenerative therapy options hold wonderful healing potential and represent the future of modern medicine. We are excited to offer innovative techniques as new and improved ways to try to heal spinal problems without having to undergo surgery.

In the United States alone, more than 400,000 lumbar discectomies and 500,000 spinal fusions are performed each year for symptoms related to lumbar disc degeneration. The ability to get these to heal without surgery has been a long-term goal of many patients and physicians alike.

At Virginia Spine Institute, we are working to promote healing without surgery. Virginia Spine Institute continues to be on the forefront of treatment options and is proud to offerstem cell therapy treatmentsfor patients as part of ourcomprehensivenon-operative treatmentoptions.

Painful discs in the neck or low back are common causes of severe back pain and disability. Historically, therapies did not exist to regenerate the degenerative process in a vertebral disc, often leaving surgical intervention as the only option if other non-operative treatment options have failed. In selected patients, we now have hopes of better ways to treat spinal disease.

Learn if you are a candidate for this treatment.

Click to Schedule Your Initial Consultation

We obtain a patients own stem cells by aspirating tissue from the patient's hip bone or from their fat cells. These cells are centrifuged down to identify and separate specific primitive cells that will help heal tissues. Stem cells are theninjected into the disc, stimulating healing of the disc by using these primitive blood cells to stimulate regeneration of the collagen within the disc. We are excited to report improvements in our patients treated with stem cells.

Stem cells are undifferentiated cells that have the potential to become specialized types of cells. Stem cells can be categorized as embryonic stem cells or adult stem cells.Embryonic stem cells are derived from a human fetus; there are many ethical concerns with embryonic stem cells, and these are not used in our practice.

Adult stem cells are derived from adults, sometimes obtained from your very own body! Adult stem cells are further divided into different categories. For example, the types of adult stem cells we use to treat musculoskeletal issues are known as mesenchymal stem cells (MSCs). These are multi-potent cells that can differentiate into bone cells, cartilage cells, or fat cells. Its important to note that they cannot differentiate into any other type of cell.

The human body has multiple storage sites for stem cells to repair degenerated and injured structures. We have found that obtaining stem cells from the hip bone (iliac bone) is easily performed within minutes and, in most cases, is a fairly painless procedure for the patient. The stem cells are obtained from your own bone marrow; just minutes later, they are used for treatment.

This procedure is done in our office and starts with the patient lying face down on the examination table. The skin is first numbed with a novocaine solution. After that, the cortex of the hip bone (iliac bone) is numbed. Next, under x-ray (fluoroscopic) guidance, a special needle is advanced through the bone to the cortex of your hip bone into the bone marrow. The liquid marrow - which contains the stem cells - is then withdrawn into a syringe. Finally, the needle is removed, and a small bandage is placed where the needle was inserted.

After the procedure, the syringe of stem cells is taken to the lab and placed in a specialized machine called a centrifuge. The centrifuge spins the bone marrow solution and stem cells are separated from the non-useful cells. The concentrated stem cells are then transferred to a new syringe. Now, the stem cells are ready for the treatment.

Not all patients will be a candidate for these disc regeneration procedures. For those whom are ideal candidates, this provides great hope with reduction in pain and improved quality of life without the need for major surgery. We are excited about these great advances in health care and look forward to helping you live pain free.

Stem cell injections are most commonly used for treatment of the following conditions:

The area of injury is first identified using ultrasound or fluoroscopy. The area is then sterilized, and the skin above the area is numbed with a novocaine-type solution. Using ultrasound or fluoroscopic guidance, the needle is guided to the area of injury, and the stem cell solution is injected. All the regenerative injections performed at our practice are performed under image guidance with ultrasound or fluoroscopy to confirm accurate placement of the stem cells.

The risks depend on the area being treated; however, there is always a potential risk of an injection causing infection, bleeding, or nerve damage. It is important to note that there is no risk of allergic reaction since you are using your own stem cells. At Virginia Spine Institute we always recommended the safest and most efficient procedures for our patients, however, your physician will review any possible risks associated with this treatment prior to administering.

The benefit is usually seen approximately two to three months after the whole treatment protocol has completed; however, you may start to notice the benefit sooner than this.

In most cases, patients respond very well to just one treatment; however, the patient may require two to three injections. We never perform more than three injections within a span of 12 months.

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Originally posted here:
Regenerative Stem Cell Therapy | Treatment for Back Pain | VSI

Risks and Benefits of Stem Cell Therapy for Knees

We are already aware of the several risks associated with knee replacement surgery. Theyre big and scary. When you choose stem cell therapy as an alternative for knee replacement, however, most of those risks evaporate. The biggest risk youll face is the risk of infection, but that is extremely rare because the procedure is so minimally invasive.

The benefits of stem cell treatment for knees, on the other hand, are huge. Check it out:

The procedure is relatively quick, especially compared to surgery. We have our equipment and labs in-house, and the outpatient procedure can be done in a single day (a few hours, to be more precise).

The costs involved are reasonable. Your initial consultation, exam, and treatment planning are all done for at a low cost to help reduce your treatment expenses.

Stem cell therapy for knees is natural. We do not produce synthetic stem cells. We dont even use donor cells from embryos or other adults. Instead, we use your own stem cells. We literally take your stem cells from one part of your body and inject them into your knees or other problem areas. And the entire treatment is done in one sitting. It is as natural as you can get!

Recovery time is minimal. With surgery, the recovery time can last for months, many of which you spend immobile or with your mobility severely limited. With stem cell knee injections, this is not the case. You walk in and walk out of the procedure on your own, and your daily routine should stay the same. In a few weeks, you begin to increase your activity levels and do more!

Read more here:
Stem Cell Therapy for Knees vs Surgery - Which Works Best?

One of the great hopes for stem cell regeneration therapy is the potential to grow healthy organs from scratch. In late 2014, MedPage Today reported that researchers in New York City had induced human embryonic stem cells into thyroid cells, and are exploring the possibility of creating a like-new thyroid gland in patients who have had their thyroid surgically removed. The research was announced at the 2014 annual American Thyroid Association meeting.

According to R. Michael Tuttle, MD of Memorial Sloan Kettering Cancer Center in New York City, co-chair of the ATA scientific program: "It would be wonderful to be able to regrow a normal thyroid." As part of this research, Terry Davies, MD, and his colleagues at Mount Sinai Hospital in New York City are investigating new strategies for inducing embryonic stem cells into thyroid cells.

While a tissue-engineered thyroid transplant may happen eventually, we are not at a point yet where patients are in a position stem cell-generated thyroid glands. But doctors are making regenerative medical strides today, treating some thyroid and endocrine patients with a different kind of stem cell: adult stem cells, aka autologous mesenchymal cells. These stem cells are derived from the patient's own adipose (fatty) tissue, and carry none of the ethical issues and controversies surrounding human embryonic stem cells.

Using technology pioneered by the Cell Surgical Network, a number of physicians are performing investigational applications of adult stem cell regenerative therapy in protocols described as "patient-funded testing." In this patient-funded protocol, patients - who are made fully aware of the investigational nature and the status of this type of procedure with the FDA -- can apply to be part of investigational review studies exploring the effects the treatment on several autoimmune diseases, including optic neuritis, rheumatoid arthritis, multiple sclerosis, and Hashimoto's thyroiditis, and other conditions, including various orthopedic issues, peripheral neuropathy, Parkinson's disease, asthma , and other diseases and conditions.

Here's an overview of how the medical procedure works. A mini-liposuction yields what is known as "stromal vascular fraction" or SVF. The SVF is composed of millions of adult stem cells, as well as other growth factors. After a filtration process, the SVF is re-injected into the patient it is harvested from. Such autologous stem cell transplants in which donor and recipient are the same patient eliminate chance of rejection, and are already showing promise in patients with various thyroid and endocrine disorders.

Judy Richardson, 56, of Wabash, Indiana, has struggled with Hashimoto's thyroiditis for a number of years. She learned of SVF treatment through research online, and sought out the physician in her area who offered the treatment. The doctor she found in her area is not an endocrinologist; he's a plastic surgeon, with years of practice performing liposuctions. Dr. Robert Jackson of Hamilton Surgical Arts in Noblesville, Indiana-- an affiliate of the Cell Surgical Network -- treated Richardson with her own fat-derived stem cells twice in 2013, injecting her harvested cells intravenously both times.

"After the first IV injection, I felt so much better," Richardson recalls. "I didn't get a cold for a year." Previously, she explains, "I was at the doctor every month getting antibiotic shots. I felt so bad I just wanted to die. My bones were so weak, I would wake up at night crying I couldn't bear my own weight on my bones. My elbow popped out of its socket. My doctors thought I had bone cancer. It was terrible. I gave up on life."

Richardson says she continues to feel improvements since her second IV injection of SVF, and her endocrinologist -- Dr. Ashok Kadambi of Fort Wayne Endocrinology in Fort Wayne, Indiana -- has said he is thrilled with her progress post-SVF treatment. Dr. Kadambi was so impressed with Richardson's progress that he is considering becoming an affiliate of the Cell Surgical Network himself.

Richardson also suffers from Addison's disease, an endocrine condition that is more common in patients with Hashimoto's thyroiditis. "My adrenals had pretty much quit functioning," she says. "I was on steroids, at a dosage of 20 milligrams per day."

Today, since her second SVF treatment, Richardson says, "I'm doing well enough that my endocrinologist is weaning me off of the steroids I'm down to 4 milligrams per day." As for her thyroid replacement medications, says Richardson: "I was on 120 milligrams per day, but they've been lowering it consistently I'm now down to 75 milligrams."

During his training and accreditation at the California Stem Cell Treatment Center, and before becoming an affiliate of the Cell Surgical Network in 2012, Dr. Schrader himself underwent stem cell therapy to ease chronic pain in his shoulders and his torn right meniscus.

Meanwhile Davis, his eldest son, was diagnosed with various health problems while still in high school. According to Dr. Schrader: "He's a really great athlete, a star football player, but it seemed like he might have had asthma or a heart problem. He was always out of breath, and seemed to have lost his endurance. We had him checked out, and his thyroid was low plus he tested positive for Hashimoto's. So his doctor put him on Armour thyroid."

The following year, when Davis went off to college, his father recalls: "It seemed like he was struggling with sleep and concentration, and just feeling sluggish and run-down. We had to pull him out of semester because he just wasn't making it medically."

At that point, Schrader decided to try stem cell therapy on his son. Impressed by the medical literature he'd studied about the immunomodulatory property of adult stem cells, Schrader gave his son an IV transplant of SVF. Today, the proud dad reports, "He's probably 80-90 percent better. He went back to school and ended the semester with a B average!"

This treatment is considered investigational. You can read more about the status of the treatment with the FDA here.

Not every thyroid or endocrine patient -- or those with other conditions being treated with SVF - is a good candidate for this treatment. And at this point, given that it is an investigational treatment, insurance usually does not cover the costs, which is why the treatment is typically patient-funded.

But for those interested in exploring this cutting-edge treatment, a good first step is to contact one of the physicians who is a member of the Cell Surgical Network and who is familiar with the SVF/stem cell therapy. For a detailed and compelling account of a successful autologous stem cell transplant, which cured author Julia Szabo's chronic inflammatory bowel disease -- as well as her dog's osteoarthritis -- I recommend reading her book: Medicine Dog: The Miraculous Cure That Healed My Best Friend And Saved My Life .

View original post here:
Stem Cell Therapy for Thyroid Issues: A New Frontier

The chronic disease Osteoarthritis (OA) is characterized by the breakdown of cartilage. As the cartilage in joints of the body deteriorate, bones begin to rub against one another. This can cause pain and stiffness that make joint movement difficult. OA can also result in damage to ligaments, menisci and muscles. There are two types of OA primary and secondary. Primary osteoarthritis is generally associated with the aging process and is simply the wears and tears one endures throughout life. As you become older, the more likely you are to have some degree of primary osteoarthritis; however, this does not mean OA must be a normal aspect of aging. Secondary osteoarthritis tends to develop relatively early in life, typically 10 or more years after a specific cause, such as an injury.

Osteoarthritis most often occurs in knees, hips, and hands. Other joints, like the shoulders, can also be affected. OA rarely affects other joints but can as a result of injury or struggles with obesity. The pain and stiffness of osteoarthritis can make it difficult to do daily activities and exercises. In the early stages of OA, damage begins to affect the cartilage that covers the joint surfaces of the body and is limited to a small area. OA is considered a progressive disease where over time, bone density surrounding the joint increases solidifying a diagnosis. In the late stages of OA, the joint cartilage in the affected area is not only diseased and damaged, but completely worn away. Without that protective plush covering, adjoining bones rub directly against each other causing severe pain, swelling, and stiffness.

Osteoarthritis treatments today focus mainly to relieve symptoms. There is currently no cure for OA but many treatments and therapies are available to maintain joint movement, control pain, and relieve stiffness. Medications such as acetaminophen,non-steroidal anti-inflammatory drugs, and narcotics are commonly used to relieve a variety of symptoms. Topical pain relievers are also often prescribed to fight discomfort of diseased joints. Surgery, including joint replacement, may be a considered option for severely damaged joints. Assistive devices, physical therapy, occupational therapy, weight loss, nutritional supplements, and meditation are other approaches offered to help manage the symptoms of osteoarthritis.

Stem cell treatment for Osteoarthritis is a new alternative way to help manage the symptoms of this chronic disease. Stemedix uses adipose, bone marrow aspirate or umbilical cord derived stem cells as methods of therapy for you in your journey to wellness. These regenerative therapies help the bodys natural healing process work faster and more effectively.Recent research in the advancement of stem cell therapy has shown that restoration of these damaged cells through this treatment is possible. The undifferentiated cells heal the body by replacing ones plagued with disease, regenerating new cells, and suppressing the immune systems macrophage response which engulfs and digests the dying cells. Results of several early clinical studies of stem cell treatment for Osteoarthritis have shown promising results. This breakthrough in regenerative medicine shines a light of hope on those battling this degenerative disease. Improvements have been seen in the following symptoms after treatment:

While there is currently no cure for osteoarthritis, our methods can assist in gaining beneficial results that have shown to improve the life and health of those looking to manage their condition and varied symptoms. By using stem cell therapy, an alternative is available for those who have not responded to typical drug treatment or traditional procedures showing less than optimal results. With Stemedix stem cell therapy, your journey to the rebuilding process can begin.

Contact ustoday and let Stemedix provide a worry-free experience accompanied by one of our Care Coordinators to ensure you have the best experience possible.

Read more here:
Stem Cell Treatment For Osteoarthritis | Stemedix

Cord Blood & Regenerative Medicine

The therapeutic potential of cord blood continues to grow.

Regenerative medicine is the science of living cells being used to potentially regenerate or facilitate the repair of cells damaged by disease, genetics, injury or simply aging by stimulating the body's own repair mechanisms.

Why cord blood?

Think about it: the natural power and purity of your newborn's cord blood are responsible for healthy development during pregnancy. So it makes sense that they are the ones most likely to be called upon when studying ways in which science can help restore health.

Cord blood is being used in clinical trials for autism and cerebral palsy.

Over the last few years, cord blood applications have expanded beyond transplant medicine into areas of regenerative medicine in clinical research trials for autism and brain injuries.

After demonstrating that it's safe for children with Autism Spectrum Disorder (ASD) to receive cord blood, a clinical trial is now underway to determine the effects of using a child's own cord blood or unrelated donor cord blood in children with autism. ViaCord families are participating in this innovative research to help kids with conditions once thought untreatable.

Learn more about cord blood and autism

A clinical trial at Duke University recently showed that an infusion of a child's own cord blood appears to improve brain connectivity and motor function in children with cerebral palsy. Twenty ViaCord families participated in this exciting research. Results were published in Stem Cell Translational Medicine. A third study is now underway to determine the safety of using a sibling's cord blood.

Learn more about cord blood and cerebral palsy

Brain Injury:Stroke 68 andHypoxic-IschemicEncephalopathy (HI) 108

Cardiac: Hypoplastic Left Heart Syndrome (HLHS)119

Hearing:Acquired Hearing Loss118

Autoimmune Deficiencies:Type 1 Diabetes84

Read more here:
Cord Blood and Regenerative Medicine | ViaCord

Gene therapy is a cancer treatment that is still in the early stages of research.

Genes are coded messages that tell cells how to make proteins. Proteins are the molecules that control the way cells behave. Our genes decide what we look like and how our body works.We have many thousands of separate genes.

Genes are made ofDNAand they are in the nucleus of the cell. The nucleus is the cell's control centre.Genes are grouped together to make chromosomes. We inherit half our chromosomes from our mother and half from our father.

Cancer cells are different from normal cells. They have changes (called faults or mutations) in several of their genes which make them divide too often and form a tumour. The genes that are damaged mightbe:

Many gene changes thatmake a cell become cancerous are caused by environmental or lifestyle factors. A small numberof people haveinherited faulty genes that increase their risk of particular types of cancer.

Gene therapy is a type of treatment which uses genes to treat illnesses. Researchers have been developing differenttypes of gene therapyto treat cancer.

The ideas for these new treatments have come about because we are beginning to understand how cancer cells are different from normal cells. It is stillearly days for this type of treatment. Some of these treatments are being looked at in clinical trials. Otherscan now be used for some people with types of cancer such as melanoma skin cancer.

Getting genes into cancer cells is one of the most difficult aspects of gene therapy. Researchers are working on finding new and better ways of doing this. The gene is usually taken into the cancer cell by a carrier called a vector.

The most common types of carrier used in gene therapy are viruses because they can enter cells and deliver genetic material. The viruses have been changed so that they cannot cause serious disease but they may still cause mild, flu-like symptoms.

Some viruses have been changed in the laboratory so that they target cancer cells and not healthy cells. So they only carry the gene into cancer cells.

Researchers are testing other types of carrier such as inactivated bacteria.

Researchers are looking at different ways of using gene therapy:

Some types of gene therapy aim to boost the body's natural ability to attack cancer cells. Ourimmune systemhas cells that recognise and kill harmful things that can cause disease, such as cancer cells.

There are many different types of immune cell. Some of them produce proteins that encourage other immune cells to destroy cancer cells. Some types of therapy add genes to a patient's immune cells. Thismakes them better at finding or destroying particular types of cancer.

There are a few trials using this type of gene therapy in the UK.

Some gene therapies put genes into cancer cells to make the cells more sensitive to particular treatments. The aim is to make treatments,such as chemotherapy or radiotherapy, work better.

Some types of gene therapy deliver genes into the cancer cells that allow the cells to change drugs from an inactive form to an active form. The inactive form of the drug is called a pro drug.

First of all you have treatment with thecarrier containing the gene, then you havethe pro drug.The pro drug circulates in the body and doesn't harm normal cells. But when it reaches the cancer cells, it is activated by the gene and the drug kills the cancer cells.

Some gene therapies block processes that cancer cells use to survive. For example, most cells in the body are programmed to die if their DNA is damaged beyond repair. This is called programmed cell death or apoptosis. Cancer cells block this process so they don't die even when they are supposed to.

Some gene therapy strategies aim to reverse this blockage. Researchers are looking at whetherthese new types of treatment will make the cancer cells die.

Some viruses infect and kill cells. Researchers are working on ways to change these viruses so they only target and kill cancer cells, leaving healthy cells alone.

This sort of treatment uses the viruses to kill cancer cells directly rather than to deliver genes. So it is not cancer gene therapy in the true sense of the word. But doctors sometimes refer to it as gene therapy.

An example is a drug called T-VEC (talimogene laherparepvec), also known as Imlygic. It uses a strain of the cold sore virus (herpes simplex virus) that has been changed by altering the genes that tell the virus how to behave. It tells the virus to destroy the cancer cells and ignore the healthy cells.

T-VEC is now available as a treatment for melanoma skin cancer. It can be used to treat some people with melanomawhose cancer cannot be removed with surgery. It is also being looked at in trials for head and neck cancer. You have T-VEC as an injection directly into the melanoma or head and neck cancer.

Use the tabs along the top to look at recruiting, closed and results.

Follow this link:
Gene therapy | Cancer in general | Cancer Research UK

Integrative Doctor Summary: An Integrative Doctor combines the latest advancements of conventional medicine with complimentary alternative approaches to promote wellness of the body, mind, heart, and spirit. An Integrative Doctor focuses on a more holistic approach to relieve pain, reduce stress, find alternatives to prescription medicines, or simply improve an individual's quality of life. An Integrative Doctor will typically offer individualized treatment plans based on a patients' needs. Some of the therapies an Integrative Doctor may incorporate throughout treatment include nutritional supplements, acupuncture, naturopathic medicine, clinical nutrition, massage, and energy healing. Integrative Doctors treat a wide array of ailments and illnesses and offer integrative, holistic care that is designed to treat the person, not just the disease.

Integrative Doctor FAQs: What is an Integrative Doctor?An Integrative Doctor is a doctor who combines conventional medicine with alternative medicine.

What is Conventional Medicine?Conventional Medicine is the system that physicians use to treat diseases. It is one of the practices of an Integrative Doctor.

What is Alternative Medicine?Examples of Alternative Medicine are acupuncture, massage, herbal remedies and supplements. It is also one of the practices of an Integrative Doctor.

How do I find an Integrative Doctor in my city and state?The Wellness.com directory will help you locate an Integrative Doctor in your state. Select Integrative Doctor from the professionals menu and select the state that you are looking to locate an Integrative Doctor in. After you have located your state, find the city that you will need an Integrative Doctor in. Select the state and city and you will see a list of Integrative Doctors in your city and state.

Integrative Doctor Related Terms: holistic, wellness, integrative doctor, alternative medicine, conventional medicine, herbal remedies

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Integrative Doctor in Plainfield, IL - wellness.com

List of Genetics & Molecular Biology Conferences 5th World Congress on Synthetic Biology and Advanced Biomaterials September 19-20, 2018 Tokyo, Japan2nd Annual summit on Cell Metabolism and Cytopathology September 19 - 20, 2018 Philadelphia, USA2nd Annual summit on Cell Signaling and Cancer Therapy September 19 - 20, 2018 Philadelphia, USA5th International Conference on Human Genetics and Genetic Diseases September 21-22, 2018 Philadelphia, USA11th International Conference on Genomics and Pharmacogenomics September 21-22, 2018 Philadelphia, USA10th Annual Conference on Stem Cell and Regenerative Medicine October 08-09, 2018 Zurich, Switzerland21st European Biotechnology Congress October 11-12, 2018 Moscow, Russia11th Annual Conference on Stem Cell and Regenerative Medicine October 15-16, 2018 Helsinki, FinlandAnnual Congress on Cellular Therapies, Cancer, Stem Cells and Bio Medical Engineering October 17-18, 2018 New York, USA11th International Conference on Tissue Engineering & Regenerative Medicine October 18-20, 2018 Rome, Italy4th International Conference on Synthetic Biology and Tissue Engineering October 18-19, 2018 Rome, ItalyAnnual congress on CRISPR-Cas9 Technology and Genetic Engineering October 24-25, 2018 Boston, USA24th Biotechnology Congress: Research & Innovations October 24-25, 2018 Boston, USA2nd Annual Summit on Cell Therapy, Tissue Science and Regenerative Medicine November 9-10, 2018 Atlanta, USA2nd Annual Summit on Stem Cell Research, Cell and Gene Therapy November 9-10, 2018 Atlanta, USA12th International Conference & Exhibition on Tissue Preservation, Life care and Biobanking (B2B & Networking) November 9-10, 2018 Philadelphia, USA9th International conference on Tissue Science and Regenerative Medicine November 12-13, 2018 Singapore City, Singapore4th International Conference on Advances in Biotechnology and Bioscience November 15-17, 2018 Berlin, Germany5th World Congress on Epigenetics and Chromosome November 15-16, 2018 Istanbul, Turkey22nd World Congress on Biotechnology November 19-20, 2018 Bangkok, ThailandInternational Epigenetics and Epitranscriptomics Conference November 26-27, 2018 Helsinki, Finland8th International Conference on Cell & Gene Therapy November 27-28, 2018 Athens, Greece3rd World Biotechnology Congress Dec 03-04, 2018 Sao Paulo, BrazilInternational Conference on Biotechnology and Health Care December 06-07, 2018 Hanoi, Japan11th World Congress on Cell Science, Stem Cell Research & Regenerative Medicine December 07-08, 2018 Chicago, USA13th Annual Conference on Stem Cell & Regenerative Medicine March 07-09, 2019 Nice, France12th World Congress on Cell & Tissue Science March 11-12, 2019 Singapore City, Singapore14th International Conference on Metabolomics and Enzymology March 18-19, 2019 New York, USA2nd World Congress on Cell and Structural Biology March 20-21, 2019 Sydney, Australia9th International Conference and Exhibition on Advanced Cell and Gene Therapy March 21-22, 2019 Rome, Italy11th World Congress and Expo on Cell & Stem Cell Research March 25-26, 2019 Orlando, USA6th World Congress on Human Genetics and Genetic Diseases April 08-10, 2019 Abu Dhabi, UAE9th World Congress on Plant Genomics and Plant Sciences April 11-12, 2019 Wellington, Newzealand7th International Conference on Integrative Biology April 15-16, 2019 Berlin, Germany12th International Conference on Genomics and Molecular Biology April 15-17, 2019 Berlin, GermanyInternational Conference on Cord Blood Banking and Stem cell April 22-23, 2019 Vancouver, Canada12th World Conference on Human Genomics and Genomic Medicine April 22-23, 2019 Abu Dhabi, UAE14th International Conference on Tissue Science , Engineering & Regenerative Medicine April 24-25, 2019 Vancouver, Canada14th International Conference on Tissue Engineering & Regenerative Medicine April 29-30, 2019 Amsterdam, Netherlands 7th Asia Pacific Plant Biology and Plant Science Congress May 01-02, 2019 Seoul, South Korea25th Asia Pacific Biotechnology Congress May 01-02, 2019 Kyoto, Japan6th Annual Congress on Biology and Medicine of Molecules June 10-12, 2019 Helsinki, Finland10 th Tissue Repair and Regeneration Congress June 10-12, 2019 Helsinki, Finland2nd Annual Biotechnology Congress July 31-Aug 01, 2019 Chicago, USAGenetics Stemcell 2019 Tokyo, JapanMolecular Medicine 2019 Dubai, UAEInternational Cystic Fibrosis Conference: A cure for all September 20-21, 2018 Dubai, UAE

Originally posted here:
Peer Reviewed Genetics and Molecular Biology Journals ...

About Conference

ME Conferences invites all the participants from all over the world to attendNanomedicine and Nanotechnology in Health CareDuring 17-19 September, 2018 at Abu Dhabi, UAE. This includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions. And it provides an opportunity to learn about the complexity of the Diseases, discuss interventional procedures, look at new and advances in Nanotechnology and their efficiency and efficacy in diagnosing and treating various diseases and also in Healthcare treatments.

ME Conferences organizes 1000+ Global Events Every Year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open access journals which contains over 1,00,000 eminent personalities, reputed scientists as editorial board and organizing committee members. ME Conferences journals have over 5 million readers and the fame and success of the same can be attributed to the strong editorial board which contains over 30000 eminent personalities and the rapid, quality and quick review processing.ME Conferences make the perfect platform for global networking as it brings together renowned speakers and scientists across the globe to a most exciting and memorable scientific event filled with much enlightening interactive sessions, international workshops, world class international exhibitions and poster presentations.

Why to attend?

This Conference Nanomedicinemeet 2018 will focus on Healthcare and Medicine. World-renowned speakers, the most recent techniques, tactics, and the newest updates in fields Nanotechnology and Engineering, Medical Nanotechnology, Tissue Engineering are hallmarks of this conference. Nanomedicinemeet-2018 is an exciting opportunity to showcase the modern technology, the new products of your company, and/or the service your industry may offer to a broad international audience. It covers a lot of topics and it will be a nice platform to showcase their recent researches on Nanotechnology, MaterialScienceand other interesting topics.

Target Audience:

The termNano medicineencompasses a broad range of technologies and materials. Types of nanomaterials that have been investigated for use as drugs,, drug carriersor other Nonmedical agents. There has been steep growth in development of devices that integrate nanomaterials or other nanotechnology. Thenanotechnology-based medical devices market is categorized into three major segments, namely, therapeutic applications, diagnostics applications, and research applications. Rising incidence of lifestyle and age-related disorders (such as cardiovascular and hearing disorders) has contributed significantly to the growth of the nanotechnology-based active implantable devices market. Nanotechnology, or systems/device manufacture at the molecular level, is a multidisciplinary scientific field undergoing explosive development. The genesis of nanotechnology can be traced to the promise of revolutionary advances across medicine, communications and genomics. On the surface, miniaturization provides cost effective and more rapidlyfunctioningbiological components. Less obvious though is the fact that Nanometer sized objects also possess remarkableself-ordering and assemblybehaviors under the control of forces quite different from macro objects.

Advances in technology have increased our ability to manipulate the world around us . Nanotechnology is rapidly emerging within the realm of medicine. Nanomedicine is the process of diagnosing, treating, and preventing disease andtraumatic injury, of relieving pain, and of preserving and improving human health, using molecular tools and molecular knowledge of the human body. An exciting and promising area of Nano technological development is the building of Nanorobots. Highly precise positioning techniques are required in Miniaturing in chip technology, optics , micro mechanic, medicine , gene and biotechnology. The new manipulation technology is the desire to enter the micro and Nano world not only by viewing but also acting, alteringmicro andNanosized objects. Nanorobots plays a critical roles for many applications in the human body, such astargetingtumoral lesionsfor therapeutic purposes, miniaturization of the power source with an effective onboard controllable propulsion and steering system have prevented the implementation of such mobile robots.

The therapeutic properties of light have been known for thousands of years, but it was only in the last century that photodynamic therapy (PDT) was developed. It is an emerging modality for the treatment of a variety of diseases that require the killing of pathological cells (e.g. cancer cells or infectious micro-organisms) or the removal of unwanted tissue (e.g. neovascularization in the choroid or atherosclerotic plaques in the arteries). It is based on the excitation of nontoxic photosensitizers.Photodynamic therapy(PDT) uses the combination of dyes with visible light to produce reactive oxygen species and kill bacteria and destroy unwanted tissue. Nanotechnology plays a great role insolubilizing thephotosensitizers, metal nanoparticles can carry out Plasmon resonance enhancement, andfullerenescan act as photosensitizers, themselves.

Nanotechnology is becoming increasingly important for the several sectors. Promising results and applications are already being developed in the areas of nutrient delivery systems through bioactive Nano encapsulation,biosensorsto detect and quantifypathogens organic compounds. The sensitivity and performance of biosensors is being improved by using nanomaterials for their construction. The use of these nanomaterials has allowed the introduction of many new signal transduction technologies in biosensors. Many scientists have involved themselves to know the application and the benefits of nanotechnology in different areas of food industry that include bioactive Nano encapsulation, edible thin film, packages andNano sensors.

Green chemistry and Nano science are both emerging fields that take advantage of molecular-level designing and have enormous potential for advancing our science. Nano science is the study of materials that are on the length-scale of 100 nanometers or smaller and have properties that are dependent on their physical size. The principles of green chemistry can guide responsible development of Nano science, while the new strategies of Nano science can fuel the development ofgreener productsand processes.Phytochemicalsoccluded in tea have been extensively used as dietary supplements and as naturalpharmaceuticalsin the treatment The parallel development of green chemistry and Nano science and the potential synergy of the two fields can lead to more successful and profitable technologies with reduced environmental impacts and improved conservation of resources. In recent years, green synthesis ofmetal nanoparticlesis an interesting issue of the nanoscience.

Nanotechnologyis enabling technology that deals with Nano-meter sized objects. It is expected that nanotechnology will be developed at several levels: materials, devices and systems. The combination of biology and nanotechnology has led to a new generation ofNano devicesthat opens the possibility to characterize the chemical, physical, mechanical, and other molecular properties. And it can be even used to characterize the single molecules or cells at extraordinarily high throughput.Nanoparticleswith distinctive chemical compositions, sizes, shapes, and surface chemistries can be engineered easily and this technique has wide range of applications in biological systems.Utility of nanotechnology to biomedical sciences imply creation of materials and devices designed tointeraction in sub-cellular scaleswith a high degree of specificity.

Biopolymer nanoparticles are offering numerous advantages which embrace the simplicity of their preparation from well-understood biodegradable, biocompatible polymers and their high stability inbiological fluidsduring storage. Since the emergence of Nanotechnology in the past decades, the development and design of organic andbioorganic nanomaterialshas become an important field of research. And several types of polymers have been tested and are used in drug delivery systems; including nanoparticles, dendrimers, capsosomes and micelles. Researchers have found, the synthesized polymers even serves as a good carrier and plays a vital role in carrying a drug. And in other hand they are used in food industries too for food package purposes. There are thousands of organic chemicals are in present in various pharmaceutical to consumer product and are being used in dyes, flavoring agents. It can be explained in organic compounds ranging in diameter from 10 to 1m.Ultrafine particlesare the same asnanoparticlesand between 1 and 100 nanometers in size, fine particles are sized between 100 and 2,500 nanometers, and coarse particles cover a range between 2,500 and 10,000nanometers.

The biological synthesis ofnanoparticlesis synthesis method through which we can control, size and shape of nanoparticles and it increasingly regarded as a rapid, ecofriendly, and easily scaled-up technology. Over the past few years researches have shown their interest inmetallic nanoparticlesand their synthesis has greatly increased. However, drawbacks such as the involvement oftoxic chemicalsand the high-energy requirements of production. Synthesizing living organisms such as bacteria, fungi and plants is an alternative way to overcome the drawbacks. Plant mediated synthesis of nanoparticles is the green chemistry that connects. Generally, metal nanoparticles are synthesized and stabilized by using physical and chemical: the chemical approach, such as chemical reduction,electrochemical techniques,photochemical reactionsin reverse micelles. There is a growing attention to biosynthesis the metal nanoparticles using organisms. Among these organisms, plants seem to be the best candidate and they are suitable for large scale biosynthesis of nanoparticles.

Nanoparticles used asdrug deliveryvehicles are generally below 100 nm , and are coated with different biodegradable materials such as natural or synthetic polymers (PEG,PVA,PLGA,etc.), lipids, or metals , it plays significant role on cancer treatment as well as it holds tremendous potential as an effective drug delivery system. A targeted drug delivery system (TDDS) is a system, which releases the drug in a controlled manner. Nanosystems with different compositions and biological properties have been extensively investigated for drug and gene delivery applications. To achieve efficient drug delivery it is important to understand the interactions ofNanomaterialswith the biological environment, targetingcell-surface receptors, drug release, multiple drug administration, stability of therapeutic agents. Nanotechnology refers to structures roughly in the 1100 nm size regime in at least one dimension. Despite this size restriction, nanotechnology commonly refers to structures that are up to several hundred nanometers in size and that are developed bytop-down or bottom-up engineering of individual components.

Nanosuspention formulation can be used to improve the solubility of the poorly soluble drugs. One of the major problems associated with poorly soluble drugs is very low bioavailability. The Preparation ofNanosuspentionis simple and applicable to all drugs which are water insoluble. It consists of the pure poorly water-soluble drug without any matrix material suspended in dispersion . Various techniques are used for the enhancement of the solubility of poorly soluble drugs which include physical and chemical modifications of drug and other methods like particle size reduction,crystal engineering, salt formation, solid dispersion, use ofsurfactant, complexation A range of parameters like solubility, stability at room temperature, compatibility with solvent, excipient, andphotostabilityplay a critical role in the successful formulation of drugs. Use of some drug which is potentially restricted because of its toxic side-effects and its poor solubility, making it unsuitable for intravenous use in patients withdrug malabsorption.

Nano medicine drives the convergence of nanotechnology and medicine it is delineated as the application of nanotechnology in healthcare. The field of tissue engineering has developed in phases: initially researchers searched for inert biomaterialsto act solely as replacement structures in the body. Tissue engineering is classified as an associate field of biomaterialsand engineering. It focuses on the use of cellular and material-based therapies aimed attargeted tissue regenerationcaused by traumatic, degenerative, and genetic disorders.It covers a broad range of applications, in practice the term has come to represent applications that repair or replace structural tissues (i.e., bone, cartilage, blood vessels, bladder, etc.). Today, these Nano scale technologies are coming to the forefront in medicine because of their biocompatibility, tissue-specificity, and integration and ability to act as therapeutic carriers.

Polymeric nanoparticles (NPs) are one of the most studied organic strategies for Nano medicine. Intense interest lies in the potential ofpolymeric NPsto revolutionize modern medicine. Polymeric NPs include drug delivery techniques such as conjugation and entrapment of drugs,prodrugs, stimuli-responsive systems,imaging modalities, and theranostics.The use of biodegradable polymeric nanoparticles (NPs) for controlled drug delivery has shown significanttherapeutic potential. Concurrently, targeted delivery technologies are becoming increasingly important as a scientific area of investigation. Polymericnanoparticles-based therapeutics show great promise in the treatment of a wide range of diseases, due to the flexibility in which their structures can be modified, with intricate definition over their compositions, structures and properties. Advances in polymerizationchemistries and the application of reactive, efficient andorthogonal chemicalmodification reactionshave enabled the engineering of multifunctional polymericnanoparticles.

In recent years,microbubbleand Nano bubble technologies have drawn great attention due to their wide applications in many fields of science and technology, such as water treatment,biomedical engineering, and nanomaterials.Nano bubblesexhibit unique characteristics; due to their minute size and high internal pressure, they can remain stable in water for prolonged periods of time. Nanobubbles can be created whengold nanoparticlesare struck by short laser pulses. The short-lived bubbles are very bright and can be made smaller or larger by varying the power of the laser. Because they are visible under a microscope, nanobubbles can be used to either diagnose sick cells or to track the explosions that are destroying them.

Natural productshave been used in medicine for many years. Many top-sellingpharmaceuticalsare natural compounds or their derivatives.. And plant- or microorganism-derived compounds have shown potential as therapeutic agents against cancer, microbial infection, inflammation, and other disease conditions. Natural products had huge success in the post-World War II era as antibiotics, and the two terms have become synonymous.While large pharmaceutical companies have favored screening synthetic compound libraries for drug discovery, small companies have started to explore natural products uses against cancer, microbial infection, inflammation, and other diseases.The incorporation of nanoparticles into a delivery system for natural products would be a major advance in the efforts to increase their therapeutic effects. Recently, advances have been made showing that nanoparticles can significantly increase the bioavailability of natural products bothin vitro and in vivo.

Nanoscience and nanotechnology are new frontiers of this century and food nanotechnology is an emerging technology. Food technology is regarded as one of the industry sectors where nanotechnology will play an important role in the future. The development of new products and applications involving nanotechnologies holds great promise in different industrial sectors, Nanotechnology may revolutionize the food industry by providing stronger, high-barrier packaging materials, more potentantimicrobial agents. Several possibilities exist to exploit the benefits of nanotechnologies during different phases of the food chain with the aim to enhance animal nutrition and health. Several complex set of engineering and scientific challenges in the food and bioprocessing industries for manufacturing high quality and safe food through efficient and sustainable means can be solved through nanotechnology. Bacteria identification and food quality monitoring using biosensors; intelligent, active, and smart food packaging systems; and Nanoencapsulationofbioactive food compoundsare few examples of emerging applications of nanotechnology for the food industry.

The main current applications of Nanotechnology for surgeons are in the areas of development of surgical implants using Nanomaterials, Imaging, Drug Delivery and development of Tissue Engineering products, such as scaffolds with enhanced materialcell interaction. An example of this is the development of a scaffold for delivery of stem cells to replace defective retinal pigmented epithelial cells in age-related Macular Degeneration. In Dentistry research has been done, liposomal Nanoparticles that contained collagenase and performed tests with them in rats, and found compared to conventional surgery, collagenase weakened the collagen fibers, making it easier to shift the teeth afterward with braces.

Nanoparticles with their unique size-dependent properties are at the forefront of advanced material engineering applications in several fields. Metals, non-metals, bio-ceramics, and manypolymeric materialsare used to produce nanoparticles of the respective materials. These are functional in producing liposomes, PEG and many more. Due to their small size nanoparticles has found to be interacting with human bodies same like of gases. Nanoparticles of the same composition can display behavioral differences when interacting with different environments. Nanoparticles can enter the human body via inhalation, ingestion, or skin contact. The range of pathologiesrelated to exposure tonanoparticles encompasses respiratoryand even several organs and leads to diseases. Accurate in vitro assessment ofnanoparticle cytotoxicityrequires a careful selection of the test systems. Due to high adsorption capacity and optical activity, engineered nanoparticles are highly potential in influencing classical cytotoxicity assays.

One of the exciting features of nanotechnology is its utility in the field of Nano medicine, therapeutics, and medical devices . When these small size materials are introduced into biological systems, their extremely small size and their unique Nano scale properties make it possible to use them as delivery vectors and probes for biological diagnostics,bioimagingand therapeutics. In fact, when size decreases, thesurface area to volume ratioof materials becomes very large, so that a vast suitable surface is available forchemical interactions withbiomolecules. This critically implied that nanotechnology is facing a transition into the tangible advancement ofhuman therapeutics. Recently, There are multiple clinical trials of nanomaterials have done; both for therapeutics and for medical devices.

Related conferences: Nanomedicine Conferences | Nanotechnology Events | Nano Healthcare Congress | Nanomedicine Meet | Nanoscience Event | Nanoengineering Conference | Tissue Engineering Meeting

Related Societies:

USA:International Organization of Materials, International Association of Nanotechnology, Graphene Stakeholders Association, Nano Science and Technology Institute (NSTI),NanoBusiness Commercialization Association, Alliance for Nanotechnology in Cancer,International association of nanotechnology,National Institute for Nanotechnology, Waterloo Institute for Nanotechnology, The Institute for Molecular Manufacturing (IMM),NanoBusiness Alliance, Nanotechnology and Nanoscience Student Association (NANSA),Nano Science and Technology Institute (NSTI),National Cancer Institute, National Nanotechnology Initiative,American Nano society, Metals and Minerals Societies, Society for Advancement of Material and process Engineering,American Composites Manufacturers Association, Brazilian Composites Materials Association,Canadian Biomaterials Society, American Institute of Aeronautics and Astronautics (AIAA).

Europe:International Union of Crystallography, European Nanoscience and Nanotechnology Association (ENNA),German Association of Nanotechnology, Nanotechnology Industries Association, The Institute of Nanotechnology (IoN), Nanotechnology Industries Association (NIA),Russian Society of Scanning Probe Microscopy and Nanotechnology, Society of Nanoscience and Nanotechnology, Federation of Materials Societies, Society for Biomaterials, Federation of European Materials Societies

Asia-Pacific & Middle East:Nano Technology Research Association (NTRA), Asian Nanoscience and Nanotechnology Association (ANNA), Nanoscience & Nanotechnology, ASPEN-Asian society of precision engineering and nanotechology, The International Association of Nanotechnology (IANT), Iran Nanotechnology Initiative Council (INIC), National Institutes of Health, Society of Materials Science, Japan Society for Composite Materials, Australasian Society for Biomaterials and Tissue Engineering, Australasian Ceramic Society, Materials Research Society, National Centre for Nanoscience and Technology.

Theme: Role of Nanotechnology in Humans life

Summary:

The field of Nanotechnology has recently emerged as the most commercially viable technology of this century because of its wide-ranging applications in our daily lives. Man-made Nanostructured materials such as fullerenes, nanoparticles, Nano powders, Nanotubes, Nanowires, Nanorods, Nano-fibers, Quantum dots, Dendrimers, Nano clusters, Nanocrystals, and Nanocomposites are globally produced in large quantities due to their wide potential applications, e.g., in skincare and consumer products, healthcare, electronics, photonics, biotechnology, engineering products, Pharmaceuticals, drug delivery, and agriculture. Many emerging economies such as Brazil, China, India, Iran, UAE, Malaysia, Mexico, Singapore and South Africa have ambitious research and development (R&D) plans for Nanotechnology.A group of scientists who have mapped out the uses of Nanotechnology and the needs of global health argue that Nano medicine is relevant for the developing world. They surveyed researchers worldwide and concluded that Nanotechnology could greatly contribute to meeting the Millennium Development Goals for health.

Importance and scope:

Nanotechnologyis becoming a crucial driving force behind innovation in medicine and healthcare, with a range of advances including Nano scale therapeutics, biosensors, implantable devices, drug delivery systems, and imaging technologies. Universities also have begun to offer dedicated Nano medicine degree programs (example:MSc program in Nanotechnology for Medicine and Health Care). Nanotechnology will be getting to be progressively prevalent these times Around learners. Actually, if you follow again of the Inception about nanotechnology, you will discover that Ayurveda need long been utilizing gold Also silver nanoparticles, known as bhasmas, to treat Different therapeutic ailments. Presently, nanotechnology may be generally utilized within huge numbers industries, going from cosmetics, agriculture, and materials should pharmaceutical Also human services. Nanomedicine may be the provision for nanotechnology for those diagnoses, detection, and medicine Also aversion of illnesses. Presently there need aid various items on the business that would the outcome from claiming nanotechnology. Talking for scratching the surface, we likewise have Nano auto wax that fills done the individuals minor cracks more successfully Furthermore provides for you a shinier vehicle. There need aid likewise Nano items accessible with stay with your eyewear What's more different optical units cleaner, dryer, What's more that's only the tip of the iceberg tough.

Conference highlights:

Why in Abu Dhabi?

Abu Dhabi is the federal capital and centre of government in the United Arab Emirates sits off the mainland on an island in the Persian (Arabian) Gulf. It is the largest city of the Emirate of Abu Dhabi and one of the most modern cities in the world. It is a well-ordered, industrious city with a pretty waterside location. Innovative Nano Technology LLC was founded in the beginning of 2016 in Al Ain City, Abu Dhabi, United Arab Emirates. It was established with the goal of taking a leading role in the field of Nano Technology Based Coatings, and is considered as one of the first Companies who offer the new Nano technology based Coatings in the region.

Why to attend?

United Arab Emirates has a number of universities that offer research and educational opportunities in nanotechnology. United Arab Emirates University, The first and foremost comprehensive National University in the United Arab Emirates. eFORS office is the University consultancy office within the college of engineering that deals with several science and technology issues including Biochemical and Biopharmaceutical Processes and Bioengineering and Nanotechnology. Reports released during October 2012 revealed that the worlds second largest foundry, Globalfoundries has agreed to partner with Masdar Institute to develop Abu Dhabi as a centre for semiconductor R&D and manufacturing excellence. In September, the company allowed students and professors to use its technology facilities at its Abu Dhabi branch. The facilities have a laboratory-like environment with powerful production servers, engineering work stations and a high-speed data network that can be used for enabling remote access to very advanced nanotechnology engineering systems

Technology domains of patent applications in UAE

This graph shows the global Nanomedicine market size, measured in terms of revenues, such as sales revenues, grants revenues, and milestones. From2006to date, a steady growth has occurred, which is expected to continue through2014, at aCAGRof13.5% [BCCResearch, Nanotechnology in Medical Applications. The drug delivery market is the largest contributing application segment, whereas biomaterials are the fastest growing application area in this market. Nanomedicine accounts for77Marketed Products Worldwide, representing an Industry with an estimated market $249.9Billion by2016[ETPNdata,BCC].

Globally, the industry players would centering essentially once R&D to get Regard for Different clinical trials for future Nanodrugs with a chance to be economically accessible in the business sector. If a chance to be generally arranged for exactly of the most punctual What's more The greater part essential requisitions of Nano medicine for regions for example, gene treatment and tissue building. The a greater amount propelled requisitions for Nano medicine will pose interesting tests As far as order Furthermore support about exploratory dexterity.

Nano medicine market :

Nano-enabled medical products beganappearing on the market over a decade ago and some have become best-sellers in theirtherapeutic categories. The main areas in which Nanomedical products have made animpact are cancer, CNS diseases, cardiovascular disease, and infection control. At present, cancer is one of the largesttherapeutic areas in which Nano-enabled products have made major contributions; theseinclude Abraxane, Depocyt, Oncospar, Doxil,and Neulasta. Cancer is a prime focus forNano pharmaceutical R&D, and companieswith clinical-stage developments in this fieldinclude Celgene, Access, Camurus, andCytimmune. Treatments for CNS disorders includingAlzheimers disease and stroke also feature prominently in Nano therapeutic research,seeking to build on achievements already posted by products such as Tysabri, Copazone,and Diprivan. According to BCC Research,this is a field hungry for successfultherapeutic advances and annual growth fromexisting and advanced pipeline products isexpected to reach 16% over the next 5 years.

Nanotechnology Companies in Asia and Middle East:

Nano Congress 2017

We gratefully thank all our wonderful Speakers, Conference Attendees, Students, Media Partners, Associations and Sponsors for making Nano Congress 2017 Conference the best ever!

The19thNano Congress for Next Generation, hosted by the ME Conferences was held duringAugust 31- September 01, 2017atBrussels, Belgiumbased on the themeNext Generation Nanotechnology Concepts Methodologies Tools and Applications". Benevolent response and active participation was received from the Organizing Committee Members along with Scientists, Researchers, Students and leaders from various fields of Nanotechnology who made this event a grand success.

ME Conferences expresses its gratitude to the conference Moderator,namelyDr.Dominique Ausserrefor taking up the responsibility to coordinate during the sessions. We are indebted to your support.

Similarly we also extend our appreciation towards our Poster judge namely,Dr. Arturs Medvids.

The conference was initiated with theHonorable presenceof theKeynote forum. The list includes:

The meeting reflected various sessions, in which discussions were held on the following major scientific tracks:

Nano Materials Synthesis and Characterisation

Nano Photonics

Molecular Nanotechnology

Nanotechnology and Cosmetics

Nanotechnology in Agriculture and Food Industry

Carbon Based Nano materials and Devices

Nanotechnology Safety

Nano Medicine and Nano Biotechnology

Nano Science and Technology

Nano Applications

Nano-electronics

Nano Biomaterials

Nano Biometric

Advanced Nanomaterials

Nano Technology in Tissue Engineering

Nanotech for Energy and Environment

Nano Computational Modelling

ME Conferences offers its heartfelt appreciation to organizations such asAllied Academies,Andrew John Publishing Inc.,New York private Equity Forum,Crowd Reviewsand other eminent personalities who supported the conference by promoting in various modes online and offline which helped the conference reach every nook and corner of the globe. ME Conferences also took privilege to felicitate the Keynote Speakers, Organizing Committee Members, Chairs and sponsors who supported this event

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Welcome to Carolina Ophthalmology, where "excellence and experience" is more than just our slogan. We are pleased that you have chosen to visit our website and hope that the information here will assist you in learning about our practice, as well as educating yourself about the health of your eyes. Carolina Ophthalmology has been serving the people of Western North Carolina for over 35 years and our reputation for quality surgical outcomes is well established. Our physicians are highly experienced and specialty trained to treat cataracts, glaucoma, retinal disease, corneal disease, and facial aesthetic problems.

We are committed to offering the most advanced technology available to our patients. Our newest offerings include the revolutionary LenSx laser for laser-assisted cataract surgery; premium lenses for cataract surgery such as the Tecnis Symfony lens, and the ReStor lens, which reduce the dependence on glasses after cataract surgery; the ORA (OptiWave Refractive Analysis) system, new technology that measures the refractive power of the eye during cataract surgery to assist the surgeon with optimum lens selection; the Cutera Laser, a technically advanced laser that offers facial rejuvenation by treating delicate broken veins, sun damage and other skin imperfections with remarkable results; and the drug Lucentis, a breakthrough treatment for wet macular degeneration patients.

At Carolina Ophthalmology, our doctors and staff are committed to your satisfaction. Because we are a surgically based practice, we work closely with area Optometrists to ensure that all of your eye care needs are met. We recognize that each of our patients has their own unique issues and that is why we listen before we treat! Our sincere attitude, along with our experience, our technology and our tradition for excellence is something we call the "Carolina Ophthalmology Advantage" . We are proud of the tradition we have created and hope that you will become a part of that tradition!

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You may have heard about stem cell research on the nightly news, but did you know that your extracted wisdom teeth could help make a medical breakthrough? Dental stem cells are being investigated for multiple applications to help solve some of the biggest health issues we face today. Amazingly, these uses are not limited to the oral cavity.

What Exactly Are Stem Cells?

Stem cells are different from most other cells in a human body because they are not specialized, explains the National Institutes of Health. Unlike a red blood cell or a skin cell, a stem cell has the unique ability to develop into many different cell types to heal the body and replenish damaged tissue. When a stem cell multiplies, it can either form additional stem cells or grow into cells that have a more specific function, such as liver cells or muscle cells in the heart. Under experimental conditions, a stem cell can even form organ- or tissue-specific cells with specialized functions.

Unfortunately, some controversy surrounds the use of stem cells for research. Stem cells can come from multiple sources: embryonic tissue and postnatal tissue. When embryonic cells are used, they are isolated from developing fetal tissue. When postnatal cells are used, they are typically referred to as adult stem cells and come from a fully developed animal or human child or adult. Stems cells from oral tissues are always adult stem cells and are often donated by living adults for their own use from their own extracted teeth or oral tissue.

What Is So Unique About Dental Stem Cells?

According to the Journal of Natural Science, Biology and Medicine, the stem cells that come from oral tissues are ideal for use in research since they are readily accessible and can be harvested noninvasively. These cells have the potential to be used in multiple clinical applications, such as regenerative dentistry.

As explained in the Journal of Tissue Engineering, dental stem cells can be obtained from a number of oral tissues, including the craniofacial bones, periodontal ligament, dental pulp, tooth germ, dental follicle, oral mucosa, apical papilla, gingiva and periosteum. The easiest sources from which to obtain these cells are the pulp of exfoliated deciduous teeth and extracted wisdom teeth. Your patients may be excited to learn that if they lose a tooth and it is donated to research, it may potentially help with the development of treatments for others with debilitating diseases.

Potential Uses for Dental Stem Cells

One of the most impressive qualities of dental stem cells is their wide variety of potential applications. In in vitro studies, these cells were found to create dentin-like structures and to differentiate into osteoblast-like cells that built bone, leading to research surrounding regeneration of dental tissues.

Additionally, stem cells' versatility makes them promising for treating degenerative conditions, such as stroke, Alzheimer's disease, multiple sclerosis, Parkinson's disease, cirrhosis, arthritis, cardiac defects and spinal cord injuries. Stem cell-grown pancreatic cells may even be able to produce insulin and reverse hyperglycemia in patient who have diabetes. All of this potentially from a tooth!

Takeaways

Why It's Important

Keeping up with research on dental innovations and research can help you stay informed and be a source of knowledge for your patients. Someday, you may even help them contribute to science and medicine by donating a lost tooth.

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