StemCell Therapy

Journal of Regenerative Medicine Journal of Regenerative Medicine (JRGM) is a peer-reviewed scholarly journal and aims to publish the most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all areas of stem cells and regenerative medicine and making them available online freelywithout any restrictions or any other subscriptions to researchers worldwide. Journal of Regenerative Medicine focuses on the topics include regenerative medicine therapies, stem cell applications, tissue engineering, gene and cell therapies, translational medicine and tissue regeneration. The Journal is using Editorial Manager System for quality in review process. Editorial Manager is an online manuscript submission, review and tracking system. Review processing is performed by the editorial board members ofJournal Regenerative Medicine or outside experts; at least two independent reviewers approval followed by editor approval is required for acceptance of any citable manuscript. Authors may submit manuscripts and track their progress through the system, hopefully to publication. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process. Interested authors can submit manuscript through Online Submission System or Editorial Manager or send as an e-mail attachment to the Editorial Office ateditor.jrgm@scitechnol.com oreditor.jrgm@scitechnol.org Journal of Regenerative Medicine is organizing & supporting3rd International Conference on Tissue Science & Regenerative Medicine during September 24-26, 2014 Valencia, Spain with the theme ofBreakthrough Strategies for Tissue Engineering, Repair & Regeneration.

*Unofficial 2014 Impact Factor was established by dividing the number of articles published in 2012 and 2013 with the number of times they are cited in 2014 based on Google search and the Scholar Citation Index database. If X is the total number of articles published in 2012 and 2013, and Y is the number of times these articles were cited in indexed journals during 2014 than, impact factor = Y/X.

Heterogeneity of Stem Cells in Human Amniotic Fluid

Amniotic fluid contains a mixture of cells with capacity to differentiate into all germ layers. These cells are present in large numbers in midtrimester samples obtained for cytogenetic diagnosis, and have been identified by stem cell surface markers and transcription factors. We studied cultured samples from patients who had both direct cultures and matched cultures obtained 2 weeks later from the cytogenetics laboratory as well as patients with cytogenetics material only. Samples were cryogenically frozen, thawed, expanded in culture with excellent viability. There was considerable individual variation unrelated to gestational age or telomere length. Phenotype for embryonic markers was assessed by flow cytometry and by quantitative polymerase chain reaction. The most consistently present stem cell markers in substantial amounts were CD90, SSEA-4, & TRA-1-60. Cells with CD90, SSEA-4 & TRA-1-60 double and triple labeled also could be identified and subcultured, confirming the heterogeneity of the amniotic fluid stem cell population.

Patent Knowledge and Stem Cell Scientists

The knowledge economy is progressing at a rapid pace and increasingly relying on intangible assets as a form of recoupling its investments. Intangible assets include intellectual capital and intellectual property, with an emphasis on patents here. Due to the unawareness about intellectual property rights, researchers, very often, are flying blind unaware of opportunities and threats posed by patents to their research projects. Although, the business acumen of many (private and public) scientists has markedly increased in recent years, large numbers are still left outside the patent loop of opportunities and knowledge of obstacles to their research. Knowledge about patents carries important implications for all researchers and those responsible for science and technology policy making.

Platelet-Rich Plasma Therapies:In the Right Pathway to Find their Regulatory Niche

The Spanish Agency of Medicines and Medical Devices (AEMPS) has recently regulated the use of platelet-rich plasma (PRP), that is,patients own plasma enriched in platelets and therefore in proteins and growth factors, as a human use drug. It is the first time that one regulatory agency worldwide categorizes these types of therapeutic therapies. According to AEMPS, PRP approaches cannot be considered as an advanced-therapy medicinal product. PRPs are classified as non-industrial biological medicines, being subjected to a strict regulation in terms of production, validation, efficacy and safety.

Understanding Somatic (Adult)Stem Cells: Potential vs. Reality

In the adult mammal, reserve stem cells, both active and quiescent, serve as primary precursors for differentiated cells. They often provide replacement cells as needed during normal cell homeostasis or serve as residual stem cell sources during periods of stress, trauma or disease. Adult stem cells have a defined level of maturity, accompanied by stability of differentiation, are less likely to invoke an immune response and are often readily derived from reservoirs in bone marrow, blood, adipose tissue and a variety of placental related tissues. While certain adult stem cells are well established as normal cell precursors and used in the treatment of diseases, an expanding array of specific adult stem cells from muscle, heart, nervous tissue, etc. are being discovered and posited as cell progenitors for regenerative therapy. Current preclinical and clinical tests are designed to test the identity, safety, efficacy, and methodology of harvested stem cells or derived cell lines for therapy of specific disorders. Contemporary therapeutic venues, bio-cell, drug and treatment centers have proposed the use of specific adult stem cells for human therapy in regenerative medicine.

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Regenerative Medicine Journals | Stem Cell Articles List

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