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Archive for the ‘Biotechnology’ Category

International Biotechnology Conferences | Biotechnology …

Thursday, November 22nd, 2018

About Conference

Registration and abstract submission now open

EuroSciConis glad to welcome all the participants to24thEdition of International Conference on Biotechnologyschedule onApril 15-16, 2019inParis, France. The conference Theme:"Highlighting Latest Advancements and Applications of Biotechnology for Future Challenges"that focuses to share novel approaches related to biotechnology and exploring the challenges concerning excellence in research and advancements, we are pleased to invite allBiotechnologists, Professors,Researchers,scientists, Business Giants, CEOs, COOs, Directors, Vice Presidents, Co-directors, Managing Directors, Industry Safety Officers, Environmental & Plant Scientists, Post Doctorate Fellows, Vendors of Consumer Products/ Managers, Pharmaceutical Scientists, Students from the Biotechnology and its allied areas.

ThisInternational Biotechnology Conferencesproceedings include symposiums and workshops, keynote speeches, plenary talks, poster sessions and panel discussion on latest research developments in the field ofBiotechnology.

EuroSciConis the longest running independent life science events company with a predominantly academic client base. Our multi professional approach creates a unique experience that cannot be found with a specialist society or commercially.

Euroscicon are corporate members of the following organisations:

Conference Topics:

Medical Biotechnology

Pharmaceutical Biotechnology

Biomedical Engineering and Bio-Engineering

Enzyme & Protein Engineering

Nanobiotechnology

Plant Biotechnology

Marine Biotechnology

Food & Feed Biotechnology

Animal Biotechnology

Cell Science & Cell Biology

Applied Biotechnology

Bio-Safety and Bioethics

Business Development

Microbial Biochemistry

Advancements In Biotechnology

Bioproducts and BioEnergy

Reproductive Biotechnology

Bioremediation and Biodegradation

Biotechnology

Nutritional Biotechnology

Environmental Biotechnology

Stem Cell Biotechnology

Industrial Biotechnology and Fermentation techniques

Genomics and Proteomics

Genetic Engineering and rDNA Technology

Biomaterials and Regenerative Medicine

Chemistry & System Biology

Biotechnology & Intellectual Property Rights

Cell Biology and Immunology

Bioinformatics and Biosensor

Biochemistry

Biophysics

Cell, Gene Therapy & DNA Repair

Industrial Biotechnology

Biotechnology And Bioprocess Engineering

Opportunities for Conference Attendees:

For Researchers & Faculty:

For Universities, Associations & Societies:

For Students & Research Scholars:

For Business Delegates:

For Companies:

Medical Biotechnology

Medical biotechnology refers to amedicinalor diagnostic product or a vaccine that consists of or has been produced in living organisms and may be manufactured via recombinant.Medical Biotechnology has a tremendous impact on meeting the needs of patients and their families as it not only encompasses medicines and diagnostics that are manufactured using abiotechnological process, but alsogeneandcell therapiesandtissue engineeredproducts. Today, the majority of innovativemedicines, whether manufactured usingbiotechnologyor via achemical synthesislike a traditional smallmolecule medicine, as well as many diagnostic products, are made available by applying modernbiotechnologyin their development and manufacturing

Pharmaceutical Biotechnology

Pharmaceutical biotechnologyis a comparatively new and growing field in which the principles ofbiotechnologyare applied to the designing and production ofdrugs.Pharmaceuticalcompanies manufacture and marketdrugs, livestockfeed supplements,vitamins, and a host of other products. Consistently,Pharmaceuticalcompanies are one of the most profitable industries in the U.S. with sales exceeding $320 billion per year.

Biomedical Engineering and Bio-Engineering

Biomedical engineering, orbioengineering, is the application of engineering principles to the fields of biology and health care.Bioengineerswork with doctors,therapistsandresearchersto develop systems, equipment and devices in order to solveclinical problems.

Biomedical engineershave developed a number of life-enhancing and life-saving technologies. These include:

Prosthetics, such asdenturesandartificial limbreplacements.

Surgical devices and systems, such as robotic and laser surgery.

Systems to monitor vital signs and blood chemistry.

Implanted devices, such asinsulin pumps, pacemakers and artificial organs.

Imaging methods, such as ultrasound, X-rays, particle beams and magnetic resonance.

Diagnostics, such as lab-on-a-chip and expert systems.

Therapeutic equipment and devices, such as kidney dialysis and transcutaneous electrical nerve stimulation (TENS).

Radiation therapy using particle beams and X-rays.

Physical therapy devices, such as exercise equipment and wearable tech.

Nanobiotechnology

Nano biotechnology is the multidisciplinary subject which combines engineering principles and molecular biology.Nano biotechnologyhas the potentiality to createbiological and biochemicalmaterials and devices at molecular and atomic levels. It presents new class of multifunctional systems and devices for biological analysis with better sensitivity and much specificity. Nano biotechnology subsumes the application of the tools and processes of nanotechnology to control biological systems. The Nano biotechnology includes new techniques such as3D imagininglive cells, real-time imaging, and single molecule imaging bio analytical microarrays and biosensors and microfluidic devices. This discipline helps to indicate the subsume of biological research with various fields of nanotechnology. Concepts that are enhanced through Nano biology comprises: Nano devices (such as biological machines), nanoparticles, and Nano scale phenomena that available within the discipline of nanotechnology. This technical approach to biology allows scientists to envisage and create systems that can be used for biological research.Biologicallyinspired nanotechnology uses biological systems as the encourisation for technologies not yet created. However, as with nanotechnology and biotechnology, bio nanotechnology does have many potential ethical issues associated with it.

Microbial Biochemistry

For thousands of years,microorganismshave been used to supply products such as bread, beer and wine. A second phase of traditional microbial biotechnology began during World War I and resulted in the development of the acetone-butanol andglycerol fermentations, followed by processes yielding, for example, citric acid, vitamins and antibiotics. In the early 1970s,traditional industrial microbiologywas merged withmolecular biologyto yield more than 40 biopharmaceutical products, such aserythropoietin, humangrowth hormoneandinterferons. Today, microbiology is a major participant in global industry, especially in the pharmaceutical, food and chemical industries.

Advancements In Biotechnology

Biotechnology as the name indicates that based on technology the progression of biology. Nowadays the whole world relies on technologies, into that where biology is our Base of life, & when scientists are using technology in biology it is doing wonders. Biotechnology can be used in several fields and sectors. For example in medical therapy, in war-fields (Bio--weapons), In agricultural biology, in reproductive biology, in cell biology, in genetic engineering. There is endless ways in which biotechnology is being used. It is a great combination which actually has the ability to change the impossible into possible.

Industrial Biotechnology and Fermentation techniques

Industrial or white biotechnology uses enzymes and micro-organisms to make bio based products in sectors such as chemicals, food and feed, detergents, paper and pulp, textiles and bioenergy. The application of industrial biotechnology has been proven to make significant contributions towards mitigating the impacts of climate change in these and other sectors. In addition to environmental benefits, biotechnology can improve industrys performance and product value and, as the technology develops and matures, white biotechnology will yield more and more viable solutions for our environment. These innovative solutions bring added benefits for both our climate and our economy.

Genetic Engineering and rDNA Technology

Genetic engineering is the manipulation of an organism's genome using biotechnology Principles. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species domains for the production of improved or novel organisms. Genetic engineering has applications in medicine, research, industry and agriculture and can be used on a wide range of plants, animals and microorganisms. Tissue engineering is the use of a integration of cells, engineering and materials principles, and suitable biochemical and physicochemical factors to improve or replace biological tissues.

Plant and Agriculture Biotechnology:

Agricultural biotechnology is the area of biotechnology involving applications to agriculture. Agricultural biotechnology has been practiced for a long time, as people have sought to improve agriculturally important organisms by selection and breeding. An example of traditional agricultural biotechnology is the development of disease-resistant wheat varieties by cross-breeding different wheat types until the desired disease resistance was present in a resulting new variety. Modern agricultural biotechnology improves crops in more targeted ways. The best known technique is genetic modification, but the term agricultural biotechnology (or green biotechnology) also covers such techniques as Marker Assisted Breeding, which increases the effectiveness of conventional breeding. Whatever the particular technology used, the crops may be destined for use for food, biomaterials or energy production. Genetic modification means that existing genes are modified or new genes included to give plant varieties desirable characteristics, such as resistance to certain pests or herbicides, or for vitamin fortification. Because only a few genes with known traits are transferred, GM methods are more targeted and faster than traditional breeding. Biotechnology has helped to increase crop productivity by introducing such qualities as disease resistance and increased drought tolerance to the crops. Plant biotechnology is the technique used to manipulate the plants for specific needs or requirement. In traditional process seed is the major source for germinating a new plant but the advance method is independent that combines multiple needs to get the required traits.

Bioproducts and BioEnergy

Bioenergy is renewable energy made available from materials derived from biological sources. Biomass is any organic material which has stored sunlight in the form of chemical energy. As a fuel it may include wood, wood waste, straw, manure, sugarcane etc. Bio-products are the application of plant-derived resources as an alternative to non-renewable matter. This sustainable approach considers the entire product life cycle from its agricultural origin to its overall renewability. Bio based innovation in the production and content of commonly used items assures consumers of improved environmental well-being without compromising product performance.

Reproductive Biotechnology

Reproductive Biotechnology encompasses all current and anticipated uses of technology in human and animal reproduction, including assisted reproductive technology, contraception and others. Efficient reproductive performance and monitoring are imperative for sustainability in any livestock production system, especially for milk, meat, draft, and replacement animals. In recent times, there has been increasing challenges for increasing productivity and disease with altering climate. These targets, thought to some extent, can be achieved by conventional reproduction techniques. Advent and use of modern reproductive technologies have opened many avenues to study, treat and manipulate the reproductive phenomenon both in vitro and in vivo to improve reproductive performance in various domestic species of livestock.

Bioremediation and Biodegradation

Bioremediation is a term used in biotechnology which is helping in cleaning the environment. Its a process in which the microorganisms or their enzymes are used to clean up environment which is contaminated. With the help of microorganisms certain compounds that are contaminating the environment are degraded.it is one of the solutions that are used to reduce the pollution. There are 2 types of bioremediation. In Biodegredation organic compounds are degraded or broken down with the help of microorganisms. The organic compound that is degraded is usually the animal and plant waste which is converted into certain elements that are returned to the environment and are used again usually by plants. The artificial compounds may also be bio degraded but these compounds must resemble the animal or plant waste or organic compounds. With the help of this biodegradation the elements or the nutrients are returned to the environment. It is a very important process. Usually the materials like certain plastics are manufactured focusing on the aspect that it should be biodegradable which can be degraded easily into simpler compounds. Biomass is an industry term for getting energy by burning wood, and other organic matter. Burning biomass releases carbon emissions, around a quarter higher than burning coal, but has been classed as a "renewable" energy source in the EU and UN legal frameworks, because plants can be regrown. Bioenergy is renewable energy made available from materials derived from biological sources. Biomass is any organic material which has stored sunlight in the form of chemical energy.

Environmental Biotechnology

Environmental biotechnology is biotechnology that is applied to and used to study the natural environment. Environmental biotechnology could also imply that one try to harness biological process for commercial uses and exploitation. The International Society for Environmental Biotechnology defines environmental biotechnology as "the development, use and regulation of biological systems for remediation of contaminated environments (land, air, water), and for environment-friendly processes.

Marine Biotechnology

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Biotechnology – American Farm Bureau Federation

Wednesday, October 17th, 2018

Biotechnology has proven to be an important tool for better sustainability and food security. It helps farmers grow more food while improving the environment. For example, biotechnology reduces the use of costly inputs and improves weed management, allowing farmers to reduce tillage for better soil, water and air quality. Today, roughly 90 percent of corn, cotton and soybeans grown in the U.S. have been improved through biotechnology, and farmers are choosing biotech traits when growing other crops such as alfalfa, sugarbeets and canola.

Despite rapid adoption by farmers and a strong scientific consensus that biotechnology does not pose health and environmental risks, regulatory burdens are slowing research and innovation of new biotech traits and are starting to reduce U.S. farmers international competitive advantage. In addition, activist groups routinely threaten the availability of new traits by blocking science-based regulatory decisions, filing lawsuits and advocating for labeling mandates.

GM crops require less water and fewer chemical applications than conventional crops, and they are better able to survive drought, weeds, and insects.

U.S. agriculture will maintain its competitive advantage in world markets only if we continue to support innovations in technology and grasp opportunities for future biotech products.

To improve regulation of biotechnology, Farm Bureau supports:

Farm Bureau encourages efforts to educate farmers to be good stewards of biotech crops to preserve accessand marketability.

Farm Bureau believes agricultural products grown using approved biotechnology should not be subject to mandatory labeling. We supportexisting FDA labeling policies and opposestate policies on biotech labeling, identification, use and availability.

On July 29, 2016 the president signed S. 764, the National Bioengineered Food Disclosure Standard, into law. While not perfect, S. 764 was a compromise that Farm Bureau endorsed. The law creates a uniform standard for the disclosure of ingredients derived from bioengineering and allows food companies to provide that information through an on-package statement, symbol or electronic disclosure. It also created a strong federal preemption provision to protect interstate commerce and prevent state-by-state labeling laws and was effective on the date of enactment. USDA has two years to develop the disclosure standards and Farm Bureau has been an active participant in the rulemaking process.

Farm Bureau supports active involvement and leadership by the U.S. government in the development of international standards for biotechnology, including harmonization of regulatory standards, testing and LLP policies.

This resource can help set the record straight on GMOs, to correct misinformation and show why biotechnology is so important to agriculture.

Benefits of Biotech Toolkit (PDF)

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Top 18 Biotechnology ETFs – ETFdb.com

Monday, October 8th, 2018

ETF Overview

This is a list of all Biotechnology ETFs traded in the USA which are currently tagged by ETF Database. Please note that the list may not contain newly issued ETFs. If youre looking for a more simplified way to browse and compare ETFs, you may want to visit our ETFdb.com Categories, which categorize every ETF in a single best fit category.

* Assets and Average Volume as of 2018-10-05 20:19 UTC

This page includes historical return information for all Biotechnology ETFs listed on U.S. exchanges that are currently tracked by ETF Database.

The table below includes fund flow data for all U.S. listed Biotechnology ETFs. Total fund flow is the capital inflow into an ETF minus the capital outflow from the ETF for a particular time period.

Fund Flows in millions of U.S. Dollars.

The following table includes expense data and other descriptive information for all Biotechnology ETFs listed on U.S. exchanges that are currently tracked by ETF Database. In addition to expense ratio and issuer information, this table displays platforms that offer commission-free trading for certain ETFs.

Clicking on any of the links in the table below will provide additional descriptive and quantitative information on Biotechnology ETFs.

The following table includes ESG Scores and other descriptive information for all Biotechnology ETFs listed on U.S. exchanges that are currently tracked by ETF Database. Easily browse and evaluate ETFs by visiting our ESG Investing themes section and find ETFs that map to various environmental, social, governance and morality themes.

This page includes historical dividend information for all Biotechnology ETFs listed on U.S. exchanges that are currently tracked by ETF Database. Note that certain ETPs may not make dividend payments, and as such some of the information below may not be meaningful.

The table below includes basic holdings data for all U.S. listed Biotechnology ETFs that are currently tagged by ETF Database. The table below includes the number of holdings for each ETF and the percentage of assets that the top ten assets make up, if applicable. For more detailed holdings information for any ETF, click on the link in the right column.

The following table includes certain tax information for all Biotechnology ETFs listed on U.S. exchanges that are currently tracked by ETF Database, including applicable short-term and long-term capital gains rates and the tax form on which gains or losses in each ETF will be reported.

This page contains certain technical information for all Biotechnology ETFs that are listed on U.S. exchanges and tracked by ETF Database. Note that the table below only includes limited technical indicators; click on the View link in the far right column for each ETF to see an expanded display of the products technicals.

This page provides links to various analysis for all Biotechnology ETFs that are listed on U.S. exchanges and tracked by ETF Database. The links in the table below will guide you to various analytical resources for the relevant ETF, including an X-ray of holdings, official fund fact sheet, or objective analyst report.

This page provides ETFdb Ratings for all Biotechnology ETFs that are listed on U.S. exchanges and tracked by ETF Database. The ETFdb Ratings are transparent, quant-based evaluations of ETFs relative to other products in the same ETFdb.com Category. As such, it should be noted that this page may include ETFs from multiple ETFdb.com Categories.

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Top 18 Biotechnology ETFs - ETFdb.com

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Biotechnology Conferences | Biotechnology Congress | 2018 …

Monday, October 8th, 2018

About the conference

Biotechnology International Conferences invites all the participants from all over the world to attend 4thInternational Conference onAdvances in Biotechnology and Bioscience during November 15-17, 2018 in Berlin, Germany which includes prompt keynote presentations, Oral Talks, Poster Presentations, Exhibitions.

Biotechnologyis a field which interrelates biological sciences with engineering technologies to increase living organisms and biological systems to produce products . We bring together a diversity of disciplines that complement one another to unravel the complexity of biology. We incorporate the physical sciences, engineering, mathematics, computational and bioinformatics, and the social sciences, as appropriate, to problems we are addressing. We work with animals, plants and microorganisms and our research span the levels of the biological hierarchy from molecules to ecosystems.Bioscienceis defined as technologies that relate to therapeutic or diagnostic products or services, including medical devices and digital health technologies that improve human health. Also included in the state definition are technologies that rely on research to improve agricultural output. As name Bioscience reflects a belief that the study of biological systems is best approached by incorporating many perspectives.

Biotechnology International organizeconferences of 1000+ Global Events inclusive of 300+ Conferences, 500+ Upcoming and Previous Symposiums and Workshops in the USA, Europe & Asia with support from 1000 more scientificsocietiesand publishes 700+Open access journalswhich contains over 30000 eminent personalities, reputed scientists as editorial board members.

Why to attend???

This unique international conference provides a platform for researchers and decision makers in Biotechnology and Bioscience to present their latest findings and learn about all the important developments in Biotechnology and Bioscience. Many scientists and world's renowned experts will participate in the conference. Throughout the course of the two-day conference, you will have the opportunity to both networks and hear leaders from the international academic and corporate bioscience communities.

Target Audience:

The conference will attract a large group of scientists and researchers from around the globe. Delegates will have a valuable, informative and positive experience.

Track: Biotechnology

Biotechnologyis the usage of living systems and organisms to develop or make products, mark or modify products or processes for specific use". Science and innovation have in the past presumed an indispensable part in enhancing general wellbeing.Biotechnology has noteworthy applications in therapeutics, diagnostics, genetically modified crops for agriculture, processed food, bioremediation, waste treatment, and energy production. Biotechnology has likewise prompted to the advancement of anti-infection agents.

Related Biotechnology Conferences | Genetic Engineering Conferences | Pharmaceutical Chemistry Conferences | Biological Engineering Conferences | Bio economy Conferences | Biomedicine Conferences | Microbiology Conferences | Molecular Biology Conferences | Nano-Biotechnology Conferences | Biology Conferences | Embryology Conferences | Pharmacogenomics Conferences

21st European Biotechnology Congress, October 11-13, 2018 Moscow, Russia; 22nd Global Biotechnology Congress September 10-11, 2018 Stockholm, Sweden; 4th Synthetic Biology Conferences October 18-19, 2018 Rome, Italy; 4th Tissue Engineering Conferences; October 18-19, 2018 Rome, Italy; 11th Tissue Engineering Conferences October 18-20, 2018 Rome, Italy; 11th Regenerative Medicine Conferences October 18-20, 2018 at Rome, Italy; The 2nd edition of Biotech France 2018 International Conference and Exhibition June 27 -29, 2018 Paris, France; BIO World Congress on Industrial Biotechnology July 16 - 19, 2018 Philadelphia, Pennsylvania; World Biotechnology Conference June 25-27, 2018 Stockholm, Sweden; International Biotechnology and Research Conference April 25-27, 2018 Rome, Italy

Related Societies:

Europe: Spanish Society of Biotechnology, The Pharmaceutical Society of Ireland, Russian Medical Society, Society for Engineering in Agriculture, Society of Microbial Ecology and Disease, Manchester University Pharmaceutical Society, Italian Society of Biochemistry and Molecular Biology, European Society for Precision Engineering and Nanotechnology, Society for Chemical Engineering Biotechnology, Romanian Society of Medical Mycology and Mycotoxicology, New Zealand Plant Protection Society, International Society for Pharmaceutical Engineering, Pharmaceutical Society of Australia.

Related Societies:

Related Societies:

Related Societies:

Related Societies:

Related Societies:

Related Biotechnology Conferences | Genetic Engineering Conferences | Pharmaceutical Chemistry Conferences | Biological Engineering Conferences | Bio economy Conferences | Biomedicine Conferences | Microbiology Conferences | Molecular Biology Conferences | Nano-Biotechnology Conferences | Biology Conferences | Embryology Conferences | Pharmacogenomics Conferences

4th Glycobiology World Congress September 17-19, 2018 Rome, Italy; 13th Metabolomics Conferences October 11-12, 2018 Zurich, Switzerland; 13th Systems Biology Conferences October 11-12, 2018 Zurich, Switzerland; 14th Structural Biology Conferences September 24-26, 2018 Berlin, Germany; 12th Bioinformatics Conferences November 26-27, 2018 Dublin, Ireland; 12th Drug Discovery Conferences November 26-27, 2018 Dublin, Ireland; 12th Proteomics Expo November 26-28, 2018 Dublin, Ireland; 12th Molecular Medicine November 26-28, 2018 Dublin, Ireland; 5th Enzymology Conferences February 28-March 01, 2019 Berlin, Germany; Biomanufacturing Strategy Meeting June 11, 2018 Boston, United States; Biostimulants Summit 2018 June 27-28, 2018 Chicago, United States; European Microbiology and Research Conference July 04-06, 2018 Rome, Italy; Molecular Diagnostics July 09-10, 2018; London, UK; 18th International Biotechnology Symposium and Exhibition August 12-17, 2018 Montral, Canada; International Conference On Nanomedicine And Nanobiotechnology September26-28, 2018 Rome, Italy; Marine Biotechnology October 08-12, 2018 Naples, Italy; 2nd International Probiotics, Nutrition & Microbiome Conference October 10-12, 2018 Amsterdam, Netherlands

Related Societies:

Related Biotechnology Conferences | Genetic Engineering Conferences | Pharmaceutical Chemistry Conferences | Biological Engineering Conferences | Bio economy Conferences | Biomedicine Conferences | Microbiology Conferences | Molecular Biology Conferences | Nano-Biotechnology Conferences | Biology Conferences | Embryology Conferences | Pharmacogenomics Conferences

4th Synthetic Biology Conferences October 18-19, 2018 Rome, Italy; 4th Tissue Engineering Conferences; October 18-19, 2018 Rome, Italy; 11th Tissue Engineering Conferences October 18-20, 2018 Rome, Italy; 11th Regenerative Medicine Conferences October 18-20, 2018 at Rome, Italy; 10th Stem Cell Conferences October 08-09, 2018 Zurich, Switzerland; 10th Regenerative Medicine Conferences October 08-09, 2018 Zurich, Switzerland; 9th Cell Conferences March 21-23, 2019 Rome, Italy; 9th Gene Therapy Exhibitions March 21-23, 2019 Rome, Italy; 4th Glycobiology World Congress September 17-19, 2018 Rome, Italy; 13th Metabolomics Conferences October 11-12, 2018 Zurich, Switzerland; 13th Systems Biology Conferences October 11-12, 2018 Zurich, Switzerland; BIO World Congress on Industrial Biotechnology July 16 - 19, 2018 Philadelphia, Pennsylvania; World Biotechnology Conference June 25-27, 2018 Stockholm, Sweden; International Biotechnology and Research Conference April 25-27, 2018 Rome, Italy; 2nd World Congress and Expo on Biotechnology and Bioengineering June 25-27, 2018, Dubai, UAE; BIO Asia International Conference March 5 - 6, 2019 Tokyo, Japan; BIO Patient and Health Advocacy Summit October 25 - 26, 2018 Washington, DC

Related Societies:

Related Societies:

Related Societies:

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Biotech – Scientific American

Monday, October 8th, 2018

Draft guidelines permit gene-editing tools for research into early human development, but would discourage manipulation of embryos for reproduction

5 minutes ago David Cyranoski and Nature magazine

James P. Allison and Tasuku Honjo share the Nobel Prize for their work on harnessing the cancer patient's own immune system to destroy tumors.

October 1, 2018 Steve Mirsky

Researchers at the Mount Sinai Diabetes Center have already developed an artificial pancreas. Next, a drug that could regenerate pancreatic cells in the body.

September 12, 2018

Immunologist James Allison has spent over thirty years studying T cells and developing strategies for cancer immunotherapy. Now, hes looking at new ways to unleash the immune system to eradicate cancer.

September 12, 2018

Interview: Joan Argetsinger Steitz weighs in on #MeToo and working with James Watson

September 11, 2018 Dina Fine Maron

New device gives an amputee the ability to feel the location of his foot

August 9, 2018 Simon Makin

As Ebola outbreaks occur again and again, the scramble for answers and medications is ongoing

August 6, 2018

Shutting down an overactive enzyme could become a general treatment, rather than one solely intended for the few who inherit a mutated Parkinsons gene

August 6, 2018 Emily Willingham

A flurry of recent findings highlighta contentious question in this area

July 16, 2018 Sharon Begley and STAT

A next-generation cochlear implant might allow the hearing-impaired to listen to music and cope with noise

July 16, 2018 Simon Makin

Activating the reward system boosts anti-tumor immunity in mice

July 13, 2018 Esther Landhuis

The controversy over how many genes are contained in the human genome continues to simmer

June 19, 2018 Cassandra Willyard and Nature magazine

The preliminary findings raise questions about one of the ways this tech edits genomes

June 12, 2018 Sharon Begley and STAT

Three patients in Japan will receive the experimental therapy in the next year

May 30, 2018 David Cyranoski and Nature magazine

The swallowable device looks promising in pigs

May 24, 2018 Andrew Joseph and STAT

A new technique could replace the need for human embryos in some lab experiments

May 24, 2018 Sara Reardon and Nature magazine

Racing pigeons is big businessand doping is common. Now scientists have devised a way to detect doping in the avian athletes. Christopher Intagliata reports.

May 15, 2018 Christopher Intagliata

Researchers are intent on decoding body-brain nerve signals to diagnose ailments

May 10, 2018 Tim Hornyak

Chinas move is expected to complement other countriesrelated initiatives

April 6, 2018 David Cyranoski and Nature magazine

Cancerous cells may pick up the characteristics of nearby organs, evading treatment

March 29, 2018 Meghana Keshavan and STAT

Discover world-changing science. Explore our digital archive back to 1845, including articles by more than 150 Nobel Prize winners.

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Degrees in Biotechnology | How to Have a Biotechnology Career

Wednesday, September 19th, 2018

Biotechnology Careers At-a-Glance

The United States leads the pack in biotech revenue, market capitalization, and the number of public biotech companies, according to a 2015 report by Ernst & Young Global Limited. In 2007, three biotechnology companies made more than one billion dollars; by the end of 2014, that number had grown to 26, and there is no end in sight to the massive growth. Biotechnology careers can be found mainly in pharmaceutical companies including Gilead Sciences, Celgene, Biogen, and Regeneron, all companies named by Forbes among the top 10 biotech companies in the country.

People who choose biotech careers have several areas of specialization to choose from. A few options include working as an epidemiologist, microbiologist, biochemist, botany specialist, agricultural and food scientist or biomedical engineer. Graduates might wind up working in a laboratory, creating new seed lines, or in a vast field, testing new soil compositions. They might work to clone animals, develop new pharmaceutical drugs, create a bionic pancreas and so much more. No matter what the career path, it all begins with rigorous study and earning a biotechnology degree.

As with all statistics, salary numbers can be deceiving. There are two reasons why the numbers below should be taken into context.

First, biotechnology careers typically require a bachelors degree for entry, but the field is filled with people who also hold masters and doctoral degrees. For instance, 45 percent of the biomedical engineers who responded to an O*NET survey said a bachelors degree was sufficient; thirty-five percent needed a masters degree and a further 20 percent needed a doctorate. Those with advanced degrees typically have higher earning potential, which partially explains how some biomedical engineers can earn around $50,000 per year while others are clearing $140,000.

Second, there are multiple employers of the scientists listed below. Some of the most prominent are universities, which typically pay less than companies engaged in applied research. Companies make profits, which can be shared with employees; universities do not.

Working in the biotechnology field starts with the proper education. Though there are numerous pathways to the various professions, some steps to success are universal. Heres how to get there.

1

Begin with the right classes

Those interested in biotechnology careers can begin their journey by taking several biology or chemistry electives while in high school. Students should also look into pursuing courses that provide both high school and college credit, such as advanced placement.

2

Start with the bachelors degree

Once high school is over, its time to move into college and earn a bachelors degree in biology, biotechnology (if offered) or a closely related field. Though there are associate degrees in biology that will form a firm foundation for the bachelors, most entry-level positions in biotechnology will require at least a bachelors degree.

3

Get experience

Learning about the job and getting hands-on training in the field can look great on a resume, as well as provide students an opportunity to decide what area of biotechnology interests them the most. Some students choose internships during their college years, while others seek out part-time or full-time work with biotech companies or labs.

4

Pursue graduate studies

In many cases, biotechnology careers will require a graduate degree for advancement. Depending upon the chosen career path, students might need to embark on their masters degree or end up with a PhD in order to do the work they really want to do.

5

Stay up-to-date

Technology is always changing, growing and shifting. Some fields of biotechnology are moving so fast that they can literally change by the week. Thats why it is so important to stay up-to-date by subscribing to industry publications, becoming active in industry associations, keeping in touch with network contacts, and otherwise staying on top of what is happening in the field.

6

Seek out new opportunities in the field

Biotechnology careers offers quite a bit of overlap; for instance, a soil and plant scientist might choose to eventually work as an agricultural and food scientist, and their education might support both paths. Seeking out new opportunities to expand on a current profession is one of the perks of working in the field, and can lead to exciting possibilities.

Those who are interested in biotechnology will discover a dizzying array of possibilities for degrees; anything from the certificate to the PhD can be helpful during the career pursuit. In addition, many biotech degrees easily adapt to online study for students who dont have the ability to attend traditional classes. Heres an overview of which degrees might be more advantageous for certain situations.

I am excited to begin work in biotechnology. I need something that will allow me to get my foot in the door while giving me a strong foundation for graduate work.

I have been working in the field for years, but there are some points that I need to brush up on times have definitely changed these last few years, and Im ready to change with it. But leaving my job to go back to school is simply not an option, as finances would be too tight.

I already have my bachelors degree, but none of my classes focused on the high-level biology I need to know in order to move into the biotech field. I need to get a bit more education while I gain experience.

I definitely want to go into biotech but I have no idea where to begin. I want to test the waters a bit and leave my options open for changing my degree path when I find what I really want to do

I grew up on a farm and love working with animals. I want to be an animal scientist, so I can help make their lives better. Its a journey that will take some serious time and effort, but Im ready for the challenge.

Ive been working in the field for a while, but promotions and pay raises seem rather elusive one manager pointed out that my educational level is holding me back. Its time to remedy that problem.

Choosing the best biotechnology degrees can be tough, as there are so many options out there. However, the desired career path often provides clues to which degree might be best, as well as which level of educational attainment is expected. Heres what students can expect to learn from each.

There are two types of biotechnology certificate programs: Those that are designed for students who have completed their graduate studies and now need more specialized training, or those who have earned their bachelors degree but didnt get all the recommended courses to move into a biotech career. The latter scenario often applies to those who have earned their bachelors in another field but have now chosen a career change to the biotechnology field.

Most certificate programs take a year or less to complete, and are very focused on the particular educational path, with little to no general education courses. Some of the common courses in a certificate program include:

This course helps students understand structural organic chemistry, chemical thermodynamics, acid base chemistry, and reaction mechanisms.

Understanding of Lewis structures

Strategic use of reaction mechanisms

Knowledge of biological molecules and how they form and interact

Students will explore the ethical issues in biotechnology, including real-world case studies and current events in the field.

Applying philosophical theories to critical current issues

Conducting human experimentation in a compassionate and ethical manner

Ethical practices regarding animal testing

This class focuses on the regulatory approval process for drugs, foods, cosmetics and more.

Proper compliance with regulatory rules

Legal implications in regulatory issues

Ethical considerations when bring a new product to market

The associate degree in biotechnology prepares students to eventually move into the bachelors degree program. Though there are some employers who will accept students who have only the associate degree, many entry-level jobs do require the four-year education. The associate degree requires four years of study to complete, though some accelerated programs might allow completion in as little as 18 months. Some common courses found in the associate in biotech program include:

This course serves as an important overview for those who are interested in the biotech field, including a look at career options.

Use of safe laboratory procedures

Understanding the variety of potential careers and how they relate to each other

Applying the basics of biotech to day-to-day life

Students will learn quality assurance principles and how they relate to the biotech fields.

Understanding the differences in regulated and non-regulated work environments

Quality system usage, including Lean and Six Sigma

Theoretical views of quality assurance as applied to real-world events

Focuses on computational biology and bioinformatics as it relates to processes and end results.

Methods for high-volume data collection

Storing and accessing biological data

Use of common programs and algorithms to analyze data

For most careers in biotechnology including that of biomedical engineer, food scientist, microbiologist, plant and soil scientist, and agricultural engineer, among others a bachelors degree is required for entry-level work. The bachelors degree typically takes four years to complete and offers some opportunities for specialization through the use of electives under the biotechnology umbrella. Some classes that students can expect to take include:

Students explore the current research in biological science and analyze it according to biotechnology principles.

Critical analysis of current research

Use of scientific reasoning to make evaluative decisions

Understanding core biological concepts

Focus on the structure and function of cells, with an emphasis on eukaryotic cell biology.

Use molecular biology knowledge to draw research conclusions

Understand DNA replication and repair

The applications of genetic engineering

An in-depth look at safety procedures and proper management of laboratory spaces.

Management of personnel, space, inventory and equipment

Proper communications with stakeholders

Compliance with all safety and health regulations

The masters in biotechnology degree allows students to enhance their knowledge through a specialized curriculum. The masters in biotech is made up of a few core courses, which are then enhanced by electives that focus on the particular educational path a student wants to carve out for themselves. The masters degree takes two to three years to complete, depending upon the program. Many programs are available online, as schools recognize the need for a flexible schedule for those who are already working in the field.

Some courses that can be found at the masters level include:

Focuses on all the aspects of project management, such as working in teams, managing time, structuring projects and more.

Consideration of each phase of a project

Communicating with a wide variety of people involved in a project

Monitoring and controlling change

Students will learn the ins and outs of federal funding and regulations, writing grant proposals, and other sources of funding for research and development.

Students will study how to apply a comprehensive validation philosophy to new ventures in biotech.

Creating equipment or processes that are less prone to failure

Designing robust yet cost-effective projects

Creating validation documents in line with rules and regulations

The doctorate is the pinnacle of the biotechnology field, and offers students quite broad autonomy when choosing an original research project and focus of study. Those who intend to work with in-depth research or move into teaching will need to earn the PhD. Some professions require it, such as that of animal scientist or biophysicist. The doctoral program usually takes between three and four years to complete, though some schools allow up to eight years for completion of the dissertation. Some courses that might be found at the PhD level include:

Students will explore cutting-edge research areas and instruments, with a rotation that takes them through biomedical and biotechnology areas.

Familiarity with the latest technologies

Refresher on how to use instruments that considered out-of-date but might be advantageous for some projects

How to balance research between different laboratories and get the same results using different systems

Students will examine upper-level biotechnology or bio-engineering problems through the lens of equations and statistics.

High-level mathematics literacy

Advanced numerical methods

Refresher on statistical analysis

Students will engage in discussions with leaders in the field on current events and ethical issues that arise from the use of technology in the biological field.

Proper development of biological products

Conducting ethical biomedical research

Marketing and transparency in presenting new biotechnologies to the public

The U.S. biotech industry grew by just about every measure in 2014, according to Ernst and Youngs 2015 industry report. Revenue was up 29 percent, net income increased 293 percent and there were 164 more biotech companies than during the previous year. All of this meant one thing for jobs: There were a lot more of them. The industry added over 10,000 new jobs in 2014, which equates to a staggering 10 percent annual growth rate. Of course, not all of these jobs were for scientists and researchers many were for support staff one might find in any industry. Jobs specific to biotechnology involving research and development and manufacturing are outlined below.

The Bureau of Labor Statistics (BLS) combines three related careers under the heading of agricultural and food scientist: animal scientist, food scientist and technologist, and soil and plant scientist. Although all have the ultimate task of improving farm productivity, they accomplish this in different ways. Each are discussed separately here.

Many people dont think of farming as being sophisticated. Seeds are planted, crops are watered, and eventually food is harvested. But it is an extraordinarily advanced field, and the largest farms are essentially food factories. Engineers are involved in research and development as well as manufacturing. They might oversee water supply and usage, design comfortable areas for the animals, and create machines that can efficiently harvest crops with minimal food loss. Agricultural engineers spend their time both in offices designing systems and on farms testing and applying those systems.

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Global catastrophic risk – Wikipedia

Friday, August 24th, 2018

Hypothetical future event that has the potential to damage human well-being on a global scale

A global catastrophic risk is a hypothetical future event which could damage human well-being on a global scale,[2] even crippling or destroying modern civilization.[3] An event that could cause human extinction or permanently and drastically curtail humanity's potential is known as an existential risk.[4]

Potential global catastrophic risks include anthropogenic risks (technology, governance, climate change) and natural or external risks.[3] Examples of technology risks are hostile artificial intelligence and destructive biotechnology or nanotechnology. Insufficient or malign global governance creates risks in the social and political domain, such as a global war, including nuclear holocaust, bioterrorism using genetically modified organisms, cyberterrorism destroying critical infrastructure like the electrical grid; or the failure to manage a natural pandemic. Problems and risks in the domain of earth system governance include global warming, environmental degradation, including extinction of species, famine as a result of non-equitable resource distribution, human overpopulation, crop failures and non-sustainable agriculture. Examples of non-anthropogenic risks are an asteroid impact event, a supervolcanic eruption, a lethal gamma-ray burst, a geomagnetic storm destroying electronic equipment, natural long-term climate change, or hostile extraterrestrial life.

Philosopher Nick Bostrom classifies risks according to their scope and intensity.[5] A "global catastrophic risk" is any risk that is at least "global" in scope, and is not subjectively "imperceptible" in intensity. Those that are at least "trans-generational" (affecting all future generations) in scope and "terminal"[clarification needed] in intensity are classified as existential risks. While a global catastrophic risk may kill the vast majority of life on earth, humanity could still potentially recover. An existential risk, on the other hand, is one that either destroys humanity (and, presumably, all but the most rudimentary species of non-human lifeforms and/or plant life) entirely or at least prevents any chance of civilization recovering. Bostrom considers existential risks to be far more significant.[6]

Similarly, in Catastrophe: Risk and Response, Richard Posner singles out and groups together events that bring about "utter overthrow or ruin" on a global, rather than a "local or regional" scale. Posner singles out such events as worthy of special attention on cost-benefit grounds because they could directly or indirectly jeopardize the survival of the human race as a whole.[7] Posner's events include meteor impacts, runaway global warming, grey goo, bioterrorism, and particle accelerator accidents.

Researchers experience difficulty in studying near human extinction directly, since humanity has never been destroyed before.[8] While this does not mean that it will not be in the future, it does make modelling existential risks difficult, due in part to survivorship bias.

Bostrom identifies four types of existential risk. "Bangs" are sudden catastrophes, which may be accidental or deliberate. He thinks the most likely sources of bangs are malicious use of nanotechnology, nuclear war, and the possibility that the universe is a simulation that will end. "Crunches" are scenarios in which humanity survives but civilization is irreversibly destroyed. The most likely causes of this, he believes, are exhaustion of natural resources, a stable global government that prevents technological progress, or dysgenic pressures that lower average intelligence. "Shrieks" are undesirable futures. For example, if a single mind enhances its powers by merging with a computer, it could dominate human civilization. Bostrom believes that this scenario is most likely, followed by flawed superintelligence and a repressive totalitarian regime. "Whimpers" are the gradual decline of human civilization or current values. He thinks the most likely cause would be evolution changing moral preference, followed by extraterrestrial invasion.[4]

Some risks, such as that from asteroid impact, with a one-in-a-million chance of causing humanity's extinction in the next century,[9] have had their probabilities predicted using straightforward, well-understood, and (in principle) precise methods (although even in cases like these, the exact rate of large impacts is contested).[10] Similarly, the frequency of volcanic eruptions of sufficient magnitude to cause catastrophic climate change, similar to the Toba Eruption, which may have almost caused the extinction of the human race,[11] has been estimated at about 1 in every 50,000 years.[12]

The relative danger posed by other threats is much more difficult to calculate. In 2008, an informal survey of small but illustrious group of experts on different global catastrophic risks at the Global Catastrophic Risk Conference at the University of Oxford suggested a 19% chance of human extinction by the year 2100. The conference report cautions that the results should be taken "with a grain of salt".[13] In November 2017, a statement by 15,364 scientists from 184 countries indicated that increasing levels of greenhouse gases from use of fossil fuels, human population growth, deforestation, and overuse of land for agricultural production, particularly by farming ruminants for meat consumption, are trending in ways that forecast an increase in human misery over coming decades.[3]

The 2016 annual report by the Global Challenges Foundation estimates that an average American is more than five times more likely to die during a human-extinction event than in a car crash.[14][15]

There are significant methodological challenges in estimating these risks with precision. Most attention has been given to risks to human civilization over the next 100 years, but forecasting for this length of time is difficult. The types of threats posed by nature may prove relatively constant, though new risks could be discovered. Anthropogenic threats, however, are likely to change dramatically with the development of new technology; while volcanoes have been a threat throughout history, nuclear weapons have only been an issue since the 20th century. Historically, the ability of experts to predict the future over these timescales has proved very limited. Man-made threats such as nuclear war or nanotechnology are harder to predict than natural threats, due to the inherent methodological difficulties in the social sciences. In general, it is hard to estimate the magnitude of the risk from this or other dangers, especially as both international relations and technology can change rapidly.

Existential risks pose unique challenges to prediction, even more than other long-term events, because of observation selection effects. Unlike with most events, the failure of a complete extinction event to occur in the past is not evidence against their likelihood in the future, because every world that has experienced such an extinction event has no observers, so regardless of their frequency, no civilization observes existential risks in its history.[8] These anthropic issues can be avoided by looking at evidence that does not have such selection effects, such as asteroid impact craters on the Moon, or directly evaluating the likely impact of new technology.[5]

Some scholars have strongly favored reducing existential risk on the grounds that it greatly benefits future generations. Derek Parfit argues that extinction would be a great loss because our descendants could potentially survive for four billion years before the expansion of the Sun makes the Earth uninhabitable.[16][17] Nick Bostrom argues that there is even greater potential in colonizing space. If future humans colonize space, they may be able to support a very large number of people on other planets, potentially lasting for trillions of years.[6] Therefore, reducing existential risk by even a small amount would have a very significant impact on the expected number of people who will exist in the future.

Exponential discounting might make these future benefits much less significant. However, Gaverick Matheny has argued that such discounting is inappropriate when assessing the value of existential risk reduction.[9]

Some economists have discussed the importance of global catastrophic risks, though not existential risks. Martin Weitzman argues that most of the expected economic damage from climate change may come from the small chance that warming greatly exceeds the mid-range expectations, resulting in catastrophic damage.[18] Richard Posner has argued that we are doing far too little, in general, about small, hard-to-estimate risks of large-scale catastrophes.[19]

Numerous cognitive biases can influence people's judgment of the importance of existential risks, including scope insensitivity, hyperbolic discounting, availability heuristic, the conjunction fallacy, the affect heuristic, and the overconfidence effect.[20]

Scope insensitivity influences how bad people consider the extinction of the human race to be. For example, when people are motivated to donate money to altruistic causes, the quantity they are willing to give does not increase linearly with the magnitude of the issue: people are roughly as concerned about 200,000 birds getting stuck in oil as they are about 2,000.[21] Similarly, people are often more concerned about threats to individuals than to larger groups.[20]

There are economic reasons that can explain why so little effort is going into existential risk reduction. It is a global good, so even if a large nation decreases it, that nation will only enjoy a small fraction of the benefit of doing so. Furthermore, the vast majority of the benefits may be enjoyed by far future generations, and though these quadrillions of future people would in theory perhaps be willing to pay massive sums for existential risk reduction, no mechanism for such a transaction exists.[5]

Some sources of catastrophic risk are natural, such as meteor impacts or supervolcanoes. Some of these have caused mass extinctions in the past.

On the other hand, some risks are man-made, such as global warming,[22] environmental degradation, engineered pandemics and nuclear war. According to the Future of Humanity Institute, human extinction is more likely to result from anthropogenic causes than natural causes.[5][23]

In 2012, Cambridge University created The Cambridge Project for Existential Risk which examines threats to humankind caused by developing technologies.[24] The stated aim is to establish within the University a multidisciplinary research centre, Centre for the Study of Existential Risk, dedicated to the scientific study and mitigation of existential risks of this kind.[24]

The Cambridge Project states that the "greatest threats" to the human species are man-made; they are artificial intelligence, global warming, nuclear war, and rogue biotechnology.[25]

It has been suggested that learning computers that rapidly become superintelligent may take unforeseen actions or that robots would out-compete humanity (one technological singularity scenario).[26] Because of its exceptional scheduling and organizational capability and the range of novel technologies it could develop, it is possible that the first Earth superintelligence to emerge could rapidly become matchless and unrivaled: conceivably it would be able to bring about almost any possible outcome, and be able to foil virtually any attempt that threatened to prevent it achieving its objectives.[27] It could eliminate, wiping out if it chose, any other challenging rival intellects; alternatively it might manipulate or persuade them to change their behavior towards its own interests, or it may merely obstruct their attempts at interference.[27] In Bostrom's book, Superintelligence: Paths, Dangers, Strategies, he defines this as the control problem.[28]

Vernor Vinge has suggested that a moment may come when computers and robots are smarter than humans. He calls this "the Singularity."[29] He suggests that it may be somewhat or possibly very dangerous for humans.[30] This is discussed by a philosophy called Singularitarianism.

Physicist Stephen Hawking, Microsoft founder Bill Gates and SpaceX founder Elon Musk have expressed concerns about the possibility that AI could evolve to the point that humans could not control it, with Hawking theorizing that this could "spell the end of the human race".[31] In 2009, experts attended a conference hosted by the Association for the Advancement of Artificial Intelligence (AAAI) to discuss whether computers and robots might be able to acquire any sort of autonomy, and how much these abilities might pose a threat or hazard. They noted that some robots have acquired various forms of semi-autonomy, including being able to find power sources on their own and being able to independently choose targets to attack with weapons. They also noted that some computer viruses can evade elimination and have achieved "cockroach intelligence." They noted that self-awareness as depicted in science-fiction is probably unlikely, but that there were other potential hazards and pitfalls.[29] Various media sources and scientific groups have noted separate trends in differing areas which might together result in greater robotic functionalities and autonomy, and which pose some inherent concerns.[32][33] Eliezer Yudkowsky believes that risks from artificial intelligence are harder to predict than any other known risks. He also argues that research into artificial intelligence is biased by anthropomorphism. Since people base their judgments of artificial intelligence on their own experience, he claims that they underestimate the potential power of AI. He distinguishes between risks due to technical failure of AI, which means that flawed algorithms prevent the AI from carrying out its intended goals, and philosophical failure, which means that the AI is programmed to realize a flawed ideology.[34]

Biotechnology can pose a global catastrophic risk in the form of bioengineered organisms (viruses, bacteria, fungi, plants or animals). In many cases the organism will be a pathogen of humans, livestock, crops or other organisms we depend upon (e.g. pollinators or gut bacteria). However, any organism able to catastrophically disrupt ecosystem functions, e.g. highly competitive weeds, outcompeting essential crops, poses a biotechnology risk.

A biotechnology catastrophe may be caused by accidentally releasing a genetically engineered organism escaping from controlled environments, by the planned release of such an organism which then turns out to have unforeseen and catastrophic interactions with essential natural or agro-ecosystems, or by intentional usage of biological agents in biological warfare, bioterrorism attacks.[35] Terrorist applications of biotechnology have historically been infrequent.[35] To what extent this is due to a lack of capabilities or motivation is not resolved.[35]

Exponential growth has been observed in the biotechnology sector and Noun and Chyba predict that this will lead to major increases in biotechnological capabilities in the coming decades.[35] They argue that risks from biological warfare and bioterrorism are distinct from nuclear and chemical threats because biological pathogens are easier to mass-produce and their production is hard to control (especially as the technological capabilities are becoming available even to individual users).[35]

Given current development, more risk from novel, engineered pathogens is to be expected in the future.[35] Pathogens may be intentionally or unintentionally genetically modified to change virulence and other characteristics.[35] For example, a group of Australian researchers unintentionally changed characteristics of the mousepox virus while trying to develop a virus to sterilize rodents.[35] The modified virus became highly lethal even in vaccinated and naturally resistant mice.[36][37] The technological means to genetically modify virus characteristics are likely to become more widely available in the future if not properly regulated.[35]

Noun and Chyba propose three categories of measures to reduce risks from biotechnology and natural pandemics: Regulation or prevention of potentially dangerous research, improved recognition of outbreaks and developing facilities to mitigate disease outbreaks (e.g. better and/or more widely distributed vaccines).[35]

(See also Natural pathogens below.)

Cyberattacks have the potential to destroy everything from personal data to electric grids. Christine Peterson, co-founder and past president of the Foresight Institute, believes a cyberattack on electric grids has the potential to be a catastrophic risk.[38] Peterson also identifies attacks on Internet of Things devices as potentially catastrophic.

Global warming refers to the warming caused by human technology since the 19th century or earlier. Global warming reflects abnormal variations to the expected climate within the Earth's atmosphere and subsequent effects on other parts of the Earth. Projections of future climate change suggest further global warming, sea level rise, and an increase in the frequency and severity of some extreme weather events and weather-related disasters. Effects of global warming include loss of biodiversity, stresses to existing food-producing systems, increased spread of known infectious diseases such as malaria, and rapid mutation of microorganisms.

It has been suggested that runaway global warming (runaway climate change) might cause Earth to become searingly hot like Venus. In less extreme scenarios, it could cause the end of civilization as we know it.[39]

An environmental or ecological disaster, such as world crop failure and collapse of ecosystem services, could be induced by the present trends of overpopulation, economic development,[40] and non-sustainable agriculture. An October 2017 report published in The Lancet stated that toxic air, water, soils, and workplaces were collectively responsible for 9 million deaths worldwide in 2015, particularly from air pollution which was linked to deaths by increasing susceptibility to non-infectious diseases, such as heart disease, stroke, and lung cancer.[41] The report warned that the pollution crisis was exceeding "the envelope on the amount of pollution the Earth can carry" and threatens the continuing survival of human societies.[41]

Most environmental scenarios involve one or more of the following: Holocene extinction event,[42] scarcity of water that could lead to approximately one half of the Earth's population being without safe drinking water, pollinator decline, overfishing, massive deforestation, desertification, climate change, or massive water pollution episodes. Detected in the early 21st century, a threat in this direction is colony collapse disorder,[43] a phenomenon that might foreshadow the imminent extinction[44] of the Western honeybee. As the bee plays a vital role in pollination, its extinction would severely disrupt the food chain.

Romanian American economist Nicholas Georgescu-Roegen, a progenitor in economics and the paradigm founder of ecological economics, has argued that the carrying capacity of Earth that is, Earth's capacity to sustain human populations and consumption levels is bound to decrease sometime in the future as Earth's finite stock of mineral resources is presently being extracted and put to use; and consequently, that the world economy as a whole is heading towards an inevitable future collapse, leading to the demise of human civilization itself.[45]:303f Ecological economist and steady-state theorist Herman Daly, a student of Georgescu-Roegen, has propounded the same argument by asserting that "... all we can do is to avoid wasting the limited capacity of creation to support present and future life [on Earth]."[46]:370

Ever since Georgescu-Roegen and Daly published these views, various scholars in the field have been discussing the existential impossibility of distributing Earth's finite stock of mineral resources evenly among an unknown number of present and future generations. This number of generations is likely to remain unknown to us, as there is little way of knowing in advance if or when mankind will eventually face extinction. In effect, any conceivable intertemporal distribution of the stock will inevitably end up with universal economic decline at some future point.[47]:253256 [48]:165 [49]:168171 [50]:150153 [51]:106109 [52]:546549 [53]:142145

Nick Bostrom suggested that in the pursuit of knowledge, humanity might inadvertently create a device that could destroy Earth and the Solar System.[54] Investigations in nuclear and high-energy physics could create unusual conditions with catastrophic consequences. For example, scientists worried that the first nuclear test might ignite the atmosphere.[55][56] More recently, others worried that the RHIC[57] or the Large Hadron Collider might start a chain-reaction global disaster involving black holes, strangelets, or false vacuum states. These particular concerns have been refuted,[58][59][60][61] but the general concern remains.

Biotechnology could lead to the creation of a pandemic, chemical warfare could be taken to an extreme, nanotechnology could lead to grey goo in which out-of-control self-replicating robots consume all living matter on earth while building more of themselvesin both cases, either deliberately or by accident.[62]

Many nanoscale technologies are in development or currently in use.[63] The only one that appears to pose a significant global catastrophic risk is molecular manufacturing, a technique that would make it possible to build complex structures at atomic precision.[64] Molecular manufacturing requires significant advances in nanotechnology, but once achieved could produce highly advanced products at low costs and in large quantities in nanofactories of desktop proportions.[63][64] When nanofactories gain the ability to produce other nanofactories, production may only be limited by relatively abundant factors such as input materials, energy and software.[63]

Molecular manufacturing could be used to cheaply produce, among many other products, highly advanced, durable weapons.[63] Being equipped with compact computers and motors these could be increasingly autonomous and have a large range of capabilities.[63]

Phoenix and Treder classify catastrophic risks posed by nanotechnology into three categories:

At the same time, nanotechnology may be used to alleviate several other global catastrophic risks.[63]

Several researchers state that the bulk of risk from nanotechnology comes from the potential to lead to war, arms races and destructive global government.[36][63][65] Several reasons have been suggested why the availability of nanotech weaponry may with significant likelihood lead to unstable arms races (compared to e.g. nuclear arms races):

Since self-regulation by all state and non-state actors seems hard to achieve,[67] measures to mitigate war-related risks have mainly been proposed in the area of international cooperation.[63][68] International infrastructure may be expanded giving more sovereignty to the international level. This could help coordinate efforts for arms control. International institutions dedicated specifically to nanotechnology (perhaps analogously to the International Atomic Energy Agency IAEA) or general arms control may also be designed.[68] One may also jointly make differential technological progress on defensive technologies, a policy that players should usually favour.[63] The Center for Responsible Nanotechnology also suggests some technical restrictions.[69] Improved transparency regarding technological capabilities may be another important facilitator for arms-control.

A grey goo is another catastrophic scenario, which was proposed by Eric Drexler in his 1986 book Engines of Creation[70] and has been a theme in mainstream media and fiction.[71][72] This scenario involves tiny self-replicating robots that consume the entire biosphere using it as a source of energy and building blocks. Nowadays, however, nanotech expertsincluding Drexlerdiscredit the scenario. According to Chris Phoenix a "so-called grey goo could only be the product of a deliberate and difficult engineering process, not an accident".[73]

The scenarios that have been explored most frequently are nuclear warfare and doomsday devices. Although the probability of a nuclear war per year is slim, Professor Martin Hellman has described it as inevitable in the long run; unless the probability approaches zero, inevitably there will come a day when civilization's luck runs out.[74] During the Cuban missile crisis, U.S. president John F. Kennedy estimated the odds of nuclear war at "somewhere between one out of three and even".[75] The United States and Russia have a combined arsenal of 14,700 nuclear weapons,[76] and there is an estimated total of 15,700 nuclear weapons in existence worldwide.[76]

While popular perception sometimes takes nuclear war as "the end of the world", experts assign low probability to human extinction from nuclear war.[77][78] In 1982, Brian Martin estimated that a USSoviet nuclear exchange might kill 400450 million directly, mostly in the United States, Europe and Russia, and maybe several hundred million more through follow-up consequences in those same areas.[77]

Nuclear war could yield unprecedented human death tolls and habitat destruction. Detonating large numbers of nuclear weapons would have an immediate, short term and long-term effects on the climate, causing cold weather and reduced sunlight and photosynthesis[79] that may generate significant upheaval in advanced civilizations.[80]

Beyond nuclear, other threats to humanity include biological warfare (BW) and bioterrorism. By contrast, chemical warfare, while able to create multiple local catastrophes, is unlikely to create a global one.

The 20th century saw a rapid increase in human population due to medical developments and massive increases in agricultural productivity[81] such as the Green Revolution.[82] Between 1950 and 1984, as the Green Revolution transformed agriculture around the globe, world grain production increased by 250%. The Green Revolution in agriculture helped food production to keep pace with worldwide population growth or actually enabled population growth. The energy for the Green Revolution was provided by fossil fuels in the form of fertilizers (natural gas), pesticides (oil), and hydrocarbon-fueled irrigation.[83] David Pimentel, professor of ecology and agriculture at Cornell University, and Mario Giampietro, senior researcher at the National Research Institute on Food and Nutrition (INRAN), place in their 1994 study Food, Land, Population and the U.S. Economy the maximum U.S. population for a sustainable economy at 200 million. To achieve a sustainable economy and avert disaster, the United States must reduce its population by at least one-third, and world population will have to be reduced by two-thirds, says the study.[84]

The authors of this study believe that the mentioned agricultural crisis will begin to have an effect on the world after 2020, and will become critical after 2050. Geologist Dale Allen Pfeiffer claims that coming decades could see spiraling food prices without relief and massive starvation on a global level such as never experienced before.[85][86]

Wheat is humanity's third-most-produced cereal. Extant fungal infections such as Ug99[87] (a kind of stem rust) can cause 100% crop losses in most modern varieties. Little or no treatment is possible and infection spreads on the wind. Should the world's large grain-producing areas become infected, the ensuing crisis in wheat availability would lead to price spikes and shortages in other food products.[88]

Several asteroids have collided with earth in recent geological history. The Chicxulub asteroid, for example, is theorized to have caused the extinction of the non-avian dinosaurs 66 million years ago at the end of the Cretaceous. No sufficiently large asteroid currently exists in an Earth-crossing orbit; however, a comet of sufficient size to cause human extinction could impact the Earth, though the annual probability may be less than 108.[89] Geoscientist Brian Toon estimates that a 60-mile meteorite would be large enough to "incinerate everybody".[90] Asteroids with around a 1km diameter have impacted the Earth on average once every 500,000 years; these are probably too small to pose an extinction risk, but might kill billions of people.[89][91] Larger asteroids are less common. Small near-Earth asteroids are regularly observed. As of 2013, Spaceguard estimates it has identified 95% of all NEOs over 1km in size.[92]

In 1.4 million years, the star Gliese 710 is expected to start causing an increase in the number of meteoroids in the vicinity of Earth when it passes within 1.1 light-years of the Sun, perturbing the Oort cloud. Dynamic models by Garca-Snchez predict a 5% increase in the rate of impact.[93] Objects perturbed from the Oort cloud take millions of years to reach the inner Solar System.

In April 2018, the B612 Foundation reported "It's a 100 per cent certain we'll be hit [by a devastating asteroid], but we're not 100 per cent sure when."[94][95] In June 2018, the US National Science and Technology Council warned that America is unprepared for an asteroid impact event, and has developed and released the "National Near-Earth Object Preparedness Strategy Action Plan" to better prepare.[96][97][98][99][100]

Extraterrestrial life could invade Earth[101] either to exterminate and supplant human life, enslave it under a colonial system, steal the planet's resources, or destroy the planet altogether.

Although evidence of alien life has never been documented, scientists such as Carl Sagan have postulated that the existence of extraterrestrial life is very likely. In 1969, the "Extra-Terrestrial Exposure Law" was added to the United States Code of Federal Regulations (Title 14, Section 1211) in response to the possibility of biological contamination resulting from the U.S. Apollo Space Program. It was removed in 1991.[102] Scientists consider such a scenario technically possible, but unlikely.[103]

An article in The New York Times discussed the possible threats for humanity of intentionally sending messages aimed at extraterrestrial life into the cosmos in the context of the SETI efforts. Several renowned public figures such as Stephen Hawking and Elon Musk have argued against sending such messages on the grounds that extraterrestrial civilizations with technology are probably far more advanced than humanity and could pose an existential threat to humanity.[104]

Climate change refers to a lasting change in the Earth's climate. The climate has ranged from ice ages to warmer periods when palm trees grew in Antarctica. It has been hypothesized that there was also a period called "snowball Earth" when all the oceans were covered in a layer of ice. These global climatic changes occurred slowly, prior to the rise of human civilization about 10 thousand years ago near the end of the last Major Ice Age when the climate became more stable. However, abrupt climate change on the decade time scale has occurred regionally. Since civilization originated during a period of stable climate, a natural variation into a new climate regime (colder or hotter) could pose a threat to civilization.

In the history of the Earth, many ice ages are known to have occurred. More ice ages will be possible at an interval of 40,000100,000 years. An ice age would have a serious impact on civilization because vast areas of land (mainly in North America, Europe, and Asia) could become uninhabitable. It would still be possible to live in the tropical regions, but with possible loss of humidity and water. Currently, the world is in an interglacial period within a much older glacial event. The last glacial expansion ended about 10,000 years ago, and all civilizations evolved later than this. Scientists do not predict that a natural ice age will occur anytime soon. This may be due to manmade emissions potentially delaying the possible onset or another ice age for at least another 50,000 years.

A number of astronomical threats have been identified. Massive objects, e.g. a star, large planet or black hole, could be catastrophic if a close encounter occurred in the Solar System. In April 2008, it was announced that two simulations of long-term planetary movement, one at the Paris Observatory and the other at the University of California, Santa Cruz, indicate a 1% chance that Mercury's orbit could be made unstable by Jupiter's gravitational pull sometime during the lifespan of the Sun. Were this to happen, the simulations suggest a collision with Earth could be one of four possible outcomes (the others being Mercury colliding with the Sun, colliding with Venus, or being ejected from the Solar System altogether). If Mercury were to collide with Earth, all life on Earth could be obliterated entirely: an asteroid 15km wide is believed to have caused the extinction of the non-avian dinosaurs, whereas Mercury is 4,879km in diameter.[105]

Another cosmic threat is a gamma-ray burst, typically produced by a supernova when a star collapses inward on itself and then "bounces" outward in a massive explosion. Under certain circumstances, these events are thought to produce massive bursts of gamma radiation emanating outward from the axis of rotation of the star. If such an event were to occur oriented towards the Earth, the massive amounts of gamma radiation could significantly affect the Earth's atmosphere and pose an existential threat to all life. Such a gamma-ray burst may have been the cause of the OrdovicianSilurian extinction events. Neither this scenario nor the destabilization of Mercury's orbit are likely in the foreseeable future.[106]

If the Solar System were to pass through a dark nebula, a cloud of cosmic dust, severe global climate change would occur.[107]

A powerful solar flare or solar superstorm, which is a drastic and unusual decrease or increase in the Sun's power output, could have severe consequences for life on Earth.

If our universe lies within a false vacuum, a bubble of lower-energy vacuum could come to exist by chance or otherwise in our universe, and catalyze the conversion of our universe to a lower energy state in a volume expanding at nearly the speed of light, destroying all that we know without forewarning.[108][further explanation needed] Such an occurrence is called vacuum decay.

The magnetic poles of the Earth shifted many times in geologic history. The duration of such a shift is still debated. Theories exist that during such times, the Earth's magnetic field would be substantially weakened, threatening civilization by allowing radiation from the Sun, especially solar wind, solar flares or cosmic radiation, to reach the surface. These theories have been somewhat discredited, as statistical analysis shows no evidence for a correlation between past reversals and past extinctions.[109][110]

Numerous historical examples of pandemics[111] had a devastating effect on a large number of people. The present, unprecedented scale and speed of human movement make it more difficult than ever to contain an epidemic through local quarantines. A global pandemic has become a realistic threat to human civilization.

Naturally evolving pathogens will ultimately develop an upper limit to their virulence.[112] Pathogens with the highest virulence, quickly killing their hosts reduce their chances of spread the infection to new hosts or carriers.[113] This simple model predicts that - if virulence and transmission are not genetically linked - pathogens will evolve towards low virulence and rapid transmission. However, this is not necessarily a safeguard against a global catastrophe, for the following reasons:

1. The fitness advantage of limited virulence is primarily a function of a limited number of hosts. Any pathogen with a high virulence, high transmission rate and long incubation time may have already caused a catastrophic pandemic before ultimately virulence is limited through natural selection.2. In models where virulence level and rate of transmission are related, high levels of virulence can evolve.[114] Virulence is instead limited by the existence of complex populations of hosts with different susceptibilities to infection, or by some hosts being geographically isolated.[112] The size of the host population and competition between different strains of pathogens can also alter virulence.[115] 3. A pathogen that infects humans as a secondary host and primarily infects another species (a zoonosis) has no constraints on its virulence in people, since the accidental secondary infections do not affect its evolution.[116]

Naturally evolving organisms, like the products of biotechnology, can disrupt essential ecosystem functions.

An example of a pathogen able to threaten global food security is the wheat rust Ug99.

Other examples are neobiota (invasive species), i.e. organisms that become disruptive to ecosystems once transportedoften as a result of human activityto a new geographical region. Normally the risk is a local disruption. If it becomes coupled with serious crop failures and a global famine it may, however, pose a global catastrophic risk.

A remote possibility is a megatsunami. It has been suggested that a megatsunami caused by the collapse of a volcanic island could, for example, destroy the entire East Coast of the United States, but such predictions are based on incorrect assumptions and the likelihood of this happening has been greatly exaggerated in the media.[117] While none of these scenarios are likely to destroy humanity completely, they could regionally threaten civilization. There have been two recent high-fatality tsunamisafter the 2011 Thoku earthquake and the 2004 Indian Ocean earthquake. A megatsunami could have astronomical origins as well, such as an asteroid impact in an ocean.[118]

A geological event such as massive flood basalt, volcanism, or the eruption of a supervolcano[119] could lead to a so-called volcanic winter, similar to a nuclear winter. One such event, the Toba eruption,[120] occurred in Indonesia about 71,500 years ago. According to the Toba catastrophe theory,[121] the event may have reduced human populations to only a few tens of thousands of individuals. Yellowstone Caldera is another such supervolcano, having undergone 142 or more caldera-forming eruptions in the past 17 million years.[122]A massive volcano eruption would eject extraordinary volumes of volcanic dust, toxic and greenhouse gases into the atmosphere with serious effects on global climate (towards extreme global cooling: volcanic winter if short-term, and ice age if long-term) or global warming (if greenhouse gases were to prevail).

When the supervolcano at Yellowstone last erupted 640,000 years ago, the thinnest layers of the ash ejected from the caldera spread over most of the United States west of the Mississippi River and part of northeastern Mexico. The magma covered much of what is now Yellowstone National Park and extended beyond, covering much of the ground from Yellowstone River in the east to the Idaho falls in the west, with some of the flows extending north beyond Mammoth Springs.[123]

According to a recent study, if the Yellowstone caldera erupted again as a supervolcano, an ash layer one to three millimeters thick could be deposited as far away as New York, enough to "reduce traction on roads and runways, short out electrical transformers and cause respiratory problems". There would be centimeters of thickness over much of the U.S. Midwest, enough to disrupt crops and livestock, especially if it happened at a critical time in the growing season. The worst-affected city would likely be Billings, Montana, population 109,000, which the model predicted would be covered with ash estimated as 1.03 to 1.8 meters thick.[124]

The main long-term effect is through global climate change, which reduces the temperature globally by about 515 degrees C for a decade, together with the direct effects of the deposits of ash on their crops. A large supervolcano like Toba would deposit one or two meters thickness of ash over an area of several million square kilometers.(1000 cubic kilometers is equivalent to a one-meter thickness of ash spread over a million square kilometers). If that happened in some densely populated agricultural area, such as India, it could destroy one or two seasons of crops for two billion people.[125]

However, Yellowstone shows no signs of a supereruption at present, and it is not certain that a future supereruption will occur there.[126][127]

Research published in 2011 finds evidence that massive volcanic eruptions caused massive coal combustion, supporting models for significant generation of greenhouse gases. Researchers have suggested that massive volcanic eruptions through coal beds in Siberia would generate significant greenhouse gases and cause a runaway greenhouse effect.[128] Massive eruptions can also throw enough pyroclastic debris and other material into the atmosphere to partially block out the sun and cause a volcanic winter, as happened on a smaller scale in 1816 following the eruption of Mount Tambora, the so-called Year Without a Summer. Such an eruption might cause the immediate deaths of millions of people several hundred miles from the eruption, and perhaps billions of deaths[129] worldwide, due to the failure of the monsoon[citation needed], resulting in major crop failures causing starvation on a profound scale.[129]

A much more speculative concept is the verneshot: a hypothetical volcanic eruption caused by the buildup of gas deep underneath a craton. Such an event may be forceful enough to launch an extreme amount of material from the crust and mantle into a sub-orbital trajectory.

Planetary management and respecting planetary boundaries have been proposed as approaches to preventing ecological catastrophes. Within the scope of these approaches, the field of geoengineering encompasses the deliberate large-scale engineering and manipulation of the planetary environment to combat or counteract anthropogenic changes in atmospheric chemistry. Space colonization is a proposed alternative to improve the odds of surviving an extinction scenario.[130] Solutions of this scope may require megascale engineering.Food storage has been proposed globally, but the monetary cost would be high. Furthermore, it would likely contribute to the current millions of deaths per year due to malnutrition.[citation needed]

Some survivalists stock survival retreats with multiple-year food supplies.

The Svalbard Global Seed Vault is buried 400 feet (120m) inside a mountain on an island in the Arctic. It is designed to hold 2.5 billion seeds from more than 100 countries as a precaution to preserve the world's crops. The surrounding rock is 6C (21F) (as of 2015) but the vault is kept at 18C (0F) by refrigerators powered by locally sourced coal.[131][132]

More speculatively, if society continues to function and if the biosphere remains habitable, calorie needs for the present human population might in theory be met during an extended absence of sunlight, given sufficient advance planning. Conjectured solutions include growing mushrooms on the dead plant biomass left in the wake of the catastrophe, converting cellulose to sugar, or feeding natural gas to methane-digesting bacteria.[133][134]

Insufficient global governance creates risks in the social and political domain, but the governance mechanisms develop more slowly than technological and social change. There are concerns from governments, the private sector, as well as the general public about the lack of governance mechanisms to efficiently deal with risks, negotiate and adjudicate between diverse and conflicting interests. This is further underlined by an understanding of the interconnectedness of global systemic risks.[135]

The Bulletin of the Atomic Scientists (est. 1945) is one of the oldest global risk organizations, founded after the public became alarmed by the potential of atomic warfare in the aftermath of WWII. It studies risks associated with nuclear war and energy and famously maintains the Doomsday Clock established in 1947. The Foresight Institute (est. 1986) examines the risks of nanotechnology and its benefits. It was one of the earliest organizations to study the unintended consequences of otherwise harmless technology gone haywire at a global scale. It was founded by K. Eric Drexler who postulated "grey goo".[136][137]

Beginning after 2000, a growing number of scientists, philosophers and tech billionaires created organizations devoted to studying global risks both inside and outside of academia.[138]

Independent non-governmental organizations (NGOs) include the Machine Intelligence Research Institute (est. 2000) which aims to reduce the risk of a catastrophe caused by artificial intelligence and the Singularity.[139] The top donors include Peter Thiel and Jed McCaleb.[140] The Lifeboat Foundation (est. 2009) funds research into preventing a technological catastrophe.[141] Most of the research money funds projects at universities.[142] The Global Catastrophic Risk Institute (est. 2011) is a think tank for all things catastrophic risk. It is funded by the NGO Social and Environmental Entrepreneurs. The Global Challenges Foundation (est. 2012), based in Stockholm and founded by Laszlo Szombatfalvy, releases a yearly report on the state of global risks.[14][15] The Future of Life Institute (est. 2014) aims to support research and initiatives for safeguarding life considering new technologies and challenges facing humanity.[143] Elon Musk is one of its biggest donors.[144] The Nuclear Threat Initiative seeks to reduce global threats from nuclear, biological and chemical threats, and containment of damage after an event.[145] It maintains a nuclear material security index.[146]

University-based organizations include the Future of Humanity Institute (est. 2005) which researches the questions of humanity's long-term future, particularly existential risk. It was founded by Nick Bostrom and is based at Oxford University. The Centre for the Study of Existential Risk (est. 2012) is a Cambridge-based organization which studies four major technological risks: artificial intelligence, biotechnology, global warming and warfare. All are man-made risks, as Huw Price explained to the AFP news agency, "It seems a reasonable prediction that some time in this or the next century intelligence will escape from the constraints of biology". He added that when this happens "we're no longer the smartest things around," and will risk being at the mercy of "machines that are not malicious, but machines whose interests don't include us."[147] Stephen Hawking was an acting adviser. The Millennium Alliance for Humanity and the Biosphere is a Stanford University-based organization focusing on many issues related to global catastrophe by bringing together members of academic in the humanities.[148][149] It was founded by Paul Ehrlich among others.[150] Stanford University also has the Center for International Security and Cooperation focusing on political cooperation to reduce global catastrophic risk.[151]

Other risk assessment groups are based in or are part of governmental organizations. The World Health Organization (WHO) includes a division called the Global Alert and Response (GAR) which monitors and responds to global epidemic crisis.[152] GAR helps member states with training and coordination of response to epidemics.[153] The United States Agency for International Development (USAID) has its Emerging Pandemic Threats Program which aims to prevent and contain naturally generated pandemics at their source.[154] The Lawrence Livermore National Laboratory has a division called the Global Security Principal Directorate which researches on behalf of the government issues such as bio-security, counter-terrorism, etc.[155]

Excerpt from:
Global catastrophic risk - Wikipedia

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Biotechnology – NCEA Biology

Wednesday, August 22nd, 2018

91607Demonstrate understanding of human manipulations of genetic transfer and its biological implicationsIntroduction to the standard and key words listA super amazing (it really is) place to start.This assessment could be run as a research task by your teachers so the content will only be provided to understand the concepts around the standard. The main idea is that you will be looking at two biological manipulations (that's something that us humans have done directly to a genome of an animal or plant) and linking this to multiple implications for THAT organism. Remember this standard is not about the human implications and only how it affects the organism or populations. Make sure you build a good understanding as whatever you do will have to be from your own perspective/ words. The big idea for 91607 is on how humans are potentially impacting on and changing the rate and direction of the evolution of populations so make sure you focus on this during your research/ classroom learning.You will need to know about the following topics before doing your assessment. Down the bottom of the page many of these are covered.

As biological knowledge and techniques have developed the actual processes used change. When you are researching you have to try to sort out what techniques have been used in the past and what are being used now. Usually the longer a process has been used the more automated it becomes. Another change, for example, is that when the sequence of a gene becomes known the gene can be produced rather than isolated from the genes in an organism.

When researching on the internet it is important to look at the age of the info you are reading.....one way is to use the dates of any material being referenced and a second is to look at the last date the info was updated. eg look at this site which contains good basic info about how the processes used to be carried out Transgenic cropsLook at the dates of referenced material - 1997, 1998, 1999, and last updated says "March 11, 2004"(from studyit.org ST5)

term

Link to information covering this

annealing

How PCR Works

An animation of the process.

blunt ends

cloning

Animation

Early experiments

Animation

DNA profiling

DNA Applications Choose "Recovering the Romanovs" from the bottom of this page

Fish http://www.thefishsite.com/articles/336/fish-fingerprints-dna-screening-tracks-and-monitors-offenders

DNA sequencing

gel electrophoresis

Link to interactive gel - awesome, unplug your headphones!

gene cloning

Animation

genetic engineering

Genetic engineering, also calledgenetic modification, is the direct manipulation of an organism's genome using biotechnology

GMO

A good online interactive quiz

ligase enzyme

microsatellite

Interesting powerpoint

plasmid

PCR

Another one

The purpose of PCR is to amplify a small amount of DNA into a huge amount of DNA so it can be used in techniques such as gel electrophoresis.

primer

Work through this

recognition site

recombinant DNA

restriction enzyme

extracting DNA

Workshop

Marker assisted selection

A good website.There is a growing arsenal of molecular markers (polymorphisms) that aid in identifying QTL and selecting them for crop and animal enhancement. The process of using such markers is called marker-assisted selection (MAS), which differs from genetic modification because the genes being selected for crop or animal improvement are not altered in any way.

Once you have worked out the manipulation your animals go through for your 2 topics you will have to research the effect of these changed on the gene pools and evolution of the organisms. Remember that with natural selection it happens on POPULATIONS and not individuals. Individuals need to reproduce and then survive in theirhabitatto reproduce or else their alleles will be removed from the population. What implications with this in mind has the genetic manipulation caused? The term 'biological implications' means the biological consequences or changes that are caused or could be caused by the manipulation you are studying. The list of implications you are given is written in broad terms that are often linked together but the terms give you a good starting point for your research. Each different manipulation and species studied has different implications. Remember to look for both positive and negative implications.(From Studyit.org.nz)

All the examples below may not be isolated case but be linked. Forexample (in brief), Bt cotton has been genetically engineered to include a genethat is toxic to bollworm, a parasite that kills the cotton plant. This removes the need for chemical sprays onBt cotton crops. This modificationincreases the survival of individualsand the population in relation to bollworm, so crop size increases but,because it is a monoculture, Bt cotton has reduced genetic biodiversity and a limited gene pool. This means that if the organism issusceptible to another disease or parasite, the whole population is susceptibleso affects the survival of thepopulation as a whole where other risks are concerned. The absence of chemical sprays increases theoccurrence of other non-target pests, which in turn not only damage cotton butalso other crops, affecting the ecosystem.

eg plant species with low genetic diversity (eg wheat) are more likely to all suffer from the same disease. eg populations a transgenic plant species such as Bt-corn have increased survival due to resistance to certain pest insects. (From Studyit.org.nz)

PowerPoint looking at how populations survive.

Plant species with low genetic diversity (eg wheat) are less likely to under go evolution because the population has more fixed alleles so when the environment changes the population has less opportunity to change allele frequency.

Some excellent places to start your research

http://www.biotechlearn.org.nz/ The Biotechnology Learning Hub provides teaching resources for primary and secondary schools.

https://blogs.otago.ac.nz/ouassa/category/resources/biology-resources/ Another great website run by the University of Otago.

The three principal methods used for the creation of transgenic animals are DNA microinjection, embryonic stem cell-mediated gene transfer and retrovirus-mediated gene transfer.a) DNA microinjection.

This method involves the direct microinjection of a chosen gene construct (a single gene or a combination of genes) from another member of the same species or from a different species, into the pronucleus of a fertilized ovum. It is one of the first methods that proved to be effective in mammals (Gordon and Ruddle, 1981). The introduced DNA may lead to the over- or under-expression of certain genes or to the expression of genes entirely new to the animal species. The insertion of DNA is, however, a random process, and there is a high probability that the introduced gene will not insert itself into a site on the host DNA that will permit its expression. The manipulated fertilized ovum is transferred into the oviduct of a recipient female, or foster mother that has been induced to act as a recipient by mating with a vasectomized male.

A major advantage of this method is its applicability to a wide variety of species.b) Embryonic stem cell-mediated gene transfer.

This method involves prior insertion of the desired DNA sequence by homologous recombination into an in vitro culture of embryonic stem (ES) cells. Stem cells are undifferentiated cells that have the potential to differentiate into any type of cell (somatic and germ cells) and therefore to give rise to a complete organism. These cells are then incorporated into an embryo at the blastocyst stage of development. The result is a chimeric animal. ES cell-mediated gene transfer is the method of choice for gene inactivation, the so-called knock-out method.

This technique is of particular importance for the study of the genetic control of developmental processes. This technique works particularly well in mice. It has the advantage of allowing precise targeting of defined mutations in the gene via homologous recombination.c) Retrovirus-mediated gene transfer.

To increase the probability of expression, gene transfer is mediated by means of a carrier or vector, generally a virus or a plasmid. Retroviruses are commonly used as vectors to transfer genetic material into the cell, taking advantage of their ability to infect host cells in this way. Offspring derived from this method are chimeric, i.e., not all cells carry the retrovirus. Transmission of the transgene is possible only if the retrovirus integrates into some of the germ cells.

For any of these techniques the success rate in terms of live birth of animals containing the transgene is extremely low. Providing that the genetic manipulation does not lead to abortion, the result is a first generation (F1) of animals that need to be tested for the expression of the transgene. Depending on the technique used, the F1 generation may result in chimeras. When the transgene has integrated into the germ cells, the so-called germ line chimeras are then inbred for 10 to 20 generations until homozygous transgenic animals are obtained and the transgene is present in every cell. At this stage embryos carrying the transgene can be frozen and stored for subsequent implantation.

Biological implications may involve the impact on: For this part look at Animal and Plant/ Evolution sections

ecosystems

genetic biodiversity

health or survival of individuals

survival of populations

evolution of populations.

And finally the PCR SONG!! Should be a number 1 download on itunes... or not.

Some examples that may be used - there are many more and some have much more usable information than others.

Selective Breeding

Transgenesis

Horses

Golden rice

Corn

Whiffy wheat

Dogs

Daisys modified milk

Apples

GLO fish

Sheep

"Fish tomato"

Achievement

Merit

Excellence

Demonstrate understanding by using biological ideas to describe:

two human manipulations of genetic transfer

two biological implications for each human manipulation of genetic transfer.

As for Achieved and,

Demonstrate in-depth understanding by using biological ideas to explain how or why:

genetic transfer is manipulated for each human manipulation context

and

explain two biological implications within or between the two human manipulation contexts of genetic transfer.

As for Merit and,

Demonstrate comprehensive understanding by:

linking biological ideas within or between human manipulations of genetic transfer

and

two biological implications

The linking of ideas may involve justifying, relating, evaluating, comparing and contrasting, and analysing.

it could be linking 'one implication with another'. Forming links means putting ideas together to explain something eg how whole organism cloning, of an animal used for food, could result in a specific problem (eg reduced genetic diversity) for humans in the future and what the implication of this problem could be (eg reduced survival leading to reduced food supply).

For your Biotech project a possible format could be (please note this may or may not berelevantto the way your teacher has runyour internal) - please talk to them first..

Intro - Introduction to what genetic manipulation is including a brief description of focus manipulations of manupulation 1 and 2.

P1 - Introduce case study for 1.

P2 - Biological processes of 1 in relation to your case study (e.g. selection, inbreeding and marker assisted selection for selective breeding though your topic may be different)

P3 - Biological implications of selective breeding of your case study (e.g. at least 2 of; ecosystems, genetic biodiversity, health or survival of individuals, survival of populations or evolution of populations)

P4 - Introduce case study for 2.

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Biotechnology - NCEA Biology

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Biotechnology | University of Canterbury

Wednesday, August 22nd, 2018

Qualifications Overview

Biotechnology is of national and international importance. It considers and develops knowledge about biochemical, molecular, ecological, and evolutionary processes. Biotechnology tools are applied in research underpinning biodiversity and biosecurity throughout Aotearoa NewZealand.

Biotechnology research is directed towards developing technology with both economic and environmental outcomes. The OECD has predicted that, by 2030, biotechnology will assume a major role in the global economy with the advances from research in the tertiary sector.

The School of Biological Sciences | Te Kura Ptaiao Koiora offers the Bachelor of Science endorsed in Biotechnology to students majoring in Biological Sciences. Students follow one of two pathways:

Year 13 biology, statistics, and chemistry is strongly recommended.

For certain disciplines, some knowledge of physics is helpful.

All students should have adequate English skills.

As an emerging field with both national and international importance, biotechnology provides many career opportunities in universities, business, government agencies, Crown Research Institutes, and in ministries concerned with the environment, agriculture, and forestry.

Find out more about what you can do with a degree in Biotechnology.

'Biology at Canterbury is great, and Biotechnology is a very employable, fast-growing and lucrative ...

Anish Shah

Biological Sciences, Biotechnology

'My dream is to be involved in as many ventures as I can, specialising in clean energies...'

Steve Rowe

Biotechnology, Strategy and Entrepreneurship

School of Biological Sciences | Te Kura Ptaiao Koiora

Phone +64 3 369 5200 Email biological-sciences@canterbury.ac.nz

Location See the School's website for up-to-date location details.

Postal address College of Science | Te Rngai PtaiaoUniversity of Canterbury | Te Whare Wnanga o Waitaha Private Bag 4800 Christchurch 8140 New Zealand

Choose an area that you are interested in and learn how UC's extensive range of study options can let you study what you want to.

Biology means the study of living things. Biologists investigate animals, plants, and microbes in many different ways and on a huge range of scales from ...

Chemistry is the central science. It deals with the composition, structure, and behaviour of the atoms and molecules that make up all forms of matter. ...

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Biotechnology | University of Canterbury

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Biotechnology and biological sciences | University of Canterbury

Wednesday, August 22nd, 2018

UC's School of Biological Sciences is a vibrant research environment, which receives more than $3 million of external research income every year.

Research is fascinating and conducted across three main fields - biotechnology, biodiversity and biosecurity, all of which are exciting and rapidly developing subjects worldwide.

Our students mix and match, according to their needs and interests, from the diverse range of courses including Antarctic ecosystems, marine ecology and climate change. There are opportunities to use gene technologies, electron microscopes and satellite images, and the research can take you to field stations throughout New Zealand's South Island, to Antarctica and the other side of the world.

Areas of current research biomolecular interactionsinclude:

Biomolecular Interaction Centre

Staff actively working in these areas are:

Areas of current research in biosafety include:

Areas of current research in biomedicine include:

Staff actively working in these areas are:

Areas of current research in bioengineering include:

Staff actively working in these areas are:

Areas of current research in Antarctic studies include:

Staff actively working in these areas are:

Areas of current research in atmospheric processes include:

Staff actively working in these areas are:

Areas of current research in aquaculture and marine ecology include:

Staff actively working in these areas are:

Areas of current research in climate change include:

Staff actively working in these areas are:

Areas of current research in free radical biochemistry include:

Staff actively working in these areas are:

Areas of current research in freshwater ecology and management include:

Staff actively working in these areas are:

Areas of current research in plant processes include:

Staff actively working in these areas are:

Continued here:
Biotechnology and biological sciences | University of Canterbury

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NZTech and NZBio combine tech forces – BIOTechNZ

Wednesday, August 22nd, 2018

04Jul

New Zealand is beginning to witness unprecedented opportunities in areas of technology convergence as cutting-edge and world-first technology continues to accelerate and merge.

NZTech chief executive Graeme Muller says New Zealand has a history of innovation in the biotech and biosciences areas, often driven by strong Kiwi foundations in the primary sectors.

So, it is no surprise NZBio is merging with the NZTech Alliance of 18 tech sector areas.

We have seen biotech companies like Comvita merging their knowledge of a natural product like honey with biotech to create world-leading honey-based medicinal products, Muller says.

We have also seen New Zealand-founded carbon recycling company Lanzatech merging biotech with manufacturing.

As biotechnology, high-tech manufacturing and ICT such as artificial intelligence begin to cross over, the New Zealand tech ecosystem is now well placed to identify and support future growth companies through this coming together of NZBio and NZTech.

At the heart of this amazing period in human history is the convergence of atoms, bits and genes, the ability to use technology to do amazing things like New Zealands Revolution Fibres which is using electrospinning to produce collagen nanofibres and create artificial skin.

NZBio chief executive Dr Zahra Champion says merging with NZTech was a natural fit.

In todays world, the importance of biotech is increased in many fields, from medicines to agriculture, from animal husbandry to textiles, from defenceless to energetic, Dr Champion says.

New Zealand is fragmented across all sectors with large number of industry bodies across all sectors. We are seeing the blurring of the lines between bioscience and technology.

Biotech is everything bio-based such as bioscience, biochemistry, biotechnology, biomanufacturing and life sciences within the agritech, health diagnostics and therapeutics, industrial, environmental and foodtech sectors.

Dr Champion says the industry brings with it high-paying jobs and innovative ideas in an industry that encompasses a huge diversity of applications and being part of the NZTech Alliance, will enable us to maximise New Zealands bio-base technology capability to create a strong and prosperous New Zealand bio economy.

More than 70 percent of New Zealands export earnings are derived from biology-based industries spanning human and animal health, agriculture, horticulture and other natural products. Exports include finished products and ingredients destined for the food, cosmetics, nutraceutical and pharmaceutical industries.

The OECD has estimated the potential contribution of the bio-economy to New Zealands GDPWill climb to $NZ182 billion by 2030.

For further information contact Make Lemonade editor-in-chief Kip Brook on 0275 030188.

Photo: Zahra Champion

Originally posted here:
NZTech and NZBio combine tech forces - BIOTechNZ

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Biotech, life sciences & pharmaceuticals – AJ Park

Wednesday, August 22nd, 2018

Biotech, life science and pharmaceutical innovations are at the cutting edge of technology and research and development. The risks and challenges are huge, but so are the potential rewards.

The complexity of biotechnology, life sciences and pharmaceutical patents means that you need access to a team of highly specialised advisors. And when you need to protect and exploit your biotech, life sciences and pharmaceutical innovations, its essential you are advised by a team that has a thorough understanding of the technology as well as the business issues facing the international industry.

AJ Park has a dedicated team of experts who specialise in biotechnology, life sciences and pharmaceuticals. Our specialist team of patent attorneys includes many with dual science and law qualifications, and several with PhDs. Some have benefited from industry experience or research tenures at universities throughout the world, and others have trained as intellectual property office examiners.

Our team works with a range of entities involved in biotech, life sciences and pharmaceuticals. Our clients include start-up companies, food technology companies, life sciences companies, multi-national pharmaceutical companies, Crown Research Institutes and universities.

We are a committed sponsor of the New Zealand biotechnology industry body NZBio, and a member of the Australian equivalent AusBiotech, which gives us the opportunity to work with many of Australasias most innovative biotech companies.

Our investment in keeping up-to-date with international developments in biotech, life sciences and pharmaceuticals means you can be confident that the advice we give you is world-class.

Although the technology and processes can be complex, we will communicate clearly and make sure you understand what you need to know.

For plain English advice on biotech, life sciences and pharmaceutical inventions, get in touch with one of our experts below.

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Biotech, life sciences & pharmaceuticals - AJ Park

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Biotechnology Definition | Investopedia

Monday, August 13th, 2018

What is 'Biotechnology'

Biotechnology is the use of living organisms to make products or run processes. Biotechnology is best known for its huge role in the field of medicine, and is also used in other areas such as food and fuel.

Biotechnology involves understanding how living organisms function at the molecular level, so it combines a number of disciplines including biology, physics, chemistry, mathematics, science and technology. Modern biotechnology continues to make very significant contributions to extending the human lifespan and improving the quality of life through numerous ways, including providing products and therapies to combat diseases, generating higher crop yields, and using biofuels to reduce greenhouse gas emissions. Hungarian engineer Karl Ereky reportedly coined the term biotechnology, which is often referred to as biotech, in 1919.

Biotechnology in its basic form has existed for thousands of years, dating back to an era when humans first learned to produce bread, beer and wine using the natural process of fermentation. For centuries, the principles of biotechnology were restricted to agriculture, such as harvesting better crops and improving yields by using the best seeds, and breeding livestock.

The field of biotechnology began to develop rapidly from the 19thcentury, with the discovery of microorganisms, Gregor Mendels study of genetics, and ground-breaking work on fermentation and microbial processes by giants in the field such as Pasteur and Lister. Early 20thcentury biotechnology led to the major discovery by Alexander Fleming of penicillin, which went into large-scale production in the 1940s.

Biotechnology took off from the 1950s, spurred by a better understanding in the post-war period of cell function and molecular biology. Every decade since then produced major breakthroughs in biotechnology. These include the discovery of the 3D structure of DNA in the '50s; insulin synthesis and the development of vaccines for measles, mumps and rubella in the '60s; massive strides in DNA research in the '70s; the development of the first biotech-derived drugs and vaccines to treat diseases such as cancer and hepatitis B in the '80s; the identification of numerous genes and the introduction of new treatments in decades for managing multiple sclerosis and cystic fibrosis in the '90s; and the completion of the human genome sequence in the '90s, which made it possible for scientists worldwide to research new treatments for diseases with genetic origins like cancer, heart disease, and Alzheimers.

The biotechnology sector has grown by leaps and bounds since the 1990s. The industry has spawned giant companies in the medical space such as Gilead Sciences, Amgen, Biogen Idec and Celgene. At the other extreme are thousands of small, dynamic biotech companies, many of which are engaged in various aspects of the medical industry such as drug development, genomics, or proteomics, while others areinvolved in areas like bioremediation, biofuels and food products.

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Tuition and Fees | The American University in Cairo

Wednesday, August 8th, 2018

Tuitionfor Academic Year 2018- 2019

Tuition for Academic Year 2018 - 2019, Click Here.

Undergraduate Tuition

The following are the undergraduate tuition ratesper semester for the academic year 2018 - 2019 for new and current students:

Graduate Tuition

The following are the graduate tuition ratesper semester for the academic year 2018 - 2019for new and current students:

Non-Degree Tuition

The following are the non-degree tuition ratesper semester for the academic year 2018 - 2019:

For the academic year 2018 - 2019, tuitionis in Egyptian pounds for Egyptian students, and in U.S. dollarsfor international students.

Tuition and fees are collected each semester. No student with outstanding bill (including charges for breakage or library fines) will be admitted to any examination, given any certificate or report of academic standing, or be permitted to register for a subsequent semester.

Regulations

All payments must be made within theset deadlines.

Deferred Payment

Deferred payment installments:

When a degree-seeking student (undergraduate/graduate) is unable to pay the entire tuition amount at the time of registration, the student may apply for a deferred payment plan of two or three installments.

For New Students:

New students should apply at theStudent Service Center.

No deferred payment in the winter semester.

Fall 2018(newly admitted in Fall 2018)

Deadline for Payments

Spring 2019(newly admitted in Spring 2019)

To be paid on or before the deadline stated in your acceptance letter.

To be paid on or before the deadline stated in your acceptance letter.

For Current Students:

Current students should submit online deferred payment request through Banner Self Service.

Payment may be requested in two or three installments.

How to apply for Deferred Payment?

Students can submit online deferred payment request as follows:

Fall 2018Semester:

Installments

Deadline for Submission of the

Deferred Payment Application Form

Online

Two

Installments

2nd

Three

Installments

Spring 2019Semester:

Deadline for Submission of the

Deferred Payment Application Form

Online

Two

Installments

Three

Installments

Summer 2019 Semester:

Summer Tuition can only be paid on two installments.

Deadline for Submission of the

Deferred Payment Application Form

Online

Two

Installments

Important Notes:

Deferred Payment Calculation and Eligibility:

Please note that students who fail to submit the online application by the dates stated above, will have to pay the full tuition and fees.

For more information regarding deferred payment application tips and instructions, click here.

Requirements for Non-Egyptian Students Eligible to Pay Egyptian StudentTuition:

Non-Egyptian students who meet the requirements of admission for Egyptian students, and wish to pay the Egyptian studenttuition amountmust submit originals of the following documents.

Widowed mothers:

Divorced mothers:

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Tuition and Fees | The American University in Cairo

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Nano Engineering & Technology

Wednesday, August 8th, 2018

About Conference

Euroscicon invites globally all the leading academic scientists, researchers and research scholars from the Nano Engineering and technology to attend 22ndEdition of International Conference on Nano Engineering & Technology is scheduled from December 10-11,2018atRome, Italy.EuroSciCon is the UK based independent life science Events Company with predominantly business and academic client base.

The 2018 meeting is going to be dynamic and informative as it provides the premier interdisciplinary forum for researchers, practitioners, and educators to present and discuss the most recent innovations, trends, and concerns, practical challenges encountered and the solutions adopted in the field of Nanotechnology. The theme of the conference is about Future Challenges and Advanced Innovations in Nanotechnology!!!

This is a 2-day event. During the conference you can participate in General Sessions, Poster Presentations, and Workshops/Symposium, Meet-the-Professor Sessions, Oral Presentations and other interactive and informal exchanges.International symposiums, Panel Discussion and B2B meetings are organized based on the specific topics related to Nano Engineering and technology.

Topics discussed will be the forthcoming use of Nano technology in healthcare, electronics Nano materials, Nano Technology tools, Robotics, Computational Techniques and many more and other areas most recent techniques, developments, and the newest updates in Nano engineering & Nano technology.

We trust you will discover the Meeting beneficial, enlightening and agreeable. We want to personally thank the speakers, moderators, and other volunteers who are participating in the planning of this conference. Everyones energy is endless and everyones positive attitudes have amazed us throughout the year.

Nano Photonics is seen as a crucial technology which is expected to play a complementary role to micro/Nano electronics on chip and extend the capacity of telecommunication networks. Latest research is going on Nano photonics are Stability Formulation for Integrated Opto-mechanic Phase Shifters. Broadband achromatic metalens. From Two-Photon to Three-Photon Absorption. Detection of chemical and biological warfare agents. Fundamental and applied research into flexible electronics. Experimentation in electron beam lithography.

Ceramics and glass Materials are inorganic, non-metallic materials consisting of metallic and non-metallic elements. The high strength bonds in Ceramic & Glass Material gives rise to some of its special characteristics. They occupy a unique place in the field of engineered materials offering many desirable alternatives to the metals and polymers in common usage.

The Nano gadgets and Nanostructures have introduced a super exchange of the human race with its Nano way of life gadgets.. Nano scale materials are a broadly defined set of substances that have at least one critical dimension less than 100 nanometers and possess unique optical, magnetic, or electrical properties. Ultrafine particulate matter is a well-known example of nanoscale particles found in the environment

Biosensors converts the biological response into an electrical signals thereby the measurement is possible. The bio receptor may be a living organism or biological molecules, especially enzymes or antibodies. Measurement of target analyze without using any reagent is an added advantage of biosensor. New Sensor with a Breathalyzer. Optomechanical Nano sensor .hypoallergenic Electronic Sensor .optical Nano sensor Enhances Accuracy of Brain Mapping

Nano Robotics is a field under continuous development. It involves the construction of robots of the size of 10^-9m. In the last decade many Nano robots have made their way out of the drawing boards to enter into the human body and do things beyond. These robots play a key role in the field of biomedicine particularly used for the removal of kidney stone, treatment of cancer & elimination of defected part in the DNA structure etc. Special networks of stationery Nano robots will be positioned throughout the body which will keep the track of each active Nano robot passes & then report the results. Nanorobotics is also being developed for therapeutic manipulations.

Nano biotechnology is the application of nanotechnology in biotechnology. Applications in molecular diagnostics and pharmaceuticals, which include drug discovery, drug development, and drug delivery, are described. Nano biotechnology has refined the current molecular diagnostics by extending the limits of detection to single molecules. Nanoparticles play an important role in the delivery of biological therapies, which include cell therapy, gene therapy, vaccines, RNA interference, and antisense therapeutics. The most promising application of Nano biotechnology relevant to healthcare is for the development of personalized medicine. The refinement of molecular diagnostics, combination of diagnostics with therapeutics, and targeted drug delivery play important roles in this application. Finally, the safety issues of nanoparticles are discussed including measures to address these. The future prospects of Nano biotechnology are excellent the purpose of this sub track is to show, by selected examples, how biological approaches can contribute to Nano science

Due to the lack of novel drugs for the diseases, Nano pharmaceutical has appeared as an important new breakthrough for the treatment of neglected diseases like filiarasis, leishmaniasis, leprosy, malaria, onchocerciasis, schistosomiasis, trypanosomiasis, and tuberculosis. New developments in Nano carriers have made promising advances in the treatment of several kinds of diseases with less toxicity, high efficacy and improved bioavailability of drugs with extended release and fewer applications. This deals with the current status of medicines in the treatment of neglected diseases and highlights how it provides key tools for exploring new perspectives in the treatment of a wide range of diseases.

Green nanotechnology integrates the principles of green chemistry and green engineering to produce eco-friendly, safe, nanostructures that do not use toxic chemicals in the synthesis protocol. The parallel development of nanotechnology with green chemistry and potential synergism between the two fields can lead to sustainable methods with reduced environmental impacts, protection of resources and human health. With recent developments in nanostructures, concerns of uncertainty and risk regarding environment, health, and safety (EHS) cannot be ignored. Thus the concept of green nanotechnology comes to rescue. The main goal of green nanotechnology is to produce nanostructures without affecting the environment or human health. This can be a viable substitute to the conventional physical and chemical methods of synthesizing nanostructures.

The first and foremost requirement for the choice of the biomaterial is its adequacy by the human body. A biomaterial used for implant should possess some important properties in order to long term usage in the body without reputation. The thermal stabilities of the polymer chemistry were studied by means of thermogravimetric analysis. The activation energies of the degradation of the polymer chemistry were calculated using the Arrhenius equation. The rates of polymerization of polymers in the absence and in the presence of transition metal were studied.

Owing to their unique combination of physical and chemical properties such as high electrical conductivity, high surface area, high thermochemical stability, and adequate corrosion resistance, as well as particular mechanical properties, these materials have been the subject of several scientific studies. Unfortunately, the devoted effort to explore the fundamental physics, chemistry graphene, and carbon nanotubes is not enough to properly modulate in detail all the exceptional properties (including electrical, thermal, mechanical, optical, and long electron mean free paths).

Nanomedicine, the application of Nano biotechnology in medicine, is a broad term applied to all healthcare applications of Nano biotechnology. Clinical nanomedicine is used in practically all medical specialties and three areas cancer, neurological disorders, and cardiovascular diseases are described.

Smart materials are defined as materials with properties engineered to change in a controlled manner under the influence of external stimuli. Some of the external stimuli are temperature, force, moisture, electric charge, magnetic fields and ph. The self-assembly of peptides has enormous applications in the fields of medicine and electronics. Bio-inspired engineered systems have been designed based on the mechanistic perceptions obtained from natural systems for novel self-assembled structures. In the biological system, each cell type is programmed to display different levels of smartness.

Certain features of nanotechnology have been found that are likely to be important in determining its impact in the future. More importantly, responding to the challenge of nanotechnology will require confronting philosophical questions about the sort of society we wish to create and the role that technology might play in creating it.

Importance & Scope:

It is often seen as a new industrial revolution, and is incrementally attracting worldwide attention owing to its wide range of end-uses. Nanotechnology has huge development prospects owing to a wide range of potential products & applications, and there is an enormous scope for its commercial extension. The global nanotechnology market is expected to grow at a CAGR of around 17.5% during 2016-2022. Thus, there lies a huge chance for industry participants to tap the fast growing market. In 2015, the global nanotechnology market has shown impressive development supported by certain prominent factors, like acquiring significant amounts of public and private investments in R&D, partnerships & strategic alliances between the countries. At present, the bio-medical industry is one of the largest sectors in which Nano-enabled products have made crucial contributions, majorly in healthcare industry, with significant growth being done in other topics like electronics and energy as well. In this report, the analysts have considered the present nanotechnology marketplace on segment basis (by application, by component and by region), while covering the present market scenario as well as contributing forecasts for each of the indicated segments till 2021. The report covers an in-depth analysis of all the important segments, taking into account the key growth taking place at global level, like creations of new opportunities by different. The global market for the nanomaterial's in the year 2006 was around US $14,000, and the global investments are to be increased 50% more by the ending of 2019. The markets for nanotechnology products and nanotechnology uses are set to grow in the coming years

Why to attend ?

22ndInternational Conference on Nano engineering and Nanotechnology -2018 which is going to be the biggest conference dedicated to Nano engineering and Nanotechnology professionals providing a premier technical forum for reporting and learning about the latest new generation technologies developed during the course of time along with discussing their applications, this is your single best opportunity to reach the largest assemblage of participants from all over the globe. Nano engineering & Nanotechnology 2018 conference will be a great platform for demonstrations to distribute information and to meet the potential Students, Scientists Researchers Business Entrepreneurs make a splash with new product line, and receive name recognition at this 2-day event., the most recent techniques, developments, and the newest updates in Nano engineering & Nano technology will be discussed in the hall of this conferences.

Target Audience:

Nano engineering and Nanotechnology Students, Scientists Nano engineering and Nanotechnology Researchers Nano engineering and Nanotechnology Faculty Nano engineering and Nanotechnology Colleges Nano and Nanotechnology Associations and Societies Business Entrepreneurs Training Institutes Manufacturing Medical Devices Companies World-renowned speakers, the most recent techniques, tactics and the newest updates along with the Advances in the fields of Nano engineering & Nanotechnology.

Market Analysis

Nano science involves the study of phenomena and manipulation of matter on a Nano meter scale and development of a wide range of tools, objects, structures, devices, systems and techniques of nanotechnologies. This is a fast-growing area of research and development. It is widely predicted that the nanotechnologies will become a central focus for driving economic growth in the 21st century. These fields are attracting rapidly increasing investments from governments and from businesses across the globe. The aim of the current UK Strategy for nanotechnologies is to describe the actions necessary to ensure that the UK obtains maximum economic, environmental and societal benefit from nanotechnologies while keeping the risks properly managed (EPSRC).Nanotechnology has the ability to solve problems associated to human civilizations, pertaining to both basic needs and aspirations for a comfortable life. In addition, market trends like nanotechnology-based thin film solar cells with high efficiency; Nano materials with higher strength; robust growth in Nano fibers and Nano medicine market; etc., are booming growth in this industry. Considering the above factors, the global nanotechnology market is anticipated to grow at a CAGR of around 19% during 2013-2017.

.Nanotechnology has been the greatest incentive to technological and industrial development in the 21st century and has been recognized as the resource for the next industrial revolution. The evolving technology has already influenced a significant impact of industrial segments, and the economic activity generated from it has been high in magnitude and wide in scope. The nanotechnology-based products, which have had an enormous impact on almost each industrial sector, are now entering the consumer market in a big way On the application front, they have analyzed nanotechnology use in electronics, energy, cosmetics, medical and defense sector. In terms of component, the nanotechnology market can be segregated into Nano materials, Nano tools and Nano devices. The report covers their present and future shares in the market

Why in Rome, Italy

The nanotechnology market is driven by the ever increasing application base of and increasing emphasis on renewable and sustainable energy sector with the use of low cost materials. Moreover, initiatives of government for nano R&D and investments of technological giants propel the commercialization of next generation nanomaterials. The nanotechnology market is driven by increased demand from the end-use industries such as electronics, textile, pharmaceutical, biotechnology, aerospace, food and many others. Growing demand for efficient and cost-effective healthcare treatment and diagnostics propels the adoption of nanomaterials in drug delivery and medical devices sector. This is yet another reason which will drive the growth of nanotechnology in the near future.

Top Nanotechnology Universities, Organizations & Laboratories in Italy: -

Top Nanotechnology Companies and Industries in Italy

Recent Developments

In April 2012, Roberto Cingolani, director at the Istituto Italiano di Tecnologia (IIT) in Genoa, Italy, and his team developed a polymer from the monomers or molecules found in paper along with nanoparticles created in the lab. This polymer was mixed in a solution to create a polymeric matrix, which can be applied to paper either by injection, rolling, dipping or spray-coating. This nanotech paper is said to be waterproof, magnetic and antibacterial.

The 2012 Winter College on Nano-Optics and Plasmonics was organized by SPIE, the international society for optics and photonics, and seven other organizations in order to fulfill the demands of researchers and students in developing nations. It was conducted in February at the Abdus Salam International Centre for Theoretical Physics (ICTP) in Trieste.

In October 2012, the 'Nanoscience and nanotechnology 2012' conference took place in Rome. It showcased the recent developments in nanoscience and its manifold technological applications in various fields.

NanotechItaly 2012 was hosted at the Convention Center of the NH Hotel Laguna Palace Venice-Mestre from November 21st to 23rd. The conference was organized to showcase global efforts in nanotechnologies under the patronage of the President of the Italian Republic.

In May 2012, a team consisting of researchers from Italy and France were honored by the European Patent Office for their invention of nano-capsules, a drug delivery system with units 70 times smaller than red blood cells and protected by a biodegradable coating - which destroy cancer cells without harming healthy tissue.

Also in the same month, a team of Italian researchers developed an all optical method to measure the temperature of gold nanostars and nanorods during nanoparticle-induced hyperthermia, a method for treating cancer with heat.

There is no shortage of companies and organisations in Italy that are involved in nanotechnology. If their nanotech developments can match the attraction of Italy as a destination for nanotech conferences and events, they will be well placed to capitalise on the nanotechnology revolution. Two areas of synergy for Italy would be textiles and clothing and chemicals with existing industries well placed to be able to integrate nanotech solutions into new products.

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Nano Engineering & Technology

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Environmental Conferences | Climate Change conferences …

Wednesday, August 8th, 2018

Welcome Message

Dear Friends and Colleagues

It is my great honor and privilege to extend my warmest welcome you all tothe5th Edition of Euroscicon Conference onEnvironmental Science & Engineeringscheduled to be held from October 29-30, 2018 in Budapest, the beautiful capital city of Hungary. We are gathered here to discuss on the Environmental Science and Engineering, especiallySustainable Development of Environmental Science and Engineering towards Earth Science and Environmental Health.

This conference provides a platform to discuss environmental sciences and technologies in recent years and the conference highlight areEnvironmental Legislation,WasteManagement and Treatment,Green Chemistry,Environmental Geology and Earth Science,Atmospheric Sciences and Bio monitoring,Climate Changeand Public Health,Environmental Effects of Ozone Layer Depletion,Water Conservation and Hydro Power,Environmental Biotechnology, Fossil Fuels and Sources of Energy,Environmental Toxicology and Toxicity Assessment,Natural Resources and Biodiversity Conservation,Global Warming,Pollution Analysis and Environmental Sustainability,Ecology and Restoration Ecology,and so on.

The objective of the conference is to promote not only mutual exchange of scientific knowledge and technology, but also future cooperation of research among the scientists for maintaining better environmental states of the world related to the ecosystem for human and nature. I am sure that we will be listening to numerous exciting talks with new thoughts and observations through the useful presentations by multidisciplinary specialists in this conference. Papers related to the topics outlined above are invited and the others within scope of the conference are also welcomed.

This symposium is organized by EuroSciCon, founded in 2001 is a UK based independent life science events company with predominantly business and academic client base. The key strategic objective of EuroSciCon is to communicate science and medical research between academia, clinical practice and the pharmaceutical industry.

On behalf of the Organizing Committee I wish you a very successful and prosperous participation in this conference for contributing to the progress of various researches on better environment of the world.

March 2018

Dr. Hyo Choi,

Environmental Scientist & Professor, AODRI

Conference Chair of ESC 2018

EuroScicon is organising meeting onEnvironmental Science and Engineering 2018is scheduled fromOctober29-30atMercure Budapest Buda,Krisztina Krt 41-43., 1013,Budapest, Hungary. EuroScicon is the UK based independent life science events company with predominantly business and academic client base.

The 2018 meeting promises to be a dynamic and informative event and going to explore the issues, innovations and integrated approaches towardsenvironmentalsustainability, the speakers are a multidisciplinary gathering of globally perceived specialists that speak onSustainable Development of Environmental Science and Engineering Towards Earth Science and Environmental Health.

This is 2-days Meeting and you can participate in a number of educational formats including General Sessions, Poster Presentations, and Workshops/Symposium, Meet-the-Professor Sessions, Oral Presentations and other interactive and informal exchanges.

Topics will cover the latest advances in the Restoration Ecology, Earth Science and Climate Change, Renewable energy, Agricultural Production Systems & Agribusiness, Environmental Chemistry, Environmental Legislation and many more.

We trust you will discover the Meeting beneficial, enlightening and agreeable. We want to thank all EuroSciCon Members and participants whose commitments and cooperation have been basic to the accomplishment of the association!!

EuroSciCon are corporate members of the following organisations:

Opportunities for Conference Attendees:

For Universities, Associations & Societies:

For Students & Research Scholars:

For Business Delegates:

For Companies:

EuroSciCon organizesInternational Environmental Science and EngineeringMeetings annually across Europe, Austria, Ireland, Germany, France, Liechtenstein, Lithuania, Finland, Luxembourg, Hungary, Italy, Norway, Poland, Denmark, Macedonia, Greece, Portugal, Romania, Czech Republic, Switzerland, United Kingdom, Belgium, Scotland, Latvia, Ukraine, Sweden, Denmark, Spain, Netherlands Russia, Bulgaria, France, with solitary subject of quickening logical revelations.

About EnvironmentalScience and Engineering:

Environmental Science and Engineeringis the branch of engineering concerned with the application of scientific and engineering principles for protection of human populations from the effects of adverse environmental factors; protection of environments, both local and global, from potentially deleterious effects of natural and human activities; and improvement of environmental quality.

Environmental Engineeringcan also be described as a branch of applied science and technology that addresses the issues of energy preservation, protection of assets and control of waste from human and animal activities. Furthermore, it is concerned with finding plausible solutions in the field of public health, such aswaterborne diseases, implementing laws which promote adequate sanitation in urban, rural and recreational areas. It involveswaste water management,air pollutioncontrol, recycling,waste disposal, radiation protection, industrial hygiene, animal agriculture, environmental sustainability,public healthandenvironmental engineering law. It also includes studies on the environmental impact of proposed construction projects.

Environmental Engineers study the effect of technological advances on the environment. To do so, they conduct studies on hazardous-waste managementto evaluate the significance of such hazards, advise on treatment and containment, and develop regulations to prevent mishaps. Environmental engineers designmunicipal water supplyandindustrial wastewater treatmentsystems.They address local and worldwide environmental issues such as the effects ofacid rain,global warming,ozone depletion, water pollution and air pollution fromautomobile exhaustsandindustrial sources.

Conference Highlights:

Environmental Science

Environmental Engineering

Climate Change

Pollution

Pollution Analysis and Environmental Sustainability

Global Warming

Natural Resources

Energy Conservation

Recycling and Reuse

Green Chemistry

Ecology and Restoration Ecology

Fossil Fuel

Environmental Health Science

Renewable and Non-Renewable Sources Of Energry

Environmental Hazards

Human Impact On Environment

Environmental Legislation

Waste Management and Treatment

Environmental Geology and Earth Science

Atmospheric Sciences and Biomonitoring

Environmental Effects Of Ozone Layer Depletion

Water Conservation and Hydro-power

Environmental Toxicology and Toxicity Assessment

Environmental Biotechnology

Biodiversity Conservation

Environmental Marketing

Geology In Civil Engineering

About Subject:

Environmental Science and Engineeringis the application of science and engineering principles to enhance the environment, for example, air, water, as well as land resources, to provide healthy water, air, and land for human residence and for different creatures, and to remediate polluted sites.

Environmental engineeringis the branch of engineering that is concerned about shielding individuals from the impacts ofantagonistic natural impacts, for example, contamination, and also enhancing environmental quality. Environmental engineerswork to enhance recycling, waste disposal, public health, and water and air contamination control, as per the U.S. Bureau of Labor Statistics.

It utilizes the principles of biology and chemistry to develop solutions for ecological issues. The objective of environmental engineeringis to integrate scientific andengineering principlesto limit air contamination and waste discharge from industries, tidy up dirtied/polluted sites, set up proper mechanism for waste disposalresulting from human activity and study the impact of proposed construction sites on environment. Aside from this, environmental engineeringpromotes energy conservation and is also concerned with finding solutions in areas of public health such as implementing adequate sanitation facilities.

Subjects including environmental engineeringincorporate waste management, water supply,waste water treatment, air contamination,recycling and disposal of wastes, protection from radiation, public health, environmental engineering law, and the effects of man-made projects on the environment.

About Budapest, Hungary:

Budapest is the capital and most crowded city of Hungary, one of the biggest urban communities in the European Union and sometimes portrayed as the primate city of Hungary. It has a area of 525 square kilometers (203 square miles) and a population of around 1.8 million within the administrative limits in 2016. It is both a city and region, and structures the focal point of the Budapest Metropolitan Area, which has a region of 7,626 square kilometers. Budapest turned into a solitary city involving the two banks of the Danube River with the unification of Buda and buda on the west bank, with Pest on the east rely upon November 17, 1873. Budapest is an Alpha-worldwide city with qualities in the social insurance, inquire about, training, media, trade, plan, and tourism. Budapest is refered to as a standout amongst the most lovely urban communities in Europe positioned as the most liveable Central and Eastern European city on EIU's personal satisfaction file positioned as "the world's second best city" by Cond Nast Traveler and "Europe's seventh most pure place to live" by Forbes.

Budapest is home to more than 35 advanced education organizations, of which a substantial number of colleges. Under the Bologna Process, numerous offered capabilities are perceived in nations crosswise over Europe. Drug, dentistry, pharmaceuticals, veterinary projects, and building are among the most well known fields for nonnatives to attempt in Budapest. The focal zone of the city along the Danube River is delegated an UNESCO World Heritage Site and has numerous remarkable landmarks, including the Hungarian Parliament, Buda Castle, Fisherman's Bastion, Gresham Palace, Szchenyi Chain Bridge, Matthias Church and the Liberty Statue.

We are going to cover the following major scientific sessions in Environmental Engineering conference which is going to held in Budapest, Hungary from October 29-30, 2018.

Your suggestions related to the conference will be highly appreciated!!

Environmental Science:

Environmental science is likewise alluded to as an interdisciplinary field since it fuses data and thoughts from different orders. Inside the characteristic sciences, such fields as science, science, and geography are incorporated into ecological science. At the point when a great many people consider ecological science, they think about these common science viewpoints, yet what makes natural science such a perplexing and wide field is that it likewise incorporates fields from the sociologies and the humanities.The sociology handle that are consolidated into ecological science incorporate geology, financial matters, and political science. Logic and morals are the two fields inside the humanities that are likewise incorporated into ecological science. By joining parts of the normal sciences, sociologies, and the humanities, the field of natural science can cover more ideas and furthermore analyze issues and subjects from various perspectives.

Environmental Engineering:

Environmental Engineering alludes to the utilization of logical procedures to assist enhance the Earth's condition to give more beneficial land, water and air for human utilize and to discover approaches to downsize on contamination locales. It utilizes the standards of science and science to create answers for natural issues. The objective of natural building is to coordinate logical and designing standards to limit air contamination and waste release from enterprises, tidy up dirtied destinations, set up suitable system for squander transfer coming about because of human movement and concentrate the effect of proposed development locales on condition.Aside from this, natural designing advances vitality preservation and is likewise worried about discovering arrangements in zones of general wellbeing, for example, executing sufficient sanitation offices.

Waste Recycling And Reuse:

Shockingly, a lion's share of our waste discover route into lakes, streams, and seas. This damages arrive creatures, feathered creatures, marine creatures and in the end, people. At the point when storms happen, snow or rain streaming along their regular way made a beeline for waterways, streams, sewerage frameworks and tempest channels convey along rubbish littered on its course. The last goal is immense collections of life supporting waters. This marvel can prompt contamination of water sources and flare-up of sicknesses, for example, the runs and cholera. Reusing is the surefire method for alleviating contamination of life supporting water assets.

Environmental Legislation orEcological enactment is the gathering of laws and directions relating to air quality, water quality, the wild, jeopardized natural life and other ecological elements. The umbrella of ecological enactment covers numerous laws and controls, yet they all cooperate toward a shared objective, which is managing the collaboration amongst man and the common world to lessen dangers to nature and increment general wellbeing.

Human Impact On Environment:

Human effect on condition in a few ways, some normal impacts incorporate water quality, ecological contamination and ozone harming substance discharges, exhaustion of regular assets and commitment to environmental change. Some of these are the immediate aftereffect of human exercises, though others are auxiliary impacts that are a piece of a progression of activities and responses. However, innovation is making lives of people less demanding and agreeable. It represents an incredible danger to the earth. The risk is because of contamination, radiation perils, abuse of normal assets and so forth. Ozone harming substances and mist concentrates influence atmosphere by changing approaching sun oriented radiation and out-going infrared (warm) radiation that are a piece of Earth's vitality adjust. Changing the air plenitude or properties of these gases and particles can prompt a warming or cooling of the atmosphere framework.

Waste Management And Treatment:

Waste Management is the way toward treating strong squanders and offers assortment of answers for reusing things that don't have a place with junk. It is about how trash can be utilized as an important asset. Squander administration is something that every last family unit and entrepreneur on the planet needs. Squander administration discards the items and substances that you have use in a sheltered and proficient way. Some of the common ways of managing waste are Waste disposal, Landfills, Combustion, Recovery & Recyling, Plasma gasification, Composting, Waste minimization.

Green Chemistry:

Green chemistry, likewise calledsustainable chemistry, is a zone of science and compound building concentrated on the planning of items and procedures that limit the utilization and age of risky substances. Thoughecological sciencecentres around the impacts of contaminating chemicals on nature, green science centres around mechanical ways to deal with anticipating contamination and decreasing utilization of non-renewable assets. It is also known asGreen science.The general objectives of green scienceto be specific, more asset proficient and intrinsically more secure plan of particles, materials, items, and procedurescan be sought after in an extensive variety of settings.

Environmental Geology And Earth Science:

Environmental geology is the branch oftopographythat is worried about the associations amongst people and the geologic condition. Natural topography is basically a method for applying geologic learning to distinguish, remediate, and ideally keep, ecological issues from happening because of individuals.Environmental geologistsmust have a strong comprehension of right now happening geologic occasions, as well as authentic geologic occasions, for example, past quakes and surges. This information of the past is vital in light of the fact that it encourages them to show signs of improvement thought of what sorts of geologic occasions rehash themselves, with what recurrence they may happen, and what kinds of harm happened on account of those occasions. This is not the same as what a scientist (somebody who examines fossils) would do, on the grounds that natural geologists are worried about how the past is identifying with the present.

Atmospheric Science And Biomonitoring:

Atmospheric Chemistry is a branch of environmental science in which the science of the Earth's air and that of different planets is considered. It is a multidisciplinary approach of research and draws on natural science, material science, meteorology, PC displaying, oceanography, geography and volcanology and different orders. Research is progressively associated with different fields of concentrate, for example, climatology.

The sythesis and science of the Earth's air is of significance for a few reasons, yet essentially in view of the connections between the environment and living beings. The structure of the Earth's environment changes as consequence of characteristic procedures, for example, well of lava emanations, lightning and barrage by sun powered particles from crown. It has likewise been changed by human movement and some of these progressions are destructive to human wellbeing, products and biological systems. Cases of issues which have been tended to by climatic science incorporate corrosive rain, ozone consumption, photochemical exhaust cloud, ozone depleting substances and an Earth-wide temperature boost. Environmental scientific experts look to comprehend the reasons for these issues, and by acquiring a hypothetical comprehension of them, enable conceivable answers for be tried and the impacts of changes in government arrangement assessed.

Climate Change:

Climate change is influencing natural conditions for individuals and untamed life. As a aftereffect of changing natural conditions, climate change influences untamed life species both specifically and by implication. Current strategies impact the territory and dispersion of potential natural life living space. Because ofenvironmental change, approaches received to impact the administration of environments are relied upon likewise to influence the natural life living space and populaces that rely upon these biological systems (IPCC 2007, MEA 2005). Numerous scientists have investigated potential effects of environmental change on natural life populaces and territories, and additionally moves in vegetation groups coming about because of anticipated environmental change.

Link:
Environmental Conferences | Climate Change conferences ...

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Biotechnology – crbusa.com

Monday, July 30th, 2018

Driven to solve your unique challenges.

The biotechnology industry requires sophisticated, mixed-use facilities for product development, manufacturing, and distribution. Effective process-driven engineering coupled with an in-depth understanding of adaptive bioprocess design, and the requirements that impact it, are critical to meeting your unique design needs.

For more than three decades, CRB has specialized in delivering high-quality bioprocess facilities that are safe, reliable, and sustainable. Utilizing state-of-the-art methodologies and practices, we provide services across the entire project lifecycle, from conceptual design through preliminary and detailed design, construction, commissioning, and validation.

Our biotechnology teams are widely acknowledged as some of the top experts in their field.They actively participate in industry committees that help advance the standards andguidelines for biotech facilities and processes. Drawing fromtheunparalleled experience of our team of experts, many of whomhave worked atoperating companies themselves,CRB can provide a deep understanding of clinical, research, and regulatory requirements specific to your facility, as well as the processes that drive your business.

At CRB, we believe every project deserves acustomized approach.We work collaboratively with youtounderstand your needs, andwetailor our world-class expertise to find the right solutions for your technical challenges.Most importantly,we approach your project with the samemindset thatour founders instilled in thiscompany 30+ years ago -- we continually put your interests first. That's why, when partnering with CRB, you can be assured thatyour teamwill never be satisfied untilwe haveachieved success for your business!

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Biotechnology - crbusa.com

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Biotechnology and the Biotech Industry

Thursday, July 12th, 2018

Merriam-Webster defines biotechnology as the manipulation (as through genetic engineering) of living organisms or their components to produce useful usually commercial products (as pest resistant crops, new bacterial strains, or novel pharmaceuticals). Although this definition could broadly cover thousands of years of agriculture and animal breeding, the term biotechnology (often abbreviated as biotech) usually means the gene engineering technology that revolutionized the biological sciences starting with Cohen and Boyers demonstration of DNA cloning in their Stanford lab in 1973.

Since the first DNA cloning experiments over 40 years ago, genetic engineering techniques have developed to create engineered biological molecules, genetically designed microorganisms and cells, ways to find new genes and figure out how they work, and even transgenic animals and plants. In the midst of this bioengineering revolution, commercial applications exploded, and an industry developed around techniques like gene cloning, directed mutagenesis, DNA sequencing, RNA interference, biomolecule labeling and detection, and nucleic acid amplification.

The biotech industry broadly segments into the medical and agricultural markets. Although enterprising biotechnology is also being applied to other exciting areas like the industrial production of chemicals and bioremediation, the use in these areas is still specialized and limited. On the other hand, the medical and agricultural industries have each undergone a biotech revolution with newand often controversial research efforts, development programs, and business strategies to discover, alter, or produce novel biomolecules and organisms using bioengineering.

Biotechnology introduced a whole new approach to drug development that did not easily integrate into the chemically-focused approach most of the established pharmaceutical companies were using. This shift precipitated a rash of start-up companies starting with the founding of Cetus (now part of Novartis Diagnostics) and Genentech in the mid-1970s.

Since there was an established venture capital community for the high-tech industry in Silicon Valley, many of the early biotechnology companies also clustered in the San Francisco Bay Area. Over the years, several hundreds of start-up companies have been founded and hot-spots have also developed in the US around Seattle, San Diego, North Carolina's Research Triangle Park, Boston, and Philadelphia, as well as a number of international locations including areas around Berlin, Heidelberg, and Munich in Germany, Oxford and Cambridge in the UK, and the Medicon Valley in eastern Denmark and southern Sweden.

Medical biotech, with revenues exceeding $150 billion annually, receives the bulk of biotech investment and research dollars. Even the term biotech is often used synonymously with this segment. This part of biotech constellates around the drug discovery "pipeline" that starts with basic research to identify genes or proteins associated with particular diseases which could be used as drug targets and diagnostic markers. Once a new gene or protein target is found, thousands of chemicals are screened to find potential drugs that affect the target.

The chemicals that look like they might work as drugs (sometimes known as "hits") then need to be optimized, checked for toxic side effects, and, finally, tested in clinical trials.

Biotech has been instrumental in the initial drug discovery and screening stages. Most major pharmaceutical companies have active target-discovery research programs heavily reliant on biotechnology, and smaller new companies such as Exelixis, BioMarin Pharmaceuticals, and Cephalon do focused drug discovery and development often using unique proprietary techniques. In addition to direct drug development, there are companies like Abbott Diagnostics and Becton-Dickenson that are looking for ways to use new disease-related genes to create new clinical diagnostics.

A lot of these tests identify the most responsive patients for new drugs coming into the market. Also, supporting research for new drugs is a long list of research and lab supply companies that provide basic kits, reagents, and equipment. For example, companies such as Life Technologies, Thermo-Fisher, Promega and a host of others provide lab tools and equipment for bioscience research, and companies such as Molecular Devices and DiscoveRx provide specially engineered cells and detection systems for screening potential new drugs.

The same biotechnology used for drug development can also improve agricultural and food products. However, unlike with pharmaceuticals, genetic engineering did not generate a rash of new ag-biotech start-ups. The difference may be that, despite the technological leap forward, biotech did not fundamentally change the nature of the agricultural industry. Manipulating crops and livestock to optimize genetics to enhance utility and improve yields has been going on for thousands of years. In a way, bioengineering just provides a convenient new method.

Established agricultural companies, such as Dow and Monsanto, simply integrated biotech into their R&D programs.

Most of the focus on ag-biotech is on crop improvement, which, as a business, has been quite successful. Since the first genetically modified corn was introduced in 1994, transgenic crop staples such as wheat, soybean, and tomatoes have become the norm. Now, more than 90% of US-grown corn, soybeans, and cotton are bioengineered. Although lagging behind bioengineered plants, use of biotechnology for farm animal improvement is also pretty prevalent.

Remember Dolly, the first cloned sheep? That was in 1996. Now animal cloning is common, and it's clear transgenic farm animals are on the immediate horizon based on headlines highlighting recent developments on the Federation of Animal Societies' website. Although genetically modified organisms (GMOs) have generated a lot of controversy in recent years, ag-biotech has become pretty well established. According to the 2011 International Service for the Acquisition of Agri-biotech Applications' (ISAAA) 2011 report, 160 million hectares of GMO crops were planted in 2011 with sales of over $160 billion in engineered grain.

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Biotechnology and the Biotech Industry

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BBC – Ethics – Animal ethics: Biotechnology

Sunday, July 1st, 2018

BiotechnologyBiotechnologyJames Watson and the late Francis Crick discovered the structure of DNA in 1953; Watson has spoken in favour of genetic engineering

Biotechnology isn't something new - selective breeding to create more useful varieties of animals and plants is a form of biotechnology that human beings have used for thousands of years.

Biotechnology includes any use of science or technology to alter the characteristics of a particular breed or animal.

Biotechnology can be good or bad for animals - and it may also produce an answer to the ethical problems of experimenting on animals.

Transgenic animals raise a particularly difficult problem.

Newspaper articles about the ethical problems of genetically engineered animals are usually concerned about the danger these animals may pose to human beings (usually to human health), rather than any implications for the animals themselves.

Genetic engineering and selective breeding appear to violate animal rights, because they involve manipulating animals for human ends as if the animals were nothing more than human property, rather than treating the animals as being of value in themselves.

Recent action to allow animals to be patented reinforces the idea of animals as human property, rather than beings in their own right.

Biotechnology can be good for animals. Selective breeding and genetic engineering can benefit animals in many ways:

But biotechnology can also be bad for animals - the good effects for the breeder can offset by painful side-effects for the animals:

Profitability is one of the major drivers of both selective breeding and genetic engineering.

If animal welfare is not to be compromised, research must be restricted by a counter-balancing ethical principle that prevents altering animals in a way that was bad for the animal.

One writer, Bernard Rollin, suggests that a suitable rule to regulate genetic engineering would be this:

This principle can easily be adapted to cover selective breeding.

It's been suggested that genetic engineering may solve all the ethical problems of laboratory experiments on animals.The goal is to create a genetically engineered mammal that lacks sentience, but is otherwise identical to normal experimental animals.

Such an animal could not suffer whatever was done to it, so there should be no ethical difficulty in performing experiments on it.

Ethical problems:

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BBC - Ethics - Animal ethics: Biotechnology

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Comprehensive Biotechnology – 2nd Edition

Friday, June 29th, 2018

Editor-in-Chief

Volume Editors

Section Editors

General Preface

Nomenclature Guidelines

Permission Acknowledgments

1.01. Introduction

1.02. Amino Acid Metabolism

Glossary

1.02.1. Introduction

1.02.2. General Properties, Classification, and Structure of Amino Acids

1.02.3. Biosynthesis of Amino Acids

1.02.4. Catabolism of Amino Acids

1.02.5. Important Biomolecules Synthesized from Amino Acids

1.03. Enzyme Biocatalysis

Glossary

1.03.1. Introduction to Enzymes

1.03.2. Enzyme Kinetics

1.03.3. Enzyme Engineering

1.03.4. Enzyme Production

1.03.5. Immobilized Enzymes

1.03.6. Enzyme Applications

1.03.7. Conclusions

1.04. Immobilized Biocatalysts

1.04.1. Introduction: Definitions and Scope

1.04.2. Applications of Immobilized Enzymes

1.04.3. Methods of Enzyme Immobilization

1.04.4. Properties of Immobilized Enzymes

1.04.5. Evaluation of Enzyme Immobilization

1.04.6. Heterogeneous Biocatalysis

1.04.7. Future Prospects for Immobilized Biocatalysts

1.05. Lipids, Fatty Acids

Glossary

1.05.1. Introduction

1.05.2. Structure of Fatty Acids

1.05.3. Nomenclature

1.05.4. Form in the Cell

1.05.5. What Do Lipids Do?

1.05.6. Biosynthesis of Fatty Acids and Lipids

1.05.7. Biochemistry of Lipid Accumulation

1.06. DNA Cloning in Plasmid Vectors

Glossary

1.06.1. Introduction

1.06.2. Cloning Vectors: Replication Origins and Partition Regions

1.06.3. Cloning Vectors: Selection Markers

1.06.4. Preparing DNA Fragments for Ligation

1.06.5. Ligation Systems

1.06.6. Methods of Bacterial and Yeast Transformation

1.06.7. Exploitation of Bacteriophage Packaging for DNA Cloning in Plasmid Vectors

1.06.8. Screening of Plasmid Clones in Bacteria for the Desired Recombinant Plasmids

1.06.9. Vector-Implemented Systems for the Direct Selection of Recombinant Plasmids

1.06.10. Direct Selection of Recombinant Plasmids Involving Restriction Enzyme Digestion of the Ligation Mixture

1.06.11. Particular Features of Oligonucleotides Cloning

1.06.12. Particular Features of Cloning of PCR Amplicons

1.06.13. Introduction of Deletions into Plasmids

1.06.14. Instability of Recombinant Plasmids

1.06.15. DNA Cloning Using Site-Specific Recombination

1.06.16. DNA Cloning Using Homologous (General) Recombination

1.06.17. Employment of Transposons for In Vivo Cloning and Manipulation of Large Plasmids

1.06.18. Conclusion

1.07. Structure and Biosynthesis of Glycoprotein Carbohydrates

Glossary

Acknowledgments

1.07.1. Introduction

1.07.2. Monosaccharide Structure

1.07.3. Oligosaccharide Structure

1.07.4. Biosynthesis of Glycoproteins

1.07.5. Glycosylation of Therapeutic Glycoproteins

1.08. Nucleotide Metabolism

Glossary

1.08.1. Introduction

1.08.2. Synthesis of Phosphoribosyl Diphosphate (PRPP)

1.08.3. Purine Biosynthesis

1.08.4. Pyrimidine Biosynthesis

1.08.5. Nucleoside Triphosphate Formation

1.08.6. Deoxyribonucleotide Biosynthesis

1.08.7. Nucleotide Salvage

1.08.8. Purine and Pyrimidine Catabolism

1.08.9. Regulation of Gene Expression in Bacterial Nucleotide Synthesis

1.08.10. Exploitation of the Knowledge of Nucleotide Metabolism in Biotechnology

1.09. Organic Acids

Glossary

1.09.1. Introduction

1.09.2. Citric Acid

1.09.3. Gluconic Acid

1.09.4. Lactic Acid

1.09.5. Itaconic Acid

1.09.6. Other Acids

1.10. Peptides and Glycopeptides

Glossary

1.10.1. Introduction

1.10.2. Peptide Hormones

1.10.3. Neuropeptides

1.10.4. Antibacterial Peptides

1.10.5. Glycosylation Is a Common and Important Post-Translational Modification of Peptides

1.10.6. Common Glycosidic Linkages

1.10.7. Peptide Synthesis

1.10.8. Glycopeptide Synthesis

1.10.9. Peptides and Glycopeptides as Models of Proteins and Glycoproteins

1.10.10. Application of Synthetic Peptides and Glycopeptides for the Treatment of Disease

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Comprehensive Biotechnology - 2nd Edition

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