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Archive for the ‘Gene therapy’ Category

Vaccines Derived from Patients’ Tumor Cells Are Individualizing Cancer Treatment

Saturday, June 26th, 2010

The first discovery of a cancer gene marker--the BRAF oncogene for melanoma and colorectal malignancies--back in 2002 changed the way many researchers thought about cancer treatment. Rather than approach the disease based on what region of the body it stemmed from, scientists began to identify cancers in terms of their genetic signatures. Researchers now recognize more than 200 kinds of cancer--all genetically unique. [More]

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Cancer - Health - Conditions and Diseases - Colorectal cancer - Management of cancer

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Vaccines Derived from Patients’ Tumor Cells Are Individualizing Cancer Treatment

Saturday, June 26th, 2010

The first discovery of a cancer gene marker--the BRAF oncogene for melanoma and colorectal malignancies--back in 2002 changed the way many researchers thought about cancer treatment. Rather than approach the disease based on what region of the body it stemmed from, scientists began to identify cancers in terms of their genetic signatures. Researchers now recognize more than 200 kinds of cancer--all genetically unique. [More]

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Cancer - Health - Conditions and Diseases - Colorectal cancer - Management of cancer

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Cancer Therapy Goes Viral: Progress Is Made Tackling Tumors with Viruses

Thursday, June 24th, 2010

The adapted virus that immunized hundreds of millions of people against smallpox has now been enlisted in the war on cancer. Vaccinia poxvirus joins a herpesvirus and a host of other pathogens on a growing list of engineered viruses entering late-stage human testing against cancer. [More]

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Cancer - Smallpox - Virus - Vaccinia - Health

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Cancer Therapy Goes Viral: Progress Is Made Tackling Tumors with Viruses

Thursday, June 24th, 2010

The adapted virus that immunized hundreds of millions of people against smallpox has now been enlisted in the war on cancer. Vaccinia poxvirus joins a herpesvirus and a host of other pathogens on a growing list of engineered viruses entering late-stage human testing against cancer. [More]

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Cancer - Smallpox - Virus - Vaccinia - Health

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Large-Scale Autism Study Reveals Disorder’s Genetic Complexity

Saturday, June 12th, 2010

The vast array of behaviors that are seen in autism spectrum disorder seems to cover an even deeper range of genetic complexity just below the surface. And the largest genetic study of autistic children and their parents to date has located a host of new variations in autistic individuals. [More]

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Autism spectrum - Autism - Health - Mental health - Disorders

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Large-Scale Autism Study Reveals Disorder’s Genetic Complexity

Saturday, June 12th, 2010

The vast array of behaviors that are seen in autism spectrum disorder seems to cover an even deeper range of genetic complexity just below the surface. And the largest genetic study of autistic children and their parents to date has located a host of new variations in autistic individuals. [More]

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Autism spectrum - Autism - Health - Mental health - Disorders

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Alzheimer’s: Forestalling the Darkness with New Approaches (preview)

Friday, May 28th, 2010

In his magical-realist masterpiece One Hundred Years of Solitude , Colombian author Gabriel García Márquez takes the reader to the mythical jungle village of Macondo, where, in one oft-recounted scene, residents suffer from a disease that causes them to lose all memory. The malady erases “the name and notion of things and finally the identity of people.” The symptoms persist until a traveling gypsy turns up with a drink “of a gentle color” that returns them to health.

In a 21st-century parallel to the townspeople of Macondo, a few hundred residents from Medellín, Colombia, and nearby coffee-growing areas may get a chance to assist in the search for something akin to a real-life version of the gypsy’s concoction. Medellín and its environs are home to the world’s largest contingent of individuals with a hereditary form of Alzheimer’s disease. Members of 25 extended families, with 5,000 members, develop early-onset Alzheimer’s, usually before the age of 50, if they harbor an aberrant version of a particular gene.

[More]

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Alzheimer - Macondo - One Hundred Years of Solitude - Health - Conditions and Diseases

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Alzheimer’s: Forestalling the Darkness with New Approaches (preview)

Friday, May 28th, 2010

In his magical-realist masterpiece One Hundred Years of Solitude , Colombian author Gabriel García Márquez takes the reader to the mythical jungle village of Macondo, where, in one oft-recounted scene, residents suffer from a disease that causes them to lose all memory. The malady erases “the name and notion of things and finally the identity of people.” The symptoms persist until a traveling gypsy turns up with a drink “of a gentle color” that returns them to health.

In a 21st-century parallel to the townspeople of Macondo, a few hundred residents from Medellín, Colombia, and nearby coffee-growing areas may get a chance to assist in the search for something akin to a real-life version of the gypsy’s concoction. Medellín and its environs are home to the world’s largest contingent of individuals with a hereditary form of Alzheimer’s disease. Members of 25 extended families, with 5,000 members, develop early-onset Alzheimer’s, usually before the age of 50, if they harbor an aberrant version of a particular gene.

[More]

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Alzheimer - Macondo - One Hundred Years of Solitude - Health - Conditions and Diseases

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Schizophrenia shares genetic links with autism, genome study shows

Wednesday, May 12th, 2010

Schizophrenia involves some of the same genetic variations as autism and attention deficit disorders, a new whole-genome analysis study has confirmed. [More]

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Schizophrenia shares genetic links with autism, genome study shows

Wednesday, May 12th, 2010

Schizophrenia involves some of the same genetic variations as autism and attention deficit disorders, a new whole-genome analysis study has confirmed. [More]

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Biomarker Studies Could Realize Goal of More Effective and Personalized Cancer Medicine

Tuesday, April 27th, 2010

When President Richard Nixon launched the war on cancer in his January 1971 State of the Union, he called for "the same kind of concentrated effort that split the atom and took man to the moon." Yet nearly 40 years and $100 billion in federally funded cancer research later, it seems the lunar landing was a much less daunting task.

[More]

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Biomarker Studies Could Realize Goal of More Effective and Personalized Cancer Medicine

Tuesday, April 27th, 2010

When President Richard Nixon launched the war on cancer in his January 1971 State of the Union, he called for "the same kind of concentrated effort that split the atom and took man to the moon." Yet nearly 40 years and $100 billion in federally funded cancer research later, it seems the lunar landing was a much less daunting task.

[More]

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Rare flowers and common herbal supplements get unmasked with plant DNA barcoding

Tuesday, April 20th, 2010

NEW YORK--Will exotic orchids soon be subjected to the same genetic scrutiny as some luxury caviars? That is just one of the coding conundrums that scientists convened at the New York Botanical Garden in the Bronx to discuss on a cloudy mid-April afternoon. [More]

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Rare flowers and common herbal supplements get unmasked with plant DNA barcoding

Tuesday, April 20th, 2010

NEW YORK--Will exotic orchids soon be subjected to the same genetic scrutiny as some luxury caviars? That is just one of the coding conundrums that scientists convened at the New York Botanical Garden in the Bronx to discuss on a cloudy mid-April afternoon. [More]

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Faulty Circuits (preview)

Wednesday, April 7th, 2010

In most areas of medicine, doctors have historically tried to glean something about the underlying cause of a patient’s illness before figuring out a treatment that addresses the source of the problem. When it came to mental or behavioral disorders in the past, however, no physical cause was detectable so the problem was long assumed by doctors to be solely “mental,” and psychological therapies followed suit.

Today scientific approaches based on modern biology, neuroscience and genomics are replacing nearly a century of purely psychological theories, yielding new approaches to the treatment of mental illnesses.

[More]

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Faulty Circuits (preview)

Wednesday, April 7th, 2010

In most areas of medicine, doctors have historically tried to glean something about the underlying cause of a patient’s illness before figuring out a treatment that addresses the source of the problem. When it came to mental or behavioral disorders in the past, however, no physical cause was detectable so the problem was long assumed by doctors to be solely “mental,” and psychological therapies followed suit.

Today scientific approaches based on modern biology, neuroscience and genomics are replacing nearly a century of purely psychological theories, yielding new approaches to the treatment of mental illnesses.

[More]

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