StemCell Therapy

Laugwitz, K.L. et al. Postnatal Isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature 433, 647653 (2005).

Smart, N. et al. De novo cardiomyocytes from within the activated adult heart after injury. Nature 474, 640644 (2011).

Chen, Q. et al. Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells. Nat. Commun. 7, 12422 (2016).

Kumar, M.E. et al. Defining a mesenchymal progenitor niche at single-cell resolution. Science 346, 1258810 (2014).

Snippert, H.J. et al. Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell 143, 134144 (2010).

Klotz, L. et al. Cardiac lymphatics are heterogeneous in origin and respond to injury. Nature 522, 6267 (2015).

Sauer, B. & Henderson, N. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA 85, 51665170 (1988).

Nagy, A. Cre recombinase: the universal reagent for genome tailoring. Genesis 26, 99109 (2000).

Davis, J., Maillet, M., Miano, J.M. & Molkentin, J.D. Lost in transgenesis: a user's guide for genetically manipulating the mouse in cardiac research. Circ. Res. 111, 761777 (2012).

Tian, X., Pu, W.T. & Zhou, B. Cellular origin and developmental program of coronary angiogenesis. Circ. Res. 116, 515530 (2015).

Sauer, B. & McDermott, J. DNA recombination with a heterospecific Cre homolog identified from comparison of the pac-c1 regions of P1-related phages. Nucleic Acids Res. 32, 60866095 (2004).

Anastassiadis, K. et al. Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice. Dis. Model. Mech. 2, 508515 (2009).

Guo, C., Yang, W. & Lobe, C.G. A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action. Genesis 32, 818 (2002).

Beltrami, A.P. et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114, 763776 (2003).

Ellison, G.M. et al. Adult c-Kit+ cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair. Cell 154, 827842 (2013).

van Berlo, J.H. et al. c-Kit+ cells minimally contribute cardiomyocytes to the heart. Nature 509, 337341 (2014).

Hatzistergos, K.E. et al. Stimulatory effects of MSCs on c-Kit+ cardiac stem cells are mediated by SDF1CXCR4 and SCFc-Kit signaling pathways. Circ. Res. 119, 921930 (2016).

Molkentin, J.D. & Houser, S.R. Are resident c-Kit+ cardiac stem cells really all that are needed to mend a broken heart? Circ. Res. 113, 10371039 (2013).

Molkentin, J.D. Letter by Molkentin regarding article, The absence of evidence is not evidence of absence: the pitfalls of Cre knock-ins in the c-Kit locus. Circ. Res. 115, e21e23 (2014).

Liu, Q. et al. Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes. Cell Res. 26, 119130 (2016).

Yanger, K. et al. Robust cellular reprograming occurs spontaneously during liver regeneration. Genes Dev. 27, 719724 (2013).

Pu, W. et al. Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration. Nat. Commun. 7, 13369 (2016).

Zorn, A.M. & Wells, J.M. Vertebrate endoderm development and organ formation. Annu. Rev. Cell Dev. Biol. 25, 221251 (2009).

Tarlow, B.D., Finegold, M.J. & Grompe, M. Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury. Hepatology 60, 278289 (2014).

Furuyama, K. et al. Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat. Genet. 43, 3441 (2011).

Font-Burgada, J. et al. Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer. Cell 162, 766779 (2015).

Sultana, N. et al. Resident c-Kit+ cells in the heart are not cardiac stem cells. Nat. Commun. 6, 8701 (2015).

Hatzistergos, K.E. et al. c-Kit+ cardiac progenitors of neural crest origin. Proc. Natl. Acad. Sci. USA 112, 1305113056 (2015).

Carpentier, R. et al. Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes and adult liver progenitor cells. Gastroenterology 141, 14321438 (2011).

Yanger, K. et al. Adult hepatocytes are generated by self-duplication rather than stem cell differentiation. Cell Stem Cell 15, 340349 (2014).

Awatramani, R., Soriano, P., Rodriguez, C., Mai, J.J. & Dymecki, S.M. Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nat. Genet. 35, 7075 (2003).

Engleka, K.A. et al. Islet1 derivatives in the heart are of both neural crest and second heart field origin. Circ. Res. 110, 922926 (2012).

Jensen, P. et al. Redefining the serotonergic system by genetic lineage. Nat. Neurosci. 11, 417419 (2008).

Plummer, N.W. et al. Expanding the power of recombinase-based labeling to uncover cellular diversity. Development 142, 43854393 (2015).

Plummer, N.W., de Marchena, J. & Jensen, P. A knock-in allele of En1 expressing Dre recombinase. Genesis 54, 447454 (2016).

Wang, X. et al. Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature 422, 897901 (2003).

Alvarez-Dolado, M. et al. Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425, 968973 (2003).

Vassilopoulos, G., Wang, P.R. & Russell, D.W. Transplanted bone marrow regenerates liver by cell fusion. Nature 422, 901904 (2003).

Ruzankina, Y. et al. Deletion of the developmentally essential gene Atr in adult mice leads to age-related phenotypes and stem cell loss. Cell Stem Cell 1, 113126 (2007).

Sohal, D.S. et al. Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein. Circ. Res. 89, 2025 (2001).

Liu, Q. et al. c-Kit+ cells adopt vascular endothelial but not epithelial cell fates during lung maintenance and repair. Nat. Med. 21, 866868 (2015).

Madisen, L. et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat. Neurosci. 13, 133140 (2010).

Zhang, H. et al. Endocardium contributes to cardiac fat. Circ. Res. 118, 254265 (2016).

Zhang, H. et al. Endocardium minimally contributes to coronary endothelium in the embryonic ventricular free walls. Circ. Res. 118, 18801893 (2016).

Zhang, H. et al. Genetic lineage tracing identifies endocardial origin of liver vasculature. Nat. Genet. 48, 537543 (2016).

Liu, Q. et al. Genetic targeting of sprouting angiogenesis using AplnCreER. Nat. Commun. 6, 6020 (2015).

Tian, X. et al. Sub-epicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res. 23, 10751090 (2013).

He, L. et al. Genetic lineage tracing discloses arteriogenesis as the main mechanism for collateral growth in the mouse heart. Cardiovasc. Res. 109, 419430 (2016).

Zhou, B. et al. Adult mouse epicardium modulates myocardial injury by secreting paracrine factors. J. Clin. Invest. 121, 18941904 (2011).

Tag, C.G. et al. Bile duct ligation in mice: induction of inflammatory liver injury and fibrosis by obstructive cholestasis. JoVE 96, e52438 (2015).

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Enhancing the precision of genetic lineage tracing using ...

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