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Open Forum: Hate can cause blindness and corruption – The Winchester Star

January 25th, 2020 1:46 am

Almost half of my family and many of my good friends cant stand Donald Trump. Others are so consumed with a deep-seeded hate that their ability to see reality is obscured.

For the past three years, Trump has been subjected to a non-stop, 24 hour/day smear campaign. He has been called: traitor, racist, fascist, homophobic, misogynistic, scumbag, sleazy, warmonger, worst president ever, and often accused of being mentally unstable. Some have called him a Nazi, and compared him to Hitler. A significant number of people dont like his tone, others dont like his character. The negative publicity includes the deliberate withholding and outright distortion of news that would favor Trump ... so its no wonder that many hate him.

The recent Impeachment vote by the House of Representatives was nothing more than a well-orchestrated attempt to smear President Trump. Democrats knew from the beginning that there was no evidence of a High Crime or Misdemeanor. They invented non-criminal charges in an unfair rush to impeach.

The Trump haters ignore this disgraceful congressional abuse of power because their hate overcomes what is an obvious attempt to smear.

Hate has succeeded in blinding many people from what could be the greatest political scandal in the history of our country. The Mueller investigation, coupled with the Inspector Generals investigation, clearly show that Donald Trump has been a victim of a deep-state, secret attempt to overthrow his presidency. If it can happen to Trump, it can happen to anyone.

The haters are blind to Trumps positive impact on economic prosperity that has resulted in more jobs available than workers to fill them; the haters are blind to the threat of Socialism that has infected the Democratic Party; and, worst of all, the haters are blind to the many domestic threats that are right before their eyes: Threats to the Right of Due Process, the Right of Free Speech, and the Right to Bear Arms; Threats to pack the Supreme Court and Abolish the Electoral College; Support for Open Borders and Sanctuary Cities; Promises of full benefits and rights for Illegal Immigrants; and Monstrous tax and spend proposals that would destroy the American Dream.

The haters are so focused on defeating Trump, that they are blind to the freedom-destroying strategies that are the bait-and-switch deceptions of Socialism. Corrupt politicians offer voters the delicious temptation of wonderful benefits that others will pay for. These politicians love the effectiveness of hate. Especially when the haters ignore the fact that Trump is term-limited. They need to wake up and realize that Socialism has no term limits!

This 2020 Presidential election will determine the future of our free Republic. It is truly a choice between Freedom, and Government-dictated Socialism.

James T. Holland is a resident of Frederick County.

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His Mother Worked to Find Him Love Despite War, Blindness and Loss – The New York Times

January 25th, 2020 1:46 am

On the wedding day, a small convoy of cars set off from Mr. Zindanis home to the brides, snaking through Kandahars streets as an excited 14-year-old drummer provided a soundtrack from the back of a three-wheeler.

Mr. Zindani seemed happy and excited, too. He said that what remained of his previous love, and the heartbreak of it, was now largely limited to poetic inspiration. He recited one of his latest verses:

I came to this alley to ask about my love

I wander in ruins; I hoped she hears my sigh.

He said that he was stuck with images of his life before he went blind; since the bombing he is unable to visualize new acquaintances.

Love with open eyes when you have fallen in love with someone you have seen is different with that of closed eyes, Mr. Zindani said. When you cant see the person, the thirst is not fulfilled the same.

At Simas house, the men were led to the veranda of an open-air mosque and the women into her home. The men sipped orange soda as the sun set while the womens voices, singing to a simple hand drum called a daf, echoed through the neighborhood. The ceremony ended in about an hour, with a prayer by a local imam who wished the newlyweds eternal love the kind between the Prophet Muhammad and his wife Khadija.

As the bride made her way out of her parents home and into the car adorned in flowers, Mr. Zindanis friends danced in celebration in front of it. The young drummer played a simple rhythmic beat in the dim light of the moon.

When the convoy returned to Mr. Zindanis house with the bride, the women, still singing and playing their daf, took her inside to her throne where the party would continue into the night. Mr. Zindani stayed outside, in the dark alley, as his friends continued to dance.

One friend spun and spun and spun, until the young drummers hands tired and he signaled its end.

I wish I could see it, Mr. Zindani said. But my heart is happy.

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Start young to prevent age-related vision loss – The Daily Freeman

January 25th, 2020 1:46 am

KINGSTON, N.Y. If you ever thought cool shades were a mere fashion statement, think again. Wearing good sunglasses may help to prevent blindness as you age, an eye doctor told a group of seniors at a recent event in Kingston.

Aging is hard enough, but age-related blindness is enough to challenge anybody. On Wednesday, Jan. 15, the Health Alliance presentation to the Seniors Health and Wellness Breakfast Club at the Marys Avenue hospital campus focused on glaucoma and macular degeneration, two common eye diseases that afflict people as they age.

Dr. Sankara Mahesh, an ophthalmologist based at Westchester Medical Center in Valhalla, N.Y., spoke to the group of seniors, using slides and pictures to explain how these diseases develop and how to (possibly) prevent them.

Glaucoma, said Mahesh, is a leading cause of vision loss in the United States. There are 3 million people in the U.S. who suffer from it, he added.

Mahesh explained that glaucoma happens when the pressure inside the eye is inappropriate. That means its either too high, or (less frequently) too low. Eye pressure usually does not relate to a persons blood pressure, although a low diastolic blood pressure may indicate low eye pressure.

Eye pressure is so important because the eye is nourished by fluid that is constantly introduced to and drained from the eye. When for some reason the drain is blocked, eye pressure goes up. If theres not enough fluid, eye pressure goes down. Without the appropriate amount of nourishing fluid, silent, irreversible damage to the optic nerve begins.

Fifty percent of people who have [glaucoma] dont know it, said Mahesh. There are no early symptoms. It slowly affects peripheral vision. Damage is slow and subtle, and takes place over a number of years.

The bad news: The damage is irreversible. And glaucoma, noted Mahesh, does not go away. The good news: Early detection can prevent vision loss.

At age 40, people should get a comprehensive eye exam, said Mahesh, and then continue to have eye exams yearly. Anyone can get glaucoma, but risk factors include age, family history, eye trauma, and African, Asian or Hispanic heritage.

Using eye drops to lower eye pressure is the usual treatment, but there are surgical interventions, as well. Mahesh noted that there are a number of recent advances in minimally invasive surgery, and some new devices for treating glaucoma are coming soon.

Prevention includes regular exercise and a diet rich in fruits and vegetables. Smoking and stress increase risk (meditation is recommended), as does diabetes and being overweight. Being underweight is also a risk factor.

Sunglasses are a preventive measure for macular degeneration, but the glasses must block UVA and UUB rays. Darker color doesnt mean it protects better, said Mahesh. And polarized sunglasses may help reduce glare, but they do nothing to protect from macular degeneration.

Macular degeneration is caused by damage to the macula, the part of the retina that is at the back of the inner eyeball.

Again, heredity is a risk factor for macular degeneration, a blindness that begins in the center of the visual field, but heredity is not a foregone conclusion. Having a sibling or parent with the condition doesnt mean you will develop it.

Smokers have two times the risk as non-smokers, and Caucasians are more likely to develop macular degeneration than other groups.

The cause is not exactly known, said Mahesh. It may be wear and tear or sunlight exposure. Drusen, the small, yellow lipids (fatty proteins) that grow under the retina, are suspected culprits.

There is no good way to treat the disease, other than by taking a combination of vitamins that may slow its progress. Ten percent of people with macular degeneration have the wet kind, which means that there is bleeding and swelling inside the eye. This type can be helped with eye injections.

Again, prevention and regular eye exams are key to maintaining good eye health, including a healthy diet, exercise and not smoking.

The Seniors Health and Wellness Breakfast Club, open to individuals age 65 and older, meets monthly at the Nuvance Health Alliance hospital on Marys Avenue from 8 a.m. to 10 a.m. to eat, socialize and learn more about a variety of health issues.

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What Is Snow Blindness & How Can You Prevent It? – University of Utah Health Care

January 25th, 2020 1:46 am

Jan 20, 2020 7:00 AM

Author: Moran Eye Center

Theres a reason you squint in bright sunlight. Your eyes are begging for protection against the glare of ultraviolet (UV) rays. But in situations where the suns rays intensify as they reflect off of snow, water, or sand, that begging might turn into screaming if you forget your UV-blocking sunglasses or goggles, because yesyour eyes can get sunburned.

Known generally as snow blindness and technically as photokeratitis (photo for light and keratitis inflammation of the cornea), sunburned eyes can sneak up on you. As with sunburned skin, by the time you notice the symptoms of snow blindness, youve already been out in the sun too long.

Symptoms include:

Your eyes and eyelids may swell, and you could get a headache.

You may not even experience the symptoms until several hours after the burn occurs, according to John A. Moran Eye Center Ophthalmologist Jean Tabin, MD. Luckily, they are temporary and should subside in a day or two.

If you suffer snow blindness, the best thing to do is give your eyes a rest. Stay indoors and wear sunglasses to reduce the amount of light exposure. If you wear contacts, take them out. Use preservative-free artificial tears to keep your eyes moistthink of it like using aloe vera for sunburn on your skin. Whatever you do, dont rub your eyes. This will only worsen the irritation.

If symptoms are severe, it may be best to see an ophthalmologist. You dont want to risk long-term damage.

The best way to protect against snow blindness is to protect your eyes with sunglasses. It doesnt necessarily matter how dark they are, as long as they block 99 percent of the suns UV rays. Wear them, even on overcast days, as UV rays can penetrate clouds.

Bigger ones are better in the winter, notes Tabin. Wearing goggles or sunglasses that wrap around will give you the most protection.

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Dog with ‘wonky’ face from early injury gets adopted: ‘He just needed patience’ – FOX 2 Detroit

January 25th, 2020 1:46 am

Brodie the German Shepherd Border Collie was left with a wonky face and partial blindness after being attacked after birth. ( SWNS )

One sweet rescuedogis enjoying his fairy-tail ending in afur-ever homeafter receiving hundreds of adoption requests.

The spirited German Shepherd Border Collie was left with a wonky face and partial blindness after being attacked after birthand was returned to the shelter when his initial owners couldnt handle his hyper personality.

Brodie the pup is officially living his best life after being adopted by Amanda Richter and Brad Ames. The couple said it was love at first sight when they saw photos of the wonky-faced dog online, and rescued him from Old MacDonald Kennels in Alberta, Canada in September last year.

Brave Brodie has grown up with severe cranial and facial injuries after being attacked by his mother at just 13 days old, news agency South West News Service (SWNS) reports. After the incident, part of the dogs jaw fused together as he grew, leaving one side of his face slanted with partial blindness in one eye.

Brad Ames and Amanda Richter with Brodie. (SWNS)

The adorable border collie spent just five months with his initial adoptees, and his first owners returned him because he had too hyper of a disposition.

Richter, meanwhile, said she was instantly drawn to Brodie and his resilience through his difficult start in life.

Brave Brodie has grown up with severe cranial and facial injuries after being attacked by his mother at just 13 days old. (SWNS)

I looked at his photos every day and even cried a few times. We felt drawn to him for some reason, the 30-year-old woman said. We met him, took him for a walk and hung out with him for a few hours and ended up bringing him home the same day because the rescue really felt we were a great fit.

Hes definitely hyper but he is so intelligent, she explained. His brain is perfectly fine and he learns tricks within 10 minutes usually which tells me he is a smart boy.

Brodie with the couple's other dog Rosie. (SWNS)

He just needed patience and someone to be consistent. He gets better every week.

He just needed patience and someone to be consistent. He gets better every week," his proud owner said. (SWNS)

As Brodie grows up, Richter and Ames, 23, have big dreams for their precious pooch. The proud ownershopeto train him as a therapy dog for people with special needswhile raising awareness for other disabled dogs.

Today, Brodie's owners hope to train him as a therapy dog for people with special needs, while raising awareness for other disabled dogs. (SWNS)

Though other medical complications may arise as he grows, Richter said shes simply thankful her dog is healthy and happy right now.

Its actually funny because when we go to the dog park everyone notices how he is the happiest pup there and just wants to play and run, she said. Dogs are resilient and he has no idea he looks different so he enjoys his life just the same as any other pup.

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Sucheta Kamath, Founder and CEO of ExQ, announces she will speak at Leadership Atlanta’s What’s the Big Idea, Tuesday, February 4, 2020 in Atlanta, GA…

January 25th, 2020 1:46 am

Sucheta Kamath, Founder and CEO of ExQ, a new cloud based personalized training curriculum designed to empower educators to teach Executive Function skills, is thrilled to announce she has been selected as one of Leadership Atlanta's top leaders to speak at their upcoming event: Atlanta What's the Big Idea, on Tuesday, February 4, 2020.

ATLANTA, Jan. 24, 2020 /PRNewswire-PRWeb/ -- Sucheta Kamath, Founder and CEO of ExQ, a new cloud based personalized training curriculum designed to empower educators to teach Executive Function skills, is thrilled to announce she has been selected as one of Leadership Atlanta's top leaders to speak at their upcoming event: Atlanta What's the Big Idea, on Tuesday, February 4, 2020.

Alumnus of Leadership Atlanta Class 2015, Sucheta Kamath is also the founder of ExQ, an educator, a TEDx speaker, a podcast host, and an award-winning speech-language pathologist. As an EdTech entrepreneur, she's on a mission to empower all learners to cultivate self-awareness and hone their Executive Function skills to learn how to learn.

"I'm thrilled to have been selected as one of Atlanta's top leaders sharing ideas to change the future of our city," shares Sucheta. "I look forward to presenting my Big Idea with Atlanta: No more self-blindness! Tapping into the patterns of thinking, emotions and actions to harness your strengths and reshape your weaknesses."

Sucheta Kamath, Founder, ExQ, believes learning Executive Function know how is basic to education, just as learning to read and write is basic to education. Each is a skill that must be taught, learned, practiced and is foundational for advancing. In her Leadership Atlanta Big Ideas presentation she will share, "Innovation in education has more to do with building Executive Function into everyday curriculum and coaching every child intentionally, so that when self-blindness becomes self-awareness the educational experience opens up to infinite know how and lifelong learning."

Celebrating 48 years of developing leaders, Leadership Atlanta is the oldest sustained community leadership program in the nation. Together with an expansive network of distinguished alumni, Leadership Atlanta continues a proud tradition of connecting and inspiring leaders to strengthen Metro Atlanta's communities.

Leadership Atlanta is hosting this half-day event of transformation and inspiration on Tuesday, February 4th, 2020 at the Alliance Theater in Atlanta, Georgia. During the event, Leadership Atlanta Alumni will harness the creativity and mind power of eight Atlanta leaders and their ideas to fundamentally change our city and our future. Participants will have the opportunity to:

All active Leadership Atlanta and LEAD Atlanta alumni, their guests and VIP community partners are invited to join for this exclusive kickoff event. For more information visit: https://www.onebigideaatlanta.com.

About ExQ: Rooted in more than 20 years of cognitive neuroscience and Executive Function training expertise, ExQ is a cloud-based patented system designed to enhance the brain's Executive Function through personalized game-based training that focuses on teaching students to learn how to learn. Learn more about a leading woman in technology, ExQ Founder and CEO, Sucheta Kamath, and Executive Function training with ExQ for School, for College, for Work, and for Life at https://exqinfiniteknowhow.com.

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Sucheta Kamath, Founder and CEO of ExQ, announces she will speak at Leadership Atlanta's What's the Big Idea, Tuesday, February 4, 2020 in Atlanta, GA...

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God, Sex and the Meaning of Life: Come explore the beauty and power of the Theology of the Body – denvercatholic.org

January 25th, 2020 1:46 am

By JD Flynn/Catholic News Agency

President Donald Trump addressed the annual March for Life Friday, telling pro-life demonstrators that he is an advocate for the right to life of unborn children, and calling for a federal prohibition on late-term abortion.

The president spoke about his commitment to the unborn, his administrations record on abortion policy, while criticizing Democrats at the state and federal level for their positions on human life.

He is the first president to attend in person the March for Life, which began in 1974 and has become one of the largest annual political events in the country.

All of us here understand an eternal truth: Every child is a precious and sacred gift from God, Trump told the crowd, which spanned across a large section of the National Mall and which the president described as a tremendous turnout.

Were here for a very simple reason, to defend the right of every child born and unborn to fulfill their God-given potential, the president said.

As President of the United States, I am truly proud to stand with you, Trump said.

Together we must protect, cherish, and defend the dignity and the sanctity of every human life.

You embrace mothers with care and compassion, you are powered by prayer and motivated by pure, unselfish love, the president told the crowd.

Trump especially praised the college and high school students in attendance at the March for Life.

Young people are the heart of the March for Life, and its your generation that is making America the pro-family, pro-life nation. The life movement is led by strong women, amazing faith leaders, and brave students, who carry on the legacy of pioneers before us, who fought to raise the conscience of our nation and uphold the rights of our citizens, Trump said.

The presidents attendance at the March for Life was announced earlier this week. Last year, Vice President Mike Pence attended the march, and in 2018, Trump welcomed pro-life leaders to the White House Rose Garden on the same day as the March.

The presidents unexpected attendance at the March led to heightened security. Initial security announcements said that no strollers would be permitted at the event, leading to criticism from March attendees who had brought children to the event. Security organizers eventually relented on the stroller policy, saying the initial prohibition was the result of a miscommunication

Trump took the stage shortly after noon to chants of four more years from some, but not all, in the crowd. Some attendees held signs distributed by the presidents campaign team, some of which read Most Pro-Life President Ever.

Before he spoke, Trump greeted leaders on the stage while Lea Greenwoods God Bless the U.S.A played. Before he had taken the stage, songs from the Rolling Stones and Tina Turner played, as well as The Animals 1964 House of the Rising Sun.

The presidents attendance was welcomed enthusiastically by March organizers. As she introduced Trump, March for Life president Jeanne Mancini thanked the president for coming.

Describing the March for Life as a pro-life and pro-woman event, and the largest human rights demonstration in the entire world, Mancini told Trump that your presence here today makes a very powerful statement.

You are leader of the free world and you stand for life. Thank you for being here. Thank you for everything youve done for life. And thank you for everything you will be doing for life in the years ahead, Mancini said, seeming to make reference to the presidents upcoming election.

The welcome marked a stark contrast to a March 2016 statement from Mancini, who responded to remarks from Trump calling for the imprisonment of women who undergo abortions as completely out of touch with the pro-life movement and even more with women who have chosen such a sad thing as abortion.

Being pro-life means wanting what is best for the mother and the baby. Women who choose abortion often do so in desperation and then deeply regret such a decision. No pro-lifer would ever want to punish a woman who has chosen abortion, Mancini added in 2016.

But Trump has made efforts since his 2016 election to respond to the policy proposals of pro-lfe leaders, administration officials say.

On Friday, he touted some of those efforts, mentioning his expansion of the Mexico City policy that bars federal funding from supporting abortions in foreign countries, along with his 187 appointments to the federal bench, among them two justices of the Supreme Court. The president also mentioned new regulations on Title X policies that block abortion providers from some federal funds.

Trump said that his administration is concerned about protecting religious liberty, and is taking care of doctors, teachers, nurses, and groups like the Little Sisters of the Poor.

Unborn children have never had a stronger defender in the WH, the president said, to applause from the crowd.

Trump has faced fierce criticism from the U.S. bishops conference and other faith leaders for his immigration and social welfare policies, and did not make mention of those issues during his speech. Nor did he mention his recent drone strike against Iranian general Qasem Soleimani, which has also drawn criticism from faith leaders who have raised concerns about the possibility that the U.S. could enter another war in the Middle East.

The president also did not mention directly his reelection, but he did tell the crowd that Democrats have embraced the most radical and extreme positions taken and seen in this country for years and decades, and you can even say, for centuries. Nearly every top Democrat in Congress now supports taxpayer-funded abortions all the way up until the moment of birth.

Trump mentioned the 2019 passage of New York states Reproductive Health Act, which ushered in a wave of legislation in several states aimed at expanding legal protection for abortion. He also mentioned Virginias Governor Ralph Northam, who in 2019 made public comments that seemed to support allowing a child who survived a botched abortion to die without medical treatment.

The president did not mention Louisiana state Rep. Katrina Jackson, a pro-life Democrat scheduled to speak at the March for Life shortly after Trump. Jackson sponsored a Louisiana law requiring doctors performing abortions to have admitting privileges at a hospital within a 30-mile radius. That law, now under judicial review at the Supreme Court, is expected to pose a challenge to the binding precedent of Roe v. Wade.

Trump is currently subject to impeachment proceedings in the U.S. Senate, which he did not mention directly in his speech. He did, however, aim to connect his political challenges to his pro-life advocacy.

Sadly the far left is actively working to erase our God-given rights, shut down faith-based charities, ban religious believers from the public square, and silence Americans who believe in the sanctity of life, Trump told the crowd.

They are coming after me, because I am fighting for you, and we are fighting for those who have no voice, and we will win, because we know how to win.

We all know how to win. Youve been winning for a long time. Youve been winning for a long time, Trump told the crowd.

As he closed his remarks, the president told the crowd his attendance was a very special moment.

It is so great to represent you. I love you allGod bless America.

As Trump left the stage, the Rolling Stones 1969 classic You Cant Always Get What You Want played over the speakers.

Christine Rousselle contributed to this report.

Featured image by Peter Zelasko/CNA

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It was important to me to make an everyday kid a hero – AOP

January 25th, 2020 1:46 am

My vision

Author Ben Shaberman talks to OT about how families affected by blindness helped to inspire his new novel, Retina Boy

24 Jan 2020 by Ben Shaberman

I have been with the Foundation Fighting Blindness in the US for about 15 years. My role is to report on research for retinal diseases, such as retinitis pigmentosa, Stargardt disease and age-related macular degeneration. I write articles, give talks and work with families and people who are affected by these diseases. While my role is to give hope to those who are affected, I have always been inspired by the families, especially the young kids, who are born with these conditions.

These children who are born with virtually no vision are often happy, successful, productive kids. Even though my organisation and myself are supportive of identifying treatments and cures, I wanted to do something that honoured and made a hero of these kids who are born blind so I decided to write a book.

The plot starts out with a newborn baby who has very little retinal tissue. The researchers are mystified because they have never seen a condition like it. Early on in the story a classmate calls him Retina Boy and the name sticks.

I would say Retina Boy is somewhat of a superhero, but not in the classic sense of having amazing super powers. It was important to me to make an everyday kid a hero. His friend, Marcy, cant walk so she uses a wheelchair. They make a perfect pair because she can be his eyes and he can be her legs.

I have always been really inspired by the families, especially the young kids, who are born with these conditions

Because I have been with the foundation for so long, studying the science and interviewing families, I gathered a lot of background information that way. I also talked with a couple of developmental biologists about the idea of a child being born without retinas and how feasible that was. I decided to mention that Retina Boy has some retinal tissue because in developmental biology the retina is an early part of the eye structure.

Ben Shaberman

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Growth of Ophthalmic Surgical Devices and Therapeutics (Eye Care) Market Projected to Amplify During ‘ 2018 – 2026’ – Press Release – Digital Journal

January 25th, 2020 1:46 am

This press release was orginally distributed by SBWire

Pune, India -- (SBWIRE) -- 01/23/2020 -- Transparency Market Research (TMR) has published a new report titled, "Ophthalmic Surgical Devices and Therapeutics Market Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 20182026". According to the report, the ophthalmic surgical devices and therapeutics market is expected to reach at US$ 43,794.4 Mn by the end of 2018. The market is anticipated to reach US$ 68,898.4 Mn by 2026 and expand at a CAGR of 5.8% from 2018 to 2026. Rise in number of geriatric patients, increase in awareness regarding eye disorders, and high unmet medical needs are expected to augment the global market from 2018 to 2026. The ophthalmic surgical devices and therapeutics market is projected to expand owing to an increase in the prevalence of eye-related disorders among the population, demand for better treatments, and developing healthcare infrastructure in various countries across the globe.

ophthalmic surgical sevices therapeutics marketIncreasing geriatric population and rising awareness regarding eye diseases

According to data published by the United Nations Department of Economics and Social Affairs, the geriatric population is expected to double by the end of 2050 and is projected to reach nearly 2.1 billion. This increasing geriatric population is prone to significant risk of eye-related disorders, including blindness. Public awareness regarding common eye conditions is increasing in developing countries, leading to early diagnosis and treatment of eye diseases. Furthermore, there are a large number of organizations dedicated to fight blindness, restore vision, and create awareness regarding eye health. National Eye Institute, National Association for Visually Handicapped, National Federation of the Blind, and Prevent Blindness are some eye health organizations concerned with prevention of eye diseases.

For More Details, Request A PDF Brochure Report @ https://www.transparencymarketresearch.com/sample/sample.php?flag=B&rep_id=60669

Increase in incidence rates of eye related disorders

According to the World Health Organization (WHO), there are 285 million visually impaired people globally, approximately 90% of them reside in low to middle income countries. Furthermore, approximately 95 million people suffer from cataract, and 20 million suffer from various eye conditions, including glaucoma, muscular degeneration, infections, and childhood-related conditions. Significant rise in incidence of eye-related diseases, especially in developed countries, is anticipated to drive the ophthalmic surgical devices and therapeutics market between 2018 and 2026. Patients undergoing open angle glaucoma and age related macular degeneration (AMD) in the U.S., were 2.7 million and 2.1 million, respectively. This number is projected to increase to 3.3 million and 2.5 million, respectively, by 2020. Increasing patient pool in developing countries as well as developed countries is estimated to propel healthcare spending for eye treatments in these countries and drive the ophthalmic surgical devices and therapeutics market.

High unmet needs for refractive corrections

According to an article published by the British Journal of Visual Impairment, refractive errors are the leading cause of visual impairment and at the same time, most treatable cause of visual impairment in children. Furthermore, according to this article, more than 90% of people with refractive errors reside in low-income and poor countries and cost is a major obstacle to accessing glasses and meeting the need for correction. Studies indicate that rates of willingness to pay for glasses are low, and cost and affordability is a primary reason for not using glasses in China, India, countries in Africa, and several developing countries across the globe.

Therapeutics segment dominates the global market due to its choice as first line of treatment for ocular diseases

In terms of product type, therapeutics is a highly attractive segment of the global ophthalmic surgical devices and therapeutics market, followed by surgical devices and vision care segments. This is attributable to the preference for drugs as the first line of treatment for any eye-related diseases. Expansion of the segment is primarily attributed to the increased prevalence of glaucoma and ocular infections among the population. According an article published by the American Academy of Ophthalmology, the global prevalence of glaucoma for population aged 40 to 80 years is 3.54%. The prevalence of primary open-angle glaucoma is considerably high in Africa, i.e., 4.2%, and the prevalence of primary angle-closure glaucoma (PACG) is significantly high in Asia, i.e., 1.09%.

North America dominates the global market owing to significant technological advancements in the region

North America dominates the global ophthalmic surgical devices and therapeutics market due to a large patient pool, high cost of specialty branded drugs, high cost of ocular surgeries, and increase in the geriatric population in the region. The region is estimated to maintain its dominance during the forecast period. According a U.S eye disease statistics, published by the American Academy of Ophthalmology, cataract, age-related macular degeneration, glaucoma, and diabetic retinopathy are the most common causes of visual impairment among the population in the U.S. Additionally, approximately 7.32 million people in the U.S. are expected to suffer from primary open-angle glaucoma by 2050. Moreover, rising healthcare expenditure and increasing investments are key factors that are anticipated to boost the ophthalmic surgical devices and therapeutics market in the next few years. The ophthalmic surgical devices and therapeutics market in Asia Pacific is projected to expand at a notable CAGR due to increasing awareness regarding eye diseases in developing countries and government initiatives introduced in the region.

Investments by key players is driving the global ophthalmic surgical devices and therapeutics market.

Key players dominating the ophthalmic surgical devices and therapeutics market include Allergan Plc., Johnson & Johnson Services, Inc., F. Hoffmann-La Roche Ltd., Novartis AG, Bausch Health Companies Inc., Regeneron Pharmaceuticals, Inc., Santen Pharmaceutical Co., Ltd., Carl Zeiss Meditec AG, HOYA Corporation, and Bayer AG.

For more information on this press release visit: http://www.sbwire.com/press-releases/ophthalmic-surgical-devices-an/release-1272447.htm

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Growth of Ophthalmic Surgical Devices and Therapeutics (Eye Care) Market Projected to Amplify During ' 2018 - 2026' - Press Release - Digital Journal

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Unsociable shifts and no colour blindness: Minimum requirements for 53000 Nothern train driver job – The Star

January 25th, 2020 1:46 am

Thats the salary youd get after three years of training.

But what else do you have to have in your locker to get the green light to become a driver?

Well, theres quite a few rules and regulations stipulated by Northern that mean not just anyone can jump into the cab.

The firm has a list of minimum personal requirements that you need to become a driver.

"You don't need any train driving experience to apply, said the advert.

However, we look for people who can concentrate for extended periods, with an eye for detail and a have real sense of focus about them, even in the face of rotating shift patterns.

"If you're a great decision maker who can think on your feet and approach a situation logically and in a structured way, then you're the kind of person who can keep a Northern train running on time.

And here are the minimum requirements needed - including sight and commuting

In order to become a train driver with Northern:

You must not have defective colour vision

You must be willing to work irregular and unsociable shift patterns

You must live within a 45 minute commutable distance from the location you are applying for

You must be aged between 20 and 62 years

Northern began operating the Northern franchise on 1 April 2016 and inherited units from the previous operator Northern Rail.

Its trains call at 528 stations about a quarter of all stations in the country and of these stations 476 are operated by Northern.

But the firm has also been hit by worsening punctuality, perceived poor customer service, frequent industrial action by staff and delays in introducing new rolling stock.

The future of the Northern franchise is being reviewed by the Department for Transport, with some Government officals saying it will be stripped of the service.

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Unsociable shifts and no colour blindness: Minimum requirements for 53000 Nothern train driver job - The Star

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Letter: Voters in the 27th District deserve better treatment – Buffalo News

January 25th, 2020 1:46 am

Former Republican Congressman Chris Collins lied and cheated during his term in office all the way into a 26-month prison sentence.

He was charged with wire fraud, conspiracy to commit securities fraud, securities fraud, and lying to the FBI. The evidence prior to his guilty plea was overwhelming, yet that did not prevent Collins from constantly lying that he was innocent, nor did it deter the Republican Party from re-nominating him and extolling him as a paragon of virtue and most importantly, an ardent and unwavering supporter of his majesty, and liar-in-chief, Donald Trump.

Because in the final analysis that is what the Republican Party is now all about, blindness devotion to Donald Trump, the most prolific liar and con man to ever come upon the American political scene. We will soon see the candidates to replace convict Collins on the Republican ballot tripping over themselves to out Trumpian one another in order to earn the nomination of the now cult of Trump.

Truthfulness be damned, for the nomination will go to the candidate who is most willing to abandon decency, honor, integrity and adherence to the Constitution in order to gain the blessing of the golden idol now sitting upon the throne of the presidency.

I can only pray that the voters of the 27th Congressional District will finally wake up and realize that they deserve better, that the economy can flourish without deserting all the values that have set the United States apart from the other nations of the world and that the Republican party has cheated them before and will cheat them again.

Richard Kirisits

Kenmore

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Mum fears never seeing kids’ faces again due to condition causing blindness – Somerset Live

January 25th, 2020 1:46 am

A mother-of-two from Yeovil faces the heartbreaking prospect of losing her sight within a year if she is unable to raise enough money to undergo pioneering treatment.

Jemma Jackson says the thought of no longer being able to see Oscar, 14, and Alfie, 6, has left her with a "pain like I've never known and a fear I could never have imagined".

The 32-year-old single mum has lived with type one diabetes since the age of three, but in recent years, she has developed proliferative retinopathy, a disease that can cause rapid and progressive blindness if left untreated.

The only treatment available on the NHS has been unsuccessful, leaving her needing to raise at least 5,000 to enable her to receive injections privately.

It involves injecting a chemical into the eyeball, stopping the growth of blood vessels inside the retina, with the hope of preventing sight from deteriorating any further.

Jemma said: "Any parent can relate and understand how painful the prospect of not being able to see your childrens faces ever again would be.

"Its a pain like Ive never known and a fear I could never have imagined.

"I struggle but I am able to carry on a normal-ish life with the vision I do have left.

"If I were to lose anymore, or all of my vision, I honestly dont know what I would do. The thought makes me feel sick to my stomach.

"I know I am lucky in many other ways, I should and would be blind already if it was not for the treatments Ive already had, but I am so scared at what my future might hold.

"I just really want to keep my vision for as long as possible, so I can see my kids grow up, and then my eyes can finally give up.

"Until then, I desperately want to keep fighting."

Anyone who wishes to donate to the cost of Jemma's treatment can do so via GoFundMe .

To keep up to date with our latest news, follow us on Facebook and Twitter .

For more Somerset news, like our Facebook page .

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True knowledge renews the heart – CatholicPhilly.com

January 25th, 2020 1:46 am

More than mere information, the gift of knowledge refashions the heart to love and serve God, and his people. (CNS illustration/Tyler Orsburn)

By Mike Nelson Catholic News Service Posted January 24, 2020

What is knowledge? More specifically, what is knowledge in relation to our Catholic faith?

Several years ago, I came upon St. Bonaventures Prayer for the Seven Gifts of the Holy Spirit. A 13th-century cardinal and follower of St. Francis of Assisi, St. Bonaventure is also a patron saint of our parish, Mission San Buenaventura in Ventura, California, where my wife directs music and liturgy and I play piano.

Reading this prayer inspired me to set St. Bonaventures prayer to music, in which I combined two gifts to make part of a verse: Grant us courage, grant us knowledge, so we may know and protect what is good.

The actual words of St. Bonaventures prayer suggest I was, hopefully, on the right track: May he impart to us the gift of knowledge, which will enable us to discern your teaching and distinguish good from evil.

Knowledge can be a tricky quality (or gift, if you will) to assess. Many of us have heard that it doesnt take an active Catholic to know what the Catholic Church teaches. Inactive Catholics, non-Catholics and even atheists can be just as knowledgeable about Catholic teaching as those who practice their faith in some cases, more so.

The key, of course, is taking to heart what we know and acting on it. Or, as bishops instruct diaconate candidates during the rite of ordination: Believe what you read, teach what you believe and practice what you teach.

That, in the context of our Catholic faith, should give us a clue as to what knowledge actually means. Knowledge simply for knowledges sake, St. James suggested rather pointedly, means nothing without action inspired by that knowledge: What good is it, my brothers, if someone says he has faith but does not have works? (Jas 2:14).

As an adult, I attended confirmation preparation classes at another parish (it was a pre-RCIA preparation process), designed to teach us facts about the faith I would profess at the Easter Vigil. We even took a midterm to test our knowledge.

Fortunately, I was already of the mind to become Catholic, not because of its teaching but because I was seeking a community of faith that sought to know and follow Jesus Christ. The words I once heard during a parish retreat, We are the body of Christ, we are a community of believers, and the ministries that serve church and community in Jesus name, are why I became and remain a Catholic.

This was long before I knew anything about St. Bonaventure or any of the saints, or anything about the Catechism of the Catholic Church, or very much about Scripture. But I learned very quickly about the person of Jesus, and how he was more interested in how people lived their lives than in how much they knew.

(Related: Discerning a path with the gift of knowledge.)

The Pharisees knew all too well how Jesus felt about learned people. When he healed the man born blind, the Pharisees were outraged that Jesus had performed his healing work on the Sabbath, in violation of the law.

And, believing that blindness was a result of sin, they were outraged further when Jesus suggested that blindness was more than a physical affliction.

If you were blind, Jesus told the Pharisees, you would have no sin; but now you are saying, We see, so your sin remains (Jn 9:41).

The blind man, now healed, understood as well as anyone that knowledge of Jesus, and his message to heal and serve those most in need, leads to hope for all, and calls us into action to meet those needs.

For if knowledge impacts only the mind and not the heart, what is its purpose? As St. Paul told the people of Ephesus, May the eyes of your hearts be enlightened, that you may know what is the hope that belongs to his call (Eph 1:18).

St. Thomas Aquinas a doctor of the church like his contemporary, St. Bonaventure suggested in Summa Theologica that all gifts of the Holy Spirit are very much connected to the cardinal virtues rooted in ancient Greece and later proclaimed by church leaders in the Middle Ages.

The gift of knowledge, St. Aquinas said, corresponds to the virtue of hope, which better helps us to understand the meaning of God.

God desires all men to be saved and to come to the knowledge of the truth: that is, of Christ Jesus, declares the catechism (No. 74). Christ must be proclaimed to all nations and individuals, so that this revelation may reach to the ends of the earth.

It is important, too, to realize that, as St. Bonaventure (inspired by Isaiah, St. Paul and others) proclaimed, there is a relationship between knowledge and the other gifts of the Holy Spirit.

If you receive my words and treasure my commands, turning your ear to wisdom, inclining your heart to understanding; yes, if you call for intelligence, and to understanding raise your voice; if you seek her like silver, and like hidden treasures search her out, then will you understand the fear of the Lord; the knowledge of God you will find. For the Lord gives wisdom; from his mouth come knowledge and understanding (Prv 2:1-6).

***

Catholic journalist Mike Nelson writes from Southern California.

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People of Determination at Syrian refugee Mrajeeb Camp in Jordan provided with psychological support – Jordan – ReliefWeb

January 25th, 2020 1:46 am

ABU DHABI, 23rd January, 2020 (WAM) -- The Zayed Higher Organisation for People of Determination, ZHO, launched the initiative, "Bridges of Hope to Support People of Determination", in cooperation with the Emirates Red Crescent, ERC, for the Syrian refugee families of People of Determination at the Mrajeeb Camp in Jordan, as part of the ZHOs efforts to support People of Determination in foreign countries by collaborating with the ERC'S initiatives and projects.

The initiative aims to provide 148 families of Syrian "refugees with determination" guidance to mitigate psychological pressures and stress and provide families with background information, practical training sessions, and psychological and social counselling.

Abdullah Abdulaali Al Humaidan, Secretary-General of ZHO, who accompanied the ZHOs team, stated that the organisation had launched the initiative under the guidance of the wise leadership, as well as the supervision and concern of H.H. Sheikh Khalid bin Zayed Al Nahyan, Chairman of the Board of Directors.

Al Humaidan extended his appreciation to the ERC, headed by H.H. Sheikh Hamdan bin Zayed Al Nahyan, Ruler's Representative in Al Dhafra Region, and to all the employees there for their genuine and fruitful cooperation with the ZHO. He also thanked the Ministry of Foreign Affairs and International Cooperation and its minister, Abdullah bin Zayed Al Nahyan, as well as the UAE Embassy in Jordan for supporting this initiative and collaborating with the ZHO. He finally thanked the parents at the Mrajeeb Camp for joining the initiative, as well as the ZHOs employees.

Ahmed Ali Al Balushi, UAE Ambassador to Jordan, received Al Humaidan and the accompanying delegation as part of the delegations visit to the Kingdom of Jordan to implement the initiative and praised the delegations efforts and the wonderful humanitarian initiative for the People of Determination.

Moza Ahmad Al Salami, Director of ZHOs Al Ain Autism Centre and the head of the team, said, "This initiative was launched in collaboration with the ERC after signing a cooperation agreement with the ZHO. The team includes Moza Ahmad Al Salami, initiatives coordinator and supervisor; Ghadeer Al Oteibi, senior social worker; Anoud Al Hajri, psychologist; Sheikha Salem Al Kabi, specialised teacher, and Ahmad Al Zoghbi, specialised teacher."

She added that 148 families were part of the initiative, including those suffering from cases of Autism Spectrum Disorder, intellectual disabilities, physical impairment, deafness, and blindness and Down syndrome.

Moza Al Salami revealed that a team of staff members had created a sensory room called the "Bridges of Hope Initiative Room to Support People of Determination", where the staff was trained by a specialist in special educational needs from the camp on how to best utilise the room to serve families and people of determination.

Al Salami pointed out that the initiative is aimed at providing participants with skills to help them lead independent lives, acquire appropriate habits, and protect themselves.

This is in addition to helping children develop different intellectual skills and language capabilities and teaching them to rely on themselves, acquire appropriate eating habits, and inculcate major and minor life skills and kinetic synergy capabilities.

WAM/Rasha Abubaker

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People of Determination at Syrian refugee Mrajeeb Camp in Jordan provided with psychological support - Jordan - ReliefWeb

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Email accessibility is crucial: here’s how to get it right – Global Banking And Finance Review

January 25th, 2020 1:46 am

By James Hall, Commercial Director, Striata UK

While most people understand the importance of making the physical world as accessible to as many people as possible, including those with disabilities, digital accessibility is less well-regarded but equally important. And while a lot of ground has been covered with regard to the websites, attention is now slowly turning to email.

Much time is spent designing, developing and testing emails to ensure they render correctly on different screen sizes and in the most commonly used email clients, to provide a good email experience. Not enough attention is paid, however, to ensuring people who have disabilities are able to consume these emails.

To put that into perspective, according to the World Health Organisation, at least 2.2 billion people globally have a vision impairment, which ranges from needing glasses to total blindness. Thats more than the total user base of Gmail (1.5 billion) and logically would make up a significant portion of the 4 billion email users, worldwide. Why should there be any less effort spent on them to ensure an email renders well on the assistive device they use.

But what does email accessibility look like and how can you ensure that your emails are as accessible as possible?

What is email accessibility?

Email accessibility is the practice of making an email easy to read for as wide an audience as possible, including those with visual, auditory, motor or cognitive disabilities. Email accessibility is an important part of User Experience (UX) and applying accessibility principles will result in the best possible experience for all users.

There are a number of assistive technologies that help people with disabilities access the web and email. These include screen readers (used by people with visual impairment, mobility limitations and learning disabilities), which read the content of a screen aloud using text-to-speech, and screen magnifiers (used by people with low or partial vision) which enlarge a portion of the screen so that the content is readable.

Content

Most email writers already know the importance of ensuring that the content has a logical flow, and the message is easy to understand. This becomes more important when one considers how email will be read by a visually impaired person or anyone with cognitive disabilities such as dyslexia.

So, for example, subject lines should be short and to the point in order to perform best when read aloud through a screen reader. Language should be similarly clear and concise. Rather use simple words and language making it easier to understand for both those with cognitive difficulties, as well easier to understand when read through a screen reader.

For the same reason paragraphs should be short and well structured, and long lists and tables should be avoided.

Designing for accessibility

Layout and design accounts for a large part of how accessible an email will be, from color, font size and font choices, to the way images are treated. As with design for different screen sizes, there are guidelines for designing emails that are suitable for screen readers and magnifiers.

Making judicious use of whitespace around paragraphs, bulleted copy and images is not only good for accessibility, it makes skim-reading easier too. Another important factor when designing for accessibility is color, especially for users that are color blind. Blue is a good color to use, because it is not affected by red and green color blindness.

There should also be adequate contrast between the text and background color of your call to action buttons, and links should be prominent and easy to click.

HTML Developers

Understanding how an email is read using a screen reader and how it appears using a magnifier is something all HTML coders should know.

Some basic guidelines include using heading styles in logical sequence (making it easier for someone using a screen reader to navigate by sections), limiting the animation to 3 seconds in animated gifs, avoiding tables, and cutting back on the use of multiple spaces in your code as a screen reader will read these out loud as blank.

Testers

Whilst an email is often tested across all major device types, screen sizes, and email clients, its worth making the extra effort when it comes to accessibility.

Fortunately, there are tools that make this easier. For example, some email testing platforms such as Litmus and Email on Acid now offer accessibility testing features as part of their service.

Even with the use of these tools, however, one should still test email with images off to see how readable it is for people who dont see the images (for whatever reason). Check the flow of information and whether the essence of the message is conveyed, even if no images are present. Additionally, skim-read the email in a few seconds as this is how most people read online.

Worthwhile effort

While ensuring that your emails are fully accessible does take effort, there can be no denying that its worth the investment.

Most of the work required to ensure that blind people and those with visual impairment can access your emails is in line with email best practice.

The overall email experience, therefore, wont just be improved for customers with disabilities but for everyone.

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Email accessibility is crucial: here's how to get it right - Global Banking And Finance Review

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Visual Perception in Congenitally Blind Adults – Duke Today

January 25th, 2020 1:46 am

Vision provides a rich source of information that most peoples lives revolve around. Yet, for blind people, how do they conceive of visual intake and what happens to regions of the brain dedicated to vision if a person doesnt have typical visual input? These are questions that drive Marina Bedny PhD, an Assistant Professor of Psychological and Brain Sciences and principal investigator of a neuroplasticity and development lab at John Hopkins University.

Bedny spoke at Dukes Institute for Brain Sciences on Friday, January 17th, about her work with congenitally blind adults. Her lab explores similarities and distinctions of visual perceptions between blind and seeing people and seeks to understand how nuanced, natural variation in experience shapes the human mind and brain.

Many of the studies Bedny discussed have very important linguistic components. In one trial, she investigated the meaning of verbs pertaining to light events and visual perception as compared to touch, amodal, auditory, and motion verbs.

Both blind and sighted people displayed nearly identical results when comparing the different types of verbs used in the study. This showed that there were no differences in what blind people knew about the terms. Analysis of the verbs revealed that linguistic dimensions of intensity and instability were used to evaluate the words comparative meanings. Blind people agreed more on the comparison of sound emission and touch perception words. This shows that blind participants have more aligned comprehension of the meanings of other sensory terms compared to sighted people.

In other cases, Bednys lab assessed what blind individuals know about color. One study used three object types natural kinds, functional artifacts, and non-functional artifacts. These categories were used to evaluate agreeance not only on color, but the relevancy of color to certain objects functions as well.

Another crucial question of Bednys work looks at how the innate structure of the brain constrains cortical function. The findings show that the visual system in blind participants has been repurposed for higher cognitive functions and that portions of the visual system connected to high cognitive abilities are invaded by the visual systems. Along with repurposing visual regions for linguistic use, Bednys lab found that visual regions of the brain are active during numerical processing tasks too.

Blind people display additionalactivity in the visual centers of their brain in numerous studies beyond havingthe same regional brain responsiveness as sighted people. Though furtherresearch is necessary, Bedny proposes that there is a sensitive period duringdevelopment that is critical to the specialization of the brain. Study participantswho have adult-onset blindness do not show the same sensitivity and patternedresponses in visual cortices repurposed for different functions as congenitallyblind subjects.

At birth, the human cortex is pluripotent providing the best of both worlds, Bedny said. The brain is prepared but highly flexible. Her studies have repeatedly shown that the brain is built for and transformed by language, and they underscore the importance of nature and nurture in human development.

Post by Cydney Livingston

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Sepsis has tripled in Australia and these small caps are tackling it head on – Stockhead

January 25th, 2020 1:44 am

With triple the number of sepsis cases in Australia, small cap biotech company Cynata Therapeutics (ASX:CYP) hopes to wage a new war on blood infections.

Last Friday the world learned blood infections were on the rise, with researchers showing in the international medical journal The Lancet that sepsis infections had increased 201 per cent Down Under.

Young children, the elderly, indigenous or those with compromised immune systems are at risk of sepsis.

Lancets Global Burden of Disease study of 195 countries and territories was based on records such as Australian death certificates, rather than just what medical professionals put on their paperwork, and showed a dramatic increase in cases from previous estimates.

The study showed that in 2017 there were about 55,000 cases of sepsis in Oz more than three times the number of cases than the 18,000 incidences previously estimated.

The death count that year from the infection was 8,700 people in Australia. It was a dramatic 74 per cent increase on the 5,000-deaths estimated previously.

Some people experience multiple cases of sepsis in a year but mortality rates are still grim.

A 2016 study by the Canadian Institute for Health Information and the Canadian Patient Safety Institute found that the mortality rate for sepsis was 20 to 30 per cent in Western nations.

Sepsis is a life-threatening blood infection that people can rapidly lose their lives to.

Its a threat taken seriously in medical facilities across the globe, and a challenge Cynata hopes to address with stem cells to put peoples immune response in check.

Cynata researchers have shown its Cymerus mesenchymal stem cells (MSCs) can work well in battling blood infections in animals.

The company wants to expand its research to human studies, Cynata managing director and CEO Dr Ross Macdonald told Stockhead.

The recent feature article in the highly respected medical journal The Lancet and the worldwide media attention it garnered outlines the chilling reality of just how devastating, prevalent and widespread sepsis is, Dr Macdonald said.

It is now acknowledged as one the most common and lethal conditions faced in medicine and which existing treatments are not capable of addressing.

Cynatas very promising findings in the recent pre-clinical study of its Cymerus mesenchymal stem cells provide a new potential treatment option for this exceedingly challenging problem.

Cynatas early-stage research out of Ireland effectively showed its stem cells calm down the animals immune system, Macdonald explained.

Known as the silent killer, sepsis is seen by some as an overreaction of the immune system to infection.

The Lancets study found the number of cases of sepsis worldwide had doubled to 49 million a year.

Deaths from the condition stood at 11 million people, equating to one in five deaths globally.

Researchers called it the leading cause of death worldwide.

Australian Sepsis Network (ASN) founder Professor Simon Finfer from The George Institute for Global Health was one of The Lancet studys authors and said it was concerning so many lives were lost to a largely preventable condition.

People need to act fast with sepsis, which can quickly damage a persons tissues and organs and lead to shock, organ failure and death.

Australia has good systems in place to treat people early but more needs to be done, according to Professor Finfer.

We urgently need a coordinated national approach that addresses pre-hospital and in-hospital recognition and treatment, to address the significant death and disability caused by sepsis in Australia, he said.

ASN is housed at the George Institute and has $1.5m in federal government backing to develop treatment guidelines and run public awareness campaigns.

Current treatments can include antibiotics given within an hour of medics suspecting sepsis, intravenous fluid therapy, vasopressordrugs to support organ systems, mechanical ventilation and renal replacement therapy.

More females than males experienced sepsis, while 40 per cent of cases are in kids.

The most affected regions worldwide are sub-Saharan Africa, the South Pacific islands near Australia and South-East Asia.

Cynata is not the only ASX-listed company looking at sepsis.

Recce Pharmaceuticals (ASX:RCE) has an antibiotic known as RECCE 327 that targets sepsis and blood infection.

The company raised about $7m last October to progress the drug through early stage clinical trials to test its safety and work out the right doses.

Medtech Uscom (ASX:UCM) is targeting the monitoring market with a non-invasive medical device to measure heart flow that can be used in sepsis patients.

Resources company Surefire Resources (ASX:SRN) had a sepsis program that it licensed from the University of Western Australia in the mid-naughties, when it was known as Genesis Biomedical (ASX:GBL).

Genesis opted to terminate the program in 2006 and become Black Ridge Mining (ASX:BRD) before rebranding to Surefire.

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The North America genome editing market is expected to reach US$ 4,148.1 Mn in 2025 from US$ 1,234.5 Mn in 2017 – Yahoo Finance

January 25th, 2020 1:43 am

The market is estimated to grow with a CAGR of 17. 2% from 2018-2025. The growth of the genome editing market is primarily attributed to the rise in the production of genetically modified crops and rising prevalence of the genetic diseases.

New York, Jan. 24, 2020 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "North America Genome Editing Market to 2025 - Regional Analysis and Forecasts by Technology, Application End User, and Country" - https://www.reportlinker.com/p05774528/?utm_source=GNW However, the stringent regulatory framework and limitations in genome editing are likely to pose a negative impact on the market growth.

On the other hand, emerging markets for precision and regenerative medicines is likely to have a positive impact on the growth of the North America genome editing market in the coming years.The genome editing has proved itself to be the most promising way of feeding the fast growing population across the world.The changes in the climatic conditions due to the global warming and others conditions such as droughts floods are witnessed more across the world.

Therefore, the feeding the rising population is question among the people across the world.Due to the genome editing the concerns are being reduced to a great level, the two types of the genetically modified crops are widely grown.

Firstly, these crops are altered in a ways that they are not affected by the herbicide glyphosate.Secondly, crops are produced to protect themselves from the insecticides.

The advantages of the genetically modified crops includes diseases resistance, improvement of the photosynthesis, improvement of the nutrition, and more. The genetic modification helps to enhance the productivity without hampering the health of the crops. In addition, for the genetically modified crops the limited resources are required and it require less or no pesticides for its growth. The time required for the growth of the genetically modified crops is less, therefore these are highly preferred crops in the western world. The demand for the genetically modified crops is rising in the eastern region due to the benefits offered by these crops.According to the International Service For The Acquisition Of Agri-Biotech Applications (ISAAA), 2017 statistics, 19 developing countries have planted 53% which is approximately to 100.6 million hectares of the global biotech hectares, whereas the 5 industrial countries have took the 47% which is near about 89.2 million hectares share. The trend of growing genetically modified crop is expected to grow in the coming future.In 2017, the CRISPR segment segment held a largest market share of 53.6% of the genome editing market, by technology. This segment is also expected to dominate the market in 2025 owing to the simple, fast and accurate property of the CRISPR. Moreover, the TALENs segment is anticipated to witness the significant growth rate of 17.1% during the forecast period, 2018 to 2025 owing to the properties provided by the TALENs the market for it is expected to rise in the coming near future.North America genome editing market, based on application was segmented into genetic engineering, cell line engineering and others. The cell line engineering segment is anticipated to grow at a CAGR of 18.0% during the forecast period. Moreover, the genetic engineering segment is expected to grow at the significant rate during the coming years owing to its sub segments such as animal genetic engineering and plant genetic engineering that are being carried out extensively. In 2017, the biotechnology & pharmaceutical companies segment held a largest market share of 61.2% of the genome editing market, by end user. This segment is also expected to dominate the market in 2025 owing to the advantages of the CRISPR, the companies have enhanced their research and development for the drug discoveries that can treat various diseases. Hence, the market is likely to propel in the coming years.Some of the major primary and secondary sources for genome editing included in the report are, Contract Research Organizations (CRO), United States Department of Agriculture (USDA), National Institutes of Health (NIH), Abu Dhabi Fund for Development (ADFD), Ministry of Science and Technology (MST), International Service For The Acquisition Of Agri-Biotech Applications (ISAAA), Food and Drug Administration (FDA), Department of Biotechnology (DBT) and others.Read the full report: https://www.reportlinker.com/p05774528/?utm_source=GNW

About ReportlinkerReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

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The Most Expensive Materials on Earth – 24/7 Wall St.

January 25th, 2020 1:43 am

On a daily basis, we interact with hundreds or thousands of materials that range in complexity from the water we drink to the OLED screens on our smartphones. The development of new materials can be linked to nearly every major advance in human history, and breakthroughs made by material scientists have profoundly affected our society and daily lives from transportation to how we receive information.

Some of the most expensive materials on this list are naturally occurring, while others, such as two-dimensional materials, have been developed in laboratories and are on the cutting edge of scientific progress.

Human epochs are defined by the materials that enabled advancement, First the Stone Age, then bronze, then iron, then steel, then plastics, and now were firmly in the semiconductor age, said Alex Kozen, an assistant research scientist at the University of Maryland, College Park. I expect the next great advance in materials to be biological materials, where genetic engineering could be used to create organisms that provide better nutrition, grow structural materials and much more.

The following is a list of some of the most expensive materials used today in manufacturing, tech products, research, and other applications. They include precious metals, compounds, rare earth elements, and ultra-thin two-dimensional materials.

Click here to see the most expensive materials on Earth

The cost of different materials is determined by several factors, including supply and demand, mining costs, raw materials costs, how rare or abundant a material is, purity of the material, engineering costs whether it is a complex material to produce among many other factors. The materials on this list are not meant to represent a complete list of every expensive material. The materials on our list were selected in part because they are used commonly in industry and research.

To compile our list, we used various scientific journals, the Defense Logistics Agencys list of Strategic Materials, the USGSs Mineral Commodities Summary 2019, and prices were estimated from various suppliers websites.

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Vertical farms of the future require genetically edited plants, says scientist – FoodNavigator.com

January 25th, 2020 1:43 am

The impending need to feed almost 10 billion people by 2050 is fuelling innovation in the agri-food sector.

Vertical farming is one such example. Tipped to play an increasingly important role in global agriculture, plant factories as they are otherwise termed are vertically-stacked, fully controlled environments used to produce food.

The technology has been praised for its potential to help societies meet elevated demand for food, without the need for additional farmland.

Analysts appear similarly persuaded. According to Global Market Insights, the vertical farming market is expected to expand by 25% by 2024, to reach a value of 11.4bn.

However, feeding growing populations with vertical farms, and using the same seeds and plants used in conventional agriculture today to do so, demonstrates a lag in innovation, suggests Aberystwyth Universitys Professor Huw Jones.

Vertical farming technologies are advancing, and fast. Today, it is possible to automate a number of processes in urban agriculture, including the sowing of seeds, and monitoring of LED lighting.

Climate including temperature, humidity, and CO levels can also be controlled externally, and machine learning can be leveraged to help save electricity and water use.

In order to get the most out of urban agriculture innovations, plant technology will have to similarly advance, said the professor of translational genomics for plant breeding at the Westminster Food & Nutrition Forum last week in London. The kinds of plants that we are going to ultimately have in [plant factories] are not going to be the same kind of plants that we have in soil.

We have huge innovation in hydroponic vertical farming, the professor continued, but we are still using the old seeds. What we are lacking, therefore, is the plant architecture itself, he stressed.

Professor Jones does predict this will change, but it will require gene editing to do so.

Greater understanding of DNA sequencing and genome editing, alongside reduced costs in gene sequencing, has helped to encourage interest in plant technology, he explained.

Plant-specific transcription factors, for example, have garnered much attention in food science. Transcription factors are genes that control the transcription of other genes in fruit and vegetable colour, texture, and aroma, we were told.

As a result, scientists can alter the colour of tomatoes, or the smell of fruits, he continued. We can make completely new fruits by harnessing these genes that control genes [with] these MYB transcription factors.

In vertical farming, gene sequencing could also help bridge the technology gap between vertical farming and plant architecture.There is a lot of research underpinned by the understanding of the gene sequence. We understand how to change the internode length of these sorts of plants. [We know] how to change the fruiting patterns, so that we can make plants that are much more suitable to those kinds of new agricultures.

In Europe, the scientific community regularly voices its support of genetic technologies. Both conventional genetically modified organisms (GMOs) and genetic editing tools such as CRISPR/Cas have been praised for their potential to help develop more robust crops in the face of climate change.

Genetic editing using CRISPR/Cas technology involves removing part of the genetic code, as opposed to GMO methods, which uses genetic engineering to insert new code.

However, EU regulation has put Europe out of step with the rest of the world, argued Professor Jones, particularly in countries where very simple genome editing falls outside of their GMO legislation.

Here, the professor is referring to the European Court of Justices (ECJ) July 2018 ruling. According to its decision, crops obtained by mutagenesis are classified as GMOs in Europe, as the techniques and methods of mutagenesis alter the genetic material of a plant in a way that does not occur naturally.

Describing this legislation as too heavily politicised to onboard biotechnology, Professor Jones suggested the UKs impending departure from the EU could present an opportunity for the sector.

This is an area that the UK, post-Brexit, could look at to really rationalise the regulation of mutation breeding, he said. That has always been outside the GMO scope. And to think about simple genome editing where that is synonymous with old mutation breeding techniques and also to exclude that.

In the case that such editing, which in the future may fall outside of GMO legislation, produces a novel food, the professor agreed it should be categorised by novel foods legislation.

In any case, Professor Jones is convinced that over the next ten years, there will be significant innovation in food biotechnology. Some of which, wont fall neatly into novel food or biotechnology regulations. So, I think we have some interesting times ahead to see how these things are going to be regulated.

Continued here:
Vertical farms of the future require genetically edited plants, says scientist - FoodNavigator.com

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