StemCell Therapy

Every fall is not the same, but similar. It is a good time to pick up businesses having longevity, and ride through this volatility. But, investors cannot expect to reap benefits immediately as markets don't like uncertainty, Hemang Kapasi, Portfolio Manager Equity Investment Products, Sanctum Wealth Management, said in an interview with Moneycontrols Kshitij Anand.

Edited excerpt:

Q) Indian market snaped two-weeks of positive close and turned negative. What led to the fall on D-Street especially when it started off on a bullish note?

A) If one does an analysis of equity market performance for the last one month, all the major world equity market indices are in positive territory from ~5-15 percent.

Investors worldwide turned euphoric about the resumption of economic activities as lockdowns are being lifted across the world supported by stimulus packages by the governments and liquidity pumped in by the central banks.

Even Indian equity markets participated in this rally with gains of about ~11 percent in the last one month. Post a sharp up move in the equity markets world over, and just before the FOMC meeting, investors were seen booking profits ahead of an important event, and Indian equity markets were no exception.

A) Going forward, equity markets would be a function of economic recovery and sustained liquidity support provided by central banks to support financial markets.

As India is still coming out of lockdown and if one goes by forecasted negative GDP growth for the year, then we are likely to be trading on the higher range on indices.

A) Lockdown would not be a solution as the pandemic is here to stay for some time till the vaccine is found. Lockdown can be used to create health infrastructure, but it cant contain cases as seen in this lockdown.

Lockdown impacts the whole economy and impacts each and every one. Governments, Corporates, and individuals will have to work around this taking precautions and move ahead as economic implications are far more severe if lockdown is implemented

A) As a lender of last resort, theGovernment has to take measures to support the economy. To predict the manner in which it can be implemented is a futile exercise, governments have to step up to revive demand when the need arises.

A) With equity markets having a big up move in the last one month, there is some positivity seen in mid & small-cap space. Having said that they are still down 22 percent from their 1 year high and 32 percent down from their all-time high in December 2017

A) Financials are a place of uncertainty for the next 6 months. In the coming days they might be struggling on both topline and bottom-line.

Credit growth pick-up might take a bit of time to pick up as banks have become risk-averse to lending in these uncertain environments and on the other hand they will have to deal with rising NPAs related provisions.

Thats the reason the financial sector is among the worst-performing sector in the last 3 months, having said that any improvement in the above two-aspect will lead to huge re-rating for this sector.

A) Its true, history may not repeat but it does rhyme. Every fall is not the same but similar. It is a good time to pick up businesses having longevity and ride through this volatility. But, investors cannot expect to reap benefits immediately as markets don't like uncertainty.

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'Good time to invest in firms having longevity, but don't expect returns immediately' - Moneycontrol.com

Years ago sometimes it seems like eons ago I wrote a book and did a PBS special titled The Longevity Code: Your Personal Prescription for a Longer, Sweeter Life.

I learned a lot about writing a book. If youve never had this experience, let me clue you in its not that easy. When youre done, you realize you learned so much that youd like to change the whole thing and start over again.

The problem is you have the publishers deadline. Crown Publishing, an imprint of Random House, had its deadline for my book, so out the door it went.

In that book, I postulated there were five spheres that affect our wellness: physical, mental, family/social, spiritual and material. I thought and still do think these are ways you can organize your life space, learning what you need to do to improve your longevity, keep robust and healthy and avoid disease and disability.

Its kind of like buckling your seat belt. Taking action reduces risk but doesnt eliminate it.

I put physical first because I am first and foremost a doctor using science and medicine to guide my judgment but realizing they dont have all the answers. Some of those whether or not youre happy or sad, pleased with your life or not might not be up to science at all. Thats why life balance and the other four spheres are so important.

Now that were dealing with social distancing, I am starting to realize perhaps I have been wrong in my analysis the social sphere should come first.

When lecturing, I like to pepper my talk with stories and jokes. Thats the only way to keep an audience on task; anecdotes help us emote.

When I get to the social sphere, I often say, Why go to the gym to get the best body you can if you dont have someone to share it with? Its a cute, trite thing to say and usually gets a laugh.

But, truth be told, I see now with the latest isolation situations that we crave our social connections. Yes, we have phones, FaceTime, etc., but the lack of in-person contact comes with a cloud that seems to hang over all of us.

We want these connections with others more than ever now that we must keep them at a distance.

Getting together with friends and family, exchanging ideas and checking in with others are critical to our health. When I have patients who retire, I always ask them how its going. Often, they say they dont miss the job, but they do miss seeing their co-workers.

Social connectedness gives us pleasure, influences our health and motivates us to take action for ourselves and others.

A recent study of more than 300,000 people showed that a lack of strong social relationships could increase death by up to 50% which is about the same as smoking half a pack a day.

So why is this so important? Ive read about this for more than 20 years and have distilled what I think are the most salient points.

Being connected gives us joy and pleasure because we are incredibly social. In the book Sapiens: A Brief History of Humankind, by Yuval Noah Harari, the author postulates that the reason Homo sapiens took over from other humanoid species was our ability to form social relationships and engage in cooperative behavior.

My spin: During this time of physical distancing, its critical to use all the electronic tools we have to stay connected it benefits our health. As we come out of hibernation from winter and look to resume connecting in our usual physical way, we now need to take a little bit different action.

Handshakes, fist bumps and high fives will return. And those hugs from friends and family that make us feel so good will feel even better when we get to share them once again. Stay well.

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Dr. Zorba Paster: Pandemic helps doctor realize our social spheres of prime importance to our health - The Spokesman-Review

Its an undeniable truth that aging is inevitable. Or is it? What if almost everything we have been taught about aging is wrong? What if we could change how long we live? In other words, could we choose our lifespan? David Sinclair, a Harvard professor, medical researcher and author of Lifespan, was recently a guest on the Aspen Brain Lab expert series. He explained to host Dr. Marc Hodosh why he believes we can really influence our longevity.

Sinclair explained that aging is a disease. Aging should be redefined as a medical condition and approached as a disease both causing fragility and often death.

The reality is aging is the root cause of most of the planets suffering and kills 100,000 people every day. Sinclair believes that when we come to this realization, then we will be able to address aging more productively.

The statistics show that the age of our community is rising, especially in the developed world. In 2017, one in eight people worldwide was aged 60 or over. In 2050, older people are projected to account for one in five people globally. So by 2050, this group will be around two billion.

An individuals lifespan is linked to lifestyle factors, more than genetics. In fact, science reveals that your lifespan will be determined by your lifestyle accounting for up to 70% Genetics will determine only 30%.

Sinclair told Hadosh that individual diseases occur in the minority, and aging to the majority. So why arent we taking aging far more seriously than we are currently? he questions.

He believes there is a need for more international attention to social, economic and political risks as well as the benefits of a world in which billions of people can live much longer and much healthier lives.

Sinclair explained that ones chronological age (the number of times weve travelled around the sun) is not the same as our biological age (how our cells have changed over that same period of time). He defines the nine different hallmarks of aging :

Like many other scientists involved in the study of aging, Sinclair believes we need to approach aging from a preventative health perspective over ones lifespan. This is a more cost-effective approach than addressing acute symptoms of the disease later on in life, he told Hadosh.

And hes pretty optimistic that science may soon have the tools to put this disease into remission.

During the discussion Sinclair spoke about the importance of hormesis and its role in lifespan and the aging process. The application of hormesis in aging research and interventions is becoming increasingly attractive and successful. The reason for this is that the research conducted over many years, is showing that mild stress-induced activation of one or more stress response (SR) pathways, and its consequent stimulation of repair mechanisms, is effective in reducing the age-related accumulation of molecular damage.

Hormesis is the what doesnt kill you makes you stronger type of stress. Stress is the disruption of homeostasis, or your bodys state of equilibrium. In fact, your body thrives on occasional stress or toxin exposure, and responds by ramping up growth and repair to bring you back to balance. Thats hormesis your bodys positive response to minor stressors. Over time, you can use hormesis to build an adaptive stress response, where you learn to benefit from sources of stress.

With exercise, for example, you need to exert your muscles, otherwise your body wont build them back stronger. Also your brain needs to be challenged. You can do this by learning a new language, or doing something creative. Its important to continually build new connections between brain cells. You can even stimulate new collagen growth in your skin with lasers and microneedling both of which cause micro-injuries. Sitting in a sauna, followed by a cold shower is also another simple way to practice hormesis.

Sinclair believes youthfulness can also be reset in the body using epigenetic reprogramming. Soon we will be able to tweak cells in a particular way that the central nervous system behaves as if it were young again.

The central nervous system is one of the first body tissues to lose regenerative capacity. His research group was able to show that the expression of 3 specific genes in mice was able to reset youthful gene expression patterns. Promoting regeneration following optic nerve crash injury also restored vision in a mouse model of glaucoma.

The group also concluded that old tissues retain a faithful record of youthful information that can be accessed for functional age reversal.

This is an exciting moment in time for the science of longevity. Researchers are on the verge of understanding the process of aging and how to create drugs that promote extended healthy longevity.

Some may argue that humans and mice are not the same, so we shouldnt get overly optimistic about these studies. However, without a doubt the work being done in their laboratory at Harvard Medical School is forward thinking and may well be lifechanging. As Sinclair attests, This is the golden era of genetics. Anything is possible. We are only limited by our imagination.

We took a look at how Sinclair is approaching his own lifespan? While hes written a lot on the subject, these 4 lifestyle interventions to improve the way we age offer a good summary from the scientist.

Sinclair says if there is one lesson weve learned this past decade it is this: aging is malleable. He has made certain changes in his own life to give himself a decent shot at having a long, healthy life.

We all need to be pushing ourselves, physically, especially as we get older and yet, Sinclair says, only 10 percent of people over the age of 65 do. The good news is that we dont have to exercise for hours on end. People who run four to five miles a week (for most people, thats an amount of exercise that can be done in less than 30 minutes every other day) reduce their chance of death from a heart attack by 40 percent and all-cause mortality by 45 percent. Thats a massive effect.

Youll know you are doing vigorous activity when it feels challenging. Your breathing should be deep and rapid, you should sweat and be unable to say more than a few words without pausing for breath. This is the hypoxic response, and its great for inducing just enough stress to activate your bodys defenses against aging without doing permanent harm.

David Sinclair believes theres nothing revolutionary about fasting. As far back as Hippocrates, the ancient Greek physician, doctors have been espousing the benefits of limiting what we eat. This is not the same thing as malnutrition. This is when the systems of our bodies begin to prey upon one another. But allowing our bodies to exist in a state of want is unquestionably good for our health and longevity.

Increasingly, research is showing through studies that reducing food availability over a lifetime has remarkable effects on aging and lifespan of animals, so most likely will on humans too.

Sinclair is a firm believer in the benefits of intermittent fasting, citing numerous studies pointing to the health benefits of intermittent fasting. In one such study, participants ate a normal diet most of the time, but five days a month ate a restricted diet. In three months, those who maintained the fasting mimicking diet lost weight, reduced their body fat and lowered their blood pressure, too. Participants also had lower levels of a hormone primarily made in the liver called insulin-like growth factor 1, or IGF-1. Mutations in the IGF-1 and IGF-1 receptor genes are associated with lower rates of death and disease.

So how does Sinclair do it? My blood sugar rises in the morning and I am not hungry. So I skip breakfast, except for two tablespoons of homemade yogurt. I try to skip lunch or eat a late lunch of a small soup or salad. At dinner I eat a normal dinner, with a focus on plant-based foods. I do not overeat. My downfall is alcohol. I often have a glass of wine for dinner a few times a week.

According to this aging specialist, the bottom line is that there is no best diet. What works for someone may not work for another. We are all different. With different ages, circadian rhythms, jobs, body compositions, microbiomes, stresses, and wants. No matter what you do, a little fasting goes a long way.

Even eating certain plants will make a difference, suggests Sinclair. Health-promoting molecules are produced in abundance by stressed plants. Sinclair explains that we get resveratrol from grapes, aspirin from willow bark, metformin from lilacs. We obtain epigallocatechin gallate from green tea, quercetin from fruits, and allicin from garlic.

This may be evidence of xenohormesisthe idea that plants respond to stress by producing chemicals that tell their cells to hunker down and survive.

In 2008, together with Konrad Howitz they penned the term xenohormesis Their theory is that animals evolved to sense certain chemicals in stressed plants as an early-warning system, of sorts. . Over the long-term, this provides humans with health and longevity. In the same way intermittent fasting and exercise are thought to. In fact, he says, they activate the same hormetic pathways.

Sinclair says we should be eating plants and foods raised under less-than-ideal conditions, organic, small farm-raised, or from our own backyard. When plants are stressed, they often add extra color to their stems or leaves.

For example, when a plant or a fruit is exposed to too much light, you may have noticed it produces extra red, blue or purple pigments. These are anthocyanins and they are produced not only by radiation damage, but drought, adverse temperatures, nutrient restriction, pathogens, and wounding. Xenohormetic molecules are typically produced alongside anthocyanidins. I look for leafy vegetables that are bright in color, not light green. I dont mind if they have holes eaten in them or are limp.

And if youre wondering which wine grapes have the highest resveratrol content? Sinclair says its pinot noir, because they are so stress-sensitive.

Sinclair suggests cold therapy is another way to better your lifespan chances. Cold therapy helps activate the mitochondria in your brown fat. He writes that his interest in the potential health benefits of cold therapy began in 2008 with a chance meeting at TEDMED with Ray Cronis former NASA scientist turned expert in nutrition and bioenergetics. The two began working together and they published a paper together with Andrew Bremmer at the NIH, titled The Metabolic Winter Hypothesis: A Cause of the Current Epidemics of Obesity and Cardiometabolic Disease.

Writes Sinclair: We propose that our 7-million-year evolutionary history, which was dominated by two seasonal challenges, lead to calorie scarcity and mild cold stress. But in the last 0.9 inches of our evolutionary mile, we solved them both. Put another way, we may be in evolutionary discordance between our biology that evolved to counter seasonal calorie scarcity and mild cold stress and our modern world of ubiquitous calories and excess warmth. Very few of us experience the outdoor cold of winter, and even fewer of us sleep at cool temperatures.

Yes, you guessed it. Sinclair takes a colder view of life. He leaves a window slightly open at night and avoids heavy blankets while he sleeps. He says he also turns the thermostat down to 67 at night. At the gym, he plunges into a cold pool up to his neck for at least 20 seconds. The scientist says doing this leaves him feeling refreshed and energized for the rest of the day. He expects his healthy brown fat to be turning even browner.

This is a controversial area for anyone in the scientific world to venture into. Perhaps more so for an academic specializing in aging. Realistically though, who wouldnt want to know what he is personally taking to age better? David Sinclair definitely looks a lot younger than his 51 years. According to multiple reports and broadcast material on the subject, he regularly tracks his biomarkers and takes vitamin D, vitamin K2, and aspirin.

Sinclair also uses three other longevity-specific substances each morning. These include resveratrol, NMN, and metformin, a diabetes drug currently being studied for its potential anti-aging effects. The researcher is always quick to point out to the media that hes not a medical doctor and that hes not recommending anyone do what he does. This is purely what he does personally, based on what he is learning.

While the natural human inclination is to seek the fountain of youth, theres never a shortage of naysayers. The stakes are particularly high in this area of health. David Sinclair may well be conducting his own real-time personal longevity experiment alongside his lab. However, whatever your viewpoint, I think we can all agree, the best advice is not to wait until the science is proven. You can already adopt many of these strategies without any risk. Be proactive about improving your lifespan now.

David A. Sinclair, Ph.D. A.O. is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He obtained his Ph.D. in Molecular Genetics from the University of New South Wales, Sydney in 1995. Dr. Sinclair is co-founder of several biotechnology companies (Sirtris, Ovascience, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others. He is also co-founder and co-chief editor of the journal Aging.

His work is featured in five books, two documentary movies, 60 Minutes, Morgan Freemans Through the Wormhole and other media. He is the inventor of 35 patents.

Sinclair and has received more than 25 awards and honors. These include the CSL Prize, The Australian Commonwealth Prize, Thompson Prize, Helen Hay Whitney Postdoctoral Award. As well as the Charles Hood Fellowship, Leukemia Society Fellowship, Ludwig Scholarship, Harvard-Armenise Fellowship, American Association for Aging Research Fellowship. Included are the Nathan Rodriguez Award from the National Institutes of Health, Ellison Medical Foundation Junior and Senior Scholar Awards. Merck Prize and the Genzyme Outstanding Achievement in Biomedical Science Award.

Sinclair was also awarded the Bio-Innovator Award, David Murdock-Dole Lectureship, Fisher Honorary Lectureship, Les Lazarus Lectureship and the Australian Medical Research Medal. His work has been recognized with The Frontiers in Aging and Regeneration Award, Top 100 Australian Innovators, and TIME magazines list of the 100 most influential people in the world.

David Sinclair is the author of the book Lifespan. A must-read for anyone interested in aging.

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Has Everything We've Been Taught About Aging Wrong? - Longevity LIVE

Randy Orton and Tommaso Ciampa got into a Twitter beef following NXT TakeOver: In Your House when Orton sent out a backhanded compliment about leg slaps.

Ciampa responded by saying he uses Orton matches to put his daughter to sleep and Orton noted that he seemed to upset one of the locker room leaders in NXT.

Speaking to CBS Sports, Orton clarified his "leg slap" comments and how he views NXT.

"So, the leg slap comment was just me having fun and it got taken a little too seriously," he noted before saying he's seen more leg slaps and repeated moves as so many wrestlers use a superkick or running knee.

"That has nothing to do with the state of Tommaso's physical wellbeing, but there's that style. If you're a talent and you've made it as far as NXT, which is very close to the top of the mountain ... if you think that you have to go out there and get powerbombed on the apron after neck surgery, or if you think you have to go out there and do these dives and flips bell to bell just because the fans want to see half a dozen near-death experiences? I feel sorry for you because you're not going to reap the benefits of what this business offers," said Orton. "One of those is longevity. I don't know anything about what NXT pay is like, but it certainly ain't Raw and SmackDown pay. I don't know what you get paid for a TakeOver, but I'm going to go out on a limb and guess that, at WrestleMania, my paycheck was bigger than the TakeOver guys. Now, I hate when guys talk about 'my big bank account' or 'my big check' or this or that and 'I'm more rich than you.' That's not what I'm saying here. I'm saying that NXT shouldn't be the goal. Raw or SmackDown should be the goal."

Orton went on to say that he wants Ciampa to have a long and healthy career where he can retire and not have to learn a new trade.

"I want to see all these guys succeed. When you're talking about that? Making money. It's a business. It's a business. You've got to make money. I would think, no matter how much you love NXT, you've got to look at the bigger picture. If you don't think you're going to last on the road for Raw and SmackDown? Do something about it. Go and sign a contract that calls for you to only show up at TV. They do NXT every week and they do a TakeOver whenever. They're wrestling about as much as we're wrestling, especially right now. With the future and no one knowing how many shows we're going to be putting on, I think it's a bit of a cop out to say, 'I can get four years of NXT versus one year of Raw or SmackDown,'" said Orton before noting that he would love to work with Ciampa and believes he's great at telling stories.

He continued, "All different kind of fans love all different kinds of styles and there's definitely a popular style down in NXT. I'm not saying fans are wrong and I'm not saying the wrestlers are wrong. I'm just saying there's no longevity in it. There's no chance you're going to be able to have a 10, 15, 20-year career and be able to support your family. If you have multiple kids, especially, there's no way to do that in NXT. That's why there's the major leagues and the major leagues are Raw and SmackDown. The major leagues are main eventing WrestleMania. Main eventing a TakeOver should be a huge notch on your belt. Winning the NXT championship should be a huge notch on your belt. But, I know when Kevin Owens won the NXT championship, he couldn't wait to get called up to the main roster because that dude is a bad motherf--ker and he can go. He wanted to show the world and he was going to reach more fans being on Raw, being on SmackDown, being in marquee matches in Madison Square Garden, being in WrestleMania on the Network. By doing that, he was going to be able to show how awesome of a talent he is."

Orton finished by saying NXT is one step away from the top and he doesn't want anyone to stop there.

As of now, Ciampa remains in NXT while Orton is one of the top stars on WWE Raw.

Continued here:
Randy Orton: Theres No Longevity In The NXT Style The Goal Should Be Raw Or SmackDown - Fightful

Saturday, June 13, 2020 4:00 AM

Dear Overseas Worker:To answer your second question first, n o, your benefit amounts will not change because you are married and both collecting. Based upon the numbers you provided, neither of you will be eligible for a spousal boost from the other because your benefit amounts at your FRA are too similar, so maximizing your individual benefits should be your goal.As for your other question, when you should start collecting depends upon a number of factors, including your financial needs and, importantly, your expected longevity. Both of you can get the maximum benefit available to you by waiting until you are 70 years old to claim, but that only makes sense if you are in good health and expect at least average longevity (about 84 for a man and 87 for a woman).If you claim benefits before you reach your full retirement age (66 for you and 66 plus 4 months for your husband), those benefits will be cut. If you collect now, your benefit would be cut by about 27% and your husbands by about 22% (based upon your respective years of birth). Further, if you claim before your full retirement ages and continue to work, youll be subject to Social Securitys earnings test, which limits the amount you can earn before they take back some of your benefits (the 2020 earnings limit is $18,240; if you exceed that theyll take back half of anything you earn over the limit). The earnings limit changes annually but goes away at your FRA.At your full retirement ages, youll be entitled to 100% of the benefits youve earned from your lifetime of working (approximately the amounts estimated now). If you can and do wait beyond your full retirement age (FRA), for each month you delay youll earn delayed retirement credits of 2/3 of 1% per month of delay (8% per year of delay), up to age 70 when your maximum benefit is reached. As a point of information, if you wait until your full retirement age to claim, you will have collected the same amount of money at age 78 as if you had claimed at age 62; and if you wait until age 70 to claim youll have collected the same amount of money at age 82 as if you had collected at your full retirement age. If you live at least until average longevity, youll collect more in cumulative Social Security benefits by waiting.So, when should you claim? If youre still working and earning professional salaries, then waiting at least until your full retirement age would be a wise choice. If you expect at least average longevity and dont need the money right away, waiting until age 70 would be a prudent strategy. But if you dont work and expect less than average longevity, then claiming at any time you need the money would be a reasonable decision. This is a choice only each of you can make.

By AMAC Certified Social Security Advisor Russell Gloor. This article is intended for information purposes only and does not represent legal or financial guidance. It presents the opinions and interpretations of the Association of Mature American Citizens Foundations staff, trained and accredited by the National Social Security Association.. NSSA and the AMAC Foundation and its staff are not affiliated with or endorsed by the Social Security Administration or any other governmental entity. To submit a question, visit our website (amacfoundation.org/programs/social-security-advisory) or email us atssadvisor@amacfoundation.org.

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In an industry flooded with content standing out from the crowd has arguably never been more crucial, but how is that achieved?Andy Sekula, head of games at Kalamba, believes that withmechanics and math originality you stand a fair chance of succeeding.

The theme and visuals of a slot game are what draws a player in, but its the mechanics that keeps them returning time and again. Innovations introduced in the last few years such as the Megaways engine have demonstrated how transformational a new feature can be for the whole gaming community particularly in an age of content overload where players are faced with myriad choice of games that barely differentiate.

For developers striving for originality, the race is now on between suppliers, both large and small, to create the next big feature that defines a new era. But that doesnt mean trying to reinvent the wheel every time.

Innovation in slot mechanics is a balancing act: introducing something that is too foreign can be off-putting to players, while leaning too heavily on proven successes means you fail at delivering something new.

The sweet spot lies in keeping with what is mostly familiar, improving on it, and introducing some novelty so that the gameplay feels fresh and exciting. And since its the games mechanics which define the math model and monetisation getting it right from the start can be the make or break of a games performance.

Fully understanding player preferences and behaviour is a fundamental component to the development of new features. It is important that studios make informed decisions based on objective evidence, rather than opinion keeping players top of mind from the early stages.

Creating that stickiness with players is an important part of ensuring a games success, longevity and profitability

When developers spend so much time with a game, it is easy to forget that players arecompletely new to it when released. A games creators therefore need to constantly consider how a player will interact with the slots features and mechanics, making sure they are easy to understand and, of course, add to the overall enjoyment.

Tracking engagement with previous releases provides a useful tool to gauge what works and what doesnt, offering a foundation of information on how features can be improved in future iterations.

At Kalamba, we look at the session lengths and number of rounds played to get an indication of the games instant performance, while the number of times a player returns determines whether the experience is appealing enough to come back to even after the games disappears from the lobby.

Creating that stickiness with players to which the mechanics are fundamental is an important part of ensuring a games success, longevity and profitability.

This performance data has been central to Kalambas design process and shaped thedirection of our portfolio in the last few years through feature enhancements. In the earlydays, we concentrated on high-volatility titles with complex mechanics that were targeted at slot enthusiasts.

While these performed well with the intended audience, with analysis of KPIs over time, combined with feedback from operators, we decided to switch tactics.

We now look at developing games with a lower base level but introducing customisable mechanics, such as our HyperBet feature, which allows players to increase the base bet amount of the game as well as the volatility, and HyperBonus, which provides a shortcut tothe bonus round.

It is only with new mechanics and math originality that new hits are created

By enabling players to adapt the gameplay to suit their preferred playstyle, weve broadened the appeal of portfolio, making our titles more accessible to casual players, whilst allowing those with more experience to increase the volatility to meet their risk appetite.

Using these innovations as a foundation for our game development, the Kalamba feature set has advanced dramatically, with new additions like LuckyLoops and progressive free spins moving the engagement dial even further.

The new LuckyLoops feature lets players accumulate special symbols on every base game spin and every tenth spin, the player is rewarded with a special spin, for example expanding accumulated symbols.

To complement our in-game concepts, we are also developing Bullseye, our promotional tools and social gaming inspired elements (think leaderboards and tournaments) that connect our portfolio.

In a content-flooded industry that is full of imitation and skins, it is only with new mechanics and math originality that new hits are created. And although not every feature iteration or new concept is going to be a winner, using data as a guide and of course, taking the occasional risk on an experiment you stand a fair chance of succeeding.

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Kalamba Games: Striving for mechanics that break the mould - Casino Beats

(Daniel Taylor - Kelowna Capital News)

Your morning start for Wednesday, June 17, 2020

Good morning, Okanagan! Happy hump day!

One study, conducted by a University of Sydney professor, titled Stairway to Hell: Life and Death in the Pop Music Industry, examined the deaths of artists which took place between 1950 and June 2014. The study specifically looked at longevity and the proportion of suicides, homicides, and accidental deaths. Longevity was determined by calculating the average age of death for each musician by sex and decade of their death. These averages were then compared with averages by sex and decade for the general U.S. population. The results? Musicians lifespans are 25 years shorter.

In Kelowna:

In Vernon:

In Penticton:

In Salmon Arm:

A South Okanagan massage therapist is no longer allowed to treat female patients after accusations he sexted during appointments and sneaked looks at patients naked bodies.

Last week, the College of Massage Therapists of British Columbia announced it launched an investigation into Brent Rowland, formerly of Naramatas now closed Equilibrium Massage Therapy.

A note posted to the Equilibrium Massage Therapy by Rowland, stated the practice is being suspended for the foreseeable future.

READ MORE: Central Okanagan teacher suspended for showing South Park, John Oliver to students

Daniel Taylor

Reporter, Kelowna Capital News

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Morning Start: Musicians have shorter life spans than the general population - Vernon Morning Star

Retirement can be joyous and less expensive if we take care of ourselves

In a recent survey of more than 5,000 workers, ranging from millennial to baby boomer, conducted by the Transamerica Center for Retirement Studies, eight in 10 participants asserted that they are in excellent or good health.

Those self-assessments seem optimistic when viewed aside national health data:

According to the Centers for Disease Control and Prevention, some 40% of adults are obese.

High blood pressure is an issue for more than four in 10 adult Hispanic and white Americans, and nearly six in 10 non-Hispanic black Americans.

An estimated one in four Americans at least 65 years old is diabetic, with 90%-plus of those cases being Type 2 diabetes that can be moderated, if not eliminated, through dietary changes.

Yes, there is a much longer list of illness and disease absolutely out of ones personal control. But weight, blood pressure and Type 2 diabetes are often conditions that can be managed or moderated through the personal initiative of a healthier diet and (more) exercising. Quality sleep is another lever that can improve health and quality of life, now and down the line.

A visit with your primary care physician, during which you dont minimize your health concerns but seek strong advice on addressing them, is a good start to feeling better. Dont leave the doctors office without a plan.

Additional motivation can come from the financial implications of being in poor health. Medical bills are a leading cause of bankruptcy in the U.S., and a relatively healthy retirement is a lot cheaper to fund than one burdened by heavy drug costs, doctor visits and hospitalizations.

The nonpartisan Employee Benefit Research Institute takes a deep data dive each year to estimate the out-of-pocket medical expenses 65-year-olds might encounter over the rest of their lives. The estimate accounts for Medicare premiums, deductibles and co-payments, and prescription drug costs not covered by Medicare supplemental plans. It explicitly does not include the cost of long-term care.

If a 65-year-old couple today wants a high probability (90%) that they will have the funds to pay for all those medical costs through the rest of their lives, they are estimated to need a combined $325,000 if they end up with high prescription drug costs (again, the 90th percentile). If their drug costs are at the median they would need $270,000.

Yes, both estimates are eye-openers, but remember, this is for two people, and it is for total expenses in retirement. Given increased longevity of retirees,

there is a 50 percent probability someone in average health at 65 will still be alive in their mid-80s. So that total cost is spread out over plenty of years. But even so, the difference between typical and high drug costs adds up to a big chunk of retirement funds. To understand longevitys impact on your retirement planning, read this:https://www.rate.com/research/news/retirement-expectancy

Taking better care of yourself is a key retirement-planning strategy. And its one of the rare times where doing something for your future self also provides a payoff in the here and now. A healthier approachbe it physical or mental (ideally both)is bound to help you feel better today.

Consider a couple hacks:

Share your goal with someone, an exercise or diet buddy, and make plans to check in together regularly. Sounds simple, but so often we keep this sort of stuff to ourselves. Yet having an accountability friend has been shown to help people stick to goals.

Write a letter to your 65- or 75-year-old self, sharing what you hope to be doing then. An academic research project found that people who went through this exercise were more likely to keep going to a gym.

Write it down. A record of exercise, eating, weight and blood pressure can help connect your daily activities to your longer-term goals.

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'Oh, I'm Fine' the Cost of Self-Deception About Health - Guaranteed Rate

Aunt Jemima, the long-standing brand that finally was put to rest this week, has slavery in its corporate DNA.

Nancy Green, who portrayed Aunt Jemima when the character was introduced at the Worlds Columbian Exposition in Chicago in 1893, was born into enslavement six decades earlier, on a plantation in Montgomery County, Ky.

By all accounts, Greens friendly personality made her a perfect corporate mascot, launching the Aunt Jemima name and commencing more than a century of dubious marketing. She was offered a lifetime contract to continue appearing as the character, the first of numerous Black women to play the part.

Aunt Jemima, along with Uncle Ben, who it was announced this week will also be getting the heave-ho, were not responsible for creating stereotypes. Bigotry isnt new.

But the indisputably racist brands, and their bewildering longevity, speak to the power of marketing in reinforcing offensive stereotypes.

Simply put, if corporate America hadnt given its full backing to creating and promoting these images as sales tools, making them both culturally legitimate and highly profitable, its debatable whether the countrys racial divisions would have run so deep for so long.

Theres very strong support for that premise, said Jerome Williams, a business professor at Rutgers University. Corporate America perpetuated this situation.

Judy Davis, a marketing professor at Eastern Michigan University, was even more emphatic.

Advertising and marketing play an important role in selling whiteness, she told me. They have played a role in perpetuating an image that whites are superior.

Williams related how, as a kid, his mom would serve Aunt Jemima pancakes or Uncle Bens rice, and the stereotypical branding never registered as overtly racist.

It was just part of the background noise, he said. I remember watching Amos and Andy on television and laughing along with the show.

In hindsight, he realizes how much cultural damage was being done.

They were very abhorrent images, Williams said. But like many African Americans, I just accepted this as the way the world was.

Thats now changing, hopefully forever, as America and other nations shine a harsh spotlight on racial mistreatment, inequality and insensitivity following the death of George Floyd and amid a resurgence of the Black Lives Matter movement.

Quaker Oats said Wednesday its retiring Aunt Jemima after more than 130 years of pitching the brand.

As we work to make progress toward racial equality through several initiatives, we also must take a hard look at our portfolio of brands and ensure they reflect our values and meet our consumers expectations, the Pepsi-owned company said in a statement.

Mars, owner of the Uncle Bens brand, quickly followed suit, declaring that the time has come to change the products brand identity.

Now is the right time to evolve the Uncle Bens brand, including its visual brand identity, which we will do, the company said. We dont yet know what the exact changes and timing will be, but we are evaluating all possibilities.

These are laudable moves. But its hard not to wonder if theyre less an an indication of corporate enlightenment and more an awareness that theres no longer money to be made perpetuating archaic and ugly stereotypes.

When it starts affecting corporate profits, thats when it starts having an impact, Williams said of criticism from consumers.

The Aunt Jemima brand has long reflected the values of a less-woke time. Case in point, a magazine ad from 1938 that depicted the white Jones family lamenting the sorry state of Moms pancakes.

And theres Aunt Jemima, in full Mammy regalia, standing in the window declaring, Dey sure needs me in dis house!

Marketing that way may not make people prejudiced. But it lends a corporate seal of approval to such thinking.

Branding is incredibly powerful. It can teach the world to sing and enjoy a bottle of Coke. And it can promote a smug sense of white superiority.

Once something is seen as normative, its typically not questioned and taken for granted, said Sonya Grier, a marketing professor at American University. Like fish in water. And this would allow such stereotypes to be perpetuated consciously or unconsciously in society.

Seeing Aunt Jemima on a box of pancake mix, she said, drives home the idea that a Black woman belongs in the kitchen as a servant or caretaker.

The lack of discussion, especially cross-race discussion of these issues traditionally, doesnt allow for the stereotypes to be challenged on a personal individual level, Grier said.

It goes even deeper than that.

While brands such as Aunt Jemima and Uncle Ben cant solely be blamed for systemic racism, by using these stereotypical icons to represent their brands they are giving credence to such stereotypes on a global platform, said Monique Bell, an associate professor of marketing at Fresno State.

Black people, and other underrepresented groups, already face implicit biases, and these representations only encourage prejudice and further dehumanization, she said.

Recently, its felt like every company under the sun has wanted to demonstrate its commitment to racial harmony and diversity.

Some of these declarations are undoubtedly sincere and aim to promote positive change. Others may be little more than me-too pandering.

Im a little skeptical, said Kevin Thomas, an assistant professor of multicultural branding and strategic communication at Marquette University. I believe its more of a calculation at this point on the part of marketers.

Well see.

If your company is committed to change, it cant just be about changing the symbolism, said Davis at Eastern Michigan University. Dropping certain names and imagery is a start, but theres a lot more companies can do.

It could take generations, in fact, for the influence of decades of racially questionable marketing to be undone.

Davis said that when she first heard the news about Aunt Jemima, she felt gratified. Then she made herself some pancakes.

They werent Aunt Jemima, but the connection was made.

Brands are mighty things. And they must not be tolerated when they do wrong.

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The Aunt Jemima and Uncle Ben brands marketed racism - Los Angeles Times

ONE Championship announced on Monday that theyre laying off 20% of their workforce.

The Singapore-based MMA promotion, which has been known for making very bold claims, unsurprisingly had their unique way of revealing the unfortunate news.

Their press release was mainly about claiming to add $70 million to its war chest from undisclosed existing and new investors, but they also mention a decision to have a 20% reduction of total worldwide headcount. The news was something their President was apparently thrilled to announce.

ONE Championship Adds US$70 Million To Its War ChestExisting And New Institutional Investors Participate

The largest global sports media property in Asian history, ONE Championship (ONE), today announced that it has added US$70 million to its war chest, bringing total capital to US$346 million. ONE Championship has also streamlined operations, including a 20% reduction of total worldwide headcount.

Hua Fung Teh, Group President of ONE Championship, stated: I am thrilled to announce that ONE Championship closed another round of funding a few weeks ago with existing institutional investors as well as a new institutional investor. I am full of gratitude for this strong vote of confidence amidst the worst global economic crisis in 100 years. With 9 figures of cash on the balance sheet and a streamlined organization, ONE Championship looks forward to continuing to delight our fans around the world with more heroes and new experiences for many years to come.

Apart from receiving flack from media and pundits on social media, the announcement also caught the attention of UFC President Dana White:

ONEs CEO Chatri Sityodtong also issued a separate memo to his employees that were being laid off. He spoke about a sad, heart-wrenching decision to let them go, noting how its necessary to ensure the companys longevity, while also boasting and claiming to have a strong balance sheet and a 9-digit war chest for the billion-dollar company.

Heres a snippet from the letter obtained by Tech in Asia:

The world is suffering from the single worst economic crisis in a hundred years due to Covid-19. After weeks of consultation with both our leadership team and our board of directors, I have made the decision to future-proof ONE Championship by both streamlining operations and sharpening core strategic priorities.

It is one of the most heart-wrenching decisions I have ever had to make in life. On the one hand, ONE has a strong balance sheet with a 9-digit war chest after todays new funding announcement. It puts us in the perfect position to continue aggressively building Asias largest global sports media property. On the other hand, these extraordinary times for the world require unusual prudence to protect our company and to ensure its longevity for many years to come. With the decision to sharpen our focus around core strategic priorities, ONE will undergo a 20% reduction in total worldwide headcount.

Josh Gross also spoke about the announcement, reporting that the layoffs go far beyond the 20% that ONE announced, with a figure closer to 50% - 60% of its workers, which includes all freelance contractors.

ONE spoke about COVID-19 and the economic crisis being the major reason for these layoffs. Like many companies, the MMA promotion has indeed been hit hard by the pandemic, and they havent hosted an event since February. That being said, their financial struggles date back years now.

As Bloody Elbow reported previously, documents that ONE themselves have filed with the Singapore government show massive losses that have increased each year. In 2018 alone, the company had losses of almost $59 million, with accumulated losses have amounted to a whopping $126 million.

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ONE Championship lays off sizable chunk of workforce to ensure its longevity - Bloody Elbow

KEY POINTS

Plant-based diet plans like the Mediterranean diet reduceheart disease risk by nearly 20%, according to recent research.

The experts at the Harvard T.H. Chan School of Public Health reported that people who followed the Mediterranean diet, Greek and Italian cuisine-based fight-and plant-based meals, or other plant-based diets had a 14-21% lower risk for cardiovascular diseases, depending on how well they adhered to it.

Higher compliance with a healthy eating plan was linked to a 10-20% reduced risk of heart diseases, according to the researchers.

We found that following a variety of healthy eating patterns confers significant health benefits in reducing the risk of cardiovascular disease," Dr. Frank B. Hu, the study author, professor, and chair of the Department of Nutrition at Harvard T.H. Chan School of Public School told UPI.

These heart-healthy diets share common characteristics such as higher consumption of fruits, vegetables, whole grains, legumes and nuts, and lower consumption of red and processed meats and added sugar," Hu told UPI.

The Study:

The researchers tracked the heart health of 165,794 women and 43,338 men for nearly 32 years. None of them had any history of heart disease. They evaluated the effects of four different dietary approaches on heart disease risk using several measures of adherence including the following:

Key Findings:

The researchers highlighted the fact that there is no magic bullet diet to health and longevity and that there is no such thing called a magic diet solution. They recommend consuming a variety of healthy foods in flexible ways and follow a healthy eating pattern according to each persons health needs, food preferences, as well as, cultural traditions.

mediterranean diet for longevity Photo: aytalina - Pixabay

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Higher Compliance With Mediterranean And Plant-Based Diets Reduce Heart Disease Risk Up To 21% - International Business Times

Dear Rusty: We served overseas for several years, not earning many quarters for Social Security. However, we have made sure that we paid in over time so we can receive a benefit, but it will not amount to much. For the past several years now, we have been back in the U.S., earning some professional salaries. Now it looks like at full retirement age my husband will get $1,147 per month, and I will get $1,026 per month. I was born in 1957 and my husband in 1956.

Question #1: For the most financial benefit, when should we each start collecting SS (either now or at full retirement age)? And question #2: Will our amounts change because we are married and both collecting? Signed: Overseas Worker

Dear Overseas Worker: To answer your second question first, no, your benefit amounts will not change because you are married and both collecting. Based upon the numbers you provided, neither of you will be eligible for a spousal boost from the other because your benefit amounts at your full retirement age (FRA) are too similar, so maximizing your individual benefits should be your goal.

As for your other question, when you should start collecting depends upon a number of factors, including your financial needs and, importantly, your expected longevity. Both of you can get the maximum benefit available to you by waiting until you are 70 years old to claim, but that only makes sense if you are in good health and expect at least average longevity (about 84 for a man and 87 for a woman).

If you claim benefits before you reach your full retirement age (66 for you and 66 plus 4 months for your husband), those benefits will be cut. If you collect now, your benefit would be cut by about 27% and your husbands by about 22% (based upon your respective years of birth). Further, if you claim before your full retirement ages and continue to work, youll be subject to Social Securitys earnings test, which limits the amount you can earn before they take back some of your benefits (the 2020 earnings limit is $18,240; if you exceed that theyll take back half of anything you earn over the limit). The earnings limit changes annually but goes away at your FRA.

At your full retirement ages, youll be entitled to 100% of the benefits youve earned from your lifetime of working (approximately the amounts estimated now). If you can and do wait beyond your FRA, for each month you delay youll earn delayed retirement credits of 2/3 of 1% per month of delay (8% per year of delay), up to age 70 when your maximum benefit is reached. As a point of information, if you wait until your full retirement age to claim, you will have collected the same amount of money at age 78 as if you had claimed at age 62; and if you wait until age 70 to claim youll have collected the same amount of money at age 82 as if you had collected at your full retirement age. If you live at least until average longevity, youll collect more in cumulative Social Security benefits by waiting.

So, when should you claim? If youre still working and earning professional salaries, then waiting at least until your full retirement age would be a wise choice. If you expect at least average longevity and dont need the money right away, waiting until age 70 would be a prudent strategy. But if you dont work and expect less than average longevity, then claiming at any time you need the money would be a reasonable decision. This is a choice only each of you can make.

Russell Gloor is an Association of Mature American Citizens certified social security advisor. To submit a question, visitamacfoundation.org/programs/social-security-advisory or email ssadvisor@amacfoundation.org

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Choose best time to claim benefits - GREAT BEND TRIBUNE - Great Bend Tribune

When it comes to dog food, we all want to make sure we are feeding our dogs all the goodness they need without any harmful ingredients or additives. I am one of those dog moms. Thats why I jumped at the opportunity to try Dr. Jeffs Optimum freeze-dried dog food and Daily Canine Care supplement. My dog was so excited after eating this food that she celebrated with some zoomies!

I adopted my female Hound Mix from Homeward Bound Animal Welfare Group in 2018. She is two years old and weighs 35 pounds. She currently has a healthy body shape, but I have to be careful about portion size with her. She is a bit on the short side and quickly becomes rotund if overfed. She currently eats a mix of a limited ingredient dry dog food topped with fresh fruit or veggies and homemade meals of meat or fish, whole grains, and veggies. Townes gets regular exercise on our daily 2-3 mile walks.

I grew up with a family dog and have had dogs of my own throughout my adulthood. Like many of us, I always fed my dogs a dry food that was convenient and affordable without giving much thought to ingredients or processing. That has changed. As I got older and became more aware of nutrition and its impact on my own health, I realized that I needed to have the same concerns for my dogs.

My dogs experienced health issues that I believe were directly tied to the food they ate. Terrible skin allergies plagued my adopted Black Lab Mix, Morgan. Then I lost my sidekick Murphy to cancer. I want Townes to live the longest, healthiest life possible. The food she eats plays an incredibly important role in that.

In a landmark five year study of over 500 dogs, researchers Bruno Sapy and Dr. Gerard Lippert concluded that a dogs diet is one of the most significant contributors to longevity. In fact, their research showed that dogs who eat homemade meals made from whole foods lived an average of 32 months longer than those who ate commercial dog food. That is almost three years! Dr. Jeffs Optimum and Daily Canine Care supplements are well-balanced, affordable, and nutritionally advanced. They offer you the convenience of kibble with the benefits of homemade, contributing to happiness, a lower risk of disease and obesity, and a longer life.

Dr. Jeff is a nationally renowned veterinarian and pet journalist. For over 35 years, he has been practicing veterinary medicine in Los Angeles. He is known as the Celebrity Vet for treating dogs whose humans have celebrity status. Dr. Jeff was drawn to veterinary medicine because of his love for animals. That love is the driving force behind Dr. Jeffs freeze-dried dog food and supplement. He and his team of dog lovers have developed a well-balanced, affordable, nutritionally advanced food, and probiotic supplement that helps dogs live longer, healthier, happier lives.

Freeze-drying is the most nutritionally sound way to preserve food. Freeze-dried foods are the same size and shape as the original food. They do not require refrigeration and are shelf-stable for long periods of time. When you place freeze-dried foods in water, they reconstitute, returning to their original form. According to industry leader Freeze-Dry Foods, freeze-dried foods maintain nutrients, color, flavor, and texture often indistinguishable from the original product. Dr. Jeffs freeze-dried dog food allows you to serve your dog the nutritional equivalent of homemade fresh foods without the fuss.

The ingredients in Dr. Jeffs Optimum are simple, limited, and real. Beef, turkey, and duck are the first ingredients in this 32% protein food for dogs. Optimum also includes two different types of organ meat and two different types of seafood. Actual fruit and vegetables and specially selected additives like turmeric, folic acid, and kelp make this formula uniquely designed for health and wellness. The ingredients are not just wholesome; they are evolutionary.

Optimum was designed by experts who understand what a dog should be eating. Dog moms and dads can feel secure knowing their dog will get all the energy-lifting and disease-fighting ingredients they need with Optimum. They can also feel confident that Optimum is free of artificial flavors, colors, synthetic preservatives, and biologically unsound fillers like corn, soy, and wheat.

When changing to Optimum, you should phase it in over the course of a week. This is done to avoid digestive upset for your dog. A handy schedule is included in the package that Dr. Jeffs ships for free. When I opened the package, my dog recognized right away that something special was about to be served up. I added water per the instructions and watched as the nuggets rehydrated and released a dog-pleasing aroma of meat.

I could barely get the bowl down before she gobbled it up and licked the bowl. Afterward, she was positively bursting with energy and showed me how happy she was with an athletic zoom around the yard. I like to mix things up for her at meals, offering her a variety of tastes and textures. One of the things that I like best about Dr. Jeffs Optimum is that it can be used as the primary meal or as a topper to change things up.

One of the easiest ways to support well being is through probiotic supplementation. This is true for humans and dogs! Probiotics support healthy digestion, nutrient absorption, and the bodys immune system. Dr. Jeffs Canine Care gives your dogs an unprecedented ten different strains of probiotics along with three super ingredients.

When I first used Dr. Jeffs Canine Care, Townes nose let her know that something delicious was being sprinkled on her food. This supplement is infused with bacon flavor, and we all know that dogs dig bacon. It was helpful to mix in into the other food with a bit of water, which spread the pleasant taste over the entire dish and ensured that she would ingest all of the dissolved powder.

I look forward to seeing how this supplement will help her maintain a healthy weight and body shape. She also has pretty severe anxiety in the car. Research has pointed to a reduction in anxious behaviors in canines through probiotic supplementation. Using this potent 10-strain formula may be just the supplement she needs to feel calm and relaxed on necessary car rides.

The dog lovers at Dr. Jeffs are so confident that you will love their food for dogs that they always offer an unconditional 60-day money-back guarantee. If you or your dog are not over the moon with the results you get from Optimum, they will gladly refund every cent of your order, without questions. However, there is something even better being offered to the iHeartDogs community. For a limited time, you can get a bag of Optimum for free! Dont wait. Try Dr. Jeffs Optimum today!

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Freeze Dried Dog Food for Health and Longevity - iHeartDogs.com

Global reinsurance broker Aon says longevity markets are continuing to function effectively despite COVID-19 and has cautioned pension schemes against over-reacting to high short-term UK mortality data when setting their long-term mortality assumptions.

Tim Gordon, partner and head of Demographic Horizons in Aons Risk Settlement Group, noted how were emerging from the initial wave of the global COVID-19 pandemic with no effective vaccine and with some critical aspects still unknown. As a result, some people assume that life expectancy must have reduced, but this is not necessarily the case.

While there are potential outcomes of this crisis that could reduce life expectancy, including the possible impact of economic recession, there are also potential outcomes that could result in higher life expectancy, said Gordon.

These could include increased spending on health and social care, and a potential hardening of the UK to future pandemics.

On top of this, the socio-economic profile of pension schemes means that their liabilities are typically partially insulated from the variations we see in national mortality statistics.

Accordingly, it would be premature now to make major changes to best estimate longevity assumptions in either direction. Indeed, it is reasonable for median best estimate assumptions to remain broadly unchanged.

Martin Bird, senior partner and head of Aons Risk Settlement Group, added, Longevity markets have continued to function efficiently over the course of the crisis to date, with bulk annuities and longevity swap transactions continuing apace.

Trustees and sponsors have, in our experience, taken the view that risk settlement forms part of their long-term risk management strategy and have been comfortable with proceeding with transactions, despite the turbulence from COVID-19.

In fact, in some cases, agile clients have been able to take advantage of pricing opportunities, such as those arising from increased credit spreads earlier in the crisis.

More than ever, it is important for schemes to keep their wits about them when entering a potential transaction.

Particular features in the current environment are the need to understand the consequences of different on-risk dates and the potential for regret risk as well as ensuring that investment portfolios are adequately stress-tested to guard against any later liquidity problems.

Read more:
Aon warns against over-reaction to short-term COVID-19 mortality data - Reinsurance News

JPMorgans strategists have reportedly found bitcoins market structure to be more resilient than those of currencies, equities, Treasuries, and gold. In a new report on bitcoins stress test, JPMorgan wrote that cryptocurrencies have longevity as an asset class.

In a new report entitled Cryptocurrency takes its first stress test: Digital gold, pyrite, or something in between? JPMorgans strategists say bitcoin is looking mostly positive, Bloomberg reported Friday. The report, led by head of U.S. interest rate derivatives strategy Joshua Younger and cross-asset research analyst Nikolaos Panigirtzoglou, shows that cryptocurrencies have longevity as an asset class.

The report examines bitcoin, cryptocurrencies, and other financial assets as they plunged in March when the coronavirus pandemic exploded in the U.S., causing shutdowns that crippled the economy. While bitcoin crashed to under $4,000, it bounced back faster than most other assets and recouped most of its value by the end of April. Moreover, bitcoins valuations did not diverge much from intrinsic levels during the March panic. Though the bubble collapsed as dramatically as it inflated, the strategists wrote:

Bitcoin has rarely traded below the cost of production, including the very disorderly conditions that prevailed in March.

The JPMorgan strategists also found that the cryptocurrencys price action points to their continued use more as a vehicle for speculation than medium of exchange or store of value, noting that bitcoin appears to have been correlated to riskier assets like equities.

Furthermore, the report describes that there were few signs of a flight to liquidity within the asset class, as most cryptocurrencies collectively fell in March. Concluding that bitcoin weathered its stress test well, the strategists wrote: there is little evidence of run dynamics, or even material quality tiering among cryptocurrencies, even during the throws of the crisis in March.

The report also explores liquidity, or the bid-offer spread of the order book, which is directly related to volatility. When the order book thins, a given transaction could result in a larger price change, and vice versa, the news outlet conveyed. Though bitcoin saw among the most severe drops in liquidity around the peak of the crisis, that disruption unwound itself much faster than other asset classes. According to the publication, the strategists wrote:

The coins market structure turned out to be more resilient than those of currencies, equities, Treasuries and gold.

JPMorgan has come a long way in its recognition of bitcoin. In September 2017, CEO Jamie Dimon called bitcoin a fraud, only to regret saying it a few months later. Now JPMorgan Chase is even providing banking services to bitcoin exchanges: Coinbase and Gemini. Last month, the company agreed to pay $2.5 million to settle a class-action lawsuit for overcharging fees for crypto transactions.

What do you think about JPMorgan changing its views on bitcoin? Let us know in the comments section below.

Image Credits: Shutterstock, Pixabay, Wiki Commons

Disclaimer: This article is for informational purposes only. It is not a direct offer or solicitation of an offer to buy or sell, or a recommendation or endorsement of any products, services, or companies. Bitcoin.com does not provide investment, tax, legal, or accounting advice. Neither the company nor the author is responsible, directly or indirectly, for any damage or loss caused or alleged to be caused by or in connection with the use of or reliance on any content, goods or services mentioned in this article.

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JPMorgan: Bitcoin's Market Structure More Resilient Than Currencies, Equities, Treasuries and Gold | News - Bitcoin News

SALT LAKE CITY In April, a Virginia pastor died from the coronavirus after telling his congregation to ignore physical distancing rules. Even after the story made national news, some religious leaders continued to defy public health orders and hold services, including a Louisiana pastor who told his church members, God gave you an immune system to kill that virus.

The next month, the Centers for Disease Control and Prevention warned the virus can spread easily at large religious gatherings, citing a case where two people with COVID-19 infected 35 others in March at church events in Arkansas.

Stories like these show the potential danger of holding large meetings while the coronavirus continues to claim U.S. lives and could cast religious leaders who insist on public worship in a negative light. But Harold G. Koenig, professor of psychiatry and director of the Center for Spirituality, Theology and Health at Duke University Medical Center, has some positive news for people of faith. He argues that religiousness may actually reduce a persons risk of contracting and dying from COVID-19.

According to Koenig, people who participate in organized religion or have their own spiritual practices are less likely to engage in unhealthy behaviors like smoking and drinking and more likely to have good habits like eating well and exercising. Not only can religious and spiritual involvement impact peoples physical health via their lifestyle choices, but it can also have a significant effect on their emotional well-being, said Koenig. All these factors combined can give a persons immune system a leg-up in fighting off viruses of any kind, he said.

Theres no question religion has an impact on both susceptibility to viral infections and recovery from it once youre infected, said Koenig, who was raised Catholic and now practices in a Protestant church. This just makes sense when you think about it.

However, Nicole Fisher, president of Health & Human Rights Strategies, a health care and human rights-focused advising firm in Washington, D.C., warns that religion and spirituality are not protective measures against COVID-19 on their own.

Viruses dont have any respect for religion, race, gender, politics or anything else. They look for a suitable host, and that can be anyone not taking proper precautions, said Fisher, who is spiritual but does not associate with a particular religion.

Still, there are clear links between beliefs, emotions and the body, Fisher said.

Prayer alone cannot cure you, Fisher said. But, with medical attention appropriate for how bad your illness is, prayer, meditation and faith can certainly bring a person peace of mind which can undoubtedly improve mental and emotional health, which is oftentimes linked to physical health.

More than a hundred studies have found that religious people are less likely to smoke, a habit which has a large impact on coronavirus outcomes.

According to Stanton Glantz, a professor of medicine and director of the University of California, San Franciscos Center for Tobacco Control Research and Education, research shows smoking nearly doubles a persons risk of COVID-19 disease progression, which could involve the need for critical care or death.

Glantz explained that the respiratory system has a very strong natural immune function, starting with microscopic hairs called cilia in the nose that trap viruses, bacteria and toxins. Deeper inside the lungs, cells called macrophages gobble up those things that can harm the body.

Smoking disables a lot of that immune function and makes you more susceptible to getting infected. Then if you get infected, the infections are worse, said Glantz, who added that vaping has a lot of the same effects as smoking.

According to Koenig, most research involving religion and health looks at Christianity, which promotes healthy behaviors by teaching that the body is a temple. But there are a number of studies that also examine Islam, Judaism, Buddhism and Hinduism, which all espouse similar beliefs about the sanctity of the body. Vegetarianism and yoga practices associated with Hinduism and mindfulness and breathing practices associated with Buddhism can also have direct health benefits, Koenig said.

A 2017 study by researchers from the Emory Rollins School of Public Health categorized subjects as Protestant, Catholic, Jewish, other religion or no religion. The study demonstrated a link between regular attendance at religious services with improved health and lowered mortality. They found that people who attended services frequently had a 40% lower hazard of mortality compared with those who never attended. Even those who attended services less frequently had a greater protection against mortality than those who didnt attend at all, but there were no differences by religious affiliation.

Stress increases susceptibility to viral infections, said Koenig, but individual spiritual practices and the support networks that come with organized religion can promote emotional well-being.

A big part of going to church is the social support in the community that one receives, said Carolyn Aldwin, director of the Center for Healthy Aging Research at Oregon State University. Social integration has a big effect on health outcomes.

Aldwin was raised Catholic and now attends an Episcopal church. To protect against the coronavirus, religious communities can support people who are older or immunocompromised by calling and checking in on them, or providing services like grocery shopping so they can avoid going out, Aldwin said.

The benefits of emotional self-regulation are also significant, said Aldwin, who has studied the effects of religion and spirituality on people with congestive heart failure.

When you have something like congestive heart failure, which is very hard to regulate and difficult to live with, being calmer and happier, and maybe feeling supported may allow you to experience less distress and even live longer, Aldwin said.

According to Koenig, positive emotions have the opposite effect on the immune system that negative emotions and stress have.

If you have meaning and purpose, if you have joy and satisfaction with life, if you experience a sense of peace, all of that has a positive impact on the immune system in the exact opposite way seen with chronic stress, anxiety and depression, Koenig said.

Cardiologist Dhanunjaya Lakkireddy, medical director of the Kansas City Heart Rhythm Institute, has set out to test the health impacts of one particular spiritual practice: prayer.

Lakkireddys COVID prayer study is set up as a double-blind randomized control trial, where coronavirus patients who voluntarily enroll on the website will be assigned into either a control group, or a group that will be prayed for by various volunteer religious groups representing the Christian, Muslim, Hindu, Jewish and Buddhist traditions. Lakkireddy and his colleagues plan to measure whether this remote intercessory prayer affects coronavirus outcomes like mortality, number of days in the ICU and days on a ventilator.

Lakkireddy was born into Hinduism and went to a Catholic school, but doesnt consider himself to belong to one religion in particular. He said the study required hardly any funding from the institute because he and others have all volunteered their time.

I was always intrigued by this idea of a supernatural divine power that can impact what we do as human beings on this earth, said Lakkireddy. As scientific and critical as I want to be in my thinking, the question about this divine force interested me.

But Aldwin is skeptical that any one aspect of spirituality, like prayer will prove to have a large impact on health with the coronavirus.

People who are sincerely religious have multiple things going for them, its the community which provides support, almost like a social safety net. Theres the better health behaviors, the calmness and acceptance in the face of adversity, said Aldwin. Its the whole package.

While some religious practices and belief systems may be correlated with healthy behaviors, the benefits could be instantly negated if people of faith are gathering to worship in large groups without the proper precautions, like social distancing and wearing masks. Multiple coronavirus outbreaks have been traced to religious groups, like Orthodox Jewish communities in New York or the Shincheonji religion in South Korea.

Religiousness, spirituality or faith, as in all facets of life and current health challenges, can be part of the problem or part of the solution, said Jeff Levin, University Professor of epidemiology and population health and director of the program on religion and population health at Baylor University. Where there are messages coming from the pulpit, or coming from religious leaders, telling people to ignore public health messages, I just think its incredibly foolish.

With coronavirus fatalities decreasing by the week across the country, U.S. churches are beginning to open back up. But most are trying to discourage the hugging and hand-shaking that typically accompanies fellowshipping. Some are implementing rules regarding how close people can sit in the pews, or eliminating the tradition of singing hymns because exhaling air with increased force can spread the virus farther.

Levin, who is Jewish, said he thinks these precautions are reasonable and wise.

Churches and pastors and religious organizations shouldnt be a source of anxiety for people, or discouragement, they should be supporting people and letting people know we will get through this, just a little longer, said Levin. We dont want to undo the good that weve done. There is still so much we dont know about the virus, and we are still learning that things could go south at any moment. Its not time for a victory lap at all.

See more here:
COVID-19 and the link between religious practices and personal health - Deseret News

Yesterday, in the wake of reports that AMD motherboard vendors have applied BIOS firmware to purposely misreport key power telemetry, AMD issued a statement to Tom's Hardware. It said that it has seen these reports, and that it is going to investigate further. The main worry is that while motherboard vendors have made these changes to squeeze the best performance from AMD silicon, a side effect could possibly be felt in processor stability or longevity.

Winding back a little, this story emanated from a hardware analysis and reporting feature introduced by the developers of HWinfo recently. The feature is dubbed Power Reporting Deviation, and in the words of the authors it "tells how much the CPU telemetry seen by the CPU differs from real world (expected) data". Furthermore, HWinfo fields an accusation against vendors, saying the deviation "is usually caused by mainboard vendor (often intentionally) providing wrong calibration data in BIOS (AGESA) to fool the CPU to run at a higher power than the limit for the SKU".

Of course the motherboard market is very competitive, better performance sells, and the manufacturers appear to be indulging in one-upmanship, by hook or by crook. In effect these motherboard vendors are secretly overclocking your AMD processor, by fiddling the data sent to AMD's Adaptive Voltage and Frequency Scaling (AVFS) algorithms.

HWinfo devs observed the above CPU power reporting deviation on a Ryzen 9 3900X running Cinebench

AMD's response is to the above revelations at this time is to soothe user-concerns. It says that while it is looking into the accuracy of the reports, AMD processors contain an array of safeguards which should still maintain CPU safety and longevity. For clarity the full statement is below:

Going forward it will be interesting to see if further investigations by AMD finds that these motherboard firmware misreporting tweaks are indeed damaging, and whether its board partners will continue to implement them now this info is in the open. Lastly, change will depend on whether AMD puts pressure on board partners to alter their behaviour.

See original here:
AMD responds to motherboards misreporting power telemetry - Mainboard - News - HEXUS

A person is seen walking in the streets of Akita in this file photo. (Mainichi/Kaho Shimokobe)

AKITA -- Getting a good night's sleep is essential to leading a healthy life, and in Japan it's the people of the northern prefecture of Akita who are getting the most pillow time, and the only people in the entire country to manage over eight hours in bed per day on average. The Mainichi Shimbun sat down with a sleep expert to find out their secrets.

According to the results of the Internal Affairs and Communications Ministry Statistics Bureau's 2016 "social and lifestyle basic research," average sleep time in Japan stood at seven hours and 40 minutes, while that of Akita Prefecture residents was eight hours and two minutes. Compared to those living in Saitama Prefecture, north of Tokyo, who got the least sleep at an average of seven hours and 31 minutes, Akitans snoozed at least half an hour longer.

Former Japanese Society of Sleep Research chairman and current Akita Prefectural Mental Health and Welfare Center director Tetsuo Shimizu explains that the possible main cause of longer sleep hours is that senior citizens make up a large part of Akita Prefecture's population. The Cabinet Office's 2019 Annual Report on the Aging Society says 36.4% of the prefecture's population was aged 65 and up in 2018, making it the only prefecture with a percentage higher than 35. Shimizu says one can argue that the more retired people there are, the more people there are with the time to have a proper sleep.

Shimizu also noted other rankings that appear in the Statistics Bureau's research, such as that for commuting times. Akita Prefecture placed 43rd, tied with three other prefectures including Aomori, for the second shortest time. The prefectures with the three longest commuting times -- Kanagawa, Chiba and Saitama, all bordering Tokyo -- are also the prefectures with the shortest sleep hours.

"Akita Prefecture is so far away from a major metropolitan area and it is also a major farming prefecture. Many residents probably spend only limited time on commuting," says Shimizu.

Furthermore, Shimizu points to the average bedtime of the Akitans as a factor contributing to their country-topping shuteye stats. According to one of the charts in the lifestyle research, Akita Prefecture residents go to bed at 10:33 p.m. on average, earliest in the country. The early bedtime is evidence that there are many older residents with moved-up sleep-wake cycles, and Shimizu comments, "We don't have many daylight hours in winter here and it gets freezing cold, so people would be more likely to say, 'Let's not waste money for kerosene and get in bed already.'"

Longer sleeping hours would seem to promise health benefits for Akitans. But according to the Health, Labor and Welfare Ministry's 2015 longevity list broken down by prefecture, Akita is second-last for men, at 79.51 years, and fourth from the bottom for women at 86.38 years.

Shimizu comments, "Akitans like drinking, so I suspect there are many of them who drink a lot before going to bed and just pass out. That might be negatively affecting the benefits of sleep." Backing Shimizu's claim, Statistics Bureau research on household spending in prefectural capitals and government-designated major cities showed that people in the city of Akita spent the most money on alcohol per year, averaging 55,920 yen (about $510) in 2017 through 2019, highlighting Akitans' love of drinking.

(Japanese original by Hiroshi Takano, Akita Bureau)

More:
Not so sleepless in Akita: The secrets of the Japanese prefecture getting the most Zs - The - The Mainichi

After their meteoric rise in the 80s, Bon Jovi spent most of the next decade weathering the trends and outlasting the tag of being a hair-metal band. After the hard-rockin hedonism of Slippery When Wet and New Jersey , both 90s albums (Keep the Faith and These Days) were about getting serious. There were more epics, more stories and a lot less fist-waving. Both had darker lyrics than usual, and Keep the Faith included Dry County, their first and only ten-minute track. The results were critical praise but a lower commercial profile. For the first time, the Jersey lads were in danger of a long-term career built on playing their old hits.

But Crush changed all that, rebooting the band when it arrived in June 2000. The album opens with a trio of hit singles, but there isnt a song here that wouldnt jump right out of the radio. Its really the first Bon Jovi album that doesnt aim for a unified sound, giving each track a feel of its own. They do sleek and modern, they do guitar-slinging retro, post-grunge and pure pop, depending on what a song calls for. There are also a few hints of the Americana direction theyd head in over the next decade.

Listen to Crush on Apple Music and Spotify.

Much of Crushs success can be credited to an infusion of new blood. Bassist Hugh McDonald was now settled in the band, having replaced Alec John Such in Bon Jovis first-ever personnel change a move that initially shocked fans who thought the five-way partnership was unshakeable. Another key player who took a backseat this time around was songwriter Desmond Child, who added the hit sheen to You Give Love a Bad Name and Livin On A Prayer. Jon Bon Jovi and Richie Sambora did the lions share of writing on Crush and the main co-writer was Billy Falcon, an upstart whose only previous major credit was co-writing (with Bon Jovi) Sometimes Its a B__ch for Stevie Nicks.

Most surprisingly, theres no big-name producer involved with Crush. Hitmaker Bruce Fairbairn was set to produce before his sudden heart attack, followed by Metallica man Bob Rock who was also considered. Finally, Bon Jovi and Sambora decided to co-produce with Luke Ebbins a young guy with plenty of ideas and zero hits to his credit. The gamble paid off, and Crush came out sounding polished but fresh, with no obvious fingerprints on it.

While theres more to Crush than its hit singles, lets dive right into the hit singles. For most bands, Its My Life is the kind of song that comes along once in a career an undeniable anthem, with a universal message and an unshakeable hook. From the two pounded chords that open, it has the sparkle of a pop hit, but its also steeped in classic rock. During promotions for the album, Jon Bon Jovi freely admitted he pinched the songs title and attitude from the Animals. The lyric also namechecks Sinatra and checks in with Tommy and Gina from Livin On a Prayer turns out theyre doing fine and Sambora caps it all off with a talkbox solo, likely the last one to appear on a hit single.

The second single, Say It Isnt So, pulls off the neat trick of sounding like Humble Pie in the verses and The Beatles in the choruses, while Thank You for Loving Me is the albums obligatory ballad, this time done with real strings (and a nice Sambora riff at the very end).

Sambora does some of his best work between the lines, including a few big moments on Next 100 Years, which is a three-minute song with a four-minute coda. It starts as a catchy love song, then pulls a chanted Hey Jude-type fade before the band revs up and Sambora cuts loose. Its a live-sounding moment and tops the list of singles that should have been.

In the period leading up to the 90s and then post-9/11, Bon Jovi got political, but Crush marked the bands return to pure, uncomplicated fun. Long-haul fans doubtlessly appreciated Just Older, a rousing tune that argued hitting middle age was no big deal. And anyone who remembered the 70s had to appreciate Captain Crash & the Beauty Queen from Mars, the only Bon Jovi song that clearly nods to the glitter era. (Even the title sounds like a lost Mott the Hoople track). The finale, One Wild Night, is such a fist-waver that it became the title of a live album a year later.

But the buried treasure on Crush is I Got the Girl, tucked away toward the end. Musically it encapsulates the album, starting as moody electronic pop and then chord-slinging in the chorus. Lyrically it appears to be one more Bon Jovi song about lucking out and finding the perfect partner, until he comes up with the easy-to-miss line the Queen of Hearts will always be a five-year-old princess to me. Yes, hes singing about his daughter, pulling the same narrative trick Chuck Berry did on Memphis. Its the kind of moment that keeps Bon Jovi honest, and a little endearing: Behind all that streamlined pop and arena fireworks sits a beaming dad.

Crush can be bought here.

Listen to the best of Bon Jovi on Apple Music and Spotify.

Read the original here:
Crush: How Stadium Heroes Bon Jovi Reclaimed The Rock Scene - uDiscover Music

Longevity and Anti-senescence TherapyMarket 2020: Inclusive Insight

Los Angeles, United States, May 2020:The report titled Global Longevity and Anti-senescence Therapy Market is one of the most comprehensive and important additions to Alexareports archive of market research studies. It offers detailed research and analysis of key aspects of the global Longevity and Anti-senescence Therapy market. The market analysts authoring this report have provided in-depth information on leading growth drivers, restraints, challenges, trends, and opportunities to offer a complete analysis of the global Longevity and Anti-senescence Therapy market. Market participants can use the analysis on market dynamics to plan effective growth strategies and prepare for future challenges beforehand. Each trend of the global Longevity and Anti-senescence Therapy market is carefully analyzed and researched about by the market analysts.

Longevity and Anti-senescence Therapy Market competition by top manufacturers/ Key player Profiled: CohBar, TA Sciences, Unity Biotechnology, AgeX TherapeuticsInc, PowerVision Inc.

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Global Longevity and Anti-senescence Therapy Market is estimated to reach xxx million USD in 2020 and projected to grow at the CAGR of xx% during 2020-2026. According to the latest report added to the online repository of Alexareports the Longevity and Anti-senescence Therapy market has witnessed an unprecedented growth till 2020. The extrapolated future growth is expected to continue at higher rates by 2026.

Longevity and Anti-senescence Therapy Market Segment by Type covers: Hemolytic Drug Therapy, Gene Therapy, Immunotherapy, Other Stem Cell Therapies

Longevity and Anti-senescence Therapy Market Segment by Application covers:Hospital, Medical Service Institution, Drug and Device Sales

After reading the Longevity and Anti-senescence Therapy market report, readers get insight into:

*Major drivers and restraining factors, opportunities and challenges, and the competitive landscape*New, promising avenues in key regions*New revenue streams for all players in emerging markets*Focus and changing role of various regulatory agencies in bolstering new opportunities in various regions*Demand and uptake patterns in key industries of the Longevity and Anti-senescence Therapy market*New research and development projects in new technologies in key regional markets*Changing revenue share and size of key product segments during the forecast period*Technologies and business models with disruptive potential

Based on region, the globalLongevity and Anti-senescence Therapy market has been segmented into Americas (North America ((the U.S. and Canada),) and Latin Americas), Europe (Western Europe (Germany, France, Italy, Spain, UK and Rest of Europe) and Eastern Europe), Asia Pacific (Japan, India, China, Australia & South Korea, and Rest of Asia Pacific), and Middle East & Africa (Saudi Arabia, UAE, Kuwait, Qatar, South Africa, and Rest of Middle East & Africa).

Key questions answered in the report:

What will the market growth rate of Longevity and Anti-senescence Therapy market?What are the key factors driving the global Longevity and Anti-senescence Therapy market size?Who are the key manufacturers in Longevity and Anti-senescence Therapy market space?What are the market opportunities, market risk and market overview of the Longevity and Anti-senescence Therapy market?What are sales, revenue, and price analysis of top manufacturers of Longevity and Anti-senescence Therapy market?Who are the distributors, traders, and dealers of Longevity and Anti-senescence Therapy market?What are the Longevity and Anti-senescence Therapy market opportunities and threats faced by the vendors in the global Longevity and Anti-senescence Therapy industries?What are sales, revenue, and price analysis by types and applications of Longevity and Anti-senescence Therapy market?What are sales, revenue, and price analysis by regions of Longevity and Anti-senescence Therapy industries?

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Table of ContentsSection 1 Longevity and Anti-senescence Therapy Product DefinitionSection 2 Global Longevity and Anti-senescence Therapy Market Manufacturer Share and Market Overview2.1 Global Manufacturer Longevity and Anti-senescence Therapy Shipments2.2 Global Manufacturer Longevity and Anti-senescence Therapy Business Revenue2.3 Global Longevity and Anti-senescence Therapy Market Overview2.4 COVID-19 Impact on Longevity and Anti-senescence Therapy IndustrySection 3 Manufacturer Longevity and Anti-senescence Therapy Business Introduction3.1 CohBar Longevity and Anti-senescence Therapy Business Introduction3.1.1 CohBar Longevity and Anti-senescence Therapy Shipments, Price, Revenue and Gross profit 2014-20193.1.2 CohBar Longevity and Anti-senescence Therapy Business Distribution by Region3.1.3 CohBar Interview Record3.1.4 CohBar Longevity and Anti-senescence Therapy Business Profile3.1.5 CohBar Longevity and Anti-senescence Therapy Product Specification3.2 TA Sciences Longevity and Anti-senescence Therapy Business Introduction3.2.1 TA Sciences Longevity and Anti-senescence Therapy Shipments, Price, Revenue and Gross profit 2014-20193.2.2 TA Sciences Longevity and Anti-senescence Therapy Business Distribution by Region3.2.3 Interview Record3.2.4 TA Sciences Longevity and Anti-senescence Therapy Business Overview3.2.5 TA Sciences Longevity and Anti-senescence Therapy Product Specification3.3 Unity Biotechnology Longevity and Anti-senescence Therapy Business Introduction3.3.1 Unity Biotechnology Longevity and Anti-senescence Therapy Shipments, Price, Revenue and Gross profit 2014-20193.3.2 Unity Biotechnology Longevity and Anti-senescence Therapy Business Distribution by Region3.3.3 Interview Record3.3.4 Unity Biotechnology Longevity and Anti-senescence Therapy Business Overview3.3.5 Unity Biotechnology Longevity and Anti-senescence Therapy Product Specification3.4 AgeX TherapeuticsInc Longevity and Anti-senescence Therapy Business Introduction3.5 PowerVision Inc. Longevity and Anti-senescence Therapy Business IntroductionSection 4 Global Longevity and Anti-senescence Therapy Market Segmentation (Region Level)4.1 North America Country4.1.1 United States Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.1.2 Canada Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.2 South America Country4.2.1 South America Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.3 Asia Country4.3.1 China Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.3.2 Japan Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.3.3 India Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.3.4 Korea Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.4 Europe Country4.4.1 Germany Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.4.2 UK Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.4.3 France Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.4.4 Italy Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.4.5 Europe Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.5 Other Country and Region4.5.1 Middle East Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.5.2 Africa Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.5.3 GCC Longevity and Anti-senescence Therapy Market Size and Price Analysis 2014-20194.6 Global Longevity and Anti-senescence Therapy Market Segmentation (Region Level) Analysis 2014-20194.7 Global Longevity and Anti-senescence Therapy Market Segmentation (Region Level) AnalysisSection 5 Global Longevity and Anti-senescence Therapy Market Segmentation (Product Type Level)5.1 Global Longevity and Anti-senescence Therapy Market Segmentation (Product Type Level) Market Size 2014-20195.2 Different Longevity and Anti-senescence Therapy Product Type Price 2014-20195.3 Global Longevity and Anti-senescence Therapy Market Segmentation (Product Type Level) AnalysisSection 6 Global Longevity and Anti-senescence Therapy Market Segmentation (Industry Level)6.1 Global Longevity and Anti-senescence Therapy Market Segmentation (Industry Level) Market Size 2014-20196.2 Different Industry Price 2014-20196.3 Global Longevity and Anti-senescence Therapy Market Segmentation (Industry Level) AnalysisSection 7 Global Longevity and Anti-senescence Therapy Market Segmentation (Channel Level)7.1 Global Longevity and Anti-senescence Therapy Market Segmentation (Channel Level) Sales Volume and Share 2014-20197.2 Global Longevity and Anti-senescence Therapy Market Segmentation (Channel Level) AnalysisSection 8 Longevity and Anti-senescence Therapy Market Forecast 2019-20248.1 Longevity and Anti-senescence Therapy Segmentation Market Forecast (Region Level)8.2 Longevity and Anti-senescence Therapy Segmentation Market Forecast (Product Type Level)8.3 Longevity and Anti-senescence Therapy Segmentation Market Forecast (Industry Level)8.4 Longevity and Anti-senescence Therapy Segmentation Market Forecast (Channel Level)Section 9 Longevity and Anti-senescence Therapy Segmentation Product Type9.1 Hemolytic Drug Therapy Product Introduction9.2 Gene Therapy Product Introduction9.3 Immunotherapy Product Introduction9.4 Other Stem Cell Therapies Product IntroductionSection 10 Longevity and Anti-senescence Therapy Segmentation Industry10.1 Hospital Clients10.2 Medical Service Institution Clients10.3 Drug and Device Sales ClientsSection 11 Longevity and Anti-senescence Therapy Cost of Production Analysis11.1 Raw Material Cost Analysis11.2 Technology Cost Analysis11.3 Labor Cost Analysis11.4 Cost OverviewSection 12 Conclusion

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