StemCell Therapy

Longevity Workouts: The Exercise Routines That Promote Wellness and Long-Life :What we know about health and the natural world changes all the time. One constant is that exercise is good for the body. Everyone knows this. But some exercises are much more effective than others, for reasons we are only slowly coming to understand.

This article is about so-called longevity workouts. Exercise that is if done often and long enough keeps the muscles and our immune systems younger for longer, and may even put another decade on our life expectancies. It is also about how they work, on a molecular level, to work the way they do.

It all starts with an ancient survival mechanism, one that we and all life on Earth inherited from the earliest single-celled organisms.

Imagine the scene 3.5 billion years ago the Earth is nothing but a steamy, volcanic rock filled with rock pools and salty oceans. Inside the rock pools are the first single-celled organisms and they are reproducing and evolving, much like life continues to evolve today.

It is reckoned that one of these cells evolved an adaptation that allowed it to stop reproducing when times are hard, and hunker down and enter repair mode. So whenever disaster struck a dry period that threatened the rock pool the one cell that figured out how to hunker down survived, while everything else died.

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It is now believed we are all descended from this ancient organism, and as a result we all carry within us the two functions that are reproduce or repair.

Reproduce mode is a loose word that means, when there is no immediate threat, we tend to relax; take things easy and enjoy ourselves. Repair is the opposite. Whenever we sense danger, we take action to save ourselves from the threat.

The conveniences of modern life have largely stripped away the need to be in repair mode often. We no longer have to hunt for food. In fact, food is so cheap and abundant that obesity is a major problem all around the world. The result is that we are almost always in reproduce mode. The problem is, our bodies never evolved for a life of such relative leisure, and it is detrimental to us in the long run.

According to the most compelling theory of the day, the information theory of ageing, we age due to a loss of information over time mostly through accumulations in DNA damage. Our bodies try to fight this loss by activating our so-called longevity genes. Scientists have identified seven longevity genes to this day, and they work like little first-responder teams. Meaning as soon as they detect DNA damage, they rush out to repair it.

The problem is these longevity genes work best when the body sounds the alarm for them to come out. That is, when the body is under mild stress. We put our bodies under mild stress through exercise. The problem is we dont do enough of it, and therefore we inhibit our longevity genes from repairing broken DNA and keeping us young.

Not all forms of exercise place our bodies under mild stress. A leisurely walk is great, but it does not stress the body. Neither does a casual swim or a jog if it isnt at least a bit strenuous. We put our bodies under mild stress through high-intensity training. More specifically, high-intensity interval training.

This can be as little as a 15-minute jog a day, as long as it is fitted with bursts of high intensity. But studies have shown that jogging for 30 minutes a day, five days a week can keep the body perhaps a decade younger over a lifetime.

You will know a workout is stressful when afterwards, your heart is beating out of your chest; you cant put a sentence together without stopping for breath, you are sweating, and if your breathing patterns are deep and rapid. This is known as the hypoxic response. Whenever we work out in this way, our bodies are tricked into thinking there is an emergency, and so our longevity genes kick into action. We are in repair mode.

Other conditions put our bodies under mild stress, and when combined with HIIT exercise, they can have great results. Uncomfortably cold temperatures force the body to burn energy in order to prevent our core temperatures from dropping. This also forces the longevity genes into action. So a good way to double benefit would be to exercise in the cold. Even a brisk walk around the block on a winters day will kick start the longevity genes.

Another is so-called amino-fasting while you exercise. This does not mean not having amino acids, it just means getting all of them from plant-based foods and not meat. Most meat eaters consume too many amino acids already. By eating the right plant-based foods, it is easy to get all the necessary amino acids, but the body will respond to the sharp drop of abundant amino acid intake from meat as though there was an emergency.

All of the above methods are great for inducing mild-stress. Together they are even more effective at calling out our longevity genes to repair DNA, thereby slowing the ageing process and keeping us healthier and younger.

But it is important to emphasise mild stress. Exposing yourself to the deep cold for long periods of time is not mild stress, it is very dangerous. Likewise, with amino-fasting, starvation and mal-nourishment is also very bad. It is also important not to overwork yourself through exercise, either. All you want is that mild stress feeling. Its a temporary discomfort that fades in minutes. Chase that again and again, and expect to add years of youth and health on to your life.

Author :

Neil Wright is a writer and researcher. He has an interest in travel, science and the natural world, and has written extensively about longevity and health on his website.

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Longevity Workouts: The Exercise Routines For Wellness and Long-Life - Women Fitness

She has become one of the UKs best known ballerinas thanks to her roles with the Royal Ballet and as Victoria the white kitten in Tom Hoopers Cats movie. But Francesca Haywards new performance, filmed in lockdown, is about how it has felt to not perform at all during the Covid-19 pandemic.

Hayward is one of five dancers in a new short film, Where We Are, choreographed by and co-starring Ramberts Hannah Rudd. The stylish black-and-white piece, released online on Thursday morning, captures our thoughts and feelings at being unable to perform, unable to create, says Hayward. But also going deeper, for me, it allowed me to express my fears and concerns for my family and their health.

Hayward has already shared a number of short dance videos during lockdown in which she duets with her partner, Cesar Corrales a first soloist at the Royal Ballet so she is used to self-filming. Her contribution to Where We Are was recorded on her iPhone. The film was co-created by the producer-director Anthoula Syndica-Drummond and Royal Ballet dancer Alexander Campbell, who also appears alongside Clemmie Sveaasand Jeffrey Cirio. With the five dancers filming themselves at home, one of the major challenges was matching the lighting and frame sizes, says Campbell, who has known Rudd since they were at the Royal Ballet school. To match Rudds choreography, which he says has a wonderful honesty and humanity, an original music score was commissioned from composer Sophie Cottonand played by violinist Naomi Burrell.

Hayward said that she has been able to take online classes with the Royal Ballet over the last few weeks but that swapping the companys huge studio for her own living room has meant that it is hard to perform at the same level and maintain her usual fitness. She installed her own barre at home and has a Harlequin dancefloor square: It has been a massive help to have those two pieces of equipment. She said that it can be daunting for dancers to return to performing on stage in front of an audience and that it will take time to get back into the shape that allows us to work at our maximum. However, she pointed out that this period of rest can also be beneficial to dancers. You very rarely get anything more than a few weeks off at a time as a dancer, so to have an extended period is incredibly valuable for longevity.

Campbell says the project has bridged the gap caused by the coronavirus, enabling him to collaborate again with old friends and also work for the first time with other creatives. While venues are closed, he hopes that the many online dance films such as Matthew Bournes mini version of The Red Shoes will bring the artform to a new audience.

Art, says Hayward, can lift people in dark times and enables you to escape, enjoy, learn and explore. Like her colleagues, she is fearful of the long-term impact on the industry. With auditoriums closed, most theatres and companies have little income, she said. The uncertainty is the biggest fear for everyone involved.

On Saturday, however, Hayward and Corrales will finally return to the Royal Ballets stage for Live from Covent Garden, one of a series of free streamed broadcasts and the first live performance from the Royal Opera House since its doors closed on 17 March. They will perform a ballet interlude, newly choreographed by Wayne McGregor, as part of a programme of music. The duet has given them both positivity and hope says Hayward. It brings a freedom and relief.

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Cats star Francesca Hayward on fear, lockdown dancing and her return to the stage - The Guardian

Larry Deckerhoff, trusted adviser to companies and entrepreneurs in The Woodlands (Texas), announced the continuation of The Woodlands Lunch Forum Series with a luncheon event scheduled for Friday, 10 July 2020 atAmerigos Grille25250 Grogans Park Drive in The Woodlands. The Forum is scheduled to start at 11:30 AM and last an hour and a half. Mr. Deckerhoff indicated,

The theme of this Lunch Forum is Advanced Health for the New Millennium, Immunotherapy and Rejuvenation Focus on Supercharged Immune Systems During Troubled Times. Among our featured speakers will be Ralph Fucetola JD, President of The Woodlands own Institute for Health Research. He will be joined by two experts in rejuvenation and immunotherapies. The short presentations will leave plenty of time to reconnect and enjoy the extraordinary cuisine at Amerigos Grille.

Interested participants are requested to RSVP to stephen.contreras1@hotmail.com the requested donation of $70.00 includes a three course gourmet lunch. Donations in excess of luncheon value are tax-deductible.

Speakers include: Ralph Fucetola JD President, the Institute for Health Research http://www.InHeRe.org Bill Hayes, NutraSpace http://www.NutraSpace.com Elliot Gorog, Health Matching Accounts http://www.healthmatchingaccounts.com

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Lunch Forum Reopens: The Woodlands Lunch Forum to Host Longevity and Health Event - Woodlands Online

THE WOODLANDS, TX - Larry Deckerhoff, trusted adviser to companies and entrepreneurs in The Woodlands (Texas), announced the continuation of The Woodlands Lunch Forum Series with a luncheon event scheduled for Friday, 10 July 2020 at Amerigos Grille, 25250 Grogans Park Drive in The Woodlands. The Forum is scheduled to start at 11:30 AM and last an hour and a half. Mr. Deckerhoff indicated,

Meet You After the Pandemic Reopening

The theme of this Lunch Forum is Advanced Health for the New Millennium, Immunotherapy and Rejuvenation Focus on Supercharged Immune Systems During Troubled Times. Among our featured speakers will be Ralph Fucetola JD, President of The Woodlands own Institute for Health Research. He will be joined by two experts in rejuvenation and immunotherapies. The short presentations will leave plenty of time to reconnect and enjoy the extraordinary cuisine at Amerigos Grille.

The Institute, which was founded in 1998, and focuses on leading edge, natural and nutritional support for vigorous aging and powerful immunity, announces the reopening of its The Woodlands office.

The Institute President will introduce advanced approaches to health and longevity through the featured speakers who are positioned to inform and enlighten, in cooperation with NutraSpace, Health Matching Accounts and Natural Solutions Foundation.

Interested participants are requested to RSVP to stephen.contreras1@hotmail.com the requested donation of $75.00 includes a three course gourmet lunch. Donations in excess of luncheon value are tax-deductible.

Speakers include: Ralph Fucetola JD President, the Institute for Health Research http://www.InHeRe.org Bill Hayes, NutraSpace http://www.NutraSpace.com Elliot Gorog, Health Matching Accounts http://www.healthmatchingaccounts.com

The President of the Institute concluded:

We look forward to a growing presence in The Woodlands community as our alliances with local and regional companies and researchers continue to mature. Our research interests include areas as diverse as longevity nutrition, immunotherapy and autism retrieval. While we expect that the latest pandemic from China, COVID-19, will be contained, holistic approaches to stimulating natural immunity remain highly relevant and are a significant area of Institute interest.

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Lunch Forum Series Reopens: The Woodlands Lunch Forum Series to Host Longevity and Health Event July 10th at Amerigo's Grille - Woodlands Online

Part 16 of our 90-part series assuming the roster does not change before we are complete which will break down each player of the Steelers current 90-man roster in alphabetical order. This series will encompass many aspects of each players game and their current role with the team. At the end, Ill give some projected stats as well as their chances to make the 53-man roster.

This time we spotlight Steelers Long Snapper:

Position: LSHeight: 6 4Weight: 245 lbsCollege: Portland StateDraft: UDFA, 2016 (Cardinals)

16 Games played

Expires in 2021

$1,135,00 salary cap number (0.57% of total cap)

$450,000 dead money

$685,000 cap savings if cut

Lock. Believe it or not Canaday actually has some competition heading into camp, linebacker/long snapper Christian Kuntz. That being said, cutting Canaday would set the team back nearly $500k so I highly doubt hes going anywhere unless he completely forgot how to snap the ball.

Hows this for expert analysis, I predict Canaday won't botch a single snap... Long snapping stats are fun... Give me a break...

16 Games played

Kameron Canaday, has been a fine long snapper for the Steelers. The best thing we can say about him is that we haven't had to talk about him since he came to the team in 2017. Much like his predecessor, Greg Warren he has been consistent and low maintenance. You can't ask for anything more from your long snapper.

Ola AdeniyiMarcus AllenTyson AlualuTrajan BandyZach BannerJ.T. BarrettJohn BattleJordan BerrySaeed BlacknallBreon BordersChris BoswellAntoine Brooks Jr.Isaiah BuggsDevin BushDeon Cain

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Will long snapper Kam Canaday have the longevity as Greg Warren? - Behind the Steel Curtain

Insurance and reinsurance broker and consultancy Aon has warned UK pension schemes not to over-react to the recent short-term spike in mortality rates in the country, as the impact to longevity risk assumptions may not be as significant as it seems.Aons Risk Settlement Group, which deals with pension risk transfer, including the buy-in and buy-out side as well as longevity reinsurance and longevity swaps, says that overall the longevity markets are continuing to function effectively despite the impacts of COVID-19.

Of course, the Covid-19 coronavirus pandemic has caused a significant spike in excess mortality rates in almost every country affected. In the United Kingdom the increase in excess mortality as a result of the pandemic has been among the highest, with the country perhaps the hardest hit.

Aon does not believe this warrants any significant changes in assumption over the forward-mortality rate at this time, though.

Instead, the broker cautioned UK pension schemes against over-reacting to the elevated short-term mortality data when it comes to setting their long-term mortality assumptions.

Tim Gordon, partner and head of Demographic Horizons in Aons Risk Settlement Group, explained, Were emerging from the initial wave of the global COVID-19 pandemic with no effective vaccine and with some critical aspects still unknown. Some people may therefore assume that life expectancy must have reduced, but this is not necessarily the case.

While there are potential outcomes of this crisis that could reduce life expectancy, including the possible impact of economic recession, there are also potential outcomes that could result in higher life expectancy. These could include increased spending on health and social care, and a potential hardening of the UK to future pandemics.

Pension schemes look closely at mortality rate data, modeling and indications to help in setting their assumptions related to longevity risk exposure and also funding needs.

Decisions related to entering into pension risk transfer are made on these basis, while longevity exposure drives the need for hedging and de-risking solutions to reduce exposure to pensioners living longer than anticipated.

So, with excess mortality rates having spiked due to the Covid-19 pandemic, pensions may be thinking they can reduce their longevity assumption and expect to offset longevity de-risking decisions, but this isnt necessarily the case.

Gordon continued, On top of this, the socio-economic profile of pension schemes means that their liabilities are typically partially insulated from the variations we see in national mortality statistics. Accordingly, it would be premature now to make major changes to best estimate longevity assumptions in either direction. Indeed, it is reasonable for median best estimate assumptions to remain broadly unchanged.

Martin Bird, senior partner and head of Aons Risk Settlement Group, added, Longevity markets have continued to function efficiently over the course of the crisis to date, with bulk annuities and longevity swap transactions continuing apace. Trustees and sponsors have, in our experience, taken the view that risk settlement forms part of their long-term risk management strategy and have been comfortable with proceeding with transactions, despite the turbulence from COVID-19. In fact, in some cases, agile clients have been able to take advantage of pricing opportunities, such as those arising from increased credit spreads earlier in the crisis.

More than ever, it is important for schemes to keep their wits about them when entering a potential transaction. Particular features in the current environment are the need to understand the consequences of different on-risk dates and the potential for regret risk as well as ensuring that investment portfolios are adequately stress-tested to guard against any later liquidity problems.

Reinsurance markets remain open for longevity risk transfer and pension de-risking business at this time, with this area of the market well-capitalised still and likely to continue to be for the foreseeable future.

However, the capital markets still remains ready to assist to a degree and there continues to be appetite for longevity exposure in some life ILS fund strategies.

Read about many historical longevity swap and reinsurance transactions in our Longevity Risk Transfer Deal Directory.

Excerpt from:
Aon warns pensions not to over-react to Covid-19 mortality spike - Artemis.bm

Breaking into the wine business is no easy feat especially if youre Black. In fact, there are only approximately 50 black-owned wineries globally, so the journey from winemaker to now president of the Association of African American Vintners was of course met with many challenges.

But none of them could stop Phil Long.

Not even a global pandemic or the loss of his wife and co-founder, Deborah, a year ago to cancer.

Through blood, sweat and tears Long was able to push their dream forward, and fulfill what they started in a garage years ago with the creation of Longevity Wines what he likes to call, a love infused brand. Now with a unique partnership with Bronco Wine Co., the makers of Charles Shaw wines for Trader Joes, Long is able to spread the love and distribute his cabernet sauvignon and chardonnay nationally.

In this interview with ESSENCE, Long shares the inspiration behind his new collection, his hopes for making the wine industry more inclusive and further plans for expansion.

You began your wine journey making wine in the garage with your wife Debra. Because Longevity is defined as a love-infused brand is it inspired by her?

The Longevity brand is absolutely inspired by Debrashe even came up with the name. When I suggested Long Family Cellars, she asked me to look around and tell her what part of our family was helping us make wine? Obviously, the name became Longevity, which is both a play on our last name and a reference to our enduring love for each other and for sharing great wine.

When Deborah and I were dating, I started giving her glass hearts for Valentines Day. Everything in her life became hearts: heart rocks, heart jewelry, heart everything. When we rebranded in 2009, I designed the current label with the intricate heart that contains more hearts along with grapevines and grapes to truly represent who we are. Today, that heart is the icon of our brand and the symbol of our love story.

What makes Longevity stand out against the rest?

Its the heart on the bottle that draws people into our love affair with wine and with each other. Then, they celebrate their own love stories with the delicious wine inside. But its not just about the brand, which has been in many TV shows and movies, its also the fact that this $16 wine competes in the rating arena with wines priced upwards of $50.

What was the creative process behind developing the Longevity collection?

At some point in our journey, we decided that we should have at least one wine named after each family member; that meant one for Debra (Deb-ru-vee), one for me (Phil-osophy) and one for our precious little Havanese pup, PressTon. We still have those three wines on the tasting menu today. They represent no less than 10 different varieties of grapes we use to blend and also to make single varietal wines depending on the quantity available. Those wines have become our signature wines.

What are the changes you feel the wine industry needs to make to be more inclusive?

The fact is African American winemakers make up only one tenth of one percent of the wine industry. In the world of statistics, that rounds down to zero. I think we need to focus on increasing awareness of the fact that African American winemakers do exist and that we produce great wines. Id like to see wineries across the country building a diverse workforce with education programs, internships and scholarships.

Whats one thing about wine that you want to educate Black people on?

In my parents house, there was this tall bottle of Chianti with a basket bowl at the bottom of it. Thats about all I knew about wine growing up. When I went to college, I didnt even know that wine was an industry or a career path. I would like to educate not only African Americans about the world of wine, but all Americans who dont have access to information about this delicacy and its industry. Wine can be a rewarding career.

How do you plan on expanding your company?

Longevity is in the fortunate position to have partnered with Bronco Wine Company to launch our brand nationally. I am now producing California wines on a much larger scale to meet the needs of a national brand. We are still producing our reserve wines in our Livermore Valley facility and every bottle of nationally distributed wine encourages customers to visit our Livermore Valley tasting room.

Continue reading here:
Black Winemaker Launches 'Love-Infused' Wine After Loss Of Wife - Essence

Pandemic trends show that despite some restrictions many countries are experiencing, were still finding many ways to move. According to Garmin trends data, yes. Most of the worlds daily step count has decreased significantly. However, this is not the whole picture, since many people have developed new routines with different types of exercises to stay active. So just because were experiencing a pandemic, it doesnt mean were sitting on our behind all day.

There has been a massive shift in the way people are moving across the globe. An earlier report by Garmin saw remarkable changes in the types of sports and exercises people were choosing to do. Moreover, Garmin states that simply looking at the step count wont tell a complete story. We know that this number is down in every country, but it doesnt necessarily mean people are exercising less. Think about it. There could be a lady who lives in a tiny flat in Italy, who hasnt been able to walk much at all. But we dont know what shes doing in her flat to keep active. For all we know, she could be cycling indoors for 20km a day. Thats why Garmin has taken this into consideration in their new pandemic trend report. In fact, it could even mean that many people are moving more.

We need to get an accurate picture of how people are moving around the world. Fortunately, Garmins wearable devices can tell us how people are moving, and not just if theyre moving. We do know that the total worldwide steps decreased by 12% in April 2020. However, steps from just workout activities increased by 24%. This means that more people are exercising but in different ways. This makes up for the suppression of normal daily movement during the pandemic.

Its crazy to think that years from today, were going to look back at this pandemic and remember April as the month COVID-19 hit us. Coronavirus extended its debilitating reach to nearly every country, culture, and community on Earth. Theres no denying the fact that the pandemic has impacted our daily lives phenomenally. Besides that, we thought it would be interesting to report back on the effects its having on human activity.

According to the Garmin report, we see a clear reflection of the pandemics crippling global power. Especially when you compare April 2020 to April last year. Aggregated data from millions of Garmin users shows a worldwide decrease of 12% in average daily steps.

Note that Garmin applied a fixed data scale to every country in the world. For this reason, results are magnified for countries with lower population counts and stricter stay-at-home orders. For example, the U.S. compared to Uzbekistan. While Uzbekistan is nowhere near the U.S. in the number of coronavirus cases. It has a bigger percentage decrease because there are fewer people and stricter lockdown rules.

Although the data shows were not walking as much as before, we are moving quite a bit. People are keeping fit during this pandemic, by completing home workouts and other forms of activity to compensate. We cant deny the fact that its certainly become a lot more interesting when it comes to exercise. People are demonstrating a lot of creativity.

We can see that theres a clear reduction in general movement, but when we take a deeper look at the data. Things get a bit more enticing. Garmin reports that a portion of these total worldwide steps come from uploaded activities like running, cycling and hiking. With 20 built-in activity apps on Garmin devices, they were able to accurately detect this data.

This means that if we look at just the steps coming from these logged activities. We can find the opposite trend.On average, steps from logged activities were up 24% worldwide. To sum up, people have started to engage in unique exercise activities to make-up for lost steps in their everyday routines. Not bad for being locked in your home due to a pandemic.

Whether its true, pandemic or not, come hell-high-water, people are getting their exercise in.

The question remains, what is everybody doing to stay fit during the pandemic?

Based on the data, its clear that Garmin users are turning to activities that are most viable depending on their geographic location. Some of these activities are highlighted in our previous post on pandemic trends inthe U.S. and Europe. However, this new data gives us a complete global picture.

The picture below shows activities that saw the largest increase in each country. This is when we compare April 2020 to April 2019.

From what we can see, it seems that most countries have taken to indoor cycling. Apparently, Australians and Canadians both seem to agree that walking is the best activity during life in quarantine. But China, Mexico, South Africa and a handful of other countries have all turned to fitness equipment workouts. But what kind of fitness equipment workouts? Garmin says that indoor cardio accounts for 50% of these workouts. Last year duringDuring the same time period, over 50% of the activities in this category were strength training. Thats very interesting, the pandemic has definitely forced people to make adjustments to their usual routine.

Remember when everybody was raving about strength training? Well, now we have to adapt and look into doing some more cardio too. Moreover, this shift indicates that weve made a shift from gym-structured workouts to home-based find-a-way workouts. Although its evident that a vast majority of people cycle indoors, Garmin took it a step further. They decided to consult a couple of Garmin pro athletes to collect some qualitative context. Interestingly, they said that certain areas like France are not able to cycle outside. says U.S. triathlete Taylor

As a result of the pandemic, many who never did indoor cycling are now doing it five times per week.

The triathlete also said that many athletes are spending more time on platforms like Zwift. He said that their training group meets once every 2 weeks to do a session together. Its a great way to keep yourself motivated to keep moving when having regular virtual sessions. Moreover, its a wonderful way to remain in contact even if it is only once a week. This is particularly important if youre used to meeting regularly with your training group of workout buddies at the gym.

Whilst the pandemic has pushed humanity toward some activities, it has decisively turned it away from others. In a previous article that focused on European trends, it noted that swimming had all but disappeared. As we compare April 2020 to April 2019, this looks to be a global trend too. The data shows significant decreases in swimming activity from the Americas to the Far East.

However, this doesnt mean that swimmers are just sitting all day. The data shows that in Australia 54% of the users who swam in April 2019 are instead running outdoors in April 2020. Then in China, 43% of the users swamin April of last year they were either running or cycling outside this year. In the U.S., pro triathletes are keeping up their fitness by working hard at home. Since most public pools are closed, theyre doing more gym-based strength workouts. If youre a swimmer, then you can even try to replicate some movements and muscle patterns of swimming.

When it comes to multisport training, hiking and golf theres been a massive decrease in multiple countries. But like swimmers, these guys are looking for alternatives. For example, in South Africa, 20% of the users who were golfing in April 2019 turned to indoor fitness workouts in April 2020. And then another 11% began indoor cycling.

The consensus seems to be that people are using this time to their advantage. Particularly if youre an athlete, wed imagine youre using this pandemic to prepare your body for when sports return. Its important to try to maintain your usual activity levels even if it means trying something new.

In conclusion, its obvious that we are finding a way to move no matter what. From the mainstream to a professional athlete, people are adapting routines but clearly not stopping them. If youre a runner but used to enjoy running with your teammates, then try listening to some podcasts or audiobooks while you run. Theres always a way to work around this pandemic.

Hold tight guys, team sports will return eventually. But for now, finding other ways to move on your own is your best bet. Fitness is just one of millions of routine adjustments being made around the world.

Snacking all day, making constant trips to the fridge? Yeah, we totally get where youre coming from.

The Impact of the Global Pandemic on Human Activity: Part III. Garmin. https://www.garmin.com/en-US/blog/fitness/the-impact-of-the-global-pandemic-on-human-activity-part-iii/

The Global Pandemic and Active Lifestyles: Part II. Garmin. https://www.garmin.com/en-US/blog/general/the-global-pandemic-and-active-lifestyles-part-ii/

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pandemic-restrictions-arent-stopping-us-heres-what you need to know - Longevity LIVE

Due to the pandemic, we have included a special section on the Impact of COVID 19 on the Longevity and Anti-senescence TherapyMarket which would mention How the Covid-19 is Affecting the Industry, Market Trends and Potential Opportunities in the COVID-19 Landscape, Key Regions and Proposal for Longevity and Anti-senescence Therapy Market Players to battle Covid-19 Impact.

The Longevity and Anti-senescence TherapyMarket report is one of the most comprehensive and important data about business strategies, qualitative and quantitative analysis of Global Market. It offers detailed research and analysis of key aspects of the Longevity and Anti-senescence Therapy market. The market analysts authoring this report have provided in-depth information on leading growth drivers, restraints, challenges, trends, and opportunities to offer a complete analysis of the Longevity and Anti-senescence Therapy market.

Top Leading players covered in the Longevity and Anti-senescence Therapy market report: CohBar, TA Sciences, Unity Biotechnology, AgeX Therapeutics?Inc, PowerVision Inc. and More

Get PDF Sample Report With Impact of COVID-19 on Longevity and Anti-senescence Therapy [emailprotected] https://www.marketinforeports.com/Market-Reports/Request-Sample/83332

The report offers clear guidelines for players to cement a position of strength in the global Longevity and Anti-senescence Therapy market. It prepares them to face future challenges and take advantage of lucrative opportunities by providing a broad analysis of market conditions. the global Longevity and Anti-senescence Therapy market will showcase a steadyCAGR in the forecast year 2020 to 2024.

Product Type SegmentationHemolytic Drug TherapyGene TherapyImmunotherapyOther Stem Cell Therapies

Industry SegmentationHospitalMedical Service InstitutionDrug and Device Sales

Our Complimentary Sample Longevity and Anti-senescence Therapy market Report Accommodate a Brief Introduction of the research report, TOC, List of Tables and Figures, Competitive Landscape and Geographic Segmentation, Innovation and Future Developments Based on Research Methodology.

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Regions Covered in the Global Longevity and Anti-senescence Therapy Market: The Middle East and Africa (GCC Countries and Egypt) North America (the United States, Mexico, and Canada) South America (Brazil etc.) Europe (Turkey, Germany, Russia UK, Italy, France, etc.) Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)

Years Considered to Estimate the Longevity and Anti-senescence Therapy Market Size:History Year: 2015-2019Base Year: 2019Estimated Year: 2020Forecast Year: 2020-2024

Highlights of the Report: Accurate market size and CAGR forecasts for the period 2019-2024 Identification and in-depth assessment of growth opportunities in key segments and regions Detailed company profiling of top players of the global Longevity and Anti-senescence Therapy market Exhaustive research on innovation and other trends of the global Longevity and Anti-senescence Therapy market Reliable industry value chain and supply chain analysis Comprehensive analysis of important growth drivers, restraints, challenges, and growth prospects

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COVID-19 Update: Global Longevity and Anti-senescence Therapy Market is Expected to Grow at a Healthy CAGR with top players CohBar, TA Sciences, Unity...

Electric motor on a Tesla Model X full electric car chassis demonstration model on display at ... [+] Brussels Expo in Brussels, Belgium. The platform is fitted with the electric motors for the rear and front wheels and shows the empty space in the middle where the battery packs are fitted on the production models. (Photo by Sjoerd van der Wal)

Concern over the longevity of the batteries powering Tesla electric cars seems to waning as the stock price pushes ever higher, and the Californa-based (for now) carmaker may soon offer drivers even more security in the form of a battery that will last for over a million miles worth of driving.

Chinese battery maker Contemporary Amperex Technology, better known as CATL, which inked a supply deal with Tesla in February, claims it is ready to produce a new battery that will likely outlast an owners time with the car - a situation that has ramifications beyond just driving on electricity.

To be clear, CATLs battery tech doesnt give drivers a million miles on a single charge (that day is still a ways off), rather, the company claims that the battery will work for over 1.2 million driven miles over the course of sixteen years, or about 75,000 miles a year. Driving range will ultimately be determined by the size of the battery pack fitted to the car, but current Tesla models are giving drivers between 250 and 390 miles of range before needing a recharge. depending on configuration and model.

Most car owners in the U.S. drive their cars less than 20,000 miles per year on average. According to the BBC, most EV makers currently warranty their batteries for 60,000 to 150,000 miles.

CATL says it has a two-year contract with Tesla to start putting the new battery in Model 3 units. Terms of the contract were not specified. A company spokesperson told Bloomberg that they stand ready to begin production pending any orders they receive and that the new battery will be a 10% premium over their regular offerings. The BBC reports that CATL is looking to start producing batteries at a plant to be constructed near the German town of Erfurt in 2021. Tesla is also building a new Gigafactory in Germany and hopes to have it up and running in 2021. CATL also indicated they will offer the new batteries to car companies besides Tesla.

After The Car

While a million mile battery sounds impressive, its unlikely that a large number of electric car owners will ever drive their vehicle that distance, and in time, the rest of the vehicle may end up as unusable due to wear and tear, accidents or other service-ending reasons. At the point, the still-useful battery could find service in another role - or possibly in another vehicle as a used electric vehicle market begins to form. The batteries could also be repurposed as home energy storage units or as part of a large-scale battery array that provides power to a community or as power backup for a remote hospital.

The Electric Achilles Heel - For Now

Electric cars (and soon: trucks) continue to gain in popularity, with the now-obvious benefits of impressive performance, quiet operation, less maintenance and low operational costs becoming selling points. But the key component of electric vehicles - the battery - still needs to overcome several hurdles before it can compete squarely with gas-driven machines. Battery costs, charging times, capacity and longevity remain challenging technological problems, and while those problems will likely be solved in the next decade or so, the companies that can up with the solutions stand to reap enormous rewards as all sectors of transportation begin to shift away from fossil fuels. The quest for ever better batteries is driving research and innovation at numerous companies around the globe, with an almost unlimited market as the prize. CATLs battery tech is yet another possible step towards that eventual future.

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Chinese Company Linked To Tesla Says It Is Ready To Start Making Million-Mile EV Battery - Forbes

PORTSMOUTH Portsmouth City Council met Monday for their first meeting open to the press and public since COVID-19 precautions were established in March.

Council members and those present still practiced social distancing while the meeting took place at the Shawnee State University Ballroom. Council dispensed of the reading of the journal for May 26 and excused the absent member of council Tom Lowe.

From the legislative portion of the meeting council passed for first reading an ordinance enacting a new Chapter entitled Discrimination Prohibited, of the Codified Ordinances of the City of Portsmouth establishing a procedure to protect and safeguard the right and opportunity of all persons to be free from all forms of discrimination, including discrimination based on age, race, color, creed, religion, national origin, ancestry, disability, marital status, gender, gender identity or expression, sexual orientation, or physical characteristics and an ordinance amending Section 125.03 (K) Procedures to Determine the Lowest and Best Bid for Construction of Public Improvements of the Codified Ordinances of the City of Portsmouth, Ohio, an Ordinance amending Chapter 171- Fair Housing Practices of the Codified Ordinances of the City of Portsmouth, Other items passed for their respective readings included an Ordinance amending Chapter 171- Fair Housing Practices of the Codified Ordinances of the City of Portsmouth, and an ordinance amending Section 541.08 Ethnic Intimidation of the Codified Ordinances of the City of Portsmouth.

An Ordinance authorizing approval of the consent legislation submitted by Ohio Department of Transportation (ODOT) determining the need for a guardrail project to update Type A end treatments along NHS routes within the corporation limits of Portsmouth and an ordinance authorizing the acceptance of the United States Department of Justice, Office of Justice Programs, Bureau of Justice Assistance funding, under the Edward Byrne Memorial Justice Assistance Grant (EBMJAG) to establish a dedicated account for this grant and to authorize the appropriation of such funding as received, and an ordinance authorizing the acceptance of the United States Department of Justice, and An Ordinance authorizing the employees in the positions of Police Chief and Fire Chief be afforded the same rates for longevity as bargaining unit members within the respective departments were each waived of the three reading rule and were passed by council.

An item added to the agenda to amend the salary ordinance as amended by ordinance no. 87 of 2019 to reflect a 2.75% wage increase for FOP lodge no. 33 and a 2.5% for ASME local 1039 received as of Jan. 1 2020 a 2.75% wage increase retroactive to Jan. 1 2020 for nonunion employees longevity increases to nonunion employees as authorized per ordinance no. 66 of 2017, the addition of parks of recreation director per ordinance no. 71 of 2019 and a wage increase for position of police chief as per 2020 budget ordinance no. 7 and repeal ordinance no. 87 of 2019 was also passed for a first reading by council.

During statements and remarks from citizens regarding items not on the agenda, Sharon Bender addressed council in regards to the death at the Scioto County Jail. Bender said that although the issue is that of the county, people arrested by the Portsmouth Police also go to the jail. There are a lot of questions that need answered, and I think all people within the city of Portsmouth should be concerned that a man has died. I dont really know how more too express other than I think there are irregularities in the photos Ive seen of the man, said Bender. Bender stated that everyone in Portsmouth should be concerned because there is potential for family members of anyone in Portsmouth to find themselves at the jail and that we must demand answers and for the situation to be further addressed. Carrie Duncan also addressed council and voiced her concerns for systematic racism, calling on members of council to use their positions to promote unity.

During his Mayors report, Councilmen Johnson suggested that council be given each a copy of Ms. Duncans questions to answer during next meetings conference in order to follow Sunshine Laws.

Reach: Ivy Potter (740) 353-3101 Extension 1932

2020 Portsmouth Daily Times, all rights reserved

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Council resumes meetings open to the public - Portsmouth Daily Times

Celebrities and public figures using Photoshop is a common occurrence. But when its Queen Elizabeth accused of sharing altered photos, its sure to raise a few eyebrows.

The photo in question got posted to the official British royal family Instagram account on June 10 in honor of Prince Philips 99th birthday. Its a milestone birthday even by royal family standards and theyre known for longevity.

The picture of the queen and Philip standing outside Windsor Castle is making rounds on social media not because the Duke of Edinburgh turned 99, but rather because many royal fans are saying its a total fake.

Part of the reason the photo became instantly popular is that Her Majesty and Prince Philip dont take many photos together anymore, especially after the Duke of Edinburgh retired from his public duties in 2017. The picture is the first glimpse of Prince Philip since he was spotted leaving a London hospital on Christmas Eve 2019.

Meanwhile, Queen Elizabeth is still very active in public life and ruling even during the current global pandemic.

At first glance, the Duke of Edinburghs birthday snapshot looks totally normal. He and Queen Elizabeth are standing on the lush, green lawn of Windsor Castle where she and her husband have been holed up since quarantine guidelines became mandatory.

But upon closer inspection, fans are noticing that theres somethingstrange about the picture. Theyre saying it looks like a bad Photoshopattempt.

Look at [the queens] hands its clearly photoshopped. I havea feeling they werent even physically together for this photo, one Facebook userin a royalfamily fan group shared. The more I look at it the more I can see what is wrong withthe photo, another agreed.

The main complaint about the photo is that the shadows on Queen Elizabeth and Prince Philip dont match the sunny background, giving it an odd appearance that seems fake. Could it be that the photo was taken in front of a green screen with the backdrop added later? Maybe.

My guess is that they took the picture indoors and thensuperimposed it over the outdoors of Windsor Castle. Either that or its somesort of 3D photo, one commenter explained.

Others claim the couple looks too healthy in the picture. They are too young in that pic. He is much more frail, another person said. Am I the only one who thinks he had his jacked padded to appear healthier? one follower wondered. Philips hair looks touched up too! added another.

Between the global pandemic and civil unrest, people are feeling very nervous all around the globe. The royal family released the photo partly to celebrate the Duke of Edinburghs birthday and partly to remind the United Kingdom that Her Majesty is still working and still in charge.

Photoshoppedor not, its a lovely photo and positive gesture from the royals.

Read the original here:
Fans Claim Queen Elizabeth and Prince Philip Posted a Fake Photo for His Birthday - Showbiz Cheat Sheet

We are Auburn Students and Community for Change. The purpose of the protest on Sunday, June 7, was to amplify the call to justice for the murder of George Floyd, Breonna Taylor, Tony McDade and the countless Black people who have lost their lives at the hands of police brutality.

We are heartbroken and enraged for every community that has lost someone to the cruelty of both the police and the systems that consistently and unremorsefully uphold the polices reign over Black lives.

Auburn Students and Community for Change would like to thank everyone for attending Sunday's protest and standing in solidarity with the Black community.

We would also like to extend our appreciation to the many people that have contributed to and supported the protest that were unable to be present with us. Your support does not go unnoticed.

Even though the protest on Sunday has ended, the Black Lives Matter movement and Auburn 4 Changes protest against police brutality, discrimination, and racism does not end here. If you care about this movement, we challenge you to take action every day to educate yourself and support organizations working toward equity and justice.

To our Allies:

Get comfortable with being uncomfortable as you stand in solidarity, advocate, and uplift Black voices within our community!

Please stop looking to Black people to fill voids in your knowledge about social and criminal injustice. You have the world wide web to educate yourself. Use it, and in turn, educate your non-Black peers.

Please continue or start calling out your friends, family, coworkers and professors making racist remarks or discriminating against minorities. You have the power to hold your city and University accountable, and to bring about drastic structural change.

By not speaking up you show that you agree. Continue to have discussions with Black people and practice Cultural Humility above all.

To the Black community:

Our voices will no longer be silenced! Our presence will be felt!

This is not a sprint but a marathon. We must continue to support each other and not give space to those who try to create division within our community.

Continue educating yourselves and finding where and how you can contribute to our movement.

We have a long history of Black liberationism and organizing to draw from, and our current mental health is also key for the longevity of our movement, locally and worldwide. Please continue to allow yourself to feel angry and demand change. It is time people are held accountable.

Lastly, remember why we all march. Remember what we fight for.

Yes, we fight for an end to police violence in the Black community. But even more, we fight against the insidious system of racism and oppression that gave rise to the violent policing culture that has existed so long. The insidious system upon which America, this state, and this city were built, and which must be dismantled to bring about a liberated world for all.

We fight against these systems so our children, and their children and their children after that can live in an America that is true to the values it has so long espoused.

The protest on Sunday has ended, but it was just one event. We ask: what are you doing today to combat systems of oppression? What will you do tomorrow? We have a long road ahead of us and a lot of work to do. Lets go.

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LETTER TO THE EDITOR | Sunday was just the beginning - The Auburn Plainsman

When Derrius Guice was selected from LSU in the second round by the Washington Redskins back in 2018, his fall from his expected draft position of the first round raised some eyebrows and led to discussions of if his off-field behavior was the cause for that fall.

While he was unable to suit up until 2019 due to a torn ACL suffered during the 2018 preseason, Derrius Guice is very much in the plans for the Redskins moving forward, and he fits perfectly into the plans for the longevity of their offense, being able to team up with quarterback Dwayne Haskins and wide receiver Terry McLaurin.

Derrius Guice suited up for five games in 2019, and even when he came back, he had to deal with incumbent RB Adrian Peterson as the bell cow back even with as long as he has been in the NFL.

Yet, with Derrius Guice coming into 2020 fully healthy, he still has to deal with a full stable of RBs looking for carries.

Besides Peterson and Derrius Guice, the team also has Stanford draftee Bryce Love (who has also dealt with ACL issues), former Seahawks scatback J.D. McKissic, former Tampa Bay Buccaneers back Peyton Barber, former Indianapolis Colts back Josh Ferguson, and rookie draftee Antonio Gibson out of Memphis. While they will most likely move forward with three to four of these backs for the regular season, nothing is promised for any of them.

Derrius Guice is the back with the most to prove on the roster, as his high draft status and pedigree should become the norm for this offense moving forward. His durability and longevity are going to be the biggest determining factors for how successful the Washington offense is this season, but if he remains healthy, he should be able to take over the starting role from Peterson and command lead-back abilities as soon as the first week of the season.

Both Haskins and McLaurin are going into their third seasons in the league, and they have been able to develop a solid rapport in the offense. While both were drafted in the same year after both having attended Ohio State University, so their chemistry was already more advanced than most rookie QB-WR combinations entering the league.

Expectations for the Redskins are low for their 20 season, as they commonly have been over the past five-plus seasons, but that element should play perfectly into the accelerated development of the Redskins on both sides of the ball, but specifically on offense with Derrius Guice.

The offensive line of the Redskins is a bit in shambles, as right guard Brandon Scherff and right tackle Morgan Moses look to be the only solid and incumbent OL starters that will be able to keep Haskins upright this year, which spells disaster. Derrius Guice cant feel comfortable about that situation.

With Haskins blindside currently being protected by projected starters Geron Christian Sr. at left tackle and Wes Schweitzer at left guard, as well as Chase Roullier at center, this offense may revolve around getting the ball out of Haskins hands early in the play and not relying on long-developing route trees and plays, which would help increase Guices involvement.

In his five games last year, Derrius Guice received nine targets, seven of which he caught that went for 79 yards and one of his three touchdowns, including a long of 45 yards. A 77.8 percent catch efficiency percentage is quite high for a running back, even if it is in a vacuum.

Derrius Guice has the hands to be a multi-faceted running back that can serve as a great compliment to what Peterson has provided this team so far, which is a power back that is starting wear down and cannot command 20+ touches each and every game because of needing to keep him fresh. And while Guice cannot be brought back necessarily in full capacity right away so he can try and build up his susceptibility to injuries, it would be in the teams best interest to move forward with him as their lead back from the jump.

Haskins is 24, Derrius Guice is 22, and McLaurin is 23, which is a prime age for this team to try and take advantage of up-and-coming players on their rookie deals. For the Redskins, their defense, which has been the constant focus of early draft picks lately, like Chase Young, Daron Payne, Jonathan Allen, and Montez Sweat, is at a pretty solid spot, especially with strong safety Landon Collins having come over from the divisional rival New York Giants, so the team is now for them to try and maximize their current roster on the offensive side of the ball.

The NFC East, or the NFC Least as it is so affectionately known as, continues to give 8-8 and 7-9 teams hope on a yearly basis to be able to either win the division or sneak into the postseason as the final Wild Card team while the Redskins still project as a sub-.500 franchise for this upcoming season, their chances at progressing up the standings in the division rest very heavily on the health of Derrius Guice, albeit not fully.

Ultimately, Derrius Guice will be looked at as the two-way player that he was drafted to be, even though it has taken much longer than expected to make that kind of impact. His abilities to give the run game another option that can help with outside runs, all while providing a solid screen game/dump-off/split-out option as a receiver will help give this offense another element and if he cannot, there are other options waiting in the wings to take his spot.

Washington will not be great this year again, as their first season under new head coach Ron Rivera will help dictate the future of this franchise and which direction they are heading. For Derrius Guice, while he is no Christian McCaffrey by any means, he can help fulfill that type of role for Rivera and his offense in a way; his role may actually resemble more of what DeAngelo Williams brought to the table for the Panthers. Peterson can have the role Jonathan Stewart owned as the bigger back who was used mainly for between the tackles.

Derrius Guice is the best running back on the roster based on ceiling and potential talent alone whether he realizes and reaches that remains to be seen, but his abilities to break out will dictate the kind of future success the Redskins offense has moving forward.

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Why Derrius Guice is the key to the future of the Redskins offense - ClutchPoints

Cheers to no fears!

A 104-year-old woman in the U.K. who recently recovered from the novel coronavirus has playfully credited her love of champagne to overcoming not only COVID-19, but surviving the Spanish flu and two world wars.

Jane Collins is back at The Gables care home where she resides in Derby, England after being hospitalized for the viral disease and reportedly recovering in just 10 days, news agency South West News Service (SWNS) reports.

Jane Collins, 104,recovered from the novel coronavirus has playfully credited her love of champagne to her incredible longevity. (SWNS)

GLOBAL CHAMPAGNE SALES FIZZLE AMID CORONAVIRUS PANDEMIC BECAUSE PEOPLE AREN'T CELEBRATING

According to the outlet, Collins said shes doing very well and feeling stronger each day.

Im still tired but Im enjoying the cake and a little bit of champagne, the centenarian said.

Her great niece Sarah Balmforth also echoed that the golden bubbly is Collins secret to longevity.

Her great niece Sarah Balmforth also echoed that the golden bubbly is Collins secret to longevity. (iStock)

Balmforth, 53, works as a nurse and said the family was terrified when Collins was diagnosed with the coronavirus in late April.

When she was admitted to hospital, we were told to expect the worst due to her age and frailty, the niece said. She went into hospital with extreme lethargy and 24 hours later it was confirmed she had coronavirus. She was given superb care and she got stronger and stronger each day.

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It was worrying because you wonder if a 104-year-old still has enough in her to survive, but she absolutely did, Balmforth continued. She had an iron constitution and she was strong willed. She loved red wine and a glass of champagne thats her secret.

Collins worked in the health care industry for many years, and in a twist of fate, was once even employed at the Royal Derby Hospital where she fought COVID-19, SWNS reports.

The fiercely independent woman has been widowed for about 50 years and continued driving until she was 101. Collins even lived alone until she was 102, before moving into The Gables.

Im still tired but Im enjoying the cake and a little bit of champagne, the centenarian said of her recovery from COVID-19. (SWNS)

According to her Balmforth, who affectionately calls her great aunt a second mum, Collins loved ones are not surprised that she has recovered from the coronavirus after surviving the Spanish flu and two world wars in the 20th century.

CLICK HERE FOR FOX NEWS' CONTINUING CORONAVIRUS COVERAGE

Shes always been a strong willed woman. Shes a source of pride for me, shes as sharp as shes ever been and still has her wits about her, the proud niece said. Its not surprising at all that she has survived everything that she has, I think itll take quite a bit more.

Jane was always a character. She used to tell me shed wait for everyone to get into church so she could make an entrance, Balmforth joked. And even today, her nails and hair are always immaculate.

Excerpt from:
Coronavirus survivor, 104, jokes that champagne is her secret to longevity - Fox News

The COVID-19 pandemic will change the global business landscape to its core. Investors are switching their attention from what was previously considered important sectors such as real estate, tourism and hospitality to what is truly important: human health.

The pandemic clearly will provide a tremendous boost to the biotech and bio-medicine industries, with a particular emphasis on preventive medicine.Recently, for example, two venture-funded rounds of more than $1 billion each (Arch Venture Partners and Qiming Venture Partners) were finalized. Meanwhile, several biotech companies closed sizeable funding rounds (e.g., Mabwell biotechs recent $278.5 million Series A injection, iTeos Therapeutics recent $125 million Series B2 financing, Affinivax's recent $120 million Series B round, among others).

Accordingly, expect to see a dramatic rise in the volume of investments going to healthcare in general, and preventive medicine in particular, including diagnostic and prognostic technologies. Money will also be earmarked for the detection and neutralization of diseases in advance of their pathological progression. All of this funding has one major goal: to strengthen the performance of the human immune system.

Promoting a healthy life in all its forms: physical; psychological and financial

Our frontier technology-focused consortium, Deep Knowledge Group, understands the scale and scope of the progressive healthcare and longevity industry, and of what longevity actually means in practice. Specifically, instead of focusing exclusively on what can be considered as core geroscience (R&D-stage therapies focused on treating the hallmarks, or root causes, of biological aging), our framework includes other relevant sectors, ranging from the biomedical to the technological and financial. In our view, the longevity industry encompasses anything promoting a healthy life in all its forms: physical; psychological and financial.

Read: Why virus stocks are driving market volatility

From a biomedical perspective, one of the biggest factors is optimizing the performance of the human immune system. You cannot live long if you are not properly protected from pandemic threats. For example, supercentenarians people who have lived at least 110 years possess certain features fostering a strengthened immune system, thus neutralizing diseases early in their lives and enabling greater protection from microbes, bacteria and viruses.

To advance such understanding, we expect investors to prioritize the sub-sectors with the greatest potential for disruptive impact: digital health; biomarkers of longevity, and in particular, artificial intelligence for healthcare, drug discovery, preventive medicine, and longevity, which is a major priority for our longevity-focused investment fund, Longevity.Capital.

Enhanced immunity is one of the most fundamental ways to improve health outcomes in the elderly, the group most at risk for infection, pathology and death during pandemics. Anti-pandemic (immune system optimizing) strategies and approaches for maximizing healthy longevity go hand-in-hand another reason why the current pandemic will lead to a rise in longevity-focused investment.

COVID-19 will reshape biotech, preventive medicine, precision health and longevity efforts in substantial and largely positive ways. One of the secondary goals behind the creation of Deep Knowledge Groups new COVID-19 MedTech Analytics IT-Platform was exactly this obtaining a deeper and more tangible understanding of how trends in biotech investment and industry development generally will change and adapt in the wake of the current COVID pandemic.

This platform is designed to serve as a comprehensive database of the most relevant entities, technologies, and developments in the COVID-19 MedTech ecosystem aggregating, profiling and visualizing the companies, organizations, scientists and technologies at the forefront of neutralizing the COVID-19 pandemic and ensuring the health and safety of individuals and nations. The platform aims to cover all major sectors and relevant activities in the global COVID-19 MedTech landscape, from science to technology, R&D, treatment, diagnostic and vaccine development, and practical applications occurring globally, providing data on particular scientific and technological sectors and geographical regions.

The COVID-19 pandemic will bring significant investments and developments to the biotech and bio-medicine industries, as well as a shift from treatment and healthcare (which can in practice be viewed as sick care) towards early-stage prevention, diagnosis, and tangible, data science-driven enhancement of the immune system and extension of the healthy period of life. This trend in turn will lead to an increase in global financial growth and stability by reducing the economic burden of age-related diseases, and by neutralizing the significant risks an aging population poses to the health, stability and vitality of national economies.

Our previous assessment of the longevity industrys growth predicted a market value of $27 trillion by 2026. Yet considering the impact that COVID-19 is making on biotech investments, we see this figure as being much larger. COVID-19 will grow the rate and size of biotech investments generally, and investments in preventive medicine, precision health and healthy longevity in particular.

Health is the new wealth. The pandemic is causing many people to realize what is truly important in life, and to view their personal health and longevity as the most valuable asset class of all.

Dmitry Kaminskiy is founder of Deep Knowledge Group and founding partner of Longevity.Capital. He is co-author of Longevity Industry 1.0: Defining the Biggest and Most Complex Industry in Human History

Kate Batz is managing partner of Longevity.Capital and director of strategy and business development at Deep Knowledge Ventures.

More: Everything you need to know about the Oxford University vaccine and other efforts to beat coronavirus

Plus: Good news for older Americans: 70 is the new 60 (but not for everyone)

Continue reading here:
Biotechs smart money is already focused on disease prevention, boosting immune systems and longevity - MarketWatch

On the West Coast of the United States, the coastal redwoods in Northern California can live more than 2,000 years. Giant sequoias in central California routinely reach over 3,000 years in age. The oldest living organism in the world old Methuselah, a bristlecone pine tree has survived for over 4,700 years.

Millenia-old trees have held their place on Earth long and steady, and scientists have been curious about how theyre able to survive for so long. Native to China, the Ginkgo biloba can also survive over 1,000 years. By studying these long-living trees, a team of collaborating scientists between China and the United States identified specific genes that explain how the trees stay virtually immortal and thriving. They published their results in the Proceedings of the National Academy of Sciences.

Ginkgo trees are biologically unique. Fossils resembling their elegant fan-shaped leaves date back over 200 million years. Paleobotanists have concluded the modern ginkgo tree has barely changed throughout their long history. The tree's closest relatives have all died out: Ginkgos are evolutionarily isolated, [so theyre] the single surviving species of a lineage that completely died out, explains Judy Jernstedt, a plant anatomist who studies ginkgo shoot architecture at the University of California, Davis and was not involved in the study.

But out of these distinct qualities, their most intriguing trait remains their longevity.

We went to a very local area in Hubei Province, explains Jinxing Lin, a plant biologist at Beijing Forestry University and a senior author of the study. To try to understand the biological reasons for how the trees could live for so long, the researchers wanted to compare genetic samples between young and old trees to bring back to their lab. However, they had to first determine the trees ages and find fitting samples to analyze.

Leaves, you know, can fall down every year and could not reflect the real age. So, we used the old vascular cambium, Lin said.

The vascular cambium is a ring of cells that form a layer underneath the bark. Theyre cells without specialized roles that will continuously divide and grow, either inwards towards the trunk as wood or outwards as bark. Even centuries-old ginkgo trees, can still divide several cells each year from the cambium, added Lin.

As a tree grows, the vascular cambium increases the girth of the trunk. Seasonal changes and growth patterns mean that this growth will produce about one additional ring in the trunks patterning every year.

Youve got to go in there and use a bore to go right into the center of tree and then pull it out, explains Richard Dixon, a biologist at University of North Texas and a senior author of the study, and then youve got to do the aging of the tree based on the rings.

With this method, the researchers collected samples from 34 ginkgo trees between 15- and 667-years old. They compared the ginkgo trees RNA in the vascular cambium to observe how their genetic activity changed between different age points.

In the 600-year old trees, genes associated with defenses against pathogens and disease resistance remained steadily active. The activity of other genes related to producing antioxidants, antimicrobials, and stress-response signals also didn't seem to be declining either. In other words, the older ginkgo trees appeared just as hardy as the younger trees. We really couldnt tell the profile for a 600-year old tree from a 20-year old tree, marvels Dixon.

Gene activity related to senescence the stage of life where cells lose their ability to divide and the tree begins to deteriorate and die also stayed consistent in the older trees, showing no signs of increasing with age. We thought after several hundred years they should go into senescence, recalls Lin. But genetically, the old ginkgo trees appeared as youthful as ever. We found the trees can still produce very good seeds and pollen, and theyre still in a healthy state.

These results are some of the first pieces of evidence pointing scientists towards the molecular underpinnings of aging, or a lack of it, in trees. Although the oldest trees in the study were about 600 years old, Dixon believes even older ginkgo trees estimated to be over 1,000 years old would show similar patterns of health and youth.

Bristlecone pine, redwood, sequioa, and gingko trees can all live for thousands of years

Photo by Juvian Duff on Unsplash

Similar genetic mechanisms could possibly be responsible for longevity in other long-living trees as well. Maybe people will now be doing these kinds of experiments in redwoods or in...yew trees or bristlecone pine trees, says Dixon.

To add to the ginkgo's list of quirks, the species is also notoriously hardy. Theyre unusually resistant to diseases, pests, and pollution, making them popular for city planners in urban settings. Famously, a small stand of ginkgo trees survived the nuclear blast from the atomic bombing of Hiroshima, and even flowered the next spring.

This biological phenomenon shapes new questions for Dixon and Lin. They say the next planned step for their research group is to study the somatic mutation rate of ginkgo trees. Somatic mutations are changes in DNA that are not inherited from sperm or egg cells, but rather acquired later on from environmental factors such as ultraviolet light or radiation. What protects the integrity of the ginkgo genome so well? For the genetic profile of a mature ginkgo tree to closely resemble a young one, does that mean somatic mutations are slower to accumulate?

Or, does something that lives a thousand years have to have a better DNA repair mechanism? Dixon wonders, If it did, that would be phenomenal, I think.

View original post here:
The genes of 600-year-old gingko trees are just as active as their teenage counterparts - Massive Science

The naked mole rat never develops age-related diseases. It stays active and enjoys good bone health, reproductive success and mental acuity for its lifespan of up to 30 years.

Two of many reasons for this creatures healthy longevity are its low body temperature and slow metabolic rate.

For the first time, researchers from the Institute of Gerontology in Kiev and Prof. Vadim Fraifelds Lab for the Biology of Aging at Ben-Gurion University of the Negev in Israel have replicated those conditions in lab mice. A naked mole rat generally lives about eight times longer than a mouse despite its similar size.

The research results, published in Biogerontology, have intriguing implications for increasing longevity and decreasing major pathologies in humans as well.

According to the scientists, the naked mole rats burrows are poorly ventilated, keeping oxygen levels are low and carbon dioxide levels high. This may cause the reduction in the naked mole rats body temperature by 3-4 degrees as compared to mice and slow its metabolism significantly.

A naked mole rat in its burrow. Photo by Neil Bromhall via Shutterstock.com

Subjecting laboratory mice to the same conditions called a hypoxic-hypercapnic environment (HHE) successfully reduced their body temperature and metabolic intensity for weeks and even months.

And the mice in the HHE voluntarily consumed less food, which is one of the well-known factors in increased longevity.

Unexpectedly, the HHE accelerated skin wound healing, despite the lower energy expenditure, the researchers also noted.

All in all, a chronic exposure to HHE offers a potential of being a lifespan-extending intervention as well as an efficient tool for treating the overweight and associated metabolic disorders.

The scientists explain that at one point in history, the Earth contained much lower levels of oxygen and higher levels of carbon dioxide.

There is still some memory in our cells of that period and therefore it should be possible in the future to induce such a state for longer periods, they said.

Moreover, they believe that HHE conditions could be used to help fight obesity, diabetes and perhaps even cancer.

Secrets of long life

The naked mole rat (Heterocephalus glaber), a rodent native to East Africa, has long been the subject of study because of its unusual healthy longevity and particularly its resistance to cancer.

In 2012, Tel Aviv University evolutionary biologist Dorothee Huchon and colleagues at the Texas Health Science Center and the City College of New York determined another reason for the naked mole rats unusual life expectancy: very high levels of a neuro-protective protein called Neuregulin 1 (NRG-1) in its brain.

Because NRG-1 is also found in the human brain, Huchon and her fellow researchers suggested that learning more about how aging and NRG-1 are related could be significant.

Fraifeld studies many aspects of human aging genomics. Graduate students in his Lab for the Biology of Aging at BGU won an award for their study on longevity genes, genetic protective factors that some people are lucky enough to inherit.

By modulating the activity of these genes in advanced age, it could be possible to combat major diseases.

Although an apparent paradox, it appears that the most effective way to delay or even to avert age-related diseases is to live longer, Fraifeld told ISRAEL21c.

Another prominent Israeli longevity researcher, Bar-Ilan Universitys Haim Cohen, recently published a study showing that SIRT6, considered a longevity-related protein, is involved in regulating biological processes including aging, obesity, insulin resistance, inflammation and metabolism. His team hopes to identify therapeutic approaches that target and activate SIRT6.

Ben-Gurion University researcher Debbie Toiber specializes in studying SIRT6 and DNA repair as models of age-related diseases.

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Researchers can extend the lifespan of mice: Are WE next? - ISRAEL21c

As coronavirus-induced mortality rates feature persistently in the nightly news, life feels more fleeting and fragile than before. Yet Israeli and Azerbaijani researchers are among those investigating the secrets behind longevity.High in the mountain forests of Eurasias Caucasus region and down in the leafy lowlands of Azerbaijan, clusters of superagers generally those age 90 and above have inspired generations of documentarians and scientists alike to plumb the mysteries of living a long life.Storytellers long have circulated tales of groups of Azerbaijanis living to be more than 120; a museum in the city of Lankaran honors the countrys long livers. Since the 1970s, Azerbaijans overall life expectancy has settled into the global-average range of 71. Still, an unusual number of Azerbaijanis, primarily in remote areas, have overwhelmingly defied the average.What exactly affords Azerbaijans superagers the ability to keep on living?ClustersWhy have clusters of superagers not just isolated superagers appeared in Azerbaijan and elsewhere in the world? Genes and family history come into play. Looking at the clusters in Azerbaijan may add to the body of knowledge of medical factors and family patterns that proactively contribute to longevity.A growing number of scientists consider aging to be a preventable condition that can be addressed by gene therapy. Such an approach contrasts with the medical communitys traditional focus on the risk factors that pose impediments to long life. Lessons to be learned from Azerbaijan and elsewhere may contribute to our ability to prolong life.GeneticsThe New York-based Albert Einstein College of Medicines Dr. Nir Barzilai, an eminent leader in longevity research, has not personally examined the Azerbaijani case but points to his long-term research on Ashkenazi Jews in discussing the issue of clusters.Israeli-born Barzilai, founding director of the colleges Institute for Aging Studies and scientific director of the American Federation for Aging Research, has identified or corroborated longevity-associated gene markers that include the cholesteryl ester transfer protein gene (CETP). In one form, CETP correlates with slower memory decline, lower dementia risk, and significant protection against heart disease. CETPs appearance is affiliated with higher good cholesterol (HDL). Scientists and pharmaceutical companies such as Merck have looked to CETP and other identifying markers as means to interrupt age-related diseases.Barzilais study of the largely homogeneous Ashkenazi Jewish population has revealed shared genetic elements resulting in patterns. The research has helped Barzilai and others develop mitochondria-based therapeutics for diseases associated with aging.LifestyleLifestyle matters, scientists and laypeople generally agree. Whether it be taking daily walks or turning off the news, people who live a life focused (but not overly focused) on healthy habits tend to live longer.Dr. Anatoly Khaimovich Rafailov, a surgeon with more than 40 years of experience who leads the Azerbaijan-Israel Inter-Parliamentary Work Group in the Azerbaijani Parliament, attributes the high life expectancy in some regions of Azerbaijan to two factors. First: the residents of those regions widely use Berberis (Barberry) in their everyday meal. The anti-oxidant, anti-inflammatory, and other healing properties of Berberis are well-known since ancient times, he says. The second factor is that people there are very active physically daily, they walk about 18-20 kilometers (11-12 miles). And motion is life.Many Azerbaijanis cite a diet centered on unprocessed, organic foods and a lack of involvement in harried debate as keys to long life. Dr. Tahir Amiraslanov, president of the Azerbaijan National Culinary Association and editor-in-chief of the Kulina scientific journal, says, People eat what they grow, use clean water and fresh air, live in a house with a large, multigenerational family, and overall live a natural life and try to do good things.Professor Ulduz Hashimova, director of the Institute of Physiology at the Azerbaijan National Academy of Sciences in the countrys capital of Baku, shares that her institute has made understanding superaging an institutional priority for several years. The institutes comprehensive research has spanned disciplines, from genealogy to ecology, neurology, biochemistry, and beyond. Most published works deriving from this effort are written in Russian, which may partially explain the Wests general lack of familiarity with this research.From the pandemic to the futureAzerbaijan has fostered significant partnerships in the humanities and other disciplines, and the West is building an understanding of Azerbaijani culture and contributions. Amid the pandemic and in the coming years, the US scientific community may look to Israel and Azerbaijan who are partners in technical and other arenas for breakthroughs in the understanding of aging.The Azerbaijani superaging phenomenon may also be of particular interest to social scientists, given major societal changes during the past century. Consider this: Someone over the age of 100 might have witnessed what is now the Republic of Azerbaijan as a portion of the Russian Empire, a part of the early Azerbaijani Democratic Republic, and as an S.S.R. of the Soviet Union.As societies become increasingly heterogeneous, we can learn from families and communities with shared characteristics. We may unlock more life-extending therapies. Meanwhile, as research progresses, we can make the lifestyle changes already identified as keys to longevity.Diana Cohen Altman, principal of Cultural Diplomacy Associates, L.L.C., and former executive director of the US cultural non-profit Karabakh Foundation, writes extensively about Azerbaijani cultural and civil-society topics.

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Do Azerbaijan and Israel possess the secrets of a long life? - The Jerusalem Post

Beating coronavirus, especially when youre older and considered high-risk, is worthy of a celebration.

Some COVID-19 survivors are also 100-years-old and older, which means theyve also lived through and survived their fair share of pandemics, like the Spanish Flu, World Wars, and the Great Depression.

The New York Post reached out to the survivors to get one answer -- whats the secret to longevity?

Walter Reed of East Rockaway, LI said he believes that in order to have a long life, you need a good diet. I never smoked. I watched my diet, he said.

Reed also maintained a positive outlook on life: I always try to do the right things: You never hear me cussing I dont get angry, I hold my temper down. I walk away and have a good relationship with everybody.

A positive attitude and resilience is credited with helping 104-year-old Ida Acconciamessa, who, in addition to overcoming COVID, also survived stage 4 melanoma, the Spanish Flu, and recovered from two broken hips.

Meanwhile, 101-year-old Rose Leigh-Manuell of West Sayville, LI, credits her faith with getting her through the hard times.

God takes good care of me, the devout Protestant told the publication.

She had such an upbeat attitude about everything. One of her favorite sayings when things go bad: This too shall pass, her son, Gary said.

The grandmother of eight, who loves to snack on Oreos, also notes its important to spend time with your loved ones and prioritizes weekly dinners with her son.

Gary said his mother seemed young despite her age: she worked in a fish market up until she was 95, so that would have been six years ago. And the only reason she stopped working is the fish market closed.

Having something to look forward to and a family to come home to is equally as important.

WWII veteran Vincent Simeone, 99, made sure nothing got in the way of attending his granddaughters wedding, not even COVID.

"It was a huge surprise and it was great to see him standing and waving, smiling," his granddaughter Amy Zimmerman Scudieri of his attendance.

Some are just born with it, according to 104-year-old Lilian Menendez who believes her longevity is due to her strong genes.

My mother was 98 and she didnt have a gray hair in her head she was jet black, Mendez recalls.

Staying active is key, says Dave Stejna, the grandson of 103-year-old Jennie Stejna.

Shes the most high-energy person I ever met, he said adding, Into her 90s, I would go places with her and I could barely keep up.

Stejna manages to refuel with a cold beer, which Dave says shed often indulge in on a hot summer day.

Its no coincidence that when she celebrated her recent recovery from coronavirus by enjoying an ice cold Bud Light!

We'll cheers to that!

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100-Year-Old Coronavirus Survivors Reveal the Secrets to a Long and Healthy Life - WWJ Newsradio 950