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Archive for the ‘Longevity’ Category

Serena Williams Reveals Secret To Longevity, Gives Venus Williams Advice – International Business Times

Sunday, December 15th, 2019

KEY POINTS

Serena Williams revealed how she managed to keep her winning ways and gave her sister Venus a piece of advice.

In her stellar career, Williams has ultimately become one of the greatest tennis players of all time. However, the five-time WTA Tour winner doesnt really believe she is womens Tennis GOAT.

In a recent interview with Tennis World USA, Williams said that she never thought that her name will be included in GOAT talks. In fact, even to this day, Williams doesnt think about it too much.

When my career started I never thought that I would be even in the conversation of the greatest. Now I don't think of a number too much. Obviously I would like if get to a certain number, but I don't think about it too much because I don't want to be. I just want to enjoy every moment that I have, Williams said.

Williams then revealed her simple secret to longevity. According to legendary tennis player, she doesnt put the pressure of winning more Grand Slams on herself and just want to enjoy every moment.

You know, every time I win Grand Slams, if I continue and I will try my best to win more I just want to have fun with it, so... I think what enables me to win more is the fact that I don't put that pressure on myself, Williams revealed.

The Olympic gold medalist also spoke about her sister Venus, who, despite dealing with Sjogren syndrome, has kept competing at the highest level.

According to Serena, if she werein Venus shoes, she would have opted to play doubles.

If I were Venus, I probably would have been like, Well, I might just play doubles, Serena said.

But Serena admires her sisters eagerness to still compete despite the fact that Venus might never be the same player she once was.

But her spirit and her, like, it's just amazing because I know what she goes through more than anyone else here, and sometimes she's doing great and sometimes it's different and it's difficult. She might lose matches that she would normally win 10 times out of 10, but to accept that and keep going is really amazing, Serena of her sister Venus.

Serena Williams hugs Venus Williams after her loss to her sister during Day 8 of BNP Paribas Open on March 12, 2018, in Indian Wells, California. Photo: Kevork Djansezian/Getty Images

Just recently, Serena posted a touching message about Venus on social media. Serena wrote the caption next to an Instagram photo of Venus standing on a beach showering the older Williams some sisterly love.

Doubles partner sister soulmate one of my fav sisters@venuswilliams, Serena wrote.

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Learn the importance of having an income distribution plan – Press of Atlantic City

Sunday, December 15th, 2019

By now, most people know they should have a financial plan, even though many do not. But what about an income distribution plan? For decades, the benefits of financial plans have been discussed but only for the last few years have we begun to hear about income plans. The reason for the recent discussion is due to our aging population. According to a 2017 AARP study, 10,000 baby boomers are turning 65 every day, and this is expected to continue into the 2030s!

Investors have been taught well how to save and invest for their retirements, but they havent had nearly enough education on how to spend what they have taken most of their lives to accumulate.

Spending down your assets is one of the biggest issues facing retirees today. To be honest, saving for retirement isnt all that hard. By buying a well-diversified, low-cost, mostly equity portfolio, the market is going to do most of the work. Where the real challenge lies is in unsaving or spending down these same assets in retirement. But how do we go about doing that? You have to be aware of things like income and capital gains taxes and their effects on your returns as well as on your spendable income. As the old saying goes, its not what you earn, its what you take home. What about the make-up of your portfolio? Become more conservative is an all too familiar mantra of advisors. But what does that mean? Does it mean having fewer equities? More bonds? What risk are investors avoiding, and more importantly, what risk is it creating for them? In particular, longevity risk the risk of outliving your savings!

In a traditional portfolio, retiring at the wrong time, which can impact sequence of return risk, can have a disastrous effect on whether or not you have enough money to maintain your standard of living in retirement. Losing money in the first few years of retirement, combined with retirees tending to living longer, or longevity risk, can create a perfect storm for those nearing or in retirement. You must have a plan to mitigate that risk.

By having a formal income distribution plan in place, retirees can address the primary issues surrounding them today such as:

1. What assets to spend in which order

2. Integrating Social Security claiming strategies into an income plan

3. Risk control in a portfolio, including longevity, sequence of return and volatility

4. Low interest rates

5. Taxes

Having a formal income distribution plan in place can potentially help retirees have a more enjoyable retirement.

T. Eric Reich, CIMA, CFP, CLU, ChFC is president and founder of Reich Asset Management and can be reached at 609-486-5073 or eric@reichassetmanagement.com.

Securities offered through Kestra Investment Services, LLC (Kestra IS), member FINRA/SIPC. Investment advisory services offered through Kestra Advisory Services, LLC (Kestra AS), an affiliate of Kestra IS. Reich Asset Management, LLC is not affiliated with Kestra IS or Kestra AS. The opinions expressed in this commentary are those of the author and may not necessarily reflect those held by Kestra Investment Services, LLC or Kestra Advisory Services, LLC. This is for general information only and is not intended to provide specific investment advice or recommendations for any individual. It is suggested that you consult your financial professional, attorney, or tax advisor with regard to your individual situation.

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How to live a long, productive life, according to a 102-year-old who just released his first album – CNBC

Sunday, December 15th, 2019

"I know I'm mad about you, and all but lost without you, and great affection for you I proclaim.... But baby, there's an issue I just can't remember your name."

So goes the chorus of "I Just Can't Remember Your Name," on the 10-track album, "Senior Song Book" released in November. The lyrics are a humorous nod to a common pain point about aging. After all, the song's writer, Alan R. Tripp, is 102.

What's more, it's Tripp's first album.

"People ask me how did I live so long and have my mind clicking away," he told NPR's "All Things Considered." "The answer is you do not retire from something. You retire to something," said Tripp. "And your life will continue with any luck."

That's exactly what Tripp who has had multiple careers, including as a radio news broadcaster, an advertising executive and a businessman has been doing. Though, for the record, he considers himself "semi-retired," according to a promotional interview he did with his publicist.

Still, Tripp's lastest foray into music production wasn't entirely planned.

When Tripp was 99, he wrote a poem called "Best Old Friends" about the new friendships he had made at Beaumont at Bryn Mawr, the Pennsylvania retirement community where he lives. Marvin Weisbord, 88, who lives at Beaumont too, turned the poem into a song for Tripp's 100th birthday.

That song catalyzed the album. Weisbord plays piano on the album, and the two produced it at a local recording studio.

Marvin Weisbord (L) set a poem his friend, Alan Tripp, wrote to music for Tripp's 100th birthday. That catalyzed the album.

Photo courtesy Lisa Schaeffer Photography

Now that the CD has dropped (and is on back-order at CDBaby as of Friday), the centenarian is planning his next move.

"I was writing a book when this thing came up," Tripp told NPR. So that will be his next endeavor.

"It's a mystery book. I've written several other books, but never a mystery. So when I'm done with this, back to the computer and write that mystery book," Tripp told NPR. (Tripp published one book in 1992, one in 2006 and a third in 2015.)

Japanese longevity expert, Dr. Shigeaki Hinohara, who lived to be 105, also said the key to a long, happy life was to stay active.

"There is no need to ever retire, but if one must, it should be a lot later than 65," Hinohara told The Japan Times in 2009.

From the age of 65, Hinohara worked 18-hour days, seven days a week as a volunteer and "love[d] every minute of it," he said. In fact, he volunteered until the last few months before his death on July 18, 2017, according to The New York Times.

Fashion icon, Iris Apfel, 98, is also still working. She released the book "Accidental Icon" in 2018 and still juggles any number of fashion collaborations, including a line with The Home Shopping Network.

"For me, retirement is a fate worse than death," she told Money in 2018 after her book release. "I've seen so many people, especially in a place like Palm Beach, who worked so hard in their lives, and they come down here cold turkey, and then one day wake up and they realize how vacuous their lives are now. I mean it isn't funny, I've seen it with my own eyes!"

Tripp seems to agree: "If you retire to slothfulness, believe me you'll be a slob," he said in a promotional interview he did with his publicist. "That's all that will happen to you."

See also:

This Japanese longevity expert lived to 105 here's what he ate every day

95-year-old fashion icon Iris Apfel says hard work is her fountain of youth

Iris Apfel: 10 life lessons from a 96-year-old who is probably cooler than you

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Study with centenarians finds novel protein signature of protective APOE genotype – National Institute on Aging

Sunday, December 15th, 2019

A novel protein signature may have the potential to serve as a biomarker for resistance to Alzheimers disease and cognitive decline, according to a new study with a group of centenarians and their offspring. The researchers found a correlation between 16 proteins found in blood and the 2 form of the apolipoprotein E (APOE) gene. The study, led by investigators at Boston University in collaboration with the NIA Intramural Research Program and Novartis, was reported in Aging Cell.

Having the 2 form of the APOE gene is thought to be neuroprotective, whereas having the 4 form is associated with increased risk of late-onset Alzheimers disease and poor cognitive function. The 2 form, which is much rarer than 4, is more commonly detected among those over 100 years old and their children than in the general population. APOE 2 also seems to promote longevity, but the precise biological mechanisms for it being neuroprotective and promoting long life are not known.

Because recent studies showed that APOE-associated protein products can be found in blood serum samples, the researchers analyzed serum to find the biological products of APOE 2. Serum was collected from 222 people in the NIA-supported New England Centenarian Study, including 51 with APOE 2.

Using a protein profiling platform to analyze several thousand proteins in serum that corresponded to more than 4,000 genes, the researchers found that 16 proteins were associated with different APOE genotypes. They explored the different gene expression profiles of 16 proteins in brains of people with late-onset Alzheimer's disease and healthy controls and showed that the signatures were significantly different between the two groups.

Next, they confirmed their findings by repeating the analysis with serum and plasma samples from other cohort studies. Finally, they examined the association between the 16 proteins and changes in cognitive function in the centenarians and found that seven of these proteins correlate with patterns of cognitive function.

If future studies show that the signature proteins are driving cognitive health, rather than merely being associated with it, these proteins could serve as biomarkers in intervention studies targeting APOE 2. In addition, the protein signature identified in this study could be developed into an early detection test of resistance to developing Alzheimers.

This research was supported in part by the NIA Intramural Research Program; NIA grants U19AG023122, R21AG056630 and R01AG061844; and NIH contracts 263 MD 9164 and 263 MD 821336.

Reference: Sebastiani P, et al. A serum protein signature of APOE genotypes in centenarians. Aging Cell. 2019;18(6):e13023. doi: 10.1111/acel.13023.

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Mahesh Bhatt: More interested in the longevity of my films than by their debut grosses – Hindustan Times

Wednesday, December 11th, 2019

Filmmaker Mahesh Bhatt says he is more interested in the longevity of his films than by their debut grosses. Mahesh on Wednesday took to Twitter, where he shared a poster of his film Zakhm, which was released 21 years.

He wrote: I am more interested in the longevity of my films than by their debut grosses. I ask does it have anything to say in 10 years or 20 years? Could it still have legs? Could it still be around? History is rife with films that we love today that were bombs on their opening weekend.

Zakhm is considered of Bhatts finest directorial efforts and is said to bear autobiographical shades. The film won Ajay Devgn a National Award as Best actor, and also featured Pooja Bhatt, Sonali Bendre, Nagarjuna, and Kunal Kemmu as a child artist. The film won the Nargis Dutt Award for Best Feature Film on National Integration.

Also read: Deepika Padukones Chhapaak trailer earns praise from acid attack survivor Rangoli Chandel

Alia Bhatt accompanied by her father Mahesh Bhatt, addresses at the launch of her sister Shaheen Bhatt's book I've Never Been (un)Happier.(IANS)

Bhatt on Wednesday announced that he is venturing into the digital space with a web-series based on the relationship of a struggling filmmaker and a top female actor in the 70s.

Follow @htshowbiz for more

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Study Reveals How Planning For The Future May Help With Longevity – mindbodygreen.com

Wednesday, December 11th, 2019

Being a planner can set you up for success in every phase of life. For example, students who set goals are more likely to see improvements in academic performance, and older people aiming to adopt healthier lifestyles can reduce the effects of dementia. According to a new study, planning for the futureeven in the face of terminal illnesscan prolong life for up to one year.

The study, published in the journal BMJ Supportive & Palliative Care, found that patients who are terminally ill might live longer if they discuss advance care options with doctors.

Planning for advance care is a process between patients and health professionals, in which possible treatments, priorities, and desires for impending care are discussed. This is especially useful for doctors who have to choose whether or not to continue treatment when patients lose the ability to communicate.

In this particular study, researchers looked at the death dates of 205 patients with terminal illnesses, including advanced cancers, as well as heart and lung diseases. Of the patients, 102 had disclosed their advance care preferences while 103 did not.

Of the group who engaged in these conversations, 90% with lung and heart diseases lived beyond the next year. This was compared to 67% who did not talk to their doctors about the future. The outcomes of patients with cancer were not affected.

Until now, the connection between advance care discussions and longevity were unexplored. This research can provide hope for people who are diagnosed with progressive, terminal diseases and their families, who might get more time with loved ones.

The analysis was explorative, and more research needs to be done to find conclusive evidence, but researchers did suggest a possible reason for the increase in survival rates. "This type of conversation helps these patients better understand the life-limiting nature of their illness," a news release said. Recognizing the severity of these illnesses could make patients more willing to accept treatment.

The underlying message of these findings could be helpful for anyone, regardless of health. Finding a purpose has been known to improve mental and physical well-being, and that fact now holds true in the face of death.Perhaps discussing the future, in any capacity, can make it feel less out of reach.

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Reba McEntire Shares Her Secrets on Success, Longevity, and Staying Humble – Thrive Global

Tuesday, December 10th, 2019

Global star and widely loved country music artist, actress, and humanitarian Reba McEntire celebrates her 16th Grammy Award nomination this year for her album, Stronger Than The Truth, which has resonated deeply within the country music community. One of the greatest selling country artists of all time, McEntire has previously won the Grammy Award for Best Female Country Vocal Performance, Best Country Vocal Collaboration, and Best Roots Gospel Album, and she has also been nominated for a Golden Globe award and more.

We sat down with the reigning Queen of Country Music to talk her Best Country Album nomination, how she turned her passion into a hugely successful career that has spanned over four decades, and advice for other female artists. You can tune into the 62nd Grammy Awards on January 26, 2020.

Where were you when you received the news of your 16th Grammy Award nomination?

I was at home in Nashville and my phone started blowing up around 7:30 a.m., right as the nominations were announced. My entire team texted me to let me know the news! There were a lot of excited emojis!

How does this years Best Country Album nomination compare to the one you received in 1994 for Read My Mind?

Im incredibly proud of both albums. I still love music now just as much as I did then, and I still follow the same formula I did then pick great songs that touch my heart and hopefully theyll touch yours, too.

How does this nomination stand out amongst the other 15 you have previously received?

I wanted to go back to my roots on this album and make a stone-cold country album with great story songs. To be recognized for that some 30 years after my very first nomination is pretty special. Its just icing on the already really wonderful cake.

What about Stronger Than The Truth do you think resonated with the Recording Academy?

Its honest and authentic. Its full of songs that tell stories that I think anyone can relate to.

From your first nomination (and win) in 1986 to now, the 2020 Grammys, how has your outlook on awards and accolades changed?

Im still as competitive as Ive always been, but the pressure is less now. Of course I love to win awards, who doesnt? But now I take pride in knowing that Ive made the best album that I possibly could and that is my reward, whether I take home a trophy or not.

Many of the songs on your album have been on your radar for years. How does it feel to see these songs officially having their moment of recognition?

Im just thrilled to see great songs being recognized, and Im thankful for all the writers letting me be the conduit for their work.

How does it feel to have your music consistently recognized for over three decades?

Well it feels great! I, and my entire team, work very hard to put out music that means something and connects with the listener. Im beyond grateful to still have the platform that I do and I take it very seriously.

Thats why I do this I want the music and the songs to reach out and touch people and make them feel like theyre not alone and that someone else understands.

You most recently took home the award for Best Roots Gospel Album in 2017. How have you incorporated your faith into your country records, and what similarities do you see between the genres?

My faith is part of everything I do. I pray every day that the Lord will use me and guide me in my all my decisions. I may not be singing directly about God and Jesus, but that doesnt mean the ideas arent there. Songs like You Never Gave Up On Me on this record could be about someones relationship with the Lord. Theres always been an overlap between Christian and country, and I think there always will be.

Stronger Than The Truth is your 33rd studio album a tribute to your success and fame. What has allowed you to remain grounded? How do you not let the pressures of success change you?

My family and my friends keep me grounded. No ones going to let my head get too big and they bring me back down to Earth real quick if I get to floating off too far. My sister, Alice, gave me a toilet seat cover one time for Christmas that on the top said, The Twinkle! So Im still working on being that star.

What has been the most unexpected joy you have received from creating this album?

Hearing how the songs have touched peoples hearts. Ive had people tell me they couldnt listen to the entire album through at one time because it was just too emotional for them. Thats why I do this I want the music and the songs to reach out and touch people and make them feel like theyre not alone and that someone else understands.

What things have industry peers shared with you about how they feel about this album that have surprised you? Is there anything that you didnt expect?

Ive had people come to me in tears with how much the songs have impacted them. I was just trying to make a great country record, and if people cry, that means we have touched their hearts. Making that connection is sweet.

What do you think sets you and this album apart from the other nominees?

I think weve all made really great albums, but were all very different and in different stages of our careers. I think its really great to see such diversity represented in the category with all types of country music.

Are there any moments from your past Grammy experiences that stand out to you? If so, what are they?

Winning the Grammy for Sing It Now is something Ill never forget. I made that record as a way to heal my own heart, and to see it connect with so many other people and then be recognized in that way meant the world to me.

What does it mean to you to be nominated for Best Country Album this year?

I dont take it for granted. There are a lot of great artists making incredible music out there every day, and I feel very honored to have my work recognized as standing out among the crowd.

If you could share one piece of advice with female artists getting their start, what would it be?

Stay true to your gut instincts. Ive always felt that is Gods way of directing me. Stay with the type of music you want to be making and what type of artist you want to be. Stand your ground and make music that youre proud of. Everything else will work itself out. Work hard, show up on time, be prepared and have fun!

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Why AI Will Be the Best Tool for Extending Our Longevity – Singularity Hub

Tuesday, December 10th, 2019

Dmitry Kaminskiy speaks as though he were trying to unload everything he knows about the science and economics of longevityfrom senolytics research that seeks to stop aging cells from spewing inflammatory proteins and other molecules to the trillion-dollar life extension industry that he and his colleagues are trying to fosterin one sitting.

At the heart of the discussion with Singularity Hub is the idea that artificial intelligence will be the engine that drives breakthroughs in how we approach healthcare and healthy aginga concept with little traction even just five years ago.

At that time, it was considered too futuristic that artificial intelligence and data science might be more accurate compared to any hypothesis of human doctors, said Kaminskiy, co-founder and managing partner at Deep Knowledge Ventures, an investment firm that is betting big on AI and longevity.

How times have changed. Artificial intelligence in healthcare is attracting more investments and deals than just about any sector of the economy, according to data research firm CB Insights. In the most recent third quarter, AI healthcare startups raised nearly $1.6 billion, buoyed by a $550 million mega-round from London-based Babylon Health, which uses AI to collect data from patients, analyze the information, find comparable matches, then make recommendations.

Even without the big bump from Babylon Health, AI healthcare startups raised more than $1 billion last quarter, including two companies focused on longevity therapeutics: Juvenescence and Insilico Medicine.

The latter has risen to prominence for its novel use of reinforcement learning and general adversarial networks (GANs) to accelerate the drug discovery process. Insilico Medicine recently published a seminal paper that demonstrated how such an AI system could generate a drug candidate in just 46 days. Co-founder and CEO Alex Zhavoronkov said he believes there is no greater goal in healthcare todayor, really, any venturethan extending the healthy years of the human lifespan.

I dont think that there is anything more important than that, he told Singularity Hub, explaining that an unhealthy society is detrimental to a healthy economy. I think that its very, very important to extend healthy, productive lifespan just to fix the economy.

The surge of interest in longevity is coming at a time when life expectancy in the US is actually dropping, despite the fact that we spend more money on healthcare than any other nation.

A new paper in the Journal of the American Medical Association found that after six decades of gains, life expectancy for Americans has decreased since 2014, particularly among young and middle-aged adults. While some of the causes are societal, such as drug overdoses and suicide, others are health-related.

While average life expectancy in the US is 78, Kaminskiy noted that healthy life expectancy is about ten years less.

To Zhavoronkovs point about the economy (a topic of great interest to Kaminskiy as well), the US spent $1.1 trillion on chronic diseases in 2016, according to a report from the Milken Institute, with diabetes, cardiovascular conditions, and Alzheimers among the most costly expenses to the healthcare system. When the indirect costs of lost economic productivity are included, the total price tag of chronic diseases in the US is $3.7 trillion, nearly 20 percent of GDP.

So this is the major negative feedback on the national economy and creating a lot of negative social [and] financial issues, Kaminskiy said.

That has convinced Kaminskiy that an economy focused on extending healthy human lifespansincluding the financial instruments and institutions required to support a long-lived populationis the best way forward.

He has co-authored a book on the topic with Margaretta Colangelo, another managing partner at Deep Knowledge Ventures, which has launched a specialized investment fund, Longevity.Capital, focused on the longevity industry. Kaminskiy estimates that there are now about 20 such investment funds dedicated to funding life extension companies.

In November at the inaugural AI for Longevity Summit in London, he and his collaborators also introduced the Longevity AI Consortium, an academic-industry initiative at Kings College London. Eventually, the research center will include an AI Longevity Accelerator program to serve as a bridge between startups and UK investors.

Deep Knowledge Ventures has committed about 7 million ($9 million) over the next three years to the accelerator program, as well as establishing similar consortiums in other regions of the world, according to Franco Cortese, a partner at Longevity.Capital and director of the Aging Analytics Agency, which has produced a series of reports on longevity.

One of the most recent is an overview of Biomarkers for Longevity. A biomarker, in the case of longevity, is a measurable component of health that can indicate a disease state or a more general decline in health associated with aging. Examples range from something as simple as BMI as an indicator of obesity, which is associated with a number of chronic diseases, to sophisticated measurements of telomeres, the protective ends of chromosomes that shorten as we age.

While some researchers are working on moonshot therapies to reverse or slow agingwith a few even arguing we could expand human life on the order of centuriesKaminskiy said he believes understanding biomarkers of aging could make more radical interventions unnecessary.

In this vision of healthcare, people would be able to monitor their health 24-7, with sensors attuned to various biomarkers that could indicate the onset of everything from the flu to diabetes. AI would be instrumental in not just ingesting the billions of data points required to develop such a system, but also what therapies, treatments, or micro-doses of a drug or supplement would be required to maintain homeostasis.

Consider it like Tesla with many, many detectors, analyzing the behavior of the car in real time, and a cloud computing system monitoring those signals in real time with high frequency, Kaminskiy explained. So the same shall be applied for humans.

And only sophisticated algorithms, Kaminskiy argued, can make longevity healthcare work on a mass scale but at the individual level. Precision medicine becomes preventive medicine. Healthcare truly becomes a system to support health rather than a way to fight disease.

Image Credit: Photo byh heyerleinonUnsplash

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MYOS to Introduce its Longevity Business with its Physician Muscle Health Formula at the World Congress on Anti-Aging Medicine in Las Vegas December…

Tuesday, December 10th, 2019

Product Leverages Fortetropin's Impact on Increasing the Rate of Muscle Protein Synthesis to Increase Muscle Mass and Strength for Improved Longevity

CEDAR KNOLLS, N.J., Dec. 10, 2019 /PRNewswire/ --MYOS RENS Technology, Inc. ("MYOS" or "the Company") (NASDAQ: MYOS), an advanced nutrition company and the owner of Fortetropin, a proprietary bioactive composition made from fertilized egg yolk that helps build lean muscle, announced today that it will launch its longevity business with the introduction of its Physician Muscle Health Formula at the 27thWorld Congress on Anti-Aging Medicine (https://www.a4m.com/las-vegas-december-2019.html) in Las Vegas, Nevada from December 13-15, 2019; MYOS will be in Booth #2090. Considered the largest event in anti-aging medicine, the World Congress is expected to draw approximately 4,000 Medical Professionals and 300 Exhibitors from around the world.

Earlier this year, MYOS announced that in a clinical trial involving 60-75-year-old men and women, subjects who consumed Fortetropin on a daily basis experienced an increase of approximately 15% in the rate of muscle protein synthesis when compared with subjects who received a macronutrient-matched placebo. The results from this clinical trial will be presented by its principal investigator, William J. Evans, Ph.D., Adjunct Professor of Nutrition, University of California, Berkeley at the International Conference on Frailty & Sarcopenia Research on March 11, 2020 in Toulouse, France.

Encouraged by positive results from this clinical study and previous studies showing that Fortetropin increases muscle mass and strength, MYOS decided to formally launch its longevity business by introducing its branded product, Physician Muscle Health Formula. This product will be distributed through medical practices focused on anti-aging medicine across the United States. In addition, the Company will also debut a private labeling service. This service will enable physicians to develop their own Fortetropin-based nutrition products in consultation with the Company's scientists and engineers, leveraging our portfolio of scientific research and clinical trials. Members of MYOS' scientific and business development staff will be at the Company's booth (#2090) to meet with medical professionals and discuss opportunities for collaboration.

"Fortetropin has remarkable potential to improve human longevity and we are pleased to share our advancements on improving muscle health at the upcoming World Congress on Anti-Aging Medicine later this week," commented Joseph Mannello, CEO of MYOS. "Maintaining muscle mass and health plays a vital role in supporting an excellent quality of life as we get older and has been shown in numerous respected publications to be associated with improved longevity. Muscle plays a central role in movement, energy metabolism and bone health. The beauty of MYOS' approach to addressing muscle health is that our products are all-natural nutrition products that capitalize on a patented manufacturing process and are backed by a large body of preclinical and human clinical research," added Mr. Mannello.

About MYOS RENS Technology Inc. MYOS RENS Technology Inc. (MYOS), "The Muscle Company", is a Cedar Knolls, NJ-based advanced nutrition company that develops and markets products that improve muscle health and performance. MYOS is the owner of Fortetropin, a fertilized egg yolk-based product manufactured via a proprietary process to retain and optimize its biological activity. Fortetropin has been clinically shown to increase muscle size, lean body mass and reduce muscle atrophy. MYOS believes Fortetropin has the potential to redefine existing standards of physical health and wellness. For more information, please visit http://www.myosrens.com.

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About Fortetropin Fortetropin works in conjunction with your protein of choice to help your body utilize that protein more efficiently. Fortetropin is made through a patented process that maintains the vital nutrients of fertilized egg yolks to help build more lean muscle and decrease muscle loss. For more information, please visit http://www.myosrens.com.

Forward-Looking Statements Any statements in this release that are not historical facts are forward-looking statements. Actual results may differ materially from those projected or implied in any forward-looking statements. Such statements involve risks and uncertainties, including but not limited to those relating to product and customer demand, market acceptance of our products, the ability to create new products through research and development, the successful results of strategic initiatives, the success of our products, includingQurr, Yolked, MYOS Canine Muscle Formula, Physician Muscle Health Formulaand MYOS Enteral NutritionFormula, the success of our research and development, the results of the clinical evaluation ofFortetropinand its effects, the ability to enter into new partnership opportunities and the success of our existing partnerships, the ability to generate revenue and cash flow from sales of our products, the ability to increase our revenue and gross profit margins, the ability to achieve a sustainable, profitable business, the effect of economic conditions, the ability to protect our intellectual property rights, competition from other providers and products, the continued listing of our securities on the Nasdaq Stock Market, risks in product development, our ability to raise capital to fund continuing operations, and other factors discussed from time to time in our filings with the Securities and Exchange Commission. We undertake no obligation to update or revise any forward-looking statement for events or circumstances after the date on which such statement is made except as required by law.

Investor Relations: Porter LeVay & Rose Matthew Abenante, IRC, SVP Phone: 212-564-4700 Email: MYOS@plrinvest.com

(PRNewsfoto/MYOS RENS Technology)

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Federal Agencies, Nonprofits and Global Companies Connect with Tech Entrepreneurs, Investors at Innovation in Longevity Summit Convened in Nation’s…

Tuesday, December 10th, 2019

WASHINGTON, Dec. 5, 2019 /PRNewswire/ -- The Washington Innovation in Longevity Summit (WIN) happening here December 9-10 at the National Press Club and produced by Mary Furlong & Associates, is the only conference that brings together a highly curated audience focused on solutions, partnerships, best practices and trends driving the $7.6 trillion U.S. longevity economy. The event is unique in that it selects the top innovators in aging technology backed by leading longevity market investors to share insights, learn from and connect with the federal agencies, private companies,nonprofits and media as well as potential global partners seeking impactful and sustainable innovation to support longer lifespans worldwide.

"The longevity economy offers vast domestic and global potential for investors and entrepreneurs but there are challenges for entrants to the space," said Mary Furlong, executive producer of WIN and CEO of Mary Furlong & Associates. "Our summit is carefully curated to help attendees navigate regulatory, privacy and reimbursement issues and remain at the forefront of trends in aging while also helping innovators scale their solutions with the right U.S. and international partners."

Furlong added, "The private companies, federal agencies and nonprofits who attend also benefit by connecting with this curated collection of innovators. Since technology moves fast and so many players enter the space on a daily basis, it is a resource drain for organizations to meet with every start-up company so attending this conference cuts through the clutter to identify best of breed and pursue quicker yet quality partnerships."

Joining the notable keynote speakers Nancy LeaMond of AARP and George Vradenburg of UsAgainstAlzheimer's, will be an impressive line-up of panel speakers from the federal government: James Parker, senior advisor to the Secretary for Health Reform and director of the Office of Health Reform at the U.S. Department of Health & Human Services; Melanie Egorin, deputy health staff director, U.S. House of Representatives Committee on Ways and Means; Todd Haim, chief of the Office of Small Business Research, National Institute on Aging and Vijeth Iyengar, brain health lead and technical advisor to the Deputy Assistant Secretary

for Aging at the Administration for Community Living, U.S. Department of Health and Human

Services. They join lead investors in the longevity market, Dan Hermann, president and CEO, head of Investment Banking forZiegler Link-Age Longevity Fund and Jake Nice, principal,Nationwide Ventures; along with top aging technology entrepreneurs such as CareLinx, Posit Science, Ageless Innovation, PS Salon & Spa and 12 global companies from countries including Japan, Israel and Sweden.

"Through its small business programs, the National Institute on Aging at the National Institutes of Health provided more than $100 million in funding to start up organizations in FY 2019 alone," said Todd Haim, Ph.D., chief, NIA Office of Small Business Research. "For successful applicants, our programs are an excellent source of seed funding for the further development of innovations geared toward older adult health and well-being."

The full agenda and summit details are here. Summit registration is available here. Key sponsors for the Summit include: AARP, Ageless Innovation, CareLinx, Center for Aging + Brain Health Innovation, Sodexo, Thrive Alliance, Posit Science, Audio Cardio, LivPact, CarePredict, Stay Smart Care, LLC., AloeCare, Embodied Labs, Nationwide, It's Never Too Late, VitalTech and Home Instead.

About Mary Furlong & Associates For 17 years, Mary Furlong & Associates (MFA), headquartered in the San Francisco Bay area, has developed strategies for marketing and business development for companies focused on opportunities with the senior and baby boomer markets and the longevity economy. Dr. Furlong is the executive producer of three conferences annually: What's Next Boomer Business Summit, Silicon Valley Boomer Venture Summit, and Washington Innovation in Longevity Summit. She also co-produces What's Next Canada and is scheduled to add a fourth conference in Paris, France, focused on international aging.

Contact Information: Ben Adkins 230490@email4pr.com 502.619.4267

SOURCE Mary Furlong & Associates

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How to live longer: This diet has been proven to help you live longer and stave off cancer – Express

Tuesday, December 10th, 2019

The age-old secret to a longer life really comes down to a healthy lifestyle including regular exercise, limiting alcohol intake, not smoking and eating a healthy balanced diet. Good nutrition is key to leading a healthy lifestyle. The foods a person eats gives the body information and materials they need to function properly. If a person eats too much food, or food that gives the body the wrong instructions, their risk of potentially life-threatening diseases increases and lifespan shortens. What is the best diet to help a person live a long, healthy life and reduce their risk of deadly diseases?

A study has been published in the JAMA Internal Medicine Journal and reignites debate around increasingly popular vegan diets amid conflicting medical advice and evidence over the impact of ones health.

The study found every three percent in calories form plant protein was found to reduce risk of death by 10 percent.

The figure rises to 12 percent for risk of dying from heart disease. By contrast, raising the share of animal protein in ones diet by 10 percent led to a two percent higher risk of death from all causes.

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Experts recommend eating more plant-based foods, such as fruits, vegetables and whole grains. Lean protein and low-fat dairy products are also recommended.

Numerous research suggests eating at least seven portions of fresh fruits and vegetables per day may lower the risk of dying from cancer by up to 15 percent.

Dr Mingyang Song said: Overall, studies have supported the importance of the sources of dietary protein for long-term health outcomes.

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Around the Bloc – 10 December – Transitions Online

Tuesday, December 10th, 2019

Todays regional roundup: Turkey in a tizzy over NATO plans; Albania opens probe into deadly earthquake; Kazakhs and China; long-lived Azeris; and the Putin-Zelenskiy summit.10 December 2019

Ankara Threatens to Block NATOs Eastern Defense Plan

Poland will not stand for Turkey walking back its support for NATOs defense plan for Poland and the Baltics, an aide to President Andrzej Duda said yesterday. There is no going back from the decision made at the NATO summit last week, Krzysztof Szczerski told Reuters. After the summit, NATO Secretary General Jens Stoltenberg said Turkey had withdrawn its objections to the plan, although Turkish President Recep Tayyip Erdogan said Turkey expected support from the alliance in its fight against Syrian Kurdish forces it considers to be terrorists. Turkish Foreign Minister Mevlut Cavusoglu then escalated the rhetoric, saying, Ankara will block the plan until it receives a proposal for a defense plan for Turkey, which must be in line with the Turkish viewpoint on YPG, Euractiv quotes him as saying. The Syrian Kurdish YPG force is a main fighting arm of the U.S.-backed Syrian Democratic Forces, Reuters writes. Duda and Baltic defense ministers appeared to be more optimistic for a solution on the matter during the London summit, although Eastern European officials were cautious about the prospects for compromise, Euractiv writes.

Albania Counts the Toll of Deadly November Quake

The earthquake that hit Albania last month totally destroyed at least 261 buildings, Prime Minister Edi Rama said yesterday. Durres, the countrys second city, was worst hit by the 6.4-magnitude quake that struck in the early morning of 26 November. In Durres, 438 buildings are so badly damaged they must be demolished, Rama said. The quake claimed 51 lives, Xinhua reports. Some 500 engineers, along with experts from 11 countries, are inspecting the affected areas, Rama said. Last week, newly appointed Albanian Prosecutor General Olsian Cela said prosecutors in Durres had opened an investigation into who should be held responsible for the damage, Radio Tirana International reported. There are people who have violated the law and many have lost their lives. Responsibility will fall either [on] the builder or [on] the official. There will be no hesitation in any case, Cela said. The minister of state for relations with parliament, Elisa Spiropali, who is also the governments spokeswoman, said new neighborhoods will be built to replace damaged housing, RTI reports today. She also chided the media for spreading the lie that the state has no money for civil emergencies.

Two Ethnic Kazakhs Fight Deportation to China

Two ethnic Kazakhs from Chinas Xinjiang region are facing deportation from Kazakhstan in spite of warnings they could be tortured if returned to China. The men, Murager Alimuly and Qaster Musakhanuly, crossed into Kazakhstan illegally on 1 October and were given asylum seeker status at the end of the month, The Diplomat reported. But as RFE/RL writes, the deputy chief of Kazakhstans National Security Committee said last week that the pair, currently being held in pre-trial detention, will be deported. Three Kazakh opposition activists, Zhanbolat Mamai, Yrysbek Toqtasyn, and Tolegen Zhukeev, told the media yesterday the men will definitely face torture and possible death back in China. China is holding, by some estimates, a million or more Muslims in re-education camps in the predominantly Muslim Xinjiang region. Beijing has long accused the majority Uighur community in Xinjiang of Islamist and separatist tendencies. The few officials who have acknowledged the existence of the camp system say they are aimed at instilling loyalty to the regime, and deny reports that Muslims in the region are subject to persecution. Kazakhs are the second-largest Turkic-speaking community in Xinjiang, RFE writes.

Ukraine Summit Brings Scant Progress

Ukrainian President Volodymyr Zelenskiy rammed home his no-compromise position on autonomy for Russian-backed separatists in the aftermath of yesterdays meeting with the Russian, French, and German leaders. There were no new ideas on resolving the conflict in eastern Ukraine, although Zelenskiy and Russian President Vladimir Putin agreed another ceasefire in the contested Donbas region, the Financial Times writes. They made no progress on the question that has dogged peacemaking efforts throughout the nearly six years of conflict that of a special dispensation for separatist areas in the Donbas. Before elections can be held in those regions, Kyiv must regain control of their borders, Zelenskiy said at a briefing after yesterdays Paris summit, Ukraines broadcaster 112 reports. "For Ukraine, the border is a security issue; for Russia, it is a policy, he said, adding that he and Putin finally agreed on the need to talk further. The four leaders also agreed on removing all minefields, further exchanges of prisoners, and military disengagement from three areas by next March, according to the FT.

Visit Lerik, Where the Living is Easy

Azerbaijani researchers recently conducted a study of the countrys centenarians, hoping to shed light on the legendary longevity of people in some isolated areas. There are certain generations of long-living people, Sevinj Huseynova, lead researcher at the Azerbaijani Institute of Physiologys longevity laboratory, told Trend last spring, as cited by Baku-based Caspian News. If the ecological environment is good, the gene is not lost and is inherited. Inhabitants of three districts in the south, along with Nagorno-Karabakh, are longer-lived than those in and around Baku, the study found. People living in the Talysh Mountains in the southern Lerik district are famous for exceptionally long lives and Lerik town boasts the worlds only Museum of Longevity, according to CNN. This two-room exhibition was built in 1991 and renovated in 2010. Some exhibits claim to document the incredible 168-year life of shepherd Shirali Muslumov. His 95-year-old daughter, Halima Qambarova, said while she might not match his record, she at least hopes to live to the age of 150, like her grandfather, or 130, like her aunt, CNN writes. Lifespans also run long among indigenous groups in Russias North Caucasus republics, where the Ingush often live to 80, Russia Beyond has reported. On the western flank of the region, the Abkhaz are also famed for their healthful diet and long lives.

Compiled by Ky Krauthamer

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How to live longer: This activity has been proven to boost life expectancy – Express

Tuesday, December 10th, 2019

Longer life expectancy is found among those who do a certain activity. Scientists say it not only boosts life expectancy but reduces the risk of obesity, high blood pressure, high cholesterol, disability, type 2 diabetes, heart disease and cancer. It also improves aerobic endurance, heart function, balance and metabolism. Best of all it requires no equipment, free of charge and promises some stunning scenery along the way.

Numerous studies have proven that running has a lot of health benefits. In fact, running once a week could help a person live longer, according to a November 2019 study published in the British Journal of Sports Medicine.

The study examined and analysed available data about the health benefits of running and found that running, even just 50 minutes per week, was associated with a 27 percent lower risk of death from all causes, a 30 percent reduced risk of death from heart disease and a 23 percent lower risk of death from cancer.

READ MORE: How to live longer: Following this diet once a month could increase your life expectancy

Researchers of the study noted: Increased rates of participation in running, regardless of its dose, would probably lead to substantial improvements in population health and longevity.

Fourteen studies were analysed with more than 232,000 people whose health was tracked between 5.5 and 35 years.

The collective data showed that any amount of running was associated with a reduce risk of death from heart disease or cancer.

DONT MISS

The reason behind how running helps reduce risk of deadly diseases and premature death is unclear and the study doesnt establish cause and effect.

Even so, the study proves that any amount of running has major benefits to the body and overall health.

Previous studies have found that fast walking also has a myriad of physical and cognitive health benefits.

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Purdue is looking for your dog to participate in a national scientific study. Here’s how. – Journal & Courier

Tuesday, December 10th, 2019

Purdue is looking for dogs to participate in a national study on the health and wellness of dogs.(Photo: provided by Purdue)

WEST LAFAYETTE, Ind. Purdue is looking for dogs. More specifically, your dog to volunteer as a participant in a national study that will be looking at the general health and wellness of dogs.

The Dog Aging Project is a collaboration between more than 40 scientists and researchers across the U.S. and will be looking at dogs of all breeds, mixes and ages. At Purdue, Audrey Ruple, an assistant professor of One Health Epidemiology in the College of Health and Human Sciences, is one the researchers leading the study and is hoping to recruit dogs from across Indiana.

Ruple, who is a veterinary epidemiologist specializing in dogs as a model of human health, said the goal of the study is to examine factors that maximize the health and longevity of dogs, which can be linked to the health and longevity of humans.

Humans and dogs have more in common than we might think sharing 650 million base pairs of genetic information with the canines which Ruple said makes the animals useful to study human disease processes. Dogs also have a sophisticated health care system, comparable to the human health care system.

Dogs are unique because they share our environment, Ruple said. They live in our homes, drink our water and sometimes eat our human food. We both have similarities, and we see a lot of similar diseases and health issues.

The Dog Aging Project will follow participating dogs to watch how different environmental and biological factors can affect longevity for the next 10 years, although the schedule could extend beyond that time. The research hopes to look at specifics that could affect longevity, including an individuals genome, proteome, microbiome, demographics and environmental factors.

Owners who nominate their dogs to participate in the study will complete a 200-question health and lifestyle survey as well as submit electronic medial records, likely through the dogs veterinarian. The study isnt limiting the types of dogs participating eitherdogs of all breeds, mixes and sizes are encouraged to participate.

Neither the dogs nor owners will be compensated for the research, butthere is no cost to participate. Researchers will be working closely with the primary care veterinarians of the dogs, who will be expected to visit for their regular annual examination.

Ruple said the study is a citizen scientist project, meaning the owners of participating dogs are considered to be research partners in the study.

The study is funded by a five-year grant from the National Institute of Aging, which is part of the National Institute of Health, as well as private donations.

The Dog Aging Project hopes to enroll tens of thousands of dogs to research by the end of 2020.

People can take a part in the scientific process, whether its for human health or dog health, Ruple said. Through this study, we can learn to not only be better stewards of their existence, but also for our own.

TO APPLY:For more information on the Dog Aging Project or to nominate your dog, visithttps://dogagingproject.org/

Emily DeLetter is a news reporter for the Journal & Courier. Contact her at (765) 420-5205 or via email at edeletter@jconline.com. Follow her on Twitter at @EmilyDeLetter.

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‘Biologically younger’ people who defy their real age often have 5 things in common – INSIDER

Tuesday, December 10th, 2019

Dan Buettner, the man who popularized the idea that there are five "Blue Zones" around the world where people live some of the longest, healthiest, happiest lives, says that people living in those zones all share five common traits.

"It is this interconnected web of characteristics that keep people doing the right things for long enough, and avoiding the wrong things," Buettner said.

Blue Zone residents, whether they're home in Loma Linda, California; Ikaria, Greece; Okinawa, Japan; Sardinia, Italy; or Nicoya, Costa Rica, all eat very little meat. Instead, they subsist on a largely plant-based diet filled with beans, nuts, and cruciferous vegetables, which Buettner has written about in a new cookbook.

But that diet is only, at best, about 50% of the Blue Zones longevity equation.

"It's the scaffolding, this collagen," Buettner told Insider. "That keeps people eating the right way for long enough."

Here are the other four core principles that sustain life in the Blue Zones.

Dan Buettner pioneered the idea that the world includes five "Blue Zones." Crystal Cox/Business Insider

Going to the gym is not a Blue Zones tradition.

"They don't exercise," Buettner said. Instead, people in Blue Zones are "nudged" into movement in little bursts throughout the day, by force of habit and, also, necessity.

"They're walking, or they're in their garden, or they're doing things by hand," he said.

In Buettner's home state of Minnesota, he credits shoveling the walks in winter, digging, weeding, and watering a garden in the summer with keeping him spry.

"I don't have a garage door opener, I open it by hand," he said. "To the extent that I can, I use hand-operated tools."

He's turned the inside of his house into a little mini Blue Zone, too, where he's getting up and moving all year round.

"I put the TV room on the third floor," Buettner told me, "So every time if I want a snack, I'd go up and down stairs."

The technique is one he's honed by studying life in the Blue Zones.

"It's being mindful of how to engineer little bursts of physical activity," he said.

Research has shown that such little energetic busts throughout the day can do a lot for overall fitness. One study published in January showed that even 20 second-long, vigorous stair-climbing exercise "snacks" spread out over the course of a day can improve fitness.

"It's a reminder to people that small bouts of activity can be effective," lead study author Martin Gibala told Insider when his team's research came out. "They add up over time."

Gallo Pinto ("spotted rooster") is a traditional breakfast meal in Costa Rica, made from leftover rice cooked with beans. Beans and rice are a complete protein. Kevin Schafer / Getty Images

In Japan they call it "ikigai," and in Costa Rica it's a "plan de vida." The words literally translate to "reason to live," and "life plan," respectively, and both concepts help residents of the Blue Zones feel there's a reason to get up and do what needs to get done each morning.

Studies also suggestthat a sense of purpose in life is associated with fewer strokes and less frequent heart attacks among people with heart disease, as well as more use of preventive care.

One 2017 investigation from researchers at Harvard concluded that a sense of purpose in life is associated with better "physical function among older adults," including better grip strength and faster walking.

Good health and happiness can be contagious, and obesity can too.

In Japan's Blue Zone, people form social groups called "moai" to help them get through life.

"Parents cluster their children in groups of five, and send them through life together," as Buettner explained in a recent video. "They support each other, and share life's fortunes and woes."

The trend is not unique to the Japanese. In Loma Linda, California, Blue Zoners (many of whom are Seventh-day Adventists) are more likely to share vegetarian potluck meals than meet each other over a Chipotle burrito or McDonald's fries.

Buettner has created Blue Zones "Projects" across the US, where cities and towns enact policies that change the entire environment that people live in.

"We're genetically hardwired to crave sugar, crave fat, crave salt, take rest whenever we can," Buettner said. "We've just engineered this environment where you don't have to move. You're constantly cooled down or heated up ... and you cannot escape chips and sodas and pizzas and burgers and fries."

In cities from Minnesota to Texas, he's helped create healthier communities where policies favor fruits and vegetables over junk food, people form walking groups to move around town and shed pounds together, and many quit smoking, too.

All of this, he said, adds up to troupes of "biologically younger" people, who not only weigh less, but suffer fewer health issues as they age.

"At every decade, you have more energy," he said.

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AI Will Drive The Multi-Trillion Dollar Longevity Economy – Forbes

Saturday, December 7th, 2019

World Longevity Economy Size Projections, current USD

AI for Longevity has more potential to increase healthy Longevity in the short term than any other sector. The application of AI for Longevity will bring the greatest real-world benefits and will be the main driver of progress in the widespread extension of healthy Longevity. The global spending power of people aged 60 and over is anticipated to reach $15 trillion annually by 2020. The Longevity industry will dwarf all other industries in both size and market capitalization, reshape the globalfinancial system, and disrupt the business modelsof pension funds, insurance companies, investment banks, and entire national economies.

Longevity has become a recurring topic in analytical reports from leading financial institutions such as CitiBank, UBS Group, Julius Baer, and Barclays. At the recent AI for Longevity Summit in London, top executives from Prudential, HSBC, AXA Insurance, NVIDIA, Microsoft, Babylon Health, Insilico Medicine, Longevity.Capital, Longevity Vision Fund, Juvenescence, Deep Knowledge Ventures, and the UK All-Party Parliamentary Group for Longevity came together to discuss the Longevity Industry. International policymakers and senior corporate executives shared learnings from Japan, Israel, Switzerland, the US, and the UK and exchanged ideas on beginning to work together in a new social contract to enhance global prosperity equitably.

The 7th Continent - 1 Billion People in Retirement Globally

Switzerland is one of the most longevity progressive countries in the world with both high investment in biotechnology and the capacity to integrate AI into its economic, financial, and healthcare systems. Switzerland has the potential to be a world leader in both the Global Longevity Industry and the 4th Industrial Revolution. There are currently 100 companies, 80 investors, 50 financial companies, 35 research labs, 20 precision medicine clinics, 15 nonprofits, and 10 governmental organizations in the Swiss Longevity Industry. Switzerland is in an excellent position to retain its leading position by focusing on the optimal assembly of its existing resources to transform the challenge of demographic aging into a national asset.

Switzerland has a large aging population and Swiss investment banks are acutely aware of the oncoming demographic challenge. Switzerland is one of the most efficiently regulated and supervised financial centers in the world and has been leading transformative developments emerging from the digitalization of its banking and financial sector. Longevity-progressive countries typically have large aging populations, and aging populations have two longevity-progressive benefits: voting power and spending power.

Longevity Industry in Switzerland 2019

The digitization of finance, and novel financial systems which treat Longevity as a dividend, will play an integral role in the Longevity economy. According to a recent report by Aging Analytics Agency, Switzerland has the elements necessary to become a leading Longevity financial hub, including factors such as a lean political system that facilitates rapid implementation of integrated government programs, a strong research environment for geroscience, a strong research and business environment for digital health, and most importantly, international financial prowess.

Switzerland has the ability to develop several Longevity specific programs over the next several years. One program is a Longevity progressive pension system and insurance company ecosystem that accounts for both population aging (which threatens to destabilize the current business models of insurance companies and pension funds) and the potential for widespread healthspan extension. Another program is a national strategy for intensively developing Geroscience and FinTech to a state so advanced that it propels Switzerland into a central role in the international Longevity business ecosystem and a global leader in Longevity Finance. Switzerland is leading the digitization of financial markets and establishing itself as a catalyst for financial innovation on a global level. According to Aging Analytics Agency, 10% of all European FinTech enterprises are located in Switzerland.

Switzerland has a strong and productive geroscience community and has gained prominence among investors as a global biotech hub and hotbed of innovation. The Swiss Institute for Bioinformatics has recently identified large numbers of genetic markers directly linked to human life expectancy. Switzerland is also home to the prestigious Vontobel Prize for Aging Research.

The Convergence of 5 Mega Trends

BioValley

Switzerland is situated at one end of the BioValley - one of the leading life science clusters in Europe. This cluster is unique in that it spans across three countries, Switzerland, Germany and France, and includes Basel, a global life science hub. BioValley brings together important ingredients for a successful biotech cluster including a concentration of companies, rich availability of skills, experience within Life Sciences, and a world class research base. The cluster in Switzerland has in excess of 50,000 people working in the life sciences field including 15,000 scientists. There are 600 companies in the cluster developing therapeutic, diagnostic or medical devices to address a wide range of diseases in multiple therapeutic classes. There are 100,000 students enrolled in 10 universities and research institutions including University of Basel, Max Planck Institute, and Freiburg University. The cluster has produced a number of spin-out companies supported by a financial network including both public and private financing initiatives as well as traditional venture capital and private equity. The entire process of drug development is covered in the region, from research through to clinical and drug development, and manufacturing.

Longevity AI Consortium Expands to Switzerland

Longevity AI Consortium King's College London

In November 2019, Europes firstLongevity AI Consortium(LAIC)launched at King's College London. LAIC is currently developing collaborative research projects withDynamics of Healthy Ageing (DynAge)and theDigital Society Initiative (DSI)at the University of Zurich. The research will utilize AI technologies to predict the future cognitive ability of individuals using multimodal neuroimaging and risk factor data. Academics in Zurich will work in collaboration with colleagues at the Institute of Psychiatry, Psychology, and Neuroscience at King's College London. LAIC plans to establish several collaborative projects with the University of Zurich in 2020. The joint R&D between Ageing Research at Kings and University of Zurich forms the first phase of the global Longevity AI Consortium that will eventually be extended to Israel, Singapore, Japan and the US.

The Longevity Industry

AgeTech

FinTech banks are redefining the banking industry by connecting with a new generation of mobile-first consumers. However, FinTech banks are focusing on consumers who are middle-age and younger, not on the 1 billion people in retirement and the $15 trillion dollar market opportunity. As the share of the population over 60 increases, Swiss banks are lagging behind in finding solutions for this age group. Traditional banks, as opposed to challenger banks, are making their first steps in AgeTech, adapting their infrastructure for people over 60.

WealthTech

The WealthTech Industry refers to a new generation of financial technology companies that create digital solutions to transform the investment and asset management industry. New companies have arrived on the scene offering advice based on AI and big data, micro-investment platforms, and trading solutions based on social networks. A growing aging population is one of the main drivers of innovation in WealthTech. Financial services innovators have an opportunity to enhance the financial lives of individuals over 60 by designing new solutions and adapting existing products and services for them. This is an opportunity to implement innovations that address financial health challenges head on.

Financial Wellness

As a core component of its mission to develop Switzerland into a leading international Longevity Financial Industry hub, Longevity Swiss Foundation plans on roadmapping the development of AI Centers for Financial Wellness. Whereas the proposed AI Centers for Longevity would focus on optimizing health, these centers would focus on the application of AI to the creation of methods and technologies to promote wellness in other areas including financial wellness, continuing education, psychological well being, neuroplasticity, and active social involvement. The planned development of AI Centers for Financial Wellness will enable financial stability over extended periods of healthy Longevity for Swiss citizens.

Switzerland could become the center of the Longevity Financial Industry. Given its geographic size and its reliance on international cooperation, its function in the Longevity Industry will be as a small but important node. Due to its status as an international BioTech epicenter and its reputation as one of the most progressive countries in terms of its financial industry, the prospects for Switzerland to lead the world in the development of its Longevity Financial Industry are strong.

Today, change occurs at the intersection of two or more scientific and technological domains. We are at the beginning of a trend where the degree of complexity and the number of convergence points will increase exponentially. The convergence of AI, advanced data science, and Longevity research will accelerate important medical breakthroughs that will benefit all humans. In the next decade, the Longevity Industry will impact many areas of our lives. Longevity policies enacted by governments and changes in the global financial industry will transform society. Achieving small but practical results in Longevity distributed at scale will have enormous and multiplicative effects on society. Extending the functional lifespan of humans by just one year will decrease suffering for tens of millions of people and will improve the quality of life for billions of people.

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You Can Improve Longevity By Having This Diet At Least Once A Month – International Business Times

Saturday, December 7th, 2019

In a recent study undertaken by scientists from the National Institutes of Health and National Institute of Aging, researchers found the secret to longevity is linked with meal times.

The researchers separated 292 male mice into two groups and gave them different diets. They also examined how altering the meal times affected the life expectancy of the mice. At the end of the study period, the scientists found the results to be very impressive and concluded that the same might be true for humans. happy man longevity Photo: rottonara - Pixabay

They said the findings provided a beacon of hope for future studies and at the same time, suggested a particular diet to help improve longevity. This study, which was participated in part by scientists from the Pennington Biomedical Research Centre and the University of Wisconsin-Madison, analyzed how longer fasting times could boost health and longevity. Researchers noted that increasing the time between meals improved the overall health of the male mice. They also lived longer compared to the other group who were fed and ate more frequently.

The scientists also report that health and life span greatly improved with increased fasting times, notwithstanding the type of food the mice ate or how many calories the food contained.Dr. Richard J. Hodes, a director at the NIA, said that the study revealed that the group of mice that consumed only one meal daily appears to enjoy a longer lifespan. They also seem to have better outcomes for age-related ailments like liver disease and a number of metabolic disorders.

He also said that the fascinating results using lab mice as the model which revealed the relationship of fasting and feeding time length and total caloric intake deserve a closer examination.

Dr. Rafael de Cabo, the studys lead author and Translational Gerontology Branch chief of the NIA Intramural Research Program, said increasing daily fasting times improved the overall health of male mice. He also said that their survival chances in a number of age-related ailments also increased. These positive results occurred regardless of the caloric intake and the type of diet the mice have.

The lead author hypothesized that the extended fasting period might have enabled the maintenance and repair mechanisms of the mices bodies to kick into place. Such a process would have been absent had the mice ate food continuously.Researchers of the study also revealed the results seem to suggest that those who are able to fast at least once a month may enjoy a longer and healthier life.

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103-year-old shares secrets to longevity: Exercise and wine – msnNOW

Saturday, December 7th, 2019

Courtesy South Shore YMCA Ruth Kundsin, 103, works out with her personal trainer Dick Raymond at the South Shore YMCA in Quincy, Massachusetts.

People lifting weights at a gym in suburban Boston can be forgiven if they have no clue the energetic woman working out next to them is 103 years old.

Ruth Kundsins exercise routine includes cardio and strength training, a lifestyle thats more active now than the decades she spent working as a microbiologist only reluctantly retiring in her 80s.

She still lives on her own, loves parties and works out with a personal trainer every Friday at the South Shore YMCA in Quincy, Massachusetts.

I feel better afterwards and I think its keeping me vertical, Kundsin told TODAY, expressing surprise at all the excitement about her centenarian status.

Its really funny to me. I think Ive gotten more accolades for my age than I have for my science and thats sort of strange because you have nothing to do with your age. I mean, you just age, but the science I really worked hard on.

Dick Raymond, who has been her personal trainer for 10 years, said weights are the most important part of her routine.

We work every part of her body trying to keep her strong, Raymond, 69, noted. The older you get, the more you need exercise because you lose strength as you age. You can prevent that you can get better at any age.

Heres what Kundsin attributes to her longevity:

Kundsin described herself as having a very upbeat, optimistic, happy outlook on life. If something disturbs her, she gets over it, she said.

Its very important to have something to look forward to. If you dont have anything to look forward to, life is bleak and dull. But it seems like I always have something to look forward to and if there isnt anything, I make it, like I throw a party, Kundsin said.

I know that no matter how bad I feel, in a little while, Ill be feeling pretty good. I dont really worry about anything any great length of time.

The daughter of Latvian immigrants, Kundsin received a doctorate of science from Harvard School of Public Health in 1958.

Kundsin felt passionate about her work as a scientist and insisted on working even though it upset her family at a time when women were expected to stay home with their children.

She was the first mother to work in her community, facing intense scrutiny from her neighbors. Even Kundsins husband didnt want her to work, but she got her own way.

Thank goodness. Now I know it was the right thing to do, she said. Its a satisfaction to have a job I loved my work.

Kundsin had 150 papers published in scientific journals and wrote five books. She worked as an associate professor at Harvard Medical School until she was 81.

Scientific work is sedentary, so after spending much of her life bent over a microscope, Kundsin decided she had to make up for it when she retired.

When an acquaintance invited her to come to a gym, she thought it would be fun and has been exercising regularly ever since. She particularly liked swimming, taking part in Senior Games and competing at the national level three times.

She started working out with Raymond at age 93. The personal trainer focuses on having her do exercises that are challenging for her because challenging things are what improve you. Easy things dont improve you, he said.

Besides her weekly workouts, Kundsin cooks for herself and takes care of her house, doing chores and climbing up and down stairs, which Dick approves of, she said.

Kundsin isnt the first centenarian Raymond has worked with. He at one point also trained his father, who recently passed away at 101.

Unlike many centenarians TODAY has profiled, Kundsin smoked cigarettes for many years and didnt quit until her 70s. Still, she hasnt had any major health problems like cancer or heart disease, she said. Its only within the past year that shes started using a cane because of balance issues.

Kundsin doesnt eat beef, but otherwise does nothing special when it comes to her diet.

Influenced by Raymonds advice, she now eats oatmeal topped with lots of fruit for breakfast and has started avoiding sugar after a lifetime of eating desserts.

She drinks a glass of wine every night not because she loves it but because she believes its good for health. Indeed, research of people who lived to 90 and beyond found those who drank moderate amounts of alcohol lived longer than those who abstained.

I should be drinking red wine, but I think its a little strong for me so I drink white wine. I prefer champagne, Kundsin said.

Related Video: 104-Year-Old Runner Shares Her Longevity Tips (Provided by Today)

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How to live longer: Following this diet once a month could increase your life expectancy – Express

Saturday, December 7th, 2019

The secret to long life expectancy is to follow a healthy lifestyle - regularly exercising, limiting alcohol intake, not smoking and eating a healthy balanced diet. When it comes to eating a healthy diet, the NHS recommends eating at least five portions of a variety of fruit and vegetables every day, basing meals on higher fibre starchy foods like potatoes, bread, rice or pasta, having some dairy or dairy alternatives, some protein, choosing unsaturated oils and spreads, and eating them in small amounts, and drinking plenty of fluids. A new study also suggests a different approach to meal times and how it could impact on your health.

In the study with the National Institute of Ageing (NIA) and the National Institutes of Health, longer daily fasting times and how it could improve health and longevity was analysed. The study noted: Increasing time between meals made male mice healthier overall and live longer compared to mice who at more frequently. Scientists from the University of Wisconsin-Madison and the Pennington Biomedical Research Centre, Baton Rouge, Louisiana , reports that health and longevity improved with increased fasting time, regardless of what the mice ate or how many calories they consumed. https://www.sciencedaily.com/releases/2018/09/180906123305.htm

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NIA director, Dr Richard J. Hodes said: This study showed that mice who ate one meal per day and thus had the longest fasting period, seemed to have a longer lifespan and better outcomes for common age-related liver disease and metabolic disorders.

"These intriguing results in an animal model show that the interplay of total caloric intake and the length of feeding and fasting periods deserves a closer look.

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Families with long, healthy life spans focus of $68 million grant – Washington University School of Medicine in St. Louis

Saturday, December 7th, 2019

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Long life study explores genetics of extreme longevity

A new grant from the National Institute on Aging of the National Institutes of Health (NIH) supports research into the mysteries of extreme longevity. Researchers at Washington University School of Medicine in St. Louis are leading the Long Life Family Study, which includes several generations of families with unusual concentrations of long-lived individuals. The goal is to uncover genetic factors that play roles in long life spans.

Washington University School of Medicine in St. Louis has received a $68 million grant to investigate and discover what contributes to extreme longevity. The researchers are studying hundreds of families over several generations with individuals who have had exceptionally long lives. Many of these families have unusual concentrations of people living to at least age 100.

The goal of the Long Life Family Study, funded by the National Institute on Aging of the National Institutes of Health (NIH), is to identify genetic factors that contribute to exceptional longevity. Such information could lead to new therapeutics or other health innovations to help people live longer, healthier lives.

These families provide a unique opportunity for finding genetic links to long life spans, said principal investigator Michael A. Province, PhD, a Washington University professor of genetics. Remarkably, many study participants in the older generations are unusually healthy for their ages. We think we will find clues in their DNA that suggest how they might be protected from common diseases, such as diabetes or Alzheimers disease or, at the very least, uncover genetic factors that might delay the onset of these health problems.

The School of Medicine is the coordinating center for the project, which has field centers at Boston University, Columbia University, the University of Pittsburgh and the University of Southern Denmark. Province and Mary K. Wojczynski, PhD, an assistant professor of genetics at Washington University, lead the primary site and coordinate collaborations among the field sites and the University of Minnesota, where the laboratory for analyzing blood samples is located.

The study includes almost 5,000 individuals from three generations of 539 families across the United States and Denmark, first recruited from 2006 through 2009. The average age of representatives of the oldest generation in the study was 90 at that time, with some individuals exceeding 110. Those in the second generation of these families now average over 70 years of age, and the grandchildren of the oldest group are now in their 50s, on average. Studying multiple generations of families with histories of long lives presents the opportunity to study individuals who have a greater chance of reaching older ages. In particular, it provides the ability to study such individuals when they are younger and not yet obviously different from those with shorter life spans.

When we study long-lived people, we would really like to be able to travel back in time and study them before they reach older ages to see how they might differ from the general population when those differences might not yet be obvious, Province said. Our earlier findings from this study have shown that individuals in the second generation are healthier, on average, than individuals from families with more typical longevity, when measured, for example, in middle age. But these healthier traits vary by family. For example, some long-lived families might tend to have lower blood pressure while others might have better cognition into later life, and still others might have better lung function or grip strength. Across these families, there is no single factor that stands out as the main reason for the long health and life spans.

The researchers suspect this variability may be linked to specific rare genetic variants that may protect such families from the harmful effects of aging in a variety of ways. The new funding will support whole genome sequencing of study participants in an effort to identify special protective variations in the DNA.

The researchers also will study the consequences of such differences in DNA through analyzing what effects they might have on the proteins, metabolites and other molecules that have a direct impact on the bodys biology. Such measures change with age, and the researchers are interested in comparing these with more average populations over their life spans. The comparison group is composed of participants from the well-known Framingham Heart Study, which has been tracking the health of multiple generations of families living in Framingham, Mass., since that study began in 1948. The researchers said less than 1% of families participating in the Framingham Heart Study meet the longevity criteria of the Long Life Family Study.

One genetic characteristic that stands out in some but not all long-lived families is the length of telomeres, or the end caps on chromosomes that protect the DNA from damage. Every time a cell divides, the telomeres get a little shorter, and shorter telomeres have been associated with chronic diseases, such as diabetes, heart disease, dementia and other disorders common among elderly people. Long-lived families seem to have longer than average telomeres.

Telomere length might be one key component of healthy aging, Province said. There is evidence that healthy behaviors like exercise can protect telomere length or even extend it. But there is a genetic component to it as well. Some people just naturally have longer telomeres, or at least appear to have resilient telomeres. And that is the case in many of the families were studying. Based on that data, we have honed in on a gene that could be involved in telomere length, and this new grant will help us explore that possibility and other new avenues further.

Washington University School of Medicines 1,500 faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Childrens hospitals. The School of Medicine is a leader in medical research, teaching and patient care, ranking among the top 10 medical schools in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Childrens hospitals, the School of Medicine is linked to BJC HealthCare.

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