StemCell Therapy

A new NUS research at Bia-Echo Asia Centre for Reproductive Longevity and Equality will study ways to advance female fertility, lifespan and health-span

The Centre, to be established at the Yong Loo Lin School of Medicine at Singapore's National University of Singapore (NUS), was made possible by an $8 million gift from the Bia-Echo Foundation, based in the USA, whose founder is attorney and entrepreneur Nicole Shanahan.

Research initiatives at the Centre will be led by scientists and clinicians from NUS Medicine and other institutions here as well as the Asia-Pacific, US and Europe, and specializing in womens reproductive health, aging, and digital medicine. The effort will seek to find ways to improve and lengthen female reproductive health and longevity, helping women to preserve and improve their reproductive systems for conception and general health, potentially enabling women to conceive safely in their later years.

Declining fertility and associated health risks

The issue of female fertility has come into sharp focus in recent years, with more women getting married later and having children later in life. In Singapore, the number of women giving birth in their 40s has almost doubled in the last three to four decades, according to data from Singapores Department of Statistics.

The number of births per 1000 women aged between 40-45 was 9.9 in 2019, nearly double the number recorded between 1980 to 1989. However, conception is an uphill task for women above 40 as fertility declines with age. The chances of natural conception fall to less than 5% and this also often comes with serious health risks and complications, such as miscarriages and premature live births, and higher chances of having a child with Downs Syndrome.

Furthermore, as women in their 40s approach menopause, they also face increasing health issues such as metabolic diseases, neurocognitive decline, osteoporosis, and poor urogenital health, which result in poorer general health. Current medical approaches to assist conception include the use of fertility drugs, as well as reproductive assistance technologies. Their efficacy, however, remains limited as the woman ages.

Bia-Echo Asia Centre for Reproductive Longevity and Equality:

The centerspecificallyaims to;

The vision of the US-based Bia-Echo Foundation, a private enterprise founded to accelerate social change to establish a fair and equitable society for generations to thrive, aligns with that of the NUS medical school, said its Dean, Professor Chong Yap Seng.

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Bia-Echo Foundation invest $8M in Singapore to study women's reproductive longevity - BSA bureau

Growing old is hard. The aging process is not kind on us. The worst bit is, age creeps up on you so quietly that you dont even realize it until one day you look in the mirror and barely recognize yourself. However, all is not lost. Practicing healthier habits can positively affect the aging process and help you slow down if you want to turn back the clocknow.

Losing weight is number one on our list for obvious reasons. A trim body not only gives the illusion of youth, it can add years to your life. According to some research published in the American Journal of Clinical Nutrition, there is a direct link between obesity and increased risk of life-threatening diseases like heart problems, diabetes, embolisms, and even some forms of cancer.

Extra weight also makes you sluggish and lazy. Luckily, the research also suggests that by losing just 10 percent of your total body weight, there will be a remarkable increase in life expectancy and your overall health. How long does it take to lose 10 pounds? Not very long at all if you consider the benefits.

If you eat green vegetables with all your meals, it will help you stay healthier for longer. Research on Alzheimers & dementia has proven that eating more leafy greens has been explicitly linked to lower rates of Alzheimers disease and other instances of brain aging (1).

The antioxidants that green leafy vegetables contain also does wonders for how your skin looks. This means that eating your greens regularly will not only help you retain your mental prowess, it will also ensure you look fresh, radiant, and youthful.

Ditch carb-rich breakfast options and fill up on eggs instead. Eggs are a great combatant against aging. Researchers at the University of Wisconsin discovered that lutein and zeaxanthin, both components of egg yolks, can keep macular degeneration at bay. This means that your eyes will remain clear and healthy as you age. Eggs are also a great food for weight loss and maintenance. Make sure yours are organic free-range eggs, which are the healthier choice!

While exposure to sunlight is important in order to get the requisite amounts of vitamin D, too much sun is not a good thing. Vitamin D is responsible for maintaining metabolism, mood and other important health aspects, but you should be careful about unnecessary exposure and invest in a good sunscreen.

Too much sun increases the risk of skin cancer, causes dark spots and wrinkles due to sun damage, all affecting your longevity and making you look years older than you are. Practice safe sun exposure by using sunscreen regularly and stop the aging process.

Ditch unhealthy packaged snacks and eat these super fruits instead. Bananas are an excellent source of potassium, which keeps your heart healthy and reduces muscle cramps. The resistant starch found in bananas leads to healthier gut bacteria, which decreases the risk of Alzheimers.

Resveratrol, a compound found in red grapes, helps keep off belly fatand is linked to improved circulation in the eyes which helps maintain your eyesight as you get older.Oranges, strawberries and kiwis are high in vitamin C which increases collagen production in your body. Collagen keeps cellulite and sagging at bay by increasing the firmness of your skin, making you look younger than ever.

Apricots contain beta-carotene, which lowers the risk of Alzheimers and other forms of cognitive decline.Blueberries help maintain youthful glow and the anthocyanin they contain significantly reduces the risk of dementia as you age.

Positive thinking can go a long way in your quest for anti-aging. Research published in the Journal of Personality and Social Psychology shows that people who reflected positively on their lives decreased their risk of death significantly. Additionally, focusing on the positives makes you happier and seem more youthful. Smiling makes you look younger.

Sitting all day speeds up the aging process, increases the risk of obesity and the risk of premature death. To keep your body healthy and youthful, make it a point to stay active. Go for a walk, swim, play with your kids or grandkids, do any activity as long as you get up and move about at least once every hour. Finally, a good nights sleep is the best way to stop the aging process.

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Anti-Aging Tips To Set The Clock Back 10 Years - Longevity LIVE - Longevity LIVE

There are lots of common misconceptions when it comes to the paleo diet. Often, people tend to view it as simply a high protein diet. However, the paleo diet is actually mostly plant-based. Its not a high protein diet either. Heres what you need to know

The paleo diet is a dietary plan that is heavily based on what humans might have consumed during the Palaeolithic era. Hence the name. Thistypically includes lean meats, fish, fruits, vegetables, nuts and seeds foods that in the past could be obtained by hunting and gathering.Importantly a paleo diet limits foods that became common when farming emerged about 10,000 years ago. These foods include dairy products, legumes and grains.

Thus, the majority of this diet is plant-based with most foods coming from what the gatherers would have been able to find. These foods include nuts, seeds, vegetables and fruits. Protein would have been eaten only when it was available and mostly in the form of lean meats or fish.

Its likely that some palaeolithic era humans followed what we would call a low-carb high-protein diet. But its just as likely that others will have eaten a high-carb low-protein diet. This diet, therefore, is a guideline and does not have to be the same for everyone. There are now several different versions of it. Some of these may include butter and even gluten-free grains such as rice.

Generally, however, according to Kris Gunnars of Healthline, these are the foods form the basic building blocks of a paleo diet:

Essentially, you want a diet full of whole, unprocessed foods. Try to choose the least processed option you can. Ideally, grass-fed, pasture-raised and organic. Other foods allowed in moderation include good qualityred wine as it is high in antioxidants or dark chocolate that has 70% or higher cocoa content.

Its all well and good to know what you can eat but what should you avoid if you want to move towards a paleo diet. According to Healthline, these are the foods you should be avoiding.

It may come across as a rather extreme way of eating, and it is. Youre essentially cutting out entire food groups from your diet. But the paleo diet does have quite a few benefits. One of the major benefits is of course weight loss. Its the extreme opposite to the current western diet which is packed full of processed foods. Instead, the paleo diet replaces processed foods with whole foods which are still packed full of nutrients.

Cutting out sugary foods and empty calories is definitely healthier and will ultimately lead to weight loss. According to a review in the American Journal of Clinical Nutrition, the paleo diet also has other major benefits. This includes lowering blood pressure, which ultimately reduces the risk of stroke, heart disease, heart attack and death.

And its not just the female celebs who have taken to paleo, Channing Tatum has tried it too. Voted the sexist man alive in 2012, its no surprise that Tatum has some tips and tricks up his sleeve to prepare for the big screen. Tatum went paleo to prepare for his role as an Olympic wrestler in Foxcatcher. Tatum explained that he ate mostly meat and vegetables during his preparation time but did allow himself to cheat on the weekends. Professional golfer Phil Mickelson, actress and comedian Aisha Tyler and even Matthew McConaughey are also reportedly followers of the paleo diet.

https://pubmed.ncbi.nlm.nih.gov/26269362/

https://www.everydayhealth.com/diet-nutrition/paleo-diet/what-are-risks-benefits-paleo-diet/

https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/paleo-diet/art-20111182

https://www.healthline.com/nutrition/paleo-diet-meal-plan-and-menu#TOC_TITLE_HDR_6

https://my.clevelandclinic.org/health/articles/17583-triglyceridesheart-health

https://www.everydayhealth.com/paleo-diet/diet/celebrities-who-have-tried-paleo-diet/

https://extratv.com/2016/06/23/blake-lively-on-her-body-transformation-for-the-shallows-and-her-obsession-with-harry-potter/

https://www.latimes.com/health/la-he-jessica-biel-5q-20170124-story.html

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The Paleo Diet: What is it really? - Longevity LIVE - Longevity LIVE

There's no silver bullet to living longer, says Dan Buettner, a National Geographic Fellow and journalist who studies the habits of people living in the "Blue Zones," which are the places in the world where people live the longest. The places are: Okinawa, Japan; Sardinia, Italy; Nicoya, Costa Rica; Ikaria, Greece, and Loma Linda, California.

But making small changes to your everyday routine from how you spend your lunch hour to whether you keep in touch with friends can make a big difference in the long run, Buettner tells CNBC Make It.

Especially during the Covid pandemic, as most people's lives have been dramatically changed, here are the top three habits from the Blue Zones that Buettner says are important to start now.

Famous research from Harvard has shown that people who have close relationships live longer than those who are isolated.

"If you're socially disconnected, [or] if you don't have three friends you can count on on a bad day, it shaves about eight years off your life expectancy, compared to somebody who's well connected," Buettner says.

During the pandemic, even video calls can have a positive effect: "If the conversation has emotional content to it, it counts," he says.

"In the pre-Covid days, we would take a lunch break and often go eat with a colleague," he says. Since that's not possible for many people during the pandemic, he suggests a mid-day video call with someone you care about. "Make that part of your daily routine," he says.

Lots of research supports that exercising wards off your risk of disease and death, but you don't need an exercise bike or home gym to reap the benefits.

"People in Blue Zones walk every day and they make it to 100 without all the other gadgetry and pageantry of working out," Buettner says.

People who commute to work and have to walk to a bus or train station have a lower risk of developing cardiovascular issues. If you're working remotely and are more sedentary than usual, take walks around the block that mimic your morning and evening commutes, Buettner says. Leave your sneakers or walking shoes by the front door "to constantly remind you to use them," he says.

Going on walks during the pandemic is an easy way to exercise safely outdoors and also to socialize with someone from outside of your household. Dr. Anthony Fauci has said he powerwalks 3.5 miles a day to de-stress after work.

Studies have shown that walking boosts your creativity, improves your memory and even helps you sleep.

Taking short mid-afternoon naps is common in many of the Blue Zones regions, Buettner says.

"People who report napping at least 20 minutes, five days a week, have about a third lower rate of heart disease than people who just motor through the day," he says.

After a nap, you typically feel sharper and have lower levels of the stress hormone cortisol, Buettner says. Over time, regular nappers also have less inflammation in their bodies, he adds. (Chronic inflammation is associated with several diseases.)

The key to avoiding grogginess is to only nap for 20 minutes, according to the National Sleep Foundation.If you're working from home, squeeze in a power nap during your lunch break it could improve your performance. Studies suggest that short power naps can increase job performance by up to 34% and improve alertness by 54%.

Check out:How the pandemic killed your motivation, and 6 simple ways to get it back, according to science

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3 easy habits of the worlds longest-living people that can keep you happy and healthy during the pandemic - CNBC

On Thursday, the French nun Sister Andr turned 117 and celebrated with an exceptional feast. A first course of foie gras set the tone for capon with fragrant mushrooms, and was washed down with a hearty glass of red wine.

David Tavella, the communications manager for Andrs care home in Toulon, told the Associated Press that red wine is one of Andrs secrets to longevity. Across the table, red wine, Champagne, and port flowed as Andrs friends toasted in her honor.

The meal concluded a few hours later with Sister Andrs favorite dessert, Baked Alaska. It followed a mass in her honor, led by the local Catholic bishop, and a video call with her great, and great-great, nephews.

At this point, Sister Andr is in line to become the worlds oldest living person. Shes currently Europes oldest and the worlds second oldest, right behind Kane Tanaka, who turned 118 last January.

When asked how shell celebrate her next birthday, Andr replied, I wont be here next year. But dont be perturbed, shes repeated the phrase every birthday for the last ten years, so winemakers better start setting aside their best reds for the next feast.

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117 Year Old French Nun Links Red Wine to Her Longevity - VinePair

When it comes to living a long and healthy life, so much emphasis is put on ones diet. Another factor which can contribute positively to an increased lifespan includes owning a dog. From improving mental health to helping with cardiovascular health, being a dog owner could help boost your longevity. How?

Owning a dog and taking it out for daily walks, acts as a social catalyst for a person.

It helps to promote social connections, conversations and can lead to the development of networks of support.

The connectivity of pets helps a person also feel safer and more loved in their own home.

Owning a dog and getting outdoors more often becomes common practice.

A wealth of research indicates that escaping to a neighbourhood park can lower a person's stress levels, decrease blood pressure and reducetherisk of asthma, allergies, diabetes and cardiovascular disease, whileboostingmental health and increasinglife expectancy.

In another study published in the journal Scientific Reports, spending at least 120 minutes outdoors each week can have a major positive effect on life expectancy and overall health.

The study examined data from nearly 20,000 people in Englandfrom 2014 to 2016, which asked them to record their activities within the past week.

It found that people who spent two hours a week or more outdoors reported being in better health and having a greater sense of well-being than people who didnt get out at all.

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How to live longer: A dog helps improve heart health & manages stress to boost longevity - Express

Virtual Tasting with Phil Long of Longevity Wines Categories: Culture and Heritage, Beer, Wine, & Spirits Visit Their Website Pricing info: $30

Ticket Info: https://thewinefeed.com/products/virtual-tasting-with-phil-long-of-longevity-wines

We are thrilled to share two of his wines with you as well as a Q&A session hosted by Angela Thorpe and Taryn Scarborough.

Angela Thorpe works as a public historian by day, amplifying stories around Black history and culture across North Carolina. By night, she is an emerging wine educator with a passion for exploring and sharing how Black people have contributed to the U.S. wine industry over time. She earned her WSET Level 1 in 2020. Her favorite wine is Spanish Tempranillo.

Taryn Scarborough is a Raleigh, NC native who earned her WSET Level 1 in 2019. She has a passion for educating and sharing her joy of wine with others. Taryn works as a project manager in the clinical research industry and loves to travel (pre-COVID) in her spare time. Favorite wine varietal: Sauvignon Blanc

This event is virtual and will be conducted live over Zoom as well as recorded so that participants may revisit the event. Each signup includes 2 full bottles of wine. We hope you will join us!

2019 Longevity - Chardonnay

2018 Longevity - Cabernet Sauvignon

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Virtual Tasting with Phil Long of Longevity Wines :: Shopping & Retail in North Carolina :: Out and About at WRAL.com - WRAL.com

Winda Wilson celebrated her milestone birthday with a spa day at her senior living facility.

HOUSTON This week Wilda Wilson got a surprise for the ages.

On her 105th birthday, she received a surprise spa day.

Ms. Wilda is an inspiration to all of us," said Abraham Mathew, executive director ofParkway Place.

Wilson's family says Wilda is a doer.

She's been getting things done since 1916. That's when she was born on a farm in Kansas. At that time in history, a brand new Model-T cost a whopping $306 and it was only 22 cents a gallon to fill up.

And if you didn't know, the hamburger bun was invented that year.

A lot has changed over the years.

For decades Wilda was a hairdresser and salon owner. But on this special day, Wilson would be the one in the chair being pampered, getting a scalp massage, styling and a manicure.

"Im glad we could bring a smile to her face today, said Mathew.

Masks were the must-have accessory for Wilson's party, but it didn't cover anyone's happiness. Especially not Wilda's on her big day.

Wilson credits her daily breakfast of five extra crispy pieces of bacon and two pieces of toast smothered in jam to her long life.

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'An inspiration to all of us': Houston woman turns 105, credits bacon and toast to her longevity - KHOU.com

SportFootballHibsDarren McGregor has long since passed the accepted expiration date on a football career.

Saturday, 13th February 2021, 7:00 am

But, having decided to spice things up, the 35 year-old has proved himself unwilling to be constrained by such arbitrary limitations.

The Hibs defender has had to bide his time this season, regularly restricted to one of the substitute slots as others made the starting berths their own. He managed a few League Cup games as those ahead of him in the pecking order were called away on international duty, but it is only in recent weeks that he has been given the chance to impress on league duty. He has not squandered the opportunity.

He lists several factors but, possibly surprisingly, focuses on the medicinal benefits of turmeric.

It was specifically under Neil Lennon and my knee was giving me all sorts of bother. It was a dull ache and Id tried taking injections or spending a day in and a day out. I dont take any anti-inflammatories but I was advised to take turmeric by the sports science team. Its proven to help with inflammation in your joints. I take them in concentrated form like a tablet and Nathan Ring [physio and Hibs Head of Sports Medicine] has devised a plan along with Colin Clancy, the strength and conditioning coach, which has helped me.

This has maybe been 12-18 months of meticulous work in the background. Trying things and if they dont work trying something else. Now I feel amazing, Im in a sweet spot and I would just like to keep it going.

But, as well addressing his physical predicament, as a team player and mentor, he has also had to consider the bigger picture as he waited to break back into the side.

You have to park your ego and accept that the guys who are playing ahead of you deserve to be in the team. The back three before I came in were doing tremendous and I had to wait for my time.

The gaffer decided to put me in and I think I have taken the opportunity but that is because of a lot of hard work that has been done in the background when no-one was really paying attention. That was in the off chance that I would get an opportunity and I think that has helped me to fit in seamlessly.

The endeavours behind the scenes comprise more than just time on the training pitch or in the gym, it is a lifestyle choice and a willingness to embrace any ideas that could squeeze a bit more out of a body he acknowledges is not getting any younger but remains capable of facilitating his playing ambitions.

Coming into the team for the Rangers game that commanding performance at the heart of the backline, helped the team regain its footing after the Betfred Cup semi-final slip. Retaining his place, he has been part of a winning team ever since.

The Leith side had been heading to Ross County in search of a fourth successive win before a frozen pitch saw that match postponed.

But last weeks important victory over Aberdeen means that they will hold onto third place regardless of results elsewhere. And McGregors strong defensive displays and leadership qualities have contributed to that.

But he admits it wasnt so long ago that he feared time was running out for him and while he concedes that he now treats every game as though it could be his last, he says the turmeric has given him a new lease of life.

You are aware that the clock is ticking and your career is winding down but I can only speak for my own personal feelings and how my body feels. There were times in seasons gone by when i was training some days and not training others just so my body could recover but, this season, touch wood, I have trained every single day and done everything asked of me in the gym.

I just need to keep doing what I'm doing every day and see how long I can go.

As a football player growing up I think you think of 30 as this dreaded age but I think it is definitely changing. Paul Hanlon is 31 now; Paul McGinn is 30.

That gives a combined age of 96 for a back three who have managed two clean sheets in the past three games.

Now, 30 is young. People that dont play the game that are the same age as me, who I maybe went to school with and havent looked after themselves the way I have or done the training Ive done, they maybe put themselves in my shoes and think that at 35 Im definitely past it. But people forget the amount of work we do when we come in here and how meticulous we are with diet etc.

Footballers are definitely getting fitter. Maybe 30-40 years ago, 30 was the age of retirement but I can only be honest. I am training every day and Im sure a lot of the guys will say I do well in training, although some might say I just kick people, and I feel good coming in every day. I still enjoy it.

I'm not at a point when I get up every morning and my body is that sore that I'm thinking I can't be bothered going in. I am appreciating that I am in a hugely privileged position and I want to stay in this position for as long as I can so I am willing to sacrifice whatever needs to be sacrificed for me to keep it going and keep playing for Hibs.

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Hibs defender Darren McGregor reveals the surprising secret behind his longevity and explains why he is not ready to fade into retirement - The...

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PARIS Question: How does one cram enough candles onto a birthday cake for one of the world's oldest survivors of COVID-19? Answer: With 117 candles, you can't.

A French nun who is believed to be the world's second-oldest person celebrated her 117th birthday in style on Thursday, with multiple treats and well-wishes, cards and flowers to fete her exceptional longevity through two world wars and a recent coronavirus infection.

Sister Andr also got a Mass in her honor and a feast with Champagne, red wine and port. Then came a nap followed by more festivities, including an afternoon snack of baked Alaska, her favorite dessert.

"It made me very, very, very, very happy," the birthday girl said. "Because I met all those I love and I thank the heavens for giving them to me. I thank God for the trouble they went to."

Sister Andr's big day got rolling with a morning video call with her great-nephews and great-great nephews, followed by a Mass in her honor led by the local Catholic bishop, said David Tavella, the communications manager for the care home in the southern French city of Toulon where the nun lives.

Her birthday feast included a starter of foie gras, followed by capon with fragrant mushrooms. "All of it washed down with red wine, because she drinks red wine. It's one of her secrets of longevity," Tavella told The Associated Press. There was also port and Champagne "because 117 years have to be toasted," he said.

She skipped dessert because she was tired, but got it served to her later after a nap with three candles and the numerals 117 on top.

Packing on 117 candles would have been impossible.

"We stopped trying a long time ago," Tavella said. "Even if we made big cakes, I'm not sure that she would have enough breath to blow them all out. You would need a fire extinguisher."

Sister Andr's birth name is Lucile Randon. The Gerontology Research Group, which validates details of people thought to be 110 or older, lists her as the second-oldest known living person in the world, behind only an 118-year-old woman in Japan, Kane Tanaka.

Tavella told French media earlier this week that Sister Andr tested positive for the coronavirus in mid-January but she had so few symptoms that she didn't even realize she was infected. Her survival made headlines both in France and beyond.

"When the whole world suddenly started talking about this story, I understood that Sister Andr was a bit like an Olympic flame on a 'round the world tour that people want to grab hold of, because we all need a bit of hope at the moment," Tavella said.

When Tavella talked to her Thursday about celebrating her next birthday in 2022, she replied: "I won't be here next year," he quoted her as saying, adding: "But she has been saying that for 10 years."

By strange coincidence, Tavella celebrated his 43rd birthday on Thursday.

"We often joke that she and I were born on the same day," he said. "I never tell myself that she is 117 because she is so easy to talk to, regardless of age. It is only when she talks about World War I as though she lived through it that I realize, 'Yes, she did live through it!'"

Originally posted here:
COVID-defying nun toasts 117th birthday with wine and prayer - The Topeka Capital-Journal

Global Longevity and Anti-senescence Therapy Market Trends and Forecast

The global longevity and anti-senescence therapies market should grow from $329.8 million in 2018 to $644.4 million by 2023 with a compound annual growth rate (CAGR) of 14.3% during 2018-2023.

Report Scope:

The scope of this report is broad and covers various therapies currently under trials in the global longevity and anti-senescence therapy market. The market estimation has been performed with consideration for revenue generation in the forecast years 2018-2023 after the expected availability of products in the market by 2023.

The global longevity and anti-senescence therapy market has been segmented by the following therapies: Senolytic drug therapy, Gene therapy, Immunotherapy and Other therapies which includes stem cell-based therapies,.

Revenue forecasts from 2028 to 2023 are given for each therapy and application, with estimated values derived from the expected revenue generation in the first year of launch.

The report also includes a discussion of the major players performing research or the potential players across each regional longevity and anti-senescence therapy market. Further, it explains the major drivers and regional dynamics of the global longevity and anti-senescence therapy market and current trends within the industry.

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The report concludes with a special focus on the vendor landscape and includes detailed profiles of the major vendors and potential entrants in the global longevity and anti-senescence therapy market.

- 71 data tables and 40 additional tables- An overview of the global longevity and anti-senescence therapy market- Analyses of global market trends, with data from 2017 and 2018, and projections of compound annual growth rates (CAGRs) through 2023- Country specific data and analysis for the United States, Canada, Japan, China, India, U.K., France, Germany, Spain, Australia, Middle East and Africa- Detailed description of various anti-senescence therapies, such as senolytic drug therapy, gene therapy, immunotherapy and other stem cell therapies, and their influence in slowing down aging or reverse aging process- Coverage of various therapeutic drugs, devices and technologies and information on compounds used for the development of anti-ageing therapeutics- A look at the clinical trials and expected launch of anti-senescence products- Detailed profiles of the market leading companies and potential entrants in the global longevity and anti-senescence therapy market, including AgeX Therapeutics, CohBar Inc., PowerVision Inc., T.A. Sciences and Unity Biotechnology

Summary

Global longevity and anti-senescence therapy market deals in the adoption of different therapies and treatment options used to extend human longevity and lifespan. Human longevity is typically used to describe the length of an individuals lifetime and is sometimes used as a synonym for life expectancy in the demography.

Anti-senescence is the process by which cells stop dividing irreversibly and enter a stage of permanent growth arrest, eliminating cell death. Anti-senescence therapy is used in the treatment of senescence induced through unrepaired DNA damage or other cellular stresses.

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Global longevity and anti-senescence market will witness rapid growth over the forecast period (2018-2023) owing to an increasing emphasis on Stem Cell Research and an increasing demand for cell-based assays in research and development.

An increasing geriatric population across the globe and a rising awareness of antiaging products among generation Y and later generations are the major factors expected to promote the growth of global longevity and anti-senescence market. Factors such as a surging level of disposable income and increasing advancements in anti-senescence technologies are also providing traction to the global longevity and anti-senescence market growth over the forecast period (2018-2023).

According to the National Institutes of Health (NIH), the total geriatric population across the globe in 2016 was over REDACTED. By 2022, the global geriatric population (65 years and above) is anticipated to reach over REDACTED.

An increasing geriatric population across the globe will generate huge growth prospectus to the market.

Senolytics, placenta stem cells and blood transfusions are some of the hot technologies picking up pace in the longevity and anti-anti-senescence market. Companies and start-ups across the globe such as Unity Biotechnology, Human Longevity Inc., Calico Life Sciences, Acorda Therapeutics,.

are working extensively in this field for the extension of human longevity by focusing on study of genomics, microbiome, bioinformatics and stem cell therapies,. These factors are poised to drive market growth over the forecast period.

Global longevity and anti-senescence market is projected to rise at a CAGR of REDACTED during the forecast period of 2018 through 2023. In 2023, total revenues are expected to reach REDACTED, registering REDACTED in growth from REDACTED in 2018.

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The report provides analysis based on each market segment including therapies and application. The therapies segment is further sub-segmented into Senolytic drug therapy, Gene therapy, Immunotherapy and Others.

Senolytic drug therapy held the largest market revenue share of REDACTED in 2017. By 2023, total revenue from senolytic drug therapy is expected to reach REDACTED.

Gene therapy segment is estimated to rise at the highest CAGR of REDACTED till 2023. The fastest growth of the gene therapy segment is due to the Large investments in genomics.

For Instance; The National Human Genome Research Institute (U.S.) had a budget grant of REDACTED for REDACTED research projects in 2015, thus increasing funding to REDACTED for approximately REDACTED projects in 2016.

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Global Longevity and Anti-senescence Therapy Market Trends and Forecast interpreted by a new report - WhaTech

Jack and Rose, Allie and Noah, Johnny and Baby, Sandy and Danny these are just some of the most iconic movie couples that spring to mind when we think of L-O-V-E.

For us romantics, its a brief snapshot of a couples unwavering passion for each other that we can escape in for an hour or two (whether thats proving their love by building a house, ensuring nobody puts their beloved in the corner, or letting the other hog the door so they could survive a treacherous icy ocean).

But heres the thing; theres more to relationships than the honeymoon period. And none of our favourite romantic films ever seem to show those uneventful days that come later. You know, like the ones weve endured ourselves in lockdown purgatory, as we constantly ask our partner how their day was, despite fully knowing that it was, quite literally, the same as yesterday.

But no matter how unrealistic we know it is, we cant help but fall back on those same tried-and-tested romcoms.

They play to our longings and desires for connection, says psychologist, author and founder of The Village, Dr Kalanit Ben-Ari.

They are also something we can all relate to so many people are in love with the idea of a romantic relationship. When we are touched by a scenario in a film, we are actually in touch with a part in ourselves. It could be our dreams and longing or fears and losses, which might be in our awareness or unconsciously.

Hoping for a happily ever after certainly isnt a bad thing, but I know my own favourite on-screen couples have skewed my own expectations of love and not exactly in a healthy way.

Im not alone in this, either; as Dr Ben-Ari says: Even though a film can generate feelings of positivity, some might experience an after-effect depending on whats going on in their own life.

For example, a couple at the start of a relationship might be left feeling incredibly positive, whereas couples in an uncertain stage of their relationship might feel a sense of longing and sadness for the disparity between the films story and their reality.

Working closely with Dr Ben-Ari, then, I decided to take a look back at some of those iconic Hollywood couples who many perceive to be epic examples of love.

Some definitely stand the test of time. Others, on closer inspection, have some issues.

Jack and Rose, Titanic

Those of us who have seen Titanic enough times will argue there was space for Jack on that floating door. Which means he sacrificed himself unnecessarily for a holiday romance that had lasted just two days.

Thats right; from the very moment that Jack saved Rose from jumping off the Titanic to the moment he freezes in the Atlantic Ocean, only a little over 48 hours has passed. Anyone else think it was already over for Rose?

Longevity rating: 1/5

Johnny and Baby, Dirty Dancing

Johnny and Baby are from different walks of life who find themselves in the same place at the right time in Dirty Dancing. But, with a considerable age gap between them (and not much in common other than their dancing skills), its likely this love was never built to last outside of Kellermans.

Longevity rating: 2/5

Sandy and Danny, Grease

Shes the ultimate good girl, and hes the bad boy who just wants to get friendly down in the sand. Essentially, Sandy and Danny are complete polar opposites who spend the entire film trying to awkwardly impress each other and their peers.

These typical narratives often carry a deeper meaning to what we see on the surface, says Dr Ben-Ari.

There are unconscious processes or agendas that cause opposites to attract for example, and those who are being pursued might not show any interest as a form of defence mechanism from past pain.

Longevity rating: 2/5

Annette and Sebastian, Cruel Intentions

Yes, its another good girl/bad boy trope.

In Cruel Intentions, Sebastian makes a bet with his scheming stepsister Katherine and winds up falling truly in love with his pure-as-a-dove prey, Annette. When his toxic masculinity finally gives way to vulnerability, though, its too late and we wind up speeding towards the films tragic conclusion.

Longevity rating: 2/5

Josh and Cher, Clueless

Clueless is a full-on Monet: it all looks great from far away but up close-up its a mess. Personally, I swoon over any film with the ageless Paul Rudd, but when Chers true love ends up being his character her eye-rolling, nit-picking stepbrother, Josh it really is a case of as if!

Longevity rating: 2/5

Allie and Noah, The Notebook

Communication is a big deal in a relationship; if you dont tell the other what youre thinking or how youre feeling, then how on earth are they supposed to know?

Noah and Allies short-lived summer romance (which begins, as youll no doubt remember, with him blackmailing her into dating him) is heartbreakingly dragged out through the course of their entire lives, and all because neither of them could be bothered to sit down and have a proper conversation.

Longevity rating: 3/5

Lara Jean and PeterKavinsky, To All the Boys Ive Loved Before

Shes the sweet outsider, hes the cute popular jock: its a familiar story. Unlike Grease and The Notebook, though, these two dont just take the time to get to know one another; they make sure they share the same core moral values, too.

Better still? Even in these modern social media times, its an adorable love letter from Lara Jean to Peter Kavinsky that brings them together. Perfection.

Longevity rating: 4/5

Rosemary and Dill, Easy A

Stanley Tucci and Patricia Clarkson play parents Rosemary and Dill in the classic 2010 film Easy A. They are, quite literally, the backbone of this delightful tale, and they show that mature love can be fun, caring and passionate even while dealing with their daughter Olives slut-shaming drama.

Longevity rating: 5/5

Monica and Quincy, Love And Basketball

Love And Basketball is a cult classic, with childhood sweethearts Monica and Quincy sharing an everlasting bond over the sport. A friendship turns into real love. And, yes, they make some mistakes along the way before finding the right time to be together.

But, as director Gina Prince-Bythewood explains to Shadow And Act about the films iconic sex scene, the whole thing is hinged on the couplds respect for one another.

When we did it, I was very specific about what I wanted it to be, she said. Its a girls first time, Monicas first time, I wanted it to be the fantasyI kind of wanted to give a blueprint for boys and girls of what to expect. I wanted the reality of it. Sanaa [Lathan] and Omar [Epps] were so dope in that scene, so protective of each other. They just gave the realness, especially just the looks that they were giving each other that said so much, which added organic humor to it which I loved.

Lets just ignore that he was two weeks away from the wedding when Monica finally made her move, yeah?

Longevity rating: 4/5

Jim and Michelle, American Pie

Jim loses his virginity to Michelle after prom. She isnt the porn star of his dreams, but shes quirky, and human, and believable. And, while they may seem mismatched, theyre destined to make it down the altar. Band geek and goofball for the win!

Longevity rating: 5/5

Sarah and Derek, Save The Last Dance

When white ballet dancer Sarah ends up at a majority-Black high school, she meets Derek. The interracial couple go against the grain, much to the distaste of his friends and family, but cringeworthy hip hop dancing scenes aside (Lets put that S-E-X in those H-I-P-S) they support each others dreams 100% and find love together.

Longevity rating: 4/5

Erin and Garrett, Going The Distance

This film made me believe that, if you really love someone, you will spend hours talking on the phone to keep that long distance relationship going. Im here, fresh from heartbreak, to tell you that isnt the case. Going The Distance deals with the idea that you cant physically touch someone else for months on end. And, while Erin and Garrett nearly dont make it, after a time jump, a sensible cooling-off period, and a decision to relocate, true love wins.

Longevity rating: 4.5/5

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Best film couples & movie relationships, according to a therapist - Stylist Magazine

Former India batsman, VVS Laxman reveals that he was impressed by Ishant Sharmas will to bowl long spells when he first met the pacer. Laxman lavishes praises on the hard work the Ishant has done since making his debut in 2007 to pick 300 Test match wickets.

On Monday, in Chennai, against England with the wicket of Dan Lawrence, Ishant became the 6th Indian bowler and only the third Indian pacer after Kapil Dev and Zaheer Khan to bag 300 Test wickets.

The lanky seamer has had a career marred with injuries, however, illustrious with some scintillating spells over the years as he reached this feat in his 98th Test. It is often talked about how captains, in domestic cricket and for the national team, have a liking for Ishant because of his endurance to bowl longer spells.

When I was tweeting about his 300th wicket, I remembered the debut Test match of Ishant in 2007 against Bangladesh. A tall, lanky fast-bowler. We all knew he had the talent to do well for India. But the amount of hard work he exhibited throughout his career.

There was Zaheer and other talented fast bowlers like RP Singh, Sreesanth, or Irfan Pathan, but here was one fast bowler who was ready and prepared to bowl 20 overs every day not every innings but every day. Theres a reason why he has had this longevity, VVS Laxman told Star Sports.

VVS Laxman observed that Ishant has a better wrist position and is bowling more fuller lengths than he used to prior to the time spend with former Australia pacer, Jason Gillespie. After remaining unsold in the IPL auction, Ishant went to England to play county cricket for Sussex in 2018 where he was coached by Gillespie.

VVS Laxman reckons the senior India pacer returned a much better and improved bowler from his stint in the county. And rightly so; since the start of 2018, he has picked 74 wickets in 19 Tests at an average of 19.39; compared to the average of 36.55 in his previous 79 Tests.

What changed since 2018, is his wrist position. He is a very hard-working bowler, always looking to improve. He went to Sussex, worked with Jason Gillespie, played in the country championship, and was working on his seam position. And this is what he got right. Since then, he is pitching the ball up and he is ending up getting more wickets, Laxman added.

Also Read: Had Kuldeep Yadav Played For Some Other Country, He Would Have Taken 200 Wickets And Played 50 Tests By Now, Says His Coach Kapil Pandey

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Ishant Sharma Was Prepared To Bowl 20 Overs A Day, That's The Reason For His Longevity - VVS Laxman - Cricket Addictor

YORBA LINDA, Calif., Feb. 8, 2021 /PRNewswire/ -- Dental professionals have long sought improvements in dental implant bridge stability, longevity, and esthetics. NobelProcera Zirconia Implant Bridge is a premium solution that provides individualized, high-end, implant-based restorations and services that seek to improve patient outcomes, esthetics, and implant longevity.

"Precision is a key feature for positive patient outcomes and implant longevity. The NobelProcera Zirconia Implant Bridge is cement-free, manufactured with high-strength material and is an excellent choice," said Prof. Dr. Markus B. Blatz from Philadelphia, Pennsylvania.

Made for estheticsAvailable in 10 precisely matched VITA shades, the NobelProcera Zirconia Implant Bridge is designed with esthetics in mind. It was designed for a smaller, angulated screw channel, with the new Omnigrip Mini Screwdriver to improve occlusal esthetics.

With the recent partnership with DOCERAM Medical Ceramics, the zirconia implant bridges are produced with the high-end Nacera Pearl zirconia material, which meets Nobel Biocare's highest quality standards.

Complete design flexibilityThe new offering is available in full-contour, cut-back, thimble, and framework styles (with or without soft tissue), making it possible to achieve natural looking restorations. The combination of the angulated multi-unit abutment and angulated screw channel provides up to 55 degrees of restorative freedom.

Cement-freeRemoving cement from the equation saves time and simplifies the process of implant bridge procedures.

High precision and material strengthNobelProcera works to achieve the goals of improved stability, durability, and esthetics through a manufacturing process that prioritizes high material strength and superior precision.

NobelProcera Zirconia Implant Bridge is now available in DTX Studio Lab and 3Shape systems.

_________________________Nobel Biocare is a world leader in the field of innovative implant-based dental restorations. The company's portfolio offers solutions from single tooth to fully edentulous indications with dental implant systems (including key brands NobelActive and NobelParallel), a comprehensive range of high-precision individualized prosthetics and CAD/CAM systems (NobelProcera), digital solutions for treatment planning (DTX Studio suite) and guided surgery, as well as biomaterials (creos regenerative solutions). Nobel Biocare supports its customers through all phases of professional development, offering world-class training and education along with practice support and patient information materials.

View original content to download multimedia:http://www.prnewswire.com/news-releases/the-new-nobelprocera-zirconia-implant-bridge-simplifies-the-partnership-between-clinicians-and-technicians-301223356.html

SOURCE Nobel Biocare Usa, Inc.

Company Codes: Swiss:NOBN

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The new NobelProcera Zirconia Implant Bridge simplifies the partnership between clinicians and technicians - BioSpace

For centuries many have searched for the secret to a longer life. From not smoking to reducing alcohol intake, there are many ways to help lengthen ones life. Drinking more tea is another healthy approach and in particular Rooibos tea which helps reduce cancer risk, promote healthy hearts and weight loss and boosting longevity.

Rooibos teas health benefits include supporting a healthy heart, preventing cancer, managing and preventing diabetes, supporting healthy digestion, fighting inflammation, promoting stronger bones, supporting weight loss, slowing down ageing process, treating blood pressure, supporting healthy skin, fighting dandruff and supporting kidney health.

The College of Korean medicine conducted a study and found that Rooibos tea has a positive effect on heart health as it helps keep hormone levels balanced and inhibits the release of excessive hormones from the adrenal gland.

This further helps to prevent hypertension and high blood pressure.

Rooibos tea contains nothofagin and aspalathin, which are powerful chemical compounds known to calm inflammation in the vascular system and acts as a vasodilator.

READ MORE-Apple cider vinegar cleaning hacks: 10 household uses for ACV

Rooibos is associated with health benefits due to its high levels of health-promoting antioxidants, which include aspalathin and quercetin.

Antioxidants may help protect cells from damage by free radicals.

In a study published in the US National Library of Medicine National Institutes of Health, free radicals, antioxidants and how it helps with overall health was investigated.

The study noted: When an overload of free radicals cannot gradually be destroyed, their accumulation in the body generates a phenomenon called oxidative stress.

This process plays a major part in the development of chronic and degenerative illness such as cancer, autoimmune disorders, aging, cataract, rheumatoid arthritis, cardiovascular and neurodegenerative diseases.

The human body has several mechanisms to counteract oxidative stress by producing antioxidants, which are either naturally produced in situ, or externally supplied through foods and/or supplements.

Tea chemist and scientist Dr Tim Bond said: There is also evidence to show that rooibos helps protect body cells from oxidative damage.

The explanation for these effects is that rooibos tea contains a diverse range of phenolics including two unique polyphenols, aspalathin and nothofagin, which have a particularly strong anti-oxidative activity.

Rooibos tea also contains essential bone strengthening minerals including potassium, calcium and magnesium all integral for proper bone health.

Rooibos tea could also help to reduce the likelihood of brain function decline.

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How to live longer: Rooibos tea prevents cancer and promotes healthy hearts - Express

Whats the secret to living a healthy, long life? It was the big question on Daniel Kennedys mind when he set out to direct and produce his (aptly named) docu-series, Healthy Long Life. Besides wanting to know to inform his own personal habits, he had a stake in finding the answer for professional reasons too: As the CEO of Oasis of Hope Hospital in Tijuana, Mexico, helping people live well into old age is one of his great missions.

Kennedy decided to travel all over the world (this was pre-pandemic) to see if he could find the answer by learning from the worlds leading longevity experts. I was interested in going to the longevity capitals of the world, Kennedy says. Of course the research on Blue Zones caught my attention, but there are many other places where [living to be over 100 in good health] is common so I wanted to go other places too.

As of January 2020, life expectancy in the U.S. was 78.7 years, and is projected to increase to 85.6 by the year 2060 (although the ongoing coronavirus pandemic may affect that estimate). We have modern medicine to thank for this, but what modern medicine has failed to do is add more healthy years to life, Kennedy says. We are living longer because we are able to overcome infections and treat disease, but what modern medicine doesnt do as well is prevent disease. With that in mind, Kennedy says he wanted to learn from cultures outside the U.S. that value other healing traditions.

While he did visit a few Blue Zones regionsspecifically Sardinia, Italy and Okinawa, Japanhe traveled far and wide to unsung longevity hotspots too. So, did he discover the secret to living a healthy, long life? Kennedy says he definitely came back from the trip wiser. Here are some highlights of what he learned about longevity from five different countries around the globe.

Kennedy traveled to India to learn more about Ayurveda, a holistic medicine practice that has been around for over 5,000 years, and its potential to increase longevity. He spoke with some of the countrys leading health experts, including non-invasive cardiology pioneer Bimal Chhajer, MD, and spice expert Deepa Krishnan, to learn about how Ayurvedic principles play primary roles in many Indian peoples lives.

Traditionally, Ayurvedic practices are used to bring balance to the body based on each persons individual dosha (their emotional and physical constitution). Ayurvedic physicians and healers use your dosha to help identify, customize, and prescribe lifestyle changes and remedies that aim to balance your energies, prevent disease, and preserve health. In this way, doshas are used to personalize medicine. For example, a pitta dosha is linked to premature aging more than those with a kapha dosha. Ayurvedic healers in India use information like this to inform their health advice.

Kennedy also experienced the benefits first-hand of the pungent spices so prominent in Indian food (and in many cases, important to Ayurvedic remedies). Turmeric, ginger, nutmeg, and saffron, are just a few of the common spices used in Indian cooking that are linked to lowering inflammation, the root cause of chronic diseases and cognitive decline. In this way, what you eat can be directly tied to disease prevention and living a longer, healthy life.

What I learned from Dr. Chahhajer is how food is being used to promote healing, Kennedy says. He also works with patients in areas of anger management, forgiveness, and stress management. All of these ways, he says, inspire more balance, which he believes is essential to longevity.

Watch the video below to learn more about how turmeric is good for longevity:

Since Kennedy is the CEO of a hospital in Mexico (and he himself has Mexican roots), he decided to see what he could learn in his own country, too. In Mexico, he spoke with Mayan shaman Bartolome Poot Nahuat, Pedro Batiz, the co-founder of Divine Flavor, and various centenarians about their lives and practices.

Like in India, Kennedy says living a life of balance was something the experts he encountered spoke of, even if they didnt use Ayurvedic principles to inspire it. Kennedy says what he learned in Mexico was to be present. [Many of the people I met] dont focus on yesterday or tomorrow, they focus on today, he says. For many, being part of a close-knit extended family and community are key; life is lived together, not alone. To this point, a2019 United Nations report found that living with a child or extended family members was the most common living arrangement for elderly adults in Latin America.

Like Indian cuisine, Mexican cuisine traditionally uses lots of health-promoting spices. Cayenne pepper, garlic, cilantro, chipotle powder, and cinnamon are all common spices in Mexican cuisine that are linked to warding off chronic disease by lowering inflammation.

Watch the video below to learn more about the health benefits of garlic:

When you look at Israel on a map, its right in the middle between Africa, Asia, and Europe, so all the traders from these regions crossed through Israel and brought their healing traditions along, Kennedy says. Because of this, Israel is really a melting pot of wisdom from all three of these continents.

Kennedy says the biggest longevity lesson he learned from Israel was using food as medicine. (Yep, food, once again!) The food in Israel is so incredibly fresh. Fresh vegetables, fruit, and fish are a huge part of the culture. He learned first-hand about the longevity-boosting properties of the Mediterranean diet from experts including Ronit Endevelt, Ph.D., the director of the nutrition division for the Israeli Ministry of Health & School of Public Health and Haifa University, Ayala Noy Meir (a professional olive oil taster), and Uzieli Hazay, who runs the Etrogman juice bar in Tel-Aviv that sells many natural remedies.

Hundreds of studies have linked the Mediterranean dietwhich advocates for lean proteins, whole grains, seafood, and plenty of vegetablesto longevity. There have been studies upon studies that have shown that the Mediterranean diet can lower the incidence of heart disease by as much as 70 percent, Suzanne Steinbaum, DO, a cardiologist and the director of womens cardiovascular prevention, health, and wellness at Mount Sinai Hospital in New York City, previously told Well+Good. Its why the eating style popular in Israel (and other parts of the Mediterranean) is so often recommended by doctors here in the U.S.

Watch the video below to learn more about why the Mediterranean diet is linked to longevity:

The infamous China Study, one ofthe largest comprehensive studies of human nutrition ever conducted, is what drew Kennedy to China. The study, which collected data from 6,500 adults in 65 prefectures in China over the course of 20 years, was a partnership between Cornell University, Oxford University, and the Chinese Academy of Preventative Medicine. Kennedy spoke directly with lead researcher T. Colin Campbell, PhD, who wrote the book The China Study($15) to learn more about its findings.

Once again, Kennedy says one of the biggest lessons he learned was through food. Dr. Campbell shared with him that one of the major takeaways of the China Study is how plant-based eating can protect against chronic diseases, including cancer and heart disease. I saw first-hand what plant-based eating looks like in China by visiting the market, Kennedy says. I was amazed at the incredibly vast variety of vegetables there were. In the U.S., you might find three or four different types of apples and a few different types of mushrooms, but in China, I had seven different mushrooms in one meal and they have many more different types of apples. I saw carrots in a huge variety of colors! (Gastroenterologist Will Bulsiewicz, MD, previously told Well+Good that eating a wide variety of plants was the number one best thing you can do for your gut, which in turn affects your health as a whole.)

Kennedy also learned about how Traditional Chinese Medicine (TCM) is ingrained in many peoples daily lives in China. Similar to Ayurveda, TCM focuses on bringing balance to the body. One principle of TCM is qi, which is life energy that runs through the body. TCM doctors and healers often focus on ways to maintain qi through herbs, acupuncture, meditation, and movement. TCM is used prominently to prevent and treat disease and is a cornerstone of longevity in China.

Japan is home to one of the seven Blue ZonesOkinawabut Kennedy also spent time in Tokoyo and Kyoto meeting experts including Akitsugu Moriyama, the president of the Cancer Control Society of Japan; Mikako Harada, MD, an oncologist and expert in anti-inflammatory nutrition; and Takafumi Kawakami, a mindfulness expert and the deputy head priest of Shukoin Temple in Kyoto, Japan.

Kennedy says that the importance of mindfulness was a lesson he took home from Japan, something he saw through the elaborate matcha tea ceremonies that are held as well as in the types of exercises that are commonly practiced in the country. Japan is also a culture that really celebrates growing older as opposed to in the West where its something thats often viewed as a negative, he adds. (Just take Respect for the Aged Day, a national holiday in Japan where the elderly are given gifts from their local government and families gather together to honor their older loved ones.) Age-specific terminology is used to address older people. This complex of linguistic and social practices contributes to the acceptance and appreciation of old age, the paper reads. Feeling appreciated and valued can lead to feeling happy, which is directly linked to longevity.

While all the places Kennedy visited while filmingHealthy Long Life have their own unique ways of life, there are a few commonalities. Living a balanced life and finding ways to manage stress is key. So is eating lots of plants and flavorful herbs. Being connected to others is another way of living each culture valued. So maybe there isnt One Big Secret to living a healthy, long lifebut rather a few habits and traditions to cultivate daily.

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Experts Unpack Longevity Secrets From 5 Different Cultures Around the Globe - Well+Good

If you were to describe LeBron James to a person who had never seen a game of basketball before, or no awareness of the sport, I am not sure you would be able to do it. Where do you start?

Oh, here's a guy built like an upright cargo jet with the footspeed of a wide receiver, the grace and poise of a gymnast and the deftness of touch of a sculptor. He has the same calm intelligence as a chess grandmaster, or a Number 10.

He's also 36, in his 18th season and has only ever suffered one major injury - a groin issue in 2018/19 that kept him out for... 17 games. That's it. That's the longest amount of time he's ever missed.

Beyond that, he's been as ever-present in the NBA as the hoops and the hardwood, averaging roughly 27 points, 7 rebounds and 7 assists season in and season out. For some players, that stat line would represent the best night of their careers. For LeBron it's the minimum expectation, the same way you do not question whether the sun will rise in the morning. You know it will. You rely on it to.

It's something of a running joke now that he has not slowed down given, you know, the natural biological consequences of ageing and the fact James has played over 60,000 minutes of professional basketball, including playoffs.

To put that into perspective, you can combine the regular-season minutes of Lou Williams (34, 17th season) and J.J. Redick (36, 16th season), two other league stalwarts, and you would still have less than LeBron's regular-season total.

In fact, over the past three games LeBron has averaged 40 minutes and played four overtimes. The Lakers have won all three, including Wednesday night's 114-113 defeat of the Oklahoma City Thunder in which James hit the crucial three-pointer to send the game to an extra period, before then making a clutch steal on an inbounds play with four seconds remaining to secure the win.

Once again: this man is 36, in his 18th season, having played over 60,000 minutes in the NBA. There are paintings, fine wines, listed buildings and BitCoin traders envious of how LeBron James is ageing.

Yet, typically when we talk of an athlete's longevity, consistency and endurance, it usually comes at the cost of something else: the genuine ability to thrill. Take James Milner and Gareth Barry from the world of football for instance, two metronomes of the modern game but players who did not so much set the world alight as slowly and continuously drill right through to its core.

While they were undoubtedly exciting, dynamic and fearless in their youth, their permanence is what came to define them. The same for the likes of Tim Duncan, Jason Kidd, Ray Allen, Paul Pierce and Andre Iguodala in basketball. These are players we probably remember not for doing absurd things well into their 30s, but simply for still being there. Over time that tends to take on a remarkable quality in and of itself.

In our mind's eye we picture them as the grizzled veterans they became rather than the baby-faced destroyers of worlds they all once were during their ascendency.

LeBron James is different in many ways, but most startling is not that he can still do the things he has always done, from bulldozing straight through opponents to the rim or leaping out of the building to swat a shot into the rafters.

Most startling of all is that - somehow - he is still finding ways of improving on something already pretty close to basketball perfection.

This is probably the right moment to mention that LeBron is now one of the best snipers in the league, canning 39 per cent of his seven attempted threes per game. Those are almost Klay Thompson-level numbers. As per StatMuse, he is also averaging more points, rebounds, minutes, less turnovers and better field-goal, three-point and free-throw percentages than last season.

At what point do you give up waiting for the slump to come and just accept that this is it now, for eternity? That in a billion years when the Earth's surface heats, the oceans evaporate and all other life ceases to exist, only then will LeBron stop scoring 27 points a night, threading eye of needle passes and orchestrating another odd-parts and loose ends championship contender.

Tom Brady, understandably, has been the major talking point in the sporting world this week after winning his seventh Super Bowl at the age of 43. The most tiresome debate imaginable has once again reared its ugly head as the clickbait sites ask once and for all, until next month, who is the GOAT of the GOATs, the champion of champions. That misses the point of sport entirely. Brady's feats are staggering precisely because you cannot feasibly compare them to anything else that has happened before, in any sport, or even in any other aspect of life.

The same goes for LeBron. His career exists as a refutation of accepted truths. Of what the human body can do and what it can't. How long it can go on for. To contextualise him is impossible. You might wonder what the point is. Precisely that.

This is just another article, on another day, the morning after the night before when LeBron James put up 25 points, 6 rebounds and 7 assists and won a game of basketball. Again.

Originally posted here:
LeBron James' longevity and consistency will define him in the end as Los Angeles Lakers push for another title - Sky Sports

The first thing I decided to make was an antioxidant-rich beverage filled with cranberries, red currants, cherries, raspberries, lemon, and honey. I mixed those ingredients in the food processor, then added the concoction to hot water. Not only is the drink delicious, but it's also a simple way to increase your intake of immune-supporting vitamin C.

For the first few days, I didn't have much of an appetite (though I did retain my sense of taste and smell), so I opted for nutrient-rich and soothing drinks instead of solid food.

Along with the berry beverage, I also drank hot ginger tea with lemon, turmeric, and honey.Turmeric and ginger are high in anti-inflammatory properties, while hot water with honey also has a range of soothing health benefits.

For protein and gut support, I drank bone brothand when my appetite allowed for it, I'd use the broth as a base for vegetable soup containing blended leeks, broccoli, onions, herbs, and spices.

After the first three days, I continued drinking tea and incorporating berries and other antioxidant-rich foods into my diet. I also started transitioning back to my traditional everyday diet of nutrient-dense meals, with protein like chicken and fish.

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I'm A Longevity RD & Here's How I Took Care Of Myself When I Had COVID-19 - mindbodygreen.com

Those albums helped lay the foundation for Cordaes own art and their influence on his musical DNA is all too apparent across the 15 tracks of his lauded debut. Released in summer 2019 via Atlantic, The Lost Boy resonated with a bevy of fans because of its contemporary approach to hip-hops classic elements. And while the project impresses with slick punch lines and heavy soul samples, its the storytelling that brings you back time and again. Much like his predecessors, Cordae showed a penchant for connecting with his audience by addressing his own demons and making them feel universal.

On Family Matters Cordaes vocals are buoyed by an uplifting bassline while he bares all, sharing the stories of family members grappling with domestic violence and substance abuse. On Thousand Words, the 23-year-old emcee frames our generations over-reliance on social media and the warped perception of reality that can result. The transparency that anchors his songwriting isnt employed without intention. Thousand Words, along with others on the album, he explains, were written from a real place. Fans can connect to it and it can help them, you get what I'm saying? It can inspire them to let them know, it's okay to not come from the best neighborhood. It's okay not to grow up having everything. It's okay to have family issues, that's normal.

His comment points to what really sets Cordae apart from his contemporaries -- an unflinching appreciation for the weight his pen holds if used for something greater. Its that awareness that placed 18-year-old Cordae at the center of a 2016 Black Lives Matter protest in Washington, D.C. In the video recently posted to his Instagram account, Cordae freestyles over a megaphone, his words moving the crowd of hundreds with a spirited plea, Please expose the truth to the world on a global view.

To this day, Cordae doesnt necessarily consider himself an activist. Instead, he clarifies, Im just always going to do what I feel is right and speak on what I believe in strongly. As such, it was no surprise to see Cordae last summer at peaceful demonstrations protesting the killings of George Floyd and Breonna Taylor, not because it was a shot at an Instagrammable moment, but simply, because it felt like its where he should be. It's not even a black or white thing, it's just right and wrong. He pauses for a moment before questioning, How can you not see what's going on in the world to Black people all around? I empathize with that.

Last August, Cordae channeled that empathy into a politically-charged feature on Stevie Wonders triumphant protest record, Cant Put It In the Hands of Fate, rapping: Mass confusion, people in power commit collusion/indoctrinated students, Im the leader of the movement/takes lifetimes, trying to duck the school-to-prison pipeline/disenfranchised, its amazing Im in my right mind.

Cordae might be unsure to what degree his next album will touch on social justice or 2020s bleak realities but he knows one thing for certain -- the quarantine-induced self-reflection hes engaged in will be a creative north star. Musics global shutdown offered Cordae the time to read, write and reflect in a way he hasnt been able to back to back years on the road. Hes not the same artist or person that he was when he released his debut and he wants his sophomore release to reflect that growth. It's a completely separate idea than The Lost Boy. It's not going to be a Lost Boy Two.

More:
With a Pair of Grammy Nominations in His Rearview, Cordaes Focus is Longevity - Billboard

News

Elizabeth Francis recently celebrated her 111th birthday.

(KTRK via CNN)

HOUSTON (KTRK) -- It's no longer unusual to know or hear about someone who's at least 100 years old these days. In fact, there were more than 90,000 people in the U.S. who were over 100 years old in 2020, according to the Census Bureau.

But a Houston woman has gone 11 years past the century mark.

Elizabeth Francis is now an incredible 111 years old. When asked her secret to longevity,she said: "The Lord just blessed me ... I say, 'Thank you Lord' when I wake up in the morning, and I thank Him when I go to bed."

ABC13 was there last year whenFrancis turned 110. She even had Mayor Sylvester Turner asa special guest at her party.

Francis was born in Louisiana in 1909. The Houstonian celebrated her 111th birthday on Saturday.

Francis gets proclamations from the city and state every year she reaches another milestone. As for what she eats to stay healthy, her response is: "Everything."

"No, I'm not on a diet," she said. "I just eat what I feel like eating, what I know I like."

Francis lives with her daughter, who is 92 years old. Her granddaughter, Ethel Harrison, keeps a watchful eye on both of them. Harrison said people don't believe her when she tells people her grandmother's age.

Harrison has her own theory about why her family members live so long. Francis's oldest sister lived to be 106, and her baby sister lived until she was 95.

"I think for them, it was the food that they ate," Harrison says. "They cooked everything, and it was fresh. My grandmother had a garden."

But there's a surprising twist to this story. Francis is not only one of the oldest people in Texas, she also worked at Channel 13 in the 1970s. She recently reconnected with old friend ABC13 anchor emeritus Dave Ward via Facetime to catch up on some memories.

Ward recalls when Francis ran the coffee shop, and remembered her for always closing on time.

When a former mayor wanted to order after close, Ward said, "One of the managers walked down to the coffee shop and said, 'The mayor would like a hamburger.' Miss Elizabeth said 'The grill is closed, the mayor don't need no hamburger.'"

Francis said, "I say what I want when I want."

Her life continues to be full these days thanks to her place of worship, Good Hope Missionary Baptist Church, and her family.

In addition to her daughter, she also has three grandchildren, four great-grandkids, and two great-great-grandsons.

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Link:
111-year-old Houston woman shares secrets to longevity - - KTEN