StemCell Therapy

When it comes to ensuring that the body stays healthy, the liver is definitely at the forefront. Often referred to as the bodys personal detoxing system, the liver helps to keep your body healthy and clean by removing toxins from the body. If thats not enough, this vital organ is also responsible for destroying old blood cells, ensuring that nutrients are more easily absorbed, storing minerals, iron, and vitamin A, as well as producing essential proteins and cholesterol and produce bile to break down and digest fats. That said, its no wonder that people are concerned with maintaining the health of the liver, and as such if theres one trend that will never die, its a liver detox.

Before we get into the effectiveness of a liver detox, its best to first discuss what would bring someone to it. As mentioned, the liver is the bodys personal detox system, and if its compromised, then youre definitely going to feel the effects. That said, below are signs that your liver may need a little help;

Now while the average person may associate poor liver function with excessive alcohol consumption which is fair there are other facts that can compromise your bodys liver function. These include;

A liver detox, or cleanse, often takes the shape of fasting on cayenne-infused lemon water for a week, in hopes of cleaning your liver and even losing weight. Now, while this health fad is often featured on every health website known to men, there are a few concerns when it comes to liver detoxes and cleanses.

For one, these cleanses can be dangerous as they often encourage people to go on diets and fasts that may deprive them of essential nutrients, leading to deficiencies and malnutrition. Whats more, there have yet to be any scientific studies that support the benefits of liver detoxes. Whats more, the products that claim to help to detox the liver are not regulated. Essentially, there is a low chance of an unhealthy liver getting better because of a liver cleanse.

Liver detox may not necessarily be the best way to protect liver health. However, there are other ways that can help to protect it particularly through dietary measures. That said, below is a list of liver-friendly foods that you can add to your diet, boosting your bodys personal detoxing system.

Rich in antioxidants, green tea can do wonders for your health, and that includes your liver as well.

For instance, a Japanese study published in the British Medical Journal found a strong association between drinking 510 cups ofgreen teaper day and improved blood markers of liver health.

Additionally, separate research published in the International Journal of Molecular Medicine found that after drinking green tea for 12 weeks, patients with non-alcoholic fatty liver disease (NAFLD) noted an improvement in their liver enzyme levels. Researchers also noted that green tea may have helped to reduce oxidative stress and fat deposits in the liver.

Lastly, findings published in the Nutrition and Cancer journal revealed that drinking four or more cups a day of green tea can help to reduce your risk of developing liver cancer.

With that said, if youre looking to boost your liver health, its preferable to stick to buying green tea as opposed to green tea extracts. This is because some supplements have been found to damage the liver, as opposed to helping it.

A food group that consists of broccoli, cauliflower, brussels sprouts, and cabbage. These vegetables can help to boost liver health because they are rich in the compound glutathione.

While human studies are limited, animal studies have found that eating cruciferous vegetables may help the body remove toxins, and it may even slow down the progression of fatty liver disease in mice (1).

That said, a 2015 study published in the World Journal of Gastroenterology found that broccoli sprout extract helped to improve liver enzyme levels and decrease oxidative stress in men with fatty liver disease.

If youre looking for the ultimate snack food, then look no further than nuts. High in omega 3 fatty acids, as well as antioxidants and vitamin E, nuts are exactly what your health, and your liver, need.

For one, findings published in the World Journal of Gastroenterology found that, over a six-month period, 106 people with non-alcoholic fatty liver disease experienced improved levels of liver enzymes following their regular consumption of nuts.

Whats more, an observational study published in the Journal ofGastroenterologyandHepatology found a link between men who ate small amounts of nuts and seeds and an increased risk of developing NAFLD.

Olive oil is considered one of the best sources of healthy fat in the world, and this can help to benefit your liver.

Fat accumulation in the liver is one of the first signs of liver disease. That said, research published in the journal Diabetes Care found that consuming a teaspoon of olive oil a day helped not only improve liver enzymes, but also fat levels.

Berries, particularly the deep-hued ones like blueberries, blackberries, and raspberries, are rich in antioxidants known as polyphenols, and these plant compounds may help to protect the liver from damage.

According to an animal study published in the World Journal of Gastroenterology, the antioxidants commonly found in berries helped to slow down the development of scar tissue in the livers of rats.

Additionally, a test-tube study found in the Food Chemistry journal revealed that blueberry extract helped to inhibit the growth of human liver cancer cells.

Thats right. Believe it or not, your morning cup of coffee may be whats keeping your liver so healthy, as a result of its protective properties.

For instance, a study published in the Journal of Clinical Gastroenterologysuggested that coffee helps to reduce fat buildup in the liver. If thats not enough, the same study found that drinking coffee helps to lower the risk of permanent liver damage in people with chronic liver disease. Additionally, a separate study saw that drinking coffee can help reduce the risk of death in people with chronic liver disease (2).

As there are foods that can help to keep your liver healthy, there are also those that may affect its health. These include:

Your liver is a vital organ thats needed for various processes, in order to keep your body healthy. Now, while the efficiency of a traditional liver detox or cleanse is still up for debate, there are foods that can help protect its health.

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Liver Detox: 6 Foods To Boost and Cleanse Your Liver - Longevity LIVE

Your enjoyment of FIFA 20 depended on your patience, longevity with the series and whether or not you do anything with the game other than open Ultimate Team packs.

It was just another year for EA's footy machine, but it didn't roll past without serious flak on YouTube and social media from angry gamers who demanded to know why everything was so stale. Bugs and glitches were popping up all over the place too, and the whole project became 2019's latest reminder that annual franchises might not be worth the cash every time they're pumped out onto store shelves.

At this stage, a year off would be a blessing. That's not going to happen though, and it leads many to worry about what FIFA 21 will bring. This will be the dawn of yet another new era for EA's uncompromising juggernaut, and they're not the only ones vying to make it special. Those who venture beyond FIFA's limits know there's stiff competition for the football gaming crown.

Start chewing those fingernails, FIFA lovers, because there are loads of reasons to fret about what 21 will be like...

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FIFA 21: 10 Reasons To Be Worried - WhatCulture

NEW YORK, United States Nancy Pelosi has always worn Michael Kors. She told him his clothes make her feel strong, and God knows thats something she needs in Washington. Before his show on Wednesday, Kors was talking about how its more important than ever to take a stand for your principles. If youre going to do battle, youd better feel confident doing it, he said. Thats the simple truth. If youre tugging at your dress, and youre crippled in your shoes, and you cant handle your bag Kors proudly pointed out there wasnt a stiletto heel or a skintight dress in his new collection. And we dont have a bag in the show thats not hands-free. Instead, his woman was dressed for the "real" world. We need a chic security blanket, thats the reality.

His business turns 40 next year, and he claimed hes been thinking about clothing in terms of a security blanket more or less the whole time. Kors has always been ready with a raft of references for each new collection usually a Hollywood style icon but with this major anniversary approaching, hes begun to reference his own work.

There sure is enough of it. Two decades ago, Naomi Campbell modelled a cape in a Kors show, Tina Barney later photographed writer Joan Didion wearing it. We got a phone call saying Joan wanted to buy the cape and I couldnt breathe, the designer recalled. Her writing, her sense of stylishness always knocked me out. Give me Mailbu Joan Didion and Im there. Kors owns Barneys photo. I wake up to it every day. That cape is graphic, it stands the test of time, Kaia Gerber is wearing it in the show today, 21 years later.

Remember in Citizen Kane how the sled called Rosebud was a childhood memory representing all that was simple, good and true for the business titan Charles Foster Kane as he lay dying? Not wanting to sound morbid or anything, but I wondered if the cape might be Korss Rosebud, the thread that runs through his lifes work. Hes a mad movie buff, so the idea appealed to him. He certainly gave us a show that was the cinematic apotheosis of the cape, in every possible guise: Victorian detective, highwayman, Zorro, poncho, blanket. Coats and capes combined, collars flared into capelets.

The simple, good and true bit worked because what Kors was after was a sense of the cosiness and comfort of country dressing given a bit of spit and polish for city life. Now more than ever, the simple truth is that our customers dream of being able to unplug and get out of town, but thats not the way life works out.

So Kors sold the fantasy the joy of wide-open spaces as efficiently as hes always plugged his glamorous Hollywood-spiked re-visions of Americana. The escapism, the honesty of the West is one of the things you can be proud of as an American, no matter what. There was a pony print trench, and a full-on riding look in amidst all the caped cosiness.

Classics. Longevity. Kors has been brooding on them. Funny thing is, we now have a whole new generation of customers who never thought about fashion as investment, but the sustainability conversation has woken them up. They say, I dont have to buy a dress to wear twice to post on Instagram, I can actually buy something thats beautifully made and hang onto it. Intelligently, thats what Ive always thought but now were seeing a whole new generation approaching that idea for a different reason. Thats amazing.

But, honestly, is it so amazing, when youre presented with something as effortlessly, common-sensically glamorous as a slinky grey cashmere turtleneck elongated over a fishtail skirt pav-ed with subtly gleaming graphite sequins and anchored by lug-soled boots? At what stage in the devolution of humankind is that not going to look good?

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Michael Kors Broods on Longevity | Fashion Show Review, Ready-to-Wear Autumn 2020 | BoF - The Business of Fashion

Right now, Stanford University is addressing a pressing and fascinating question:

What happens to society when everyone starts living to 100? How will we stay physically fit, financially stable and mentally sharp, especially in that back half?

Exploring these questions is the goal of the Stanford Longevity Project. To answer them, theyve partnered with major brands like Wells Fargo, Instructure, and Principal to help research key elements like financial security, lifelong learning, and healthcare.

Despite Americas average life expectancy declining the past couple years due to more overdoses, suicides and alcohol-related illnesses, people are going to be able to live longer. Strong advancements have been made in cancer. This month, the U.S. saw its sharpest one year decline in cancer death rate. That will save millions of lives alone.

But this isnt just a health and wellness conversation. What this presents are multiple opportunities in multiple verticals for marketers.

One of the biggest trends at CES this month was a new generation of healthcare wearables. There were earbuds designed to detect blood pressure for those with hypertension, temporary tattoos that tell you when to get out of the sun, smart glasses that assist people with dyslexia and watches that detect sleep apnea. These technologies are all discreet, easy to use, and built in to everyday things we already use.

We are heading toward a near future in which every human body will have a functioning check engine light. You can imagine how much better healthcare will be when a sensor will tell you something needs attention, rather than panicked scrolling through WebMD.

We will have the ability to know when something is wrong and immediately trigger tests, medication and treatment. Imagine if that sensor, using the IoT, could immediately send and fill a prescription for you.

This is all coming down the pipeline, and its going to help us live longer. Its also going to change the way marketers do their jobs and open up countless new opportunities to reach new audiences.

Heres what some of those opportunities will look like.

Cincinnati has one of the best healthcare startup scenes in the country. Cincinnati Childrens Hospital is ranked #3 nationally. CincyTech has raised nearly a billion in healthcare follow-on investment over the past ten years.

The common thread these organizations share is they are tackling high-use issues in different ways. That includes everything from small, wearable, injectable devices (Enable Injections) that can be used for a multitude of conditions, to analyzing peoples sweat to ensure proper medication dosing (Eccrine Systems).

One of the most interesting might be Sense Diagnostics because their simple device addresses a huge need: stroke detection. Right now there isnt a good way to tell which kind of stroke (transient ischemic, ischemic, or hemorrhagic) someone is having in the field. An ambulance with this non-invasive device will be able to quickly diagnose which stroke is occuring, allowing them to begin the best possible treatment immediately.

As people begin living longer, well see that the traditional approach to education and work must change. A longer living workforce will be more likely to need to reskill for second and third careers.

Private equity firm Thoma Bravo is buying Instructure (makers of the popular Canvas Learning Management System) for $2 billion, precisely because of the projected growth and opportunity in education as people extend their careers.

Of course, four-year higher education will still exist. But new avenues and approaches to learning will emerge as supplemental or alternative ways of reskilling for jobs that will target people in their 60s, 70s, and 80s.

Curricula will obviously also have to adapt, becoming more flexible, personalized, and life-long. Being able to brush up every three months on relevant skills via a subscription model may be a better future model for education than entering a full-time program. Most of the marketing opportunities will be around aiding employers, because they have the budgets and the competition for retention.

Living longer changes a persons entire financial strategy.

Most standard retirement principles assume that retirement will last a maximum of 30 years. The commonly-used "4% rule" of retirement is an example of this. However, if you live to 100 or beyond, your retirement could last 35 years, 40 years, or longer, said Nathan Hamilton, director and industry analyst at The Ascent from The Motley Fool.

A deferred annuity could be worth a look. Essentially, you put some money into an annuity when you first retire (or earlier), but that won't start paying out until a certain agesay, 80 or 85. The idea is that even if your retirement nest egg is getting low as you get older, this move guarantees you a predictable income stream for life.

How we invest may also change as we look to create steady income streams that kick in throughout retirement rather than just upfront. This also may inevitably cause people to work later and longer especially as our workforce trends farther away from physical labor to more mental and creative labor.

The biggest takeaway here isnt that living longer will impact one thing. It will impact everything.

As humans, we need to think about that for ourselves and our future generations. And as marketers and entrepreneurs, we can start thinking about ways we can make that reality better, more productive, and more secure for people.

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Marketing To 100-Year-Olds: How Longevity Will Transform Finance, Healthcare And Education - Forbes

THE WOODLANDS, TX - Larry Deckerhoff, MIM, well-known adviser to companies and entrepreneurs in The Woodlands (Texas), announced the continuation of The Woodlands Lunch Forum with a luncheon event scheduled for Friday, 28 February 2020 at Amerigos Grille, 25250 Grogans Park Drive in The Woodlands. The Forum is scheduled to start at 11:30 AM and last one and a half hours. Mr. Deckerhoff indicated,

The theme of this Lunch Forum is Advanced Health for the New Millennium, Immunotherapy and Rejuvenation. Among our featured speakers will be Ralph Fucetola JD, President of The Woodlands own Institute for Health Research - http://www.InHeRe.org. He will be joined by two experts in rejuvenation and immunotherapies. The short presentations will leave plenty of time to connect and enjoy the extraordinary cuisine at Amerigos Grille.

The Institute, founded in 1998, focuses on leading-edge, natural and nutritional support for vigorous aging and powerful immunity. The Institute President will introduce advanced approaches to health and longevity through the featured speakers who are positioned to inform and enlighten, in cooperation with NutraSpace, Health Matching Accounts and Natural Solutions Foundation.

Interested participants are requested to RSVP to stephen.contreras1@hotmail.com the requested donation of $50.00 includes a three course gourmet lunch. Donations in excess of luncheon value are tax-deductible.

The President of the Institute concluded:

We look forward to a growing presence in The Woodlands community as our alliances with local and regional companies and researchers continue to mature. Our research interests include areas as diverse as longevity nutrition, immunotherapy and autism retrieval.

Speakers:

1. Ralph Fucetola JD President, the Institute for Health Research http://www.InHeRe.org2. Bill Hayes, NutraSpace http://www.NutraSpace.com3. Elliot Gorog, HMA - http://www.HealthMatchingAccounts.com

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The Woodlands Lunch Forum to Host Longevity and Health Event February 28th at Amerigo's Grille - Woodlands Online

TEMPLE, TX Baylor Scott and White doctors and researchers are teaming up with experts from across the state to improve the lives of heart failure patients.

Doctors explained to 25 News, those diagnosed with heart failure often have additional ailments, like arthritis, which often impede with the patients ability to exercise; and without exercise heart failure patients conditions often worsen.

Researchers at Baylor Scott and White are efforting a new study, conducting trails on alternative exercise regimens for their patients, by using aquatic therapy.

"The hypothesis is that compared to land based exercise they are going to have actually more mobility both before and after exercise and improve cardiac function" explained Catherine McNeal, M.D PHD Medical Director of Cardiac Rehabilitation at Baylor Scott and White.

McNeal's cohort, Albert Hicks, M.D MPH Medical Director of Heart Failure and Transplant, Baylor Scott and White, further explaining "we know that from many trails including our H.F. Action trail that heart failure patients who do cardiac rehab actually have increased survival...in the pool they have an opportunity to really not only get their heart rate up but also to do an activity that is something that they can do for the majority of the rest of their life."

The Baylor Scott and White team is collaborating with experts in aquatics at University of Texas and bio-engineers at Texas A&M University in their research.

Funded internally by the Baylor Cardiovascular Research Center, the teams efforts have all pointed towards positive results.

Awarded a small grant from the National Institutes of Health (NIH) the team looks forward to their findings and potentially positively impacting the lives of heart patients nationally.

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Local News Doctors in Temple experimenting with aquatic therapy to improve longevity of heart patients Erin - KXXV News Channel 25

Anopheles arabiensis is an opportunistic malaria vector that rests and feeds outdoors, circumventing current vector control methods. Furthermore, this vector will readily feed on animal as well as human hosts. Targeting the vector, while feeding on animals, can provide an additional intervention for the current vector control activities. Agricultural animals are regularly vaccinated with recombinant proteins for the control of multiple endo- and ecto-parasitic infestations. The use of a Subolesin-vaccine showed a mark reduction in tick reproductive fitness. The orthologous gene of Subolesin, called Akirin in insects, might provide a valuable species-specific intervention against outdoor biting An. arabiensis. However, the biological function of this nuclear protein has not yet been investigated in this mosquito. The effects on An. arabiensis lifetable parameters were evaluated after Akirin was knocked down using commercial small-interfering RNA (siRNA) and in vitro transcribed double-stranded RNA (dsRNA). The siRNA mediated interference of Akirin significantly reduced fecundity by 17%, fertility by 23% and longevity by 32% when compared to the controls in the female mosquitoes tested. Similarly, dsRNA treatment had a 25% decrease in fecundity, 29% decrease in fertility, and 48% decrease in longevity, when compared to the control treatments. Mosquitoes treated with Akirin dsRNA had a mean survival time of 15-days post-inoculation, which would impact on their ability to transmit malaria parasites. These results strongly suggest that Akirin has a pleiotropic function in An. arabiensis longevity and reproductive fitness.

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Characterising the effect of Akirin knockdown on Anopheles arabiensis (Diptera: Culicidae) reproduction and survival, using RNA-mediated interference....

KEY POINTS

Lifestyle is among the determinants of how long you may live. For those who regularly go on excessive alcohol drinking, consuming diets full of trans fats, and observe many other unhealthy practices, may not expect to live long.

Scientists and health experts have found long ago that to have a healthier and longer life, you should exercise regularly and consume a healthy and balanced diet. You should also limit your alcohol intake and quit smoking.

It is not at all surprising that observing a healthy diet can help a lot in improving longevity. With thousands of information as to what can be the best diet, however, you can easily get confused as to which one to follow.

Fortunately, recent research has shed light on what could possibly be the best diet that can help improve longevity and at the same time, help prevent cancer. live healthy life vegan diet increase longevity Photo: Rita E - Pixabay

Vegans May Have an Edge

Findings of a new study that were published in The Journal of Nutrition concluded that the secret to a long life might lie in veganism. Leading scientists and health experts agree, saying that a vegan diet helps in warding off a lot of diseases, including cancer.

Researchers revealed that based on the findings of their recently concluded study, the bodies of vegans contain the most antioxidants. According to health experts, this is primarily due to the high intake of vegetables and fruits.

It was also found out that those who follow a vegan diet have considerably lower death rates compared to meat-consumers. This new study reinforces findings of past researches that found a vegetarian diet, which consists mostly of nuts, wholegrain, legumes, fruits, and vegetables, lowers the risk of developing major ailments. It also helps you live longer.

The Vegan Research

Researchers from Loma Linda University have proven that men who follow vegan diets live an average of ten years longer compared to non-vegetarian men. Women following vegan diets, on the other hand, can add six more years of a healthy life, helping them reach an average age of 85 years.

Loma Linda University researchers also comprised the same research team that came up with the groundbreaking Adventist Health Study-1, a study that examines nutrition and life expectancy.This study was regarded as a benchmark in the nutrition world because of its comprehensiveness in terms of the number of participants and the length of time conducted.

Loma Linda researchers, for fourteen long years, tracked the diets, lifestyle, and ailments among 34,000 volunteers who do not drink or smoke. They found several habits that could add years to your life.

For one, the volunteers were consuming plant-based foods and were also consuming a handful of nuts regularly. They are also physically active and maintain a healthy weight. According to the researchers, these lifestyle habits could give you an extra two to three years of a fruitful life.

Read more from the original source:
Protect Yourself Against Cancer And Increase Life Expectancy By Eating The Best Diet - International Business Times

To some longevity acolytes, stem cells promise the secret to eternal youth. For a hefty fee, you can pay a startup to extract your own stem cells and cryogenically freeze them, in the hope that they can one day be used in a treatment to help extend your life.

Other firms let you bank stem cells from your babys umbilical cord and placenta after childbirth, if youre convinced the high cost represents an insurance policy against future illness. Or you can follow the example of Sandra Bullock and Cate Blanchett and opt for an anti-ageing cream made with stem cells derived from the severed foreskins of newborn babies in South Korea.

Stem cells are the parent cells which give rise to other cells in our bodies. Since scientists first isolated human embryonic stem cells in a lab and grew them over 20 years ago, they have been mooted as a source of great hope for regenerative medical treatments, including for age-related degenerative conditions such as Parkinsons, Alzheimers, heart disease and stroke.

But apart from a few small-scale examples, the only stem cell-based medical treatment practised in clinics uses haematopoietic stem cells found in the blood and bone marrow which only produce blood cells for transplants in blood cancer patients. These cells are taken from a patients sibling or an unrelated donor, before being infused into a patients blood, or theyre taken from a patients own blood before being reinfused. The procedure has been used to treat blood malignancies for almost half a century, and recently multiple sclerosis too. So how likely is it that the predictions about stem cells' longevity-enhancing powers will become a reality?

In September 2019, Google banned ads for unproven or experimental medical techniques such as most stem cell therapy, citing a rise in bad actors attempting to take advantage of individuals by offering untested, deceptive treatments [that can often] lead to dangerous health outcomes. The decision was welcomed by the International Society for Stem Cell Research, which emphasised that most stem cell interventions remain experimental. Selling treatments before well-regulated clinical trials have been done, the body said, [threatens public] confidence in biomedical research and undermines the development of legitimate new therapies.

Its easy to see how less scrupulous companies can exploit the allure of stem cells, which seem to occupy a place in our collective consciousness as a kind of magical elixir. High hopes for stem cell-based therapies have grown since 2006, when the Japanese biologist Shinya Yamanaka created a new technology to reprogram adult cells, such as skin cells, into a similar state to embryonic stem cells, which are pluripotent, meaning they can develop into any tissue in the body. The Nobel prize-winning breakthrough was hailed as a major step in the study of stem cells without the need for controversial embryo research, and towards the use of these human induced pluripotent stem cells to regenerate damaged or diseased organs or effectively grow new spare parts which could treat the life-limiting and life-shortening illnesses associated with ageing.

Gerontologist Aubrey de Grey, whose Strategies for Engineered Negligible Senescence (SENS) research foundation aims to eliminate ageing-related diseases, thinks the chances well soon have stem cell based therapies are high. For anything that's in clinical trials, you're talking about maybe five years before it's available to the general public, he says, citing stem cell treatments for Parkinsons disease, currently being tested in phase two clinical trials, as one of the developments he thinks is likely to come soonest.

However, given that these trials involve a relatively small number of participants and most clinical trials ultimately fail, his predictions might be overly optimistic. Often described as a maverick, De Grey believes that humans can live forever and there is a 50 per cent chance medical advances of which stem cell therapies will play an important part will make this a reality within the next 17 years. Though living forever, he says, is not the ultimate goal but a rather large side effect of medicine which will successfully prevent or repair the damage that comes with ageing.

For New Jersey-based Robert Hariri, who co-founded Human Longevity Inc, which set its sights more modestly on making 100 the new 60, stem cells derived from placentas present especially exciting opportunities. A biomedical scientist, surgeon and entrepreneur, Hariri says his current venture Celularity which is focused on engineering placental cells, including stem cells, to create drugs for cancer and other conditions is not as concerned about the actual age number, but about preserving human performance as we age and treating the degenerative diseases that rob us of our quality of life.

Many of those working in the field, however, remain cautious in their optimism. Researchers have highlighted the potential risks of giving pluripotent cells to patients, whether they are induced or embryonic, as these cells can develop cancer-causing mutations as they grow.

Davide Danovi, a scientist at Kings College Londons Centre for Stem Cells & Regenerative Medicine, says the path to stem cell-based therapy is very long and full of hurdles. The supply chain involves challenges, he says. On the one hand, allogeneic treatments those with stem cells derived from one individual and expanded into big batches to create cells to treat many individuals have the advantage of being similar to the traditional pharmaceutical business models. The product is clear, its something that comes in a vial and can be scaled up and mass produced, Danovi says. But this treatment can present a greater risk of rejection from the patient, as opposed to the more bespoke autologous option which is more expensive and time-consuming as it involves extracting a patients own stem cells before reprogramming them.

Danovi is most excited by the potential of stem cells to treat age-related macular degeneration. In 2017 Japanese scientist Masayo Takahash led a team that administered transplants of artificially grown retinal cells created from induced pluripotent stem cells taken from donors to five patients with the eye condition, which can cause blindness, and theyre reported to be doing well. The eye, he says seems to be a place where immunity plays less of a role relative to other issues, so you can host cells which come from another individual with fewer problems [of rejection]. But, with other organs such as the liver, he says there are major conceptual problems with creating enough tissue. Its like the clean meat burger - you're talking about a production that is, in many cases, not easy to reach with the current technology.

Hariri believes placentas will solve some of the production challenges crucially, theyre an abundant commodity, with the vast majority thrown out after childbirth. His interest was sparked 20 years ago when his oldest daughter was in the womb: When I saw her first ultrasound in the first trimester, the placenta had already developed into a relatively sizable organ, even though she was just a peanut-sized embryo. Id been taught that the placenta was nothing more than an interface, but [if that was the case], you would expect that it would grow at the same rate as the embryo. His curiosity piqued, he began to see the placenta not as an interface but as a biological factory, where stem cells could be expanded and differentiated to participate in the development of that foetus. That intrigued me and I started to collect placentas and just, you know, basically disassemble them.

Placentas have numerous benefits, he says they dont carry the same ethical controversy as embryonic stem cells, for one thing. Scientists working on embryonic stem cells have to destroy an early embryo, and that option yields them a dozen cells, which have to be culture-expanded in the laboratory into billions of cells. In contrast, the placenta houses, billions and hundreds of billions of cells, which can be expanded as well, but you're starting out with a dramatically larger starting material.

Increasingly, scientists in the anti-ageing sphere are focusing on an approach that seems like the opposite of planting fresh stem cells into our bodies. Experts such as Ilaria Bellantuono at Sheffield Universitys Healthy Lifespan Institute are working towards creating senolytics medication that could kill off our senescent cells, the zombie cells that accumulate in tissues as we age and cause chronic inflammation. I think stem cells are very good for specific disease, where the environment is still young, Bellantuono says, but the data in animal models tells us that senolytics are actually able to delay the onset and reduce the severity of multiple diseases at the same time for example, there is evidence for osteoarthritis, osteoporosis, cardiovascular disease, Alzheimer's, Parkinson's, and diabetes. She explains that while human trials are still in their early stages, senolytics are likely to be more cost-effective than stem cell therapy and the status quo of older patients taking multiple pills for multiple diseases, which can interact with each other. Besides, she adds, they may actually work in tandem with stem-cell based therapies in the future, with senolytics creating a more hospitable environment in tissues to allow stem cells to do their work.

And as for the so-called penis facial? Its far from the only ultra-expensive stem cell skincare making bold anti-ageing claims but youre probably better off saving your money, as you are with the experimental medical treatments on offer. Stem cells are definitely exciting but theyre not the key to eternal youth. At least, not yet.

Robert Harari will be one of the speakers at WIRED Health in London on March 25, 2020. For more details, and to book your ticket, click here

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Are stem cells really the key to making humans live longer? - Wired.co.uk

Global Longevity and Anti-senescence Therapy Market 2020: Research Methodology

The global Longevity and Anti-senescence Therapy Market is expected to grow at a significant pace, reports Acquire Market Research. Its latest research report, titled [Global Longevity and Anti-senescence Therapy Market Report, History and Forecast 2020-2026, Breakdown Data by Manufacturers, Key Regions, Types and Application], offers a unique point of view about the global market. Analysts believe that changing consumption patterns are expected to have a great influence on the overall market. For a brief overview of the global Longevity and Anti-senescence Therapy market, the research report provides an executive summary. It explains the various factors that form an important element of the market. It includes the definition and the scope of the market with a detailed explanation of the market drivers, opportunities, restraints, and threats.

Global Longevity and Anti-senescence Therapy Market: Segmentation

The chapters of segmentation allow the readers to understand the aspects of the market such as its products, available technologies, and applications of the same. These chapters are written in a manner to describe their development over the years and the course they are likely to take in the coming years. The research report also provides insightful information about the emerging trends that are likely to define the progress of these segments in the coming years.

Download Sample PDF of Longevity and Anti-senescence Therapy Market Report @https://www.acquiremarketresearch.com/sample-request/306097/

Top Key players Mentioned in the Global Longevity and Anti-senescence Therapy Market Research Report: CohBar, TA Sciences, Unity Biotechnology, AgeX TherapeuticsInc, PowerVision Inc.

Types covered in the Longevity and Anti-senescence Therapy industry are Hemolytic Drug Therapy, Gene Therapy, ImmunOther.

Applications covered in the report are Hospital, Medical Service Institution, Drug and Device Sales.

Global Longevity and Anti-senescence Therapy Market: Regional Segmentation

For a deeper understanding, the research report includes geographical segmentation of the global Longevity and Anti-senescence Therapy market. It provides an evaluation of the volatility of the political scenarios and amends likely to be made to the regulatory structures. This assessment gives an accurate analysis of the regional-wise growth of the global Longevity and Anti-senescence Therapy market.

The Middle East and Africa (GCC Countries and Egypt)North America (the United States, Mexico, and Canada)South America (Brazil etc.)Europe (Turkey, Germany, Russia UK, Italy, France, etc.)Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)

Global Longevity and Anti-senescence Therapy Market: Research Methodology

The research methodologies used by the analysts play an integral role in the way the publication has been collated. Analysts have used primary and secondary research methodologies to create a comprehensive analysis. For an accurate and precise analysis of the global Longevity and Anti-senescence Therapy market, analysts have bottom-up and top-down approaches.

Global Longevity and Anti-senescence Therapy Market: Competitive Rivalry

The research report includes an analysis of the competitive landscape present in the global Longevity and Anti-senescence Therapy market. It includes an assessment of the existing and upcoming trends that players can invest in. Furthermore, it also includes an evaluation of the financial outlooks of the players and explains the nature of the competition.

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Strategic Points Covered in TOC:

Chapter 1: Introduction, market driving force product scope, market risk, market overview, and market opportunities of the global Longevity and Anti-senescence Therapy marketChapter 2: Evaluating the leading manufacturers of the global Longevity and Anti-senescence Therapy market which consists of its revenue, sales, and price of the productsChapter 3: Displaying the competitive nature among key manufacturers, with market share, revenue, and salesChapter 4: Presenting global Longevity and Anti-senescence Therapy market by regions, market share and with revenue and sales for the projected periodChapter 5, 6, 7, 8 and 9: To evaluate the market by segments, by countries and by manufacturers with revenue share and sales by key countries in these various regions

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Customization Available

With the given market data, Researchers offer customizations according to the companys specific needs. The following customization options are available for the report:

Regional and country-level analysis of the Longevity and Anti-senescence Therapy market, by end-use.

Detailed analysis and profiles of additional market players.

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Acquire Market Research is a market research-based company empowering companies with data-driven insights. We provide Market Research Reports with accurate and well-informed data, Real-Time with Real Application. A good research methodology proves to be powerful and simplified information that applied right from day-to-day lives to complex decisions helps us navigate through with vision, purpose and well-armed strategies. At Acquire Market Research, we constantly strive for innovation in the techniques and the quality of analysis that goes into our reports.

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Longevity and Anti-senescence Therapy Market 2020 Specification, Growth Drivers, Industry Analysis Forecast 2026: CohBar, TA Sciences, Unity...

The Durst Organization and The Port Authority of New York and New Jersey announced a half dozen new leases at One World Trade Center.

DADA Holdings LLC has signed a five-year lease for 4,786 s/f on the 71st floor; Princeton Longevity Center signed a 10-year lease for 11,075 s/f on the 71st floor. This will be both DADA and Princeton Longevitys first offices in New York City.

Ichnos Science Inc., moving its offices to New York City from Paramus, New Jersey, signed a seven-year and five-month lease for 10,847 s/f on the 76th floor.

Pison Stream Solutions signed a three-year lease for 10,804 s/f on the 49th floor of OWTC, making the building their global headquarters.

Also signed were two expansion deals. Symphony Communications Services has signed a one-year lease for 3,510 s/f on the 45th floor, bringing their total square footage on the floor to 12,100 s/f.

Additionally, Augustus Intelligence signed a five-year lease for 6,475 s/f on the 77th floor of OWTC, doubling their footprint with a move from the 45th floor.

We are extremely pleased with the leasing activity at One World Trade Center, said Jonathan (Jody) Durst, President of The Durst Organization.

We are beginning the year by welcoming our newest tenants DADA Holdings, Ichnos, Princeton Longevity and Pison and celebrating the success of Symphony and Augustus with their office expansions at One WTC.

Princeton Longevity Center was represented by Steven Rotter, Blake Goodman and Justin Haber of JLL.

Ichnos Sciences was represented by Cushman & Wakefields Drew Braver and Mark Zaziski.

Michael Thomas and Aidan Campbell of Colliers represented Pison. Symphony Communications Services was represented by Christopher Foerch of Savills.

And Augustus was represented by Carol Engel of CS Engel and Associates. The landlord was represented by Senior Managing Director Eric Engelhardt and Managing Director Karen Kuznick of The Durst Organization and the Newmark Knight Frank team of David Falk, Jason Greenstein, Peter Shimkin, Hal Stein and Travis Wilson.

Augustus Intelligence builds artificial intelligence products and secure infrastructure services to help enterprise clients reinvent themselves.

Pison Stream Solutions is a global leader in the research and development of chemical coatings platforms for niche markets. They implement their systems across defense, aerospace, automotive, antimicrobial, renewable energy applications, and additive platforms.

Princeton Longevity Center is a next-generation medical facility combining the most advanced technology with an integrated and individually tailored Preventive Medicine program.

A fully integrated, global biotechnology company with the spirit of a start-up, Ichnos Sciences is shifting the way the world thinks about innovation in medicine through its research and development of transformative, disease-centric treatments in oncology, autoimmune disease and pain.

The company, with headquarters in Paramus, N.J., is rapidly advancing a clinical-stage pipeline of novel, first-in-class candidates designed to address complex diseases and treat patients holistically.

With a patented BEAT technology platform along with pioneering teams in Switzerland and India, Ichnos Sciences has a mission to provide breakthrough, curative therapies that will hopefully extend and improve lives, writing a new chapter in healthcare.

Symphony offers a secure team collaboration platform that transforms the way users communicate effectively and securely with a single workflow application.

Symphony was founded in October 2014 and is headquartered in Palo Alto, CA, with offices in Hong Kong, London, New York, Paris, Singapore, Sophia-Antipolis, Stockholm and Tokyo.

One World Trade Center is the tallest building in the Western Hemisphere and home to the largest community of media and tech innovators.

The 3.1 million-square-foot LEED Gold Certified skyscraper features premier office space and some of the most spectacular views in the world.

On the 64th floor, One World Commons offers 25,000 s/f of tenant amenities including a world-class business and social hub fostering workplace creativity, collaboration, and community.

Built by The Port Authority of New York and New Jersey and The Durst Organization in a unique public-private partnership, The Durst Organization is responsible for marketing, leasing, and managing the property.

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Durst Organization sees flurry of new business at 1 WTC - Real Estate Weekly

TOKYO A Japanese man with a sweet tooth who believes in smiles has become the worlds oldest male at 112 years and 344 days old, according to Guinness World Records.

Chitetsu Watanabe, who was born in Niigata in northern Japan in 1907, received a certificate for his accomplishment on Wednesday at a nursing home in the city.

The previous record holder, Masazo Nonaka, another Japanese, died last month. The oldest living person is also Japanese, Kane Tanaka, a 117-year-old woman.

Until about a decade ago, Watanabe used to do bonsai, the Japanese traditional art of raising small sculpted trees, and had his work exhibited.

These days, he loves desserts such as custards and cream puffs, Guinness said.

Watanabe graduated from agricultural school and then moved to Taiwan to work at Dai-Nippon Meiji Sugar on sugar cane plantation contracts.

He lived in Taiwan for 18 years. He married Mitsue and they had five children, Guinness said in a statement.

After the end of World War II, Watanabe returned to Niigata and worked for the prefectural government until retirement. He also grew fruit and vegetables on the family farm.

Asked about the secret to longevity, Watanabe has this advice: Dont get angry and keep smiling.

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Worlds oldest man, 112, shares the secret to longevity - Tampa Bay Times

I want to start by congratulating Damian [Green] and the whole APPG on the brilliant work youve done to get this issue onto the agenda.

Today is a day for detailed discussion about the proposals in your new Strategy.

But before we get to the policy I want to say a few words about the (small-p) politics.

Among policymakers especially in government our ageing society has traditionally been framed as a problem, a liability.

A source of pressure on public services. An unwelcome modern trend, like cybercrime or falling bee numbers.

But this is looking at things through the wrong end of the telescope.

Because of course its great news were all living longer.

And language matters. The words we use colour perception.

So lets hear less about our ageing society, and more about healthy longevity.

Less about the burden and the pressure and more about the reward of getting this right.

Because our final years should be an act of enjoyment. Not a task of endurance.

That positive framing is important because too often as a society we sweep these issues under the carpet.

We dont like to think about getting older. We dont like to think about our bodies failing. So we dont give healthy ageing the attention it deserves.

Which brings me to the policy question.

For most of the 70 years the NHS has been in existence weve focused on life span.

This has seen extraordinary successes.

Mass-vaccination. The collapse in the adult smoking rate from 45% in the 1970s to 14% today.

But as the NHS enters its eighth decade, it needs to focus more on health span: the number of years a person can expect to live healthily and independently.

In our manifesto we committed to an extra 5 healthy years by 2035. This is the primary long-term clinical goal weve set the NHS.

Both parts are important: extra years and healthy years. Adding years to life, and life to years.

The next question is how do we get there?

Today I want to touch on 3 things.

The first is place and its relationship to people.

Because however you choose to measure the evidence is clear: your chance of a healthy old age is closely tied to where you live.

A man born in Blackpool can expect only 53 years of healthy life, while a man born in Buckingham gets 68.

Thats wrong.

Tackling this postcode inequality matters to this government. Its what we mean when we talk about levelling up.

The underlying factors are a complex interaction between demography and economy.

But because healthcare inequalities are geographically concentrated, it means we can take a targeted approach.

This starts with improving access to healthcare.

50 million more GP appointments. 50,000 more nurses. 40 new hospitals. Its what those flagship commitments are all about.

And we can boost access even further: by using more of our brilliant community pharmacists as a first port of call for people seeking primary care, by using technology to reduce the burden on clinicians, by having everyone in every part of the NHS operating right at the top of their licence.

But having the right NHS services is just one part of building healthier places.

Its about warm, properly insulated homes, low-crime neighbourhoods, and action on the environment like our cross-government work on air quality.

Its the kind of urban design that supports healthy living, more opportunities for walking and cycling bearing down on the 40% of car journeys that are less than 2 miles.

This is something that the Prime Minister is strongly personally committed to, and our announcement yesterday of 250 miles of new cycling routes is another milestone on that journey.

One of the biggest health impacts a place can have is whether it supports good local jobs.

By good jobs I mean jobs that are purposeful and rewarding, not just well paid. Where employers invest in things like mental health or muscular-skeletal support as part and parcel of being a good employer.

And this absolutely includes jobs in the NHS.

As one of the countrys biggest employers, the NHS can have an outsized impact on the opportunities available to local communities.

For example, Im proud of the work were doing with the Princes Trust to get 10,000 school leavers job-ready for roles in the NHS and social care.

The second part of this agenda and closely linked to place is a recognition that healthy longevity is not just the NHS.

Only around a quarter of what leads to longer, healthier lives is the result of what goes on in hospitals.

The rest is down to genetics, the environment, and the lifestyle choices we make.

Yes, we can and we should use the infrastructure of the NHS to help support healthier choices. Measures like dedicated alcohol care teams in hospitals, or targeted anti-smoking interventions aimed at CVD patients.

But increasingly we understand that there are effective, non-clinical approaches to healthier living and ageing.

Look at the use of homeshares to tackle loneliness. Bringing together people with spare rooms and people who are happy to chat and lend a hand around the house in return for affordable accommodation.

Or take the social prescribing revolution.

A growing body of evidence suggests that activities like joining a book group or singing in a choir or learning to play an instrument can have huge health and wellbeing benefits.

Benefits that include everything from sleep quality to reduced anxiety to improved memory.

Over the next few years we want to bring these kinds of treatments to almost a million people.

Weve set up a National Academy for Social Prescribing to aimed at making the NHS a world-leader in this field.

Third, and this wont be a surprise coming from me, is better technology.

More proactive, preventative healthcare depends on a strong data infrastructure. On being able to link disparate datasets from different parts of the system to create a complete narrative about a persons care.

Lets take an example.

We know that atrial fibrillation irregular heartbeat is a common cause of stroke, but the risk varies from person to person.

By analysing lots of different data points for atrial fibrillation patients age, frailty, previous bleeding and so on you can create an individualised risk score.

In turn, this allows GPs to take pre-emptive action, for example prescribing anticoagulants.

In the past assembling all the information needed to produce that score was so time-consuming as to be impractical. It was held on different databases in different formats, often as free text rather than machine-readable code.

But now we can do it with AI.

In fact, a team right here at Kings Dr Dan Bean and Dr Paul Scott have built an AI tool thats able to replicate the analysis of human experts in a fraction of the time.

Adult social care is increasingly a site of healthtech innovation.

Internet-linked devices can help people live at home for longer and stay connected to family and friends.

They can also help providers deliver smarter, more responsive care.

For example, theres a provider up in Warwickshire WCS Care doing great things with acoustic monitoring.

The tech lets the staff hear crying or breathing problems, sending an alert to a monitoring station staffed by a night manager.

It means that staff arent knocking on residents doors every hour and disturbing people.

Everyone sleeps better, and staff estimate that night-time falls have reduced by 34%.

Interestingly, when they analysed the data they found that lots of people were staying awake late into the night.

This led the care home to set up a wide awake club to support night owls and get them back into a healthier rhythm.

I want to spread this kind of innovation far and wide, and Ive set up a dedicated adult social care unit in NHSX.

This will focus on setting technical standards, improving data sharing, enhancing skills and fixing the digital infrastructure.

Like longevity itself, better tech is an opportunity we wholeheartedly embrace.

Ill end where I began, and this is the message I want to leave you with.

Longer life is not a problem to be tackled but a goal to be pursued.

And not just for government, or even the NHS, but for each and every one of us.

Theres a huge prize ahead if we get this right: 5 more years of healthy life. More enjoyment out of life. More time for the things that matter most in life.

Im looking forward to working with you all to make it happen.

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Adding years to life and life to years: our plan to increase healthy longevity - GOV.UK

Expert in Aging, Ken Dychtwald, to Deliver Keynote Address. Powerhouse Speakers Represent AARP, NIA, Ziegler LinkAge, Home Instead.

ATLANTA, Feb. 7, 2020 /PRNewswire/ -- What's Next Longevity Business Summit kicks off its 17th year as the premier curator of 300 thought leaders in aging March 26, 2020 at the Hyatt Regency Atlanta with networking and discussions about trends, innovations and opportunities for serving age 50+ consumers. The conference will feature power-packed panels on the theme of "Mobility, Memory, Money and Marketing" and how to capitalize on the $7.6 trillion longevity economy.

"This summit is like earning a mini-MBA in the longevity market," said Mary Furlong, a successful entrepreneur and author in aging. Her company, Mary Furlong & Associates,has produced What's Next summits for 17 years to spot trends, match investors with innovators and close deals in the lucrative longevity market. "There's a gold mine in the golden years. In 2020, I believe we will see more women at the epicenter of global purchasing power and innovative solutions for an aging society."

Entrepreneurs will hear from investors Ziegler LinkAge, Nationwide Ventures and Portfolia on how to obtain funding; companies like Home Instead about opportunities in deal-making with distribution partners; top research agencies about customer insights and market research trends; researchers about innovative programs driving dementia care and brain health and so much more.

This year's keynote address, "The Next Wave: How Boomer Retirees Will Redefine Money, Consumerism, Family, Work, Housing, Mobility, Health and Success," will feature one of the visionaries in aging, Ken Dychtwald, author and co-founder of Age Wave.

"I'm looking forward to sharing my latest ideas on which industries, products and services will dominate the emerging longevity marketplace many of which are hiding in plain sight," said Dychtwald. "I'll be covering everything from medical technologies on the horizon that have the potential to dramatically transform health and aging to how aging baby boomers' time affluence will redefine the travel and leisure, housing, education, media and financial services industries."

Maddy Dychtwald, author and Age Wave co-founder, will moderate an inspirational panel of businesswomen discussing female economic influence and fiscal makeovers for 2020 and beyond.

Summit attendees will receive business coaching on: scaling a business; leveraging senior housing and transportation deals; delivering for home as the new health hub; using emerging technology including Virtual Reality, Voice First and Artificial Intelligence to change consumer habits and enhance workforce development; understanding fintech and privacy issues; changes in Medicare Advantage reimbursement models; how to incorporate aging vitality and caregiver wellness into a business model; marketing success using content development and social media; designing with aging in mind and more.

What's Next Longevity Business Summit is co-produced by Lori Bitter, founder of The Business of Aging, and Sherri Snelling, CEO of Caregiving Club,and has been held concurrent with the American Society of Aging's annual Aging in America conference for the last 17 years. Summit lead sponsors include AARP Innovation Labs, GreatCall, Ageless Innovation, CareLinx, VitalTech, Medterra CBD, The Business of Aging, Susan Davis International, Caregiving Club, iN2L, Hamilton CapTel, Home Instead, myFamilyChannel, SilverRide, Outpatient, Naboso Technology, Nationwide, Portfolia, Embodied Labs, Caremerge, Stay Smart Care and Thrive. Visit boomersummit.com for more information.

About Mary Furlong/Mary Furlong & Associates

Founded in 2003, Mary Furlong & Associates (MFA) is a strategy, business development and marketing company. A serial entrepreneur, Mary founded SeniorNet.org, and ThirdAge Media (acquired by Ancestry.com), prior to MFA. For 17 years, Mary has produced the industry leading What's Next Longevity Business Summit and Silicon Valley Boomer Venture Summit, adding the Washington Innovation Summit and What's Next Canada in recent years. Author of Turning Silver into Gold, How to Profit in the Boomer Market and The MFA Longevity Market Report, Mary has been recognized by ASA, Fortune, Time and as one of the top 100 Women in Silicon Valley. She is an adviser to the Ziegler LinkAge Fund, CABHI and numerous startup companies in addition to her private client practice.

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About Lori Bitter/The Business of Aging

Lori K. Bitter provides strategic consulting, research and development for companies seeking to engage with mature consumers at her consultancy, The Business of Aging. Her current research, Hacking Life Shifts, in collaboration with RTI research and Collaborate, was championed by AARP, and funded by Proctor & Gamble, Bank of America, Unilever and others. She is a 2017 Influencer in Aging, named by Next Avenue and author ofThe Grandparent Economy. She was president of J. Walter Thompson's Boomer division, JWT BOOM, the nation's leading mature market advertising and marketing company, and led that firm's annual Boomer marketing event for five years.

About Sherri Snelling/Caregiving Club

Sherri Snelling is a corporate gerontologist and founder/CEO of Caregiving Club, a strategic consulting and content creation firm focused on biopsychosocial aging, Alzheimer's and caregiver wellness. Her innovative wellness programs include the Me Time Monday and 7 Ways to Caregiver Wellness workshops. She is the author of A Cast of Caregivers Celebrity Stories to Help You Prepare to Care, a contributing columnist and national speaker on caregiving and has done work for AARP, Keck Medicine of USC, UnitedHealthcare, Wells Fargo, Goldman Sachs, LifeCare, QVC. She was chairman of the National Alliance for Caregiving and is on an Alzheimer's Association board.

Contact:

Jennifer BantaEvent Manager(925) 405-2217233385@email4pr.com

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There's a Gold Mine in the Golden Years: What's Next Longevity Business Summit Helps Entrepreneurs Tap $7 Trillion Market - Yahoo Finance

KEY POINTS

Zion Williamson is as good as advertised but his weight remains a critical issue. Being the third heaviest player behind Tacko Fall and Boban Marjanovic, there is no question that the top pick of the 2019 NBA Draft needs to shed off some weight if he wants to play pro ball continuously.

Currently at 284 pounds, Williamson is about the same weight as Nikola Jokic of the Denver Nuggets. Among the top five players in the NBA, he is the only one who is undersized and is not a center. Though most reason that Charles Barkley was able to survive with that frame during his prime, the NBA today is far different.

For now, all Williamson can do is heed the advice of the New Orleans Pelicans. He needs to think long-term and be made aware that longevity counts, ESPN reported. The good news is that the 19-year-old is listening, aware that all of this is for his own good. He sat out the game against their game against the Indiana Pacers but returned emphatically with a star-caliber performance against the Portland Trail Blazers, Yahoo Sports reported.

The minutes of Williamson for the Pelicans for the remainder of the season will be interesting. New Orleans currently sits at the 11th spot of the NBA Western Conference with a 23-31 win-loss card. With a string of wins, the Pels could catch the last bus to the NBA playoffs. However, they are likely to encounter rough sailing getting beyond the first round.

New Orleans could be tempted to field in Williamson and go beyond the managed minutes they have in place. But the risk behind that could be catastrophic, placing the former Duke Blue Devil's future at risk. Based on his showing against the Blazers, there is no denying that Williamson is a future star but adjustments are needed as far as his playing weight is concerned.

Williamson is likely to work on his weight problem by the summer. If he intends to play continuously and longer, he needs to burn some calories and reach the ideal playing weight for a 6-foot-6 individual. A look at multicare.org shows that someone who stands at that height would ideally have a weight ranging from 193 to 235 lbs. Doing the math, this means Williamson will need to shed off about 50 pounds or more to be at his optimum best. This could also help address potential injuries such as his knees, something that kept him from playing the earlier part of the 2019-20 NBA season.

Zion Williamson seems bent on joining the Phoenix Suns next NBA season. Zion Williamson #1 of the Duke Blue Devils looks on against the Michigan State Spartans in the East Regional game of the 2019 NCAA Men's Basketball Tournament at Capital One Arena on March 31, 2019 in Washington, DC. Photo: Getty Images/Patrick Smith

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NBA Rumors: Zion Williamson Longevity Comes First, Losing Weight Strongly Urged - International Business Times

A staff member sets up a conference room at the Congress Centre ahead of the annual meeting of the World Economic Forum in Davos.

Photo: Fabrice Coffrini/AFP via Getty Images

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The 2020 World Economic Forum (WEF) in Davos shone its annual January spotlight on global concerns with a lot of expert dialogue. As always, the mindset of organizational leadership was focused on the search for solutions and in todays world, the challenges feel especially urgent.

Consider a few of the themes that emerged this year at Davos. There was, for example, a high level of debate about how to measure progress on topics such as environmental, social and governance (ESG)-aligned investing and achieving positive societal change and sustainability. And the issue of longevity and the realities of living longer and working longer face all organizations.

Climate change was very much top of mind, though, as reflected in the 2020 Global Risks Report published by the WEF with the support of Marsh & McLennan, in which the top five risks cited in the report had to do with climate. Measuring real change and avoiding greenwashing (unsubstantiated claims about environmental benefits) is important. Companies making efforts to achieve positive change are driven by a desire to do the right thing as well as to stay ahead of looming regulation. This is driving innovation for example, in shipping, where global firms have self-regulated and are working to reduce emissions through new designs and technology.

Unsurprisingly, there was much discussion of the risk of a pandemic, given the current coronavirus outbreak in China. However, the risk of noncommunicable diseases was recognized as a bigger issue. Most countries spend increasingly more on managing health, but its just as important to continue investing in good health promotion, especially disease prevention and addressing social determinants of health to keep people out of hospitals, as that is where the cost of health care dramatically rises. This becomes even more important in the context of todays aging populations.

Meanwhile, innovative investors are taking action to address key global risks, as noted at an executive dialogue at Davos focused on Transformational Investment. A panel of leaders from sovereign wealth and pension funds large-asset funds that can make a real difference in world markets discussed how they can transform capitalism through co-investment and co-creation with business partners. Together they are addressing risks such as climate change, water scarcity, populism and extreme weather events.

Another key theme: While theres been increased momentum toward achieving gender diversity, we still have far to go, according to the newest WEF Gender Gap Report. The discussion on gender diversity has shifted from building the case to putting plans into action, and there are more men in the conversation. A hopeful view is that we have built some muscle for gender diversity, which gives us a path to drive other forms of diversity, including age diversity.

Mercers 2020 When Women Thrive, Businesses Thrive research, to be released in March, was previewed at Davos as well. Some bright spots: 86% of participating companies say improving D&I is high or very high on their agenda, and 66% say senior executives are now actively engaged in D&I. And nearly half (48%) of companies say that men are engaged in gender equality efforts, up from 38% in 2016. Plus, the number of women at executive levels has increased 3% since 2016.

Unfortunately, the new research also shows that companies are behind in the area of accountability for D&I progress. Slow progress on that front calls for leaders who align the values of diversity and inclusion throughout the organization not just as a mandate, but as a powerful component of the culture.

Another Davos event, focused on longevity, Redesigning Retirement for Longer Working Lives, got to the heart of the challenge.

Lets be clear. Longevity is one aspect of a brighter future for the worlds workforce, so long as organizations and leadership get it right. It calls for a change of mindset, adapted health care and savings programs, more opportunities for continuous learning and, of course, longer careers. Its a chance for employers and experienced workers to embrace upskilling, reskilling and continuously adapting.

Theres no doubt that longevity is a serious social issue. Life expectancies are increasing globally, and children born today are likely to live beyond the age of 100. Already, at many of Mercers clients, the ratio of employees 50 years and older compared to the rest of the workforce has doubled in just five years with people living and working longer, its clear much of our world will look much older in the years ahead.

In partnership with Mercer, the WEFexamined data for retirement savings, including both government and company pensions as well as individual savings, from eight major economies. In the U.S., it is expected that people will outlive their savings by almost 10 years. When we look at Europe, the gap grows to 11.5 years, and in Japan its nearly 18 years.

A number of large employers and policymakers in countries and industry sectors most affected by an aging population attended the Mercer longevity event and crafted practical solutions to some of our identified personas. For example:

The longevity event at Davos offered an optimistic view, and attendees seemed passionate about the possibilities. Longevity is a reality that companies and employees cant ignore if theyre going to build sustainable futures over the short- and long term. Events like this can help organizations and their leaders to find their purpose, and purpose-led companies are destined for the long haul. They are the sort of companies that define Davos to make the future brighter for everyone.

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Reflecting on Davos and Its Most Urgent Themes - BRINK

MAPLEWOOD, NJ -- Maplewoods oldest business, Woolley Home Solutions, spoke with TAPintoTV about their long history in town and how they've been able to maintain their success for 95 years.

Its a lot to live up to, said Norman E. Woolley. Its important to support the town thats allowed you to thrive and be able to be successful for that long.

The family-owned company started in 1924, specializing in coal and ice delivery. As fuels changed, the business changed with them, evolving into a fuel oil and heating business by the end of World War 2.

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Change is a big thing, said Norman W. Woolley, Jr. I think you have to change, you cant stay where you are.

Five years ago, they diversified their business and rebranded as Woolley Home Solutions, offering added services like HVAC, sewer and plumbing. Its making sure that everybodys comfortable in the entire house, said Norman E. Woolley, and making sure it can be as efficient as possible.

While the company still sells fuel, such as home heating oil and propane, they also offer more environmentally-friendly products, like bioheat and biodiesel. In fact, Woolley installed the very first biodiesel station in New Jersey. The companys plan is to be carbon-neutral by 2050.

What are some ways Woolley has maintained its success over the years? We all learned the business from the ground up, said Norman W. Woolley, Jr. I think thats an important thing to do.

The company also prides itself on excellent customer service. Your best marketing is your customer telling their neighbor about how happy the experience they had with us, Norman E. Woolley.

To learn more about Woolleys products, services, and history, visit them online at http://www.woolleyfuel.com.

Editors Note: Woolley Home Solutions is an advertiser of TAPintoSOMA.

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Small Business Spotlight: Maplewood, NJ's Oldest Business Shares the Lessons of their Longevity - TAPinto.net

With more than 140 years of heritage to its name, the homegrown TCM brand is still breaking new ground in Singapore

Eu Yan Sang may have started off in Singapore with one clinic in 2002, but today, the brand has more than 20 traditional Chinese medicine (TCM) clinics islandwidea new addition at Chinatown Point recently opened in October 2019.

The brands clinics have three different concepts, each catering to a different need. The Eu Yan Sang TCM Clinic serves patients in the heartlands and aims to help with acute and chronic illnesses, while the Eu Yan Sang TCM Wellness Clinic helps patients with sub-health, skin as well as weight and pain management; it offers travel health solutions for busy executives, too. The Eu Yan Sang Premier TCM Centre is managed by a team of experienced physicians who are trained to manage complex or chronic health conditions through a combination of prescribed herbal medication, acupuncture, tui na and cupping.

(Related: Now A Century-Old, Eu Yan Sang Has Transformed Holistic Healthcare)

Eu Yan Sangs longevity can be credited to its balanced use of technology and tradition. While it prioritises a holistic health and wellness approach thats based on its centuries-old TCM heritage, Eu Yan Sang has simultaneously built a reputation for quality, safety and innovation.

We aim to demystify TCM for the modern patient through continuous learning and by upgrading and adapting our practices, which are supported by rigorous standards in terms of structures, processes and controls, explains Lim Swee Cheng, general manager (clinic services and operational excellence) at Eu Yan Sang.

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Technology and Tradition are at the Heart of Eu Yan Sang's Longevity - Singapore Tatler

Michael Cusumano agrees. Hes a professor at the Massachusetts Institute of Technology who spearheaded entrepreneurship and innovation initiatives at the Tokyo University of Science from 2016 to 2017, and lived and worked in Japan for eight years. Closing a company or selling it is also considered something of a failure and shame in Japan, and this feeling goes back centuries. So these cultural issues also seem to encourage families to keep firms going, he says. Japanese society, and the economy, is not as flexible as the US, and so Japan does not generate big new firms so easily. The tendency is to preserve what they have.

Yet shinise companies arent exempt from hardship. Kongo Gumi, a construction company founded back in 578, lasted a staggering 1,400 years before going into liquidation in 2006 due to debt. In the future, Matsuzaki believes that there will be benefits in combining the strengths of the two business models.

The key will be to foster more synergy between shinise companies and start-ups, she says. Shinise companies strength in resources, their reputation in the industry, [a] strong network. By mixing new technology and rapid decision-making with shinise, she thinks start-ups can become a lethal weapon for Japan's future.

Yet back at Tsuen Tea, current owner Tsuen has no such lofty goals. I was born here by chance. My ancestors continued the tea business and Im taking over, Tsuen says. My goal is not to make the company bigger or expand sales or go worldwide. Whats most important is to just continue this.

Additional reporting by Yoko Ishitani and Mari Murakami.

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Why so many of the world's oldest companies are in Japan - BBC News

A pair of juniors and a pair of true freshmen pitchers will need to transition into starters quickly in order to fill the biggest holes in Cal Poly Baseballs roster.

Junior righthander Taylor Dollard and junior southpaw Andrew Alvarez bring experience to the weekend pitching ranks, while freshmen righthanders Drew Thorpe and Derek True will be jumping straight into the action in their first collegiate season.

Were thin, but weve got a good group of guys that work hard, pitching coach Jake Silverman said. Its going to take every single one of them for us to be successful this year

Cal Poly lost two All-Big West first team pitchers from last season. Friday starter Bobby Ay (9-1, 3.27 ERA) was a ninth round draft pick of the Arizona Diamondbacks while top reliever Michael Clark (6-3, 2.61 ERA, eight saves) graduated.

Dollard (5-0, 2.89 ERA, 4 saves) will take over as the Friday starter.

The last two years, [Dollards] just been a huge impact on this team, Alvarez said. Now, having him as a Friday starter, hes hopefully going to take the role of Bobby Ay and exceed that level.

Dollard was also an All-Big West first team selection following his successful sophomore season as a reliever. Cal Polys season opener against Connecticut on Friday, Feb. 14 will be his first collegiate start.

Ive been working really hard to become a starter, Dollard said. Its something Ive wanted since I stepped on campus.

Dollards most impressive performance came in Cal Polys final match of the season against UC Santa Barbara. In the Friday game, Dollard pitched two hitless innings and recorded four strikeouts. The next day, he pitched six innings in relief to continue the Mustangs hopes of reaching the postseason.

Dollard has had success out of the bullpen for his entire Cal Poly career. He earned three wins and three saves through 19 appearances as a freshman in the 2018 season. Last season, he improved to five wins and four saves through another 19 appearances.

When it comes to attitude and mentality, he has it, Silverman said. The biggest thing for him is learning the longevity of a season with 15 starts.

Alvarez (1-3, 5.10 ERA), who began the 2019 season as a reliever, will be the Saturday starter.

The junior southpaw will be completing his transition into a starting pitcher, which began last year. In the last six weeks of the 2019 season, Alvarez had six starts.

It was something I didnt really expect coming into my sophomore year, Alvarez said. Before, I was just a lefty specialist. One or two at bats a night. Then, I was facing multiple hitters, multiple innings. So its really allowed me to grow.

When transitioning from a reliever to a starter, the focus is on shifting the pitchers mindset to be focused on longevity, according to Silverman.

When youre a starter, youre going to take punches and youre going to take some hits, Silverman said. You gotta just keep working through those and pitching out of problems.

A pair of true freshman will round out the pitching lineup. Drew Thorpe, from Washington, Utah is expected to be the Sunday starter while Santa Barbara native Derek True will be the Tuesday opener.

Thorpe had a 7-1 record and a 1.93 ERA in his senior season at Desert Hills High School. A three-time All-Utah honoree, Thorpe said he was excited when head coach Larry Lee told him he would begin the season as a starter.

Its what Ive been working for since I got here, Thorpe said. As a freshman, thats pretty cool to come in and be one of the weekend guys.

Hes a guy that can eat up a lot of innings because he has the ability to get you out in multiple ways, Silverman said. Hes the type of guy that has some longevity with what hes going to do too.

True, also a righthander, had a perfect 9-0 season with a 2.20 ERA to close out his career at Santa Barbara High School.

Coming here to play for coach lee, its just an honor, True said. Not too many people can say that. Hes one of the best coaches in the country, if not the best. So having that opportunity was a no-doubter for me.

In his senior season, True was named the league MVP after recording 75 strikeouts over 57 1/3 innings. Silverman called True a really nice surprise.

Hes got a chance to throw really hard and have power stuff, Silverman said. He just has to learn how to wrangle that in He has the makings to be something special.

The Mustangs will begin its tough non-conference schedule at the MLB4 Tournament in Scottsdale, Ariz. from Feb. 14-16. After facing Connecticut Friday, Cal Poly will take on defending national champion Vanderbilt on Saturday and runner-up Michigan on Sunday.

The older guys, they have experience So theyve been battle tested, Silverman said. The younger guys, they just have to learn from it. theyre going to take the licks a little bit, but as long as they just take the experience that they get and use it day to day, itll be an incredible information gathering on their behalf to get better.

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Baseball brings a new lineup of starting pitchers into the 2020 season - Mustang News